1DR2A

2.3 angstroms crystal structure of chicken liver dihydrofolate reductase complexed with thionadp+ and biopterin
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
186
structure length
186
Chain Sequence
VRSLNSIVAVCQNMGIGKDGNLPWPPLRNEYKYFQRMTSTSHVEGKQNAVIMGKKTWFSIPEKNRPLKDRINIVLSRELKEAPKGAHYLSKSLDDALALLDSPELKSKVDMVWIVGGTAVYKAAMEKPINHRLFVTRILHEFESDTFFPEIDYKDFKLLTEYPGVPADIQEEDGIQYKFEVYQKSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Gallus gallus
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 51
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1992-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1dr2A00
1RF7A 3EEJA 1DR7A 4H96A 1DR2A 3KFYA 3FQZA 4HOEA 3D80A 3IA4A 2JYBA 2W9HA 3RG9A 4P3QA 2W3MA 4X5GA 2O7PA 4KY8A 4XT4A 4PSYA 4XECX 3QL3A 3QG2A 4PSSA 1DF7A 2CIGA 3QLWA 5HF2X 3LG4A 3IRNA 3S7AA 1MVSA 2L28A 1DRBA 4XT5A 1RB2A 2QK8A 3FRAX 4M7VA 1S3WA 3CSEA 2D0KA 1RX7A 3GHCA 3QLRA 1J3IA 5HQZA 3ZPGA 5FDAA 3QGTA 1RX3A 3FRFX 1KMVA 4KBNA 1DHJA 3FY9X 4TU5X 4KJJA 1IA1A 4QLEA 3S3VA 4LAEX 4I13A 2BLAA 2W3AA 1SEJA 4EIZA 1RX8A 3IA5A 2ITHA 2D5NA 3SQYX 4ELHA 5EAJA 4M6LA 1IA2A 1D1GA 3UM8A 4EILA 5HPBA 1VDRA 3F91A 3JW5A 3NXXA 3CD2A 3FL8A 3DATA 3SA2A 1DR4A 8DFRA 1AOEA 4EJ1A 3EIGA 1PDBA 1PD8A 3D84X 3DAUA 3GHWA 2G6VA 3JTWA 2P4GA 1DRFA 3IRMA 4QLFA 4GH8A 2C2SA 3FQOA 4KJKA 4LEKX 5DFRA 3UM6A 5E8QA 4Q0EA 4PTHA 2INQA 1JOLA 4P68A 2OIPA 3QLYA 4I1NA 1DR3A 3DRCA 1E26A 3E0BA 4DDRA 4HOGA 2W3WA 3I8AX 1TDRA 1S3UA 4LAGX 1DG8A 4G8ZX 3TD8A 1HFRA 4KJLA 1RA9A 2HXVA 4IXED 1DIUA 4XE6X 5CC9A 3NXRA 3K45A 1DISA 3FREX 4QLGA 4Q67A 5ECCA 1DYRA 1JOMA 3CLBA 1IA3A 1DAJA 1DREA 3DL6A 1S3VA 3FL9A 1RX1A 3JWCA 4PTJA 5HF0X 3NZCX 1DR1A 1DG7A 3SGYA 4G3MA 1YHOA 3SRQX 1CD2A 1DHIA 4XT8A 1M79A 1RD7A 1DR6A 4KYAA 3EEMA 3VCOA 3NU0A 1DRHA 4CD2A 3EELA 4PDJA 3N0HA 2FZIA 3F0VX 4RGCA 5U27A 4EIGA 4M6KA 3ZPCA 3TQ8A 3QLZA 1DDRA 3NTZA 4ECKA 1RA1A 4X5HA 3NZ9X 3M09A 3SH2A 1BOZA 1RX9A 3DG8A 3NXYA 3FYVX 3NZ6X 1DDSA 4DFRA 3HBBA 3IX9A 1DYIA 1M78A 3F0XX 3L3RA 4DP3A 5DXVA 1RA2A 1CZ3A 1DHFA 1U72A 1RX2A 2W9TA 1RX6A 1M7AA 2CD2A 3K2HA 2W3BA 3FYWX 3FQVA 1DG5A 3OCHA 3SA1A 1RA3A 1KMSA 3FQ0A 1DLRA 2DRCA 1DR5A 3INVA 4IXGX 3SRUX 1ZDRA 1DRAA 3KJRA 4XT7A 3NZBX 4HA7A 1RE7A 3SRRX 3NRRA 2KGKA 1J3KA 3QL0A 3FS6A 2BLCA 3JVXA 4DPHA 2ZZAA 2H2QA 4KM2A 4KNEA 3SRSX 3JW3A 3GYFA 3UM5A 4XRBA 5HVBA 5HUIA 5JG0X 3DGAA 5HQYA 1MVTA 4KM0A 4QJZD 3FY8X 1PD9A 3KY8A 3F0QX 5HT5A 4X5FA 2GD9A 3NXVA 3M08A 2AZNA 3SRWX 1OHJA 3DFRA 3TQBA 3FQCA 3KJSA 1U70A 3HJ3A 3JWMA 1AO8A 3Q1HA 4ELGA 1RG7A 3SAIA 4QHVA 4M2XA 3GHVA 5HSUA 1AI9A 4QI9A 1LY3A 3OAFA 4KL9A 4H97A 2LF1A 3QYOA 2W9SA 3RO9A 4KFJA 3F0SX 3JSUA 1DYHA 4LAHX 