1M78A

Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 5-chloryl-2,4,6-quinazolinetriamine (gw1225)
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
192
structure length
192
Chain Sequence
MLKPNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-Ray Crystallographic Studies of Candida Albicans Dihydrofolate Reductase. High Resolution Structures of the Holoenzyme and an Inhibited Ternary Complex.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Candida albicans
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 58
structure length 192
sequence length 192
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2002-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1m78A00
1DYRA 1DRFA 4P66A 3INVA 1DG5A 2G6VA 1M79A 2BLAA 3NZBX 1RC4A 1IA3A 1DISA 4X5HA 3NZDA 3FL9A 3QLRA 4KL9A 4M6KA 5HPBA 1RA3A 3SH2A 2P4GA 5HT4A 4EJ1A 3F91A 3VCOA 3SR5X 4FHBA 3FQCA 3Q1HA 2ITHA 1JOMA 5JA3A 4QI9A 5HQZA 5HT5A 3FS6A 5FDAA 3S7AA 1DR1A 1MVTA 1U72A 2W9HA 1J3JA 3FRBX 3FRDX 4Q0DA 1DRHA 1SEJA 3CL9A 2CD2A 4ELGA 3FRAX 3QLSA 2D0KA 1S3UA 1QZFA 3K2HA 2AZNA 4HOGA 5ECCA 3SQYX 4G3MA 3JVXA 3GHVA 4LAGX 4XT6A 4P3QA 1DYIA 3NZCX 3NZ6X 3SRUX 5HF2X 2L28A 3JTWA 4HA7A 3S9UA 1DHJA 3KY8A 2XW7A 1RH3A 3KJSA 3I8AX 2LF1A 3DAUA 3F0XX 3JWKA 4KYAA 1RB3A 5HVEA 3FL8A 1U71A 1BOZA 2BLBA 3DATA 4QJCA 5EAJA 3F8ZA 3R33A 4G95A 2W3VA 4KJKA 3NXXA 1DDSA 4DPHA 1DAJA 4HOFA 3SGYA 4M7UA 1RA1A 3SRRX 1RX4A 1DLSA 1RF7A 1HFQA 3N0HA 3NU0A 1DR4A 3K74A 4GH8A 4QJZD 3SRWX 3UM8A 5HVBA 4XECX 3TQAA 3QYLA 3TQBA 3F0UX 1TDRA 1DF7A 4X5JA 4QLGA 5CC9A 4KY4A 3NTZA 2BLCA 3IX9A 1KMSA 4I13A 1RG7A 1PDBA 3E0BA 3FYWX 3FQFA 4EILA 3F0BX 3ZPCA 2W9SA 3FQZA 2CIGA 3NXYA 4KY8A 2QK8A 1RX1A 4NX7A 1CD2A 1IA4A 4TU5X 3FY9X 5DXVA 1RA9A 1RX7A 3JW3A 2W3BA 3QL3A 4X5IA 4KLXA 1HFRA 5JG0X 4M2XA 4OSGA 4X5GA 2W9TA 3F0VX 1IA2A 1LUDA 5E8QA 1RD7A 2HXVA 1DR6A 3CD2A 3GHCA 1AI9A 4CD2A 1DG7A 4ELBA 1JUVA 4LAEX 3DRCA 1D1GA 3IROA 4H95A 1DG8A 3D80A 4LAHX 2OIPA 1J3KA 3QLZA 1U70A 3CLBA 3FQVA 4XT7A 2FZJA 3M09A 3FYVX 1KMVA 1DYHA 3QLXA 3NXTA 3OCHA 4Q6AA 5HF0X 1RA8A 4LEKX 4PTJA 3JSUA 2BL9A 1RX2A 3FQ0A 3SAIA 3QLWA 3NRRA 2DRCA 1DHFA 3FRFX 2HQPA 5DFRA 4QLFA 4RGCA 1LY3A 1M78A 4DPDA 1VJ3A 2C2TA 4KEBA 3ZPGA 1MVSA 4Q67A 3TQ8A 4KNEA 2W9GA 1DR7A 4IXGX 4KM2A 4H98A 1RX9A 3SRSX 1RX5A 4QLEA 3EX8A 3GYFA 4ELFA 3SA1A 4DP3A 6DFRA 3DL6A 2GD9A 1CZ3A 1ZDRA 3DL5A 3K45A 3QLYA 4IXFX 2ANQA 1JOLA 3OAFA 3DFRA 3FREX 4I1NA 1M7AA 1DHIA 3QG2A 1DLRA 3JWFA 3KFYA 1DR2A 3JWCA 3NZ9X 1S3VA 3QYOA 3K47A 3QFXA 1AOEA 3SRQX 3JWMA 3EELA 4PSTA 1DR5A 3KGYA 3KJRA 3EEJA 3TD8A 1VDRA 1PD8A 4NX6A 3ROAA 4XT5A 2ZZAA 4KBNA 3S3VA 3EEKA 4XT8A 1DRAA 3SA2A 3NXOA 1DYJA 4M6JA 3UM5A 3RG9A 