1RC4A

Dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and nicotinamide adenine dinucleotide phosphate (oxidized form)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 40
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rc4A00
1DYJA 1RX3A 4KAKA 3UM6A 4XT8A 3IX9A 4Q0EA 1RX7A 3NXXA 5DFRA 5EAJA 4CD2A 2W9TA 3UM5A 1DDSA 1HFRA 3TQAA 3SRUX 3NZCX 1DR7A 1S3YA 1YHOA 1DYIA 3FYVX 2B3ZA 5HSRA 1DISA 1RX8A 4XT5A 1JOMA 2OIPA 3ZPCA 2BL9A 5U26A 3NZAX 2W9GA 1DAJA 3K47A 1S3VA 3JTWA 2FZHA 7DFRA 5HT5A 4NX7A 1M79A 1DR2A 5ECXA 1OHJA 3KY8A 4KEBA 2BLAA 3QLXA 3JWFA 3NXTA 1E26A 3NU0A 1DG7A 2XW7A 1DLRA 1HFPA 4KY4A 2O7PA 3SA1A 4X5FA 3EEJA 3QFXA 4P3QA 3M08A 4FGHA 1J3IA 4HA7A 4XT6A 2D5NA 2ANQA 3ROAA 3DL6A 1DLSA 3D84X 3UM8A 2H2QA 4XECX 3SRSX 5CCCA 4X5IA 1IA2A 4KJKA 2GD9A 3DFRA 1RX9A 3SAIA 2OBCA 4ECKA 3RG9A 3QGTA 4PSSA 1RH3A 3F8YA 2DRCA 3QYLA 3F0SX 4QLGA 3FQCA 3KFYA 5HF2X 1BZFA 1S3UA 3KJSA 4Q0DA 3S3VA 3GYFA 1DIUA 3QLZA 3FYWX 8DFRA 3F91A 3DRCA 4P68A 5HI6A 1RA9A 4HOFA 4LEKX 1MVTA 3JVXA 3M09A 3NZBX 5HPBA 4EIGA 1RF7A 3JWMA 1AO8A 4M7UA 1DRFA 3FL8A 3DG8A 1JUVA 1DRAA 4HOGA 2AZNA 1D1GA 3FRDX 1DG5A 4LAGX 4EILA 4DDRA 3DL5A 2C2SA 3F8ZA 2D0KA 4TU5X 3TQ8A 4QJCA 3NXYA 4P3RA 3EEKA 4Q67A 2W3BA 1PDBA 5HT4A 3FY8X 4M2XA 4KYAA 3K45A 4X5GA 1JOLA 1RB2A 1RX5A 3NXVA 1DR4A 4X5JA 3FQZA 3OAFA 4DPHA 2W3AA 4XE6X 3FQVA 4H95A 3F0UX 1HFQA 4ELBA 3SR5X 2W9SA 1DR1A 4LAEX 4QHVA 4IXFX 4PSYA 1RX6A 1DHFA 3TQ9A 4XT7A 3QLWA 1DF7A 1RX2A 2L28A 1KMVA 3GHCA 1RA8A 3EELA 3NZDA 3JW5A 3SGYA 4QI9A 1IA4A 3IRNA 2CD2A 3FQOA 3GI2A 3E0BA 3VCOA 1RD7A 3FRBX 5JA3A 4IXGX 3SRRX 4LAHX 1DHJA 1LUDA 3TQBA 4KLXA 4PDJA 5HQZA 3CD2A 4IXED 1M78A 3KGYA 4XRBA 2ZZAA 1ZDRA 3DAUA 1VDRA 3OCHA 3TD8A 1AOEA 1RG7A 4EJ1A 2W3VA 1RA3A 2BLBA 3FS6A 3EX8A 4FHBA 3QL3A 3F0QX 1DRHA 4FGGA 3GHWA 2C2TA 5HVEA 3NTZA 1RA1A 1RE7A 4G3MA 3JSUA 5HF0X 3IROA 1U70A 3FRAX 1DR6A 3CLBA 3Q1HA 5FDAA 4XT4A 1VJ3A 1RX4A 5HSUA 4Q6AA 2W3MA 3KJRA 2HM9A 3NXOA 3QL0A 4ELHA 1RC4A 3FREX 3D80A 5HVBA 3HJ3A 4NX6A 3QYOA 3HBBA 3I3RA 1M7AA 3R33A 4DPDA 1DYHA 1CD2A 3NXRA 6DFRA 4GH8A 3JWKA 4DP3A 1J3KA 3NZ6X 3JW3A 1DR5A 3FRFX 3FQ0A 3CSEA 3EIGA 5ECCA 3GHVA 3JWCA 3FY9X 1QZFA 2CIGA 1DREA 4QLEA 4EIZA 4KM0A 4HA9A 3CL9A 2FZJA 1DG8A 3F0XX 1IA3A 3QLYA 1U72A 3I8AX 4KY8A 4KL9A 5E8QA 4KM2A 4PTHA 3EEMA 2LF1A 1IA1A 1MVSA 3SA2A 1LY3A 4H96A 4KBNA 3S9UA 1J3JA 3FL9A 1PD8A 4ELEA 1DYRA 3F0VX 4ELGA 5HUIA 4QJZD 3F0BX 1DR3A 4QLFA 1RB3A 4KJJA 3INVA 2G6VA 2DHFA 3ZPGA 4I1NA 3IRMA 4DFRA 2KGKA 1AI9A 4M6KA 5JG0X 1OHKA 3QLRA 1DRBA 2HQPA 4H98A 1KMSA 3SQYX 4ELFA 4G95A 4X5HA 3N0HA 2BLCA 2JYBA 3IA5A 1TDRA 3DATA 1RX1A 1PD9A 1U71A 4M6LA 2ITHA 2P4GA 3QG2A 1CZ3A 2W3WA 3DGAA 3K2HA 5HQYA 2W9HA 5U27A 4OSGA 3LG4A 2QK8A 1LY4A 3IA4A 4G8ZX 5CC9A 4RGCA 3SRQX 3SRWX 1SEJA 4OR7A 5DXVA 4KD7A 4P66A 3RO9A 4I13A 1BOZA 1RA2A 3FQFA 4KNEA 4M7VA 3NRRA 3S7AA 4HOEA 2FZIA 4KFJA 4M6JA 2INQA 1S3WA 2ANOA 4KJLA 3K74A 3L3RA 2HXVA 4H97A 4PTJA 3QLSA 1KLKA 1DHIA 4PSTA 3NZ9X 3SH2A 1DDRA
