1RX8A

Dihydrofolate reductase complexed with folate and 2'-monophosphoadenosine 5'-diphosphoribose
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rx8A00
1BOZA 5HUIA 3TQ8A 3EX8A 1M78A 1LY4A 3VCOA 3NXTA 4I1NA 2AZNA 4PSSA 1DRFA 3E0BA 1PDBA 4PTHA 4G8ZX 3NXYA 3DFRA 1RC4A 2ANQA 3INVA 3QLYA 1RH3A 3QGTA 4H98A 4XT7A 4EILA 4X5GA 3FREX 2GD9A 5DFRA 3JSUA 1D1GA 3CLBA 1S3YA 3IA4A 4IXED 1DR5A 1RX9A 1AO8A 5HQZA 2C2SA 5JA3A 4TU5X 4XT8A 4QJZD 3F8ZA 5U26A 4ELGA 4KEBA 3SRUX 5HVBA 5CC9A 3SAIA 3NZ6X 4EJ1A 3KJSA 3TQAA 1DR6A 3FS6A 2FZIA 1RX8A 3N0HA 4PDJA 1U71A 2ZZAA 3M08A 2W3BA 4EIGA 3SA1A 4NX7A 3SRWX 4EIZA 1DLRA 1AOEA 3TD8A 4HA7A 2B3ZA 4XT6A 3NZBX 1RA2A 1OHJA 3F0XX 4ELFA 1RX3A 2BLAA 2OBCA 5HQYA 1RA1A 4KBNA 4X5FA 5HSRA 4FGHA 1RE7A 4ELEA 4H96A 3FQOA 4Q67A 4KJKA 3EEJA 5ECXA 4KNEA 3NXOA 5HT5A 3NXRA 3SH2A 3ZPCA 3OAFA 4QJCA 3FL9A 3JWCA 4X5IA 3SRQX 3EIGA 3QLXA 3ZPGA 4XT5A 1DHFA 3K2HA 1RB2A 4Q6AA 1JUVA 2FZJA 3QL3A 4X5HA 2HXVA 4M6LA 4P68A 3SR5X 3EEMA 4KJLA 1RX1A 3IA5A 5FDAA 4DPHA 1DRBA 3QG2A 3QFXA 4KM2A 1RB3A 4H97A 2W9GA 3FQZA 3UM8A 1U70A 4Q0DA 3JTWA 3IROA 1RX5A 1DR3A 4P66A 1RG7A 2DHFA 4XT4A 8DFRA 3GHVA 4IXGX 3S3VA 1MVTA 1RA8A 4NX6A 3GYFA 2CD2A 3GHCA 4M2XA 3S7AA 2G6VA 1DHJA 3QL0A 5CCCA 4IXFX 4KM0A 3ROAA 2INQA 5HI6A 4KFJA 4P3RA 3L3RA 5HPBA 5HSUA 3NZCX 2W9HA 4DPDA 3UM5A 1DYHA 3I3RA 1M79A 2QK8A 3FYWX 4LAHX 1RA3A 3QLZA 1RX6A 3I8AX 2HM9A 1DAJA 2W3AA 5ECCA 1E26A 1RA9A 4QHVA 3F0QX 4KJJA 4KLXA 3SQYX 1U72A 1VDRA 3NZAX 1HFQA 1DDSA 3SRRX 2BLCA 1OHKA 2BLBA 5HF0X 1QZFA 4CD2A 2KGKA 3LG4A 3TQBA 1JOLA 1DRAA 4QLEA 2ITHA 2D5NA 3DATA 4PTJA 1RX2A 3EEKA 3QLWA 1DF7A 1S3VA 4X5JA 3CSEA 1M7AA 2FZHA 4GH8A 4HOEA 4HA9A 3CD2A 3FYVX 3F0SX 3HJ3A 3NZ9X 4LAEX 4OR7A 1BZFA 5U27A 3S9UA 3DRCA 1PD8A 1IA1A 4KY4A 1DR4A 3F0UX 3FRDX 1J3JA 3GHWA 3FQFA 3F0VX 1CD2A 2CIGA 3IRMA 3NTZA 3NRRA 3CL9A 1DYRA 3KFYA 1DR1A 5JG0X 4M6KA 4ELBA 3SGYA 5EAJA 6DFRA 2L28A 1IA4A 4I13A 4OSGA 2W9SA 2W3VA 3DL5A 3JWMA 3GI2A 4M7UA 3DL6A 3FY9X 3KJRA 5DXVA 1DG8A 2W3WA 4RGCA 1DIUA 1RF7A 1DG7A 4M7VA 3FQCA 1RX4A 1ZDRA 3JW3A 4G95A 4QLFA 4PSYA 2OIPA 1JOMA 1DYIA 2ANOA 1DRHA 4G3MA 3RO9A 1S3WA 1J3KA 3QLRA 3NXVA 4XE6X 2W9TA 3SA2A 1KLKA 5E8QA 4PSTA 3IX9A 3KY8A 1MVSA 3DG8A 1HFPA 3F91A 3QYLA 1DR7A 1DDRA 1J3IA 4ELHA 2C2TA 7DFRA 3HBBA 1KMSA 3K45A 4KAKA 1PD9A 1DG5A 3R33A 1TDRA 3SRSX 4Q0EA 3FL8A 1SEJA 3D84X 3KGYA 1AI9A 2P4GA 4H95A 4KD7A 2XW7A 4FHBA 4DDRA 3UM6A 2D0KA 3JWFA 3NXXA 3NZDA 4HOGA 3FRFX 1KMVA 4ECKA 4LEKX 3FQ0A 4XECX 2W3MA 4FGGA 4DFRA 3IRNA 1DHIA 4M6JA 1DISA 4KL9A 2HQPA 4DP3A 1IA3A 3DGAA 3OCHA 3K74A 3Q1HA 3F0BX 1LUDA 4KY8A 1IA2A 1DR2A 4P3QA 3JVXA 3FRAX 2JYBA 1CZ3A 5HT4A 3EELA 3M09A 3FY8X 1RD7A 5HF2X 3DAUA 1LY3A 4HOFA 3NU0A 1VJ3A 4QI9A 1YHOA 3F8YA 3TQ9A 2DRCA 5HVEA 3K47A 3FQVA 4XRBA 2LF1A 3D80A 1HFRA 1S3UA 3JW5A 4QLGA 4KYAA 1DYJA 2BL9A 1DLSA 4LAGX 1RX7A 1DREA 3QYOA 3QLSA 3JWKA 2O7PA 2H2QA 3RG9A 3FRBX