2DHFA 1RX6A 5HQYA 1RE7A 4XE6X 2W3MA 4X5FA 4HOEA 4Q0EA 1YHOA 4EIGA 2INQA 3EIGA 3JW5A 4ECKA 3DGAA 4H97A 4M6LA 1RX3A 3NXRA 3UM6A 3D84X 3I3RA 3TQ9A 4OR7A 3IA4A 2FZHA 3L3RA 3F8YA 3LG4A 2OBCA 2W3WA 3RO9A 1RX8A 2KGKA 4PDJA 4PTHA 1AO8A 4HA9A 4KAKA 5HI6A 2C2SA 3GHWA 2W3AA 3NZAX 4ELHA 1J3IA 1KLKA 3DG8A 1S3WA 2HM9A 2D5NA 5CCCA 5HUIA 4PSSA 1PD9A 2H2QA 3GI2A 4M7VA 4KFJA 2ANOA 1OHJA 3FY8X 4P3RA 8DFRA 4H96A 5ECXA 4FGGA 3NXVA 4KD7A 5U26A 1OHKA 1E26A 4G8ZX 4DDRA 5HSUA 4KM0A 1DDRA 3EEMA 3M08A 1RB2A 4ELEA 3F0SX 4KJJA 1RA2A 1DREA 3CSEA 4QHVA 1BZFA 3F0QX 3QGTA 2JYBA 7DFRA 4PSYA 2B3ZA 4XT4A 1IA1A 3HJ3A 2FZIA 1S3YA 4P68A 4DFRA 3IRNA 4IXED 1DRBA 1LY4A 3QL0A 3HBBA 3FQOA 1DR3A 4XRBA 5U27A 4FGHA 1DIUA 4KJLA 2O7PA 5HSRA 1HFPA 3IA5A 3IRMA 4EIZA
chains in the Genus database with same CATH superfamily
1DYRA 1DRFA 4P66A 3INVA 1DG5A 2G6VA 1M79A 2BLAA 3NZBX 1RC4A 1IA3A 1DISA 4X5HA 3NZDA 3FL9A 3QLRA 4KL9A 4M6KA 5HPBA 1RA3A 3SH2A 2P4GA 5HT4A 4EJ1A 3F91A 3VCOA 3SR5X 4FHBA 3FQCA 3Q1HA 2ITHA 1JOMA 5JA3A 4QI9A 5HQZA 5HT5A 3FS6A 5FDAA 3S7AA 1DR1A 1MVTA 1U72A 2W9HA 1J3JA 3FRBX 3FRDX 4Q0DA 1DRHA 1SEJA 3CL9A 2CD2A 4ELGA 3FRAX 3QLSA 2D0KA 1S3UA 1QZFA 3K2HA 2AZNA 4HOGA 5ECCA 3SQYX 4G3MA 3JVXA 3GHVA 4LAGX 4XT6A 4P3QA 1DYIA 3NZCX 3NZ6X 3SRUX 5HF2X 2L28A 3JTWA 4HA7A 3S9UA 1DHJA 3KY8A 2XW7A 1RH3A 3KJSA 3I8AX 2LF1A 3DAUA 3F0XX 3JWKA 4KYAA 1RB3A 5HVEA 3FL8A 1U71A 1BOZA 2BLBA 3DATA 4QJCA 5EAJA 3F8ZA 3R33A 4G95A 2W3VA 4KJKA 3NXXA 1DDSA 4DPHA 1DAJA 4HOFA 3SGYA 4M7UA 1RA1A 3SRRX 1RX4A 1DLSA 1RF7A 1HFQA 3N0HA 3NU0A 1DR4A 3K74A 4GH8A 4QJZD 3SRWX 3UM8A 5HVBA 4XECX 3TQAA 3QYLA 3TQBA 3F0UX 1TDRA 1DF7A 4X5JA 4QLGA 5CC9A 4KY4A 3NTZA 2BLCA 3IX9A 1KMSA 4I13A 1RG7A 1PDBA 3E0BA 3FYWX 3FQFA 4EILA 3F0BX 3ZPCA 2W9SA 3FQZA 2CIGA 3NXYA 4KY8A 2QK8A 1RX1A 4NX7A 1CD2A 1IA4A 4TU5X 3FY9X 5DXVA 1RA9A 1RX7A 3JW3A 2W3BA 3QL3A 4X5IA 4KLXA 1HFRA 5JG0X 4M2XA 4OSGA 4X5GA 2W9TA 3F0VX 1IA2A 1LUDA 5E8QA 1RD7A 2HXVA 1DR6A 3CD2A 3GHCA 1AI9A 4CD2A 1DG7A 4ELBA 1JUVA 4LAEX 3DRCA 1D1GA 3IROA 4H95A 1DG8A 3D80A 4LAHX 2OIPA 1J3KA 3QLZA 1U70A 3CLBA 3FQVA 4XT7A 2FZJA 3M09A 3FYVX 1KMVA 1DYHA 3QLXA 3NXTA 3OCHA 4Q6AA 5HF0X 1RA8A 4LEKX 4PTJA 3JSUA 2BL9A 1RX2A 3FQ0A 3SAIA 3QLWA 3NRRA 2DRCA 1DHFA 3FRFX 2HQPA 5DFRA 4QLFA 4RGCA 1LY3A 1M78A 4DPDA 1VJ3A 2C2TA 4KEBA 3ZPGA 1MVSA 4Q67A 3TQ8A 4KNEA 2W9GA 1DR7A 4IXGX 4KM2A 4H98A 1RX9A 3SRSX 1RX5A 4QLEA 3EX8A 3GYFA 4ELFA 3SA1A 4DP3A 6DFRA 3DL6A 2GD9A 1CZ3A 1ZDRA 3DL5A 3K45A 3QLYA 4IXFX 2ANQA 1JOLA 3OAFA 3DFRA 3FREX 4I1NA 1M7AA 1DHIA 3QG2A 1DLRA 3JWFA 3KFYA 1DR2A 3JWCA 3NZ9X 1S3VA 3QYOA 3K47A 3QFXA 1AOEA 3SRQX 3JWMA 3EELA 4PSTA 1DR5A 3KGYA 3KJRA 3EEJA 3TD8A 1VDRA 1PD8A 4NX6A 