1RA1A

Dihydrofolate reductase complexed with nicotinamide adenine dinucleotide phosphate (reduced form)
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 42
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1ra1A00
2W3AA 5U27A 3K74A 3FQVA 5HSRA 1LY3A 2DRCA 3DATA 2ANQA 4P3QA 3IROA 4QLEA 4X5JA 3SRQX 4ELHA 3NZDA 1DREA 4Q0DA 1LUDA 3D84X 1DR3A 2BLCA 2D5NA 2H2QA 2ITHA 3EEKA 1RX8A 4ELEA 2FZJA 3NZ6X 4RGCA 1DR7A 1DR2A 2W9TA 4DPDA 1RB2A 2GD9A 3NRRA 1PD8A 1CZ3A 1M79A 3EEMA 3FL8A 3FQZA 4M6KA 3JWCA 4I1NA 4DPHA 4H97A 1J3JA 2OIPA 4FGHA 2W3WA 3INVA 3NXVA 2G6VA 1RX5A 1AOEA 3OCHA 4PSSA 4CD2A 3JWFA 1IA3A 3SQYX 2O7PA 4EILA 1RA1A 2ANOA 3F0XX 3IRMA 3JW3A 4XT8A 3KY8A 5HQZA 3KJRA 3QLWA 5HT4A 2W9SA 2P4GA 1SEJA 5HVBA 4X5HA 2D0KA 3M09A 3IA4A 1RA3A 1J3IA 1DHJA 3IX9A 1AO8A 4QJCA 3FYWX 4M6LA 4KJKA 4IXGX 4H95A 3TQ8A 2XW7A 3L3RA 4KLXA 3FY8X 1RX3A 1DHFA 3E0BA 4G3MA 3F0UX 4HOFA 4M7UA 2C2SA 1S3YA 4QLFA 3JSUA 4HA9A 4XE6X 3DRCA 3SR5X 4LAEX 1RX6A 1LY4A 1OHJA 2AZNA 3UM6A 1D1GA 3FQOA 3QL0A 4XT4A 3N0HA 5HQYA 4OR7A 3QLSA 4DFRA 1DIUA 5JA3A 4KD7A 3KJSA 3KFYA 2HM9A 1BOZA 3GHWA 2L28A 3NXTA 1RD7A 3QLRA 1RH3A 3DGAA 5HPBA 1U72A 2FZIA 4X5GA 2CIGA 1DLSA 3FQ0A 4LAGX 3I3RA 5U26A 4KEBA 3KGYA 3RG9A 4KFJA 4PTHA 3NTZA 4KY8A 1U70A 5HF0X 3IA5A 3OAFA 3FREX 4PSTA 5ECXA 3QYOA 3NXXA 3DL5A 4Q0EA 4DP3A 3CL9A 8DFRA 1DAJA 1IA4A 4M6JA 3NZBX 1DYJA 3NZCX 4Q6AA 1PDBA 3FS6A 4LAHX 1DRHA 4DDRA 1DHIA 1RX2A 4X5FA 3RO9A 1AI9A 1HFPA 1RE7A 3DAUA 3JTWA 4KBNA 1DDSA 3ZPCA 2OBCA 4QI9A 3SRRX 1DG8A 1S3UA 3S3VA 4KY4A 4I13A 3QG2A 4P68A 3NXRA 3EEJA 3I8AX 4KYAA 3TQAA 1HFQA 3SRWX 1DR4A 3JWMA 1DYRA 4H98A 1RA9A 4TU5X 5CCCA 3SA1A 4XRBA 4ELGA 3DL6A 5HF2X 3ROAA 3JVXA 3K45A 2BLBA 2JYBA 1KMVA 3FRBX 3FL9A 4IXED 1DG7A 3S7AA 5HVEA 1QZFA 3NZAX 1RB3A 3R33A 1RG7A 3SGYA 4ECKA 3DFRA 4X5IA 4NX6A 1M78A 4HOEA 4FHBA 4KJJA 3K2HA 4ELBA 1DR6A 3F0QX 2INQA 4PSYA 5EAJA 4PDJA 3SRUX 1CD2A 1DDRA 3TQBA 3GHVA 6DFRA 2HQPA 1JUVA 1RX1A 3D80A 4H96A 4NX7A 2CD2A 2HXVA 3FRFX 3TQ9A 2QK8A 3F8ZA 4LEKX 3FRAX 1RX4A 1DF7A 3Q1HA 1MVTA 1RA2A 1TDRA 5JG0X 1RF7A 4M7VA 4ELFA 3FQCA 3JW5A 1DYIA 3QL3A 4KM2A 3EELA 3TD8A 3VCOA 1BZFA 3SAIA 1S3VA 3NU0A 2FZHA 5DXVA 3K47A 1DLRA 2W3BA 1VJ3A 1OHKA 3FRDX 2LF1A 1JOLA 3QYLA 4G95A 3HBBA 3FYVX 5ECCA 4FGGA 3GYFA 5HUIA 3SH2A 1DR1A 1U71A 4P66A 5HI6A 5DFRA 5HSUA 3SA2A 1IA2A 3F91A 2KGKA 1DR5A 3EIGA 7DFRA 1JOMA 4HOGA 4Q67A 1HFRA 1VDRA 4XECX 3F8YA 1M7AA 4KNEA 3EX8A 3FY9X 4QJZD 2W9HA 2W3MA 3DG8A 1DISA 1DYHA 5HT5A 4EIZA 3UM8A 4EIGA 3F0VX 2BL9A 4QHVA 4EJ1A 1RC4A 1PD9A 2W9GA 4GH8A 4IXFX 3F0BX 3GI2A 1RX9A 1ZDRA 4KJLA 4KL9A 1RX7A 1YHOA 3F0SX 5FDAA 2B3ZA 3QGTA 1DRBA 4M2XA 2BLAA 3JWKA 1DRFA 4QLGA 1S3WA 1KLKA 3CLBA 3QLYA 4P3RA 3FQFA 4HA7A 3GHCA 4OSGA 5E8QA 1E26A 3QLZA 4KM0A 4KAKA 3CSEA 4G8ZX 1IA1A 3QLXA 3UM5A 3NXYA 4PTJA 4XT7A 3IRNA 3QFXA 1DG5A 4XT6A 1RA8A 5CC9A 3SRSX 3LG4A 3ZPGA 3NXOA 3CD2A 1DRAA 1J3KA 2ZZAA 3S9UA 3M08A 1MVSA 3HJ3A 4XT5A 2W3VA 1KMSA 3NZ9X 2DHFA 2C2TA
