1RX4A

Dihydrofolate reductase (e.c.1.5.1.3) complexed with 5,10-dideazatetrahydrofolate and 2'-monophosphoadenosine 5'-diphosphoribose
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 45
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rx4A00
1KMSA 3FRFX 5FDAA 3SRQX 3GYFA 3KGYA 3CD2A 1RF7A 4KM2A 3UM6A 3TQ8A 1DR1A 3QGTA 1JOLA 3IRNA 6DFRA 4XRBA 3EIGA 4X5FA 3SH2A 1OHJA 4KD7A 3FQ0A 3F8YA 1DHFA 3JW5A 3SRSX 3QL3A 1RD7A 1DR6A 1OHKA 1PD8A 4I1NA 1ZDRA 2KGKA 1KLKA 3QYLA 3ZPCA 1RE7A 3CSEA 4PSTA 4Q0EA 3EEKA 2AZNA 4M6LA 4HA9A 5E8QA 3FY8X 3QFXA 4IXGX 3TQBA 3QLRA 2HXVA 1VDRA 2G6VA 3DFRA 1AOEA 2ANQA 3NZ6X 1JOMA 1IA3A 3ZPGA 4KNEA 2C2SA 1RX1A 4P3QA 4KJJA 4IXFX 1AO8A 1RX8A 2FZHA 4G95A 2ITHA 2BLBA 2D0KA 3FRBX 3F0XX 1DYJA 1DR2A 2INQA 3QYOA 4ELBA 3NZ9X 4RGCA 5HI6A 3S9UA 5EAJA 5U26A 4KFJA 4DFRA 1IA4A 4XE6X 5HVBA 2BL9A 4Q0DA 3KJSA 3NXOA 3EEJA 1U70A 2BLCA 4HA7A 1DISA 3M08A 4ECKA 3TQ9A 1J3KA 3FL8A 4PDJA 2CIGA 4EJ1A 4EIGA 3GHCA 2W3VA 4PTJA 2W9TA 4HOGA 1DR5A 1RX9A 2JYBA 1M79A 4P3RA 1QZFA 3FQZA 3JWKA 4LEKX 3JWMA 4PSSA 4P66A 3S3VA 1AI9A 3JSUA 4FGHA 2B3ZA 1RX6A 3CLBA 3INVA 2W3AA 3NZAX 3SRRX 3L3RA 4XECX 1DAJA 4XT7A 1RA3A 4I13A 1DR3A 2W9SA 3JW3A 1DYRA 2LF1A 4KL9A 4M7UA 3FRAX 1RC4A 1DG8A 4X5GA 1RX5A 2OIPA 4KEBA 1BZFA 5HSRA 4NX6A 4X5JA 1LUDA 5HQYA 5HF2X 4M6KA 3NTZA 5ECXA 3FQOA 3OAFA 1J3JA 3DL5A 4G8ZX 1RB3A 1PD9A 1S3WA 3DG8A 4LAEX 2H2QA 4HOEA 3SGYA 1DRBA 3E0BA 1DRAA 4XT5A 1DREA 1JUVA 3F0VX 4KYAA 4LAHX 2W3MA 4ELEA 3EX8A 4QLFA 1DYHA 3NZCX 3QLXA 3FY9X 1RA1A 4GH8A 3GI2A 3HBBA 1YHOA 3F8ZA 4XT6A 4M6JA 5HVEA 4DPDA 4H98A 1RA9A 4H96A 4PSYA 1DYIA 3NRRA 3RG9A 2FZIA 3FQFA 1PDBA 3SA1A 3NXTA 3F0UX 2D5NA 3EELA 3SR5X 3IRMA 4OSGA 1DRHA 4IXED 3HJ3A 4KAKA 4KY4A 4FGGA 3NXYA 1DDSA 3VCOA 1RX7A 4XT4A 2OBCA 4PTHA 4QJCA 1IA1A 1DLRA 3FS6A 5HT4A 3K45A 3EEMA 1S3YA 3FREX 4EIZA 4QI9A 3F91A 3SRUX 1DF7A 1RA2A 2P4GA 1SEJA 3SAIA 3I8AX 1DHIA 3QG2A 4ELHA 3DAUA 4P68A 1LY4A 3KFYA 4KY8A 1IA2A 2QK8A 3KY8A 4XT8A 1S3UA 3FYWX 1DR7A 4QHVA 3IROA 1M7AA 3QLYA 1DHJA 2GD9A 3FQCA 4H97A 5CC9A 3JWFA 1U71A 1J3IA 3FL9A 4QJZD 1DLSA 2W3BA 3I3RA 5ECCA 1DR4A 5CCCA 1HFRA 5HSUA 1CZ3A 1KMVA 3F0SX 3JTWA 1DG5A 1RH3A 3QL0A 3M09A 1DG7A 4LAGX 4H95A 3IA5A 3NXXA 2L28A 5HQZA 3QLWA 1VJ3A 1RG7A 1RX4A 5DXVA 3NU0A 4Q6AA 4KLXA 1RX3A 3UM8A 1BOZA 3D84X 2ANOA 7DFRA 2BLAA 1MVTA 3FRDX 2FZJA 2XW7A 3K47A 3TD8A 3OCHA 3JWCA 1TDRA 3TQAA 4TU5X 4X5HA 2CD2A 4KJLA 3GHWA 1HFPA 4NX7A 1M78A 5HUIA 1HFQA 2DHFA 4DP3A 4CD2A 2HQPA 1D1GA 1RA8A 3F0BX 4KM0A 3SA2A 4QLGA 3D80A 2C2TA 2DRCA 1S3VA 2ZZAA 5HT5A 4ELGA 4HOFA 3N0HA 5HF0X 3SQYX 4FHBA 4KJKA 1MVSA 3ROAA 4EILA 3NXRA 3RO9A 3F0QX 2O7PA 1RX2A 4QLEA 3R33A 3FQVA 1RB2A 4Q67A 3Q1HA 3UM5A 3GHVA 5JG0X 3DL6A 1DRFA 4ELFA 3IA4A 4DDRA 3KJRA 2HM9A 4DPHA 3K74A 5HPBA 1U72A 3DRCA 3IX9A 2W9GA 3NXVA 1E26A 4KBNA 2W3WA 1LY3A 3DGAA 4G3MA 3LG4A 3CL9A 3DATA 3FYVX 3NZDA 8DFRA 4OR7A 3NZBX 1CD2A 4M7VA 5DFRA 5JA3A 3SRWX 1DDRA 3QLZA 2W9HA 3S7AA 3K2HA 1DIUA 3QLSA 3JVXA 5U27A 4M2XA 4X5IA