3ROAA 4XT5A 2ZZAA 4KBNA 3S3VA 3EEKA 4XT8A 1DRAA 3SA2A 3NXOA 1DYJA 4M6JA 3UM5A 3RG9A 2DHFA 1RX6A 5HQYA 1RE7A 4XE6X 2W3MA 4X5FA 4HOEA 4Q0EA 1YHOA 4EIGA 2INQA 3EIGA 3JW5A 4ECKA 3DGAA 4H97A 4M6LA 1RX3A 3NXRA 3UM6A 3D84X 3I3RA 3TQ9A 4OR7A 3IA4A 2FZHA 3L3RA 3F8YA 3LG4A 2OBCA 2W3WA 3RO9A 1RX8A 2KGKA 4PDJA 4PTHA 1AO8A 4HA9A 4KAKA 5HI6A 2C2SA 3GHWA 2W3AA 3NZAX 4ELHA 1J3IA 1KLKA 3DG8A 1S3WA 2HM9A 2D5NA 5CCCA 5HUIA 4PSSA 1PD9A 2H2QA 3GI2A 4M7VA 4KFJA 2ANOA 1OHJA 3FY8X 4P3RA 8DFRA 4H96A 5ECXA 4FGGA 3NXVA 4KD7A 5U26A 1OHKA 1E26A 4G8ZX 4DDRA 5HSUA 4KM0A 1DDRA 3EEMA 3M08A 1RB2A 4ELEA 3F0SX 4KJJA 1RA2A 1DREA 3CSEA 4QHVA 1BZFA 3F0QX 3QGTA 2JYBA 7DFRA 4PSYA 2B3ZA 4XT4A 1IA1A 3HJ3A 2FZIA 1S3YA 4P68A 4DFRA 3IRNA 4IXED 1DRBA 1LY4A 3QL0A 3HBBA 3FQOA 1DR3A 4XRBA 5U27A 4FGHA 1DIUA 4KJLA 2O7PA 5HSRA 1HFPA 3IA5A 3IRMA 4EIZA
chains in the Genus database with same CATH topology
1DYRA 1DRFA 4P66A 3INVA 1DG5A 2G6VA 1M79A 2BLAA 3NZBX 1RC4A 1IA3A 1DISA 4X5HA 3NZDA 3FL9A 3QLRA 4KL9A 4M6KA 5HPBA 1RA3A 3SH2A 2P4GA 5HT4A 4EJ1A 3F91A 3VCOA 3SR5X 4FHBA 3FQCA 3Q1HA 2ITHA 1JOMA 5JA3A 4QI9A 5HQZA 5HT5A 3FS6A 5FDAA 3S7AA 1DR1A 1MVTA 1U72A 2W9HA 1J3JA 3FRBX 3FRDX 4Q0DA 1DRHA 1SEJA 3CL9A 2CD2A 4ELGA 3FRAX 3QLSA 2D0KA 1S3UA 1QZFA 3K2HA 2AZNA 4HOGA 5ECCA 3SQYX 4G3MA 3JVXA 3GHVA 4LAGX 4XT6A 4P3QA 1DYIA 3NZCX 3NZ6X 3SRUX 5HF2X 2L28A 3JTWA 4HA7A 3S9UA 1DHJA 3KY8A 2XW7A 1RH3A 3KJSA 3I8AX 2LF1A 3DAUA 3F0XX 3JWKA 4KYAA 1RB3A 5HVEA 3FL8A 1U71A 1BOZA 2BLBA 3DATA 4QJCA 5EAJA 3F8ZA 3R33A 4G95A 2W3VA 4KJKA 3NXXA 1DDSA 4DPHA 1DAJA 4HOFA 3SGYA 4M7UA 1RA1A 3SRRX 1RX4A 1DLSA 1RF7A 1HFQA 3N0HA 3NU0A 1DR4A 3K74A 4GH8A 4QJZD 3SRWX 3UM8A 5HVBA 4XECX 3TQAA 3QYLA 3TQBA 3F0UX 1TDRA 1DF7A 4X5JA 4QLGA 5CC9A 4KY4A 3NTZA 2BLCA 3IX9A 1KMSA 4I13A 1RG7A 1PDBA 3E0BA 3FYWX 3FQFA 4EILA 3F0BX 3ZPCA 2W9SA 3FQZA 2CIGA 3NXYA 4KY8A 2QK8A 1RX1A 4NX7A 1CD2A 1IA4A 4TU5X 3FY9X 5DXVA 1RA9A 1RX7A 3JW3A 2W3BA 3QL3A 4X5IA 4KLXA 1HFRA 5JG0X 4M2XA 4OSGA 4X5GA 2W9TA 3F0VX 1IA2A 1LUDA 5E8QA 1RD7A 2HXVA 1DR6A 3CD2A 3GHCA 1AI9A 4CD2A 1DG7A 4ELBA 1JUVA 4LAEX 3DRCA 1D1GA 3IROA 4H95A 1DG8A 3D80A 4LAHX 2OIPA 1J3KA 3QLZA 1U70A 3CLBA 3FQVA 4XT7A 2FZJA 3M09A 3FYVX 1KMVA 1DYHA 3QLXA 3NXTA 3OCHA 4Q6AA 5HF0X 1RA8A 4LEKX 4PTJA 3JSUA 2BL9A 1RX2A 3FQ0A 3SAIA 3QLWA 3NRRA 2DRCA 1DHFA 3FRFX 2HQPA 5DFRA 4QLFA 4RGCA 1LY3A 1M78A 4DPDA 1VJ3A 2C2TA 4KEBA 3ZPGA 1MVSA 4Q67A 3TQ8A 4KNEA 2W9GA 1DR7A 4IXGX 4KM2A 4H98A 1RX9A 3SRSX 1RX5A 4QLEA 3EX8A 3GYFA 4ELFA 3SA1A 4DP3A 6DFRA 3DL6A 2GD9A 1CZ3A 1ZDRA 3DL5A 3K45A 3QLYA 4IXFX 2ANQA 1JOLA 3OAFA 3DFRA 3FREX 4I1NA 1M7AA 1DHIA 3QG2A 1DLRA 3JWFA 3KFYA 1DR2A 3JWCA 3NZ9X 1S3VA 3QYOA 3K47A 