1DYJA

Isomorphous crystal structures of escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate and 5,10-dideazatetrahydrofolate: mechanistic implications
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 43
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1994-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1dyjA00
1RX8A 3GHWA 4HOGA 4M7VA 5U26A 1DG8A 4ELHA 4Q0EA 4Q67A 1DR3A 2W9TA 2W3MA 2W3VA 1RA9A 1J3IA 3N0HA 1OHJA 3DL5A 2KGKA 3NZ9X 4XT6A 4M2XA 3QGTA 3IRMA 3S3VA 3SA1A 4KLXA 3SQYX 5EAJA 3K47A 4GH8A 1MVTA 2HQPA 3QLWA 3FRAX 3GI2A 3EX8A 3HJ3A 4KY4A 3CL9A 1DYJA 4QHVA 1BZFA 4ELBA 3QLZA 1AO8A 1RX2A 1LY4A 3F8YA 4ELFA 3FQFA 3DGAA 7DFRA 1QZFA 4KBNA 4QI9A 3VCOA 3F0XX 1RA2A 4G95A 4M6KA 8DFRA 4X5JA 3KJRA 2OIPA 4XT7A 2ANQA 3SRQX 4KEBA 4P68A 5HF2X 2DRCA 2GD9A 6DFRA 1DLRA 4IXFX 3SH2A 1DF7A 4HA7A 3CD2A 1ZDRA 2ANOA 2W3WA 2B3ZA 3NXYA 5DXVA 3EEJA 3UM5A 4EJ1A 3F0QX 1RX4A 3FQ0A 3HBBA 1RX1A 3FRFX 1M78A 4LAGX 4KNEA 4KD7A 1PD9A 5E8QA 1RA8A 4P66A 1S3YA 3EEKA 3IA5A 3L3RA 1DDSA 2BLAA 2D5NA 1JOLA 4I1NA 5HT5A 2ZZAA 2W9GA 3QLRA 3DATA 1IA4A 3FL9A 4QLGA 1IA3A 4XT5A 1LUDA 4LAEX 5FDAA 3FY8X 1PDBA 4FGHA 5HPBA 3JWFA 3QLYA 1RA3A 3JVXA 3DRCA 3DG8A 1PD8A 3QFXA 1TDRA 3TQBA 3UM6A 1DRHA 1RC4A 1BOZA 3I3RA 3KJSA 3FS6A 4XRBA 1M79A 3S9UA 5JA3A 4ECKA 1HFQA 1KMVA 4KAKA 1DDRA 4M6JA 1DR4A 3I8AX 4NX7A 1DREA 1DHFA 3D84X 4LEKX 4HOEA 3DAUA 5HQYA 4IXED 1U71A 1DISA 4PSSA 1JUVA 3NZDA 1DAJA 2FZIA 1RE7A 3QYOA 1MVSA 1RB2A 3KFYA 2W3BA 3QLXA 1DRFA 3FYVX 3K45A 3KGYA 3RO9A 1RA1A 3QL3A 1DYIA 1DHIA 2LF1A 3FRDX 1DRBA 3QL0A 1RD7A 1LY3A 1IA1A 2AZNA 4P3RA 4KJLA 3SRSX 3FREX 3JTWA 3NU0A 3FQCA 4X5HA 4KM2A 1RX6A 5JG0X 3F8ZA 5ECCA 2CIGA 3TQ8A 1KMSA 3GHVA 5HF0X 3ROAA 3ZPGA 2W9HA 4Q0DA 1E26A 1RX9A 1S3VA 2P4GA 3FYWX 5HT4A 2INQA 3FY9X 1J3KA 3GHCA 1M7AA 3F0UX 3JWKA 3NXTA 1IA2A 2C2TA 3FRBX 3S7AA 1J3JA 3F91A 3M08A 3JWCA 3JW5A 1S3UA 3IRNA 4DP3A 3SAIA 3IX9A 4PSYA 4XECX 4KFJA 1JOMA 1DR1A 3NTZA 3TQ9A 3SA2A 4PTJA 2BLCA 4DPDA 1DR7A 4XE6X 4H97A 3DFRA 3IA4A 1HFPA 1RG7A 3F0SX 3M09A 4HOFA 4EILA 1DR2A 1CD2A 1DYHA 4EIGA 4EIZA 4IXGX 3EEMA 4PSTA 1DR5A 2JYBA 4OR7A 4CD2A 4RGCA 1RH3A 4XT8A 4H98A 5CCCA 1U72A 3NXRA 1AI9A 4KYAA 4M7UA 5HQZA 3D80A 4QJCA 1DLSA 3NZ6X 3Q1HA 1VJ3A 3SRWX 1RF7A 1RX5A 4FGGA 3F0VX 4OSGA 1KLKA 1RX7A 1DIUA 2XW7A 3EIGA 4DDRA 3OAFA 2QK8A 1DRAA 3QYLA 2HM9A 1D1GA 4G8ZX 3K2HA 4DPHA 3SRUX 2L28A 4PDJA 1SEJA 2W3AA 1DG5A 1RX3A 3TQAA 2FZHA 5DFRA 1DHJA 1DYRA 4TU5X 2DHFA 2G6VA 5U27A 4X5FA 4KJJA 1YHOA 3F0BX 4FHBA 3FQZA 3E0BA 3ZPCA 5HSUA 2C2SA 2O7PA 3TD8A 5HVEA 4PTHA 3JWMA 4X5GA 1DR6A 3FQVA 4I13A 4KM0A 4QLEA 2OBCA 4X5IA 4NX6A 3R33A 1U70A 4DFRA 