chains in the Genus database with same CATH superfamily
1BOZA 5HUIA 3TQ8A 3EX8A 1M78A 1LY4A 3VCOA 3NXTA 4I1NA 2AZNA 4PSSA 1DRFA 3E0BA 1PDBA 4PTHA 4G8ZX 3NXYA 3DFRA 1RC4A 2ANQA 3INVA 3QLYA 1RH3A 3QGTA 4H98A 4XT7A 4EILA 4X5GA 3FREX 2GD9A 5DFRA 3JSUA 1D1GA 3CLBA 1S3YA 3IA4A 4IXED 1DR5A 1RX9A 1AO8A 5HQZA 2C2SA 5JA3A 4TU5X 4XT8A 4QJZD 3F8ZA 5U26A 4ELGA 4KEBA 3SRUX 5HVBA 5CC9A 3SAIA 3NZ6X 4EJ1A 3KJSA 3TQAA 1DR6A 3FS6A 2FZIA 1RX8A 3N0HA 4PDJA 1U71A 2ZZAA 3M08A 2W3BA 4EIGA 3SA1A 4NX7A 3SRWX 4EIZA 1DLRA 1AOEA 3TD8A 4HA7A 2B3ZA 4XT6A 3NZBX 1RA2A 1OHJA 3F0XX 4ELFA 1RX3A 2BLAA 2OBCA 5HQYA 1RA1A 4KBNA 4X5FA 5HSRA 4FGHA 1RE7A 4ELEA 4H96A 3FQOA 4Q67A 4KJKA 3EEJA 5ECXA 4KNEA 3NXOA 5HT5A 3NXRA 3SH2A 3ZPCA 3OAFA 4QJCA 3FL9A 3JWCA 4X5IA 3SRQX 3EIGA 3QLXA 3ZPGA 4XT5A 1DHFA 3K2HA 1RB2A 4Q6AA 1JUVA 2FZJA 3QL3A 4X5HA 2HXVA 4M6LA 4P68A 3SR5X 3EEMA 4KJLA 1RX1A 3IA5A 5FDAA 4DPHA 1DRBA 3QG2A 3QFXA 4KM2A 1RB3A 4H97A 2W9GA 3FQZA 3UM8A 1U70A 4Q0DA 3JTWA 3IROA 1RX5A 1DR3A 4P66A 1RG7A 2DHFA 4XT4A 8DFRA 3GHVA 4IXGX 3S3VA 1MVTA 1RA8A 4NX6A 3GYFA 2CD2A 3GHCA 4M2XA 3S7AA 2G6VA 1DHJA 3QL0A 5CCCA 4IXFX 4KM0A 3ROAA 2INQA 5HI6A 4KFJA 4P3RA 3L3RA 5HPBA 5HSUA 3NZCX 2W9HA 4DPDA 3UM5A 1DYHA 3I3RA 1M79A 2QK8A 3FYWX 4LAHX 1RA3A 3QLZA 1RX6A 3I8AX 2HM9A 1DAJA 2W3AA 5ECCA 1E26A 1RA9A 4QHVA 3F0QX 4KJJA 4KLXA 3SQYX 1U72A 1VDRA 3NZAX 1HFQA 1DDSA 3SRRX 2BLCA 1OHKA 2BLBA 5HF0X 1QZFA 4CD2A 2KGKA 3LG4A 3TQBA 1JOLA 1DRAA 4QLEA 2ITHA 2D5NA 3DATA 4PTJA 1RX2A 3EEKA 3QLWA 1DF7A 1S3VA 4X5JA 3CSEA 1M7AA 2FZHA 4GH8A 4HOEA 4HA9A 3CD2A 3FYVX 3F0SX 3HJ3A 3NZ9X 4LAEX 4OR7A 1BZFA 5U27A 3S9UA 3DRCA 1PD8A 1IA1A 4KY4A 1DR4A 3F0UX 3FRDX 1J3JA 3GHWA 3FQFA 3F0VX 1CD2A 2CIGA 3IRMA 3NTZA 3NRRA 3CL9A 1DYRA 3KFYA 1DR1A 5JG0X 4M6KA 4ELBA 3SGYA 5EAJA 6DFRA 2L28A 1IA4A 4I13A 4OSGA 2W9SA 2W3VA 3DL5A 3JWMA 3GI2A 4M7UA 3DL6A 3FY9X 3KJRA 5DXVA 1DG8A 2W3WA 4RGCA 1DIUA 1RF7A 1DG7A 4M7VA 3FQCA 1RX4A 1ZDRA 3JW3A 4G95A 4QLFA 4PSYA 2OIPA 1JOMA 1DYIA 2ANOA 1DRHA 4G3MA 3RO9A 1S3WA 1J3KA 3QLRA 3NXVA 4XE6X 2W9TA 3SA2A 1KLKA 5E8QA 4PSTA 3IX9A 3KY8A 1MVSA 3DG8A 1HFPA 3F91A 3QYLA 1DR7A 1DDRA 1J3IA 4ELHA 2C2TA 7DFRA 3HBBA 1KMSA 3K45A 4KAKA 1PD9A 1DG5A 3R33A 1TDRA 3SRSX 4Q0EA 3FL8A 1SEJA 3D84X 3KGYA 1AI9A 2P4GA 4H95A 4KD7A 2XW7A 4FHBA 4DDRA 3UM6A 2D0KA 3JWFA 3NXXA 3NZDA 4HOGA 3FRFX 1KMVA 4ECKA 