3QFXA 1AOEA 3SRQX 3JWMA 3EELA 4PSTA 1DR5A 3KGYA 3KJRA 3EEJA 3TD8A 1VDRA 1PD8A 4NX6A 3ROAA 4XT5A 2ZZAA 4KBNA 3S3VA 3EEKA 4XT8A 1DRAA 3SA2A 3NXOA 1DYJA 4M6JA 3UM5A 3RG9A 2DHFA 1RX6A 5HQYA 1RE7A 4XE6X 2W3MA 4X5FA 4HOEA 4Q0EA 1YHOA 4EIGA 2INQA 3EIGA 3JW5A 4ECKA 3DGAA 4H97A 4M6LA 1RX3A 3NXRA 3UM6A 3D84X 3I3RA 3TQ9A 4OR7A 3IA4A 2FZHA 3L3RA 3F8YA 3LG4A 2OBCA 2W3WA 3RO9A 1RX8A 2KGKA 4PDJA 4PTHA 1AO8A 4HA9A 4KAKA 5HI6A 2C2SA 3GHWA 2W3AA 3NZAX 4ELHA 1J3IA 1KLKA 3DG8A 1S3WA 2HM9A 2D5NA 5CCCA 5HUIA 4PSSA 1PD9A 2H2QA 3GI2A 4M7VA 4KFJA 2ANOA 1OHJA 3FY8X 4P3RA 8DFRA 4H96A 5ECXA 4FGGA 3NXVA 4KD7A 5U26A 1OHKA 1E26A 4G8ZX 4DDRA 5HSUA 4KM0A 1DDRA 3EEMA 3M08A 1RB2A 4ELEA 3F0SX 4KJJA 1RA2A 1DREA 3CSEA 4QHVA 1BZFA 3F0QX 3QGTA 2JYBA 7DFRA 4PSYA 2B3ZA 4XT4A 1IA1A 3HJ3A 2FZIA 1S3YA 4P68A 4DFRA 3IRNA 4IXED 1DRBA 1LY4A 3QL0A 3HBBA 3FQOA 1DR3A 4XRBA 5U27A 4FGHA 1DIUA 4KJLA 2O7PA 5HSRA 1HFPA 3IA5A 3IRMA 4EIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DYR A;  1DRF A;  4P66 A;  3INV A;  1DG5 A;  2G6V A;  1M79 A;  2BLA A;  3NZB X;  1RC4 A;  1IA3 A;  1DIS A;  4X5H A;  3NZD A;  3FL9 A;  3QLR A;  4KL9 A;  4M6K A;  5HPB A;  1RA3 A;  3SH2 A;  2P4G A;  5HT4 A;  4EJ1 A;  3F91 A;  3VCO A;  3SR5 X;  4FHB A;  3FQC A;  3Q1H A;  2ITH A;  1JOM A;  5JA3 A;  4QI9 A;  5HQZ A;  5HT5 A;  3FS6 A;  5FDA A;  3S7A A;  1DR1 A;  1MVT A;  1U72 A;  2W9H A;  1J3J A;  3FRB X;  3FRD X;  4Q0D A;  1DRH A;  1SEJ A;  3CL9 A;  2CD2 A;  4ELG A;  3FRA X;  3QLS A;  2D0K A;  1S3U A;  1QZF A;  3K2H A;  2AZN A;  4HOG A;  5ECC A;  3SQY X;  4G3M A;  3JVX A;  3GHV A;  4LAG X;  4XT6 A;  4P3Q A;  1DYI A;  3NZC X;  3NZ6 X;  3SRU X;  5HF2 X;  2L28 A;  3JTW A;  4HA7 A;  3S9U A;  1DHJ A;  3KY8 A;  2XW7 A;  1RH3 A;  3KJS A;  3I8A X;  2LF1 A;  3DAU A;  3F0X X;  3JWK A;  4KYA A;  1RB3 A;  5HVE A;  3FL8 A;  1U71 A;  1BOZ A;  2BLB A;  3DAT A;  4QJC A;  5EAJ A;  3F8Z A;  3R33 A;  4G95 A;  2W3V A;  4KJK A;  3NXX A;  1DDS A;  4DPH A;  1DAJ A;  4HOF A;  3SGY A;  4M7U A;  1RA1 A;  3SRR X;  1RX4 A;  1DLS A;  1RF7 A;  1HFQ A;  3N0H A;  3NU0 A;  1DR4 A;  3K74 A;  4GH8 A;  4QJZ D;  3SRW X;  3UM8 A;  5HVB A;  4XEC X;  3TQA A;  3QYL A;  3TQB A;  3F0U X;  1TDR A;  1DF7 A;  4X5J A;  4QLG A;  5CC9 A;  4KY4 A;  3NTZ A;  2BLC A;  3IX9 A;  1KMS A;  4I13 A;  1RG7 A;  1PDB A;  3E0B A;  3FYW X;  3FQF A;  4EIL A;  3F0B X;  3ZPC A;  2W9S A;  3FQZ A;  2CIG A;  3NXY A;  4KY8 A;  2QK8 A;  1RX1 A;  4NX7 A;  1CD2 A;  1IA4 A;  4TU5 X;  3FY9 X;  5DXV A;  1RA9 A;  1RX7 A;  3JW3 A;  2W3B A;  3QL3 A;  4X5I A;  4KLX A;  1HFR A;  5JG0 X;  4M2X A;  4OSG A;  4X5G A;  2W9T A;  3F0V X;  1IA2 A;  1LUD A;  5E8Q A;  1RD7 A;  2HXV