5U26A 4Q6AA 4G95A 3CL9A 3QFXA 2BL9A 1KLKA 4ELEA 3JWKA 1S3YA 5HVEA 5JA3A 3F8ZA 1OHKA 4Q0DA 1JUVA 4OR7A 2HM9A 3NZDA 7DFRA 5ECXA 3GI2A 4KAKA 3F8YA 4H98A 3QLXA 3DL5A 3R33A 4OSGA 1RH3A 4KEBA 4KY4A 3JWFA 1U71A 3IROA 3ROAA 4PSTA 3NXTA 4IXFX 4NX6A 3F0UX 4ELBA 1HFQA 1RX5A 4P66A 4HA9A 1DYJA 3NXOA 4P3RA 5HI6A 2C2TA 1IA4A 4M6JA 3EEKA 1LUDA 1RC4A 1VJ3A 4KD7A 4M7UA 1LY4A 1RX4A 3EX8A 3I3RA 1DLSA 2DHFA 2ANOA 3KGYA 3S9UA 5HT4A 3K47A 1HFPA 4QJCA 3K74A 4H95A 2FZJA 2OBCA 3TQ9A 4HOFA 4FGHA 2ANQA 3FRDX 3QLSA 2HQPA 2B3ZA 4X5JA 4FGGA 2BLBA 4X5IA 1QZFA 2FZHA 1RA8A 1RB3A 2W9GA 3FRBX 4ELFA 4FHBA 4NX7A 4XT6A 4KLXA 1BZFA 5HSRA 4DPDA 1J3JA 2XW7A 3FQFA 3F0BX 3SR5X 6DFRA 2W3VA 3NZAX 3QYLA 5CCCA 3TQAA
chains in the Genus database with same CATH superfamily
1RF7A 3EEJA 1DR7A 4H96A 1DR2A 3KFYA 3FQZA 4HOEA 3D80A 3IA4A 2JYBA 2W9HA 3RG9A 4P3QA 2W3MA 4X5GA 2O7PA 4KY8A 4XT4A 4PSYA 4XECX 3QL3A 3QG2A 4PSSA 1DF7A 2CIGA 3QLWA 5HF2X 3LG4A 3IRNA 3S7AA 1MVSA 2L28A 1DRBA 4XT5A 1RB2A 2QK8A 3FRAX 4M7VA 1S3WA 3CSEA 2D0KA 1RX7A 3GHCA 3QLRA 1J3IA 5HQZA 3ZPGA 5FDAA 3QGTA 1RX3A 3FRFX 1KMVA 4KBNA 1DHJA 3FY9X 4TU5X 4KJJA 1IA1A 4QLEA 3S3VA 4LAEX 4I13A 2BLAA 2W3AA 1SEJA 4EIZA 1RX8A 3IA5A 2ITHA 2D5NA 3SQYX 4ELHA 5EAJA 4M6LA 1IA2A 1D1GA 3UM8A 4EILA 5HPBA 1VDRA 3F91A 3JW5A 3NXXA 3CD2A 3FL8A 3DATA 3SA2A 1DR4A 8DFRA 1AOEA 4EJ1A 3EIGA 1PDBA 1PD8A 3D84X 3DAUA 3GHWA 2G6VA 3JTWA 2P4GA 1DRFA 3IRMA 4QLFA 4GH8A 2C2SA 3FQOA 4KJKA 4LEKX 5DFRA 3UM6A 5E8QA 4Q0EA 4PTHA 2INQA 1JOLA 4P68A 2OIPA 3QLYA 4I1NA 1DR3A 3DRCA 1E26A 3E0BA 4DDRA 4HOGA 2W3WA 3I8AX 1TDRA 1S3UA 4LAGX 1DG8A 4G8ZX 3TD8A 1HFRA 4KJLA 1RA9A 2HXVA 4IXED 1DIUA 4XE6X 5CC9A 3NXRA 3K45A 1DISA 3FREX 4QLGA 4Q67A 5ECCA 1DYRA 1JOMA 3CLBA 1IA3A 1DAJA 1DREA 3DL6A 1S3VA 3FL9A 1RX1A 3JWCA 4PTJA 5HF0X 3NZCX 1DR1A 1DG7A 3SGYA 4G3MA 1YHOA 3SRQX 1CD2A 1DHIA 4XT8A 1M79A 1RD7A 1DR6A 4KYAA 3EEMA 3VCOA 3NU0A 1DRHA 4CD2A 3EELA 4PDJA 3N0HA 2FZIA 3F0VX 4RGCA 5U27A 4EIGA 4M6KA 3ZPCA 3TQ8A 3QLZA 1DDRA 3NTZA 4ECKA 1RA1A 4X5HA 3NZ9X 3M09A 3SH2A 1BOZA 1RX9A 3DG8A 3NXYA 3FYVX 3NZ6X 1DDSA 4DFRA 3HBBA 3IX9A 1DYIA 1M78A 3F0XX 3L3RA 4DP3A 5DXVA 1RA2A 1CZ3A 1DHFA 1U72A 1RX2A 2W9TA 1RX6A 1M7AA 2CD2A 3K2HA 2W3BA 3FYWX 3FQVA 1DG5A 3OCHA 3SA1A 1RA3A 1KMSA 3FQ0A 1DLRA 2DRCA 1DR5A 3INVA 4IXGX 3SRUX 1ZDRA 1DRAA 3KJRA 4XT7A 3NZBX 4HA7A 1RE7A 3SRRX 3NRRA 2KGKA 1J3KA 3QL0A 3FS6A 2BLCA 3JVXA 4DPHA 2ZZAA 2H2QA 4KM2A 4KNEA 3SRSX 3JW3A 3GYFA 3UM5A 4XRBA 5HVBA 5HUIA 5JG0X 3DGAA 5HQYA 1MVTA 4KM0A 4QJZD 3FY8X 1PD9A 3KY8A 3F0QX 5HT5A 4X5FA 2GD9A 3NXVA 3M08A 2AZNA 3SRWX 1OHJA 3DFRA 3TQBA 3FQCA 3KJSA 1U70A 3HJ3A 3JWMA 1AO8A 3Q1HA 4ELGA 1RG7A 3SAIA 4QHVA 4M2XA 3GHVA 5HSUA 