chains in the Genus database with same CATH superfamily
1KMSA 3FRFX 5FDAA 3SRQX 3GYFA 3KGYA 3CD2A 1RF7A 4KM2A 3UM6A 3TQ8A 1DR1A 3QGTA 1JOLA 3IRNA 6DFRA 4XRBA 3EIGA 4X5FA 3SH2A 1OHJA 4KD7A 3FQ0A 3F8YA 1DHFA 3JW5A 3SRSX 3QL3A 1RD7A 1DR6A 1OHKA 1PD8A 4I1NA 1ZDRA 2KGKA 1KLKA 3QYLA 3ZPCA 1RE7A 3CSEA 4PSTA 4Q0EA 3EEKA 2AZNA 4M6LA 4HA9A 5E8QA 3FY8X 3QFXA 4IXGX 3TQBA 3QLRA 2HXVA 1VDRA 2G6VA 3DFRA 1AOEA 2ANQA 3NZ6X 1JOMA 1IA3A 3ZPGA 4KNEA 2C2SA 1RX1A 4P3QA 4KJJA 4IXFX 1AO8A 1RX8A 2FZHA 4G95A 2ITHA 2BLBA 2D0KA 3FRBX 3F0XX 1DYJA 1DR2A 2INQA 3QYOA 4ELBA 3NZ9X 4RGCA 5HI6A 3S9UA 5EAJA 5U26A 4KFJA 4DFRA 1IA4A 4XE6X 5HVBA 2BL9A 4Q0DA 3KJSA 3NXOA 3EEJA 1U70A 2BLCA 4HA7A 1DISA 3M08A 4ECKA 3TQ9A 1J3KA 3FL8A 4PDJA 2CIGA 4EJ1A 4EIGA 3GHCA 2W3VA 4PTJA 2W9TA 4HOGA 1DR5A 1RX9A 2JYBA 1M79A 4P3RA 1QZFA 3FQZA 3JWKA 4LEKX 3JWMA 4PSSA 4P66A 3S3VA 1AI9A 3JSUA 4FGHA 2B3ZA 1RX6A 3CLBA 3INVA 2W3AA 3NZAX 3SRRX 3L3RA 4XECX 1DAJA 4XT7A 1RA3A 4I13A 1DR3A 2W9SA 3JW3A 1DYRA 2LF1A 4KL9A 4M7UA 3FRAX 1RC4A 1DG8A 4X5GA 1RX5A 2OIPA 4KEBA 1BZFA 5HSRA 4NX6A 4X5JA 1LUDA 5HQYA 5HF2X 4M6KA 3NTZA 5ECXA 3FQOA 3OAFA 1J3JA 3DL5A 4G8ZX 1RB3A 1PD9A 1S3WA 3DG8A 4LAEX 2H2QA 4HOEA 3SGYA 1DRBA 3E0BA 1DRAA 4XT5A 1DREA 1JUVA 3F0VX 4KYAA 4LAHX 2W3MA 4ELEA 3EX8A 4QLFA 1DYHA 3NZCX 3QLXA 3FY9X 1RA1A 4GH8A 3GI2A 3HBBA 1YHOA 3F8ZA 4XT6A 4M6JA 5HVEA 4DPDA 4H98A 1RA9A 4H96A 4PSYA 1DYIA 3NRRA 3RG9A 2FZIA 3FQFA 1PDBA 3SA1A 3NXTA 3F0UX 2D5NA 3EELA 3SR5X 3IRMA 4OSGA 1DRHA 4IXED 3HJ3A 4KAKA 4KY4A 4FGGA 3NXYA 1DDSA 3VCOA 1RX7A 4XT4A 2OBCA 4PTHA 4QJCA 1IA1A 1DLRA 3FS6A 5HT4A 3K45A 3EEMA 1S3YA 3FREX 4EIZA 4QI9A 3F91A 3SRUX 1DF7A 1RA2A 2P4GA 1SEJA 3SAIA 3I8AX 1DHIA 3QG2A 4ELHA 3DAUA 4P68A 1LY4A 3KFYA 4KY8A 1IA2A 2QK8A 3KY8A 4XT8A 1S3UA 3FYWX 1DR7A 4QHVA 3IROA 1M7AA 3QLYA 1DHJA 2GD9A 3FQCA 4H97A 5CC9A 3JWFA 1U71A 1J3IA 3FL9A 4QJZD 1DLSA 2W3BA 3I3RA 5ECCA 1DR4A 5CCCA 1HFRA 5HSUA 1CZ3A 1KMVA 3F0SX 3JTWA 1DG5A 1RH3A 3QL0A 3M09A 1DG7A 4LAGX 4H95A 3IA5A 3NXXA 2L28A 5HQZA 3QLWA 1VJ3A 1RG7A 1RX4A 5DXVA 3NU0A 4Q6AA 4KLXA 1RX3A 3UM8A 1BOZA 3D84X 2ANOA 7DFRA 2BLAA 1MVTA 3FRDX 2FZJA 2XW7A 3K47A 3TD8A 3OCHA 3JWCA 1TDRA 3TQAA 4TU5X 4X5HA 2CD2A 4KJLA 3GHWA 1HFPA 4NX7A 1M78A 5HUIA 1HFQA 2DHFA 4DP3A 4CD2A 2HQPA 1D1GA 1RA8A 