chains in the Genus database with same CATH superfamily
2W3AA 5U27A 3K74A 3FQVA 5HSRA 1LY3A 2DRCA 3DATA 2ANQA 4P3QA 3IROA 4QLEA 4X5JA 3SRQX 4ELHA 3NZDA 1DREA 4Q0DA 1LUDA 3D84X 1DR3A 2BLCA 2D5NA 2H2QA 2ITHA 3EEKA 1RX8A 4ELEA 2FZJA 3NZ6X 4RGCA 1DR7A 1DR2A 2W9TA 4DPDA 1RB2A 2GD9A 3NRRA 1PD8A 1CZ3A 1M79A 3EEMA 3FL8A 3FQZA 4M6KA 3JWCA 4I1NA 4DPHA 4H97A 1J3JA 2OIPA 4FGHA 2W3WA 3INVA 3NXVA 2G6VA 1RX5A 1AOEA 3OCHA 4PSSA 4CD2A 3JWFA 1IA3A 3SQYX 2O7PA 4EILA 1RA1A 2ANOA 3F0XX 3IRMA 3JW3A 4XT8A 3KY8A 5HQZA 3KJRA 3QLWA 5HT4A 2W9SA 2P4GA 1SEJA 5HVBA 4X5HA 2D0KA 3M09A 3IA4A 1RA3A 1J3IA 1DHJA 3IX9A 1AO8A 4QJCA 3FYWX 4M6LA 4KJKA 4IXGX 4H95A 3TQ8A 2XW7A 3L3RA 4KLXA 3FY8X 1RX3A 1DHFA 3E0BA 4G3MA 3F0UX 4HOFA 4M7UA 2C2SA 1S3YA 4QLFA 3JSUA 4HA9A 4XE6X 3DRCA 3SR5X 4LAEX 1RX6A 1LY4A 1OHJA 2AZNA 3UM6A 1D1GA 3FQOA 3QL0A 4XT4A 3N0HA 5HQYA 4OR7A 3QLSA 4DFRA 1DIUA 5JA3A 4KD7A 3KJSA 3KFYA 2HM9A 1BOZA 3GHWA 2L28A 3NXTA 1RD7A 3QLRA 1RH3A 3DGAA 5HPBA 1U72A 2FZIA 4X5GA 2CIGA 1DLSA 3FQ0A 4LAGX 3I3RA 5U26A 4KEBA 3KGYA 3RG9A 4KFJA 4PTHA 3NTZA 4KY8A 1U70A 5HF0X 3IA5A 3OAFA 3FREX 4PSTA 5ECXA 3QYOA 3NXXA 3DL5A 4Q0EA 4DP3A 3CL9A 8DFRA 1DAJA 1IA4A 4M6JA 3NZBX 1DYJA 3NZCX 4Q6AA 1PDBA 3FS6A 4LAHX 1DRHA 4DDRA 1DHIA 1RX2A 4X5FA 3RO9A 1AI9A 1HFPA 1RE7A 3DAUA 3JTWA 4KBNA 1DDSA 3ZPCA 2OBCA 4QI9A 3SRRX 1DG8A 1S3UA 3S3VA 4KY4A 4I13A 3QG2A 4P68A 3NXRA 3EEJA 3I8AX 4KYAA 3TQAA 1HFQA 3SRWX 1DR4A 3JWMA 1DYRA 4H98A 1RA9A 4TU5X 5CCCA 3SA1A 4XRBA 4ELGA 3DL6A 5HF2X 3ROAA 3JVXA 3K45A 2BLBA 2JYBA 1KMVA 3FRBX 3FL9A 4IXED 1DG7A 3S7AA 5HVEA 1QZFA 3NZAX 1RB3A 3R33A 1RG7A 3SGYA 4ECKA 3DFRA 4X5IA 4NX6A 1M78A 4HOEA 4FHBA 4KJJA 3K2HA 4ELBA 1DR6A 3F0QX 2INQA 4PSYA 5EAJA 4PDJA 3SRUX 1CD2A 1DDRA 3TQBA 3GHVA 6DFRA 2HQPA 1JUVA 1RX1A 3D80A 4H96A 4NX7A 2CD2A 2HXVA 3FRFX 3TQ9A 2QK8A 3F8ZA 4LEKX 3FRAX 1RX4A 1DF7A 3Q1HA 1MVTA 1RA2A 1TDRA 5JG0X 1RF7A 4M7VA 4ELFA 3FQCA 3JW5A 1DYIA 3QL3A 4KM2A 3EELA 3TD8A 3VCOA 1BZFA 3SAIA 1S3VA 3NU0A 2FZHA 5DXVA 3K47A 1DLRA 2W3BA 1VJ3A 1OHKA 3FRDX 2LF1A 1JOLA 3QYLA 4G95A 3HBBA 3FYVX 5ECCA 4FGGA 3GYFA 5HUIA 3SH2A 1DR1A 1U71A 4P66A 5HI6A 5DFRA 5HSUA 3SA2A 1IA2A 3F91A 2KGKA 1DR5A 3EIGA 7DFRA 1JOMA 4HOGA 4Q67A 1HFRA 1VDRA 4XECX 3F8YA 1M7AA 4KNEA 3EX8A 3FY9X 4QJZD 2W9HA 2W3MA 3DG8A 1DISA 1DYHA 5HT5A 