chains in the Genus database with same CATH superfamily
1DYJA 1RX3A 4KAKA 3UM6A 4XT8A 3IX9A 4Q0EA 1RX7A 3NXXA 5DFRA 5EAJA 4CD2A 2W9TA 3UM5A 1DDSA 1HFRA 3TQAA 3SRUX 3NZCX 1DR7A 1S3YA 1YHOA 1DYIA 3FYVX 2B3ZA 5HSRA 1DISA 1RX8A 4XT5A 1JOMA 2OIPA 3ZPCA 2BL9A 5U26A 3NZAX 2W9GA 1DAJA 3K47A 1S3VA 3JTWA 2FZHA 7DFRA 5HT5A 4NX7A 1M79A 1DR2A 5ECXA 1OHJA 3KY8A 4KEBA 2BLAA 3QLXA 3JWFA 3NXTA 1E26A 3NU0A 1DG7A 2XW7A 1DLRA 1HFPA 4KY4A 2O7PA 3SA1A 4X5FA 3EEJA 3QFXA 4P3QA 3M08A 4FGHA 1J3IA 4HA7A 4XT6A 2D5NA 2ANQA 3ROAA 3DL6A 1DLSA 3D84X 3UM8A 2H2QA 4XECX 3SRSX 5CCCA 4X5IA 1IA2A 4KJKA 2GD9A 3DFRA 1RX9A 3SAIA 2OBCA 4ECKA 3RG9A 3QGTA 4PSSA 1RH3A 3F8YA 2DRCA 3QYLA 3F0SX 4QLGA 3FQCA 3KFYA 5HF2X 1BZFA 1S3UA 3KJSA 4Q0DA 3S3VA 3GYFA 1DIUA 3QLZA 3FYWX 8DFRA 3F91A 3DRCA 4P68A 5HI6A 1RA9A 4HOFA 4LEKX 1MVTA 3JVXA 3M09A 3NZBX 5HPBA 4EIGA 1RF7A 3JWMA 1AO8A 4M7UA 1DRFA 3FL8A 3DG8A 1JUVA 1DRAA 4HOGA 2AZNA 1D1GA 3FRDX 1DG5A 4LAGX 4EILA 4DDRA 3DL5A 2C2SA 3F8ZA 2D0KA 4TU5X 3TQ8A 4QJCA 3NXYA 4P3RA 3EEKA 4Q67A 2W3BA 1PDBA 5HT4A 3FY8X 4M2XA 4KYAA 3K45A 4X5GA 1JOLA 1RB2A 1RX5A 3NXVA 1DR4A 4X5JA 3FQZA 3OAFA 4DPHA 2W3AA 4XE6X 3FQVA 4H95A 3F0UX 1HFQA 4ELBA 3SR5X 2W9SA 1DR1A 4LAEX 4QHVA 4IXFX 4PSYA 1RX6A 1DHFA 3TQ9A 4XT7A 3QLWA 1DF7A 1RX2A 2L28A 1KMVA 3GHCA 1RA8A 3EELA 3NZDA 3JW5A 3SGYA 4QI9A 1IA4A 3IRNA 2CD2A 3FQOA 3GI2A 3E0BA 3VCOA 1RD7A 3FRBX 5JA3A 4IXGX 3SRRX 4LAHX 1DHJA 1LUDA 3TQBA 4KLXA 4PDJA 5HQZA 3CD2A 4IXED 1M78A 3KGYA 4XRBA 2ZZAA 1ZDRA 3DAUA 1VDRA 3OCHA 3TD8A 1AOEA 1RG7A 4EJ1A 2W3VA 1RA3A 2BLBA 3FS6A 3EX8A 4FHBA 3QL3A 3F0QX 1DRHA 4FGGA 3GHWA 2C2TA 5HVEA 3NTZA 1RA1A 1RE7A 4G3MA 3JSUA 5HF0X 3IROA 1U70A 3FRAX 1DR6A 3CLBA 3Q1HA 5FDAA 4XT4A 1VJ3A 1RX4A 5HSUA 4Q6AA 2W3MA 3KJRA 2HM9A 3NXOA 3QL0A 4ELHA 1RC4A 3FREX 3D80A 5HVBA 3HJ3A 4NX6A 3QYOA 3HBBA 3I3RA 1M7AA 3R33A 4DPDA 1DYHA 1CD2A 3NXRA 6DFRA 4GH8A 3JWKA 4DP3A 1J3KA 3NZ6X 3JW3A 1DR5A 3FRFX 3FQ0A 3CSEA 3EIGA 5ECCA 3GHVA 3JWCA 3FY9X 1QZFA 2CIGA 1DREA 4QLEA 4EIZA 4KM0A 4HA9A 3CL9A 2FZJA 1DG8A 3F0XX 1IA3A 3QLYA 1U72A 3I8AX 4KY8A 4KL9A 5E8QA 4KM2A 4PTHA 3EEMA 2LF1A 1IA1A 1MVSA 3SA2A 1LY3A 4H96A 4KBNA 3S9UA 1J3JA 3FL9A 1PD8A 4ELEA 1DYRA 3F0VX 4ELGA 5HUIA 4QJZD 3F0BX 1DR3A 4QLFA 1RB3A 4KJJA 3INVA 2G6VA 2DHFA 3ZPGA 4I1NA 3IRMA 4DFRA 