3F0BX 4KM0A 3SA2A 4QLGA 3D80A 2C2TA 2DRCA 1S3VA 2ZZAA 5HT5A 4ELGA 4HOFA 3N0HA 5HF0X 3SQYX 4FHBA 4KJKA 1MVSA 3ROAA 4EILA 3NXRA 3RO9A 3F0QX 2O7PA 1RX2A 4QLEA 3R33A 3FQVA 1RB2A 4Q67A 3Q1HA 3UM5A 3GHVA 5JG0X 3DL6A 1DRFA 4ELFA 3IA4A 4DDRA 3KJRA 2HM9A 4DPHA 3K74A 5HPBA 1U72A 3DRCA 3IX9A 2W9GA 3NXVA 1E26A 4KBNA 2W3WA 1LY3A 3DGAA 4G3MA 3LG4A 3CL9A 3DATA 3FYVX 3NZDA 8DFRA 4OR7A 3NZBX 1CD2A 4M7VA 5DFRA 5JA3A 3SRWX 1DDRA 3QLZA 2W9HA 3S7AA 3K2HA 1DIUA 3QLSA 3JVXA 5U27A 4M2XA 4X5IA
chains in the Genus database with same CATH topology
1KMSA 3FRFX 5FDAA 3SRQX 3GYFA 3KGYA 3CD2A 1RF7A 4KM2A 3UM6A 3TQ8A 1DR1A 3QGTA 1JOLA 3IRNA 6DFRA 4XRBA 3EIGA 4X5FA 3SH2A 1OHJA 4KD7A 3FQ0A 3F8YA 1DHFA 3JW5A 3SRSX 3QL3A 1RD7A 1DR6A 1OHKA 1PD8A 4I1NA 1ZDRA 2KGKA 1KLKA 3QYLA 3ZPCA 1RE7A 3CSEA 4PSTA 4Q0EA 3EEKA 2AZNA 4M6LA 4HA9A 5E8QA 3FY8X 3QFXA 4IXGX 3TQBA 3QLRA 2HXVA 1VDRA 2G6VA 3DFRA 1AOEA 2ANQA 3NZ6X 1JOMA 1IA3A 3ZPGA 4KNEA 2C2SA 1RX1A 4P3QA 4KJJA 4IXFX 1AO8A 1RX8A 2FZHA 4G95A 2ITHA 2BLBA 2D0KA 3FRBX 3F0XX 1DYJA 1DR2A 2INQA 3QYOA 4ELBA 3NZ9X 4RGCA 5HI6A 3S9UA 5EAJA 5U26A 4KFJA 4DFRA 1IA4A 4XE6X 5HVBA 2BL9A 4Q0DA 3KJSA 3NXOA 3EEJA 1U70A 2BLCA 4HA7A 1DISA 3M08A 4ECKA 3TQ9A 1J3KA 3FL8A 4PDJA 2CIGA 4EJ1A 4EIGA 3GHCA 2W3VA 4PTJA 2W9TA 4HOGA 1DR5A 1RX9A 2JYBA 1M79A 4P3RA 1QZFA 3FQZA 3JWKA 4LEKX 3JWMA 4PSSA 4P66A 3S3VA 1AI9A 3JSUA 4FGHA 2B3ZA 1RX6A 3CLBA 3INVA 2W3AA 3NZAX 3SRRX 3L3RA 4XECX 1DAJA 4XT7A 1RA3A 4I13A 1DR3A 2W9SA 3JW3A 1DYRA 2LF1A 4KL9A 4M7UA 3FRAX 1RC4A 1DG8A 4X5GA 1RX5A 2OIPA 4KEBA 1BZFA 5HSRA 4NX6A 4X5JA 1LUDA 5HQYA 5HF2X 4M6KA 3NTZA 5ECXA 3FQOA 3OAFA 1J3JA 3DL5A 4G8ZX 1RB3A 1PD9A 1S3WA 3DG8A 4LAEX 2H2QA 4HOEA 3SGYA 1DRBA 3E0BA 1DRAA 4XT5A 1DREA 1JUVA 3F0VX 4KYAA 4LAHX 2W3MA 4ELEA 3EX8A 4QLFA 1DYHA 3NZCX 3QLXA 3FY9X 1RA1A 4GH8A 3GI2A 3HBBA 1YHOA 3F8ZA 4XT6A 4M6JA 5HVEA 4DPDA 4H98A 1RA9A 4H96A 4PSYA 1DYIA 3NRRA 3RG9A 2FZIA 3FQFA 1PDBA 3SA1A 3NXTA 3F0UX 2D5NA 3EELA 3SR5X 3IRMA 4OSGA 1DRHA 4IXED 3HJ3A 4KAKA 4KY4A 4FGGA 3NXYA 1DDSA 3VCOA 1RX7A 4XT4A 2OBCA 4PTHA 4QJCA 1IA1A 1DLRA 3FS6A 5HT4A 3K45A 3EEMA 1S3YA 3FREX 4EIZA 4QI9A 3F91A 3SRUX 1DF7A 1RA2A 2P4GA 1SEJA 3SAIA 3I8AX 1DHIA 3QG2A 4ELHA 3DAUA 4P68A 1LY4A 3KFYA 4KY8A 1IA2A 2QK8A 3KY8A 4XT8A 1S3UA 3FYWX 1DR7A 4QHVA 3IROA 1M7AA 3QLYA 1DHJA 2GD9A 3FQCA 4H97A 5CC9A 3JWFA 1U71A 1J3IA 3FL9A 4QJZD 1DLSA 2W3BA 3I3RA 5ECCA 1DR4A 5CCCA 1HFRA 5HSUA 1CZ3A 1KMVA 3F0SX 3JTWA 1DG5A 1RH3A 3QL0A 3M09A 1DG7A 4LAGX 4H95A 3IA5A 3NXXA 2L28A 5HQZA 3QLWA 1VJ3A 1RG7A 1RX4A 5DXVA 3NU0A 4Q6AA 4KLXA 1RX3A 3UM8A 1BOZA 3D84X 2ANOA 7DFRA 2BLAA 1MVTA 3FRDX 2FZJA 