4EIZA 3UM8A 4EIGA 3F0VX 2BL9A 4QHVA 4EJ1A 1RC4A 1PD9A 2W9GA 4GH8A 4IXFX 3F0BX 3GI2A 1RX9A 1ZDRA 4KJLA 4KL9A 1RX7A 1YHOA 3F0SX 5FDAA 2B3ZA 3QGTA 1DRBA 4M2XA 2BLAA 3JWKA 1DRFA 4QLGA 1S3WA 1KLKA 3CLBA 3QLYA 4P3RA 3FQFA 4HA7A 3GHCA 4OSGA 5E8QA 1E26A 3QLZA 4KM0A 4KAKA 3CSEA 4G8ZX 1IA1A 3QLXA 3UM5A 3NXYA 4PTJA 4XT7A 3IRNA 3QFXA 1DG5A 4XT6A 1RA8A 5CC9A 3SRSX 3LG4A 3ZPGA 3NXOA 3CD2A 1DRAA 1J3KA 2ZZAA 3S9UA 3M08A 1MVSA 3HJ3A 4XT5A 2W3VA 1KMSA 3NZ9X 2DHFA 2C2TA
chains in the Genus database with same CATH topology
2W3AA 5U27A 3K74A 3FQVA 5HSRA 1LY3A 2DRCA 3DATA 2ANQA 4P3QA 3IROA 4QLEA 4X5JA 3SRQX 4ELHA 3NZDA 1DREA 4Q0DA 1LUDA 3D84X 1DR3A 2BLCA 2D5NA 2H2QA 2ITHA 3EEKA 1RX8A 4ELEA 2FZJA 3NZ6X 4RGCA 1DR7A 1DR2A 2W9TA 4DPDA 1RB2A 2GD9A 3NRRA 1PD8A 1CZ3A 1M79A 3EEMA 3FL8A 3FQZA 4M6KA 3JWCA 4I1NA 4DPHA 4H97A 1J3JA 2OIPA 4FGHA 2W3WA 3INVA 3NXVA 2G6VA 1RX5A 1AOEA 3OCHA 4PSSA 4CD2A 3JWFA 1IA3A 3SQYX 2O7PA 4EILA 1RA1A 2ANOA 3F0XX 3IRMA 3JW3A 4XT8A 3KY8A 5HQZA 3KJRA 3QLWA 5HT4A 2W9SA 2P4GA 1SEJA 5HVBA 4X5HA 2D0KA 3M09A 3IA4A 1RA3A 1J3IA 1DHJA 3IX9A 1AO8A 4QJCA 3FYWX 4M6LA 4KJKA 4IXGX 4H95A 3TQ8A 2XW7A 3L3RA 4KLXA 3FY8X 1RX3A 1DHFA 3E0BA 4G3MA 3F0UX 4HOFA 4M7UA 2C2SA 1S3YA 4QLFA 3JSUA 4HA9A 4XE6X 3DRCA 3SR5X 4LAEX 1RX6A 1LY4A 1OHJA 2AZNA 3UM6A 1D1GA 3FQOA 3QL0A 4XT4A 3N0HA 5HQYA 4OR7A 3QLSA 4DFRA 1DIUA 5JA3A 4KD7A 3KJSA 3KFYA 2HM9A 1BOZA 3GHWA 2L28A 3NXTA 1RD7A 3QLRA 1RH3A 3DGAA 5HPBA 1U72A 2FZIA 4X5GA 2CIGA 1DLSA 3FQ0A 4LAGX 3I3RA 5U26A 4KEBA 3KGYA 3RG9A 4KFJA 4PTHA 3NTZA 4KY8A 1U70A 5HF0X 3IA5A 3OAFA 3FREX 4PSTA 5ECXA 3QYOA 3NXXA 3DL5A 4Q0EA 4DP3A 3CL9A 8DFRA 1DAJA 1IA4A 4M6JA 3NZBX 1DYJA 3NZCX 4Q6AA 1PDBA 3FS6A 4LAHX 1DRHA 4DDRA 1DHIA 1RX2A 4X5FA 3RO9A 1AI9A 1HFPA 1RE7A 3DAUA 3JTWA 4KBNA 1DDSA 3ZPCA 2OBCA 4QI9A 3SRRX 1DG8A 1S3UA 3S3VA 4KY4A 4I13A 3QG2A 4P68A 3NXRA 3EEJA 3I8AX 4KYAA 3TQAA 1HFQA 3SRWX 1DR4A 3JWMA 1DYRA 4H98A 1RA9A 4TU5X 5CCCA 3SA1A 4XRBA 4ELGA 3DL6A 5HF2X 3ROAA 3JVXA 3K45A 2BLBA 2JYBA 1KMVA 3FRBX 3FL9A 4IXED 1DG7A 3S7AA 5HVEA 1QZFA 3NZAX 1RB3A 3R33A 1RG7A 3SGYA 4ECKA 3DFRA 4X5IA 4NX6A 1M78A 4HOEA 4FHBA 4KJJA 3K2HA 4ELBA 1DR6A 3F0QX 2INQA 4PSYA 5EAJA 4PDJA 3SRUX 1CD2A 1DDRA 3TQBA 3GHVA 6DFRA 2HQPA 1JUVA 1RX1A 3D80A 4H96A 4NX7A 2CD2A 2HXVA 3FRFX 3TQ9A 2QK8A 3F8ZA 4LEKX 3FRAX 1RX4A 1DF7A 3Q1HA 1MVTA 1RA2A 1TDRA 5JG0X 1RF7A 4M7VA 4ELFA 3FQCA 3JW5A 1DYIA 3QL3A 4KM2A 3EELA 3TD8A 3VCOA 1BZFA 3SAIA 1S3VA 3NU0A 2FZHA 5DXVA 3K47A 1DLRA 2W3BA 1VJ3A 1OHKA 3FRDX 2LF1A 1JOLA 3QYLA 4G95A 3HBBA 3FYVX 5ECCA 4FGGA 3GYFA 5HUIA 3SH2A 1DR1A 1U71A 4P66A 5HI6A 5DFRA 5HSUA 3SA2A 1IA2A 