1J3JA

Double mutant (c59r+s108n) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with pyrimethamine, nadph, and dump
Total Genus 66
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
231
structure length
221
Chain Sequence
MMEQVCDVFDIYAICACCKVESKNEGKKNEVFNNYTFRGLGNKGVLPWKCNSLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKETKKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFIIGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTNN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Insights into antifolate resistance from malarial DHFR-TS structures.
pubmed doi rcsb
molecule tags Oxidoreductase, transferase
source organism Plasmodium falciparum
molecule keywords Bifunctional dihydrofolate reductase-thymidylate synthase
total genus 66
structure length 221
sequence length 231
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2003-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1j3jA00
5CCCA 4EJ1A 2G6VA 4I1NA 3S7AA 1M79A 1DYHA 4PSSA 3DGAA 3F0XX 3QFXA 5HT5A 1BOZA 3JWCA 5HVBA 3DATA 3RG9A 1RC4A 3UM8A 4QLGA 2W3MA 2ITHA 3FRFX 4DPDA 1RX9A 1RX1A 3FRAX 1RX6A 2ANQA 3SR5X 3F8YA 1JOLA 3IROA 4KL9A 4H95A 1DIUA 1E26A 3QL3A 1M7AA 1U72A 4H96A 2CD2A 4HOEA 4IXGX 4DPHA 3FREX 3QGTA 1S3UA 4XRBA 4X5FA 3TQ8A 1S3VA 1DLSA 3QYOA 4KJLA 3FQOA 3RO9A 5HF0X 4H98A 5HI6A 4KFJA 3SRQX 2L28A 1RB3A 1RX7A 2BL9A 4HA7A 3GHWA 4Q0EA 1AOEA 4KAKA 4LEKX 3EEJA 4Q67A 3JW5A 3NZ9X 5HT4A 4CD2A 1IA4A 4Q0DA 4QHVA 1AO8A 3DRCA 4HA9A 4XT6A 1J3JA 3NXTA 1RA8A 1DR2A 4P3QA 3M08A 1DF7A 3NXYA 1DR5A 3INVA 3SRUX 4QJCA 3DG8A 6DFRA 1MVTA 3NRRA 5ECCA 2W3VA 5DFRA 2W9SA 4Q6AA 3SRRX 1DDSA 1ZDRA 3SGYA 3QL0A 4XT7A 2W9TA 3FY9X 2D0KA 4I13A 4LAHX 4ECKA 4DP3A 1KMVA 2OIPA 3QLSA 4KLXA 4HOFA 1HFQA 1PD8A 3FQFA 5JA3A 1IA1A 3NZAX 3R33A 1DLRA 4IXED 3FQ0A 4XE6X 4OR7A 3GI2A 1DR4A 1IA2A 5HSUA 1KMSA 4X5JA 3FQVA 5JG0X 3JSUA 4EIGA 1S3WA 3UM6A 3CSEA 1RX2A 3IRNA 1RE7A 3JW3A 1RD7A 1DRHA 5U26A 5HVEA 3K74A 3F0VX 1DG8A 3QLXA 2BLBA 2INQA 2W9HA 4EILA 3EIGA 4OSGA 2FZHA 3FQZA 4M6KA 3JWKA 4ELEA 2HM9A 3JWFA 3NZBX 3SA2A 3KFYA 2W9GA 3K2HA 1RX3A 5HF2X 2BLCA 2FZJA 4KNEA 3QLRA 1RX5A 2C2SA 5CC9A 3SAIA 1DISA 2AZNA 3HJ3A 3FRDX 4KJJA 1DG7A 1VJ3A 2OBCA 1RX8A 2KGKA 3QG2A 3QLYA 3ZPGA 5HQYA 1HFRA 3FL8A 3EELA 3CL9A 3SRSX 3F0UX 4KY8A 2GD9A 4G95A 3SA1A 8DFRA 1LUDA 2W3WA 5HSRA 4FHBA 1RX4A 2JYBA 3QYLA 1MVSA 3FS6A 1DRFA 1RA3A 4TU5X 3FL9A 1DDRA 4ELFA 1DRAA 5FDAA 1HFPA 3IA5A 3QLZA 3NXOA 1QZFA 4FGGA 4X5HA 1DR3A 2HQPA 4QLFA 4PTHA 3F0BX 4ELBA 4ELHA 3DL5A 1DRBA 2W3AA 3JVXA 4KM2A 3KY8A 3SRWX 3I8AX 2HXVA 1S3YA 1JOMA 5HQZA 4P68A 3OCHA 3N0HA 4P3RA 4XT8A 2LF1A 1JUVA 4ELGA 1OHKA 1DHIA 1SEJA 1LY3A 4FGHA 4RGCA 3KGYA 1AI9A 1J3IA 3F0SX 1DAJA 