2XW7A 3K47A 3TD8A 3OCHA 3JWCA 1TDRA 3TQAA 4TU5X 4X5HA 2CD2A 4KJLA 3GHWA 1HFPA 4NX7A 1M78A 5HUIA 1HFQA 2DHFA 4DP3A 4CD2A 2HQPA 1D1GA 1RA8A 3F0BX 4KM0A 3SA2A 4QLGA 3D80A 2C2TA 2DRCA 1S3VA 2ZZAA 5HT5A 4ELGA 4HOFA 3N0HA 5HF0X 3SQYX 4FHBA 4KJKA 1MVSA 3ROAA 4EILA 3NXRA 3RO9A 3F0QX 2O7PA 1RX2A 4QLEA 3R33A 3FQVA 1RB2A 4Q67A 3Q1HA 3UM5A 3GHVA 5JG0X 3DL6A 1DRFA 4ELFA 3IA4A 4DDRA 3KJRA 2HM9A 4DPHA 3K74A 5HPBA 1U72A 3DRCA 3IX9A 2W9GA 3NXVA 1E26A 4KBNA 2W3WA 1LY3A 3DGAA 4G3MA 3LG4A 3CL9A 3DATA 3FYVX 3NZDA 8DFRA 4OR7A 3NZBX 1CD2A 4M7VA 5DFRA 5JA3A 3SRWX 1DDRA 3QLZA 2W9HA 3S7AA 3K2HA 1DIUA 3QLSA 3JVXA 5U27A 4M2XA 4X5IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KMS A;  3FRF X;  5FDA A;  3SRQ X;  3GYF A;  3KGY A;  3CD2 A;  1RF7 A;  4KM2 A;  3UM6 A;  3TQ8 A;  1DR1 A;  3QGT A;  1JOL A;  3IRN A;  6DFR A;  4XRB A;  3EIG A;  4X5F A;  3SH2 A;  1OHJ A;  4KD7 A;  3FQ0 A;  3F8Y A;  1DHF A;  3JW5 A;  3SRS X;  3QL3 A;  1RD7 A;  1DR6 A;  1OHK A;  1PD8 A;  4I1N A;  1ZDR A;  2KGK A;  1KLK A;  3QYL A;  3ZPC A;  1RE7 A;  3CSE A;  4PST A;  4Q0E A;  3EEK A;  2AZN A;  4M6L A;  4HA9 A;  5E8Q A;  3FY8 X;  3QFX A;  4IXG X;  3TQB A;  3QLR A;  2HXV A;  1VDR A;  2G6V A;  3DFR A;  1AOE A;  2ANQ A;  3NZ6 X;  1JOM A;  1IA3 A;  3ZPG A;  4KNE A;  2C2S A;  1RX1 A;  4P3Q A;  4KJJ A;  4IXF X;  1AO8 A;  1RX8 A;  2FZH A;  4G95 A;  2ITH A;  2BLB A;  2D0K A;  3FRB X;  3F0X X;  1DYJ A;  1DR2 A;  2INQ A;  3QYO A;  4ELB A;  3NZ9 X;  4RGC A;  5HI6 A;  3S9U A;  5EAJ A;  5U26 A;  4KFJ A;  4DFR A;  1IA4 A;  4XE6 X;  5HVB A;  2BL9 A;  4Q0D A;  3KJS A;  3NXO A;  3EEJ A;  1U70 A;  2BLC A;  4HA7 A;  1DIS A;  3M08 A;  4ECK A;  3TQ9 A;  1J3K A;  3FL8 A;  4PDJ A;  2CIG A;  4EJ1 A;  4EIG A;  3GHC A;  2W3V A;  4PTJ A;  2W9T A;  4HOG A;  1DR5 A;  1RX9 A;  2JYB A;  1M79 A;  4P3R A;  1QZF A;  3FQZ A;  3JWK A;  4LEK X;  3JWM A;  4PSS A;  4P66 A;  3S3V A;  1AI9 A;  3JSU A;  4FGH A;  2B3Z A;  1RX6 A;  3CLB A;  3INV A;  2W3A A;  3NZA X;  3SRR X;  3L3R A;  4XEC X;  1DAJ A;  4XT7 A;  1RA3 A;  4I13 A;  1DR3 A;  2W9S A;  3JW3 A;  1DYR A;  2LF1 A;  4KL9 A;  4M7U A;  3FRA X;  1RC4 A;  1DG8 A;  4X5G A;  1RX5 A;  2OIP A;  4KEB A;  1BZF A;  5HSR A;  4NX6 A;  4X5J A;  1LUD A;  5HQY A;  5HF2 X;  4M6K A;  3NTZ A;  5ECX A;  3FQO A;  3OAF A;  1J3J A;  3DL5 A;  4G8Z X;  1RB3 A;  1PD9 A;  1S3W A;  3DG8 A;  4LAE X;  2H2Q A;  4HOE A;  3SGY A;  1DRB A;  3E0B A;  1DRA A;  4XT5 A;  1DRE A;  1JUV A;  3F0V X;  4KYA A;  4LAH X;  2W3M A;  4ELE A;  3EX8 A;  4QLF A;  1DYH A;  3NZC X;  3QLX A;  3FY9 X;  1RA1 A;  4GH8 A;  3GI2 A;  3HBB A;  1YHO A;  3F8Z