3F91A 2KGKA 1DR5A 3EIGA 7DFRA 1JOMA 4HOGA 4Q67A 1HFRA 1VDRA 4XECX 3F8YA 1M7AA 4KNEA 3EX8A 3FY9X 4QJZD 2W9HA 2W3MA 3DG8A 1DISA 1DYHA 5HT5A 4EIZA 3UM8A 4EIGA 3F0VX 2BL9A 4QHVA 4EJ1A 1RC4A 1PD9A 2W9GA 4GH8A 4IXFX 3F0BX 3GI2A 1RX9A 1ZDRA 4KJLA 4KL9A 1RX7A 1YHOA 3F0SX 5FDAA 2B3ZA 3QGTA 1DRBA 4M2XA 2BLAA 3JWKA 1DRFA 4QLGA 1S3WA 1KLKA 3CLBA 3QLYA 4P3RA 3FQFA 4HA7A 3GHCA 4OSGA 5E8QA 1E26A 3QLZA 4KM0A 4KAKA 3CSEA 4G8ZX 1IA1A 3QLXA 3UM5A 3NXYA 4PTJA 4XT7A 3IRNA 3QFXA 1DG5A 4XT6A 1RA8A 5CC9A 3SRSX 3LG4A 3ZPGA 3NXOA 3CD2A 1DRAA 1J3KA 2ZZAA 3S9UA 3M08A 1MVSA 3HJ3A 4XT5A 2W3VA 1KMSA 3NZ9X 2DHFA 2C2TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W3A A;  5U27 A;  3K74 A;  3FQV A;  5HSR A;  1LY3 A;  2DRC A;  3DAT A;  2ANQ A;  4P3Q A;  3IRO A;  4QLE A;  4X5J A;  3SRQ X;  4ELH A;  3NZD A;  1DRE A;  4Q0D A;  1LUD A;  3D84 X;  1DR3 A;  2BLC A;  2D5N A;  2H2Q A;  2ITH A;  3EEK A;  1RX8 A;  4ELE A;  2FZJ A;  3NZ6 X;  4RGC A;  1DR7 A;  1DR2 A;  2W9T A;  4DPD A;  1RB2 A;  2GD9 A;  3NRR A;  1PD8 A;  1CZ3 A;  1M79 A;  3EEM A;  3FL8 A;  3FQZ A;  4M6K A;  3JWC A;  4I1N A;  4DPH A;  4H97 A;  1J3J A;  2OIP A;  4FGH A;  2W3W A;  3INV A;  3NXV A;  2G6V A;  1RX5 A;  1AOE A;  3OCH A;  4PSS A;  4CD2 A;  3JWF A;  1IA3 A;  3SQY X;  2O7P A;  4EIL A;  1RA1 A;  2ANO A;  3F0X X;  3IRM A;  3JW3 A;  4XT8 A;  3KY8 A;  5HQZ A;  3KJR A;  3QLW A;  5HT4 A;  2W9S A;  2P4G A;  1SEJ A;  5HVB A;  4X5H A;  2D0K A;  3M09 A;  3IA4 A;  1RA3 A;  1J3I A;  1DHJ A;  3IX9 A;  1AO8 A;  4QJC A;  3FYW X;  4M6L A;  4KJK A;  4IXG X;  4H95 A;  3TQ8 A;  2XW7 A;  3L3R A;  4KLX A;  3FY8 X;  1RX3 A;  1DHF A;  3E0B A;  4G3M A;  3F0U X;  4HOF A;  4M7U A;  2C2S A;  1S3Y A;  4QLF A;  3JSU A;  4HA9 A;  4XE6 X;  3DRC A;  3SR5 X;  4LAE X;  1RX6 A;  1LY4 A;  1OHJ A;  2AZN A;  3UM6 A;  1D1G A;  3FQO A;  3QL0 A;  4XT4 A;  3N0H A;  5HQY A;  4OR7 A;  3QLS A;  4DFR A;  1DIU A;  5JA3 A;  4KD7 A;  3KJS A;  3KFY A;  2HM9 A;  1BOZ A;  3GHW A;  2L28 A;  3NXT A;  1RD7 A;  3QLR A;  1RH3 A;  3DGA A;  5HPB A;  1U72 A;  2FZI A;  4X5G A;  2CIG A;  1DLS A;  3FQ0 A;  4LAG X;  3I3R A;  5U26 A;  4KEB A;  3KGY A;  3RG9 A;  4KFJ A;  4PTH A;  3NTZ A;  4KY8 A;  1U70 A;  5HF0 X;  3IA5 A;  3OAF A;  3FRE X;  4PST A;  5ECX A;  3QYO A;  3NXX A;  3DL5 A;  4Q0E A;  4DP3 A;  3CL9 A;  8DFR A;  1DAJ A;  1IA4 A;  4M6J A;  3NZB X;  1DYJ A;  3NZC X;  4Q6A A;  1PDB A;  3FS6 A;  4LAH X;  1DRH A;  4DDR A;  1DHI A;  1RX2 A;  4X5F A;  3RO9 A;  1AI9 A;  1HFP A;  1RE7 A;  3DAU A;  3JTW A;  4KBN A;  1DDS A;  3ZPC A;  2OBC A;  4QI9 A;  3SRR X;  1DG8 A;  1S3U A;  3S3V A;  