3SRRX 3CLBA 3QG2A 2D0KA 3NZAX 1OHKA 5ECXA 2ITHA 3RG9A 1DG7A 1AOEA 3SGYA 1S3WA 4HA9A 3EELA 3NXOA 5CC9A 4H96A 2BL9A 3GYFA 4ELGA 3OCHA 4QLFA 3DL6A 3JW3A 3FQOA 1RB3A 3INVA 4XT4A 3IROA 4G3MA 5HUIA 3FL8A 3NZCX 2HXVA 3UM8A 4KY8A 3JSUA 3KY8A 2W9SA 4Q6AA 3CSEA 3QLSA 3NZBX 2FZJA 3NXXA 4M6LA 4QJZD 2H2QA 2CD2A 4ELEA 2BLBA 3LG4A 4H95A 5HVBA 4P3QA 3SR5X 1CZ3A 5HI6A 3NRRA 3K74A 5HSRA 4KJKA 1VDRA 3NXVA 4KL9A 1HFRA 4LAHX
chains in the Genus database with same CATH superfamily
1RX8A 3GHWA 4HOGA 4M7VA 5U26A 1DG8A 4ELHA 4Q0EA 4Q67A 1DR3A 2W9TA 2W3MA 2W3VA 1RA9A 1J3IA 3N0HA 1OHJA 3DL5A 2KGKA 3NZ9X 4XT6A 4M2XA 3QGTA 3IRMA 3S3VA 3SA1A 4KLXA 3SQYX 5EAJA 3K47A 4GH8A 1MVTA 2HQPA 3QLWA 3FRAX 3GI2A 3EX8A 3HJ3A 4KY4A 3CL9A 1DYJA 4QHVA 1BZFA 4ELBA 3QLZA 1AO8A 1RX2A 1LY4A 3F8YA 4ELFA 3FQFA 3DGAA 7DFRA 1QZFA 4KBNA 4QI9A 3VCOA 3F0XX 1RA2A 4G95A 4M6KA 8DFRA 4X5JA 3KJRA 2OIPA 4XT7A 2ANQA 3SRQX 4KEBA 4P68A 5HF2X 2DRCA 2GD9A 6DFRA 1DLRA 4IXFX 3SH2A 1DF7A 4HA7A 3CD2A 1ZDRA 2ANOA 2W3WA 2B3ZA 3NXYA 5DXVA 3EEJA 3UM5A 4EJ1A 3F0QX 1RX4A 3FQ0A 3HBBA 1RX1A 3FRFX 1M78A 4LAGX 4KNEA 4KD7A 1PD9A 5E8QA 1RA8A 4P66A 1S3YA 3EEKA 3IA5A 3L3RA 1DDSA 2BLAA 2D5NA 1JOLA 4I1NA 5HT5A 2ZZAA 2W9GA 3QLRA 3DATA 1IA4A 3FL9A 4QLGA 1IA3A 4XT5A 1LUDA 4LAEX 5FDAA 3FY8X 1PDBA 4FGHA 5HPBA 3JWFA 3QLYA 1RA3A 3JVXA 3DRCA 3DG8A 1PD8A 3QFXA 1TDRA 3TQBA 3UM6A 1DRHA 1RC4A 1BOZA 3I3RA 3KJSA 3FS6A 4XRBA 1M79A 3S9UA 5JA3A 4ECKA 1HFQA 1KMVA 4KAKA 1DDRA 4M6JA 1DR4A 3I8AX 4NX7A 1DREA 1DHFA 3D84X 4LEKX 4HOEA 3DAUA 5HQYA 4IXED 1U71A 1DISA 4PSSA 1JUVA 3NZDA 1DAJA 2FZIA 1RE7A 3QYOA 1MVSA 1RB2A 3KFYA 2W3BA 3QLXA 1DRFA 3FYVX 3K45A 3KGYA 3RO9A 1RA1A 3QL3A 1DYIA 1DHIA 2LF1A 3FRDX 1DRBA 3QL0A 1RD7A 1LY3A 1IA1A 2AZNA 4P3RA 4KJLA 3SRSX 3FREX 3JTWA 3NU0A 3FQCA 4X5HA 4KM2A 1RX6A 5JG0X 3F8ZA 5ECCA 2CIGA 3TQ8A 1KMSA 3GHVA 5HF0X 3ROAA 3ZPGA 2W9HA 4Q0DA 1E26A 1RX9A 1S3VA 2P4GA 3FYWX 5HT4A 2INQA 3FY9X 1J3KA 3GHCA 1M7AA 3F0UX 3JWKA 3NXTA 1IA2A 2C2TA 3FRBX 3S7AA 1J3JA 3F91A 3M08A 3JWCA 3JW5A 1S3UA 3IRNA 4DP3A 3SAIA 3IX9A 4PSYA 4XECX 4KFJA 1JOMA 1DR1A 3NTZA 3TQ9A 3SA2A 4PTJA 2BLCA 4DPDA 1DR7A 4XE6X 4H97A 3DFRA 3IA4A 1HFPA 1RG7A 3F0SX 3M09A 4HOFA 4EILA 1DR2A 1CD2A 1DYHA 4EIGA 4EIZA 4IXGX 3EEMA 4PSTA 1DR5A 2JYBA 4OR7A 4CD2A 4RGCA 1RH3A 4XT8A 4H98A 5CCCA 1U72A 3NXRA 1AI9A 4KYAA 4M7UA 5HQZA 3D80A 4QJCA 1DLSA 3NZ6X 3Q1HA 1VJ3A 3SRWX 1RF7A 1RX5A 4FGGA 3F0VX 4OSGA 1KLKA 1RX7A 1DIUA 2XW7A 3EIGA 4DDRA 3OAFA 2QK8A 1DRAA 3QYLA 2HM9A 1D1GA 4G8ZX 3K2HA 4DPHA 3SRUX 2L28A 4PDJA 1SEJA 2W3AA 1DG5A 1RX3A 3TQAA 2FZHA 5DFRA 1DHJA 1DYRA 4TU5X 2DHFA 2G6VA 5U27A 4X5FA 4KJJA 1YHOA 3F0BX 4FHBA 