1AI9A 4QI9A 1LY3A 3OAFA 4KL9A 4H97A 2LF1A 3QYOA 2W9SA 3RO9A 4KFJA 3F0SX 3JSUA 1DYHA 4LAHX 5U26A 4Q6AA 4G95A 3CL9A 3QFXA 2BL9A 1KLKA 4ELEA 3JWKA 1S3YA 5HVEA 5JA3A 3F8ZA 1OHKA 4Q0DA 1JUVA 4OR7A 2HM9A 3NZDA 7DFRA 5ECXA 3GI2A 4KAKA 3F8YA 4H98A 3QLXA 3DL5A 3R33A 4OSGA 1RH3A 4KEBA 4KY4A 3JWFA 1U71A 3IROA 3ROAA 4PSTA 3NXTA 4IXFX 4NX6A 3F0UX 4ELBA 1HFQA 1RX5A 4P66A 4HA9A 1DYJA 3NXOA 4P3RA 5HI6A 2C2TA 1IA4A 4M6JA 3EEKA 1LUDA 1RC4A 1VJ3A 4KD7A 4M7UA 1LY4A 1RX4A 3EX8A 3I3RA 1DLSA 2DHFA 2ANOA 3KGYA 3S9UA 5HT4A 3K47A 1HFPA 4QJCA 3K74A 4H95A 2FZJA 2OBCA 3TQ9A 4HOFA 4FGHA 2ANQA 3FRDX 3QLSA 2HQPA 2B3ZA 4X5JA 4FGGA 2BLBA 4X5IA 1QZFA 2FZHA 1RA8A 1RB3A 2W9GA 3FRBX 4ELFA 4FHBA 4NX7A 4XT6A 4KLXA 1BZFA 5HSRA 4DPDA 1J3JA 2XW7A 3FQFA 3F0BX 3SR5X 6DFRA 2W3VA 3NZAX 3QYLA 5CCCA 3TQAA
chains in the Genus database with same CATH topology
1RF7A 3EEJA 1DR7A 4H96A 1DR2A 3KFYA 3FQZA 4HOEA 3D80A 3IA4A 2JYBA 2W9HA 3RG9A 4P3QA 2W3MA 4X5GA 2O7PA 4KY8A 4XT4A 4PSYA 4XECX 3QL3A 3QG2A 4PSSA 1DF7A 2CIGA 3QLWA 5HF2X 3LG4A 3IRNA 3S7AA 1MVSA 2L28A 1DRBA 4XT5A 1RB2A 2QK8A 3FRAX 4M7VA 1S3WA 3CSEA 2D0KA 1RX7A 3GHCA 3QLRA 1J3IA 5HQZA 3ZPGA 5FDAA 3QGTA 1RX3A 3FRFX 1KMVA 4KBNA 1DHJA 3FY9X 4TU5X 4KJJA 1IA1A 4QLEA 3S3VA 4LAEX 4I13A 2BLAA 2W3AA 1SEJA 4EIZA 1RX8A 3IA5A 2ITHA 2D5NA 3SQYX 4ELHA 5EAJA 4M6LA 1IA2A 1D1GA 3UM8A 4EILA 5HPBA 1VDRA 3F91A 3JW5A 3NXXA 3CD2A 3FL8A 3DATA 3SA2A 1DR4A 8DFRA 1AOEA 4EJ1A 3EIGA 1PDBA 1PD8A 3D84X 3DAUA 3GHWA 2G6VA 3JTWA 2P4GA 1DRFA 3IRMA 4QLFA 4GH8A 2C2SA 3FQOA 4KJKA 4LEKX 5DFRA 3UM6A 5E8QA 4Q0EA 4PTHA 2INQA 1JOLA 4P68A 2OIPA 3QLYA 4I1NA 1DR3A 3DRCA 1E26A 3E0BA 4DDRA 4HOGA 2W3WA 3I8AX 1TDRA 1S3UA 4LAGX 1DG8A 4G8ZX 3TD8A 1HFRA 4KJLA 1RA9A 2HXVA 4IXED 1DIUA 4XE6X 5CC9A 3NXRA 3K45A 1DISA 3FREX 4QLGA 4Q67A 5ECCA 1DYRA 1JOMA 3CLBA 1IA3A 1DAJA 1DREA 3DL6A 1S3VA 3FL9A 1RX1A 3JWCA 4PTJA 5HF0X 3NZCX 1DR1A 1DG7A 3SGYA 4G3MA 1YHOA 3SRQX 1CD2A 1DHIA 4XT8A 1M79A 1RD7A 1DR6A 4KYAA 3EEMA 3VCOA 3NU0A 1DRHA 4CD2A 3EELA 4PDJA 3N0HA 2FZIA 3F0VX 4RGCA 5U27A 4EIGA 4M6KA 3ZPCA 3TQ8A 3QLZA 1DDRA 3NTZA 4ECKA 1RA1A 4X5HA 3NZ9X 3M09A 3SH2A 1BOZA 1RX9A 3DG8A 3NXYA 3FYVX 3NZ6X 1DDSA 4DFRA 3HBBA 3IX9A 1DYIA 1M78A 3F0XX 3L3RA 4DP3A 5DXVA 1RA2A 1CZ3A 1DHFA 1U72A 1RX2A 2W9TA 1RX6A 1M7AA 2CD2A 3K2HA 2W3BA 3FYWX 3FQVA 1DG5A 3OCHA 3SA1A 1RA3A 1KMSA 3FQ0A 1DLRA 2DRCA 1DR5A 3INVA 4IXGX 3SRUX 1ZDRA 1DRAA 3KJRA 4XT7A 3NZBX 4HA7A 1RE7A 3SRRX 3NRRA 2KGKA 1J3KA 3QL0A 3FS6A 2BLCA 3JVXA 4DPHA 2ZZAA 2H2QA 4KM2A 4KNEA 3SRSX 3JW3A 3GYFA 3UM5A 4XRBA 5HVBA 5HUIA 5JG0X 3DGAA 5HQYA 1MVTA 4KM0A 4QJZD 3FY8X 1PD9A 3KY8A 3F0QX 5HT5A 4X5FA 2GD9A 3NXVA 3M08A 2AZNA 3SRWX 1OHJA 3DFRA 