4KY4 A;  4I13 A;  3QG2 A;  4P68 A;  3NXR A;  3EEJ A;  3I8A X;  4KYA A;  3TQA A;  1HFQ A;  3SRW X;  1DR4 A;  3JWM A;  1DYR A;  4H98 A;  1RA9 A;  4TU5 X;  5CCC A;  3SA1 A;  4XRB A;  4ELG A;  3DL6 A;  5HF2 X;  3ROA A;  3JVX A;  3K45 A;  2BLB A;  2JYB A;  1KMV A;  3FRB X;  3FL9 A;  4IXE D;  1DG7 A;  3S7A A;  5HVE A;  1QZF A;  3NZA X;  1RB3 A;  3R33 A;  1RG7 A;  3SGY A;  4ECK A;  3DFR A;  4X5I A;  4NX6 A;  1M78 A;  4HOE A;  4FHB A;  4KJJ A;  3K2H A;  4ELB A;  1DR6 A;  3F0Q X;  2INQ A;  4PSY A;  5EAJ A;  4PDJ A;  3SRU X;  1CD2 A;  1DDR A;  3TQB A;  3GHV A;  6DFR A;  2HQP A;  1JUV A;  1RX1 A;  3D80 A;  4H96 A;  4NX7 A;  2CD2 A;  2HXV A;  3FRF X;  3TQ9 A;  2QK8 A;  3F8Z A;  4LEK X;  3FRA X;  1RX4 A;  1DF7 A;  3Q1H A;  1MVT A;  1RA2 A;  1TDR A;  5JG0 X;  1RF7 A;  4M7V A;  4ELF A;  3FQC A;  3JW5 A;  1DYI A;  3QL3 A;  4KM2 A;  3EEL A;  3TD8 A;  3VCO A;  1BZF A;  3SAI A;  1S3V A;  3NU0 A;  2FZH A;  5DXV A;  3K47 A;  1DLR A;  2W3B A;  1VJ3 A;  1OHK A;  3FRD X;  2LF1 A;  1JOL A;  3QYL A;  4G95 A;  3HBB A;  3FYV X;  5ECC A;  4FGG A;  3GYF A;  5HUI A;  3SH2 A;  1DR1 A;  1U71 A;  4P66 A;  5HI6 A;  5DFR A;  5HSU A;  3SA2 A;  1IA2 A;  3F91 A;  2KGK A;  1DR5 A;  3EIG A;  7DFR A;  1JOM A;  4HOG A;  4Q67 A;  1HFR A;  1VDR A;  4XEC X;  3F8Y A;  1M7A A;  4KNE A;  3EX8 A;  3FY9 X;  4QJZ D;  2W9H A;  2W3M A;  3DG8 A;  1DIS A;  1DYH A;  5HT5 A;  4EIZ A;  3UM8 A;  4EIG A;  3F0V X;  2BL9 A;  4QHV A;  4EJ1 A;  1RC4 A;  1PD9 A;  2W9G A;  4GH8 A;  4IXF X;  3F0B X;  3GI2 A;  1RX9 A;  1ZDR A;  4KJL A;  4KL9 A;  1RX7 A;  1YHO A;  3F0S X;  5FDA A;  2B3Z A;  3QGT A;  1DRB A;  4M2X A;  2BLA A;  3JWK A;  1DRF A;  4QLG A;  1S3W A;  1KLK A;  3CLB A;  3QLY A;  4P3R A;  3FQF A;  4HA7 A;  3GHC A;  4OSG A;  5E8Q A;  1E26 A;  3QLZ A;  4KM0 A;  4KAK A;  3CSE A;  4G8Z X;  1IA1 A;  3QLX A;  3UM5 A;  3NXY A;  4PTJ A;  4XT7 A;  3IRN A;  3QFX A;  1DG5 A;  4XT6 A;  1RA8 A;  5CC9 A;  3SRS X;  3LG4 A;  3ZPG A;  3NXO A;  3CD2 A;  1DRA A;  1J3K A;  2ZZA A;  3S9U A;  3M08 A;  1MVS A;  3HJ3 A;  4XT5 A;  2W3V A;  1KMS A;  3NZ9 X;  2DHF A;  2C2T A; 
#chains in the Genus database with same CATH topology
 2W3A A;  5U27 A;  3K74 A;  3FQV A;  5HSR A;  1LY3 A;  2DRC A;  3DAT A;  2ANQ A;  4P3Q A;  3IRO A;  4QLE A;  4X5J A;  3SRQ X;  4ELH A;  3NZD A;  1DRE A;  4Q0D A;  1LUD A;  3D84 X;  1DR3 A;  2BLC A;  2D5N A;  2H2Q A;  2ITH A;  3EEK A;  1RX8 A;  4ELE A;  2FZJ A;  3NZ6 X;  4RGC A;  1DR7 A;  1DR2 A;  2W9T A;  4DPD A;  1RB2 A;  2GD9 A;  3NRR A;  1PD8 A;  1CZ3 A;  1M79 A;  3EEM A;  3FL8 A;  3FQZ A;  4M6K A;  3JWC A;  4I1N