5ECXA 4XT5A 5HUIA 3Q1HA 1IA3A 1RA2A 4M7VA 1TDRA 2B3ZA 3L3RA 4GH8A 3FYVX 2P4GA 4QJZD 2QK8A 4M7UA 1CZ3A 1VDRA 1RA1A 4P66A 3EEMA 3GHVA 4QLEA 4G3MA 3SH2A 1DR1A 4LAEX 2BLAA 3SQYX 2O7PA 4KYAA 4KD7A 3F91A 5E8QA 3FYWX 3D80A 4KY4A 1D1GA 1DYRA 4H97A 4M6JA 4G8ZX 3QLWA 1DR7A 3JTWA 4KM0A 4NX6A 3GHCA 1U71A 2ZZAA 3KJSA 3IX9A 3OAFA 1YHOA 2FZIA 3D84X 2D5NA 3F8ZA 3UM5A 1OHJA 3DL6A 3NXRA 1KLKA 5EAJA 3HBBA 1LY4A 1DYIA 3JWMA 4PTJA 1U70A 2CIGA 3LG4A 5U27A 7DFRA 1CD2A 5HPBA 1J3KA 3EX8A 3DAUA 4X5IA 3VCOA 4QI9A 1BZFA 2XW7A 3NZ6X 3F0QX 3TQAA 3S3VA 2W3BA 3NZDA 5DXVA 3S9UA 4KBNA 4KEBA 1PD9A 1DHJA 2DRCA 3NXXA 3IA4A 1PDBA 4IXFX 2ANOA 3ZPCA 2DHFA 3K47A 2H2QA 3EEKA 4PSYA 4EIZA 4HOGA 3KJRA 4X5GA 4XT4A 4PDJA 3NZCX 3FRBX 1RB2A 3E0BA 4DDRA 1DR6A 3I3RA 3CD2A 3FQCA 2C2TA 4DFRA 1DG5A 3NU0A 3ROAA 1M78A 3CLBA 3TD8A 3IRMA 3NTZA 1DHFA 3GYFA 4LAGX 3TQ9A 4NX7A 4M2XA 1RH3A 3K45A 4M6LA 1RG7A 1DREA 3DFRA 3M09A 4KJKA 4PSTA 3FY8X 3TQBA 1RA9A 3NXVA 1DYJA 1RF7A 4XECX
chains in the Genus database with same CATH superfamily
5CCCA 4EJ1A 2G6VA 4I1NA 3S7AA 1M79A 1DYHA 4PSSA 3DGAA 3F0XX 3QFXA 5HT5A 1BOZA 3JWCA 5HVBA 3DATA 3RG9A 1RC4A 3UM8A 4QLGA 2W3MA 2ITHA 3FRFX 4DPDA 1RX9A 1RX1A 3FRAX 1RX6A 2ANQA 3SR5X 3F8YA 1JOLA 3IROA 4KL9A 4H95A 1DIUA 1E26A 3QL3A 1M7AA 1U72A 4H96A 2CD2A 4HOEA 4IXGX 4DPHA 3FREX 3QGTA 1S3UA 4XRBA 4X5FA 3TQ8A 1S3VA 1DLSA 3QYOA 4KJLA 3FQOA 3RO9A 5HF0X 4H98A 5HI6A 4KFJA 3SRQX 2L28A 1RB3A 1RX7A 2BL9A 4HA7A 3GHWA 4Q0EA 1AOEA 4KAKA 4LEKX 3EEJA 4Q67A 3JW5A 3NZ9X 5HT4A 4CD2A 1IA4A 4Q0DA 4QHVA 1AO8A 3DRCA 4HA9A 4XT6A 1J3JA 3NXTA 1RA8A 1DR2A 4P3QA 3M08A 1DF7A 3NXYA 1DR5A 3INVA 3SRUX 4QJCA 3DG8A 6DFRA 1MVTA 3NRRA 5ECCA 2W3VA 5DFRA 2W9SA 4Q6AA 3SRRX 1DDSA 1ZDRA 3SGYA 3QL0A 4XT7A 2W9TA 3FY9X 2D0KA 4I13A 4LAHX 4ECKA 4DP3A 1KMVA 2OIPA 3QLSA 4KLXA 4HOFA 1HFQA 1PD8A 3FQFA 5JA3A 1IA1A 3NZAX 3R33A 1DLRA 4IXED 3FQ0A 4XE6X 4OR7A 3GI2A 1DR4A 1IA2A 5HSUA 1KMSA 4X5JA 3FQVA 5JG0X 3JSUA 4EIGA 1S3WA 3UM6A 3CSEA 1RX2A 3IRNA 1RE7A 3JW3A 1RD7A 1DRHA 5U26A 5HVEA 3K74A 3F0VX 1DG8A 3QLXA 2BLBA 2INQA 2W9HA 4EILA 3EIGA 4OSGA 2FZHA 3FQZA 4M6KA 3JWKA 4ELEA 2HM9A 3JWFA 3NZBX 3SA2A 3KFYA 2W9GA 3K2HA 1RX3A 5HF2X 2BLCA 2FZJA 4KNEA 3QLRA 1RX5A 2C2SA 5CC9A 3SAIA 1DISA 2AZNA 3HJ3A 3FRDX 4KJJA 1DG7A 1VJ3A 2OBCA 1RX8A 2KGKA 3QG2A 3QLYA 3ZPGA 5HQYA 1HFRA 3FL8A 3EELA 3CL9A 3SRSX 3F0UX 4KY8A 2GD9A 4G95A 3SA1A 8DFRA 1LUDA 2W3WA 5HSRA 4FHBA 1RX4A 2JYBA 3QYLA 1MVSA 3FS6A 1DRFA 1RA3A 4TU5X 3FL9A 1DDRA 4ELFA 1DRAA 5FDAA 1HFPA 3IA5A 3QLZA 3NXOA 1QZFA 4FGGA 4X5HA 1DR3A 2HQPA 4QLFA 4PTHA 3F0BX 4ELBA 4ELHA 3DL5A 1DRBA 2W3AA 3JVXA 4KM2A 3KY8A 3SRWX 3I8AX 2HXVA 1S3YA 1JOMA 5HQZA 4P68A 3OCHA 3N0HA 4P3RA 4XT8A 2LF1A 1JUVA 4ELGA 1OHKA 