2KGKA 1AI9A 4M6KA 5JG0X 1OHKA 3QLRA 1DRBA 2HQPA 4H98A 1KMSA 3SQYX 4ELFA 4G95A 4X5HA 3N0HA 2BLCA 2JYBA 3IA5A 1TDRA 3DATA 1RX1A 1PD9A 1U71A 4M6LA 2ITHA 2P4GA 3QG2A 1CZ3A 2W3WA 3DGAA 3K2HA 5HQYA 2W9HA 5U27A 4OSGA 3LG4A 2QK8A 1LY4A 3IA4A 4G8ZX 5CC9A 4RGCA 3SRQX 3SRWX 1SEJA 4OR7A 5DXVA 4KD7A 4P66A 3RO9A 4I13A 1BOZA 1RA2A 3FQFA 4KNEA 4M7VA 3NRRA 3S7AA 4HOEA 2FZIA 4KFJA 4M6JA 2INQA 1S3WA 2ANOA 4KJLA 3K74A 3L3RA 2HXVA 4H97A 4PTJA 3QLSA 1KLKA 1DHIA 4PSTA 3NZ9X 3SH2A 1DDRA
chains in the Genus database with same CATH topology
1DYJA 1RX3A 4KAKA 3UM6A 4XT8A 3IX9A 4Q0EA 1RX7A 3NXXA 5DFRA 5EAJA 4CD2A 2W9TA 3UM5A 1DDSA 1HFRA 3TQAA 3SRUX 3NZCX 1DR7A 1S3YA 1YHOA 1DYIA 3FYVX 2B3ZA 5HSRA 1DISA 1RX8A 4XT5A 1JOMA 2OIPA 3ZPCA 2BL9A 5U26A 3NZAX 2W9GA 1DAJA 3K47A 1S3VA 3JTWA 2FZHA 7DFRA 5HT5A 4NX7A 1M79A 1DR2A 5ECXA 1OHJA 3KY8A 4KEBA 2BLAA 3QLXA 3JWFA 3NXTA 1E26A 3NU0A 1DG7A 2XW7A 1DLRA 1HFPA 4KY4A 2O7PA 3SA1A 4X5FA 3EEJA 3QFXA 4P3QA 3M08A 4FGHA 1J3IA 4HA7A 4XT6A 2D5NA 2ANQA 3ROAA 3DL6A 1DLSA 3D84X 3UM8A 2H2QA 4XECX 3SRSX 5CCCA 4X5IA 1IA2A 4KJKA 2GD9A 3DFRA 1RX9A 3SAIA 2OBCA 4ECKA 3RG9A 3QGTA 4PSSA 1RH3A 3F8YA 2DRCA 3QYLA 3F0SX 4QLGA 3FQCA 3KFYA 5HF2X 1BZFA 1S3UA 3KJSA 4Q0DA 3S3VA 3GYFA 1DIUA 3QLZA 3FYWX 8DFRA 3F91A 3DRCA 4P68A 5HI6A 1RA9A 4HOFA 4LEKX 1MVTA 3JVXA 3M09A 3NZBX 5HPBA 4EIGA 1RF7A 3JWMA 1AO8A 4M7UA 1DRFA 3FL8A 3DG8A 1JUVA 1DRAA 4HOGA 2AZNA 1D1GA 3FRDX 1DG5A 4LAGX 4EILA 4DDRA 3DL5A 2C2SA 3F8ZA 2D0KA 4TU5X 3TQ8A 4QJCA 3NXYA 4P3RA 3EEKA 4Q67A 2W3BA 1PDBA 5HT4A 3FY8X 4M2XA 4KYAA 3K45A 4X5GA 1JOLA 1RB2A 1RX5A 3NXVA 1DR4A 4X5JA 3FQZA 3OAFA 4DPHA 2W3AA 4XE6X 3FQVA 4H95A 3F0UX 1HFQA 4ELBA 3SR5X 2W9SA 1DR1A 4LAEX 4QHVA 4IXFX 4PSYA 1RX6A 1DHFA 3TQ9A 4XT7A 3QLWA 1DF7A 1RX2A 2L28A 1KMVA 3GHCA 1RA8A 3EELA 3NZDA 3JW5A 3SGYA 4QI9A 1IA4A 3IRNA 2CD2A 3FQOA 3GI2A 3E0BA 3VCOA 1RD7A 3FRBX 5JA3A 4IXGX 3SRRX 4LAHX 1DHJA 1LUDA 3TQBA 4KLXA 4PDJA 5HQZA 3CD2A 4IXED 1M78A 3KGYA 4XRBA 2ZZAA 1ZDRA 3DAUA 1VDRA 3OCHA 3TD8A 1AOEA 1RG7A 4EJ1A 2W3VA 1RA3A 2BLBA 3FS6A 3EX8A 4FHBA 3QL3A 3F0QX 1DRHA 4FGGA 3GHWA 2C2TA 5HVEA 3NTZA 1RA1A 1RE7A 4G3MA 3JSUA 5HF0X 3IROA 1U70A 3FRAX 1DR6A 3CLBA 3Q1HA 5FDAA 4XT4A 1VJ3A 1RX4A 5HSUA 4Q6AA 2W3MA 3KJRA 2HM9A 3NXOA 3QL0A 4ELHA 1RC4A 3FREX 3D80A 5HVBA 3HJ3A 4NX6A 3QYOA 3HBBA 3I3RA 1M7AA 3R33A 4DPDA 1DYHA 1CD2A 3NXRA 6DFRA 4GH8A 3JWKA 4DP3A 1J3KA 3NZ6X 3JW3A 1DR5A 3FRFX 3FQ0A 3CSEA 3EIGA 5ECCA 3GHVA 3JWCA 3FY9X 1QZFA 2CIGA 1DREA 4QLEA 4EIZA 4KM0A 4HA9A 3CL9A 2FZJA 1DG8A 3F0XX 1IA3A 3QLYA 1U72A 3I8AX 4KY8A 4KL9A 5E8QA 4KM2A 4PTHA 3EEMA 2LF1A 1IA1A 1MVSA 3SA2A 1LY3A 4H96A 