2ANOA

Crystal structure of e.coli dihydrofolate reductase in complex with nadph and the inhibitor ms-sh08-17
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A 2.13 A Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 43
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2005-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 2anoA00
1IA3A 3F0SX 4KJKA 1AOEA 2CD2A 3IROA 1U72A 1DYRA 3NZ9X 1M7AA 2OIPA 3NXVA 5DFRA 2HM9A 3KFYA 3QL0A 1D1GA 3INVA 4KM2A 5HSRA 1DR2A 2W3MA 2DRCA 3RO9A 3QG2A 3I3RA 1DDRA 1RX6A 2W9HA 3FYWX 3FQCA 1JOMA 4LEKX 1PD8A 3GHCA 5HF0X 5HT4A 2LF1A 2D5NA 1DR5A 1RB3A 3NZCX 4KFJA 1QZFA 1S3WA 2B3ZA 4FHBA 3FL9A 4PTJA 1RX9A 2L28A 1RC4A 2FZJA 1DG5A 4Q0EA 1LUDA 5ECCA 3ZPCA 3SRQX 4IXGX 1RA2A 1S3YA 5HVEA 4HA7A 3QYOA 5ECXA 1RD7A 1RX5A 2HQPA 3SAIA 5HF2X 1IA2A 4KD7A 3R33A 1HFRA 4QHVA 4EIGA 3EEKA 1DHFA 4KJJA 5HPBA 3SA1A 1MVTA 4NX6A 4H96A 2CIGA 3GHVA 3QYLA 1DF7A 2BLAA 4PDJA 4OR7A 4GH8A 3RG9A 4G3MA 4EJ1A 3QLYA 5U27A 3I8AX 3FY9X 3FQFA 5HT5A 2JYBA 3FQOA 2OBCA 3TQAA 1DLRA 4XE6X 1DREA 3K45A 4CD2A 7DFRA 3DFRA 4KY4A 4H98A 3QLZA 4XT5A 2KGKA 4QJCA 3DGAA 5HI6A 4P3RA 5HUIA 1RX2A 4M7VA 1DHJA 4H95A 1KMVA 4RGCA 1RX1A 3FRBX 4P66A 3SRRX 4QJZD 4DFRA 3N0HA 1BZFA 1RA9A 1U71A 2C2SA 3GHWA 4TU5X 1DHIA 1E26A 1MVSA 3F0QX 2C2TA 3KJSA 5E8QA 4KLXA 1DYIA 2W3WA 1RA8A 1J3KA 3FYVX 3QLXA 4XT6A 3CD2A 3E0BA 1AO8A 4ECKA 1IA4A 4EILA 3IA4A 3NZ6X 1DG7A 3M08A 1RX8A 4XT7A 4Q0DA 3NXYA 4KJLA 3F91A 4HOGA 1S3UA 4I13A 3NXRA 4ELFA 2ZZAA 3NXXA 3IRMA 4M6KA 4X5IA 5DXVA 4ELHA 1KMSA 1VJ3A 3S7AA 3EIGA 3UM8A 2ITHA 4FGGA 4HA9A 2D0KA 1DDSA 5JG0X 1DR7A 3FY8X 2ANOA 3EEJA 1RX3A 3NXOA 2FZIA 5EAJA 5HQZA 5HVBA 2W3AA 3IRNA 3K74A 1DRHA 4IXFX 1LY4A 1YHOA 3JWCA 4EIZA 4KAKA 4OSGA 8DFRA 3K2HA 3UM5A 1J3IA 3SRSX 3F8YA 5HQYA 3QGTA 1RF7A 3FS6A 4LAHX 6DFRA 2BLCA 3NZBX 3DATA 1DR6A 5HSUA 1HFPA 1DRBA 4KM0A 3TD8A 2O7PA 1RH3A 4G95A 1CD2A 4X5JA 4ELEA 4FGHA 1PDBA 1DLSA 3FRFX 3FQ0A 3Q1HA 1J3JA 4DPDA 1DIUA 3GI2A 4M2XA 4Q67A 4X5FA 3CSEA 1OHKA 3HJ3A 1DISA 3FQVA 1RE7A 3JWFA 3OAFA 2DHFA 4NX7A 4M6LA 3SRWX 3KGYA 2INQA 4DDRA 1PD9A 2HXVA 3NZDA 3L3RA 4XT8A 3D80A 1BOZA 3QL3A 2GD9A 2QK8A 1M79A 4QLFA 4QI9A 3SH2A 4PSTA 4H97A 1DYJA 3FQZA 3ROAA 2G6VA 3F0XX 5CC9A 1LY3A 1RB2A 1DR4A 1KLKA 3D84X 3KJRA 3HBBA 3FREX 1RA3A 4P3QA 2W3VA 3FRDX 3VCOA 3DRCA 3NZAX 1RG7A 4KEBA 3F0BX 4KL9A 4HOEA 4X5HA 5CCCA 1TDRA 1JOLA 5JA3A 1RX7A 4XECX 3TQ9A 4ELBA 1AI9A 1S3VA 3OCHA 4KY8A 1DRAA 2FZHA 4XT4A 3IX9A 3UM6A 2W3BA 4I1NA 1U70A 3NRRA 2XW7A 2BLBA 3F0VX 1DRFA 5FDAA 1OHJA 4G8ZX 4M6JA 5U26A 4LAEX 2P4GA 4Q6AA 3QLSA 4DP3A 4PSSA 3CL9A 3JW5A 3FRAX 3JWMA 3QLRA 1HFQA 4LAGX 3TQ8A 2H2QA 3SQYX 