1DHIA 1SEJA 1LY3A 4FGHA 4RGCA 3KGYA 1AI9A 1J3IA 3F0SX 1DAJA 5ECXA 4XT5A 5HUIA 3Q1HA 1IA3A 1RA2A 4M7VA 1TDRA 2B3ZA 3L3RA 4GH8A 3FYVX 2P4GA 4QJZD 2QK8A 4M7UA 1CZ3A 1VDRA 1RA1A 4P66A 3EEMA 3GHVA 4QLEA 4G3MA 3SH2A 1DR1A 4LAEX 2BLAA 3SQYX 2O7PA 4KYAA 4KD7A 3F91A 5E8QA 3FYWX 3D80A 4KY4A 1D1GA 1DYRA 4H97A 4M6JA 4G8ZX 3QLWA 1DR7A 3JTWA 4KM0A 4NX6A 3GHCA 1U71A 2ZZAA 3KJSA 3IX9A 3OAFA 1YHOA 2FZIA 3D84X 2D5NA 3F8ZA 3UM5A 1OHJA 3DL6A 3NXRA 1KLKA 5EAJA 3HBBA 1LY4A 1DYIA 3JWMA 4PTJA 1U70A 2CIGA 3LG4A 5U27A 7DFRA 1CD2A 5HPBA 1J3KA 3EX8A 3DAUA 4X5IA 3VCOA 4QI9A 1BZFA 2XW7A 3NZ6X 3F0QX 3TQAA 3S3VA 2W3BA 3NZDA 5DXVA 3S9UA 4KBNA 4KEBA 1PD9A 1DHJA 2DRCA 3NXXA 3IA4A 1PDBA 4IXFX 2ANOA 3ZPCA 2DHFA 3K47A 2H2QA 3EEKA 4PSYA 4EIZA 4HOGA 3KJRA 4X5GA 4XT4A 4PDJA 3NZCX 3FRBX 1RB2A 3E0BA 4DDRA 1DR6A 3I3RA 3CD2A 3FQCA 2C2TA 4DFRA 1DG5A 3NU0A 3ROAA 1M78A 3CLBA 3TD8A 3IRMA 3NTZA 1DHFA 3GYFA 4LAGX 3TQ9A 4NX7A 4M2XA 1RH3A 3K45A 4M6LA 1RG7A 1DREA 3DFRA 3M09A 4KJKA 4PSTA 3FY8X 3TQBA 1RA9A 3NXVA 1DYJA 1RF7A 4XECX
chains in the Genus database with same CATH topology
5CCCA 4EJ1A 2G6VA 4I1NA 3S7AA 1M79A 1DYHA 4PSSA 3DGAA 3F0XX 3QFXA 5HT5A 1BOZA 3JWCA 5HVBA 3DATA 3RG9A 1RC4A 3UM8A 4QLGA 2W3MA 2ITHA 3FRFX 4DPDA 1RX9A 1RX1A 3FRAX 1RX6A 2ANQA 3SR5X 3F8YA 1JOLA 3IROA 4KL9A 4H95A 1DIUA 1E26A 3QL3A 1M7AA 1U72A 4H96A 2CD2A 4HOEA 4IXGX 4DPHA 3FREX 3QGTA 1S3UA 4XRBA 4X5FA 3TQ8A 1S3VA 1DLSA 3QYOA 4KJLA 3FQOA 3RO9A 5HF0X 4H98A 5HI6A 4KFJA 3SRQX 2L28A 1RB3A 1RX7A 2BL9A 4HA7A 3GHWA 4Q0EA 1AOEA 4KAKA 4LEKX 3EEJA 4Q67A 3JW5A 3NZ9X 5HT4A 4CD2A 1IA4A 4Q0DA 4QHVA 1AO8A 3DRCA 4HA9A 4XT6A 1J3JA 3NXTA 1RA8A 1DR2A 4P3QA 3M08A 1DF7A 3NXYA 1DR5A 3INVA 3SRUX 4QJCA 3DG8A 6DFRA 1MVTA 3NRRA 5ECCA 2W3VA 5DFRA 2W9SA 4Q6AA 3SRRX 1DDSA 1ZDRA 3SGYA 3QL0A 4XT7A 2W9TA 3FY9X 2D0KA 4I13A 4LAHX 4ECKA 4DP3A 1KMVA 2OIPA 3QLSA 4KLXA 4HOFA 1HFQA 1PD8A 3FQFA 5JA3A 1IA1A 3NZAX 3R33A 1DLRA 4IXED 3FQ0A 4XE6X 4OR7A 3GI2A 1DR4A 1IA2A 5HSUA 1KMSA 4X5JA 3FQVA 5JG0X 3JSUA 4EIGA 1S3WA 3UM6A 3CSEA 1RX2A 3IRNA 1RE7A 3JW3A 1RD7A 1DRHA 5U26A 5HVEA 3K74A 3F0VX 1DG8A 3QLXA 2BLBA 2INQA 2W9HA 4EILA 3EIGA 4OSGA 2FZHA 3FQZA 4M6KA 3JWKA 4ELEA 2HM9A 3JWFA 3NZBX 3SA2A 3KFYA 2W9GA 3K2HA 1RX3A 5HF2X 2BLCA 2FZJA 4KNEA 3QLRA 1RX5A 2C2SA 5CC9A 3SAIA 1DISA 2AZNA 3HJ3A 3FRDX 4KJJA 1DG7A 1VJ3A 2OBCA 1RX8A 2KGKA 3QG2A 3QLYA 3ZPGA 5HQYA 1HFRA 3FL8A 3EELA 3CL9A 3SRSX 3F0UX 4KY8A 2GD9A 4G95A 3SA1A 8DFRA 1LUDA 2W3WA 5HSRA 4FHBA 1RX4A 2JYBA 3QYLA 1MVSA 3FS6A 1DRFA 1RA3A 4TU5X 3FL9A 1DDRA 4ELFA 1DRAA 5FDAA 1HFPA 3IA5A 3QLZA 3NXOA 1QZFA 4FGGA 4X5HA 1DR3A 2HQPA 4QLFA 4PTHA 3F0BX 4ELBA 4ELHA 3DL5A 1DRBA 2W3AA 3JVXA 4KM2A 3KY8A 3SRWX 3I8AX 2HXVA 1S3YA 1JOMA 