2CD2A

Ligand induced conformational changes in the crystal structures of pneumocystis carinii dihydrofolate reductase complexes with folate and nadp+
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
206
structure length
206
Chain Sequence
MNQQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQFRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Pneumocystis carinii
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 57
structure length 206
sequence length 206
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1999-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 2cd2A00
1U71A 4DFRA 2KGKA 5CCCA 1DRFA 1LUDA 3SAIA 4XT5A 1U70A 3M08A 4KY8A 1DR3A 3FQZA 1DG7A 3IRNA 1PD8A 3JSUA 5ECXA 3N0HA 2AZNA 2ANQA 1KLKA 3NXYA 1AO8A 4KNEA 1DR5A 5HQYA 1MVSA 3GYFA 1E26A 2W9GA 4XT6A 3FQCA 2GD9A 3NZAX 3NZ9X 2ITHA 3QLYA 3KJSA 1CZ3A 3CLBA 4PDJA 5FDAA 3FRDX 4IXFX 1JUVA 7DFRA 4LAGX 3KY8A 3NXXA 3SRQX 5DFRA 1HFRA 3QFXA 3FL9A 1DR1A 1U72A 1S3VA 1OHJA 4XRBA 3DFRA 2H2QA 1OHKA 1RB3A 3D84X 3M09A 1JOMA 1DR7A 3JWKA 3UM5A 3IRMA 1IA2A 3IROA 3D80A 4DP3A 4QJZD 3FRFX 3S9UA 1BOZA 5JG0X 4ELGA 1RA8A 3DRCA 4RGCA 4HOFA 3E0BA 4G95A 1SEJA 5HI6A 3F91A 4PSTA 3JWCA 6DFRA 2L28A 3DG8A 4XT4A 4M7UA 3NXOA 1DRAA 3TQ9A 1ZDRA 1RH3A 3FQFA 3UM8A 2JYBA 2HQPA 3K45A 3TQAA 4KLXA 2ZZAA 5HPBA 3JWMA 3KGYA 1RX9A 1D1GA 4HOEA 4KL9A 1AOEA 4ELFA 2C2SA 3F8ZA 1DRBA 1S3YA 4KJLA 3FQVA 3FS6A 3HBBA 3QLWA 4X5IA 1RX1A 4LAEX 4EIZA 3KFYA 1DISA 3QG2A 5EAJA 3VCOA 3F0XX 2FZHA 3FQ0A 3TQ8A 2DRCA 1IA3A 8DFRA 3FL8A 3GI2A 4KBNA 1DYRA 1DG8A 1RB2A 4LEKX 4KM2A 1S3WA 3QYLA 3F8YA 3K47A 4KJJA 3SGYA 1HFPA 1DYHA 1JOLA 3QGTA 3QLXA 1DR6A 1M7AA 4EILA 1CD2A 2W3VA 4X5FA 1RE7A 3NXRA 3RO9A 3QLSA 4Q6AA 4QLGA 5CC9A 1DLSA 1DREA 4KY4A 3F0SX 3EEMA 3SRRX 5HF2X 2DHFA 4XT7A 3NRRA 3ROAA 1DYJA 5HF0X 1RX3A 1DR4A 3DGAA 1RX7A 3DATA 3SA2A 4M2XA 2CD2A 3RG9A 2HM9A 2W3AA 4P66A 4I13A 1RX5A 4KFJA 1DHJA 4HA7A 4ELHA 4PSYA 4XECX 1KMSA 3JW5A 3FY9X 4FHBA 1RX4A 3NXVA 1IA4A 4H97A 3NZCX 1PD9A 4GH8A 1RA3A 3HJ3A 4FGGA 3K74A 4P3QA 1DYIA 1YHOA 1RX2A 2W3BA 1RF7A 3ZPGA 1DRHA 3CD2A 4Q67A 2INQA 2CIGA 2W9TA 1LY4A 2W9HA 4H95A 4X5JA 3IA5A 2BLBA 3S7AA 2B3ZA 3TQBA 4KD7A 1RA9A 1DG5A 4IXGX 3INVA 2FZJA 4I1NA 4LAHX 3JVXA 4ELEA 4M6LA 4G8ZX 4HA9A 3DAUA 2HXVA 1J3IA 2QK8A 1HFQA 3QLZA 3FYVX 4ELBA 2LF1A 1M79A 1AI9A 3EELA 1RA2A 