4KBNA 3S9UA 1J3JA 3FL9A 1PD8A 4ELEA 1DYRA 3F0VX 4ELGA 5HUIA 4QJZD 3F0BX 1DR3A 4QLFA 1RB3A 4KJJA 3INVA 2G6VA 2DHFA 3ZPGA 4I1NA 3IRMA 4DFRA 2KGKA 1AI9A 4M6KA 5JG0X 1OHKA 3QLRA 1DRBA 2HQPA 4H98A 1KMSA 3SQYX 4ELFA 4G95A 4X5HA 3N0HA 2BLCA 2JYBA 3IA5A 1TDRA 3DATA 1RX1A 1PD9A 1U71A 4M6LA 2ITHA 2P4GA 3QG2A 1CZ3A 2W3WA 3DGAA 3K2HA 5HQYA 2W9HA 5U27A 4OSGA 3LG4A 2QK8A 1LY4A 3IA4A 4G8ZX 5CC9A 4RGCA 3SRQX 3SRWX 1SEJA 4OR7A 5DXVA 4KD7A 4P66A 3RO9A 4I13A 1BOZA 1RA2A 3FQFA 4KNEA 4M7VA 3NRRA 3S7AA 4HOEA 2FZIA 4KFJA 4M6JA 2INQA 1S3WA 2ANOA 4KJLA 3K74A 3L3RA 2HXVA 4H97A 4PTJA 3QLSA 1KLKA 1DHIA 4PSTA 3NZ9X 3SH2A 1DDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DYJ A;  1RX3 A;  4KAK A;  3UM6 A;  4XT8 A;  3IX9 A;  4Q0E A;  1RX7 A;  3NXX A;  5DFR A;  5EAJ A;  4CD2 A;  2W9T A;  3UM5 A;  1DDS A;  1HFR A;  3TQA A;  3SRU X;  3NZC X;  1DR7 A;  1S3Y A;  1YHO A;  1DYI A;  3FYV X;  2B3Z A;  5HSR A;  1DIS A;  1RX8 A;  4XT5 A;  1JOM A;  2OIP A;  3ZPC A;  2BL9 A;  5U26 A;  3NZA X;  2W9G A;  1DAJ A;  3K47 A;  1S3V A;  3JTW A;  2FZH A;  7DFR A;  5HT5 A;  4NX7 A;  1M79 A;  1DR2 A;  5ECX A;  1OHJ A;  3KY8 A;  4KEB A;  2BLA A;  3QLX A;  3JWF A;  3NXT A;  1E26 A;  3NU0 A;  1DG7 A;  2XW7 A;  1DLR A;  1HFP A;  4KY4 A;  2O7P A;  3SA1 A;  4X5F A;  3EEJ A;  3QFX A;  4P3Q A;  3M08 A;  4FGH A;  1J3I A;  4HA7 A;  4XT6 A;  2D5N A;  2ANQ A;  3ROA A;  3DL6 A;  1DLS A;  3D84 X;  3UM8 A;  2H2Q A;  4XEC X;  3SRS X;  5CCC A;  4X5I A;  1IA2 A;  4KJK A;  2GD9 A;  3DFR A;  1RX9 A;  3SAI A;  2OBC A;  4ECK A;  3RG9 A;  3QGT A;  4PSS A;  1RH3 A;  3F8Y A;  2DRC A;  3QYL A;  3F0S X;  4QLG A;  3FQC A;  3KFY A;  5HF2 X;  1BZF A;  1S3U A;  3KJS A;  4Q0D A;  3S3V A;  3GYF A;  1DIU A;  3QLZ A;  3FYW X;  8DFR A;  3F91 A;  3DRC A;  4P68 A;  5HI6 A;  1RA9 A;  4HOF A;  4LEK X;  1MVT A;  3JVX A;  3M09 A;  3NZB X;  5HPB A;  4EIG A;  1RF7 A;  3JWM A;  1AO8 A;  4M7U A;  1DRF A;  3FL8 A;  3DG8 A;  1JUV A;  1DRA A;  4HOG A;  2AZN A;  1D1G A;  3FRD X;  1DG5 A;  4LAG X;  4EIL A;  4DDR A;  3DL5 A;  2C2S A;  3F8Z A;  2D0K A;  4TU5 X;  3TQ8 A;  4QJC A;  3NXY A;  4P3R A;  3EEK A;  4Q67 A;  2W3B A;  1PDB A;  5HT4 A;  3FY8 X;  4M2X A;  4KYA A;  3K45 A;  4X5G A;  1JOL A;  1RB2 A;  1RX5 A;  3NXV A;  1DR4 A;  4X5J A;  3FQZ A;  3OAF A;  4DPH A;  2W3A A;  4XE6 X;  3FQV A;  4H95 A;  3F0U X;  1HFQ A;  4ELB A;  3SR5 X;  2W9S A;  1DR1 A;  4LAE X;  4QHV A;  4IXF X;  4PSY A;  1RX6 A;  1DHF A;  3TQ9 A;  4XT7 A;  3QLW A;  1DF7 A;  1RX2 A;  2L28 A;  1KMV A;  3GHC A;  1RA8 A;  3EEL A;  3NZD A;  3JW5 A;  3SGY A;  4QI9 A;  1IA4 A;  3IRN A;  2CD2 A;  