4LEKX 3FQ0A 4XECX 2W3MA 4FGGA 4DFRA 3IRNA 1DHIA 4M6JA 1DISA 4KL9A 2HQPA 4DP3A 1IA3A 3DGAA 3OCHA 3K74A 3Q1HA 3F0BX 1LUDA 4KY8A 1IA2A 1DR2A 4P3QA 3JVXA 3FRAX 2JYBA 1CZ3A 5HT4A 3EELA 3M09A 3FY8X 1RD7A 5HF2X 3DAUA 1LY3A 4HOFA 3NU0A 1VJ3A 4QI9A 1YHOA 3F8YA 3TQ9A 2DRCA 5HVEA 3K47A 3FQVA 4XRBA 2LF1A 3D80A 1HFRA 1S3UA 3JW5A 4QLGA 4KYAA 1DYJA 2BL9A 1DLSA 4LAGX 1RX7A 1DREA 3QYOA 3QLSA 3JWKA 2O7PA 2H2QA 3RG9A 3FRBX
chains in the Genus database with same CATH topology
1BOZA 5HUIA 3TQ8A 3EX8A 1M78A 1LY4A 3VCOA 3NXTA 4I1NA 2AZNA 4PSSA 1DRFA 3E0BA 1PDBA 4PTHA 4G8ZX 3NXYA 3DFRA 1RC4A 2ANQA 3INVA 3QLYA 1RH3A 3QGTA 4H98A 4XT7A 4EILA 4X5GA 3FREX 2GD9A 5DFRA 3JSUA 1D1GA 3CLBA 1S3YA 3IA4A 4IXED 1DR5A 1RX9A 1AO8A 5HQZA 2C2SA 5JA3A 4TU5X 4XT8A 4QJZD 3F8ZA 5U26A 4ELGA 4KEBA 3SRUX 5HVBA 5CC9A 3SAIA 3NZ6X 4EJ1A 3KJSA 3TQAA 1DR6A 3FS6A 2FZIA 1RX8A 3N0HA 4PDJA 1U71A 2ZZAA 3M08A 2W3BA 4EIGA 3SA1A 4NX7A 3SRWX 4EIZA 1DLRA 1AOEA 3TD8A 4HA7A 2B3ZA 4XT6A 3NZBX 1RA2A 1OHJA 3F0XX 4ELFA 1RX3A 2BLAA 2OBCA 5HQYA 1RA1A 4KBNA 4X5FA 5HSRA 4FGHA 1RE7A 4ELEA 4H96A 3FQOA 4Q67A 4KJKA 3EEJA 5ECXA 4KNEA 3NXOA 5HT5A 3NXRA 3SH2A 3ZPCA 3OAFA 4QJCA 3FL9A 3JWCA 4X5IA 3SRQX 3EIGA 3QLXA 3ZPGA 4XT5A 1DHFA 3K2HA 1RB2A 4Q6AA 1JUVA 2FZJA 3QL3A 4X5HA 2HXVA 4M6LA 4P68A 3SR5X 3EEMA 4KJLA 1RX1A 3IA5A 5FDAA 4DPHA 1DRBA 3QG2A 3QFXA 4KM2A 1RB3A 4H97A 2W9GA 3FQZA 3UM8A 1U70A 4Q0DA 3JTWA 3IROA 1RX5A 1DR3A 4P66A 1RG7A 2DHFA 4XT4A 8DFRA 3GHVA 4IXGX 3S3VA 1MVTA 1RA8A 4NX6A 3GYFA 2CD2A 3GHCA 4M2XA 3S7AA 2G6VA 1DHJA 3QL0A 5CCCA 4IXFX 4KM0A 3ROAA 2INQA 5HI6A 4KFJA 4P3RA 3L3RA 5HPBA 5HSUA 3NZCX 2W9HA 4DPDA 3UM5A 1DYHA 3I3RA 1M79A 2QK8A 3FYWX 4LAHX 1RA3A 3QLZA 1RX6A 3I8AX 2HM9A 1DAJA 2W3AA 5ECCA 1E26A 1RA9A 4QHVA 3F0QX 4KJJA 4KLXA 3SQYX 1U72A 1VDRA 3NZAX 1HFQA 1DDSA 3SRRX 2BLCA 1OHKA 2BLBA 5HF0X 1QZFA 4CD2A 2KGKA 3LG4A 3TQBA 1JOLA 1DRAA 4QLEA 2ITHA 2D5NA 3DATA 4PTJA 1RX2A 3EEKA 3QLWA 1DF7A 1S3VA 4X5JA 3CSEA 1M7AA 2FZHA 4GH8A 4HOEA 4HA9A 3CD2A 3FYVX 3F0SX 3HJ3A 3NZ9X 4LAEX 4OR7A 1BZFA 5U27A 3S9UA 3DRCA 1PD8A 1IA1A 4KY4A 1DR4A 3F0UX 3FRDX 1J3JA 3GHWA 3FQFA 3F0VX 1CD2A 2CIGA 3IRMA 3NTZA 3NRRA 3CL9A 1DYRA 3KFYA 1DR1A 5JG0X 4M6KA 4ELBA 3SGYA 5EAJA 6DFRA 2L28A 1IA4A 4I13A 4OSGA 2W9SA 2W3VA 3DL5A 3JWMA 3GI2A 4M7UA 3DL6A 3FY9X 3KJRA 5DXVA 1DG8A 2W3WA 4RGCA 1DIUA 1RF7A 1DG7A 4M7VA 3FQCA 1RX4A 1ZDRA 3JW3A 4G95A 4QLFA 4PSYA 2OIPA 1JOMA 1DYIA 2ANOA 1DRHA 4G3MA 3RO9A 1S3WA 1J3KA 3QLRA 3NXVA 4XE6X 2W9TA 3SA2A 1KLKA 5E8QA 4PSTA 3IX9A 3KY8A 1MVSA 3DG8A 1HFPA 3F91A 3QYLA 1DR7A 1DDRA 1J3IA 4ELHA 2C2TA 7DFRA 3HBBA 1KMSA 3K45A 4KAKA 1PD9A 1DG5A 