3JTWA 4DPHA 4X5GA 3NU0A 3CLBA 2AZNA 4QLEA 1SEJA 3SRUX 4PSYA 3F8ZA 3JSUA 4KBNA 1DYHA 3SA2A 1JUVA 3NTZA 3EX8A 4HOFA 4KNEA 3EEMA 3F0UX 3JVXA 3LG4A 4KYAA 2W9TA 2W9SA 3DAUA 3JWKA 3ZPGA 1DG8A 1DR3A 3K47A 3TQBA 2W9GA 1DAJA 3M09A 1CZ3A 2ANQA 3DL5A 3QFXA 1ZDRA 3NXTA 4P68A 1DR1A 3S3VA 4ELGA 3EELA 3DL6A 3IA5A 3S9UA 4XRBA 3GYFA 1RA1A 4PTHA 1VDRA 1RX4A 4QLGA 3QLWA 1M78A 3SR5X 1IA1A 3FL8A 4IXED 3KY8A 4M7UA 3DG8A 2BL9A 3SGYA 3JW3A
chains in the Genus database with same CATH superfamily
1IA3A 3F0SX 4KJKA 1AOEA 2CD2A 3IROA 1U72A 1DYRA 3NZ9X 1M7AA 2OIPA 3NXVA 5DFRA 2HM9A 3KFYA 3QL0A 1D1GA 3INVA 4KM2A 5HSRA 1DR2A 2W3MA 2DRCA 3RO9A 3QG2A 3I3RA 1DDRA 1RX6A 2W9HA 3FYWX 3FQCA 1JOMA 4LEKX 1PD8A 3GHCA 5HF0X 5HT4A 2LF1A 2D5NA 1DR5A 1RB3A 3NZCX 4KFJA 1QZFA 1S3WA 2B3ZA 4FHBA 3FL9A 4PTJA 1RX9A 2L28A 1RC4A 2FZJA 1DG5A 4Q0EA 1LUDA 5ECCA 3ZPCA 3SRQX 4IXGX 1RA2A 1S3YA 5HVEA 4HA7A 3QYOA 5ECXA 1RD7A 1RX5A 2HQPA 3SAIA 5HF2X 1IA2A 4KD7A 3R33A 1HFRA 4QHVA 4EIGA 3EEKA 1DHFA 4KJJA 5HPBA 3SA1A 1MVTA 4NX6A 4H96A 2CIGA 3GHVA 3QYLA 1DF7A 2BLAA 4PDJA 4OR7A 4GH8A 3RG9A 4G3MA 4EJ1A 3QLYA 5U27A 3I8AX 3FY9X 3FQFA 5HT5A 2JYBA 3FQOA 2OBCA 3TQAA 1DLRA 4XE6X 1DREA 3K45A 4CD2A 7DFRA 3DFRA 4KY4A 4H98A 3QLZA 4XT5A 2KGKA 4QJCA 3DGAA 5HI6A 4P3RA 5HUIA 1RX2A 4M7VA 1DHJA 4H95A 1KMVA 4RGCA 1RX1A 3FRBX 4P66A 3SRRX 4QJZD 4DFRA 3N0HA 1BZFA 1RA9A 1U71A 2C2SA 3GHWA 4TU5X 1DHIA 1E26A 1MVSA 3F0QX 2C2TA 3KJSA 5E8QA 4KLXA 1DYIA 2W3WA 1RA8A 1J3KA 3FYVX 3QLXA 4XT6A 3CD2A 3E0BA 1AO8A 4ECKA 1IA4A 4EILA 3IA4A 3NZ6X 1DG7A 3M08A 1RX8A 4XT7A 4Q0DA 3NXYA 4KJLA 3F91A 4HOGA 1S3UA 4I13A 3NXRA 4ELFA 2ZZAA 3NXXA 3IRMA 4M6KA 4X5IA 5DXVA 4ELHA 1KMSA 1VJ3A 3S7AA 3EIGA 3UM8A 2ITHA 4FGGA 4HA9A 2D0KA 1DDSA 5JG0X 1DR7A 3FY8X 2ANOA 3EEJA 1RX3A 3NXOA 2FZIA 5EAJA 5HQZA 5HVBA 2W3AA 3IRNA 3K74A 1DRHA 4IXFX 1LY4A 1YHOA 3JWCA 4EIZA 4KAKA 4OSGA 8DFRA 3K2HA 3UM5A 1J3IA 3SRSX 3F8YA 5HQYA 3QGTA 1RF7A 3FS6A 4LAHX 6DFRA 2BLCA 3NZBX 3DATA 1DR6A 5HSUA 1HFPA 1DRBA 4KM0A 3TD8A 2O7PA 1RH3A 4G95A 1CD2A 4X5JA 4ELEA 4FGHA 1PDBA 1DLSA 3FRFX 3FQ0A 3Q1HA 1J3JA 4DPDA 1DIUA 3GI2A 4M2XA 4Q67A 4X5FA 3CSEA 1OHKA 3HJ3A 1DISA 3FQVA 1RE7A 3JWFA 3OAFA 2DHFA 4NX7A 4M6LA 3SRWX 3KGYA 2INQA 4DDRA 1PD9A 2HXVA 3NZDA 3L3RA 4XT8A 3D80A 1BOZA 3QL3A 2GD9A 2QK8A 1M79A 4QLFA 4QI9A 3SH2A 4PSTA 4H97A 1DYJA 3FQZA 3ROAA 2G6VA 3F0XX 5CC9A 1LY3A 1RB2A 1DR4A 1KLKA 3D84X 3KJRA 3HBBA 3FREX 1RA3A 4P3QA 2W3VA 3FRDX 3VCOA 3DRCA 3NZAX 1RG7A 4KEBA 3F0BX 4KL9A 4HOEA 4X5HA 5CCCA 1TDRA 1JOLA 5JA3A 1RX7A 4XECX 3TQ9A 4ELBA 1AI9A 1S3VA 3OCHA 4KY8A 1DRAA 2FZHA 4XT4A 3IX9A 3UM6A 2W3BA 4I1NA 1U70A 3NRRA 2XW7A 2BLBA 3F0VX 1DRFA 