3TQBA 3FQCA 3KJSA 1U70A 3HJ3A 3JWMA 1AO8A 3Q1HA 4ELGA 1RG7A 3SAIA 4QHVA 4M2XA 3GHVA 5HSUA 1AI9A 4QI9A 1LY3A 3OAFA 4KL9A 4H97A 2LF1A 3QYOA 2W9SA 3RO9A 4KFJA 3F0SX 3JSUA 1DYHA 4LAHX 5U26A 4Q6AA 4G95A 3CL9A 3QFXA 2BL9A 1KLKA 4ELEA 3JWKA 1S3YA 5HVEA 5JA3A 3F8ZA 1OHKA 4Q0DA 1JUVA 4OR7A 2HM9A 3NZDA 7DFRA 5ECXA 3GI2A 4KAKA 3F8YA 4H98A 3QLXA 3DL5A 3R33A 4OSGA 1RH3A 4KEBA 4KY4A 3JWFA 1U71A 3IROA 3ROAA 4PSTA 3NXTA 4IXFX 4NX6A 3F0UX 4ELBA 1HFQA 1RX5A 4P66A 4HA9A 1DYJA 3NXOA 4P3RA 5HI6A 2C2TA 1IA4A 4M6JA 3EEKA 1LUDA 1RC4A 1VJ3A 4KD7A 4M7UA 1LY4A 1RX4A 3EX8A 3I3RA 1DLSA 2DHFA 2ANOA 3KGYA 3S9UA 5HT4A 3K47A 1HFPA 4QJCA 3K74A 4H95A 2FZJA 2OBCA 3TQ9A 4HOFA 4FGHA 2ANQA 3FRDX 3QLSA 2HQPA 2B3ZA 4X5JA 4FGGA 2BLBA 4X5IA 1QZFA 2FZHA 1RA8A 1RB3A 2W9GA 3FRBX 4ELFA 4FHBA 4NX7A 4XT6A 4KLXA 1BZFA 5HSRA 4DPDA 1J3JA 2XW7A 3FQFA 3F0BX 3SR5X 6DFRA 2W3VA 3NZAX 3QYLA 5CCCA 3TQAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF7 A;  3EEJ A;  1DR7 A;  4H96 A;  1DR2 A;  3KFY A;  3FQZ A;  4HOE A;  3D80 A;  3IA4 A;  2JYB A;  2W9H A;  3RG9 A;  4P3Q A;  2W3M A;  4X5G A;  2O7P A;  4KY8 A;  4XT4 A;  4PSY A;  4XEC X;  3QL3 A;  3QG2 A;  4PSS A;  1DF7 A;  2CIG A;  3QLW A;  5HF2 X;  3LG4 A;  3IRN A;  3S7A A;  1MVS A;  2L28 A;  1DRB A;  4XT5 A;  1RB2 A;  2QK8 A;  3FRA X;  4M7V A;  1S3W A;  3CSE A;  2D0K A;  1RX7 A;  3GHC A;  3QLR A;  1J3I A;  5HQZ A;  3ZPG A;  5FDA A;  3QGT A;  1RX3 A;  3FRF X;  1KMV A;  4KBN A;  1DHJ A;  3FY9 X;  4TU5 X;  4KJJ A;  1IA1 A;  4QLE A;  3S3V A;  4LAE X;  4I13 A;  2BLA A;  2W3A A;  1SEJ A;  4EIZ A;  1RX8 A;  3IA5 A;  2ITH A;  2D5N A;  3SQY X;  4ELH A;  5EAJ A;  4M6L A;  1IA2 A;  1D1G A;  3UM8 A;  4EIL A;  5HPB A;  1VDR A;  3F91 A;  3JW5 A;  3NXX A;  3CD2 A;  3FL8 A;  3DAT A;  3SA2 A;  1DR4 A;  8DFR A;  1AOE A;  4EJ1 A;  3EIG A;  1PDB A;  1PD8 A;  3D84 X;  3DAU A;  3GHW A;  2G6V A;  3JTW A;  2P4G A;  1DRF A;  3IRM A;  4QLF A;  4GH8 A;  2C2S A;  3FQO A;  4KJK A;  4LEK X;  5DFR A;  3UM6 A;  5E8Q A;  4Q0E A;  4PTH A;  2INQ A;  1JOL A;  4P68 A;  2OIP A;  3QLY A;  4I1N A;  1DR3 A;  3DRC A;  1E26 A;  3E0B A;  4DDR A;  4HOG A;  2W3W A;  3I8A X;  1TDR A;  1S3U A;  4LAG X;  1DG8 A;  4G8Z X;  3TD8 A;  1HFR A;  4KJL A;  1RA9 A;  2HXV A;  4IXE D;  1DIU A;  4XE6 X;  5CC9 A;  3NXR A;  3K45 A;  1DIS A;  3FRE X;  4QLG A;  4Q67 A;  5ECC A;  1DYR A;  1JOM A;  3CLB A;  1IA3 A;  1DAJ A;  1DRE A;  3DL6 A;  1S3V A;  3FL9 A;  1RX1 A;  3JWC A;  4PTJ A;  5HF0 X;  3NZC X;  1DR1 A;  1DG7 A;  3SGY A;  4G3M A;  1YHO A;  3SRQ X;  1CD2 A;  1DHI A;  4XT8 A;  1M79 A;  1RD7 A;  1DR6 A;  4KYA A;  3EEM A;  3VCO A;  3NU0 A;  1DRH A;  4CD2 A;  3EEL A;  4PDJ A;  