A;  4XT6 A;  4M6J A;  5HVE A;  4DPD A;  4H98 A;  1RA9 A;  4H96 A;  4PSY A;  1DYI A;  3NRR A;  3RG9 A;  2FZI A;  3FQF A;  1PDB A;  3SA1 A;  3NXT A;  3F0U X;  2D5N A;  3EEL A;  3SR5 X;  3IRM A;  4OSG A;  1DRH A;  4IXE D;  3HJ3 A;  4KAK A;  4KY4 A;  4FGG A;  3NXY A;  1DDS A;  3VCO A;  1RX7 A;  4XT4 A;  2OBC A;  4PTH A;  4QJC A;  1IA1 A;  1DLR A;  3FS6 A;  5HT4 A;  3K45 A;  3EEM A;  1S3Y A;  3FRE X;  4EIZ A;  4QI9 A;  3F91 A;  3SRU X;  1DF7 A;  1RA2 A;  2P4G A;  1SEJ A;  3SAI A;  3I8A X;  1DHI A;  3QG2 A;  4ELH A;  3DAU A;  4P68 A;  1LY4 A;  3KFY A;  4KY8 A;  1IA2 A;  2QK8 A;  3KY8 A;  4XT8 A;  1S3U A;  3FYW X;  1DR7 A;  4QHV A;  3IRO A;  1M7A A;  3QLY A;  1DHJ A;  2GD9 A;  3FQC A;  4H97 A;  5CC9 A;  3JWF A;  1U71 A;  1J3I A;  3FL9 A;  4QJZ D;  1DLS A;  2W3B A;  3I3R A;  5ECC A;  1DR4 A;  5CCC A;  1HFR A;  5HSU A;  1CZ3 A;  1KMV A;  3F0S X;  3JTW A;  1DG5 A;  1RH3 A;  3QL0 A;  3M09 A;  1DG7 A;  4LAG X;  4H95 A;  3IA5 A;  3NXX A;  2L28 A;  5HQZ A;  3QLW A;  1VJ3 A;  1RG7 A;  1RX4 A;  5DXV A;  3NU0 A;  4Q6A A;  4KLX A;  1RX3 A;  3UM8 A;  1BOZ A;  3D84 X;  2ANO A;  7DFR A;  2BLA A;  1MVT A;  3FRD X;  2FZJ A;  2XW7 A;  3K47 A;  3TD8 A;  3OCH A;  3JWC A;  1TDR A;  3TQA A;  4TU5 X;  4X5H A;  2CD2 A;  4KJL A;  3GHW A;  1HFP A;  4NX7 A;  1M78 A;  5HUI A;  1HFQ A;  2DHF A;  4DP3 A;  4CD2 A;  2HQP A;  1D1G A;  1RA8 A;  3F0B X;  4KM0 A;  3SA2 A;  4QLG A;  3D80 A;  2C2T A;  2DRC A;  1S3V A;  2ZZA A;  5HT5 A;  4ELG A;  4HOF A;  3N0H A;  5HF0 X;  3SQY X;  4FHB A;  4KJK A;  1MVS A;  3ROA A;  4EIL A;  3NXR A;  3RO9 A;  3F0Q X;  2O7P A;  1RX2 A;  4QLE A;  3R33 A;  3FQV A;  1RB2 A;  4Q67 A;  3Q1H A;  3UM5 A;  3GHV A;  5JG0 X;  3DL6 A;  1DRF A;  4ELF A;  3IA4 A;  4DDR A;  3KJR A;  2HM9 A;  4DPH A;  3K74 A;  5HPB A;  1U72 A;  3DRC A;  3IX9 A;  2W9G A;  3NXV A;  1E26 A;  4KBN A;  2W3W A;  1LY3 A;  3DGA A;  4G3M A;  3LG4 A;  3CL9 A;  3DAT A;  3FYV X;  3NZD A;  8DFR A;  4OR7 A;  3NZB X;  1CD2 A;  4M7V A;  5DFR A;  5JA3 A;  3SRW X;  1DDR A;  3QLZ A;  2W9H A;  3S7A A;  3K2H A;  1DIU A;  3QLS A;  3JVX A;  5U27 A;  4M2X A;  4X5I A; 
#chains in the Genus database with same CATH topology
 1KMS A;  3FRF X;  5FDA A;  3SRQ X;  3GYF A;  3KGY A;  3CD2 A;  1RF7 A;  4KM2 A;  3UM6 A;  3TQ8 A;  1DR1 A;  3QGT A;  1JOL A;  3IRN A;  6DFR A;  4XRB A;  3EIG A;  4X5F A;  3SH2 A;  1OHJ A;  4KD7 A;  3FQ0 A;  3F8Y A;  1DHF A;  3JW5 A;  3SRS X;  3QL3 A;  1RD7 A;  1DR6 A;  1OHK A;  1PD8 A;  4I1N A;  1ZDR A;  2KGK A;  1KLK A;  3QYL A;  3ZPC A;  1RE7 A;  3CSE A;  4PST A;  4Q0E A;  3EEK A;  2AZN A;  4M6L A;  