5FDAA 1OHJA 4G8ZX 4M6JA 5U26A 4LAEX 2P4GA 4Q6AA 3QLSA 4DP3A 4PSSA 3CL9A 3JW5A 3FRAX 3JWMA 3QLRA 1HFQA 4LAGX 3TQ8A 2H2QA 3SQYX 3JTWA 4DPHA 4X5GA 3NU0A 3CLBA 2AZNA 4QLEA 1SEJA 3SRUX 4PSYA 3F8ZA 3JSUA 4KBNA 1DYHA 3SA2A 1JUVA 3NTZA 3EX8A 4HOFA 4KNEA 3EEMA 3F0UX 3JVXA 3LG4A 4KYAA 2W9TA 2W9SA 3DAUA 3JWKA 3ZPGA 1DG8A 1DR3A 3K47A 3TQBA 2W9GA 1DAJA 3M09A 1CZ3A 2ANQA 3DL5A 3QFXA 1ZDRA 3NXTA 4P68A 1DR1A 3S3VA 4ELGA 3EELA 3DL6A 3IA5A 3S9UA 4XRBA 3GYFA 1RA1A 4PTHA 1VDRA 1RX4A 4QLGA 3QLWA 1M78A 3SR5X 1IA1A 3FL8A 4IXED 3KY8A 4M7UA 3DG8A 2BL9A 3SGYA 3JW3A
chains in the Genus database with same CATH topology
1IA3A 3F0SX 4KJKA 1AOEA 2CD2A 3IROA 1U72A 1DYRA 3NZ9X 1M7AA 2OIPA 3NXVA 5DFRA 2HM9A 3KFYA 3QL0A 1D1GA 3INVA 4KM2A 5HSRA 1DR2A 2W3MA 2DRCA 3RO9A 3QG2A 3I3RA 1DDRA 1RX6A 2W9HA 3FYWX 3FQCA 1JOMA 4LEKX 1PD8A 3GHCA 5HF0X 5HT4A 2LF1A 2D5NA 1DR5A 1RB3A 3NZCX 4KFJA 1QZFA 1S3WA 2B3ZA 4FHBA 3FL9A 4PTJA 1RX9A 2L28A 1RC4A 2FZJA 1DG5A 4Q0EA 1LUDA 5ECCA 3ZPCA 3SRQX 4IXGX 1RA2A 1S3YA 5HVEA 4HA7A 3QYOA 5ECXA 1RD7A 1RX5A 2HQPA 3SAIA 5HF2X 1IA2A 4KD7A 3R33A 1HFRA 4QHVA 4EIGA 3EEKA 1DHFA 4KJJA 5HPBA 3SA1A 1MVTA 4NX6A 4H96A 2CIGA 3GHVA 3QYLA 1DF7A 2BLAA 4PDJA 4OR7A 4GH8A 3RG9A 4G3MA 4EJ1A 3QLYA 5U27A 3I8AX 3FY9X 3FQFA 5HT5A 2JYBA 3FQOA 2OBCA 3TQAA 1DLRA 4XE6X 1DREA 3K45A 4CD2A 7DFRA 3DFRA 4KY4A 4H98A 3QLZA 4XT5A 2KGKA 4QJCA 3DGAA 5HI6A 4P3RA 5HUIA 1RX2A 4M7VA 1DHJA 4H95A 1KMVA 4RGCA 1RX1A 3FRBX 4P66A 3SRRX 4QJZD 4DFRA 3N0HA 1BZFA 1RA9A 1U71A 2C2SA 3GHWA 4TU5X 1DHIA 1E26A 1MVSA 3F0QX 2C2TA 3KJSA 5E8QA 4KLXA 1DYIA 2W3WA 1RA8A 1J3KA 3FYVX 3QLXA 4XT6A 3CD2A 3E0BA 1AO8A 4ECKA 1IA4A 4EILA 3IA4A 3NZ6X 1DG7A 3M08A 1RX8A 4XT7A 4Q0DA 3NXYA 4KJLA 3F91A 4HOGA 1S3UA 4I13A 3NXRA 4ELFA 2ZZAA 3NXXA 3IRMA 4M6KA 4X5IA 5DXVA 4ELHA 1KMSA 1VJ3A 3S7AA 3EIGA 3UM8A 2ITHA 4FGGA 4HA9A 2D0KA 1DDSA 5JG0X 1DR7A 3FY8X 2ANOA 3EEJA 1RX3A 3NXOA 2FZIA 5EAJA 5HQZA 5HVBA 2W3AA 3IRNA 3K74A 1DRHA 4IXFX 1LY4A 1YHOA 3JWCA 4EIZA 4KAKA 4OSGA 8DFRA 3K2HA 3UM5A 1J3IA 3SRSX 3F8YA 5HQYA 3QGTA 1RF7A 3FS6A 4LAHX 6DFRA 2BLCA 3NZBX 3DATA 1DR6A 5HSUA 1HFPA 1DRBA 4KM0A 3TD8A 2O7PA 1RH3A 4G95A 1CD2A 4X5JA 4ELEA 4FGHA 1PDBA 1DLSA 3FRFX 3FQ0A 3Q1HA 1J3JA 4DPDA 1DIUA 3GI2A 4M2XA 4Q67A 4X5FA 3CSEA 1OHKA 3HJ3A 1DISA 3FQVA 1RE7A 3JWFA 3OAFA 2DHFA 4NX7A 4M6LA 3SRWX 3KGYA 2INQA 4DDRA 1PD9A 2HXVA 3NZDA 3L3RA 4XT8A 3D80A 1BOZA 3QL3A 2GD9A 2QK8A 1M79A 4QLFA 4QI9A 3SH2A 4PSTA 4H97A 1DYJA 3FQZA 3ROAA 2G6VA 3F0XX 5CC9A 1LY3A 1RB2A 1DR4A 1KLKA 3D84X 3KJRA 3HBBA 3FREX 1RA3A 4P3QA 2W3VA 3FRDX 3VCOA 3DRCA 3NZAX 1RG7A 4KEBA 3F0BX 4KL9A 4HOEA 4X5HA 5CCCA 1TDRA 1JOLA 5JA3A 