3N0H A;  2FZI A;  3F0V X;  4RGC A;  5U27 A;  4EIG A;  4M6K A;  3ZPC A;  3TQ8 A;  3QLZ A;  1DDR A;  3NTZ A;  4ECK A;  1RA1 A;  4X5H A;  3NZ9 X;  3M09 A;  3SH2 A;  1BOZ A;  1RX9 A;  3DG8 A;  3NXY A;  3FYV X;  3NZ6 X;  1DDS A;  4DFR A;  3HBB A;  3IX9 A;  1DYI A;  1M78 A;  3F0X X;  3L3R A;  4DP3 A;  5DXV A;  1RA2 A;  1CZ3 A;  1DHF A;  1U72 A;  1RX2 A;  2W9T A;  1RX6 A;  1M7A A;  2CD2 A;  3K2H A;  2W3B A;  3FYW X;  3FQV A;  1DG5 A;  3OCH A;  3SA1 A;  1RA3 A;  1KMS A;  3FQ0 A;  1DLR A;  2DRC A;  1DR5 A;  3INV A;  4IXG X;  3SRU X;  1ZDR A;  1DRA A;  3KJR A;  4XT7 A;  3NZB X;  4HA7 A;  1RE7 A;  3SRR X;  3NRR A;  2KGK A;  1J3K A;  3QL0 A;  3FS6 A;  2BLC A;  3JVX A;  4DPH A;  2ZZA A;  2H2Q A;  4KM2 A;  4KNE A;  3SRS X;  3JW3 A;  3GYF A;  3UM5 A;  4XRB A;  5HVB A;  5HUI A;  5JG0 X;  3DGA A;  5HQY A;  1MVT A;  4KM0 A;  4QJZ D;  3FY8 X;  1PD9 A;  3KY8 A;  3F0Q X;  5HT5 A;  4X5F A;  2GD9 A;  3NXV A;  3M08 A;  2AZN A;  3SRW X;  1OHJ A;  3DFR A;  3TQB A;  3FQC A;  3KJS A;  1U70 A;  3HJ3 A;  3JWM A;  1AO8 A;  3Q1H A;  4ELG A;  1RG7 A;  3SAI A;  4QHV A;  4M2X A;  3GHV A;  5HSU A;  1AI9 A;  4QI9 A;  1LY3 A;  3OAF A;  4KL9 A;  4H97 A;  2LF1 A;  3QYO A;  2W9S A;  3RO9 A;  4KFJ A;  3F0S X;  3JSU A;  1DYH A;  4LAH X;  5U26 A;  4Q6A A;  4G95 A;  3CL9 A;  3QFX A;  2BL9 A;  1KLK A;  4ELE A;  3JWK A;  1S3Y A;  5HVE A;  5JA3 A;  3F8Z A;  1OHK A;  4Q0D A;  1JUV A;  4OR7 A;  2HM9 A;  3NZD A;  7DFR A;  5ECX A;  3GI2 A;  4KAK A;  3F8Y A;  4H98 A;  3QLX A;  3DL5 A;  3R33 A;  4OSG A;  1RH3 A;  4KEB A;  4KY4 A;  3JWF A;  1U71 A;  3IRO A;  3ROA A;  4PST A;  3NXT A;  4IXF X;  4NX6 A;  3F0U X;  4ELB A;  1HFQ A;  1RX5 A;  4P66 A;  4HA9 A;  1DYJ A;  3NXO A;  4P3R A;  5HI6 A;  2C2T A;  1IA4 A;  4M6J A;  3EEK A;  1LUD A;  1RC4 A;  1VJ3 A;  4KD7 A;  4M7U A;  1LY4 A;  1RX4 A;  3EX8 A;  3I3R A;  1DLS A;  2DHF A;  2ANO A;  3KGY A;  3S9U A;  5HT4 A;  3K47 A;  1HFP A;  4QJC A;  3K74 A;  4H95 A;  2FZJ A;  2OBC A;  3TQ9 A;  4HOF A;  4FGH A;  2ANQ A;  3FRD X;  3QLS A;  2HQP A;  2B3Z A;  4X5J A;  4FGG A;  2BLB A;  4X5I A;  1QZF A;  2FZH A;  1RA8 A;  1RB3 A;  2W9G A;  3FRB X;  4ELF A;  4FHB A;  4NX7 A;  4XT6 A;  4KLX A;  1BZF A;  5HSR A;  4DPD A;  1J3J A;  2XW7 A;  3FQF A;  3F0B X;  3SR5 X;  6DFR A;  2W3V A;  3NZA X;  3QYL A;  5CCC A;  3TQA A; 
#chains in the Genus database with same CATH topology