A;  4DPH A;  4H97 A;  1J3J A;  2OIP A;  4FGH A;  2W3W A;  3INV A;  3NXV A;  2G6V A;  1RX5 A;  1AOE A;  3OCH A;  4PSS A;  4CD2 A;  3JWF A;  1IA3 A;  3SQY X;  2O7P A;  4EIL A;  1RA1 A;  2ANO A;  3F0X X;  3IRM A;  3JW3 A;  4XT8 A;  3KY8 A;  5HQZ A;  3KJR A;  3QLW A;  5HT4 A;  2W9S A;  2P4G A;  1SEJ A;  5HVB A;  4X5H A;  2D0K A;  3M09 A;  3IA4 A;  1RA3 A;  1J3I A;  1DHJ A;  3IX9 A;  1AO8 A;  4QJC A;  3FYW X;  4M6L A;  4KJK A;  4IXG X;  4H95 A;  3TQ8 A;  2XW7 A;  3L3R A;  4KLX A;  3FY8 X;  1RX3 A;  1DHF A;  3E0B A;  4G3M A;  3F0U X;  4HOF A;  4M7U A;  2C2S A;  1S3Y A;  4QLF A;  3JSU A;  4HA9 A;  4XE6 X;  3DRC A;  3SR5 X;  4LAE X;  1RX6 A;  1LY4 A;  1OHJ A;  2AZN A;  3UM6 A;  1D1G A;  3FQO A;  3QL0 A;  4XT4 A;  3N0H A;  5HQY A;  4OR7 A;  3QLS A;  4DFR A;  1DIU A;  5JA3 A;  4KD7 A;  3KJS A;  3KFY A;  2HM9 A;  1BOZ A;  3GHW A;  2L28 A;  3NXT A;  1RD7 A;  3QLR A;  1RH3 A;  3DGA A;  5HPB A;  1U72 A;  2FZI A;  4X5G A;  2CIG A;  1DLS A;  3FQ0 A;  4LAG X;  3I3R A;  5U26 A;  4KEB A;  3KGY A;  3RG9 A;  4KFJ A;  4PTH A;  3NTZ A;  4KY8 A;  1U70 A;  5HF0 X;  3IA5 A;  3OAF A;  3FRE X;  4PST A;  5ECX A;  3QYO A;  3NXX A;  3DL5 A;  4Q0E A;  4DP3 A;  3CL9 A;  8DFR A;  1DAJ A;  1IA4 A;  4M6J A;  3NZB X;  1DYJ A;  3NZC X;  4Q6A A;  1PDB A;  3FS6 A;  4LAH X;  1DRH A;  4DDR A;  1DHI A;  1RX2 A;  4X5F A;  3RO9 A;  1AI9 A;  1HFP A;  1RE7 A;  3DAU A;  3JTW A;  4KBN A;  1DDS A;  3ZPC A;  2OBC A;  4QI9 A;  3SRR X;  1DG8 A;  1S3U A;  3S3V A;  4KY4 A;  4I13 A;  3QG2 A;  4P68 A;  3NXR A;  3EEJ A;  3I8A X;  4KYA A;  3TQA A;  1HFQ A;  3SRW X;  1DR4 A;  3JWM A;  1DYR A;  4H98 A;  1RA9 A;  4TU5 X;  5CCC A;  3SA1 A;  4XRB A;  4ELG A;  3DL6 A;  5HF2 X;  3ROA A;  3JVX A;  3K45 A;  2BLB A;  2JYB A;  1KMV A;  3FRB X;  3FL9 A;  4IXE D;  1DG7 A;  3S7A A;  5HVE A;  1QZF A;  3NZA X;  1RB3 A;  3R33 A;  1RG7 A;  3SGY A;  4ECK A;  3DFR A;  4X5I A;  4NX6 A;  1M78 A;  4HOE A;  4FHB A;  4KJJ A;  3K2H A;  4ELB A;  1DR6 A;  3F0Q X;  2INQ A;  4PSY A;  5EAJ A;  4PDJ A;  3SRU X;  1CD2 A;  1DDR A;  3TQB A;  3GHV A;  6DFR A;  2HQP A;  1JUV A;  1RX1 A;  3D80 A;  4H96 A;  4NX7 A;  2CD2 A;  2HXV A;  3FRF X;  3TQ9 A;  2QK8 A;  3F8Z A;  4LEK X;  3FRA X;  1RX4 A;  1DF7 A;  3Q1H A;  1MVT A;  1RA2 A;  1TDR A;  5JG0 X;  1RF7 A;  4M7V A;  4ELF A;  3FQC A;  3JW5 A;  1DYI A;  3QL3 A;  4KM2 A;  3EEL A;  3TD8 A;  3VCO A;  1BZF A;  3SAI A;  1S3V A;  3NU0 A;  2FZH A;  5DXV A;  3K47 A;  1DLR A;  2W3B A;  1VJ3 A;  1OHK A;  3FRD X;  2LF1 A;  1JOL A;  3QYL A;  4G95 A;  3HBB A;  3FYV X;  5ECC A;  4FGG A;  3GYF A;  5HUI A;  3SH2 A;  