1RX7A 4XECX 3TQ9A 4ELBA 1AI9A 1S3VA 3OCHA 4KY8A 1DRAA 2FZHA 4XT4A 3IX9A 3UM6A 2W3BA 4I1NA 1U70A 3NRRA 2XW7A 2BLBA 3F0VX 1DRFA 5FDAA 1OHJA 4G8ZX 4M6JA 5U26A 4LAEX 2P4GA 4Q6AA 3QLSA 4DP3A 4PSSA 3CL9A 3JW5A 3FRAX 3JWMA 3QLRA 1HFQA 4LAGX 3TQ8A 2H2QA 3SQYX 3JTWA 4DPHA 4X5GA 3NU0A 3CLBA 2AZNA 4QLEA 1SEJA 3SRUX 4PSYA 3F8ZA 3JSUA 4KBNA 1DYHA 3SA2A 1JUVA 3NTZA 3EX8A 4HOFA 4KNEA 3EEMA 3F0UX 3JVXA 3LG4A 4KYAA 2W9TA 2W9SA 3DAUA 3JWKA 3ZPGA 1DG8A 1DR3A 3K47A 3TQBA 2W9GA 1DAJA 3M09A 1CZ3A 2ANQA 3DL5A 3QFXA 1ZDRA 3NXTA 4P68A 1DR1A 3S3VA 4ELGA 3EELA 3DL6A 3IA5A 3S9UA 4XRBA 3GYFA 1RA1A 4PTHA 1VDRA 1RX4A 4QLGA 3QLWA 1M78A 3SR5X 1IA1A 3FL8A 4IXED 3KY8A 4M7UA 3DG8A 2BL9A 3SGYA 3JW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IA3 A;  3F0S X;  4KJK A;  1AOE A;  2CD2 A;  3IRO A;  1U72 A;  1DYR A;  3NZ9 X;  1M7A A;  2OIP A;  3NXV A;  5DFR A;  2HM9 A;  3KFY A;  3QL0 A;  1D1G A;  3INV A;  4KM2 A;  5HSR A;  1DR2 A;  2W3M A;  2DRC A;  3RO9 A;  3QG2 A;  3I3R A;  1DDR A;  1RX6 A;  2W9H A;  3FYW X;  3FQC A;  1JOM A;  4LEK X;  1PD8 A;  3GHC A;  5HF0 X;  5HT4 A;  2LF1 A;  2D5N A;  1DR5 A;  1RB3 A;  3NZC X;  4KFJ A;  1QZF A;  1S3W A;  2B3Z A;  4FHB A;  3FL9 A;  4PTJ A;  1RX9 A;  2L28 A;  1RC4 A;  2FZJ A;  1DG5 A;  4Q0E A;  1LUD A;  5ECC A;  3ZPC A;  3SRQ X;  4IXG X;  1RA2 A;  1S3Y A;  5HVE A;  4HA7 A;  3QYO A;  5ECX A;  1RD7 A;  1RX5 A;  2HQP A;  3SAI A;  5HF2 X;  1IA2 A;  4KD7 A;  3R33 A;  1HFR A;  4QHV A;  4EIG A;  3EEK A;  1DHF A;  4KJJ A;  5HPB A;  3SA1 A;  1MVT A;  4NX6 A;  4H96 A;  2CIG A;  3GHV A;  3QYL A;  1DF7 A;  2BLA A;  4PDJ A;  4OR7 A;  4GH8 A;  3RG9 A;  4G3M A;  4EJ1 A;  3QLY A;  5U27 A;  3I8A X;  3FY9 X;  3FQF A;  5HT5 A;  2JYB A;  3FQO A;  2OBC A;  3TQA A;  1DLR A;  4XE6 X;  1DRE A;  3K45 A;  4CD2 A;  7DFR A;  3DFR A;  4KY4 A;  4H98 A;  3QLZ A;  4XT5 A;  2KGK A;  4QJC A;  3DGA A;  5HI6 A;  4P3R A;  5HUI A;  1RX2 A;  4M7V A;  1DHJ A;  4H95 A;  1KMV A;  4RGC A;  1RX1 A;  3FRB X;  4P66 A;  3SRR X;  4QJZ D;  4DFR A;  3N0H A;  1BZF A;  1RA9 A;  1U71 A;  2C2S A;  3GHW A;  4TU5 X;  1DHI A;  1E26 A;  1MVS A;  3F0Q X;  2C2T A;  3KJS A;  5E8Q A;  4KLX A;  1DYI A;  2W3W A;  1RA8 A;  1J3K A;  3FYV X;  3QLX A;  4XT6 A;  3CD2 A;  3E0B A;  1AO8 A;  4ECK A;  1IA4 A;  4EIL A;  3IA4 A;  3NZ6 X;  1DG7 A;  3M08 A;  1RX8 A;  4XT7 A;  4Q0D A;  3NXY A;  4KJL A;  3F91 A;  4HOG A;  1S3U A;  4I13 A;  3NXR A;  4ELF A;  2ZZA A;  3NXX A;  3IRM A;  4M6K A;  4X5I A;  5DXV A;  4ELH A;  1KMS A;  1VJ3 A;  3S7A A;  3EIG A;  3UM8 A;  2ITH A;  4FGG A;  4HA9 A;  2D0K A;  1DDS A;  5JG0 X;  1DR7 A;  3FY8 X;  2ANO A;  