1GD5A

Solution structure of the px domain from human p47phox nadph oxidase
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
130
structure length
130
Chain Sequence
GSMGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMSLPTKISRCPHLLDFFKVRPDDLKLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the PX domain, a target of the SH3 domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords NEUTROPHIL CYTOSOL FACTOR 1
total genus 29
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2000-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 1gd5A00
1OCSA 1GD5A 1H6HA 2CZOA 2RAJA 2WWEA 2REDA 2L73A 4PQPA 4ON3A 3HPBA 1OCUA 2I4KA 1KQ6A 3HPCX 4AZ9A 3FOGA 2DYBA 4OXWA 2RAIA 4HASA 4IKBA 2ETTA 3DYTA 3P0CA 2V6VA 3LUIA 4IKDA 2IWLX 2YPSA 4BGJA 4PZGA 4P2IA 1XTNA 2AR5A 4P2JA 4IKBB 2V14A 2CSKA 4PQOA 1KMDA 1XTEA 2RAKA 2REAA 4AKVA 3IQ2A 1O7KA
chains in the Genus database with same CATH superfamily
1OCSA 1GD5A 1H6HA 2CZOA 2RAJA 2WWEA 2REDA 2L73A 4PQPA 4ON3A 3HPBA 1OCUA 2I4KA 1KQ6A 3HPCX 4AZ9A 3FOGA 2DYBA 4OXWA 2RAIA 4HASA 4IKBA 2ETTA 3DYTA 3P0CA 2V6VA 3LUIA 4IKDA 2IWLX 2YPSA 4BGJA 4PZGA 4P2IA 1XTNA 2AR5A 4P2JA 4IKBB 2V14A 2CSKA 4PQOA 1KMDA 1XTEA 2RAKA 2REAA 4AKVA 3IQ2A 1O7KA
chains in the Genus database with same CATH topology
1OCSA 1GD5A 1H6HA 2CZOA 2RAJA 2WWEA 2REDA 2L73A 4PQPA 4ON3A 3HPBA 1OCUA 2I4KA 1KQ6A 3HPCX 4AZ9A 3FOGA 2DYBA 4OXWA 2RAIA 4HASA 4IKBA 2ETTA 3DYTA 3P0CA 2V6VA 3LUIA 4IKDA 2IWLX 2YPSA 4BGJA 4PZGA 4P2IA 1XTNA 2AR5A 4P2JA 4IKBB 2V14A 2CSKA 4PQOA 1KMDA 1XTEA 2RAKA 2REAA 4AKVA 3IQ2A 1O7KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OCS A;  1GD5 A;  1H6H A;  2CZO A;  2RAJ A;  2WWE A;  2RED A;  2L73 A;  4PQP A;  4ON3 A;  3HPB A;  1OCU A;  2I4K A;  1KQ6 A;  3HPC X;  4AZ9 A;  3FOG A;  2DYB A;  4OXW A;  2RAI A;  4HAS A;  4IKB A;  2ETT A;  3DYT A;  3P0C A;  2V6V A;  3LUI A;  4IKD A;  2IWL X;  2YPS A;  4BGJ A;  4PZG A;  4P2I A;  1XTN A;  2AR5 A;  4P2J A;  4IKB B;  2V14 A;  2CSK A;  4PQO A;  1KMD A;  1XTE A;  2RAK A;  2REA A;  4AKV A;  3IQ2 A;  1O7K A; 
#chains in the Genus database with same CATH topology
 1OCS A;  1GD5 A;  1H6H A;  2CZO A;  2RAJ A;  2WWE A;  2RED A;  2L73 A;  4PQP A;  4ON3 A;  3HPB A;  1OCU A;  2I4K A;  1KQ6 A;  3HPC X;  4AZ9 A;  3FOG A;  2DYB A;  4OXW A;  2RAI A;  4HAS A;  4IKB A;  2ETT A;  3DYT A;  3P0C A;  2V6V A;  3LUI A;  4IKD A;  2IWL X;  2YPS A;  4BGJ A;  4PZG A;  4P2I A;  1XTN A;  2AR5 A;  4P2J A;  4IKB B;  2V14 A;  2CSK A;  4PQO A;  1KMD A;  1XTE A;  2RAK A;  2REA A;  4AKV A;  3IQ2 A;  1O7K A; 
#chains in the Genus database with same CATH homology
 1OCS A;  1GD5 A;  1H6H A;  2CZO A;  2RAJ A;  2WWE A;  2RED A;  2L73 A;  4PQP A;  4ON3 A;  3HPB A;  1OCU A;  2I4K A;  1KQ6 A;  3HPC X;  4AZ9 A;  3FOG A;  2DYB A;  4OXW A;  2RAI A;  4HAS A;  4IKB A;  2ETT A;  3DYT A;  3P0C A;  2V6V A;  3LUI A;  4IKD A;  2IWL X;  2YPS A;  4BGJ A;  4PZG A;  4P2I A;  1XTN A;  2AR5 A;  4P2J A;  4IKB B;  2V14 A;  2CSK A;  4PQO A;  1KMD A;  1XTE A;  2RAK A;  2REA A;  4AKV A;  3IQ2 A;  1O7K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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