1IA1A

Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 5-(phenylsulfanyl)-2,4-quinazolinediamine (gw997)
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
192
structure length
192
Chain Sequence
MLKPNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase: High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH is Displaced by an inhibitor
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Candida albicans
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 57
structure length 192
sequence length 192
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2001-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1ia1A00
4KJJA 5DXVA 3RG9A 3D84X 3M08A 3SRQX 3IRNA 3ZPGA 1RC4A 4OR7A 4EIGA 3EEMA 4XT6A 2W3VA 3SGYA 6DFRA 4X5JA 2W3WA 1DDSA 2DRCA 3FQOA 3JTWA 4QLEA 3K47A 1S3YA 3QYLA 1HFQA 4ELGA 4LAEX 4Q6AA 1DIUA 1RF7A 4QJCA 3FQ0A 3JWFA 1IA2A 3QGTA 3S7AA 3SRSX 4KAKA 3CL9A 3JW3A 3QL3A 3NRRA 3DG8A 1RA1A 2L28A 3JWMA 4LAHX 5HI6A 4QI9A 3FQCA 4M6LA 4X5HA 3JSUA 2DHFA 4HA7A 1RB3A 4KFJA 1DG7A 1RX9A 4QJZD 3SA2A 2W9GA 4IXGX 1KMVA 3NZDA 4HA9A 3TD8A 3FY8X 1RX5A 4KL9A 4FHBA 3QLRA 3L3RA 1DHIA 3Q1HA 4LEKX 3SR5X 1PDBA 2D5NA 5HT4A 2HXVA 1DR2A 2O7PA 4Q0DA 1OHKA 4QHVA 4KLXA 4EJ1A 4KM0A 4ELHA 2G6VA 3NU0A 3IA5A 4DPDA 1M78A 1U70A 1DG5A 1SEJA 2CD2A 2ANQA 3JWCA 4KYAA 5CC9A 3FQZA 1AO8A 2D0KA 4IXED 3M09A 3CSEA 1KMSA 1RA9A 3F8ZA 3DGAA 4KJLA 1DF7A 4XRBA 5JA3A 3DRCA 3KJSA 2AZNA 3QFXA 4PSTA 4I13A 3HJ3A 3QG2A 1U72A 1DG8A 4XT4A 3SRUX 5JG0X 2BLCA 1IA4A 2C2TA 3NXRA 4QLFA 5FDAA 3KY8A 1LY4A 2W3MA 3DFRA 3HBBA 3SRRX 1PD9A 1DREA 1IA1A 5HQYA 2BLAA 4G95A 3GI2A 4KJKA 1JUVA 3SQYX 4ELBA 3E0BA 3I3RA 1CD2A 4HOEA 1HFPA 4P66A 2LF1A 4RGCA 3ZPCA 3NZ6X 3JWKA 3FRDX 3F0XX 4ELEA 5HSRA 3GHVA 1DLSA 3TQAA 4P3QA 1HFRA 4CD2A 1RX3A 5EAJA 4OSGA 1AI9A 4X5IA 4ELFA 3F8YA 3CD2A 1RB2A 4LAGX 1S3WA 1DDRA 3SRWX 1RX1A 4XT5A 2BLBA 3EELA 1RA8A 4M6JA 1RD7A 3KFYA 4H97A 1TDRA 2ITHA 7DFRA 3JVXA 5HSUA 1PD8A 2CIGA 2GD9A 4DFRA 4X5GA 3SA1A 3INVA 3GYFA 4PTHA 3FQFA 2ZZAA 1AOEA 3UM5A 3QLXA 3NTZA 3VCOA 3CLBA 3R33A 1DHFA 3IRMA 3FRBX 4M7VA 3SAIA 3K74A 3S3VA 3EEKA 5U27A 3SH2A 5ECCA 5DFRA 3NXOA 3DATA 1LY3A 4EILA 1LUDA 3DL5A 4XT7A 1RX7A 4PSYA 1DR3A 4KEBA 1BZFA 4Q67A 1CZ3A 1DR4A 1J3IA 1KLKA 1QZFA 1S3UA 3F0SX 3NZBX 2FZHA 4Q0EA 1J3JA 1DR1A 2P4GA 4M6KA 4KY4A 4XE6X 1M79A 3QL0A 3LG4A 3EX8A 4HOGA 1E26A 4M2XA 1MVTA 1RX8A 1DR7A 1BOZA 1D1GA 3K2HA 2JYBA 1DAJA 3OCHA 2INQA 2HM9A 4HOFA 4M7UA 4FGGA 3FL9A 1M7AA 3UM8A 3UM6A 3F0UX 4P3RA 1RX6A 3F0BX 3QYOA 4G8ZX 1DYRA 1RA2A 4X5FA 1S3VA 5HT5A 3RO9A 3FL8A 1DYIA 1IA3A 2W9SA 1DYHA 3IX9A 4H98A 4PDJA 1DR6A 3K45A 3QLSA 5HF0X 1DRAA 1RE7A 4H96A 3GHWA 4DP3A 3NZAX 2HQPA 