1MVTA 1DAJA 3IA4A 3FRAX 3CL9A 3SQYX 3F0BX 2OIPA 3SA1A 1QZFA 4QJCA 3TD8A 4Q0EA 2FZIA 3ZPCA 4H96A 4XE6X 4Q0DA 3QYOA 3SRUX 3F0QX 2P4GA 3EEKA 1J3JA 1DIUA 2W9SA 5DXVA 3QLRA 4PTHA 4EJ1A 1RD7A 1RC4A 4DPHA 3NZBX 5HSUA 4KEBA 4QLEA 1DHFA 4NX7A 4XT8A 1DR2A 3SR5X 4M6JA 3DL5A 4P68A 3KJRA 4P3RA 3EEJA 3OCHA 2D5NA 4QHVA 4OR7A 2XW7A 3FREX 3FQOA 4QLFA 4ECKA 1J3KA 3NTZA 1M78A 3SRWX 2W3MA 3NU0A 3NZDA 4DDRA 3FRBX 4HOGA 3S3VA 4KJKA 2C2TA 2G6VA 4IXED 4OSGA 1VDRA 1RA1A 5U26A 4FGHA 3F0VX 1BZFA 1LY3A 3GHWA 3SRSX 3QL3A 1RX6A 4X5GA 4CD2A 3GHCA 1KMVA 2D0KA 5HSRA 1DDSA 4M6KA 4H98A 3F0UX 5HQZA 3NZ6X 5HT4A 5HVBA 3K2HA 3OAFA 3GHVA 3NXTA 3FY8X 4KAKA 2BLAA 3JW3A 2BL9A 1DDRA 3JTWA 5JA3A 5HT5A 5E8QA 5U27A 4PTJA 1VJ3A 1RG7A 3FYWX 4PSSA 1IA1A 3DL6A 1TDRA 3EX8A 4KM0A 1DHIA 4G3MA 2W3WA 4TU5X 1S3UA 4NX6A 2BLCA 2O7PA 4X5HA 3R33A 4DPDA 5ECCA 3SH2A 2ANOA 3L3RA 5HVEA 3JWFA 3I8AX 1DLRA 1DF7A 3LG4A 4EIGA 3EIGA 3QL0A 3Q1HA 5HUIA 2OBCA 3UM6A 3I3RA 4M7VA 4QI9A 4KYAA 3CSEA 1RX8A 1PDBA 3IX9A
chains in the Genus database with same CATH superfamily
1U71A 4DFRA 2KGKA 5CCCA 1DRFA 1LUDA 3SAIA 4XT5A 1U70A 3M08A 4KY8A 1DR3A 3FQZA 1DG7A 3IRNA 1PD8A 3JSUA 5ECXA 3N0HA 2AZNA 2ANQA 1KLKA 3NXYA 1AO8A 4KNEA 1DR5A 5HQYA 1MVSA 3GYFA 1E26A 2W9GA 4XT6A 3FQCA 2GD9A 3NZAX 3NZ9X 2ITHA 3QLYA 3KJSA 1CZ3A 3CLBA 4PDJA 5FDAA 3FRDX 4IXFX 1JUVA 7DFRA 4LAGX 3KY8A 3NXXA 3SRQX 5DFRA 1HFRA 3QFXA 3FL9A 1DR1A 1U72A 1S3VA 1OHJA 4XRBA 3DFRA 2H2QA 1OHKA 1RB3A 3D84X 3M09A 1JOMA 1DR7A 3JWKA 3UM5A 3IRMA 1IA2A 3IROA 3D80A 4DP3A 4QJZD 3FRFX 3S9UA 1BOZA 5JG0X 4ELGA 1RA8A 3DRCA 4RGCA 4HOFA 3E0BA 4G95A 1SEJA 5HI6A 3F91A 4PSTA 3JWCA 6DFRA 2L28A 3DG8A 4XT4A 4M7UA 3NXOA 1DRAA 3TQ9A 1ZDRA 1RH3A 3FQFA 3UM8A 2JYBA 2HQPA 3K45A 3TQAA 4KLXA 2ZZAA 5HPBA 3JWMA 3KGYA 1RX9A 1D1GA 4HOEA 4KL9A 1AOEA 4ELFA 2C2SA 3F8ZA 1DRBA 1S3YA 4KJLA 3FQVA 3FS6A 3HBBA 3QLWA 4X5IA 1RX1A 4LAEX 4EIZA 3KFYA 1DISA 3QG2A 5EAJA 3VCOA 3F0XX 2FZHA 3FQ0A 3TQ8A 2DRCA 1IA3A 8DFRA 3FL8A 3GI2A 4KBNA 1DYRA 1DG8A 1RB2A 4LEKX 4KM2A 1S3WA 3QYLA 3F8YA 3K47A 4KJJA 3SGYA 1HFPA 1DYHA 1JOLA 3QGTA 3QLXA 1DR6A 1M7AA 4EILA 1CD2A 2W3VA 4X5FA 1RE7A 3NXRA 3RO9A 3QLSA 4Q6AA 4QLGA 5CC9A 1DLSA 1DREA 4KY4A 3F0SX 3EEMA 3SRRX 5HF2X 2DHFA 4XT7A 3NRRA 3ROAA 1DYJA 5HF0X 1RX3A 1DR4A 3DGAA 1RX7A 3DATA 3SA2A 4M2XA 2CD2A 3RG9A 2HM9A 2W3AA 4P66A 4I13A 1RX5A 