3EEJ A;  1RX3 A;  3NXO A;  2FZI A;  5EAJ A;  5HQZ A;  5HVB A;  2W3A A;  3IRN A;  3K74 A;  1DRH A;  4IXF X;  1LY4 A;  1YHO A;  3JWC A;  4EIZ A;  4KAK A;  4OSG A;  8DFR A;  3K2H A;  3UM5 A;  1J3I A;  3SRS X;  3F8Y A;  5HQY A;  3QGT A;  1RF7 A;  3FS6 A;  4LAH X;  6DFR A;  2BLC A;  3NZB X;  3DAT A;  1DR6 A;  5HSU A;  1HFP A;  1DRB A;  4KM0 A;  3TD8 A;  2O7P A;  1RH3 A;  4G95 A;  1CD2 A;  4X5J A;  4ELE A;  4FGH A;  1PDB A;  1DLS A;  3FRF X;  3FQ0 A;  3Q1H A;  1J3J A;  4DPD A;  1DIU A;  3GI2 A;  4M2X A;  4Q67 A;  4X5F A;  3CSE A;  1OHK A;  3HJ3 A;  1DIS A;  3FQV A;  1RE7 A;  3JWF A;  3OAF A;  2DHF A;  4NX7 A;  4M6L A;  3SRW X;  3KGY A;  2INQ A;  4DDR A;  1PD9 A;  2HXV A;  3NZD A;  3L3R A;  4XT8 A;  3D80 A;  1BOZ A;  3QL3 A;  2GD9 A;  2QK8 A;  1M79 A;  4QLF A;  4QI9 A;  3SH2 A;  4PST A;  4H97 A;  1DYJ A;  3FQZ A;  3ROA A;  2G6V A;  3F0X X;  5CC9 A;  1LY3 A;  1RB2 A;  1DR4 A;  1KLK A;  3D84 X;  3KJR A;  3HBB A;  3FRE X;  1RA3 A;  4P3Q A;  2W3V A;  3FRD X;  3VCO A;  3DRC A;  3NZA X;  1RG7 A;  4KEB A;  3F0B X;  4KL9 A;  4HOE A;  4X5H A;  5CCC A;  1TDR A;  1JOL A;  5JA3 A;  1RX7 A;  4XEC X;  3TQ9 A;  4ELB A;  1AI9 A;  1S3V A;  3OCH A;  4KY8 A;  1DRA A;  2FZH A;  4XT4 A;  3IX9 A;  3UM6 A;  2W3B A;  4I1N A;  1U70 A;  3NRR A;  2XW7 A;  2BLB A;  3F0V X;  1DRF A;  5FDA A;  1OHJ A;  4G8Z X;  4M6J A;  5U26 A;  4LAE X;  2P4G A;  4Q6A A;  3QLS A;  4DP3 A;  4PSS A;  3CL9 A;  3JW5 A;  3FRA X;  3JWM A;  3QLR A;  1HFQ A;  4LAG X;  3TQ8 A;  2H2Q A;  3SQY X;  3JTW A;  4DPH A;  4X5G A;  3NU0 A;  3CLB A;  2AZN A;  4QLE A;  1SEJ A;  3SRU X;  4PSY A;  3F8Z A;  3JSU A;  4KBN A;  1DYH A;  3SA2 A;  1JUV A;  3NTZ A;  3EX8 A;  4HOF A;  4KNE A;  3EEM A;  3F0U X;  3JVX A;  3LG4 A;  4KYA A;  2W9T A;  2W9S A;  3DAU A;  3JWK A;  3ZPG A;  1DG8 A;  1DR3 A;  3K47 A;  3TQB A;  2W9G A;  1DAJ A;  3M09 A;  1CZ3 A;  2ANQ A;  3DL5 A;  3QFX A;  1ZDR A;  3NXT A;  4P68 A;  1DR1 A;  3S3V A;  4ELG A;  3EEL A;  3DL6 A;  3IA5 A;  3S9U A;  4XRB A;  3GYF A;  1RA1 A;  4PTH A;  1VDR A;  1RX4 A;  4QLG A;  3QLW A;  1M78 A;  3SR5 X;  1IA1 A;  3FL8 A;  4IXE D;  3KY8 A;  4M7U A;  3DG8 A;  2BL9 A;  3SGY A;  3JW3 A; 
#chains in the Genus database with same CATH topology