4G3MA 5HQZA 1RH3A 5HVBA 1DR5A 4PTJA 1DRFA 4KY8A 4DPHA 1VJ3A 4KBNA 2BL9A 3FS6A 2B3ZA 3TQ8A 4XECX 3D80A 3FYVX 4XT8A 4H95A 4NX7A 4EIZA 8DFRA 2KGKA 2XW7A 4TU5X 2W9HA 4KM2A 3EEJA 3DAUA 4ECKA 3OAFA 4P68A 5ECXA 3TQBA 2C2SA 1OHJA 3FY9X 1JOLA 3NXYA 4PSSA 3QLZA 3NZCX 1YHOA 3I8AX 2OIPA 3DL6A 3FRAX 5HPBA 3NXVA 1RX4A 3JW5A 3F0VX 1ZDRA 4FGHA 4IXFX 1U71A 3TQ9A 1J3KA 3NZ9X 3GHCA 5HUIA 1RA3A 5E8QA 1DISA 2W3BA 1DRHA 1VDRA 2OBCA 3EIGA 3IROA 1DYJA 1RX2A 3FRFX 3QLYA 3F0QX 1DLRA 3S9UA 2FZIA 4DDRA 3NXXA 1RG7A 3QLWA 1MVSA 3NXTA 1JOMA 3FYWX 1DRBA 5U26A 2W3AA 3ROAA 3F91A 4NX6A 2FZJA 3IA4A 2H2QA 4I1NA 3FQVA 3KJRA 3N0HA 5HF2X 3KGYA 4GH8A 1DHJA 2ANOA 2W9TA 4KNEA 5HVEA 5CCCA 4KD7A 4QLGA 3FREX 2QK8A
chains in the Genus database with same CATH superfamily
4KJJA 5DXVA 3RG9A 3D84X 3M08A 3SRQX 3IRNA 3ZPGA 1RC4A 4OR7A 4EIGA 3EEMA 4XT6A 2W3VA 3SGYA 6DFRA 4X5JA 2W3WA 1DDSA 2DRCA 3FQOA 3JTWA 4QLEA 3K47A 1S3YA 3QYLA 1HFQA 4ELGA 4LAEX 4Q6AA 1DIUA 1RF7A 4QJCA 3FQ0A 3JWFA 1IA2A 3QGTA 3S7AA 3SRSX 4KAKA 3CL9A 3JW3A 3QL3A 3NRRA 3DG8A 1RA1A 2L28A 3JWMA 4LAHX 5HI6A 4QI9A 3FQCA 4M6LA 4X5HA 3JSUA 2DHFA 4HA7A 1RB3A 4KFJA 1DG7A 1RX9A 4QJZD 3SA2A 2W9GA 4IXGX 1KMVA 3NZDA 4HA9A 3TD8A 3FY8X 1RX5A 4KL9A 4FHBA 3QLRA 3L3RA 1DHIA 3Q1HA 4LEKX 3SR5X 1PDBA 2D5NA 5HT4A 2HXVA 1DR2A 2O7PA 4Q0DA 1OHKA 4QHVA 4KLXA 4EJ1A 4KM0A 4ELHA 2G6VA 3NU0A 3IA5A 4DPDA 1M78A 1U70A 1DG5A 1SEJA 2CD2A 2ANQA 3JWCA 4KYAA 5CC9A 3FQZA 1AO8A 2D0KA 4IXED 3M09A 3CSEA 1KMSA 1RA9A 3F8ZA 3DGAA 4KJLA 1DF7A 4XRBA 5JA3A 3DRCA 3KJSA 2AZNA 3QFXA 4PSTA 4I13A 3HJ3A 3QG2A 1U72A 1DG8A 4XT4A 3SRUX 5JG0X 2BLCA 1IA4A 2C2TA 3NXRA 4QLFA 5FDAA 3KY8A 1LY4A 2W3MA 3DFRA 3HBBA 3SRRX 1PD9A 1DREA 1IA1A 5HQYA 2BLAA 4G95A 3GI2A 4KJKA 1JUVA 3SQYX 4ELBA 3E0BA 3I3RA 1CD2A 4HOEA 1HFPA 4P66A 2LF1A 4RGCA 3ZPCA 3NZ6X 3JWKA 3FRDX 3F0XX 4ELEA 5HSRA 3GHVA 1DLSA 3TQAA 4P3QA 1HFRA 4CD2A 1RX3A 5EAJA 4OSGA 1AI9A 4X5IA 4ELFA 3F8YA 3CD2A 1RB2A 4LAGX 1S3WA 1DDRA 3SRWX 1RX1A 4XT5A 2BLBA 3EELA 1RA8A 4M6JA 1RD7A 3KFYA 4H97A 1TDRA 2ITHA 7DFRA 3JVXA 5HSUA 1PD8A 2CIGA 2GD9A 4DFRA 4X5GA 3SA1A 3INVA 3GYFA 4PTHA 3FQFA 2ZZAA 1AOEA 3UM5A 3QLXA 3NTZA 3VCOA 3CLBA 3R33A 1DHFA 3IRMA 3FRBX 4M7VA 3SAIA 3K74A 3S3VA 3EEKA 5U27A 3SH2A 5ECCA 5DFRA 3NXOA 3DATA 1LY3A 4EILA 1LUDA 3DL5A 4XT7A 1RX7A 4PSYA 1DR3A 4KEBA 1BZFA 4Q67A 1CZ3A 1DR4A 1J3IA 1KLKA 1QZFA 1S3UA 3F0SX 3NZBX 2FZHA 4Q0EA 1J3JA 1DR1A 2P4GA 4M6KA 4KY4A 4XE6X 1M79A 3QL0A 3LG4A 3EX8A 4HOGA 1E26A 4M2XA 1MVTA 1RX8A 1DR7A 1BOZA 1D1GA 3K2HA 2JYBA 1DAJA 3OCHA 2INQA 2HM9A 4HOFA 4M7UA 4FGGA 3FL9A 1M7AA 3UM8A 3UM6A 3F0UX 4P3RA 1RX6A 3F0BX 3QYOA 4G8ZX 1DYRA 1RA2A 4X5FA 1S3VA 5HT5A 3RO9A 3FL8A 1DYIA 1IA3A 2W9SA 