A;  1DR6 A;  3CD2 A;  3GHC A;  1AI9 A;  4CD2 A;  1DG7 A;  4ELB A;  1JUV A;  4LAE X;  3DRC A;  1D1G A;  3IRO A;  4H95 A;  1DG8 A;  3D80 A;  4LAH X;  2OIP A;  1J3K A;  3QLZ A;  1U70 A;  3CLB A;  3FQV A;  4XT7 A;  2FZJ A;  3M09 A;  3FYV X;  1KMV A;  1DYH A;  3QLX A;  3NXT A;  3OCH A;  4Q6A A;  5HF0 X;  1RA8 A;  4LEK X;  4PTJ A;  3JSU A;  2BL9 A;  1RX2 A;  3FQ0 A;  3SAI A;  3QLW A;  3NRR A;  2DRC A;  1DHF A;  3FRF X;  2HQP A;  5DFR A;  4QLF A;  4RGC A;  1LY3 A;  1M78 A;  4DPD A;  1VJ3 A;  2C2T A;  4KEB A;  3ZPG A;  1MVS A;  4Q67 A;  3TQ8 A;  4KNE A;  2W9G A;  1DR7 A;  4IXG X;  4KM2 A;  4H98 A;  1RX9 A;  3SRS X;  1RX5 A;  4QLE A;  3EX8 A;  3GYF A;  4ELF A;  3SA1 A;  4DP3 A;  6DFR A;  3DL6 A;  2GD9 A;  1CZ3 A;  1ZDR A;  3DL5 A;  3K45 A;  3QLY A;  4IXF X;  2ANQ A;  1JOL A;  3OAF A;  3DFR A;  3FRE X;  4I1N A;  1M7A A;  1DHI A;  3QG2 A;  1DLR A;  3JWF A;  3KFY A;  1DR2 A;  3JWC A;  3NZ9 X;  1S3V A;  3QYO A;  3K47 A;  3QFX A;  1AOE A;  3SRQ X;  3JWM A;  3EEL A;  4PST A;  1DR5 A;  3KGY A;  3KJR A;  3EEJ A;  3TD8 A;  1VDR A;  1PD8 A;  4NX6 A;  3ROA A;  4XT5 A;  2ZZA A;  4KBN A;  3S3V A;  3EEK A;  4XT8 A;  1DRA A;  3SA2 A;  3NXO A;  1DYJ A;  4M6J A;  3UM5 A;  3RG9 A;  2DHF A;  1RX6 A;  5HQY A;  1RE7 A;  4XE6 X;  2W3M A;  4X5F A;  4HOE A;  4Q0E A;  1YHO A;  4EIG A;  2INQ A;  3EIG A;  3JW5 A;  4ECK A;  3DGA A;  4H97 A;  4M6L A;  1RX3 A;  3NXR A;  3UM6 A;  3D84 X;  3I3R A;  3TQ9 A;  4OR7 A;  3IA4 A;  2FZH A;  3L3R A;  3F8Y A;  3LG4 A;  2OBC A;  2W3W A;  3RO9 A;  1RX8 A;  2KGK A;  4PDJ A;  4PTH A;  1AO8 A;  4HA9 A;  4KAK A;  5HI6 A;  2C2S A;  3GHW A;  2W3A A;  3NZA X;  4ELH A;  1J3I A;  1KLK A;  3DG8 A;  1S3W A;  2HM9 A;  2D5N A;  5CCC A;  5HUI A;  4PSS A;  1PD9 A;  2H2Q A;  3GI2 A;  4M7V A;  4KFJ A;  2ANO A;  1OHJ A;  3FY8 X;  4P3R A;  8DFR A;  4H96 A;  5ECX A;  4FGG A;  3NXV A;  4KD7 A;  5U26 A;  1OHK A;  1E26 A;  4G8Z X;  4DDR A;  5HSU A;  4KM0 A;  1DDR A;  3EEM A;  3M08 A;  1RB2 A;  4ELE A;  3F0S X;  4KJJ A;  1RA2 A;  1DRE A;  3CSE A;  4QHV A;  1BZF A;  3F0Q X;  3QGT A;  2JYB A;  7DFR A;  4PSY A;  2B3Z A;  4XT4 A;  1IA1 A;  3HJ3 A;  2FZI A;  1S3Y A;  4P68 A;  4DFR A;  3IRN A;  4IXE D;  1DRB A;  1LY4 A;  3QL0 A;  3HBB A;  3FQO A;  1DR3 A;  4XRB A;  5U27 A;  4FGH A;  1DIU A;  4KJL A;  2O7P A;  5HSR A;  1HFP A;  3IA5 A;  3IRM A;  4EIZ A; 
#chains in the Genus database with same CATH topology