3FQZA 3E0BA 3ZPCA 5HSUA 2C2SA 2O7PA 3TD8A 5HVEA 4PTHA 3JWMA 4X5GA 1DR6A 3FQVA 4I13A 4KM0A 4QLEA 2OBCA 4X5IA 4NX6A 3R33A 1U70A 4DFRA 3SRRX 3CLBA 3QG2A 2D0KA 3NZAX 1OHKA 5ECXA 2ITHA 3RG9A 1DG7A 1AOEA 3SGYA 1S3WA 4HA9A 3EELA 3NXOA 5CC9A 4H96A 2BL9A 3GYFA 4ELGA 3OCHA 4QLFA 3DL6A 3JW3A 3FQOA 1RB3A 3INVA 4XT4A 3IROA 4G3MA 5HUIA 3FL8A 3NZCX 2HXVA 3UM8A 4KY8A 3JSUA 3KY8A 2W9SA 4Q6AA 3CSEA 3QLSA 3NZBX 2FZJA 3NXXA 4M6LA 4QJZD 2H2QA 2CD2A 4ELEA 2BLBA 3LG4A 4H95A 5HVBA 4P3QA 3SR5X 1CZ3A 5HI6A 3NRRA 3K74A 5HSRA 4KJKA 1VDRA 3NXVA 4KL9A 1HFRA 4LAHX
chains in the Genus database with same CATH topology
1RX8A 3GHWA 4HOGA 4M7VA 5U26A 1DG8A 4ELHA 4Q0EA 4Q67A 1DR3A 2W9TA 2W3MA 2W3VA 1RA9A 1J3IA 3N0HA 1OHJA 3DL5A 2KGKA 3NZ9X 4XT6A 4M2XA 3QGTA 3IRMA 3S3VA 3SA1A 4KLXA 3SQYX 5EAJA 3K47A 4GH8A 1MVTA 2HQPA 3QLWA 3FRAX 3GI2A 3EX8A 3HJ3A 4KY4A 3CL9A 1DYJA 4QHVA 1BZFA 4ELBA 3QLZA 1AO8A 1RX2A 1LY4A 3F8YA 4ELFA 3FQFA 3DGAA 7DFRA 1QZFA 4KBNA 4QI9A 3VCOA 3F0XX 1RA2A 4G95A 4M6KA 8DFRA 4X5JA 3KJRA 2OIPA 4XT7A 2ANQA 3SRQX 4KEBA 4P68A 5HF2X 2DRCA 2GD9A 6DFRA 1DLRA 4IXFX 3SH2A 1DF7A 4HA7A 3CD2A 1ZDRA 2ANOA 2W3WA 2B3ZA 3NXYA 5DXVA 3EEJA 3UM5A 4EJ1A 3F0QX 1RX4A 3FQ0A 3HBBA 1RX1A 3FRFX 1M78A 4LAGX 4KNEA 4KD7A 1PD9A 5E8QA 1RA8A 4P66A 1S3YA 3EEKA 3IA5A 3L3RA 1DDSA 2BLAA 2D5NA 1JOLA 4I1NA 5HT5A 2ZZAA 2W9GA 3QLRA 3DATA 1IA4A 3FL9A 4QLGA 1IA3A 4XT5A 1LUDA 4LAEX 5FDAA 3FY8X 1PDBA 4FGHA 5HPBA 3JWFA 3QLYA 1RA3A 3JVXA 3DRCA 3DG8A 1PD8A 3QFXA 1TDRA 3TQBA 3UM6A 1DRHA 1RC4A 1BOZA 3I3RA 3KJSA 3FS6A 4XRBA 1M79A 3S9UA 5JA3A 4ECKA 1HFQA 1KMVA 4KAKA 1DDRA 4M6JA 1DR4A 3I8AX 4NX7A 1DREA 1DHFA 3D84X 4LEKX 4HOEA 3DAUA 5HQYA 4IXED 1U71A 1DISA 4PSSA 1JUVA 3NZDA 1DAJA 2FZIA 1RE7A 3QYOA 1MVSA 1RB2A 3KFYA 2W3BA 3QLXA 1DRFA 3FYVX 3K45A 3KGYA 3RO9A 1RA1A 3QL3A 1DYIA 1DHIA 2LF1A 3FRDX 1DRBA 3QL0A 1RD7A 1LY3A 1IA1A 2AZNA 4P3RA 4KJLA 3SRSX 3FREX 3JTWA 3NU0A 3FQCA 4X5HA 4KM2A 1RX6A 5JG0X 3F8ZA 5ECCA 2CIGA 3TQ8A 1KMSA 3GHVA 5HF0X 3ROAA 3ZPGA 2W9HA 4Q0DA 1E26A 1RX9A 1S3VA 2P4GA 3FYWX 5HT4A 2INQA 3FY9X 1J3KA 3GHCA 1M7AA 3F0UX 3JWKA 3NXTA 1IA2A 2C2TA 3FRBX 3S7AA 1J3JA 3F91A 3M08A 3JWCA 3JW5A 1S3UA 3IRNA 4DP3A 3SAIA 3IX9A 4PSYA 4XECX 4KFJA 1JOMA 1DR1A 3NTZA 3TQ9A 3SA2A 4PTJA 2BLCA 4DPDA 1DR7A 4XE6X 4H97A 3DFRA 3IA4A 1HFPA 1RG7A 3F0SX 3M09A 4HOFA 4EILA 1DR2A 1CD2A 1DYHA 4EIGA 4EIZA 4IXGX 3EEMA 4PSTA 1DR5A 2JYBA 4OR7A 4CD2A 4RGCA 1RH3A 4XT8A 4H98A 5CCCA 1U72A 3NXRA 1AI9A 4KYAA 4M7UA 5HQZA 3D80A 4QJCA 1DLSA 3NZ6X 3Q1HA 1VJ3A 3SRWX 1RF7A 1RX5A 4FGGA 3F0VX 4OSGA 1KLKA 1RX7A 1DIUA 2XW7A 3EIGA 4DDRA 3OAFA 2QK8A 1DRAA 3QYLA 2HM9A 1D1GA 4G8ZX 3K2HA 4DPHA 