1DR1 A;  1U71 A;  4P66 A;  5HI6 A;  5DFR A;  5HSU A;  3SA2 A;  1IA2 A;  3F91 A;  2KGK A;  1DR5 A;  3EIG A;  7DFR A;  1JOM A;  4HOG A;  4Q67 A;  1HFR A;  1VDR A;  4XEC X;  3F8Y A;  1M7A A;  4KNE A;  3EX8 A;  3FY9 X;  4QJZ D;  2W9H A;  2W3M A;  3DG8 A;  1DIS A;  1DYH A;  5HT5 A;  4EIZ A;  3UM8 A;  4EIG A;  3F0V X;  2BL9 A;  4QHV A;  4EJ1 A;  1RC4 A;  1PD9 A;  2W9G A;  4GH8 A;  4IXF X;  3F0B X;  3GI2 A;  1RX9 A;  1ZDR A;  4KJL A;  4KL9 A;  1RX7 A;  1YHO A;  3F0S X;  5FDA A;  2B3Z A;  3QGT A;  1DRB A;  4M2X A;  2BLA A;  3JWK A;  1DRF A;  4QLG A;  1S3W A;  1KLK A;  3CLB A;  3QLY A;  4P3R A;  3FQF A;  4HA7 A;  3GHC A;  4OSG A;  5E8Q A;  1E26 A;  3QLZ A;  4KM0 A;  4KAK A;  3CSE A;  4G8Z X;  1IA1 A;  3QLX A;  3UM5 A;  3NXY A;  4PTJ A;  4XT7 A;  3IRN A;  3QFX A;  1DG5 A;  4XT6 A;  1RA8 A;  5CC9 A;  3SRS X;  3LG4 A;  3ZPG A;  3NXO A;  3CD2 A;  1DRA A;  1J3K A;  2ZZA A;  3S9U A;  3M08 A;  1MVS A;  3HJ3 A;  4XT5 A;  2W3V A;  1KMS A;  3NZ9 X;  2DHF A;  2C2T A; 
#chains in the Genus database with same CATH homology
 2W3A A;  5U27 A;  3K74 A;  3FQV A;  5HSR A;  1LY3 A;  2DRC A;  3DAT A;  2ANQ A;  4P3Q A;  3IRO A;  4QLE A;  4X5J A;  3SRQ X;  4ELH A;  3NZD A;  1DRE A;  4Q0D A;  1LUD A;  3D84 X;  1DR3 A;  2BLC A;  2D5N A;  2H2Q A;  2ITH A;  3EEK A;  1RX8 A;  4ELE A;  2FZJ A;  3NZ6 X;  4RGC A;  1DR7 A;  1DR2 A;  2W9T A;  4DPD A;  1RB2 A;  2GD9 A;  3NRR A;  1PD8 A;  1CZ3 A;  1M79 A;  3EEM A;  3FL8 A;  3FQZ A;  4M6K A;  3JWC A;  4I1N A;  4DPH A;  4H97 A;  1J3J A;  2OIP A;  4FGH A;  2W3W A;  3INV A;  3NXV A;  2G6V A;  1RX5 A;  1AOE A;  3OCH A;  4PSS A;  4CD2 A;  3JWF A;  1IA3 A;  3SQY X;  2O7P A;  4EIL A;  1RA1 A;  2ANO A;  3F0X X;  3IRM A;  3JW3 A;  4XT8 A;  3KY8 A;  5HQZ A;  3KJR A;  3QLW A;  5HT4 A;  2W9S A;  2P4G A;  1SEJ A;  5HVB A;  4X5H A;  2D0K A;  3M09 A;  3IA4 A;  1RA3 A;  1J3I A;  1DHJ A;  3IX9 A;  1AO8 A;  4QJC A;  3FYW X;  4M6L A;  4KJK A;  4IXG X;  4H95 A;  3TQ8 A;  2XW7 A;  3L3R A;  4KLX A;  3FY8 X;  1RX3 A;  1DHF A;  3E0B A;  4G3M A;  3F0U X;  4HOF A;  4M7U A;  2C2S A;  1S3Y A;  4QLF A;  3JSU A;  4HA9 A;  4XE6 X;  3DRC A;  3SR5 X;  4LAE X;  1RX6 A;  1LY4 A;  1OHJ A;  2AZN A;  3UM6 A;  1D1G A;  3FQO A;  3QL0 A;  4XT4 A;  3N0H A;  5HQY A;  4OR7 A;  3QLS A;  4DFR A;  1DIU A;  5JA3 A;  4KD7 A;  3KJS A;  3KFY A;  2HM9 A;  1BOZ A;  3GHW A;  2L28 A;  3NXT A;  1RD7 A;  3QLR A;  1RH3 A;  3DGA A;  5HPB A;  1U72 A;  2FZI A;  4X5G A;  2CIG A;  1DLS A;  3FQ0 A;  4LAG X;  3I3R A;  5U26 A;  4KEB A;  3KGY A;  3RG9 A;  4KFJ A;  4PTH A;  3NTZ A;  4KY8 A;  1U70 A;  5HF0 X;  3IA5 