 1DYR A;  1DRF A;  4P66 A;  3INV A;  1DG5 A;  2G6V A;  1M79 A;  2BLA A;  3NZB X;  1RC4 A;  1IA3 A;  1DIS A;  4X5H A;  3NZD A;  3FL9 A;  3QLR A;  4KL9 A;  4M6K A;  5HPB A;  1RA3 A;  3SH2 A;  2P4G A;  5HT4 A;  4EJ1 A;  3F91 A;  3VCO A;  3SR5 X;  4FHB A;  3FQC A;  3Q1H A;  2ITH A;  1JOM A;  5JA3 A;  4QI9 A;  5HQZ A;  5HT5 A;  3FS6 A;  5FDA A;  3S7A A;  1DR1 A;  1MVT A;  1U72 A;  2W9H A;  1J3J A;  3FRB X;  3FRD X;  4Q0D A;  1DRH A;  1SEJ A;  3CL9 A;  2CD2 A;  4ELG A;  3FRA X;  3QLS A;  2D0K A;  1S3U A;  1QZF A;  3K2H A;  2AZN A;  4HOG A;  5ECC A;  3SQY X;  4G3M A;  3JVX A;  3GHV A;  4LAG X;  4XT6 A;  4P3Q A;  1DYI A;  3NZC X;  3NZ6 X;  3SRU X;  5HF2 X;  2L28 A;  3JTW A;  4HA7 A;  3S9U A;  1DHJ A;  3KY8 A;  2XW7 A;  1RH3 A;  3KJS A;  3I8A X;  2LF1 A;  3DAU A;  3F0X X;  3JWK A;  4KYA A;  1RB3 A;  5HVE A;  3FL8 A;  1U71 A;  1BOZ A;  2BLB A;  3DAT A;  4QJC A;  5EAJ A;  3F8Z A;  3R33 A;  4G95 A;  2W3V A;  4KJK A;  3NXX A;  1DDS A;  4DPH A;  1DAJ A;  4HOF A;  3SGY A;  4M7U A;  1RA1 A;  3SRR X;  1RX4 A;  1DLS A;  1RF7 A;  1HFQ A;  3N0H A;  3NU0 A;  1DR4 A;  3K74 A;  4GH8 A;  4QJZ D;  3SRW X;  3UM8 A;  5HVB A;  4XEC X;  3TQA A;  3QYL A;  3TQB A;  3F0U X;  1TDR A;  1DF7 A;  4X5J A;  4QLG A;  5CC9 A;  4KY4 A;  3NTZ A;  2BLC A;  3IX9 A;  1KMS A;  4I13 A;  1RG7 A;  1PDB A;  3E0B A;  3FYW X;  3FQF A;  4EIL A;  3F0B X;  3ZPC A;  2W9S A;  3FQZ A;  2CIG A;  3NXY A;  4KY8 A;  2QK8 A;  1RX1 A;  4NX7 A;  1CD2 A;  1IA4 A;  4TU5 X;  3FY9 X;  5DXV A;  1RA9 A;  1RX7 A;  3JW3 A;  2W3B A;  3QL3 A;  4X5I A;  4KLX A;  1HFR A;  5JG0 X;  4M2X A;  4OSG A;  4X5G A;  2W9T A;  3F0V X;  1IA2 A;  1LUD A;  5E8Q A;  1RD7 A;  2HXV A;  1DR6 A;  3CD2 A;  3GHC A;  1AI9 A;  4CD2 A;  1DG7 A;  4ELB A;  1JUV A;  4LAE X;  3DRC A;  1D1G A;  3IRO A;  4H95 A;  1DG8 A;  3D80 A;  4LAH X;  2OIP A;  1J3K A;  3QLZ A;  1U70 A;  3CLB A;  3FQV A;  4XT7 A;  2FZJ A;  3M09 A;  3FYV X;  1KMV A;  1DYH A;  3QLX A;  3NXT A;  3OCH A;  4Q6A A;  5HF0 X;  1RA8 A;  4LEK X;  4PTJ A;  3JSU A;  2BL9 A;  1RX2 A;  3FQ0 A;  3SAI A;  3QLW A;  3NRR A;  2DRC A;  1DHF A;  3FRF X;  2HQP A;  5DFR A;  4QLF A;  4RGC A;  1LY3 A;  1M78 A;  4DPD A;  1VJ3 A;  2C2T A;  4KEB A;  3ZPG A;  1MVS A;  4Q67 A;  3TQ8 A;  4KNE A;  2W9G A;  1DR7 A;  4IXG X;  4KM2 A;  4H98 A;  1RX9 A;  3SRS X;  1RX5 A;  4QLE A;  3EX8 A;  3GYF A;  4ELF A;  3SA1 A;  4DP3 A;  6DFR A;  3DL6 A;  2GD9 A;  1CZ3 A;  1ZDR A;  3DL5 A;  3K45 A;  3QLY A;  4IXF X;  2ANQ A;  1JOL A;  3OAF A;  3DFR A;  3FRE X;  4I1N A;  1M7A A;  1DHI A;  3QG2 A;  1DLR A;  3JWF A;  3KFY A;  1DR2 A;  3JWC A;  3NZ9 X;  1S3V A;  3QYO A;  3K47 A;  3QFX A;  1AOE A;  3SRQ X;  3JWM A;  3EEL A;  4PST A;  1DR5 A;  3KGY A;  3KJR A;  3EEJ A;  3TD8 A;  1VDR A;  1PD8 A;  4NX6 A;  3ROA A;  4XT5 A;  2ZZA A;  4KBN A;  3S3V A;  3EEK A;  4XT8 A;  1DRA A;  3SA2 A;  3NXO A;  1DYJ A;  4M6J A;  3UM5 A;  3RG9 A;  2DHF A;  