 1RF7 A;  3EEJ A;  1DR7 A;  4H96 A;  1DR2 A;  3KFY A;  3FQZ A;  4HOE A;  3D80 A;  3IA4 A;  2JYB A;  2W9H A;  3RG9 A;  4P3Q A;  2W3M A;  4X5G A;  2O7P A;  4KY8 A;  4XT4 A;  4PSY A;  4XEC X;  3QL3 A;  3QG2 A;  4PSS A;  1DF7 A;  2CIG A;  3QLW A;  5HF2 X;  3LG4 A;  3IRN A;  3S7A A;  1MVS A;  2L28 A;  1DRB A;  4XT5 A;  1RB2 A;  2QK8 A;  3FRA X;  4M7V A;  1S3W A;  3CSE A;  2D0K A;  1RX7 A;  3GHC A;  3QLR A;  1J3I A;  5HQZ A;  3ZPG A;  5FDA A;  3QGT A;  1RX3 A;  3FRF X;  1KMV A;  4KBN A;  1DHJ A;  3FY9 X;  4TU5 X;  4KJJ A;  1IA1 A;  4QLE A;  3S3V A;  4LAE X;  4I13 A;  2BLA A;  2W3A A;  1SEJ A;  4EIZ A;  1RX8 A;  3IA5 A;  2ITH A;  2D5N A;  3SQY X;  4ELH A;  5EAJ A;  4M6L A;  1IA2 A;  1D1G A;  3UM8 A;  4EIL A;  5HPB A;  1VDR A;  3F91 A;  3JW5 A;  3NXX A;  3CD2 A;  3FL8 A;  3DAT A;  3SA2 A;  1DR4 A;  8DFR A;  1AOE A;  4EJ1 A;  3EIG A;  1PDB A;  1PD8 A;  3D84 X;  3DAU A;  3GHW A;  2G6V A;  3JTW A;  2P4G A;  1DRF A;  3IRM A;  4QLF A;  4GH8 A;  2C2S A;  3FQO A;  4KJK A;  4LEK X;  5DFR A;  3UM6 A;  5E8Q A;  4Q0E A;  4PTH A;  2INQ A;  1JOL A;  4P68 A;  2OIP A;  3QLY A;  4I1N A;  1DR3 A;  3DRC A;  1E26 A;  3E0B A;  4DDR A;  4HOG A;  2W3W A;  3I8A X;  1TDR A;  1S3U A;  4LAG X;  1DG8 A;  4G8Z X;  3TD8 A;  1HFR A;  4KJL A;  1RA9 A;  2HXV A;  4IXE D;  1DIU A;  4XE6 X;  5CC9 A;  3NXR A;  3K45 A;  1DIS A;  3FRE X;  4QLG A;  4Q67 A;  5ECC A;  1DYR A;  1JOM A;  3CLB A;  1IA3 A;  1DAJ A;  1DRE A;  3DL6 A;  1S3V A;  3FL9 A;  1RX1 A;  3JWC A;  4PTJ A;  5HF0 X;  3NZC X;  1DR1 A;  1DG7 A;  3SGY A;  4G3M A;  1YHO A;  3SRQ X;  1CD2 A;  1DHI A;  4XT8 A;  1M79 A;  1RD7 A;  1DR6 A;  4KYA A;  3EEM A;  3VCO A;  3NU0 A;  1DRH A;  4CD2 A;  3EEL A;  4PDJ A;  3N0H A;  2FZI A;  3F0V X;  4RGC A;  5U27 A;  4EIG A;  4M6K A;  3ZPC A;  3TQ8 A;  3QLZ A;  1DDR A;  3NTZ A;  4ECK A;  1RA1 A;  4X5H A;  3NZ9 X;  3M09 A;  3SH2 A;  1BOZ A;  1RX9 A;  3DG8 A;  3NXY A;  3FYV X;  3NZ6 X;  1DDS A;  4DFR A;  3HBB A;  3IX9 A;  1DYI A;  1M78 A;  3F0X X;  3L3R A;  4DP3 A;  5DXV A;  1RA2 A;  1CZ3 A;  1DHF A;  1U72 A;  1RX2 A;  2W9T A;  1RX6 A;  1M7A A;  2CD2 A;  3K2H A;  2W3B A;  3FYW X;  3FQV A;  1DG5 A;  3OCH A;  3SA1 A;  1RA3 A;  1KMS A;  3FQ0 A;  1DLR A;  2DRC A;  1DR5 A;  3INV A;  4IXG X;  3SRU X;  1ZDR A;  1DRA A;  3KJR A;  4XT7 A;  3NZB X;  4HA7 A;  1RE7 A;  3SRR X;  3NRR A;  2KGK A;  1J3K A;  3QL0 A;  3FS6 A;  2BLC A;  3JVX A;  4DPH A;  2ZZA A;  2H2Q A;  4KM2 A;  4KNE A;  3SRS X;  3JW3 A;  3GYF A;  3UM5 A;  4XRB A;  5HVB A;  5HUI A;  5JG0 X;  3DGA A;  5HQY A;  1MVT A;  4KM0 A;  4QJZ D;  3FY8 X;  1PD9 A;  3KY8 A;  3F0Q X;  5HT5 A;  4X5F A;  2GD9 A;  3NXV A;  3M08 A;  2AZN A;  3SRW X;  1OHJ A;  3DFR A;  3TQB A;  3FQC A;  3KJS A;  1U70 A;  3HJ3 A;  3JWM A;  1AO8 A;  3Q1H A;  4ELG A;  1RG7 A;  3SAI A;  4QHV A;  4M2X A;  3GHV A;  5HSU A;  1AI9 A;  4QI9 A;  1LY3 A;  3OAF A;  4KL9 A;  4H97 A;  2LF1 A;  3QYO A;  2W9S A;  3RO9 