3SRUX 2L28A 4PDJA 1SEJA 2W3AA 1DG5A 1RX3A 3TQAA 2FZHA 5DFRA 1DHJA 1DYRA 4TU5X 2DHFA 2G6VA 5U27A 4X5FA 4KJJA 1YHOA 3F0BX 4FHBA 3FQZA 3E0BA 3ZPCA 5HSUA 2C2SA 2O7PA 3TD8A 5HVEA 4PTHA 3JWMA 4X5GA 1DR6A 3FQVA 4I13A 4KM0A 4QLEA 2OBCA 4X5IA 4NX6A 3R33A 1U70A 4DFRA 3SRRX 3CLBA 3QG2A 2D0KA 3NZAX 1OHKA 5ECXA 2ITHA 3RG9A 1DG7A 1AOEA 3SGYA 1S3WA 4HA9A 3EELA 3NXOA 5CC9A 4H96A 2BL9A 3GYFA 4ELGA 3OCHA 4QLFA 3DL6A 3JW3A 3FQOA 1RB3A 3INVA 4XT4A 3IROA 4G3MA 5HUIA 3FL8A 3NZCX 2HXVA 3UM8A 4KY8A 3JSUA 3KY8A 2W9SA 4Q6AA 3CSEA 3QLSA 3NZBX 2FZJA 3NXXA 4M6LA 4QJZD 2H2QA 2CD2A 4ELEA 2BLBA 3LG4A 4H95A 5HVBA 4P3QA 3SR5X 1CZ3A 5HI6A 3NRRA 3K74A 5HSRA 4KJKA 1VDRA 3NXVA 4KL9A 1HFRA 4LAHX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RX8 A;  3GHW A;  4HOG A;  4M7V A;  5U26 A;  1DG8 A;  4ELH A;  4Q0E A;  4Q67 A;  1DR3 A;  2W9T A;  2W3M A;  2W3V A;  1RA9 A;  1J3I A;  3N0H A;  1OHJ A;  3DL5 A;  2KGK A;  3NZ9 X;  4XT6 A;  4M2X A;  3QGT A;  3IRM A;  3S3V A;  3SA1 A;  4KLX A;  3SQY X;  5EAJ A;  3K47 A;  4GH8 A;  1MVT A;  2HQP A;  3QLW A;  3FRA X;  3GI2 A;  3EX8 A;  3HJ3 A;  4KY4 A;  3CL9 A;  1DYJ A;  4QHV A;  1BZF A;  4ELB A;  3QLZ A;  1AO8 A;  1RX2 A;  1LY4 A;  3F8Y A;  4ELF A;  3FQF A;  3DGA A;  7DFR A;  1QZF A;  4KBN A;  4QI9 A;  3VCO A;  3F0X X;  1RA2 A;  4G95 A;  4M6K A;  8DFR A;  4X5J A;  3KJR A;  2OIP A;  4XT7 A;  2ANQ A;  3SRQ X;  4KEB A;  4P68 A;  5HF2 X;  2DRC A;  2GD9 A;  6DFR A;  1DLR A;  4IXF X;  3SH2 A;  1DF7 A;  4HA7 A;  3CD2 A;  1ZDR A;  2ANO A;  2W3W A;  2B3Z A;  3NXY A;  5DXV A;  3EEJ A;  3UM5 A;  4EJ1 A;  3F0Q X;  1RX4 A;  3FQ0 A;  3HBB A;  1RX1 A;  3FRF X;  1M78 A;  4LAG X;  4KNE A;  4KD7 A;  1PD9 A;  5E8Q A;  1RA8 A;  4P66 A;  1S3Y A;  3EEK A;  3IA5 A;  3L3R A;  1DDS A;  2BLA A;  2D5N A;  1JOL A;  4I1N A;  5HT5 A;  2ZZA A;  2W9G A;  3QLR A;  3DAT A;  1IA4 A;  3FL9 A;  4QLG A;  1IA3 A;  4XT5 A;  1LUD A;  4LAE X;  5FDA A;  3FY8 X;  1PDB A;  4FGH A;  5HPB A;  3JWF A;  3QLY A;  1RA3 A;  3JVX A;  3DRC A;  3DG8 A;  1PD8 A;  3QFX A;  1TDR A;  3TQB A;  3UM6 A;  1DRH A;  1RC4 A;  1BOZ A;  3I3R A;  3KJS A;  3FS6 A;  4XRB A;  1M79 A;  3S9U A;  5JA3 A;  4ECK A;  1HFQ A;  1KMV A;  4KAK A;  1DDR A;  4M6J A;  1DR4 A;  3I8A X;  4NX7 A;  1DRE A;  1DHF A;  3D84 X;  4LEK X;  4HOE A;  3DAU A;  5HQY A;  4IXE D;  1U71 A;  1DIS A;  4PSS A;  1JUV A;  3NZD A;  1DAJ A;  2FZI A;  1RE7 A;  3QYO A;  1MVS A;  1RB2 A;  3KFY A;  2W3B A;  3QLX A;  1DRF A;  3FYV X;  3K45 A;  3KGY A;  3RO9 A;  1RA1 A;  3QL3 A;  1DYI A;  1DHI A;  2LF1 A;  3FRD X;  1DRB A;  3QL0 A;  1RD7 A;  1LY3 A;  1IA1 A;  2AZN A;  4P3R A;  4KJL