5HQZA 4P68A 3OCHA 3N0HA 4P3RA 4XT8A 2LF1A 1JUVA 4ELGA 1OHKA 1DHIA 1SEJA 1LY3A 4FGHA 4RGCA 3KGYA 1AI9A 1J3IA 3F0SX 1DAJA 5ECXA 4XT5A 5HUIA 3Q1HA 1IA3A 1RA2A 4M7VA 1TDRA 2B3ZA 3L3RA 4GH8A 3FYVX 2P4GA 4QJZD 2QK8A 4M7UA 1CZ3A 1VDRA 1RA1A 4P66A 3EEMA 3GHVA 4QLEA 4G3MA 3SH2A 1DR1A 4LAEX 2BLAA 3SQYX 2O7PA 4KYAA 4KD7A 3F91A 5E8QA 3FYWX 3D80A 4KY4A 1D1GA 1DYRA 4H97A 4M6JA 4G8ZX 3QLWA 1DR7A 3JTWA 4KM0A 4NX6A 3GHCA 1U71A 2ZZAA 3KJSA 3IX9A 3OAFA 1YHOA 2FZIA 3D84X 2D5NA 3F8ZA 3UM5A 1OHJA 3DL6A 3NXRA 1KLKA 5EAJA 3HBBA 1LY4A 1DYIA 3JWMA 4PTJA 1U70A 2CIGA 3LG4A 5U27A 7DFRA 1CD2A 5HPBA 1J3KA 3EX8A 3DAUA 4X5IA 3VCOA 4QI9A 1BZFA 2XW7A 3NZ6X 3F0QX 3TQAA 3S3VA 2W3BA 3NZDA 5DXVA 3S9UA 4KBNA 4KEBA 1PD9A 1DHJA 2DRCA 3NXXA 3IA4A 1PDBA 4IXFX 2ANOA 3ZPCA 2DHFA 3K47A 2H2QA 3EEKA 4PSYA 4EIZA 4HOGA 3KJRA 4X5GA 4XT4A 4PDJA 3NZCX 3FRBX 1RB2A 3E0BA 4DDRA 1DR6A 3I3RA 3CD2A 3FQCA 2C2TA 4DFRA 1DG5A 3NU0A 3ROAA 1M78A 3CLBA 3TD8A 3IRMA 3NTZA 1DHFA 3GYFA 4LAGX 3TQ9A 4NX7A 4M2XA 1RH3A 3K45A 4M6LA 1RG7A 1DREA 3DFRA 3M09A 4KJKA 4PSTA 3FY8X 3TQBA 1RA9A 3NXVA 1DYJA 1RF7A 4XECX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CCC A;  4EJ1 A;  2G6V A;  4I1N A;  3S7A A;  1M79 A;  1DYH A;  4PSS A;  3DGA A;  3F0X X;  3QFX A;  5HT5 A;  1BOZ A;  3JWC A;  5HVB A;  3DAT A;  3RG9 A;  1RC4 A;  3UM8 A;  4QLG A;  2W3M A;  2ITH A;  3FRF X;  4DPD A;  1RX9 A;  1RX1 A;  3FRA X;  1RX6 A;  2ANQ A;  3SR5 X;  3F8Y A;  1JOL A;  3IRO A;  4KL9 A;  4H95 A;  1DIU A;  1E26 A;  3QL3 A;  1M7A A;  1U72 A;  4H96 A;  2CD2 A;  4HOE A;  4IXG X;  4DPH A;  3FRE X;  3QGT A;  1S3U A;  4XRB A;  4X5F A;  3TQ8 A;  1S3V A;  1DLS A;  3QYO A;  4KJL A;  3FQO A;  3RO9 A;  5HF0 X;  4H98 A;  5HI6 A;  4KFJ A;  3SRQ X;  2L28 A;  1RB3 A;  1RX7 A;  2BL9 A;  4HA7 A;  3GHW A;  4Q0E A;  1AOE A;  4KAK A;  4LEK X;  3EEJ A;  4Q67 A;  3JW5 A;  3NZ9 X;  5HT4 A;  4CD2 A;  1IA4 A;  4Q0D A;  4QHV A;  1AO8 A;  3DRC A;  4HA9 A;  4XT6 A;  1J3J A;  3NXT A;  1RA8 A;  1DR2 A;  4P3Q A;  3M08 A;  1DF7 A;  3NXY A;  1DR5 A;  3INV A;  3SRU X;  4QJC A;  3DG8 A;  6DFR A;  1MVT A;  3NRR A;  5ECC A;  2W3V A;  5DFR A;  2W9S A;  4Q6A A;  3SRR X;  1DDS A;  1ZDR A;  3SGY A;  3QL0 A;  4XT7 A;  2W9T A;  3FY9 X;  2D0K A;  4I13 A;  4LAH X;  4ECK A;  4DP3 A;  1KMV A;  2OIP A;  3QLS A;  4KLX A;  4HOF A;  1HFQ A;  1PD8 A;  3FQF A;  5JA3 A;  1IA1 A;  3NZA X;  3R33 A;  1DLR A;  4IXE D;  3FQ0 A;  4XE6 X;  4OR7 A;  3GI2 A;  1DR4 A;  1IA2 A;  5HSU A;  1KMS A;  4X5J A;  3FQV A;  5JG0 X;  3JSU A;  4EIG A;  1S3W A;  3UM6 A;  3CSE A;  1RX2 A;  3IRN A;  1RE7 A;  3JW3 A;  1RD7 A;  1DRH A;  5U26 A;  5HVE A;  3K74 A;  3F0V X;  1DG8 A;  3QLX A;  2BLB A;  2INQ A;  2W9H A;  4EIL