4HA9 A;  5E8Q A;  3FY8 X;  3QFX A;  4IXG X;  3TQB A;  3QLR A;  2HXV A;  1VDR A;  2G6V A;  3DFR A;  1AOE A;  2ANQ A;  3NZ6 X;  1JOM A;  1IA3 A;  3ZPG A;  4KNE A;  2C2S A;  1RX1 A;  4P3Q A;  4KJJ A;  4IXF X;  1AO8 A;  1RX8 A;  2FZH A;  4G95 A;  2ITH A;  2BLB A;  2D0K A;  3FRB X;  3F0X X;  1DYJ A;  1DR2 A;  2INQ A;  3QYO A;  4ELB A;  3NZ9 X;  4RGC A;  5HI6 A;  3S9U A;  5EAJ A;  5U26 A;  4KFJ A;  4DFR A;  1IA4 A;  4XE6 X;  5HVB A;  2BL9 A;  4Q0D A;  3KJS A;  3NXO A;  3EEJ A;  1U70 A;  2BLC A;  4HA7 A;  1DIS A;  3M08 A;  4ECK A;  3TQ9 A;  1J3K A;  3FL8 A;  4PDJ A;  2CIG A;  4EJ1 A;  4EIG A;  3GHC A;  2W3V A;  4PTJ A;  2W9T A;  4HOG A;  1DR5 A;  1RX9 A;  2JYB A;  1M79 A;  4P3R A;  1QZF A;  3FQZ A;  3JWK A;  4LEK X;  3JWM A;  4PSS A;  4P66 A;  3S3V A;  1AI9 A;  3JSU A;  4FGH A;  2B3Z A;  1RX6 A;  3CLB A;  3INV A;  2W3A A;  3NZA X;  3SRR X;  3L3R A;  4XEC X;  1DAJ A;  4XT7 A;  1RA3 A;  4I13 A;  1DR3 A;  2W9S A;  3JW3 A;  1DYR A;  2LF1 A;  4KL9 A;  4M7U A;  3FRA X;  1RC4 A;  1DG8 A;  4X5G A;  1RX5 A;  2OIP A;  4KEB A;  1BZF A;  5HSR A;  4NX6 A;  4X5J A;  1LUD A;  5HQY A;  5HF2 X;  4M6K A;  3NTZ A;  5ECX A;  3FQO A;  3OAF A;  1J3J A;  3DL5 A;  4G8Z X;  1RB3 A;  1PD9 A;  1S3W A;  3DG8 A;  4LAE X;  2H2Q A;  4HOE A;  3SGY A;  1DRB A;  3E0B A;  1DRA A;  4XT5 A;  1DRE A;  1JUV A;  3F0V X;  4KYA A;  4LAH X;  2W3M A;  4ELE A;  3EX8 A;  4QLF A;  1DYH A;  3NZC X;  3QLX A;  3FY9 X;  1RA1 A;  4GH8 A;  3GI2 A;  3HBB A;  1YHO A;  3F8Z A;  4XT6 A;  4M6J A;  5HVE A;  4DPD A;  4H98 A;  1RA9 A;  4H96 A;  4PSY A;  1DYI A;  3NRR A;  3RG9 A;  2FZI A;  3FQF A;  1PDB A;  3SA1 A;  3NXT A;  3F0U X;  2D5N A;  3EEL A;  3SR5 X;  3IRM A;  4OSG A;  1DRH A;  4IXE D;  3HJ3 A;  4KAK A;  4KY4 A;  4FGG A;  3NXY A;  1DDS A;  3VCO A;  1RX7 A;  4XT4 A;  2OBC A;  4PTH A;  4QJC A;  1IA1 A;  1DLR A;  3FS6 A;  5HT4 A;  3K45 A;  3EEM A;  1S3Y A;  3FRE X;  4EIZ A;  4QI9 A;  3F91 A;  3SRU X;  1DF7 A;  1RA2 A;  2P4G A;  1SEJ A;  3SAI A;  3I8A X;  1DHI A;  3QG2 A;  4ELH A;  3DAU A;  4P68 A;  1LY4 A;  3KFY A;  4KY8 A;  1IA2 A;  2QK8 A;  3KY8 A;  4XT8 A;  1S3U A;  3FYW X;  1DR7 A;  4QHV A;  3IRO A;  1M7A A;  3QLY A;  1DHJ A;  2GD9 A;  3FQC A;  4H97 A;  5CC9 A;  3JWF A;  1U71 A;  1J3I A;  3FL9 A;  4QJZ D;  1DLS A;  2W3B A;  3I3R A;  5ECC A;  1DR4 A;  5CCC A;  1HFR A;  5HSU A;  1CZ3 A;  1KMV A;  3F0S X;  3JTW A;  1DG5 A;  1RH3 A;  3QL0 A;  3M09 A;  1DG7 A;  4LAG X;  4H95 A;  3IA5 A;  3NXX A;  2L28 A;  5HQZ A;  3QLW A;  1VJ3 A;  1RG7 A;  1RX4 A;  5DXV A;  3NU0 A;  4Q6A A;  4KLX A;  1RX3 A;  3UM8 A;  1BOZ A;  3D84 X;  