A;  3SRS X;  3FRE X;  3JTW A;  3NU0 A;  3FQC A;  4X5H A;  4KM2 A;  1RX6 A;  5JG0 X;  3F8Z A;  5ECC A;  2CIG A;  3TQ8 A;  1KMS A;  3GHV A;  5HF0 X;  3ROA A;  3ZPG A;  2W9H A;  4Q0D A;  1E26 A;  1RX9 A;  1S3V A;  2P4G A;  3FYW X;  5HT4 A;  2INQ A;  3FY9 X;  1J3K A;  3GHC A;  1M7A A;  3F0U X;  3JWK A;  3NXT A;  1IA2 A;  2C2T A;  3FRB X;  3S7A A;  1J3J A;  3F91 A;  3M08 A;  3JWC A;  3JW5 A;  1S3U A;  3IRN A;  4DP3 A;  3SAI A;  3IX9 A;  4PSY A;  4XEC X;  4KFJ A;  1JOM A;  1DR1 A;  3NTZ A;  3TQ9 A;  3SA2 A;  4PTJ A;  2BLC A;  4DPD A;  1DR7 A;  4XE6 X;  4H97 A;  3DFR A;  3IA4 A;  1HFP A;  1RG7 A;  3F0S X;  3M09 A;  4HOF A;  4EIL A;  1DR2 A;  1CD2 A;  1DYH A;  4EIG A;  4EIZ A;  4IXG X;  3EEM A;  4PST A;  1DR5 A;  2JYB A;  4OR7 A;  4CD2 A;  4RGC A;  1RH3 A;  4XT8 A;  4H98 A;  5CCC A;  1U72 A;  3NXR A;  1AI9 A;  4KYA A;  4M7U A;  5HQZ A;  3D80 A;  4QJC A;  1DLS A;  3NZ6 X;  3Q1H A;  1VJ3 A;  3SRW X;  1RF7 A;  1RX5 A;  4FGG A;  3F0V X;  4OSG A;  1KLK A;  1RX7 A;  1DIU A;  2XW7 A;  3EIG A;  4DDR A;  3OAF A;  2QK8 A;  1DRA A;  3QYL A;  2HM9 A;  1D1G A;  4G8Z X;  3K2H A;  4DPH A;  3SRU X;  2L28 A;  4PDJ A;  1SEJ A;  2W3A A;  1DG5 A;  1RX3 A;  3TQA A;  2FZH A;  5DFR A;  1DHJ A;  1DYR A;  4TU5 X;  2DHF A;  2G6V A;  5U27 A;  4X5F A;  4KJJ A;  1YHO A;  3F0B X;  4FHB A;  3FQZ A;  3E0B A;  3ZPC A;  5HSU A;  2C2S A;  2O7P A;  3TD8 A;  5HVE A;  4PTH A;  3JWM A;  4X5G A;  1DR6 A;  3FQV A;  4I13 A;  4KM0 A;  4QLE A;  2OBC A;  4X5I A;  4NX6 A;  3R33 A;  1U70 A;  4DFR A;  3SRR X;  3CLB A;  3QG2 A;  2D0K A;  3NZA X;  1OHK A;  5ECX A;  2ITH A;  3RG9 A;  1DG7 A;  1AOE A;  3SGY A;  1S3W A;  4HA9 A;  3EEL A;  3NXO A;  5CC9 A;  4H96 A;  2BL9 A;  3GYF A;  4ELG A;  3OCH A;  4QLF A;  3DL6 A;  3JW3 A;  3FQO A;  1RB3 A;  3INV A;  4XT4 A;  3IRO A;  4G3M A;  5HUI A;  3FL8 A;  3NZC X;  2HXV A;  3UM8 A;  4KY8 A;  3JSU A;  3KY8 A;  2W9S A;  4Q6A A;  3CSE A;  3QLS A;  3NZB X;  2FZJ A;  3NXX A;  4M6L A;  4QJZ D;  2H2Q A;  2CD2 A;  4ELE A;  2BLB A;  3LG4 A;  4H95 A;  5HVB A;  4P3Q A;  3SR5 X;  1CZ3 A;  5HI6 A;  3NRR A;  3K74 A;  5HSR A;  4KJK A;  1VDR A;  3NXV A;  4KL9 A;  1HFR A;  4LAH X; 
#chains in the Genus database with same CATH topology
 1RX8 A;  3GHW A;  4HOG A;  4M7V A;  5U26 A;  1DG8 A;  4ELH A;  4Q0E A;  4Q67 A;  1DR3 A;  2W9T A;  2W3M A;  2W3V A;  1RA9 A;  1J3I A;  3N0H A;  1OHJ A;  3DL5 A;  2KGK A;  3NZ9 X;  4XT6 A;  4M2X A;  3QGT A;  3IRM A;  3S3V A;  3SA1 A;  4KLX A;  3SQY X;  5EAJ A;  3K47 A;  4GH8 A;  1MVT A;  2HQP A;  3QLW A;  3FRA X;  3GI2 A;  3EX8 A;  3HJ3 A;  4KY4 A;  3CL9 A;  1DYJ A;  4QHV A;  