1DYHA 3IX9A 4H98A 4PDJA 1DR6A 3K45A 3QLSA 5HF0X 1DRAA 1RE7A 4H96A 3GHWA 4DP3A 3NZAX 2HQPA 4G3MA 5HQZA 1RH3A 5HVBA 1DR5A 4PTJA 1DRFA 4KY8A 4DPHA 1VJ3A 4KBNA 2BL9A 3FS6A 2B3ZA 3TQ8A 4XECX 3D80A 3FYVX 4XT8A 4H95A 4NX7A 4EIZA 8DFRA 2KGKA 2XW7A 4TU5X 2W9HA 4KM2A 3EEJA 3DAUA 4ECKA 3OAFA 4P68A 5ECXA 3TQBA 2C2SA 1OHJA 3FY9X 1JOLA 3NXYA 4PSSA 3QLZA 3NZCX 1YHOA 3I8AX 2OIPA 3DL6A 3FRAX 5HPBA 3NXVA 1RX4A 3JW5A 3F0VX 1ZDRA 4FGHA 4IXFX 1U71A 3TQ9A 1J3KA 3NZ9X 3GHCA 5HUIA 1RA3A 5E8QA 1DISA 2W3BA 1DRHA 1VDRA 2OBCA 3EIGA 3IROA 1DYJA 1RX2A 3FRFX 3QLYA 3F0QX 1DLRA 3S9UA 2FZIA 4DDRA 3NXXA 1RG7A 3QLWA 1MVSA 3NXTA 1JOMA 3FYWX 1DRBA 5U26A 2W3AA 3ROAA 3F91A 4NX6A 2FZJA 3IA4A 2H2QA 4I1NA 3FQVA 3KJRA 3N0HA 5HF2X 3KGYA 4GH8A 1DHJA 2ANOA 2W9TA 4KNEA 5HVEA 5CCCA 4KD7A 4QLGA 3FREX 2QK8A
chains in the Genus database with same CATH topology
4KJJA 5DXVA 3RG9A 3D84X 3M08A 3SRQX 3IRNA 3ZPGA 1RC4A 4OR7A 4EIGA 3EEMA 4XT6A 2W3VA 3SGYA 6DFRA 4X5JA 2W3WA 1DDSA 2DRCA 3FQOA 3JTWA 4QLEA 3K47A 1S3YA 3QYLA 1HFQA 4ELGA 4LAEX 4Q6AA 1DIUA 1RF7A 4QJCA 3FQ0A 3JWFA 1IA2A 3QGTA 3S7AA 3SRSX 4KAKA 3CL9A 3JW3A 3QL3A 3NRRA 3DG8A 1RA1A 2L28A 3JWMA 4LAHX 5HI6A 4QI9A 3FQCA 4M6LA 4X5HA 3JSUA 2DHFA 4HA7A 1RB3A 4KFJA 1DG7A 1RX9A 4QJZD 3SA2A 2W9GA 4IXGX 1KMVA 3NZDA 4HA9A 3TD8A 3FY8X 1RX5A 4KL9A 4FHBA 3QLRA 3L3RA 1DHIA 3Q1HA 4LEKX 3SR5X 1PDBA 2D5NA 5HT4A 2HXVA 1DR2A 2O7PA 4Q0DA 1OHKA 4QHVA 4KLXA 4EJ1A 4KM0A 4ELHA 2G6VA 3NU0A 3IA5A 4DPDA 1M78A 1U70A 1DG5A 1SEJA 2CD2A 2ANQA 3JWCA 4KYAA 5CC9A 3FQZA 1AO8A 2D0KA 4IXED 3M09A 3CSEA 1KMSA 1RA9A 3F8ZA 3DGAA 4KJLA 1DF7A 4XRBA 5JA3A 3DRCA 3KJSA 2AZNA 3QFXA 4PSTA 4I13A 3HJ3A 3QG2A 1U72A 1DG8A 4XT4A 3SRUX 5JG0X 2BLCA 1IA4A 2C2TA 3NXRA 4QLFA 5FDAA 3KY8A 1LY4A 2W3MA 3DFRA 3HBBA 3SRRX 1PD9A 1DREA 1IA1A 5HQYA 2BLAA 4G95A 3GI2A 4KJKA 1JUVA 3SQYX 4ELBA 3E0BA 3I3RA 1CD2A 4HOEA 1HFPA 4P66A 2LF1A 4RGCA 3ZPCA 3NZ6X 3JWKA 3FRDX 3F0XX 4ELEA 5HSRA 3GHVA 1DLSA 3TQAA 4P3QA 1HFRA 4CD2A 1RX3A 5EAJA 4OSGA 1AI9A 4X5IA 4ELFA 3F8YA 3CD2A 1RB2A 4LAGX 1S3WA 1DDRA 3SRWX 1RX1A 4XT5A 2BLBA 3EELA 1RA8A 4M6JA 1RD7A 3KFYA 4H97A 1TDRA 2ITHA 7DFRA 3JVXA 5HSUA 1PD8A 2CIGA 2GD9A 4DFRA 4X5GA 3SA1A 3INVA 3GYFA 4PTHA 3FQFA 2ZZAA 1AOEA 3UM5A 3QLXA 3NTZA 3VCOA 3CLBA 3R33A 1DHFA 3IRMA 3FRBX 4M7VA 3SAIA 3K74A 3S3VA 3EEKA 5U27A 3SH2A 5ECCA 5DFRA 3NXOA 3DATA 1LY3A 4EILA 1LUDA 3DL5A 4XT7A 1RX7A 4PSYA 1DR3A 4KEBA 1BZFA 4Q67A 1CZ3A 1DR4A 1J3IA 1KLKA 1QZFA 1S3UA 3F0SX 3NZBX 2FZHA 4Q0EA 1J3JA 1DR1A 2P4GA 4M6KA 4KY4A 4XE6X 1M79A 3QL0A 3LG4A 3EX8A 4HOGA 1E26A 4M2XA 1MVTA 1RX8A 1DR7A 1BOZA 1D1GA 3K2HA 2JYBA 1DAJA 3OCHA 2INQA 2HM9A 4HOFA 4M7UA 4FGGA 3FL9A 1M7AA 3UM8A 3UM6A 3F0UX 