3FQO A;  3GI2 A;  3E0B A;  3VCO A;  1RD7 A;  3FRB X;  5JA3 A;  4IXG X;  3SRR X;  4LAH X;  1DHJ A;  1LUD A;  3TQB A;  4KLX A;  4PDJ A;  5HQZ A;  3CD2 A;  4IXE D;  1M78 A;  3KGY A;  4XRB A;  2ZZA A;  1ZDR A;  3DAU A;  1VDR A;  3OCH A;  3TD8 A;  1AOE A;  1RG7 A;  4EJ1 A;  2W3V A;  1RA3 A;  2BLB A;  3FS6 A;  3EX8 A;  4FHB A;  3QL3 A;  3F0Q X;  1DRH A;  4FGG A;  3GHW A;  2C2T A;  5HVE A;  3NTZ A;  1RA1 A;  1RE7 A;  4G3M A;  3JSU A;  5HF0 X;  3IRO A;  1U70 A;  3FRA X;  1DR6 A;  3CLB A;  3Q1H A;  5FDA A;  4XT4 A;  1VJ3 A;  1RX4 A;  5HSU A;  4Q6A A;  2W3M A;  3KJR A;  2HM9 A;  3NXO A;  3QL0 A;  4ELH A;  1RC4 A;  3FRE X;  3D80 A;  5HVB A;  3HJ3 A;  4NX6 A;  3QYO A;  3HBB A;  3I3R A;  1M7A A;  3R33 A;  4DPD A;  1DYH A;  1CD2 A;  3NXR A;  6DFR A;  4GH8 A;  3JWK A;  4DP3 A;  1J3K A;  3NZ6 X;  3JW3 A;  1DR5 A;  3FRF X;  3FQ0 A;  3CSE A;  3EIG A;  5ECC A;  3GHV A;  3JWC A;  3FY9 X;  1QZF A;  2CIG A;  1DRE A;  4QLE A;  4EIZ A;  4KM0 A;  4HA9 A;  3CL9 A;  2FZJ A;  1DG8 A;  3F0X X;  1IA3 A;  3QLY A;  1U72 A;  3I8A X;  4KY8 A;  4KL9 A;  5E8Q A;  4KM2 A;  4PTH A;  3EEM A;  2LF1 A;  1IA1 A;  1MVS A;  3SA2 A;  1LY3 A;  4H96 A;  4KBN A;  3S9U A;  1J3J A;  3FL9 A;  1PD8 A;  4ELE A;  1DYR A;  3F0V X;  4ELG A;  5HUI A;  4QJZ D;  3F0B X;  1DR3 A;  4QLF A;  1RB3 A;  4KJJ A;  3INV A;  2G6V A;  2DHF A;  3ZPG A;  4I1N A;  3IRM A;  4DFR A;  2KGK A;  1AI9 A;  4M6K A;  5JG0 X;  1OHK A;  3QLR A;  1DRB A;  2HQP A;  4H98 A;  1KMS A;  3SQY X;  4ELF A;  4G95 A;  4X5H A;  3N0H A;  2BLC A;  2JYB A;  3IA5 A;  1TDR A;  3DAT A;  1RX1 A;  1PD9 A;  1U71 A;  4M6L A;  2ITH A;  2P4G A;  3QG2 A;  1CZ3 A;  2W3W A;  3DGA A;  3K2H A;  5HQY A;  2W9H A;  5U27 A;  4OSG A;  3LG4 A;  2QK8 A;  1LY4 A;  3IA4 A;  4G8Z X;  5CC9 A;  4RGC A;  3SRQ X;  3SRW X;  1SEJ A;  4OR7 A;  5DXV A;  4KD7 A;  4P66 A;  3RO9 A;  4I13 A;  1BOZ A;  1RA2 A;  3FQF A;  4KNE A;  4M7V A;  3NRR A;  3S7A A;  4HOE A;  2FZI A;  4KFJ A;  4M6J A;  2INQ A;  1S3W A;  2ANO A;  4KJL A;  3K74 A;  3L3R A;  2HXV A;  4H97 A;  4PTJ A;  3QLS A;  1KLK A;  1DHI A;  4PST A;  3NZ9 X;  3SH2 A;  1DDR A; 
#chains in the Genus database with same CATH topology
 1DYJ A;  1RX3 A;  4KAK A;  3UM6 A;  4XT8 A;  3IX9 A;  4Q0E A;  1RX7 A;  3NXX A;  5DFR A;  5EAJ A;  4CD2 A;  2W9T A;  3UM5 A;  1DDS A;  1HFR A;  3TQA A;  3SRU X;  3NZC X;  1DR7 A;  1S3Y A;  1YHO A;  1DYI A;  3FYV X;  2B3Z A;  5HSR A;  1DIS A;  1RX8 A;  4XT5 A;  1JOM A;  2OIP A;  3ZPC A;  2BL9 A;  5U26 A;  3NZA X;  2W9G A;  1DAJ A;  3K47 A;  1S3V A;  3JTW A;  2FZH A;  7DFR A;  5HT5 A;  4NX7 A;  1M79 A;  1DR2 