1BZF A;  4ELB A;  3QLZ A;  1AO8 A;  1RX2 A;  1LY4 A;  3F8Y A;  4ELF A;  3FQF A;  3DGA A;  7DFR A;  1QZF A;  4KBN A;  4QI9 A;  3VCO A;  3F0X X;  1RA2 A;  4G95 A;  4M6K A;  8DFR A;  4X5J A;  3KJR A;  2OIP A;  4XT7 A;  2ANQ A;  3SRQ X;  4KEB A;  4P68 A;  5HF2 X;  2DRC A;  2GD9 A;  6DFR A;  1DLR A;  4IXF X;  3SH2 A;  1DF7 A;  4HA7 A;  3CD2 A;  1ZDR A;  2ANO A;  2W3W A;  2B3Z A;  3NXY A;  5DXV A;  3EEJ A;  3UM5 A;  4EJ1 A;  3F0Q X;  1RX4 A;  3FQ0 A;  3HBB A;  1RX1 A;  3FRF X;  1M78 A;  4LAG X;  4KNE A;  4KD7 A;  1PD9 A;  5E8Q A;  1RA8 A;  4P66 A;  1S3Y A;  3EEK A;  3IA5 A;  3L3R A;  1DDS A;  2BLA A;  2D5N A;  1JOL A;  4I1N A;  5HT5 A;  2ZZA A;  2W9G A;  3QLR A;  3DAT A;  1IA4 A;  3FL9 A;  4QLG A;  1IA3 A;  4XT5 A;  1LUD A;  4LAE X;  5FDA A;  3FY8 X;  1PDB A;  4FGH A;  5HPB A;  3JWF A;  3QLY A;  1RA3 A;  3JVX A;  3DRC A;  3DG8 A;  1PD8 A;  3QFX A;  1TDR A;  3TQB A;  3UM6 A;  1DRH A;  1RC4 A;  1BOZ A;  3I3R A;  3KJS A;  3FS6 A;  4XRB A;  1M79 A;  3S9U A;  5JA3 A;  4ECK A;  1HFQ A;  1KMV A;  4KAK A;  1DDR A;  4M6J A;  1DR4 A;  3I8A X;  4NX7 A;  1DRE A;  1DHF A;  3D84 X;  4LEK X;  4HOE A;  3DAU A;  5HQY A;  4IXE D;  1U71 A;  1DIS A;  4PSS A;  1JUV A;  3NZD A;  1DAJ A;  2FZI A;  1RE7 A;  3QYO A;  1MVS A;  1RB2 A;  3KFY A;  2W3B A;  3QLX A;  1DRF A;  3FYV X;  3K45 A;  3KGY A;  3RO9 A;  1RA1 A;  3QL3 A;  1DYI A;  1DHI A;  2LF1 A;  3FRD X;  1DRB A;  3QL0 A;  1RD7 A;  1LY3 A;  1IA1 A;  2AZN A;  4P3R A;  4KJL A;  3SRS X;  3FRE X;  3JTW A;  3NU0 A;  3FQC A;  4X5H A;  4KM2 A;  1RX6 A;  5JG0 X;  3F8Z A;  5ECC A;  2CIG A;  3TQ8 A;  1KMS A;  3GHV A;  5HF0 X;  3ROA A;  3ZPG A;  2W9H A;  4Q0D A;  1E26 A;  1RX9 A;  1S3V A;  2P4G A;  3FYW X;  5HT4 A;  2INQ A;  3FY9 X;  1J3K A;  3GHC A;  1M7A A;  3F0U X;  3JWK A;  3NXT A;  1IA2 A;  2C2T A;  3FRB X;  3S7A A;  1J3J A;  3F91 A;  3M08 A;  3JWC A;  3JW5 A;  1S3U A;  3IRN A;  4DP3 A;  3SAI A;  3IX9 A;  4PSY A;  4XEC X;  4KFJ A;  1JOM A;  1DR1 A;  3NTZ A;  3TQ9 A;  3SA2 A;  4PTJ A;  2BLC A;  4DPD A;  1DR7 A;  4XE6 X;  4H97 A;  3DFR A;  3IA4 A;  1HFP A;  1RG7 A;  3F0S X;  3M09 A;  4HOF A;  4EIL A;  1DR2 A;  1CD2 A;  1DYH A;  4EIG A;  4EIZ A;  4IXG X;  3EEM A;  4PST A;  1DR5 A;  2JYB A;  4OR7 A;  4CD2 A;  4RGC A;  1RH3 A;  4XT8 A;  4H98 A;  5CCC A;  1U72 A;  3NXR A;  1AI9 A;  4KYA A;  4M7U A;  5HQZ A;  3D80 A;  4QJC A;  1DLS A;  3NZ6 X;  3Q1H A;  1VJ3 A;  3SRW X;  1RF7 A;  1RX5 A;  4FGG A;  3F0V X;  4OSG A;  1KLK A;  1RX7 A;  1DIU A;  2XW7 A;  3EIG A;  4DDR A;  3OAF A;  2QK8 A;  1DRA A;  3QYL A;  2HM9 A;  1D1G A;  4G8Z X;  3K2H A;  4DPH A;  3SRU X;  