3R33A 1TDRA 3SRSX 4Q0EA 3FL8A 1SEJA 3D84X 3KGYA 1AI9A 2P4GA 4H95A 4KD7A 2XW7A 4FHBA 4DDRA 3UM6A 2D0KA 3JWFA 3NXXA 3NZDA 4HOGA 3FRFX 1KMVA 4ECKA 4LEKX 3FQ0A 4XECX 2W3MA 4FGGA 4DFRA 3IRNA 1DHIA 4M6JA 1DISA 4KL9A 2HQPA 4DP3A 1IA3A 3DGAA 3OCHA 3K74A 3Q1HA 3F0BX 1LUDA 4KY8A 1IA2A 1DR2A 4P3QA 3JVXA 3FRAX 2JYBA 1CZ3A 5HT4A 3EELA 3M09A 3FY8X 1RD7A 5HF2X 3DAUA 1LY3A 4HOFA 3NU0A 1VJ3A 4QI9A 1YHOA 3F8YA 3TQ9A 2DRCA 5HVEA 3K47A 3FQVA 4XRBA 2LF1A 3D80A 1HFRA 1S3UA 3JW5A 4QLGA 4KYAA 1DYJA 2BL9A 1DLSA 4LAGX 1RX7A 1DREA 3QYOA 3QLSA 3JWKA 2O7PA 2H2QA 3RG9A 3FRBX
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1BOZ A;  5HUI A;  3TQ8 A;  3EX8 A;  1M78 A;  1LY4 A;  3VCO A;  3NXT A;  4I1N A;  2AZN A;  4PSS A;  1DRF A;  3E0B A;  1PDB A;  4PTH A;  4G8Z X;  3NXY A;  3DFR A;  1RC4 A;  2ANQ A;  3INV A;  3QLY A;  1RH3 A;  3QGT A;  4H98 A;  4XT7 A;  4EIL A;  4X5G A;  3FRE X;  2GD9 A;  5DFR A;  3JSU A;  1D1G A;  3CLB A;  1S3Y A;  3IA4 A;  4IXE D;  1DR5 A;  1RX9 A;  1AO8 A;  5HQZ A;  2C2S A;  5JA3 A;  4TU5 X;  4XT8 A;  4QJZ D;  3F8Z A;  5U26 A;  4ELG A;  4KEB A;  3SRU X;  5HVB A;  5CC9 A;  3SAI A;  3NZ6 X;  4EJ1 A;  3KJS A;  3TQA A;  1DR6 A;  3FS6 A;  2FZI A;  1RX8 A;  3N0H A;  4PDJ A;  1U71 A;  2ZZA A;  3M08 A;  2W3B A;  4EIG A;  3SA1 A;  4NX7 A;  3SRW X;  4EIZ A;  1DLR A;  1AOE A;  3TD8 A;  4HA7 A;  2B3Z A;  4XT6 A;  3NZB X;  1RA2 A;  1OHJ A;  3F0X X;  4ELF A;  1RX3 A;  2BLA A;  2OBC A;  5HQY A;  1RA1 A;  4KBN A;  4X5F A;  5HSR A;  4FGH A;  1RE7 A;  4ELE A;  4H96 A;  3FQO A;  4Q67 A;  4KJK A;  3EEJ A;  5ECX A;  4KNE A;  3NXO A;  5HT5 A;  3NXR A;  3SH2 A;  3ZPC A;  3OAF A;  4QJC A;  3FL9 A;  3JWC A;  4X5I A;  3SRQ X;  3EIG A;  3QLX A;  3ZPG A;  4XT5 A;  1DHF A;  3K2H A;  1RB2 A;  4Q6A A;  1JUV A;  2FZJ A;  3QL3 A;  4X5H A;  2HXV A;  4M6L A;  4P68 A;  3SR5 X;  3EEM A;  4KJL A;  1RX1 A;  3IA5 A;  5FDA A;  4DPH A;  1DRB A;  3QG2 A;  3QFX A;  4KM2 A;  1RB3 A;  4H97 A;  2W9G A;  3FQZ A;  3UM8 A;  1U70 A;  4Q0D A;  3JTW A;  3IRO A;  1RX5 A;  1DR3 A;  4P66 A;  1RG7 A;  2DHF A;  4XT4 A;  8DFR A;  3GHV A;  4IXG X;  3S3V A;  1MVT A;  1RA8 A;  4NX6 A;  3GYF A;  2CD2 A;  3GHC A;  4M2X A;  3S7A A;  2G6V A;  1DHJ A;  3QL0 A;  5CCC A;  4IXF X;  4KM0 A;  3ROA A;  2INQ A;  5HI6 A;  4KFJ A;  4P3R A;  3L3R A;  5HPB A;  5HSU A;  3NZC X;  2W9H A;  4DPD A;  3UM5 A;  1DYH A;  3I3R A;  1M79 A;  2QK8 A;  3FYW X;  4LAH X;  1RA3 A;  3QLZ A;  1RX6 A;  3I8A X;  2HM9 A;  1DAJ A;  2W3A A;  5ECC A;  1E26 A;  1RA9 A;  4QHV A;  3F0Q X;  4KJJ A;  4KLX A;  3SQY X;  1U72 A;  1VDR A;  3NZA X;  1HFQ A;  1DDS