A;  5ECX A;  1OHJ A;  3KY8 A;  4KEB A;  2BLA A;  3QLX A;  3JWF A;  3NXT A;  1E26 A;  3NU0 A;  1DG7 A;  2XW7 A;  1DLR A;  1HFP A;  4KY4 A;  2O7P A;  3SA1 A;  4X5F A;  3EEJ A;  3QFX A;  4P3Q A;  3M08 A;  4FGH A;  1J3I A;  4HA7 A;  4XT6 A;  2D5N A;  2ANQ A;  3ROA A;  3DL6 A;  1DLS A;  3D84 X;  3UM8 A;  2H2Q A;  4XEC X;  3SRS X;  5CCC A;  4X5I A;  1IA2 A;  4KJK A;  2GD9 A;  3DFR A;  1RX9 A;  3SAI A;  2OBC A;  4ECK A;  3RG9 A;  3QGT A;  4PSS A;  1RH3 A;  3F8Y A;  2DRC A;  3QYL A;  3F0S X;  4QLG A;  3FQC A;  3KFY A;  5HF2 X;  1BZF A;  1S3U A;  3KJS A;  4Q0D A;  3S3V A;  3GYF A;  1DIU A;  3QLZ A;  3FYW X;  8DFR A;  3F91 A;  3DRC A;  4P68 A;  5HI6 A;  1RA9 A;  4HOF A;  4LEK X;  1MVT A;  3JVX A;  3M09 A;  3NZB X;  5HPB A;  4EIG A;  1RF7 A;  3JWM A;  1AO8 A;  4M7U A;  1DRF A;  3FL8 A;  3DG8 A;  1JUV A;  1DRA A;  4HOG A;  2AZN A;  1D1G A;  3FRD X;  1DG5 A;  4LAG X;  4EIL A;  4DDR A;  3DL5 A;  2C2S A;  3F8Z A;  2D0K A;  4TU5 X;  3TQ8 A;  4QJC A;  3NXY A;  4P3R A;  3EEK A;  4Q67 A;  2W3B A;  1PDB A;  5HT4 A;  3FY8 X;  4M2X A;  4KYA A;  3K45 A;  4X5G A;  1JOL A;  1RB2 A;  1RX5 A;  3NXV A;  1DR4 A;  4X5J A;  3FQZ A;  3OAF A;  4DPH A;  2W3A A;  4XE6 X;  3FQV A;  4H95 A;  3F0U X;  1HFQ A;  4ELB A;  3SR5 X;  2W9S A;  1DR1 A;  4LAE X;  4QHV A;  4IXF X;  4PSY A;  1RX6 A;  1DHF A;  3TQ9 A;  4XT7 A;  3QLW A;  1DF7 A;  1RX2 A;  2L28 A;  1KMV A;  3GHC A;  1RA8 A;  3EEL A;  3NZD A;  3JW5 A;  3SGY A;  4QI9 A;  1IA4 A;  3IRN A;  2CD2 A;  3FQO A;  3GI2 A;  3E0B A;  3VCO A;  1RD7 A;  3FRB X;  5JA3 A;  4IXG X;  3SRR X;  4LAH X;  1DHJ A;  1LUD A;  3TQB A;  4KLX A;  4PDJ A;  5HQZ A;  3CD2 A;  4IXE D;  1M78 A;  3KGY A;  4XRB A;  2ZZA A;  1ZDR A;  3DAU A;  1VDR A;  3OCH A;  3TD8 A;  1AOE A;  1RG7 A;  4EJ1 A;  2W3V A;  1RA3 A;  2BLB A;  3FS6 A;  3EX8 A;  4FHB A;  3QL3 A;  3F0Q X;  1DRH A;  4FGG A;  3GHW A;  2C2T A;  5HVE A;  3NTZ A;  1RA1 A;  1RE7 A;  4G3M A;  3JSU A;  5HF0 X;  3IRO A;  1U70 A;  3FRA X;  1DR6 A;  3CLB A;  3Q1H A;  5FDA A;  4XT4 A;  1VJ3 A;  1RX4 A;  5HSU A;  4Q6A A;  2W3M A;  3KJR A;  2HM9 A;  3NXO A;  3QL0 A;  4ELH A;  1RC4 A;  3FRE X;  3D80 A;  5HVB A;  3HJ3 A;  4NX6 A;  3QYO A;  3HBB A;  3I3R A;  1M7A A;  3R33 A;  4DPD A;  1DYH A;  1CD2 A;  3NXR A;  6DFR A;  4GH8 A;  3JWK A;  4DP3 A;  1J3K A;  3NZ6 X;  3JW3 A;  1DR5 A;  3FRF X;  3FQ0 A;  3CSE A;  3EIG A;  5ECC A;  3GHV A;  3JWC A;  3FY9 X;  1QZF A;  2CIG A;  1DRE A;  4QLE A;  4EIZ A;  4KM0 A;  4HA9 A;  3CL9 A;  2FZJ A;  1DG8 A;  3F0X X;  1IA3 A;  3QLY A;  1U72 A;  3I8A X;  4KY8 A;  4KL9 A;  5E8Q A;  4KM2 A;  4PTH A;  3EEM