4P3RA 1RX6A 3F0BX 3QYOA 4G8ZX 1DYRA 1RA2A 4X5FA 1S3VA 5HT5A 3RO9A 3FL8A 1DYIA 1IA3A 2W9SA 1DYHA 3IX9A 4H98A 4PDJA 1DR6A 3K45A 3QLSA 5HF0X 1DRAA 1RE7A 4H96A 3GHWA 4DP3A 3NZAX 2HQPA 4G3MA 5HQZA 1RH3A 5HVBA 1DR5A 4PTJA 1DRFA 4KY8A 4DPHA 1VJ3A 4KBNA 2BL9A 3FS6A 2B3ZA 3TQ8A 4XECX 3D80A 3FYVX 4XT8A 4H95A 4NX7A 4EIZA 8DFRA 2KGKA 2XW7A 4TU5X 2W9HA 4KM2A 3EEJA 3DAUA 4ECKA 3OAFA 4P68A 5ECXA 3TQBA 2C2SA 1OHJA 3FY9X 1JOLA 3NXYA 4PSSA 3QLZA 3NZCX 1YHOA 3I8AX 2OIPA 3DL6A 3FRAX 5HPBA 3NXVA 1RX4A 3JW5A 3F0VX 1ZDRA 4FGHA 4IXFX 1U71A 3TQ9A 1J3KA 3NZ9X 3GHCA 5HUIA 1RA3A 5E8QA 1DISA 2W3BA 1DRHA 1VDRA 2OBCA 3EIGA 3IROA 1DYJA 1RX2A 3FRFX 3QLYA 3F0QX 1DLRA 3S9UA 2FZIA 4DDRA 3NXXA 1RG7A 3QLWA 1MVSA 3NXTA 1JOMA 3FYWX 1DRBA 5U26A 2W3AA 3ROAA 3F91A 4NX6A 2FZJA 3IA4A 2H2QA 4I1NA 3FQVA 3KJRA 3N0HA 5HF2X 3KGYA 4GH8A 1DHJA 2ANOA 2W9TA 4KNEA 5HVEA 5CCCA 4KD7A 4QLGA 3FREX 2QK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KJJ A;  5DXV A;  3RG9 A;  3D84 X;  3M08 A;  3SRQ X;  3IRN A;  3ZPG A;  1RC4 A;  4OR7 A;  4EIG A;  3EEM A;  4XT6 A;  2W3V A;  3SGY A;  6DFR A;  4X5J A;  2W3W A;  1DDS A;  2DRC A;  3FQO A;  3JTW A;  4QLE A;  3K47 A;  1S3Y A;  3QYL A;  1HFQ A;  4ELG A;  4LAE X;  4Q6A A;  1DIU A;  1RF7 A;  4QJC A;  3FQ0 A;  3JWF A;  1IA2 A;  3QGT A;  3S7A A;  3SRS X;  4KAK A;  3CL9 A;  3JW3 A;  3QL3 A;  3NRR A;  3DG8 A;  1RA1 A;  2L28 A;  3JWM A;  4LAH X;  5HI6 A;  4QI9 A;  3FQC A;  4M6L A;  4X5H A;  3JSU A;  2DHF A;  4HA7 A;  1RB3 A;  4KFJ A;  1DG7 A;  1RX9 A;  4QJZ D;  3SA2 A;  2W9G A;  4IXG X;  1KMV A;  3NZD A;  4HA9 A;  3TD8 A;  3FY8 X;  1RX5 A;  4KL9 A;  4FHB A;  3QLR A;  3L3R A;  1DHI A;  3Q1H A;  4LEK X;  3SR5 X;  1PDB A;  2D5N A;  5HT4 A;  2HXV A;  1DR2 A;  2O7P A;  4Q0D A;  1OHK A;  4QHV A;  4KLX A;  4EJ1 A;  4KM0 A;  4ELH A;  2G6V A;  3NU0 A;  3IA5 A;  4DPD A;  1M78 A;  1U70 A;  1DG5 A;  1SEJ A;  2CD2 A;  2ANQ A;  3JWC A;  4KYA A;  5CC9 A;  3FQZ A;  1AO8 A;  2D0K A;  4IXE D;  3M09 A;  3CSE A;  1KMS A;  1RA9 A;  3F8Z A;  3DGA A;  4KJL A;  1DF7 A;  4XRB A;  5JA3 A;  3DRC A;  3KJS A;  2AZN A;  3QFX A;  4PST A;  4I13 A;  3HJ3 A;  3QG2 A;  1U72 A;  1DG8 A;  4XT4 A;  3SRU X;  5JG0 X;  2BLC A;  1IA4 A;  2C2T A;  3NXR A;  4QLF A;  5FDA A;  3KY8 A;  1LY4 A;  2W3M A;  3DFR A;  3HBB A;  3SRR X;  1PD9 A;  1DRE A;  1IA1 A;  5HQY A;  2BLA A;  4G95 A;  3GI2 A;  4KJK A;  1JUV A;  3SQY X;  4ELB A;  3E0B A;  3I3R A;  1CD2 A;  4HOE A;  1HFP A;  4P66 A;  2LF1 A;  4RGC A;  3ZPC A;  3NZ6 X;  3JWK A;  3FRD X;  3F0X X;  4ELE A;  5HSR A;  3GHV A;  1DLS A;  3TQA A;  4P3Q A;  1HFR A;  4CD2 A;  1RX3 A;  5EAJ A;  4OSG A;  1AI9 A;  4X5I A;  4ELF A;  3F8Y