A;  3EIG A;  4OSG A;  2FZH A;  3FQZ A;  4M6K A;  3JWK A;  4ELE A;  2HM9 A;  3JWF A;  3NZB X;  3SA2 A;  3KFY A;  2W9G A;  3K2H A;  1RX3 A;  5HF2 X;  2BLC A;  2FZJ A;  4KNE A;  3QLR A;  1RX5 A;  2C2S A;  5CC9 A;  3SAI A;  1DIS A;  2AZN A;  3HJ3 A;  3FRD X;  4KJJ A;  1DG7 A;  1VJ3 A;  2OBC A;  1RX8 A;  2KGK A;  3QG2 A;  3QLY A;  3ZPG A;  5HQY A;  1HFR A;  3FL8 A;  3EEL A;  3CL9 A;  3SRS X;  3F0U X;  4KY8 A;  2GD9 A;  4G95 A;  3SA1 A;  8DFR A;  1LUD A;  2W3W A;  5HSR A;  4FHB A;  1RX4 A;  2JYB A;  3QYL A;  1MVS A;  3FS6 A;  1DRF A;  1RA3 A;  4TU5 X;  3FL9 A;  1DDR A;  4ELF A;  1DRA A;  5FDA A;  1HFP A;  3IA5 A;  3QLZ A;  3NXO A;  1QZF A;  4FGG A;  4X5H A;  1DR3 A;  2HQP A;  4QLF A;  4PTH A;  3F0B X;  4ELB A;  4ELH A;  3DL5 A;  1DRB A;  2W3A A;  3JVX A;  4KM2 A;  3KY8 A;  3SRW X;  3I8A X;  2HXV A;  1S3Y A;  1JOM A;  5HQZ A;  4P68 A;  3OCH A;  3N0H A;  4P3R A;  4XT8 A;  2LF1 A;  1JUV A;  4ELG A;  1OHK A;  1DHI A;  1SEJ A;  1LY3 A;  4FGH A;  4RGC A;  3KGY A;  1AI9 A;  1J3I A;  3F0S X;  1DAJ A;  5ECX A;  4XT5 A;  5HUI A;  3Q1H A;  1IA3 A;  1RA2 A;  4M7V A;  1TDR A;  2B3Z A;  3L3R A;  4GH8 A;  3FYV X;  2P4G A;  4QJZ D;  2QK8 A;  4M7U A;  1CZ3 A;  1VDR A;  1RA1 A;  4P66 A;  3EEM A;  3GHV A;  4QLE A;  4G3M A;  3SH2 A;  1DR1 A;  4LAE X;  2BLA A;  3SQY X;  2O7P A;  4KYA A;  4KD7 A;  3F91 A;  5E8Q A;  3FYW X;  3D80 A;  4KY4 A;  1D1G A;  1DYR A;  4H97 A;  4M6J A;  4G8Z X;  3QLW A;  1DR7 A;  3JTW A;  4KM0 A;  4NX6 A;  3GHC A;  1U71 A;  2ZZA A;  3KJS A;  3IX9 A;  3OAF A;  1YHO A;  2FZI A;  3D84 X;  2D5N A;  3F8Z A;  3UM5 A;  1OHJ A;  3DL6 A;  3NXR A;  1KLK A;  5EAJ A;  3HBB A;  1LY4 A;  1DYI A;  3JWM A;  4PTJ A;  1U70 A;  2CIG A;  3LG4 A;  5U27 A;  7DFR A;  1CD2 A;  5HPB A;  1J3K A;  3EX8 A;  3DAU A;  4X5I A;  3VCO A;  4QI9 A;  1BZF A;  2XW7 A;  3NZ6 X;  3F0Q X;  3TQA A;  3S3V A;  2W3B A;  3NZD A;  5DXV A;  3S9U A;  4KBN A;  4KEB A;  1PD9 A;  1DHJ A;  2DRC A;  3NXX A;  3IA4 A;  1PDB A;  4IXF X;  2ANO A;  3ZPC A;  2DHF A;  3K47 A;  2H2Q A;  3EEK A;  4PSY A;  4EIZ A;  4HOG A;  3KJR A;  4X5G A;  4XT4 A;  4PDJ A;  3NZC X;  3FRB X;  1RB2 A;  3E0B A;  4DDR A;  1DR6 A;  3I3R A;  3CD2 A;  3FQC A;  2C2T A;  4DFR A;  1DG5 A;  3NU0 A;  3ROA A;  1M78 A;  3CLB A;  3TD8 A;  3IRM A;  3NTZ A;  1DHF A;  3GYF A;  4LAG X;  3TQ9 A;  4NX7 A;  4M2X A;  1RH3 A;  3K45 A;  4M6L A;  1RG7 A;  1DRE A;  3DFR A;  3M09 A;  4KJK A;  4PST A;  3FY8 X;  3TQB A;  1RA9 A;  3NXV A;  1DYJ A;  1RF7 A;  4XEC X; 
#chains in the Genus database with same CATH topology