A;  2LF1 A;  1IA1 A;  1MVS A;  3SA2 A;  1LY3 A;  4H96 A;  4KBN A;  3S9U A;  1J3J A;  3FL9 A;  1PD8 A;  4ELE A;  1DYR A;  3F0V X;  4ELG A;  5HUI A;  4QJZ D;  3F0B X;  1DR3 A;  4QLF A;  1RB3 A;  4KJJ A;  3INV A;  2G6V A;  2DHF A;  3ZPG A;  4I1N A;  3IRM A;  4DFR A;  2KGK A;  1AI9 A;  4M6K A;  5JG0 X;  1OHK A;  3QLR A;  1DRB A;  2HQP A;  4H98 A;  1KMS A;  3SQY X;  4ELF A;  4G95 A;  4X5H A;  3N0H A;  2BLC A;  2JYB A;  3IA5 A;  1TDR A;  3DAT A;  1RX1 A;  1PD9 A;  1U71 A;  4M6L A;  2ITH A;  2P4G A;  3QG2 A;  1CZ3 A;  2W3W A;  3DGA A;  3K2H A;  5HQY A;  2W9H A;  5U27 A;  4OSG A;  3LG4 A;  2QK8 A;  1LY4 A;  3IA4 A;  4G8Z X;  5CC9 A;  4RGC A;  3SRQ X;  3SRW X;  1SEJ A;  4OR7 A;  5DXV A;  4KD7 A;  4P66 A;  3RO9 A;  4I13 A;  1BOZ A;  1RA2 A;  3FQF A;  4KNE A;  4M7V A;  3NRR A;  3S7A A;  4HOE A;  2FZI A;  4KFJ A;  4M6J A;  2INQ A;  1S3W A;  2ANO A;  4KJL A;  3K74 A;  3L3R A;  2HXV A;  4H97 A;  4PTJ A;  3QLS A;  1KLK A;  1DHI A;  4PST A;  3NZ9 X;  3SH2 A;  1DDR A; 
#chains in the Genus database with same CATH homology
 1DYJ A;  1RX3 A;  4KAK A;  3UM6 A;  4XT8 A;  3IX9 A;  4Q0E A;  1RX7 A;  3NXX A;  5DFR A;  5EAJ A;  4CD2 A;  2W9T A;  3UM5 A;  1DDS A;  1HFR A;  3TQA A;  3SRU X;  3NZC X;  1DR7 A;  1S3Y A;  1YHO A;  1DYI A;  3FYV X;  2B3Z A;  5HSR A;  1DIS A;  1RX8 A;  4XT5 A;  1JOM A;  2OIP A;  3ZPC A;  2BL9 A;  5U26 A;  3NZA X;  2W9G A;  1DAJ A;  3K47 A;  1S3V A;  3JTW A;  2FZH A;  7DFR A;  5HT5 A;  4NX7 A;  1M79 A;  1DR2 A;  5ECX A;  1OHJ A;  3KY8 A;  4KEB A;  2BLA A;  3QLX A;  3JWF A;  3NXT A;  1E26 A;  3NU0 A;  1DG7 A;  2XW7 A;  1DLR A;  1HFP A;  4KY4 A;  2O7P A;  3SA1 A;  4X5F A;  3EEJ A;  3QFX A;  4P3Q A;  3M08 A;  4FGH A;  1J3I A;  4HA7 A;  4XT6 A;  2D5N A;  2ANQ A;  3ROA A;  3DL6 A;  1DLS A;  3D84 X;  3UM8 A;  2H2Q A;  4XEC X;  3SRS X;  5CCC A;  4X5I A;  1IA2 A;  4KJK A;  2GD9 A;  3DFR A;  1RX9 A;  3SAI A;  2OBC A;  4ECK A;  3RG9 A;  3QGT A;  4PSS A;  1RH3 A;  3F8Y A;  2DRC A;  3QYL A;  3F0S X;  4QLG A;  3FQC A;  3KFY A;  5HF2 X;  1BZF A;  1S3U A;  3KJS A;  4Q0D A;  3S3V A;  3GYF A;  1DIU A;  3QLZ A;  3FYW X;  8DFR A;  3F91 A;  3DRC A;  4P68 A;  5HI6 A;  1RA9 A;  4HOF A;  4LEK X;  1MVT A;  3JVX A;  3M09 A;  3NZB X;  5HPB A;  4EIG A;  1RF7 A;  3JWM A;  1AO8 A;  4M7U A;  1DRF A;  3FL8 A;  3DG8 A;  1JUV A;  1DRA A;  4HOG A;  2AZN A;  1D1G A;  3FRD X;  1DG5 A;  4LAG X;  4EIL A;  4DDR A;  3DL5 A;  2C2S A;  3F8Z A;  2D0K A;  4TU5 X;  3TQ8 A;  4QJC A;  3NXY A;  4P3R A;  3EEK A;  4Q67 A;  2W3B A;  1PDB A;  5HT4 A;  3FY8 X;  4M2X A;  4KYA A;  3K45 A;  4X5G A;  1JOL A;  