A;  3CD2 A;  1RB2 A;  4LAG X;  1S3W A;  1DDR A;  3SRW X;  1RX1 A;  4XT5 A;  2BLB A;  3EEL A;  1RA8 A;  4M6J A;  1RD7 A;  3KFY A;  4H97 A;  1TDR A;  2ITH A;  7DFR A;  3JVX A;  5HSU A;  1PD8 A;  2CIG A;  2GD9 A;  4DFR A;  4X5G A;  3SA1 A;  3INV A;  3GYF A;  4PTH A;  3FQF A;  2ZZA A;  1AOE A;  3UM5 A;  3QLX A;  3NTZ A;  3VCO A;  3CLB A;  3R33 A;  1DHF A;  3IRM A;  3FRB X;  4M7V A;  3SAI A;  3K74 A;  3S3V A;  3EEK A;  5U27 A;  3SH2 A;  5ECC A;  5DFR A;  3NXO A;  3DAT A;  1LY3 A;  4EIL A;  1LUD A;  3DL5 A;  4XT7 A;  1RX7 A;  4PSY A;  1DR3 A;  4KEB A;  1BZF A;  4Q67 A;  1CZ3 A;  1DR4 A;  1J3I A;  1KLK A;  1QZF A;  1S3U A;  3F0S X;  3NZB X;  2FZH A;  4Q0E A;  1J3J A;  1DR1 A;  2P4G A;  4M6K A;  4KY4 A;  4XE6 X;  1M79 A;  3QL0 A;  3LG4 A;  3EX8 A;  4HOG A;  1E26 A;  4M2X A;  1MVT A;  1RX8 A;  1DR7 A;  1BOZ A;  1D1G A;  3K2H A;  2JYB A;  1DAJ A;  3OCH A;  2INQ A;  2HM9 A;  4HOF A;  4M7U A;  4FGG A;  3FL9 A;  1M7A A;  3UM8 A;  3UM6 A;  3F0U X;  4P3R A;  1RX6 A;  3F0B X;  3QYO A;  4G8Z X;  1DYR A;  1RA2 A;  4X5F A;  1S3V A;  5HT5 A;  3RO9 A;  3FL8 A;  1DYI A;  1IA3 A;  2W9S A;  1DYH A;  3IX9 A;  4H98 A;  4PDJ A;  1DR6 A;  3K45 A;  3QLS A;  5HF0 X;  1DRA A;  1RE7 A;  4H96 A;  3GHW A;  4DP3 A;  3NZA X;  2HQP A;  4G3M A;  5HQZ A;  1RH3 A;  5HVB A;  1DR5 A;  4PTJ A;  1DRF A;  4KY8 A;  4DPH A;  1VJ3 A;  4KBN A;  2BL9 A;  3FS6 A;  2B3Z A;  3TQ8 A;  4XEC X;  3D80 A;  3FYV X;  4XT8 A;  4H95 A;  4NX7 A;  4EIZ A;  8DFR A;  2KGK A;  2XW7 A;  4TU5 X;  2W9H A;  4KM2 A;  3EEJ A;  3DAU A;  4ECK A;  3OAF A;  4P68 A;  5ECX A;  3TQB A;  2C2S A;  1OHJ A;  3FY9 X;  1JOL A;  3NXY A;  4PSS A;  3QLZ A;  3NZC X;  1YHO A;  3I8A X;  2OIP A;  3DL6 A;  3FRA X;  5HPB A;  3NXV A;  1RX4 A;  3JW5 A;  3F0V X;  1ZDR A;  4FGH A;  4IXF X;  1U71 A;  3TQ9 A;  1J3K A;  3NZ9 X;  3GHC A;  5HUI A;  1RA3 A;  5E8Q A;  1DIS A;  2W3B A;  1DRH A;  1VDR A;  2OBC A;  3EIG A;  3IRO A;  1DYJ A;  1RX2 A;  3FRF X;  3QLY A;  3F0Q X;  1DLR A;  3S9U A;  2FZI A;  4DDR A;  3NXX A;  1RG7 A;  3QLW A;  1MVS A;  3NXT A;  1JOM A;  3FYW X;  1DRB A;  5U26 A;  2W3A A;  3ROA A;  3F91 A;  4NX6 A;  2FZJ A;  3IA4 A;  2H2Q A;  4I1N A;  3FQV A;  3KJR A;  3N0H A;  5HF2 X;  3KGY A;  4GH8 A;  1DHJ A;  2ANO A;  2W9T A;  4KNE A;  5HVE A;  5CCC A;  4KD7 A;  4QLG A;  3FRE X;  2QK8 A; 
#chains in the Genus database with same CATH topology