 1IA3 A;  3F0S X;  4KJK A;  1AOE A;  2CD2 A;  3IRO A;  1U72 A;  1DYR A;  3NZ9 X;  1M7A A;  2OIP A;  3NXV A;  5DFR A;  2HM9 A;  3KFY A;  3QL0 A;  1D1G A;  3INV A;  4KM2 A;  5HSR A;  1DR2 A;  2W3M A;  2DRC A;  3RO9 A;  3QG2 A;  3I3R A;  1DDR A;  1RX6 A;  2W9H A;  3FYW X;  3FQC A;  1JOM A;  4LEK X;  1PD8 A;  3GHC A;  5HF0 X;  5HT4 A;  2LF1 A;  2D5N A;  1DR5 A;  1RB3 A;  3NZC X;  4KFJ A;  1QZF A;  1S3W A;  2B3Z A;  4FHB A;  3FL9 A;  4PTJ A;  1RX9 A;  2L28 A;  1RC4 A;  2FZJ A;  1DG5 A;  4Q0E A;  1LUD A;  5ECC A;  3ZPC A;  3SRQ X;  4IXG X;  1RA2 A;  1S3Y A;  5HVE A;  4HA7 A;  3QYO A;  5ECX A;  1RD7 A;  1RX5 A;  2HQP A;  3SAI A;  5HF2 X;  1IA2 A;  4KD7 A;  3R33 A;  1HFR A;  4QHV A;  4EIG A;  3EEK A;  1DHF A;  4KJJ A;  5HPB A;  3SA1 A;  1MVT A;  4NX6 A;  4H96 A;  2CIG A;  3GHV A;  3QYL A;  1DF7 A;  2BLA A;  4PDJ A;  4OR7 A;  4GH8 A;  3RG9 A;  4G3M A;  4EJ1 A;  3QLY A;  5U27 A;  3I8A X;  3FY9 X;  3FQF A;  5HT5 A;  2JYB A;  3FQO A;  2OBC A;  3TQA A;  1DLR A;  4XE6 X;  1DRE A;  3K45 A;  4CD2 A;  7DFR A;  3DFR A;  4KY4 A;  4H98 A;  3QLZ A;  4XT5 A;  2KGK A;  4QJC A;  3DGA A;  5HI6 A;  4P3R A;  5HUI A;  1RX2 A;  4M7V A;  1DHJ A;  4H95 A;  1KMV A;  4RGC A;  1RX1 A;  3FRB X;  4P66 A;  3SRR X;  4QJZ D;  4DFR A;  3N0H A;  1BZF A;  1RA9 A;  1U71 A;  2C2S A;  3GHW A;  4TU5 X;  1DHI A;  1E26 A;  1MVS A;  3F0Q X;  2C2T A;  3KJS A;  5E8Q A;  4KLX A;  1DYI A;  2W3W A;  1RA8 A;  1J3K A;  3FYV X;  3QLX A;  4XT6 A;  3CD2 A;  3E0B A;  1AO8 A;  4ECK A;  1IA4 A;  4EIL A;  3IA4 A;  3NZ6 X;  1DG7 A;  3M08 A;  1RX8 A;  4XT7 A;  4Q0D A;  3NXY A;  4KJL A;  3F91 A;  4HOG A;  1S3U A;  4I13 A;  3NXR A;  4ELF A;  2ZZA A;  3NXX A;  3IRM A;  4M6K A;  4X5I A;  5DXV A;  4ELH A;  1KMS A;  1VJ3 A;  3S7A A;  3EIG A;  3UM8 A;  2ITH A;  4FGG A;  4HA9 A;  2D0K A;  1DDS A;  5JG0 X;  1DR7 A;  3FY8 X;  2ANO A;  3EEJ A;  1RX3 A;  3NXO A;  2FZI A;  5EAJ A;  5HQZ A;  5HVB A;  2W3A A;  3IRN A;  3K74 A;  1DRH A;  4IXF X;  1LY4 A;  1YHO A;  3JWC A;  4EIZ A;  4KAK A;  4OSG A;  8DFR A;  3K2H A;  3UM5 A;  1J3I A;  3SRS X;  3F8Y A;  5HQY A;  3QGT A;  1RF7 A;  3FS6 A;  4LAH X;  6DFR A;  2BLC A;  3NZB X;  3DAT A;  1DR6 A;  5HSU A;  1HFP A;  1DRB A;  4KM0 A;  3TD8 A;  2O7P A;  1RH3 A;  4G95 A;  1CD2 A;  4X5J A;  4ELE A;  4FGH A;  1PDB A;  1DLS A;  3FRF X;  3FQ0 A;  3Q1H A;  1J3J A;  4DPD A;  1DIU A;  3GI2 A;  4M2X A;  4Q67 A;  4X5F A;  3CSE A;  1OHK A;  3HJ3 A;  1DIS A;  3FQV A;  1RE7 A;  3JWF A;  3OAF A;  2DHF A;  4NX7 A;  4M6L A;  3SRW X;  3KGY A;  2INQ A;  4DDR A;  1PD9 A;  2HXV A;  3NZD A;  3L3R A;  4XT8 A;  3D80 A;  1BOZ A;  3QL3 A;  2GD9 A;  2QK8 A;  1M79 A;  4QLF A;  4QI9 A;  3SH2 A;  4PST A;  4H97 A;  1DYJ A;  3FQZ A;  3ROA A;  2G6V A;  3F0X X;  5CC9 A;  1LY3 A;  1RB2 A;  1DR4 A;  1KLK A;  3D84 X;  3KJR A;  3HBB A;  3FRE X;  1RA3 A;  4P3Q A;  2W3V A;  3FRD X;  3VCO A;  3DRC A;  3NZA X;  1RG7 A;  4KEB A;  3F0B X;  4KL9 A;  4HOE A;  4X5H A;  5CCC A;  1TDR A;  1JOL A;  5JA3 A;  1RX7 A;  4XEC