2ANO A;  7DFR A;  2BLA A;  1MVT A;  3FRD X;  2FZJ A;  2XW7 A;  3K47 A;  3TD8 A;  3OCH A;  3JWC A;  1TDR A;  3TQA A;  4TU5 X;  4X5H A;  2CD2 A;  4KJL A;  3GHW A;  1HFP A;  4NX7 A;  1M78 A;  5HUI A;  1HFQ A;  2DHF A;  4DP3 A;  4CD2 A;  2HQP A;  1D1G A;  1RA8 A;  3F0B X;  4KM0 A;  3SA2 A;  4QLG A;  3D80 A;  2C2T A;  2DRC A;  1S3V A;  2ZZA A;  5HT5 A;  4ELG A;  4HOF A;  3N0H A;  5HF0 X;  3SQY X;  4FHB A;  4KJK A;  1MVS A;  3ROA A;  4EIL A;  3NXR A;  3RO9 A;  3F0Q X;  2O7P A;  1RX2 A;  4QLE A;  3R33 A;  3FQV A;  1RB2 A;  4Q67 A;  3Q1H A;  3UM5 A;  3GHV A;  5JG0 X;  3DL6 A;  1DRF A;  4ELF A;  3IA4 A;  4DDR A;  3KJR A;  2HM9 A;  4DPH A;  3K74 A;  5HPB A;  1U72 A;  3DRC A;  3IX9 A;  2W9G A;  3NXV A;  1E26 A;  4KBN A;  2W3W A;  1LY3 A;  3DGA A;  4G3M A;  3LG4 A;  3CL9 A;  3DAT A;  3FYV X;  3NZD A;  8DFR A;  4OR7 A;  3NZB X;  1CD2 A;  4M7V A;  5DFR A;  5JA3 A;  3SRW X;  1DDR A;  3QLZ A;  2W9H A;  3S7A A;  3K2H A;  1DIU A;  3QLS A;  3JVX A;  5U27 A;  4M2X A;  4X5I A; 
#chains in the Genus database with same CATH homology
 1KMS A;  3FRF X;  5FDA A;  3SRQ X;  3GYF A;  3KGY A;  3CD2 A;  1RF7 A;  4KM2 A;  3UM6 A;  3TQ8 A;  1DR1 A;  3QGT A;  1JOL A;  3IRN A;  6DFR A;  4XRB A;  3EIG A;  4X5F A;  3SH2 A;  1OHJ A;  4KD7 A;  3FQ0 A;  3F8Y A;  1DHF A;  3JW5 A;  3SRS X;  3QL3 A;  1RD7 A;  1DR6 A;  1OHK A;  1PD8 A;  4I1N A;  1ZDR A;  2KGK A;  1KLK A;  3QYL A;  3ZPC A;  1RE7 A;  3CSE A;  4PST A;  4Q0E A;  3EEK A;  2AZN A;  4M6L A;  4HA9 A;  5E8Q A;  3FY8 X;  3QFX A;  4IXG X;  3TQB A;  3QLR A;  2HXV A;  1VDR A;  2G6V A;  3DFR A;  1AOE A;  2ANQ A;  3NZ6 X;  1JOM A;  1IA3 A;  3ZPG A;  4KNE A;  2C2S A;  1RX1 A;  4P3Q A;  4KJJ A;  4IXF X;  1AO8 A;  1RX8 A;  2FZH A;  4G95 A;  2ITH A;  2BLB A;  2D0K A;  3FRB X;  3F0X X;  1DYJ A;  1DR2 A;  2INQ A;  3QYO A;  4ELB A;  3NZ9 X;  4RGC A;  5HI6 A;  3S9U A;  5EAJ A;  5U26 A;  4KFJ A;  4DFR A;  1IA4 A;  4XE6 X;  5HVB A;  2BL9 A;  4Q0D A;  3KJS A;  3NXO A;  3EEJ A;  1U70 A;  2BLC A;  4HA7 A;  1DIS A;  3M08 A;  4ECK A;  3TQ9 A;  1J3K A;  3FL8 A;  4PDJ A;  2CIG A;  4EJ1 A;  4EIG A;  3GHC A;  2W3V A;  4PTJ A;  2W9T A;  4HOG A;  1DR5 A;  1RX9 A;  2JYB A;  1M79 A;  4P3R A;  1QZF A;  3FQZ A;  3JWK A;  4LEK X;  3JWM A;  4PSS A;  4P66 A;  3S3V A;  1AI9 A;  3JSU A;  4FGH A;  2B3Z A;  1RX6 A;  3CLB A;  3INV A;  2W3A A;  3NZA X;  3SRR X;  3L3R A;  4XEC X;  1DAJ A;  4XT7 A;  1RA3 A;  4I13 A;  1DR3 A;  2W9S A;  3JW3 A;  1DYR A;  2LF1 A;  4KL9 A;  4M7U A;  3FRA X;  1RC4 A;  1DG8 A;  4X5G A;  1RX5 A;  2OIP A;  4KEB A;  1BZF A;  5HSR A;  4NX6 A;  4X5J A;  1LUD A;  