2L28 A;  4PDJ A;  1SEJ A;  2W3A A;  1DG5 A;  1RX3 A;  3TQA A;  2FZH A;  5DFR A;  1DHJ A;  1DYR A;  4TU5 X;  2DHF A;  2G6V A;  5U27 A;  4X5F A;  4KJJ A;  1YHO A;  3F0B X;  4FHB A;  3FQZ A;  3E0B A;  3ZPC A;  5HSU A;  2C2S A;  2O7P A;  3TD8 A;  5HVE A;  4PTH A;  3JWM A;  4X5G A;  1DR6 A;  3FQV A;  4I13 A;  4KM0 A;  4QLE A;  2OBC A;  4X5I A;  4NX6 A;  3R33 A;  1U70 A;  4DFR A;  3SRR X;  3CLB A;  3QG2 A;  2D0K A;  3NZA X;  1OHK A;  5ECX A;  2ITH A;  3RG9 A;  1DG7 A;  1AOE A;  3SGY A;  1S3W A;  4HA9 A;  3EEL A;  3NXO A;  5CC9 A;  4H96 A;  2BL9 A;  3GYF A;  4ELG A;  3OCH A;  4QLF A;  3DL6 A;  3JW3 A;  3FQO A;  1RB3 A;  3INV A;  4XT4 A;  3IRO A;  4G3M A;  5HUI A;  3FL8 A;  3NZC X;  2HXV A;  3UM8 A;  4KY8 A;  3JSU A;  3KY8 A;  2W9S A;  4Q6A A;  3CSE A;  3QLS A;  3NZB X;  2FZJ A;  3NXX A;  4M6L A;  4QJZ D;  2H2Q A;  2CD2 A;  4ELE A;  2BLB A;  3LG4 A;  4H95 A;  5HVB A;  4P3Q A;  3SR5 X;  1CZ3 A;  5HI6 A;  3NRR A;  3K74 A;  5HSR A;  4KJK A;  1VDR A;  3NXV A;  4KL9 A;  1HFR A;  4LAH X; 
#chains in the Genus database with same CATH homology
 1RX8 A;  3GHW A;  4HOG A;  4M7V A;  5U26 A;  1DG8 A;  4ELH A;  4Q0E A;  4Q67 A;  1DR3 A;  2W9T A;  2W3M A;  2W3V A;  1RA9 A;  1J3I A;  3N0H A;  1OHJ A;  3DL5 A;  2KGK A;  3NZ9 X;  4XT6 A;  4M2X A;  3QGT A;  3IRM A;  3S3V A;  3SA1 A;  4KLX A;  3SQY X;  5EAJ A;  3K47 A;  4GH8 A;  1MVT A;  2HQP A;  3QLW A;  3FRA X;  3GI2 A;  3EX8 A;  3HJ3 A;  4KY4 A;  3CL9 A;  1DYJ A;  4QHV A;  1BZF A;  4ELB A;  3QLZ A;  1AO8 A;  1RX2 A;  1LY4 A;  3F8Y A;  4ELF A;  3FQF A;  3DGA A;  7DFR A;  1QZF A;  4KBN A;  4QI9 A;  3VCO A;  3F0X X;  1RA2 A;  4G95 A;  4M6K A;  8DFR A;  4X5J A;  3KJR A;  2OIP A;  4XT7 A;  2ANQ A;  3SRQ X;  4KEB A;  4P68 A;  5HF2 X;  2DRC A;  2GD9 A;  6DFR A;  1DLR A;  4IXF X;  3SH2 A;  1DF7 A;  4HA7 A;  3CD2 A;  1ZDR A;  2ANO A;  2W3W A;  2B3Z A;  3NXY A;  5DXV A;  3EEJ A;  3UM5 A;  4EJ1 A;  3F0Q X;  1RX4 A;  3FQ0 A;  3HBB A;  1RX1 A;  3FRF X;  1M78 A;  4LAG X;  4KNE A;  4KD7 A;  1PD9 A;  5E8Q A;  1RA8 A;  4P66 A;  1S3Y A;  3EEK A;  3IA5 A;  3L3R A;  1DDS A;  2BLA A;  2D5N A;  1JOL A;  4I1N A;  5HT5 A;  2ZZA A;  2W9G A;  3QLR A;  3DAT A;  1IA4 A;  3FL9 A;  4QLG A;  1IA3 A;  4XT5 A;  1LUD A;  4LAE X;  5FDA A;  3FY8 X;  1PDB A;  4FGH A;  5HPB A;  3JWF A;  3QLY A;  1RA3 A;  3JVX A;  3DRC A;  3DG8 A;  1PD8 A;  3QFX A;  1TDR A;  3TQB A;  3UM6 A;  1DRH A;  1RC4 A;  1BOZ A;  3I3R A;  3KJS A;  3FS6 A;  4XRB A;  1M79 A;  3S9U A;  5JA3 A;  4ECK A;  1HFQ A;  1KMV A;  4KAK A;  1DDR A;  4M6J A;  1DR4 A;  3I8A X;  4NX7 A;  1DRE A;  1DHF A;  3D84 X;  4LEK X;  