A;  3SRR X;  2BLC A;  1OHK A;  2BLB A;  5HF0 X;  1QZF A;  4CD2 A;  2KGK A;  3LG4 A;  3TQB A;  1JOL A;  1DRA A;  4QLE A;  2ITH A;  2D5N A;  3DAT A;  4PTJ A;  1RX2 A;  3EEK A;  3QLW A;  1DF7 A;  1S3V A;  4X5J A;  3CSE A;  1M7A A;  2FZH A;  4GH8 A;  4HOE A;  4HA9 A;  3CD2 A;  3FYV X;  3F0S X;  3HJ3 A;  3NZ9 X;  4LAE X;  4OR7 A;  1BZF A;  5U27 A;  3S9U A;  3DRC A;  1PD8 A;  1IA1 A;  4KY4 A;  1DR4 A;  3F0U X;  3FRD X;  1J3J A;  3GHW A;  3FQF A;  3F0V X;  1CD2 A;  2CIG A;  3IRM A;  3NTZ A;  3NRR A;  3CL9 A;  1DYR A;  3KFY A;  1DR1 A;  5JG0 X;  4M6K A;  4ELB A;  3SGY A;  5EAJ A;  6DFR A;  2L28 A;  1IA4 A;  4I13 A;  4OSG A;  2W9S A;  2W3V A;  3DL5 A;  3JWM A;  3GI2 A;  4M7U A;  3DL6 A;  3FY9 X;  3KJR A;  5DXV A;  1DG8 A;  2W3W A;  4RGC A;  1DIU A;  1RF7 A;  1DG7 A;  4M7V A;  3FQC A;  1RX4 A;  1ZDR A;  3JW3 A;  4G95 A;  4QLF A;  4PSY A;  2OIP A;  1JOM A;  1DYI A;  2ANO A;  1DRH A;  4G3M A;  3RO9 A;  1S3W A;  1J3K A;  3QLR A;  3NXV A;  4XE6 X;  2W9T A;  3SA2 A;  1KLK A;  5E8Q A;  4PST A;  3IX9 A;  3KY8 A;  1MVS A;  3DG8 A;  1HFP A;  3F91 A;  3QYL A;  1DR7 A;  1DDR A;  1J3I A;  4ELH A;  2C2T A;  7DFR A;  3HBB A;  1KMS A;  3K45 A;  4KAK A;  1PD9 A;  1DG5 A;  3R33 A;  1TDR A;  3SRS X;  4Q0E A;  3FL8 A;  1SEJ A;  3D84 X;  3KGY A;  1AI9 A;  2P4G A;  4H95 A;  4KD7 A;  2XW7 A;  4FHB A;  4DDR A;  3UM6 A;  2D0K A;  3JWF A;  3NXX A;  3NZD A;  4HOG A;  3FRF X;  1KMV A;  4ECK A;  4LEK X;  3FQ0 A;  4XEC X;  2W3M A;  4FGG A;  4DFR A;  3IRN A;  1DHI A;  4M6J A;  1DIS A;  4KL9 A;  2HQP A;  4DP3 A;  1IA3 A;  3DGA A;  3OCH A;  3K74 A;  3Q1H A;  3F0B X;  1LUD A;  4KY8 A;  1IA2 A;  1DR2 A;  4P3Q A;  3JVX A;  3FRA X;  2JYB A;  1CZ3 A;  5HT4 A;  3EEL A;  3M09 A;  3FY8 X;  1RD7 A;  5HF2 X;  3DAU A;  1LY3 A;  4HOF A;  3NU0 A;  1VJ3 A;  4QI9 A;  1YHO A;  3F8Y A;  3TQ9 A;  2DRC A;  5HVE A;  3K47 A;  3FQV A;  4XRB A;  2LF1 A;  3D80 A;  1HFR A;  1S3U A;  3JW5 A;  4QLG A;  4KYA A;  1DYJ A;  2BL9 A;  1DLS A;  4LAG X;  1RX7 A;  1DRE A;  3QYO A;  3QLS A;  3JWK A;  2O7P A;  2H2Q A;  3RG9 A;  3FRB X; 
#chains in the Genus database with same CATH topology
 1BOZ A;  5HUI A;  3TQ8 A;  3EX8 A;  1M78 A;  1LY4 A;  3VCO A;  3NXT A;  4I1N A;  2AZN A;  4PSS A;  1DRF A;  3E0B A;  1PDB A;  4PTH A;  4G8Z X;  3NXY A;  3DFR A;  1RC4 A;  2ANQ A;  3INV A;  3QLY A;  1RH3 A;  3QGT A;  4H98 A;  4XT7 A;  4EIL A;  4X5G A;  3FRE X;  2GD9 A;  5DFR A;  3JSU A;  1D1G A;  3CLB A;  1S3Y A;  3IA4 A;  4IXE D;  1DR5 A;  1RX9 A;  1AO8 A;  5HQZ A;  2C2S A;  5JA3 A;  4TU5 X;  4XT8 A;  4QJZ D;  3F8Z A;  5U26 A;  4ELG A;  