 4KJJ A;  5DXV A;  3RG9 A;  3D84 X;  3M08 A;  3SRQ X;  3IRN A;  3ZPG A;  1RC4 A;  4OR7 A;  4EIG A;  3EEM A;  4XT6 A;  2W3V A;  3SGY A;  6DFR A;  4X5J A;  2W3W A;  1DDS A;  2DRC A;  3FQO A;  3JTW A;  4QLE A;  3K47 A;  1S3Y A;  3QYL A;  1HFQ A;  4ELG A;  4LAE X;  4Q6A A;  1DIU A;  1RF7 A;  4QJC A;  3FQ0 A;  3JWF A;  1IA2 A;  3QGT A;  3S7A A;  3SRS X;  4KAK A;  3CL9 A;  3JW3 A;  3QL3 A;  3NRR A;  3DG8 A;  1RA1 A;  2L28 A;  3JWM A;  4LAH X;  5HI6 A;  4QI9 A;  3FQC A;  4M6L A;  4X5H A;  3JSU A;  2DHF A;  4HA7 A;  1RB3 A;  4KFJ A;  1DG7 A;  1RX9 A;  4QJZ D;  3SA2 A;  2W9G A;  4IXG X;  1KMV A;  3NZD A;  4HA9 A;  3TD8 A;  3FY8 X;  1RX5 A;  4KL9 A;  4FHB A;  3QLR A;  3L3R A;  1DHI A;  3Q1H A;  4LEK X;  3SR5 X;  1PDB A;  2D5N A;  5HT4 A;  2HXV A;  1DR2 A;  2O7P A;  4Q0D A;  1OHK A;  4QHV A;  4KLX A;  4EJ1 A;  4KM0 A;  4ELH A;  2G6V A;  3NU0 A;  3IA5 A;  4DPD A;  1M78 A;  1U70 A;  1DG5 A;  1SEJ A;  2CD2 A;  2ANQ A;  3JWC A;  4KYA A;  5CC9 A;  3FQZ A;  1AO8 A;  2D0K A;  4IXE D;  3M09 A;  3CSE A;  1KMS A;  1RA9 A;  3F8Z A;  3DGA A;  4KJL A;  1DF7 A;  4XRB A;  5JA3 A;  3DRC A;  3KJS A;  2AZN A;  3QFX A;  4PST A;  4I13 A;  3HJ3 A;  3QG2 A;  1U72 A;  1DG8 A;  4XT4 A;  3SRU X;  5JG0 X;  2BLC A;  1IA4 A;  2C2T A;  3NXR A;  4QLF A;  5FDA A;  3KY8 A;  1LY4 A;  2W3M A;  3DFR A;  3HBB A;  3SRR X;  1PD9 A;  1DRE A;  1IA1 A;  5HQY A;  2BLA A;  4G95 A;  3GI2 A;  4KJK A;  1JUV A;  3SQY X;  4ELB A;  3E0B A;  3I3R A;  1CD2 A;  4HOE A;  1HFP A;  4P66 A;  2LF1 A;  4RGC A;  3ZPC A;  3NZ6 X;  3JWK A;  3FRD X;  3F0X X;  4ELE A;  5HSR A;  3GHV A;  1DLS A;  3TQA A;  4P3Q A;  1HFR A;  4CD2 A;  1RX3 A;  5EAJ A;  4OSG A;  1AI9 A;  4X5I A;  4ELF A;  3F8Y A;  3CD2 A;  1RB2 A;  4LAG X;  1S3W A;  1DDR A;  3SRW X;  1RX1 A;  4XT5 A;  2BLB A;  3EEL A;  1RA8 A;  4M6J A;  1RD7 A;  3KFY A;  4H97 A;  1TDR A;  2ITH A;  7DFR A;  3JVX A;  5HSU A;  1PD8 A;  2CIG A;  2GD9 A;  4DFR A;  4X5G A;  3SA1 A;  3INV A;  3GYF A;  4PTH A;  3FQF A;  2ZZA A;  1AOE A;  3UM5 A;  3QLX A;  3NTZ A;  3VCO A;  3CLB A;  3R33 A;  1DHF A;  3IRM A;  3FRB X;  4M7V A;  3SAI A;  3K74 A;  3S3V A;  3EEK A;  5U27 A;  3SH2 A;  5ECC A;  5DFR A;  3NXO A;  3DAT A;  1LY3 A;  4EIL A;  1LUD A;  3DL5 A;  4XT7 A;  1RX7 A;  4PSY A;  1DR3 A;  4KEB A;  1BZF A;  4Q67 A;  1CZ3 A;  1DR4 A;  1J3I A;  1KLK A;  1QZF A;  1S3U A;  3F0S X;  3NZB X;  2FZH A;  4Q0E A;  1J3J A;  1DR1 A;  2P4G A;  4M6K A;  4KY4 A;  4XE6 X;  1M79 A;  3QL0 A;  3LG4 A;  3EX8 A;  4HOG A;  1E26 A;  4M2X A;  1MVT A;  1RX8 A;  1DR7 A;  1BOZ A;  1D1G A;  3K2H A;  2JYB A;  1DAJ A;  3OCH A;  2INQ A;  2HM9 A;  4HOF A;  4M7U A;  4FGG A;  3FL9 A;  1M7A A;  3UM8 A;  3UM6 A;  3F0U X;  4P3R A;  1RX6 A;  3F0B X;  3QYO A;  4G8Z X;  1DYR A;  1RA2 A;  4X5F A;  1S3V A;  5HT5 A;  3RO9 A;  3FL8 A;  1DYI A;  1IA3 A;  2W9S A;  1DYH A;  3IX9 A;  4H98 A;  4PDJ A;  1DR6 A;  3K45 A;  3QLS A;  5HF0 X;  1DRA A;  1RE7 