A;  3OAF A;  3FRE X;  4PST A;  5ECX A;  3QYO A;  3NXX A;  3DL5 A;  4Q0E A;  4DP3 A;  3CL9 A;  8DFR A;  1DAJ A;  1IA4 A;  4M6J A;  3NZB X;  1DYJ A;  3NZC X;  4Q6A A;  1PDB A;  3FS6 A;  4LAH X;  1DRH A;  4DDR A;  1DHI A;  1RX2 A;  4X5F A;  3RO9 A;  1AI9 A;  1HFP A;  1RE7 A;  3DAU A;  3JTW A;  4KBN A;  1DDS A;  3ZPC A;  2OBC A;  4QI9 A;  3SRR X;  1DG8 A;  1S3U A;  3S3V A;  4KY4 A;  4I13 A;  3QG2 A;  4P68 A;  3NXR A;  3EEJ A;  3I8A X;  4KYA A;  3TQA A;  1HFQ A;  3SRW X;  1DR4 A;  3JWM A;  1DYR A;  4H98 A;  1RA9 A;  4TU5 X;  5CCC A;  3SA1 A;  4XRB A;  4ELG A;  3DL6 A;  5HF2 X;  3ROA A;  3JVX A;  3K45 A;  2BLB A;  2JYB A;  1KMV A;  3FRB X;  3FL9 A;  4IXE D;  1DG7 A;  3S7A A;  5HVE A;  1QZF A;  3NZA X;  1RB3 A;  3R33 A;  1RG7 A;  3SGY A;  4ECK A;  3DFR A;  4X5I A;  4NX6 A;  1M78 A;  4HOE A;  4FHB A;  4KJJ A;  3K2H A;  4ELB A;  1DR6 A;  3F0Q X;  2INQ A;  4PSY A;  5EAJ A;  4PDJ A;  3SRU X;  1CD2 A;  1DDR A;  3TQB A;  3GHV A;  6DFR A;  2HQP A;  1JUV A;  1RX1 A;  3D80 A;  4H96 A;  4NX7 A;  2CD2 A;  2HXV A;  3FRF X;  3TQ9 A;  2QK8 A;  3F8Z A;  4LEK X;  3FRA X;  1RX4 A;  1DF7 A;  3Q1H A;  1MVT A;  1RA2 A;  1TDR A;  5JG0 X;  1RF7 A;  4M7V A;  4ELF A;  3FQC A;  3JW5 A;  1DYI A;  3QL3 A;  4KM2 A;  3EEL A;  3TD8 A;  3VCO A;  1BZF A;  3SAI A;  1S3V A;  3NU0 A;  2FZH A;  5DXV A;  3K47 A;  1DLR A;  2W3B A;  1VJ3 A;  1OHK A;  3FRD X;  2LF1 A;  1JOL A;  3QYL A;  4G95 A;  3HBB A;  3FYV X;  5ECC A;  4FGG A;  3GYF A;  5HUI A;  3SH2 A;  1DR1 A;  1U71 A;  4P66 A;  5HI6 A;  5DFR A;  5HSU A;  3SA2 A;  1IA2 A;  3F91 A;  2KGK A;  1DR5 A;  3EIG A;  7DFR A;  1JOM A;  4HOG A;  4Q67 A;  1HFR A;  1VDR A;  4XEC X;  3F8Y A;  1M7A A;  4KNE A;  3EX8 A;  3FY9 X;  4QJZ D;  2W9H A;  2W3M A;  3DG8 A;  1DIS A;  1DYH A;  5HT5 A;  4EIZ A;  3UM8 A;  4EIG A;  3F0V X;  2BL9 A;  4QHV A;  4EJ1 A;  1RC4 A;  1PD9 A;  2W9G A;  4GH8 A;  4IXF X;  3F0B X;  3GI2 A;  1RX9 A;  1ZDR A;  4KJL A;  4KL9 A;  1RX7 A;  1YHO A;  3F0S X;  5FDA A;  2B3Z A;  3QGT A;  1DRB A;  4M2X A;  2BLA A;  3JWK A;  1DRF A;  4QLG A;  1S3W A;  1KLK A;  3CLB A;  3QLY A;  4P3R A;  3FQF A;  4HA7 A;  3GHC A;  4OSG A;  5E8Q A;  1E26 A;  3QLZ A;  4KM0 A;  4KAK A;  3CSE A;  4G8Z X;  1IA1 A;  3QLX A;  3UM5 A;  3NXY A;  4PTJ A;  4XT7 A;  3IRN A;  3QFX A;  1DG5 A;  4XT6 A;  1RA8 A;  5CC9 A;  3SRS X;  3LG4 A;  3ZPG A;  3NXO A;  3CD2 A;  1DRA A;  1J3K A;  2ZZA A;  3S9U A;  3M08 A;  1MVS A;  3HJ3 A;  4XT5 A;  2W3V A;  1KMS A;  3NZ9 X;  2DHF A;  2C2T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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