A;  4KFJ A;  3F0S X;  3JSU A;  1DYH A;  4LAH X;  5U26 A;  4Q6A A;  4G95 A;  3CL9 A;  3QFX A;  2BL9 A;  1KLK A;  4ELE A;  3JWK A;  1S3Y A;  5HVE A;  5JA3 A;  3F8Z A;  1OHK A;  4Q0D A;  1JUV A;  4OR7 A;  2HM9 A;  3NZD A;  7DFR A;  5ECX A;  3GI2 A;  4KAK A;  3F8Y A;  4H98 A;  3QLX A;  3DL5 A;  3R33 A;  4OSG A;  1RH3 A;  4KEB A;  4KY4 A;  3JWF A;  1U71 A;  3IRO A;  3ROA A;  4PST A;  3NXT A;  4IXF X;  4NX6 A;  3F0U X;  4ELB A;  1HFQ A;  1RX5 A;  4P66 A;  4HA9 A;  1DYJ A;  3NXO A;  4P3R A;  5HI6 A;  2C2T A;  1IA4 A;  4M6J A;  3EEK A;  1LUD A;  1RC4 A;  1VJ3 A;  4KD7 A;  4M7U A;  1LY4 A;  1RX4 A;  3EX8 A;  3I3R A;  1DLS A;  2DHF A;  2ANO A;  3KGY A;  3S9U A;  5HT4 A;  3K47 A;  1HFP A;  4QJC A;  3K74 A;  4H95 A;  2FZJ A;  2OBC A;  3TQ9 A;  4HOF A;  4FGH A;  2ANQ A;  3FRD X;  3QLS A;  2HQP A;  2B3Z A;  4X5J A;  4FGG A;  2BLB A;  4X5I A;  1QZF A;  2FZH A;  1RA8 A;  1RB3 A;  2W9G A;  3FRB X;  4ELF A;  4FHB A;  4NX7 A;  4XT6 A;  4KLX A;  1BZF A;  5HSR A;  4DPD A;  1J3J A;  2XW7 A;  3FQF A;  3F0B X;  3SR5 X;  6DFR A;  2W3V A;  3NZA X;  3QYL A;  5CCC A;  3TQA A; 
#chains in the Genus database with same CATH homology
 1RF7 A;  3EEJ A;  1DR7 A;  4H96 A;  1DR2 A;  3KFY A;  3FQZ A;  4HOE A;  3D80 A;  3IA4 A;  2JYB A;  2W9H A;  3RG9 A;  4P3Q A;  2W3M A;  4X5G A;  2O7P A;  4KY8 A;  4XT4 A;  4PSY A;  4XEC X;  3QL3 A;  3QG2 A;  4PSS A;  1DF7 A;  2CIG A;  3QLW A;  5HF2 X;  3LG4 A;  3IRN A;  3S7A A;  1MVS A;  2L28 A;  1DRB A;  4XT5 A;  1RB2 A;  2QK8 A;  3FRA X;  4M7V A;  1S3W A;  3CSE A;  2D0K A;  1RX7 A;  3GHC A;  3QLR A;  1J3I A;  5HQZ A;  3ZPG A;  5FDA A;  3QGT A;  1RX3 A;  3FRF X;  1KMV A;  4KBN A;  1DHJ A;  3FY9 X;  4TU5 X;  4KJJ A;  1IA1 A;  4QLE A;  3S3V A;  4LAE X;  4I13 A;  2BLA A;  2W3A A;  1SEJ A;  4EIZ A;  1RX8 A;  3IA5 A;  2ITH A;  2D5N A;  3SQY X;  4ELH A;  5EAJ A;  4M6L A;  1IA2 A;  1D1G A;  3UM8 A;  4EIL A;  5HPB A;  1VDR A;  3F91 A;  3JW5 A;  3NXX A;  3CD2 A;  3FL8 A;  3DAT A;  3SA2 A;  1DR4 A;  8DFR A;  1AOE A;  4EJ1 A;  3EIG A;  1PDB A;  1PD8 A;  3D84 X;  3DAU A;  3GHW A;  2G6V A;  3JTW A;  2P4G A;  1DRF A;  3IRM A;  4QLF A;  4GH8 A;  2C2S A;  3FQO A;  4KJK A;  4LEK X;  5DFR A;  3UM6 A;  5E8Q A;  4Q0E A;  4PTH A;  2INQ A;  1JOL A;  4P68 A;  2OIP A;  3QLY A;  4I1N A;  1DR3 A;  3DRC A;  1E26 A;  3E0B A;  4DDR A;  4HOG A;  2W3W A;  3I8A X;  1TDR A;  1S3U A;  4LAG X;  1DG8 A;  4G8Z X;  3TD8 A;  1HFR A;  4KJL A;  1RA9 A;  2HXV A;  4IXE D;  1DIU A;  4XE6 X;  5CC9 A;  3NXR A;  3K45 A;  1DIS A;  3FRE X;  4QLG A;  4Q67 A;  5ECC A;  1DYR A;  1JOM A;  3CLB A;  1IA3 A;  1DAJ A;  1DRE A;  3DL6 A;  1S3V A;  3FL9 A;  1RX1 A;  