 5CCC A;  4EJ1 A;  2G6V A;  4I1N A;  3S7A A;  1M79 A;  1DYH A;  4PSS A;  3DGA A;  3F0X X;  3QFX A;  5HT5 A;  1BOZ A;  3JWC A;  5HVB A;  3DAT A;  3RG9 A;  1RC4 A;  3UM8 A;  4QLG A;  2W3M A;  2ITH A;  3FRF X;  4DPD A;  1RX9 A;  1RX1 A;  3FRA X;  1RX6 A;  2ANQ A;  3SR5 X;  3F8Y A;  1JOL A;  3IRO A;  4KL9 A;  4H95 A;  1DIU A;  1E26 A;  3QL3 A;  1M7A A;  1U72 A;  4H96 A;  2CD2 A;  4HOE A;  4IXG X;  4DPH A;  3FRE X;  3QGT A;  1S3U A;  4XRB A;  4X5F A;  3TQ8 A;  1S3V A;  1DLS A;  3QYO A;  4KJL A;  3FQO A;  3RO9 A;  5HF0 X;  4H98 A;  5HI6 A;  4KFJ A;  3SRQ X;  2L28 A;  1RB3 A;  1RX7 A;  2BL9 A;  4HA7 A;  3GHW A;  4Q0E A;  1AOE A;  4KAK A;  4LEK X;  3EEJ A;  4Q67 A;  3JW5 A;  3NZ9 X;  5HT4 A;  4CD2 A;  1IA4 A;  4Q0D A;  4QHV A;  1AO8 A;  3DRC A;  4HA9 A;  4XT6 A;  1J3J A;  3NXT A;  1RA8 A;  1DR2 A;  4P3Q A;  3M08 A;  1DF7 A;  3NXY A;  1DR5 A;  3INV A;  3SRU X;  4QJC A;  3DG8 A;  6DFR A;  1MVT A;  3NRR A;  5ECC A;  2W3V A;  5DFR A;  2W9S A;  4Q6A A;  3SRR X;  1DDS A;  1ZDR A;  3SGY A;  3QL0 A;  4XT7 A;  2W9T A;  3FY9 X;  2D0K A;  4I13 A;  4LAH X;  4ECK A;  4DP3 A;  1KMV A;  2OIP A;  3QLS A;  4KLX A;  4HOF A;  1HFQ A;  1PD8 A;  3FQF A;  5JA3 A;  1IA1 A;  3NZA X;  3R33 A;  1DLR A;  4IXE D;  3FQ0 A;  4XE6 X;  4OR7 A;  3GI2 A;  1DR4 A;  1IA2 A;  5HSU A;  1KMS A;  4X5J A;  3FQV A;  5JG0 X;  3JSU A;  4EIG A;  1S3W A;  3UM6 A;  3CSE A;  1RX2 A;  3IRN A;  1RE7 A;  3JW3 A;  1RD7 A;  1DRH A;  5U26 A;  5HVE A;  3K74 A;  3F0V X;  1DG8 A;  3QLX A;  2BLB A;  2INQ A;  2W9H A;  4EIL A;  3EIG A;  4OSG A;  2FZH A;  3FQZ A;  4M6K A;  3JWK A;  4ELE A;  2HM9 A;  3JWF A;  3NZB X;  3SA2 A;  3KFY A;  2W9G A;  3K2H A;  1RX3 A;  5HF2 X;  2BLC A;  2FZJ A;  4KNE A;  3QLR A;  1RX5 A;  2C2S A;  5CC9 A;  3SAI A;  1DIS A;  2AZN A;  3HJ3 A;  3FRD X;  4KJJ A;  1DG7 A;  1VJ3 A;  2OBC A;  1RX8 A;  2KGK A;  3QG2 A;  3QLY A;  3ZPG A;  5HQY A;  1HFR A;  3FL8 A;  3EEL A;  3CL9 A;  3SRS X;  3F0U X;  4KY8 A;  2GD9 A;  4G95 A;  3SA1 A;  8DFR A;  1LUD A;  2W3W A;  5HSR A;  4FHB A;  1RX4 A;  2JYB A;  3QYL A;  1MVS A;  3FS6 A;  1DRF A;  1RA3 A;  4TU5 X;  3FL9 A;  1DDR A;  4ELF A;  1DRA A;  5FDA A;  1HFP A;  3IA5 A;  3QLZ A;  3NXO A;  1QZF A;  4FGG A;  4X5H A;  1DR3 A;  2HQP A;  4QLF A;  4PTH A;  3F0B X;  4ELB A;  4ELH A;  3DL5 A;  1DRB A;  2W3A A;  3JVX A;  4KM2 A;  3KY8 A;  3SRW X;  3I8A X;  2HXV A;  1S3Y A;  1JOM A;  5HQZ A;  4P68 A;  3OCH A;  3N0H A;  4P3R A;  4XT8 A;  2LF1 A;  1JUV A;  4ELG A;  1OHK A;  1DHI A;  1SEJ A;  1LY3 A;  4FGH A;  4RGC A;  3KGY A;  1AI9 A;  1J3I A;  3F0S X;  1DAJ A;  5ECX A;  4XT5 A;  5HUI A;  3Q1H A;  1IA3 A;  1RA2 A;  4M7V A;  1TDR A;  2B3Z A;  3L3R A;  4GH8 A;  3FYV X;  2P4G A;  4QJZ D;  2QK8 A;  4M7U A;  1CZ3 A;  1VDR A;  1RA1 A;  4P66 A;  3EEM A;  3GHV A;  4QLE A;  4G3M A;  3SH2 