1RX6 A;  5HQY A;  1RE7 A;  4XE6 X;  2W3M A;  4X5F A;  4HOE A;  4Q0E A;  1YHO A;  4EIG A;  2INQ A;  3EIG A;  3JW5 A;  4ECK A;  3DGA A;  4H97 A;  4M6L A;  1RX3 A;  3NXR A;  3UM6 A;  3D84 X;  3I3R A;  3TQ9 A;  4OR7 A;  3IA4 A;  2FZH A;  3L3R A;  3F8Y A;  3LG4 A;  2OBC A;  2W3W A;  3RO9 A;  1RX8 A;  2KGK A;  4PDJ A;  4PTH A;  1AO8 A;  4HA9 A;  4KAK A;  5HI6 A;  2C2S A;  3GHW A;  2W3A A;  3NZA X;  4ELH A;  1J3I A;  1KLK A;  3DG8 A;  1S3W A;  2HM9 A;  2D5N A;  5CCC A;  5HUI A;  4PSS A;  1PD9 A;  2H2Q A;  3GI2 A;  4M7V A;  4KFJ A;  2ANO A;  1OHJ A;  3FY8 X;  4P3R A;  8DFR A;  4H96 A;  5ECX A;  4FGG A;  3NXV A;  4KD7 A;  5U26 A;  1OHK A;  1E26 A;  4G8Z X;  4DDR A;  5HSU A;  4KM0 A;  1DDR A;  3EEM A;  3M08 A;  1RB2 A;  4ELE A;  3F0S X;  4KJJ A;  1RA2 A;  1DRE A;  3CSE A;  4QHV A;  1BZF A;  3F0Q X;  3QGT A;  2JYB A;  7DFR A;  4PSY A;  2B3Z A;  4XT4 A;  1IA1 A;  3HJ3 A;  2FZI A;  1S3Y A;  4P68 A;  4DFR A;  3IRN A;  4IXE D;  1DRB A;  1LY4 A;  3QL0 A;  3HBB A;  3FQO A;  1DR3 A;  4XRB A;  5U27 A;  4FGH A;  1DIU A;  4KJL A;  2O7P A;  5HSR A;  1HFP A;  3IA5 A;  3IRM A;  4EIZ A; 
#chains in the Genus database with same CATH homology
 1DYR A;  1DRF A;  4P66 A;  3INV A;  1DG5 A;  2G6V A;  1M79 A;  2BLA A;  3NZB X;  1RC4 A;  1IA3 A;  1DIS A;  4X5H A;  3NZD A;  3FL9 A;  3QLR A;  4KL9 A;  4M6K A;  5HPB A;  1RA3 A;  3SH2 A;  2P4G A;  5HT4 A;  4EJ1 A;  3F91 A;  3VCO A;  3SR5 X;  4FHB A;  3FQC A;  3Q1H A;  2ITH A;  1JOM A;  5JA3 A;  4QI9 A;  5HQZ A;  5HT5 A;  3FS6 A;  5FDA A;  3S7A A;  1DR1 A;  1MVT A;  1U72 A;  2W9H A;  1J3J A;  3FRB X;  3FRD X;  4Q0D A;  1DRH A;  1SEJ A;  3CL9 A;  2CD2 A;  4ELG A;  3FRA X;  3QLS A;  2D0K A;  1S3U A;  1QZF A;  3K2H A;  2AZN A;  4HOG A;  5ECC A;  3SQY X;  4G3M A;  3JVX A;  3GHV A;  4LAG X;  4XT6 A;  4P3Q A;  1DYI A;  3NZC X;  3NZ6 X;  3SRU X;  5HF2 X;  2L28 A;  3JTW A;  4HA7 A;  3S9U A;  1DHJ A;  3KY8 A;  2XW7 A;  1RH3 A;  3KJS A;  3I8A X;  2LF1 A;  3DAU A;  3F0X X;  3JWK A;  4KYA A;  1RB3 A;  5HVE A;  3FL8 A;  1U71 A;  1BOZ A;  2BLB A;  3DAT A;  4QJC A;  5EAJ A;  3F8Z A;  3R33 A;  4G95 A;  2W3V A;  4KJK A;  3NXX A;  1DDS A;  4DPH A;  1DAJ A;  4HOF A;  3SGY A;  4M7U A;  1RA1 A;  3SRR X;  1RX4 A;  1DLS A;  1RF7 A;  1HFQ A;  3N0H A;  3NU0 A;  1DR4 A;  3K74 A;  4GH8 A;  4QJZ D;  3SRW X;  3UM8 A;  5HVB A;  4XEC X;  3TQA A;  3QYL A;  3TQB A;  3F0U X;  1TDR A;  1DF7 A;  4X5J A;  4QLG A;  5CC9 A;  4KY4 A;  3NTZ A;  2BLC A;  3IX9 A;  1KMS A;  4I13 A;  1RG7 A;  1PDB A;  3E0B A;  3FYW X;  3FQF A;  4EIL A;  3F0B X;  3ZPC A;  2W9S A;  3FQZ A;  2CIG A;  3NXY A;  4KY8 A;  2QK8 A;  1RX1 A;  4NX7 A;  1CD2 A;  1IA4 A;  