X;  3TQ9 A;  4ELB A;  1AI9 A;  1S3V A;  3OCH A;  4KY8 A;  1DRA A;  2FZH A;  4XT4 A;  3IX9 A;  3UM6 A;  2W3B A;  4I1N A;  1U70 A;  3NRR A;  2XW7 A;  2BLB A;  3F0V X;  1DRF A;  5FDA A;  1OHJ A;  4G8Z X;  4M6J A;  5U26 A;  4LAE X;  2P4G A;  4Q6A A;  3QLS A;  4DP3 A;  4PSS A;  3CL9 A;  3JW5 A;  3FRA X;  3JWM A;  3QLR A;  1HFQ A;  4LAG X;  3TQ8 A;  2H2Q A;  3SQY X;  3JTW A;  4DPH A;  4X5G A;  3NU0 A;  3CLB A;  2AZN A;  4QLE A;  1SEJ A;  3SRU X;  4PSY A;  3F8Z A;  3JSU A;  4KBN A;  1DYH A;  3SA2 A;  1JUV A;  3NTZ A;  3EX8 A;  4HOF A;  4KNE A;  3EEM A;  3F0U X;  3JVX A;  3LG4 A;  4KYA A;  2W9T A;  2W9S A;  3DAU A;  3JWK A;  3ZPG A;  1DG8 A;  1DR3 A;  3K47 A;  3TQB A;  2W9G A;  1DAJ A;  3M09 A;  1CZ3 A;  2ANQ A;  3DL5 A;  3QFX A;  1ZDR A;  3NXT A;  4P68 A;  1DR1 A;  3S3V A;  4ELG A;  3EEL A;  3DL6 A;  3IA5 A;  3S9U A;  4XRB A;  3GYF A;  1RA1 A;  4PTH A;  1VDR A;  1RX4 A;  4QLG A;  3QLW A;  1M78 A;  3SR5 X;  1IA1 A;  3FL8 A;  4IXE D;  3KY8 A;  4M7U A;  3DG8 A;  2BL9 A;  3SGY A;  3JW3 A; 
#chains in the Genus database with same CATH homology
 1IA3 A;  3F0S X;  4KJK A;  1AOE A;  2CD2 A;  3IRO A;  1U72 A;  1DYR A;  3NZ9 X;  1M7A A;  2OIP A;  3NXV A;  5DFR A;  2HM9 A;  3KFY A;  3QL0 A;  1D1G A;  3INV A;  4KM2 A;  5HSR A;  1DR2 A;  2W3M A;  2DRC A;  3RO9 A;  3QG2 A;  3I3R A;  1DDR A;  1RX6 A;  2W9H A;  3FYW X;  3FQC A;  1JOM A;  4LEK X;  1PD8 A;  3GHC A;  5HF0 X;  5HT4 A;  2LF1 A;  2D5N A;  1DR5 A;  1RB3 A;  3NZC X;  4KFJ A;  1QZF A;  1S3W A;  2B3Z A;  4FHB A;  3FL9 A;  4PTJ A;  1RX9 A;  2L28 A;  1RC4 A;  2FZJ A;  1DG5 A;  4Q0E A;  1LUD A;  5ECC A;  3ZPC A;  3SRQ X;  4IXG X;  1RA2 A;  1S3Y A;  5HVE A;  4HA7 A;  3QYO A;  5ECX A;  1RD7 A;  1RX5 A;  2HQP A;  3SAI A;  5HF2 X;  1IA2 A;  4KD7 A;  3R33 A;  1HFR A;  4QHV A;  4EIG A;  3EEK A;  1DHF A;  4KJJ A;  5HPB A;  3SA1 A;  1MVT A;  4NX6 A;  4H96 A;  2CIG A;  3GHV A;  3QYL A;  1DF7 A;  2BLA A;  4PDJ A;  4OR7 A;  4GH8 A;  3RG9 A;  4G3M A;  4EJ1 A;  3QLY A;  5U27 A;  3I8A X;  3FY9 X;  3FQF A;  5HT5 A;  2JYB A;  3FQO A;  2OBC A;  3TQA A;  1DLR A;  4XE6 X;  1DRE A;  3K45 A;  4CD2 A;  7DFR A;  3DFR A;  4KY4 A;  4H98 A;  3QLZ A;  4XT5 A;  2KGK A;  4QJC A;  3DGA A;  5HI6 A;  4P3R A;  5HUI A;  1RX2 A;  4M7V A;  1DHJ A;  4H95 A;  1KMV A;  4RGC A;  1RX1 A;  3FRB X;  4P66 A;  3SRR X;  4QJZ D;  4DFR A;  3N0H A;  1BZF A;  1RA9 A;  1U71 A;  2C2S A;  3GHW A;  4TU5 X;  1DHI A;  1E26 A;  1MVS A;  3F0Q X;  2C2T A;  3KJS A;  5E8Q A;  4KLX A;  1DYI A;  2W3W A;  1RA8 A;  1J3K A;  3FYV X;  3QLX A;  4XT6 A;  3CD2 A;  3E0B A;  1AO8 A;  4ECK A;  1IA4 A;  4EIL A;  