A;  4H96 A;  3GHW A;  4DP3 A;  3NZA X;  2HQP A;  4G3M A;  5HQZ A;  1RH3 A;  5HVB A;  1DR5 A;  4PTJ A;  1DRF A;  4KY8 A;  4DPH A;  1VJ3 A;  4KBN A;  2BL9 A;  3FS6 A;  2B3Z A;  3TQ8 A;  4XEC X;  3D80 A;  3FYV X;  4XT8 A;  4H95 A;  4NX7 A;  4EIZ A;  8DFR A;  2KGK A;  2XW7 A;  4TU5 X;  2W9H A;  4KM2 A;  3EEJ A;  3DAU A;  4ECK A;  3OAF A;  4P68 A;  5ECX A;  3TQB A;  2C2S A;  1OHJ A;  3FY9 X;  1JOL A;  3NXY A;  4PSS A;  3QLZ A;  3NZC X;  1YHO A;  3I8A X;  2OIP A;  3DL6 A;  3FRA X;  5HPB A;  3NXV A;  1RX4 A;  3JW5 A;  3F0V X;  1ZDR A;  4FGH A;  4IXF X;  1U71 A;  3TQ9 A;  1J3K A;  3NZ9 X;  3GHC A;  5HUI A;  1RA3 A;  5E8Q A;  1DIS A;  2W3B A;  1DRH A;  1VDR A;  2OBC A;  3EIG A;  3IRO A;  1DYJ A;  1RX2 A;  3FRF X;  3QLY A;  3F0Q X;  1DLR A;  3S9U A;  2FZI A;  4DDR A;  3NXX A;  1RG7 A;  3QLW A;  1MVS A;  3NXT A;  1JOM A;  3FYW X;  1DRB A;  5U26 A;  2W3A A;  3ROA A;  3F91 A;  4NX6 A;  2FZJ A;  3IA4 A;  2H2Q A;  4I1N A;  3FQV A;  3KJR A;  3N0H A;  5HF2 X;  3KGY A;  4GH8 A;  1DHJ A;  2ANO A;  2W9T A;  4KNE A;  5HVE A;  5CCC A;  4KD7 A;  4QLG A;  3FRE X;  2QK8 A; 
#chains in the Genus database with same CATH homology
 4KJJ A;  5DXV A;  3RG9 A;  3D84 X;  3M08 A;  3SRQ X;  3IRN A;  3ZPG A;  1RC4 A;  4OR7 A;  4EIG A;  3EEM A;  4XT6 A;  2W3V A;  3SGY A;  6DFR A;  4X5J A;  2W3W A;  1DDS A;  2DRC A;  3FQO A;  3JTW A;  4QLE A;  3K47 A;  1S3Y A;  3QYL A;  1HFQ A;  4ELG A;  4LAE X;  4Q6A A;  1DIU A;  1RF7 A;  4QJC A;  3FQ0 A;  3JWF A;  1IA2 A;  3QGT A;  3S7A A;  3SRS X;  4KAK A;  3CL9 A;  3JW3 A;  3QL3 A;  3NRR A;  3DG8 A;  1RA1 A;  2L28 A;  3JWM A;  4LAH X;  5HI6 A;  4QI9 A;  3FQC A;  4M6L A;  4X5H A;  3JSU A;  2DHF A;  4HA7 A;  1RB3 A;  4KFJ A;  1DG7 A;  1RX9 A;  4QJZ D;  3SA2 A;  2W9G A;  4IXG X;  1KMV A;  3NZD A;  4HA9 A;  3TD8 A;  3FY8 X;  1RX5 A;  4KL9 A;  4FHB A;  3QLR A;  3L3R A;  1DHI A;  3Q1H A;  4LEK X;  3SR5 X;  1PDB A;  2D5N A;  5HT4 A;  2HXV A;  1DR2 A;  2O7P A;  4Q0D A;  1OHK A;  4QHV A;  4KLX A;  4EJ1 A;  4KM0 A;  4ELH A;  2G6V A;  3NU0 A;  3IA5 A;  4DPD A;  1M78 A;  1U70 A;  1DG5 A;  1SEJ A;  2CD2 A;  2ANQ A;  3JWC A;  4KYA A;  5CC9 A;  3FQZ A;  1AO8 A;  2D0K A;  4IXE D;  3M09 A;  3CSE A;  1KMS A;  1RA9 A;  3F8Z A;  3DGA A;  4KJL A;  1DF7 A;  4XRB A;  5JA3 A;  3DRC A;  3KJS A;  2AZN A;  3QFX A;  4PST A;  4I13 A;  3HJ3 A;  3QG2 A;  1U72 A;  1DG8 A;  4XT4 A;  3SRU X;  5JG0 X;  2BLC A;  1IA4 A;  2C2T A;  3NXR A;  4QLF A;  5FDA A;  3KY8 A;  1LY4 A;  2W3M A;  3DFR A;  3HBB A;  3SRR X;  1PD9 A;  1DRE A;  1IA1 A;  5HQY A;  2BLA A;  4G95 A;  3GI2 A;  4KJK A;  1JUV A;  3SQY X;  4ELB A;  3E0B A;  3I3R A;  1CD2 A;  4HOE