4KEB A;  3SRU X;  5HVB A;  5CC9 A;  3SAI A;  3NZ6 X;  4EJ1 A;  3KJS A;  3TQA A;  1DR6 A;  3FS6 A;  2FZI A;  1RX8 A;  3N0H A;  4PDJ A;  1U71 A;  2ZZA A;  3M08 A;  2W3B A;  4EIG A;  3SA1 A;  4NX7 A;  3SRW X;  4EIZ A;  1DLR A;  1AOE A;  3TD8 A;  4HA7 A;  2B3Z A;  4XT6 A;  3NZB X;  1RA2 A;  1OHJ A;  3F0X X;  4ELF A;  1RX3 A;  2BLA A;  2OBC A;  5HQY A;  1RA1 A;  4KBN A;  4X5F A;  5HSR A;  4FGH A;  1RE7 A;  4ELE A;  4H96 A;  3FQO A;  4Q67 A;  4KJK A;  3EEJ A;  5ECX A;  4KNE A;  3NXO A;  5HT5 A;  3NXR A;  3SH2 A;  3ZPC A;  3OAF A;  4QJC A;  3FL9 A;  3JWC A;  4X5I A;  3SRQ X;  3EIG A;  3QLX A;  3ZPG A;  4XT5 A;  1DHF A;  3K2H A;  1RB2 A;  4Q6A A;  1JUV A;  2FZJ A;  3QL3 A;  4X5H A;  2HXV A;  4M6L A;  4P68 A;  3SR5 X;  3EEM A;  4KJL A;  1RX1 A;  3IA5 A;  5FDA A;  4DPH A;  1DRB A;  3QG2 A;  3QFX A;  4KM2 A;  1RB3 A;  4H97 A;  2W9G A;  3FQZ A;  3UM8 A;  1U70 A;  4Q0D A;  3JTW A;  3IRO A;  1RX5 A;  1DR3 A;  4P66 A;  1RG7 A;  2DHF A;  4XT4 A;  8DFR A;  3GHV A;  4IXG X;  3S3V A;  1MVT A;  1RA8 A;  4NX6 A;  3GYF A;  2CD2 A;  3GHC A;  4M2X A;  3S7A A;  2G6V A;  1DHJ A;  3QL0 A;  5CCC A;  4IXF X;  4KM0 A;  3ROA A;  2INQ A;  5HI6 A;  4KFJ A;  4P3R A;  3L3R A;  5HPB A;  5HSU A;  3NZC X;  2W9H A;  4DPD A;  3UM5 A;  1DYH A;  3I3R A;  1M79 A;  2QK8 A;  3FYW X;  4LAH X;  1RA3 A;  3QLZ A;  1RX6 A;  3I8A X;  2HM9 A;  1DAJ A;  2W3A A;  5ECC A;  1E26 A;  1RA9 A;  4QHV A;  3F0Q X;  4KJJ A;  4KLX A;  3SQY X;  1U72 A;  1VDR A;  3NZA X;  1HFQ A;  1DDS A;  3SRR X;  2BLC A;  1OHK A;  2BLB A;  5HF0 X;  1QZF A;  4CD2 A;  2KGK A;  3LG4 A;  3TQB A;  1JOL A;  1DRA A;  4QLE A;  2ITH A;  2D5N A;  3DAT A;  4PTJ A;  1RX2 A;  3EEK A;  3QLW A;  1DF7 A;  1S3V A;  4X5J A;  3CSE A;  1M7A A;  2FZH A;  4GH8 A;  4HOE A;  4HA9 A;  3CD2 A;  3FYV X;  3F0S X;  3HJ3 A;  3NZ9 X;  4LAE X;  4OR7 A;  1BZF A;  5U27 A;  3S9U A;  3DRC A;  1PD8 A;  1IA1 A;  4KY4 A;  1DR4 A;  3F0U X;  3FRD X;  1J3J A;  3GHW A;  3FQF A;  3F0V X;  1CD2 A;  2CIG A;  3IRM A;  3NTZ A;  3NRR A;  3CL9 A;  1DYR A;  3KFY A;  1DR1 A;  5JG0 X;  4M6K A;  4ELB A;  3SGY A;  5EAJ A;  6DFR A;  2L28 A;  1IA4 A;  4I13 A;  4OSG A;  2W9S A;  2W3V A;  3DL5 A;  3JWM A;  3GI2 A;  4M7U A;  3DL6 A;  3FY9 X;  3KJR A;  5DXV A;  1DG8 A;  2W3W A;  4RGC A;  1DIU A;  1RF7 A;  1DG7 A;  4M7V A;  3FQC A;  1RX4 A;  1ZDR A;  3JW3 A;  4G95 A;  4QLF A;  4PSY A;  2OIP A;  1JOM A;  1DYI A;  2ANO A;  1DRH A;  4G3M A;  3RO9 A;  1S3W A;  1J3K A;  3QLR A;  3NXV A;  4XE6 X;  2W9T A;  3SA2 A;  1KLK A;  5E8Q A;  4PST A;  3IX9 A;  3KY8 A;  1MVS A;  3DG8 A;  1HFP A;  3F91 A;  