A;  1DR1 A;  4LAE X;  2BLA A;  3SQY X;  2O7P A;  4KYA A;  4KD7 A;  3F91 A;  5E8Q A;  3FYW X;  3D80 A;  4KY4 A;  1D1G A;  1DYR A;  4H97 A;  4M6J A;  4G8Z X;  3QLW A;  1DR7 A;  3JTW A;  4KM0 A;  4NX6 A;  3GHC A;  1U71 A;  2ZZA A;  3KJS A;  3IX9 A;  3OAF A;  1YHO A;  2FZI A;  3D84 X;  2D5N A;  3F8Z A;  3UM5 A;  1OHJ A;  3DL6 A;  3NXR A;  1KLK A;  5EAJ A;  3HBB A;  1LY4 A;  1DYI A;  3JWM A;  4PTJ A;  1U70 A;  2CIG A;  3LG4 A;  5U27 A;  7DFR A;  1CD2 A;  5HPB A;  1J3K A;  3EX8 A;  3DAU A;  4X5I A;  3VCO A;  4QI9 A;  1BZF A;  2XW7 A;  3NZ6 X;  3F0Q X;  3TQA A;  3S3V A;  2W3B A;  3NZD A;  5DXV A;  3S9U A;  4KBN A;  4KEB A;  1PD9 A;  1DHJ A;  2DRC A;  3NXX A;  3IA4 A;  1PDB A;  4IXF X;  2ANO A;  3ZPC A;  2DHF A;  3K47 A;  2H2Q A;  3EEK A;  4PSY A;  4EIZ A;  4HOG A;  3KJR A;  4X5G A;  4XT4 A;  4PDJ A;  3NZC X;  3FRB X;  1RB2 A;  3E0B A;  4DDR A;  1DR6 A;  3I3R A;  3CD2 A;  3FQC A;  2C2T A;  4DFR A;  1DG5 A;  3NU0 A;  3ROA A;  1M78 A;  3CLB A;  3TD8 A;  3IRM A;  3NTZ A;  1DHF A;  3GYF A;  4LAG X;  3TQ9 A;  4NX7 A;  4M2X A;  1RH3 A;  3K45 A;  4M6L A;  1RG7 A;  1DRE A;  3DFR A;  3M09 A;  4KJK A;  4PST A;  3FY8 X;  3TQB A;  1RA9 A;  3NXV A;  1DYJ A;  1RF7 A;  4XEC X; 
#chains in the Genus database with same CATH homology
 5CCC A;  4EJ1 A;  2G6V A;  4I1N A;  3S7A A;  1M79 A;  1DYH A;  4PSS A;  3DGA A;  3F0X X;  3QFX A;  5HT5 A;  1BOZ A;  3JWC A;  5HVB A;  3DAT A;  3RG9 A;  1RC4 A;  3UM8 A;  4QLG A;  2W3M A;  2ITH A;  3FRF X;  4DPD A;  1RX9 A;  1RX1 A;  3FRA X;  1RX6 A;  2ANQ A;  3SR5 X;  3F8Y A;  1JOL A;  3IRO A;  4KL9 A;  4H95 A;  1DIU A;  1E26 A;  3QL3 A;  1M7A A;  1U72 A;  4H96 A;  2CD2 A;  4HOE A;  4IXG X;  4DPH A;  3FRE X;  3QGT A;  1S3U A;  4XRB A;  4X5F A;  3TQ8 A;  1S3V A;  1DLS A;  3QYO A;  4KJL A;  3FQO A;  3RO9 A;  5HF0 X;  4H98 A;  5HI6 A;  4KFJ A;  3SRQ X;  2L28 A;  1RB3 A;  1RX7 A;  2BL9 A;  4HA7 A;  3GHW A;  4Q0E A;  1AOE A;  4KAK A;  4LEK X;  3EEJ A;  4Q67 A;  3JW5 A;  3NZ9 X;  5HT4 A;  4CD2 A;  1IA4 A;  4Q0D A;  4QHV A;  1AO8 A;  3DRC A;  4HA9 A;  4XT6 A;  1J3J A;  3NXT A;  1RA8 A;  1DR2 A;  4P3Q A;  3M08 A;  1DF7 A;  3NXY A;  1DR5 A;  3INV A;  3SRU X;  4QJC A;  3DG8 A;  6DFR A;  1MVT A;  3NRR A;  5ECC A;  2W3V A;  5DFR A;  2W9S A;  4Q6A A;  3SRR X;  1DDS A;  1ZDR A;  3SGY A;  3QL0 A;  4XT7 A;  2W9T A;  3FY9 X;  2D0K A;  4I13 A;  4LAH X;  4ECK A;  4DP3 A;  1KMV A;  2OIP A;  3QLS A;  4KLX A;  4HOF A;  1HFQ A;  1PD8 A;  3FQF A;  5JA3 A;  1IA1 A;  3NZA X;  3R33 A;  1DLR A;  4IXE D;  3FQ0 A;  4XE6 X;  4OR7 A;  3GI2 A;  1DR4 A;  1IA2 A;  5HSU A;  1KMS A;  4X5J A;  3FQV A;  5JG0 X;  3JSU A;  4EIG A;  1S3W A;  3UM6 A;  3CSE A;  1RX2 A;  