1RB2 A;  1RX5 A;  3NXV A;  1DR4 A;  4X5J A;  3FQZ A;  3OAF A;  4DPH A;  2W3A A;  4XE6 X;  3FQV A;  4H95 A;  3F0U X;  1HFQ A;  4ELB A;  3SR5 X;  2W9S A;  1DR1 A;  4LAE X;  4QHV A;  4IXF X;  4PSY A;  1RX6 A;  1DHF A;  3TQ9 A;  4XT7 A;  3QLW A;  1DF7 A;  1RX2 A;  2L28 A;  1KMV A;  3GHC A;  1RA8 A;  3EEL A;  3NZD A;  3JW5 A;  3SGY A;  4QI9 A;  1IA4 A;  3IRN A;  2CD2 A;  3FQO A;  3GI2 A;  3E0B A;  3VCO A;  1RD7 A;  3FRB X;  5JA3 A;  4IXG X;  3SRR X;  4LAH X;  1DHJ A;  1LUD A;  3TQB A;  4KLX A;  4PDJ A;  5HQZ A;  3CD2 A;  4IXE D;  1M78 A;  3KGY A;  4XRB A;  2ZZA A;  1ZDR A;  3DAU A;  1VDR A;  3OCH A;  3TD8 A;  1AOE A;  1RG7 A;  4EJ1 A;  2W3V A;  1RA3 A;  2BLB A;  3FS6 A;  3EX8 A;  4FHB A;  3QL3 A;  3F0Q X;  1DRH A;  4FGG A;  3GHW A;  2C2T A;  5HVE A;  3NTZ A;  1RA1 A;  1RE7 A;  4G3M A;  3JSU A;  5HF0 X;  3IRO A;  1U70 A;  3FRA X;  1DR6 A;  3CLB A;  3Q1H A;  5FDA A;  4XT4 A;  1VJ3 A;  1RX4 A;  5HSU A;  4Q6A A;  2W3M A;  3KJR A;  2HM9 A;  3NXO A;  3QL0 A;  4ELH A;  1RC4 A;  3FRE X;  3D80 A;  5HVB A;  3HJ3 A;  4NX6 A;  3QYO A;  3HBB A;  3I3R A;  1M7A A;  3R33 A;  4DPD A;  1DYH A;  1CD2 A;  3NXR A;  6DFR A;  4GH8 A;  3JWK A;  4DP3 A;  1J3K A;  3NZ6 X;  3JW3 A;  1DR5 A;  3FRF X;  3FQ0 A;  3CSE A;  3EIG A;  5ECC A;  3GHV A;  3JWC A;  3FY9 X;  1QZF A;  2CIG A;  1DRE A;  4QLE A;  4EIZ A;  4KM0 A;  4HA9 A;  3CL9 A;  2FZJ A;  1DG8 A;  3F0X X;  1IA3 A;  3QLY A;  1U72 A;  3I8A X;  4KY8 A;  4KL9 A;  5E8Q A;  4KM2 A;  4PTH A;  3EEM A;  2LF1 A;  1IA1 A;  1MVS A;  3SA2 A;  1LY3 A;  4H96 A;  4KBN A;  3S9U A;  1J3J A;  3FL9 A;  1PD8 A;  4ELE A;  1DYR A;  3F0V X;  4ELG A;  5HUI A;  4QJZ D;  3F0B X;  1DR3 A;  4QLF A;  1RB3 A;  4KJJ A;  3INV A;  2G6V A;  2DHF A;  3ZPG A;  4I1N A;  3IRM A;  4DFR A;  2KGK A;  1AI9 A;  4M6K A;  5JG0 X;  1OHK A;  3QLR A;  1DRB A;  2HQP A;  4H98 A;  1KMS A;  3SQY X;  4ELF A;  4G95 A;  4X5H A;  3N0H A;  2BLC A;  2JYB A;  3IA5 A;  1TDR A;  3DAT A;  1RX1 A;  1PD9 A;  1U71 A;  4M6L A;  2ITH A;  2P4G A;  3QG2 A;  1CZ3 A;  2W3W A;  3DGA A;  3K2H A;  5HQY A;  2W9H A;  5U27 A;  4OSG A;  3LG4 A;  2QK8 A;  1LY4 A;  3IA4 A;  4G8Z X;  5CC9 A;  4RGC A;  3SRQ X;  3SRW X;  1SEJ A;  4OR7 A;  5DXV A;  4KD7 A;  4P66 A;  3RO9 A;  4I13 A;  1BOZ A;  1RA2 A;  3FQF A;  4KNE A;  4M7V A;  3NRR A;  3S7A A;  4HOE A;  2FZI A;  4KFJ A;  4M6J A;  2INQ A;  1S3W A;  2ANO A;  4KJL A;  3K74 A;  3L3R A;  2HXV A;  4H97 A;  4PTJ A;  3QLS A;  1KLK A;  1DHI A;  4PST A;  3NZ9 X;  3SH2 A;  1DDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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