4HOE A;  3DAU A;  5HQY A;  4IXE D;  1U71 A;  1DIS A;  4PSS A;  1JUV A;  3NZD A;  1DAJ A;  2FZI A;  1RE7 A;  3QYO A;  1MVS A;  1RB2 A;  3KFY A;  2W3B A;  3QLX A;  1DRF A;  3FYV X;  3K45 A;  3KGY A;  3RO9 A;  1RA1 A;  3QL3 A;  1DYI A;  1DHI A;  2LF1 A;  3FRD X;  1DRB A;  3QL0 A;  1RD7 A;  1LY3 A;  1IA1 A;  2AZN A;  4P3R A;  4KJL A;  3SRS X;  3FRE X;  3JTW A;  3NU0 A;  3FQC A;  4X5H A;  4KM2 A;  1RX6 A;  5JG0 X;  3F8Z A;  5ECC A;  2CIG A;  3TQ8 A;  1KMS A;  3GHV A;  5HF0 X;  3ROA A;  3ZPG A;  2W9H A;  4Q0D A;  1E26 A;  1RX9 A;  1S3V A;  2P4G A;  3FYW X;  5HT4 A;  2INQ A;  3FY9 X;  1J3K A;  3GHC A;  1M7A A;  3F0U X;  3JWK A;  3NXT A;  1IA2 A;  2C2T A;  3FRB X;  3S7A A;  1J3J A;  3F91 A;  3M08 A;  3JWC A;  3JW5 A;  1S3U A;  3IRN A;  4DP3 A;  3SAI A;  3IX9 A;  4PSY A;  4XEC X;  4KFJ A;  1JOM A;  1DR1 A;  3NTZ A;  3TQ9 A;  3SA2 A;  4PTJ A;  2BLC A;  4DPD A;  1DR7 A;  4XE6 X;  4H97 A;  3DFR A;  3IA4 A;  1HFP A;  1RG7 A;  3F0S X;  3M09 A;  4HOF A;  4EIL A;  1DR2 A;  1CD2 A;  1DYH A;  4EIG A;  4EIZ A;  4IXG X;  3EEM A;  4PST A;  1DR5 A;  2JYB A;  4OR7 A;  4CD2 A;  4RGC A;  1RH3 A;  4XT8 A;  4H98 A;  5CCC A;  1U72 A;  3NXR A;  1AI9 A;  4KYA A;  4M7U A;  5HQZ A;  3D80 A;  4QJC A;  1DLS A;  3NZ6 X;  3Q1H A;  1VJ3 A;  3SRW X;  1RF7 A;  1RX5 A;  4FGG A;  3F0V X;  4OSG A;  1KLK A;  1RX7 A;  1DIU A;  2XW7 A;  3EIG A;  4DDR A;  3OAF A;  2QK8 A;  1DRA A;  3QYL A;  2HM9 A;  1D1G A;  4G8Z X;  3K2H A;  4DPH A;  3SRU X;  2L28 A;  4PDJ A;  1SEJ A;  2W3A A;  1DG5 A;  1RX3 A;  3TQA A;  2FZH A;  5DFR A;  1DHJ A;  1DYR A;  4TU5 X;  2DHF A;  2G6V A;  5U27 A;  4X5F A;  4KJJ A;  1YHO A;  3F0B X;  4FHB A;  3FQZ A;  3E0B A;  3ZPC A;  5HSU A;  2C2S A;  2O7P A;  3TD8 A;  5HVE A;  4PTH A;  3JWM A;  4X5G A;  1DR6 A;  3FQV A;  4I13 A;  4KM0 A;  4QLE A;  2OBC A;  4X5I A;  4NX6 A;  3R33 A;  1U70 A;  4DFR A;  3SRR X;  3CLB A;  3QG2 A;  2D0K A;  3NZA X;  1OHK A;  5ECX A;  2ITH A;  3RG9 A;  1DG7 A;  1AOE A;  3SGY A;  1S3W A;  4HA9 A;  3EEL A;  3NXO A;  5CC9 A;  4H96 A;  2BL9 A;  3GYF A;  4ELG A;  3OCH A;  4QLF A;  3DL6 A;  3JW3 A;  3FQO A;  1RB3 A;  3INV A;  4XT4 A;  3IRO A;  4G3M A;  5HUI A;  3FL8 A;  3NZC X;  2HXV A;  3UM8 A;  4KY8 A;  3JSU A;  3KY8 A;  2W9S A;  4Q6A A;  3CSE A;  3QLS A;  3NZB X;  2FZJ A;  3NXX A;  4M6L A;  4QJZ D;  2H2Q A;  2CD2 A;  4ELE A;  2BLB A;  3LG4 A;  4H95 A;  5HVB A;  4P3Q A;  3SR5 X;  1CZ3 A;  5HI6 A;  3NRR A;  3K74 A;  5HSR A;  4KJK A;  1VDR A;  3NXV A;  4KL9 A;  1HFR A;  4LAH X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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