3IRN A;  1RE7 A;  3JW3 A;  1RD7 A;  1DRH A;  5U26 A;  5HVE A;  3K74 A;  3F0V X;  1DG8 A;  3QLX A;  2BLB A;  2INQ A;  2W9H A;  4EIL A;  3EIG A;  4OSG A;  2FZH A;  3FQZ A;  4M6K A;  3JWK A;  4ELE A;  2HM9 A;  3JWF A;  3NZB X;  3SA2 A;  3KFY A;  2W9G A;  3K2H A;  1RX3 A;  5HF2 X;  2BLC A;  2FZJ A;  4KNE A;  3QLR A;  1RX5 A;  2C2S A;  5CC9 A;  3SAI A;  1DIS A;  2AZN A;  3HJ3 A;  3FRD X;  4KJJ A;  1DG7 A;  1VJ3 A;  2OBC A;  1RX8 A;  2KGK A;  3QG2 A;  3QLY A;  3ZPG A;  5HQY A;  1HFR A;  3FL8 A;  3EEL A;  3CL9 A;  3SRS X;  3F0U X;  4KY8 A;  2GD9 A;  4G95 A;  3SA1 A;  8DFR A;  1LUD A;  2W3W A;  5HSR A;  4FHB A;  1RX4 A;  2JYB A;  3QYL A;  1MVS A;  3FS6 A;  1DRF A;  1RA3 A;  4TU5 X;  3FL9 A;  1DDR A;  4ELF A;  1DRA A;  5FDA A;  1HFP A;  3IA5 A;  3QLZ A;  3NXO A;  1QZF A;  4FGG A;  4X5H A;  1DR3 A;  2HQP A;  4QLF A;  4PTH A;  3F0B X;  4ELB A;  4ELH A;  3DL5 A;  1DRB A;  2W3A A;  3JVX A;  4KM2 A;  3KY8 A;  3SRW X;  3I8A X;  2HXV A;  1S3Y A;  1JOM A;  5HQZ A;  4P68 A;  3OCH A;  3N0H A;  4P3R A;  4XT8 A;  2LF1 A;  1JUV A;  4ELG A;  1OHK A;  1DHI A;  1SEJ A;  1LY3 A;  4FGH A;  4RGC A;  3KGY A;  1AI9 A;  1J3I A;  3F0S X;  1DAJ A;  5ECX A;  4XT5 A;  5HUI A;  3Q1H A;  1IA3 A;  1RA2 A;  4M7V A;  1TDR A;  2B3Z A;  3L3R A;  4GH8 A;  3FYV X;  2P4G A;  4QJZ D;  2QK8 A;  4M7U A;  1CZ3 A;  1VDR A;  1RA1 A;  4P66 A;  3EEM A;  3GHV A;  4QLE A;  4G3M A;  3SH2 A;  1DR1 A;  4LAE X;  2BLA A;  3SQY X;  2O7P A;  4KYA A;  4KD7 A;  3F91 A;  5E8Q A;  3FYW X;  3D80 A;  4KY4 A;  1D1G A;  1DYR A;  4H97 A;  4M6J A;  4G8Z X;  3QLW A;  1DR7 A;  3JTW A;  4KM0 A;  4NX6 A;  3GHC A;  1U71 A;  2ZZA A;  3KJS A;  3IX9 A;  3OAF A;  1YHO A;  2FZI A;  3D84 X;  2D5N A;  3F8Z A;  3UM5 A;  1OHJ A;  3DL6 A;  3NXR A;  1KLK A;  5EAJ A;  3HBB A;  1LY4 A;  1DYI A;  3JWM A;  4PTJ A;  1U70 A;  2CIG A;  3LG4 A;  5U27 A;  7DFR A;  1CD2 A;  5HPB A;  1J3K A;  3EX8 A;  3DAU A;  4X5I A;  3VCO A;  4QI9 A;  1BZF A;  2XW7 A;  3NZ6 X;  3F0Q X;  3TQA A;  3S3V A;  2W3B A;  3NZD A;  5DXV A;  3S9U A;  4KBN A;  4KEB A;  1PD9 A;  1DHJ A;  2DRC A;  3NXX A;  3IA4 A;  1PDB A;  4IXF X;  2ANO A;  3ZPC A;  2DHF A;  3K47 A;  2H2Q A;  3EEK A;  4PSY A;  4EIZ A;  4HOG A;  3KJR A;  4X5G A;  4XT4 A;  4PDJ A;  3NZC X;  3FRB X;  1RB2 A;  3E0B A;  4DDR A;  1DR6 A;  3I3R A;  3CD2 A;  3FQC A;  2C2T A;  4DFR A;  1DG5 A;  3NU0 A;  3ROA A;  1M78 A;  3CLB A;  3TD8 A;  3IRM A;  3NTZ A;  1DHF A;  3GYF A;  4LAG X;  3TQ9 A;  4NX7 A;  4M2X A;  1RH3 A;  3K45 A;  4M6L A;  1RG7 A;  1DRE A;  3DFR A;  3M09 A;  4KJK A;  4PST A;  3FY8 X;  3TQB A;  1RA9 A;  3NXV A;  1DYJ A;  1RF7 A;  4XEC X; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...