3JWC A;  4PTJ A;  5HF0 X;  3NZC X;  1DR1 A;  1DG7 A;  3SGY A;  4G3M A;  1YHO A;  3SRQ X;  1CD2 A;  1DHI A;  4XT8 A;  1M79 A;  1RD7 A;  1DR6 A;  4KYA A;  3EEM A;  3VCO A;  3NU0 A;  1DRH A;  4CD2 A;  3EEL A;  4PDJ A;  3N0H A;  2FZI A;  3F0V X;  4RGC A;  5U27 A;  4EIG A;  4M6K A;  3ZPC A;  3TQ8 A;  3QLZ A;  1DDR A;  3NTZ A;  4ECK A;  1RA1 A;  4X5H A;  3NZ9 X;  3M09 A;  3SH2 A;  1BOZ A;  1RX9 A;  3DG8 A;  3NXY A;  3FYV X;  3NZ6 X;  1DDS A;  4DFR A;  3HBB A;  3IX9 A;  1DYI A;  1M78 A;  3F0X X;  3L3R A;  4DP3 A;  5DXV A;  1RA2 A;  1CZ3 A;  1DHF A;  1U72 A;  1RX2 A;  2W9T A;  1RX6 A;  1M7A A;  2CD2 A;  3K2H A;  2W3B A;  3FYW X;  3FQV A;  1DG5 A;  3OCH A;  3SA1 A;  1RA3 A;  1KMS A;  3FQ0 A;  1DLR A;  2DRC A;  1DR5 A;  3INV A;  4IXG X;  3SRU X;  1ZDR A;  1DRA A;  3KJR A;  4XT7 A;  3NZB X;  4HA7 A;  1RE7 A;  3SRR X;  3NRR A;  2KGK A;  1J3K A;  3QL0 A;  3FS6 A;  2BLC A;  3JVX A;  4DPH A;  2ZZA A;  2H2Q A;  4KM2 A;  4KNE A;  3SRS X;  3JW3 A;  3GYF A;  3UM5 A;  4XRB A;  5HVB A;  5HUI A;  5JG0 X;  3DGA A;  5HQY A;  1MVT A;  4KM0 A;  4QJZ D;  3FY8 X;  1PD9 A;  3KY8 A;  3F0Q X;  5HT5 A;  4X5F A;  2GD9 A;  3NXV A;  3M08 A;  2AZN A;  3SRW X;  1OHJ A;  3DFR A;  3TQB A;  3FQC A;  3KJS A;  1U70 A;  3HJ3 A;  3JWM A;  1AO8 A;  3Q1H A;  4ELG A;  1RG7 A;  3SAI A;  4QHV A;  4M2X A;  3GHV A;  5HSU A;  1AI9 A;  4QI9 A;  1LY3 A;  3OAF A;  4KL9 A;  4H97 A;  2LF1 A;  3QYO A;  2W9S A;  3RO9 A;  4KFJ A;  3F0S X;  3JSU A;  1DYH A;  4LAH X;  5U26 A;  4Q6A A;  4G95 A;  3CL9 A;  3QFX A;  2BL9 A;  1KLK A;  4ELE A;  3JWK A;  1S3Y A;  5HVE A;  5JA3 A;  3F8Z A;  1OHK A;  4Q0D A;  1JUV A;  4OR7 A;  2HM9 A;  3NZD A;  7DFR A;  5ECX A;  3GI2 A;  4KAK A;  3F8Y A;  4H98 A;  3QLX A;  3DL5 A;  3R33 A;  4OSG A;  1RH3 A;  4KEB A;  4KY4 A;  3JWF A;  1U71 A;  3IRO A;  3ROA A;  4PST A;  3NXT A;  4IXF X;  4NX6 A;  3F0U X;  4ELB A;  1HFQ A;  1RX5 A;  4P66 A;  4HA9 A;  1DYJ A;  3NXO A;  4P3R A;  5HI6 A;  2C2T A;  1IA4 A;  4M6J A;  3EEK A;  1LUD A;  1RC4 A;  1VJ3 A;  4KD7 A;  4M7U A;  1LY4 A;  1RX4 A;  3EX8 A;  3I3R A;  1DLS A;  2DHF A;  2ANO A;  3KGY A;  3S9U A;  5HT4 A;  3K47 A;  1HFP A;  4QJC A;  3K74 A;  4H95 A;  2FZJ A;  2OBC A;  3TQ9 A;  4HOF A;  4FGH A;  2ANQ A;  3FRD X;  3QLS A;  2HQP A;  2B3Z A;  4X5J A;  4FGG A;  2BLB A;  4X5I A;  1QZF A;  2FZH A;  1RA8 A;  1RB3 A;  2W9G A;  3FRB X;  4ELF A;  4FHB A;  4NX7 A;  4XT6 A;  4KLX A;  1BZF A;  5HSR A;  4DPD A;  1J3J A;  2XW7 A;  3FQF A;  3F0B X;  3SR5 X;  6DFR A;  2W3V A;  3NZA X;  3QYL A;  5CCC A;  3TQA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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