3IA4 A;  3NZ6 X;  1DG7 A;  3M08 A;  1RX8 A;  4XT7 A;  4Q0D A;  3NXY A;  4KJL A;  3F91 A;  4HOG A;  1S3U A;  4I13 A;  3NXR A;  4ELF A;  2ZZA A;  3NXX A;  3IRM A;  4M6K A;  4X5I A;  5DXV A;  4ELH A;  1KMS A;  1VJ3 A;  3S7A A;  3EIG A;  3UM8 A;  2ITH A;  4FGG A;  4HA9 A;  2D0K A;  1DDS A;  5JG0 X;  1DR7 A;  3FY8 X;  2ANO A;  3EEJ A;  1RX3 A;  3NXO A;  2FZI A;  5EAJ A;  5HQZ A;  5HVB A;  2W3A A;  3IRN A;  3K74 A;  1DRH A;  4IXF X;  1LY4 A;  1YHO A;  3JWC A;  4EIZ A;  4KAK A;  4OSG A;  8DFR A;  3K2H A;  3UM5 A;  1J3I A;  3SRS X;  3F8Y A;  5HQY A;  3QGT A;  1RF7 A;  3FS6 A;  4LAH X;  6DFR A;  2BLC A;  3NZB X;  3DAT A;  1DR6 A;  5HSU A;  1HFP A;  1DRB A;  4KM0 A;  3TD8 A;  2O7P A;  1RH3 A;  4G95 A;  1CD2 A;  4X5J A;  4ELE A;  4FGH A;  1PDB A;  1DLS A;  3FRF X;  3FQ0 A;  3Q1H A;  1J3J A;  4DPD A;  1DIU A;  3GI2 A;  4M2X A;  4Q67 A;  4X5F A;  3CSE A;  1OHK A;  3HJ3 A;  1DIS A;  3FQV A;  1RE7 A;  3JWF A;  3OAF A;  2DHF A;  4NX7 A;  4M6L A;  3SRW X;  3KGY A;  2INQ A;  4DDR A;  1PD9 A;  2HXV A;  3NZD A;  3L3R A;  4XT8 A;  3D80 A;  1BOZ A;  3QL3 A;  2GD9 A;  2QK8 A;  1M79 A;  4QLF A;  4QI9 A;  3SH2 A;  4PST A;  4H97 A;  1DYJ A;  3FQZ A;  3ROA A;  2G6V A;  3F0X X;  5CC9 A;  1LY3 A;  1RB2 A;  1DR4 A;  1KLK A;  3D84 X;  3KJR A;  3HBB A;  3FRE X;  1RA3 A;  4P3Q A;  2W3V A;  3FRD X;  3VCO A;  3DRC A;  3NZA X;  1RG7 A;  4KEB A;  3F0B X;  4KL9 A;  4HOE A;  4X5H A;  5CCC A;  1TDR A;  1JOL A;  5JA3 A;  1RX7 A;  4XEC X;  3TQ9 A;  4ELB A;  1AI9 A;  1S3V A;  3OCH A;  4KY8 A;  1DRA A;  2FZH A;  4XT4 A;  3IX9 A;  3UM6 A;  2W3B A;  4I1N A;  1U70 A;  3NRR A;  2XW7 A;  2BLB A;  3F0V X;  1DRF A;  5FDA A;  1OHJ A;  4G8Z X;  4M6J A;  5U26 A;  4LAE X;  2P4G A;  4Q6A A;  3QLS A;  4DP3 A;  4PSS A;  3CL9 A;  3JW5 A;  3FRA X;  3JWM A;  3QLR A;  1HFQ A;  4LAG X;  3TQ8 A;  2H2Q A;  3SQY X;  3JTW A;  4DPH A;  4X5G A;  3NU0 A;  3CLB A;  2AZN A;  4QLE A;  1SEJ A;  3SRU X;  4PSY A;  3F8Z A;  3JSU A;  4KBN A;  1DYH A;  3SA2 A;  1JUV A;  3NTZ A;  3EX8 A;  4HOF A;  4KNE A;  3EEM A;  3F0U X;  3JVX A;  3LG4 A;  4KYA A;  2W9T A;  2W9S A;  3DAU A;  3JWK A;  3ZPG A;  1DG8 A;  1DR3 A;  3K47 A;  3TQB A;  2W9G A;  1DAJ A;  3M09 A;  1CZ3 A;  2ANQ A;  3DL5 A;  3QFX A;  1ZDR A;  3NXT A;  4P68 A;  1DR1 A;  3S3V A;  4ELG A;  3EEL A;  3DL6 A;  3IA5 A;  3S9U A;  4XRB A;  3GYF A;  1RA1 A;  4PTH A;  1VDR A;  1RX4 A;  4QLG A;  3QLW A;  1M78 A;  3SR5 X;  1IA1 A;  3FL8 A;  4IXE D;  3KY8 A;  4M7U A;  3DG8 A;  2BL9 A;  3SGY A;  3JW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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