5HQY A;  5HF2 X;  4M6K A;  3NTZ A;  5ECX A;  3FQO A;  3OAF A;  1J3J A;  3DL5 A;  4G8Z X;  1RB3 A;  1PD9 A;  1S3W A;  3DG8 A;  4LAE X;  2H2Q A;  4HOE A;  3SGY A;  1DRB A;  3E0B A;  1DRA A;  4XT5 A;  1DRE A;  1JUV A;  3F0V X;  4KYA A;  4LAH X;  2W3M A;  4ELE A;  3EX8 A;  4QLF A;  1DYH A;  3NZC X;  3QLX A;  3FY9 X;  1RA1 A;  4GH8 A;  3GI2 A;  3HBB A;  1YHO A;  3F8Z A;  4XT6 A;  4M6J A;  5HVE A;  4DPD A;  4H98 A;  1RA9 A;  4H96 A;  4PSY A;  1DYI A;  3NRR A;  3RG9 A;  2FZI A;  3FQF A;  1PDB A;  3SA1 A;  3NXT A;  3F0U X;  2D5N A;  3EEL A;  3SR5 X;  3IRM A;  4OSG A;  1DRH A;  4IXE D;  3HJ3 A;  4KAK A;  4KY4 A;  4FGG A;  3NXY A;  1DDS A;  3VCO A;  1RX7 A;  4XT4 A;  2OBC A;  4PTH A;  4QJC A;  1IA1 A;  1DLR A;  3FS6 A;  5HT4 A;  3K45 A;  3EEM A;  1S3Y A;  3FRE X;  4EIZ A;  4QI9 A;  3F91 A;  3SRU X;  1DF7 A;  1RA2 A;  2P4G A;  1SEJ A;  3SAI A;  3I8A X;  1DHI A;  3QG2 A;  4ELH A;  3DAU A;  4P68 A;  1LY4 A;  3KFY A;  4KY8 A;  1IA2 A;  2QK8 A;  3KY8 A;  4XT8 A;  1S3U A;  3FYW X;  1DR7 A;  4QHV A;  3IRO A;  1M7A A;  3QLY A;  1DHJ A;  2GD9 A;  3FQC A;  4H97 A;  5CC9 A;  3JWF A;  1U71 A;  1J3I A;  3FL9 A;  4QJZ D;  1DLS A;  2W3B A;  3I3R A;  5ECC A;  1DR4 A;  5CCC A;  1HFR A;  5HSU A;  1CZ3 A;  1KMV A;  3F0S X;  3JTW A;  1DG5 A;  1RH3 A;  3QL0 A;  3M09 A;  1DG7 A;  4LAG X;  4H95 A;  3IA5 A;  3NXX A;  2L28 A;  5HQZ A;  3QLW A;  1VJ3 A;  1RG7 A;  1RX4 A;  5DXV A;  3NU0 A;  4Q6A A;  4KLX A;  1RX3 A;  3UM8 A;  1BOZ A;  3D84 X;  2ANO A;  7DFR A;  2BLA A;  1MVT A;  3FRD X;  2FZJ A;  2XW7 A;  3K47 A;  3TD8 A;  3OCH A;  3JWC A;  1TDR A;  3TQA A;  4TU5 X;  4X5H A;  2CD2 A;  4KJL A;  3GHW A;  1HFP A;  4NX7 A;  1M78 A;  5HUI A;  1HFQ A;  2DHF A;  4DP3 A;  4CD2 A;  2HQP A;  1D1G A;  1RA8 A;  3F0B X;  4KM0 A;  3SA2 A;  4QLG A;  3D80 A;  2C2T A;  2DRC A;  1S3V A;  2ZZA A;  5HT5 A;  4ELG A;  4HOF A;  3N0H A;  5HF0 X;  3SQY X;  4FHB A;  4KJK A;  1MVS A;  3ROA A;  4EIL A;  3NXR A;  3RO9 A;  3F0Q X;  2O7P A;  1RX2 A;  4QLE A;  3R33 A;  3FQV A;  1RB2 A;  4Q67 A;  3Q1H A;  3UM5 A;  3GHV A;  5JG0 X;  3DL6 A;  1DRF A;  4ELF A;  3IA4 A;  4DDR A;  3KJR A;  2HM9 A;  4DPH A;  3K74 A;  5HPB A;  1U72 A;  3DRC A;  3IX9 A;  2W9G A;  3NXV A;  1E26 A;  4KBN A;  2W3W A;  1LY3 A;  3DGA A;  4G3M A;  3LG4 A;  3CL9 A;  3DAT A;  3FYV X;  3NZD A;  8DFR A;  4OR7 A;  3NZB X;  1CD2 A;  4M7V A;  5DFR A;  5JA3 A;  3SRW X;  1DDR A;  3QLZ A;  2W9H A;  3S7A A;  3K2H A;  1DIU A;  3QLS A;  3JVX A;  5U27 A;  4M2X A;  4X5I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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