3QYL A;  1DR7 A;  1DDR A;  1J3I A;  4ELH A;  2C2T A;  7DFR A;  3HBB A;  1KMS A;  3K45 A;  4KAK A;  1PD9 A;  1DG5 A;  3R33 A;  1TDR A;  3SRS X;  4Q0E A;  3FL8 A;  1SEJ A;  3D84 X;  3KGY A;  1AI9 A;  2P4G A;  4H95 A;  4KD7 A;  2XW7 A;  4FHB A;  4DDR A;  3UM6 A;  2D0K A;  3JWF A;  3NXX A;  3NZD A;  4HOG A;  3FRF X;  1KMV A;  4ECK A;  4LEK X;  3FQ0 A;  4XEC X;  2W3M A;  4FGG A;  4DFR A;  3IRN A;  1DHI A;  4M6J A;  1DIS A;  4KL9 A;  2HQP A;  4DP3 A;  1IA3 A;  3DGA A;  3OCH A;  3K74 A;  3Q1H A;  3F0B X;  1LUD A;  4KY8 A;  1IA2 A;  1DR2 A;  4P3Q A;  3JVX A;  3FRA X;  2JYB A;  1CZ3 A;  5HT4 A;  3EEL A;  3M09 A;  3FY8 X;  1RD7 A;  5HF2 X;  3DAU A;  1LY3 A;  4HOF A;  3NU0 A;  1VJ3 A;  4QI9 A;  1YHO A;  3F8Y A;  3TQ9 A;  2DRC A;  5HVE A;  3K47 A;  3FQV A;  4XRB A;  2LF1 A;  3D80 A;  1HFR A;  1S3U A;  3JW5 A;  4QLG A;  4KYA A;  1DYJ A;  2BL9 A;  1DLS A;  4LAG X;  1RX7 A;  1DRE A;  3QYO A;  3QLS A;  3JWK A;  2O7P A;  2H2Q A;  3RG9 A;  3FRB X; 
#chains in the Genus database with same CATH homology
 1BOZ A;  5HUI A;  3TQ8 A;  3EX8 A;  1M78 A;  1LY4 A;  3VCO A;  3NXT A;  4I1N A;  2AZN A;  4PSS A;  1DRF A;  3E0B A;  1PDB A;  4PTH A;  4G8Z X;  3NXY A;  3DFR A;  1RC4 A;  2ANQ A;  3INV A;  3QLY A;  1RH3 A;  3QGT A;  4H98 A;  4XT7 A;  4EIL A;  4X5G A;  3FRE X;  2GD9 A;  5DFR A;  3JSU A;  1D1G A;  3CLB A;  1S3Y A;  3IA4 A;  4IXE D;  1DR5 A;  1RX9 A;  1AO8 A;  5HQZ A;  2C2S A;  5JA3 A;  4TU5 X;  4XT8 A;  4QJZ D;  3F8Z A;  5U26 A;  4ELG A;  4KEB A;  3SRU X;  5HVB A;  5CC9 A;  3SAI A;  3NZ6 X;  4EJ1 A;  3KJS A;  3TQA A;  1DR6 A;  3FS6 A;  2FZI A;  1RX8 A;  3N0H A;  4PDJ A;  1U71 A;  2ZZA A;  3M08 A;  2W3B A;  4EIG A;  3SA1 A;  4NX7 A;  3SRW X;  4EIZ A;  1DLR A;  1AOE A;  3TD8 A;  4HA7 A;  2B3Z A;  4XT6 A;  3NZB X;  1RA2 A;  1OHJ A;  3F0X X;  4ELF A;  1RX3 A;  2BLA A;  2OBC A;  5HQY A;  1RA1 A;  4KBN A;  4X5F A;  5HSR A;  4FGH A;  1RE7 A;  4ELE A;  4H96 A;  3FQO A;  4Q67 A;  4KJK A;  3EEJ A;  5ECX A;  4KNE A;  3NXO A;  5HT5 A;  3NXR A;  3SH2 A;  3ZPC A;  3OAF A;  4QJC A;  3FL9 A;  3JWC A;  4X5I A;  3SRQ X;  3EIG A;  3QLX A;  3ZPG A;  4XT5 A;  1DHF A;  3K2H A;  1RB2 A;  4Q6A A;  1JUV A;  2FZJ A;  3QL3 A;  4X5H A;  2HXV A;  4M6L A;  4P68 A;  3SR5 X;  3EEM A;  4KJL A;  1RX1 A;  3IA5 A;  5FDA A;  4DPH A;  1DRB A;  3QG2 A;  3QFX A;  4KM2 A;  1RB3 A;  4H97 A;  2W9G A;  3FQZ A;  3UM8 A;  1U70 A;  4Q0D A;  3JTW A;  3IRO A;  1RX5 A;  1DR3 A;  4P66 A;  1RG7 A;  2DHF A;  4XT4 A;  8DFR A;  3GHV A;  4IXG X;  3S3V A;  1MVT A;  1RA8 A;  4NX6 A;  3GYF A;  2CD2 A;  3GHC A;  4M2X A;  3S7A