A;  1HFP A;  4P66 A;  2LF1 A;  4RGC A;  3ZPC A;  3NZ6 X;  3JWK A;  3FRD X;  3F0X X;  4ELE A;  5HSR A;  3GHV A;  1DLS A;  3TQA A;  4P3Q A;  1HFR A;  4CD2 A;  1RX3 A;  5EAJ A;  4OSG A;  1AI9 A;  4X5I A;  4ELF A;  3F8Y A;  3CD2 A;  1RB2 A;  4LAG X;  1S3W A;  1DDR A;  3SRW X;  1RX1 A;  4XT5 A;  2BLB A;  3EEL A;  1RA8 A;  4M6J A;  1RD7 A;  3KFY A;  4H97 A;  1TDR A;  2ITH A;  7DFR A;  3JVX A;  5HSU A;  1PD8 A;  2CIG A;  2GD9 A;  4DFR A;  4X5G A;  3SA1 A;  3INV A;  3GYF A;  4PTH A;  3FQF A;  2ZZA A;  1AOE A;  3UM5 A;  3QLX A;  3NTZ A;  3VCO A;  3CLB A;  3R33 A;  1DHF A;  3IRM A;  3FRB X;  4M7V A;  3SAI A;  3K74 A;  3S3V A;  3EEK A;  5U27 A;  3SH2 A;  5ECC A;  5DFR A;  3NXO A;  3DAT A;  1LY3 A;  4EIL A;  1LUD A;  3DL5 A;  4XT7 A;  1RX7 A;  4PSY A;  1DR3 A;  4KEB A;  1BZF A;  4Q67 A;  1CZ3 A;  1DR4 A;  1J3I A;  1KLK A;  1QZF A;  1S3U A;  3F0S X;  3NZB X;  2FZH A;  4Q0E A;  1J3J A;  1DR1 A;  2P4G A;  4M6K A;  4KY4 A;  4XE6 X;  1M79 A;  3QL0 A;  3LG4 A;  3EX8 A;  4HOG A;  1E26 A;  4M2X A;  1MVT A;  1RX8 A;  1DR7 A;  1BOZ A;  1D1G A;  3K2H A;  2JYB A;  1DAJ A;  3OCH A;  2INQ A;  2HM9 A;  4HOF A;  4M7U A;  4FGG A;  3FL9 A;  1M7A A;  3UM8 A;  3UM6 A;  3F0U X;  4P3R A;  1RX6 A;  3F0B X;  3QYO A;  4G8Z X;  1DYR A;  1RA2 A;  4X5F A;  1S3V A;  5HT5 A;  3RO9 A;  3FL8 A;  1DYI A;  1IA3 A;  2W9S A;  1DYH A;  3IX9 A;  4H98 A;  4PDJ A;  1DR6 A;  3K45 A;  3QLS A;  5HF0 X;  1DRA A;  1RE7 A;  4H96 A;  3GHW A;  4DP3 A;  3NZA X;  2HQP A;  4G3M A;  5HQZ A;  1RH3 A;  5HVB A;  1DR5 A;  4PTJ A;  1DRF A;  4KY8 A;  4DPH A;  1VJ3 A;  4KBN A;  2BL9 A;  3FS6 A;  2B3Z A;  3TQ8 A;  4XEC X;  3D80 A;  3FYV X;  4XT8 A;  4H95 A;  4NX7 A;  4EIZ A;  8DFR A;  2KGK A;  2XW7 A;  4TU5 X;  2W9H A;  4KM2 A;  3EEJ A;  3DAU A;  4ECK A;  3OAF A;  4P68 A;  5ECX A;  3TQB A;  2C2S A;  1OHJ A;  3FY9 X;  1JOL A;  3NXY A;  4PSS A;  3QLZ A;  3NZC X;  1YHO A;  3I8A X;  2OIP A;  3DL6 A;  3FRA X;  5HPB A;  3NXV A;  1RX4 A;  3JW5 A;  3F0V X;  1ZDR A;  4FGH A;  4IXF X;  1U71 A;  3TQ9 A;  1J3K A;  3NZ9 X;  3GHC A;  5HUI A;  1RA3 A;  5E8Q A;  1DIS A;  2W3B A;  1DRH A;  1VDR A;  2OBC A;  3EIG A;  3IRO A;  1DYJ A;  1RX2 A;  3FRF X;  3QLY A;  3F0Q X;  1DLR A;  3S9U A;  2FZI A;  4DDR A;  3NXX A;  1RG7 A;  3QLW A;  1MVS A;  3NXT A;  1JOM A;  3FYW X;  1DRB A;  5U26 A;  2W3A A;  3ROA A;  3F91 A;  4NX6 A;  2FZJ A;  3IA4 A;  2H2Q A;  4I1N A;  3FQV A;  3KJR A;  3N0H A;  5HF2 X;  3KGY A;  4GH8 A;  1DHJ A;  2ANO A;  2W9T A;  4KNE A;  5HVE A;  5CCC A;  4KD7 A;  4QLG A;  3FRE X;  2QK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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