4TU5 X;  3FY9 X;  5DXV A;  1RA9 A;  1RX7 A;  3JW3 A;  2W3B A;  3QL3 A;  4X5I A;  4KLX A;  1HFR A;  5JG0 X;  4M2X A;  4OSG A;  4X5G A;  2W9T A;  3F0V X;  1IA2 A;  1LUD A;  5E8Q A;  1RD7 A;  2HXV A;  1DR6 A;  3CD2 A;  3GHC A;  1AI9 A;  4CD2 A;  1DG7 A;  4ELB A;  1JUV A;  4LAE X;  3DRC A;  1D1G A;  3IRO A;  4H95 A;  1DG8 A;  3D80 A;  4LAH X;  2OIP A;  1J3K A;  3QLZ A;  1U70 A;  3CLB A;  3FQV A;  4XT7 A;  2FZJ A;  3M09 A;  3FYV X;  1KMV A;  1DYH A;  3QLX A;  3NXT A;  3OCH A;  4Q6A A;  5HF0 X;  1RA8 A;  4LEK X;  4PTJ A;  3JSU A;  2BL9 A;  1RX2 A;  3FQ0 A;  3SAI A;  3QLW A;  3NRR A;  2DRC A;  1DHF A;  3FRF X;  2HQP A;  5DFR A;  4QLF A;  4RGC A;  1LY3 A;  1M78 A;  4DPD A;  1VJ3 A;  2C2T A;  4KEB A;  3ZPG A;  1MVS A;  4Q67 A;  3TQ8 A;  4KNE A;  2W9G A;  1DR7 A;  4IXG X;  4KM2 A;  4H98 A;  1RX9 A;  3SRS X;  1RX5 A;  4QLE A;  3EX8 A;  3GYF A;  4ELF A;  3SA1 A;  4DP3 A;  6DFR A;  3DL6 A;  2GD9 A;  1CZ3 A;  1ZDR A;  3DL5 A;  3K45 A;  3QLY A;  4IXF X;  2ANQ A;  1JOL A;  3OAF A;  3DFR A;  3FRE X;  4I1N A;  1M7A A;  1DHI A;  3QG2 A;  1DLR A;  3JWF A;  3KFY A;  1DR2 A;  3JWC A;  3NZ9 X;  1S3V A;  3QYO A;  3K47 A;  3QFX A;  1AOE A;  3SRQ X;  3JWM A;  3EEL A;  4PST A;  1DR5 A;  3KGY A;  3KJR A;  3EEJ A;  3TD8 A;  1VDR A;  1PD8 A;  4NX6 A;  3ROA A;  4XT5 A;  2ZZA A;  4KBN A;  3S3V A;  3EEK A;  4XT8 A;  1DRA A;  3SA2 A;  3NXO A;  1DYJ A;  4M6J A;  3UM5 A;  3RG9 A;  2DHF A;  1RX6 A;  5HQY A;  1RE7 A;  4XE6 X;  2W3M A;  4X5F A;  4HOE A;  4Q0E A;  1YHO A;  4EIG A;  2INQ A;  3EIG A;  3JW5 A;  4ECK A;  3DGA A;  4H97 A;  4M6L A;  1RX3 A;  3NXR A;  3UM6 A;  3D84 X;  3I3R A;  3TQ9 A;  4OR7 A;  3IA4 A;  2FZH A;  3L3R A;  3F8Y A;  3LG4 A;  2OBC A;  2W3W A;  3RO9 A;  1RX8 A;  2KGK A;  4PDJ A;  4PTH A;  1AO8 A;  4HA9 A;  4KAK A;  5HI6 A;  2C2S A;  3GHW A;  2W3A A;  3NZA X;  4ELH A;  1J3I A;  1KLK A;  3DG8 A;  1S3W A;  2HM9 A;  2D5N A;  5CCC A;  5HUI A;  4PSS A;  1PD9 A;  2H2Q A;  3GI2 A;  4M7V A;  4KFJ A;  2ANO A;  1OHJ A;  3FY8 X;  4P3R A;  8DFR A;  4H96 A;  5ECX A;  4FGG A;  3NXV A;  4KD7 A;  5U26 A;  1OHK A;  1E26 A;  4G8Z X;  4DDR A;  5HSU A;  4KM0 A;  1DDR A;  3EEM A;  3M08 A;  1RB2 A;  4ELE A;  3F0S X;  4KJJ A;  1RA2 A;  1DRE A;  3CSE A;  4QHV A;  1BZF A;  3F0Q X;  3QGT A;  2JYB A;  7DFR A;  4PSY A;  2B3Z A;  4XT4 A;  1IA1 A;  3HJ3 A;  2FZI A;  1S3Y A;  4P68 A;  4DFR A;  3IRN A;  4IXE D;  1DRB A;  1LY4 A;  3QL0 A;  3HBB A;  3FQO A;  1DR3 A;  4XRB A;  5U27 A;  4FGH A;  1DIU A;  4KJL A;  2O7P A;  5HSR A;  1HFP A;  3IA5 A;  3IRM A;  4EIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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