A;  2G6V A;  1DHJ A;  3QL0 A;  5CCC A;  4IXF X;  4KM0 A;  3ROA A;  2INQ A;  5HI6 A;  4KFJ A;  4P3R A;  3L3R A;  5HPB A;  5HSU A;  3NZC X;  2W9H A;  4DPD A;  3UM5 A;  1DYH A;  3I3R A;  1M79 A;  2QK8 A;  3FYW X;  4LAH X;  1RA3 A;  3QLZ A;  1RX6 A;  3I8A X;  2HM9 A;  1DAJ A;  2W3A A;  5ECC A;  1E26 A;  1RA9 A;  4QHV A;  3F0Q X;  4KJJ A;  4KLX A;  3SQY X;  1U72 A;  1VDR A;  3NZA X;  1HFQ A;  1DDS A;  3SRR X;  2BLC A;  1OHK A;  2BLB A;  5HF0 X;  1QZF A;  4CD2 A;  2KGK A;  3LG4 A;  3TQB A;  1JOL A;  1DRA A;  4QLE A;  2ITH A;  2D5N A;  3DAT A;  4PTJ A;  1RX2 A;  3EEK A;  3QLW A;  1DF7 A;  1S3V A;  4X5J A;  3CSE A;  1M7A A;  2FZH A;  4GH8 A;  4HOE A;  4HA9 A;  3CD2 A;  3FYV X;  3F0S X;  3HJ3 A;  3NZ9 X;  4LAE X;  4OR7 A;  1BZF A;  5U27 A;  3S9U A;  3DRC A;  1PD8 A;  1IA1 A;  4KY4 A;  1DR4 A;  3F0U X;  3FRD X;  1J3J A;  3GHW A;  3FQF A;  3F0V X;  1CD2 A;  2CIG A;  3IRM A;  3NTZ A;  3NRR A;  3CL9 A;  1DYR A;  3KFY A;  1DR1 A;  5JG0 X;  4M6K A;  4ELB A;  3SGY A;  5EAJ A;  6DFR A;  2L28 A;  1IA4 A;  4I13 A;  4OSG A;  2W9S A;  2W3V A;  3DL5 A;  3JWM A;  3GI2 A;  4M7U A;  3DL6 A;  3FY9 X;  3KJR A;  5DXV A;  1DG8 A;  2W3W A;  4RGC A;  1DIU A;  1RF7 A;  1DG7 A;  4M7V A;  3FQC A;  1RX4 A;  1ZDR A;  3JW3 A;  4G95 A;  4QLF A;  4PSY A;  2OIP A;  1JOM A;  1DYI A;  2ANO A;  1DRH A;  4G3M A;  3RO9 A;  1S3W A;  1J3K A;  3QLR A;  3NXV A;  4XE6 X;  2W9T A;  3SA2 A;  1KLK A;  5E8Q A;  4PST A;  3IX9 A;  3KY8 A;  1MVS A;  3DG8 A;  1HFP A;  3F91 A;  3QYL A;  1DR7 A;  1DDR A;  1J3I A;  4ELH A;  2C2T A;  7DFR A;  3HBB A;  1KMS A;  3K45 A;  4KAK A;  1PD9 A;  1DG5 A;  3R33 A;  1TDR A;  3SRS X;  4Q0E A;  3FL8 A;  1SEJ A;  3D84 X;  3KGY A;  1AI9 A;  2P4G A;  4H95 A;  4KD7 A;  2XW7 A;  4FHB A;  4DDR A;  3UM6 A;  2D0K A;  3JWF A;  3NXX A;  3NZD A;  4HOG A;  3FRF X;  1KMV A;  4ECK A;  4LEK X;  3FQ0 A;  4XEC X;  2W3M A;  4FGG A;  4DFR A;  3IRN A;  1DHI A;  4M6J A;  1DIS A;  4KL9 A;  2HQP A;  4DP3 A;  1IA3 A;  3DGA A;  3OCH A;  3K74 A;  3Q1H A;  3F0B X;  1LUD A;  4KY8 A;  1IA2 A;  1DR2 A;  4P3Q A;  3JVX A;  3FRA X;  2JYB A;  1CZ3 A;  5HT4 A;  3EEL A;  3M09 A;  3FY8 X;  1RD7 A;  5HF2 X;  3DAU A;  1LY3 A;  4HOF A;  3NU0 A;  1VJ3 A;  4QI9 A;  1YHO A;  3F8Y A;  3TQ9 A;  2DRC A;  5HVE A;  3K47 A;  3FQV A;  4XRB A;  2LF1 A;  3D80 A;  1HFR A;  1S3U A;  3JW5 A;  4QLG A;  4KYA A;  1DYJ A;  2BL9 A;  1DLS A;  4LAG X;  1RX7 A;  1DRE A;  3QYO A;  3QLS A;  3JWK A;  2O7P A;  2H2Q A;  3RG9 A;  3FRB X;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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