4KFJA 1DHJA 4HA7A 4ELHA 4PSYA 4XECX 1KMSA 3JW5A 3FY9X 4FHBA 1RX4A 3NXVA 1IA4A 4H97A 3NZCX 1PD9A 4GH8A 1RA3A 3HJ3A 4FGGA 3K74A 4P3QA 1DYIA 1YHOA 1RX2A 2W3BA 1RF7A 3ZPGA 1DRHA 3CD2A 4Q67A 2INQA 2CIGA 2W9TA 1LY4A 2W9HA 4H95A 4X5JA 3IA5A 2BLBA 3S7AA 2B3ZA 3TQBA 4KD7A 1RA9A 1DG5A 4IXGX 3INVA 2FZJA 4I1NA 4LAHX 3JVXA 4ELEA 4M6LA 4G8ZX 4HA9A 3DAUA 2HXVA 1J3IA 2QK8A 1HFQA 3QLZA 3FYVX 4ELBA 2LF1A 1M79A 1AI9A 3EELA 1RA2A 1MVTA 1DAJA 3IA4A 3FRAX 3CL9A 3SQYX 3F0BX 2OIPA 3SA1A 1QZFA 4QJCA 3TD8A 4Q0EA 2FZIA 3ZPCA 4H96A 4XE6X 4Q0DA 3QYOA 3SRUX 3F0QX 2P4GA 3EEKA 1J3JA 1DIUA 2W9SA 5DXVA 3QLRA 4PTHA 4EJ1A 1RD7A 1RC4A 4DPHA 3NZBX 5HSUA 4KEBA 4QLEA 1DHFA 4NX7A 4XT8A 1DR2A 3SR5X 4M6JA 3DL5A 4P68A 3KJRA 4P3RA 3EEJA 3OCHA 2D5NA 4QHVA 4OR7A 2XW7A 3FREX 3FQOA 4QLFA 4ECKA 1J3KA 3NTZA 1M78A 3SRWX 2W3MA 3NU0A 3NZDA 4DDRA 3FRBX 4HOGA 3S3VA 4KJKA 2C2TA 2G6VA 4IXED 4OSGA 1VDRA 1RA1A 5U26A 4FGHA 3F0VX 1BZFA 1LY3A 3GHWA 3SRSX 3QL3A 1RX6A 4X5GA 4CD2A 3GHCA 1KMVA 2D0KA 5HSRA 1DDSA 4M6KA 4H98A 3F0UX 5HQZA 3NZ6X 5HT4A 5HVBA 3K2HA 3OAFA 3GHVA 3NXTA 3FY8X 4KAKA 2BLAA 3JW3A 2BL9A 1DDRA 3JTWA 5JA3A 5HT5A 5E8QA 5U27A 4PTJA 1VJ3A 1RG7A 3FYWX 4PSSA 1IA1A 3DL6A 1TDRA 3EX8A 4KM0A 1DHIA 4G3MA 2W3WA 4TU5X 1S3UA 4NX6A 2BLCA 2O7PA 4X5HA 3R33A 4DPDA 5ECCA 3SH2A 2ANOA 3L3RA 5HVEA 3JWFA 3I8AX 1DLRA 1DF7A 3LG4A 4EIGA 3EIGA 3QL0A 3Q1HA 5HUIA 2OBCA 3UM6A 3I3RA 4M7VA 4QI9A 4KYAA 3CSEA 1RX8A 1PDBA 3IX9A
chains in the Genus database with same CATH topology
1U71A 4DFRA 2KGKA 5CCCA 1DRFA 1LUDA 3SAIA 4XT5A 1U70A 3M08A 4KY8A 1DR3A 3FQZA 1DG7A 3IRNA 1PD8A 3JSUA 5ECXA 3N0HA 2AZNA 2ANQA 1KLKA 3NXYA 1AO8A 4KNEA 1DR5A 5HQYA 1MVSA 3GYFA 1E26A 2W9GA 4XT6A 3FQCA 2GD9A 3NZAX 3NZ9X 2ITHA 3QLYA 3KJSA 1CZ3A 3CLBA 4PDJA 5FDAA 3FRDX 4IXFX 1JUVA 7DFRA 4LAGX 3KY8A 3NXXA 3SRQX 5DFRA 1HFRA 3QFXA 3FL9A 1DR1A 1U72A 1S3VA 1OHJA 4XRBA 3DFRA 2H2QA 1OHKA 1RB3A 3D84X 3M09A 1JOMA 1DR7A 3JWKA 3UM5A 3IRMA 1IA2A 3IROA 3D80A 4DP3A 4QJZD 3FRFX 3S9UA 1BOZA 5JG0X 4ELGA 1RA8A 3DRCA 4RGCA 4HOFA 3E0BA 4G95A 1SEJA 5HI6A 3F91A 4PSTA 3JWCA 6DFRA 2L28A 3DG8A 4XT4A 4M7UA 3NXOA 1DRAA 3TQ9A 1ZDRA 1RH3A 3FQFA 3UM8A 2JYBA 2HQPA 3K45A 3TQAA 4KLXA 2ZZAA 5HPBA 3JWMA 3KGYA 1RX9A 1D1GA 4HOEA 4KL9A 1AOEA 4ELFA 2C2SA 3F8ZA 1DRBA 1S3YA 4KJLA 3FQVA 3FS6A 3HBBA 3QLWA 4X5IA 1RX1A 4LAEX 4EIZA 3KFYA 1DISA 3QG2A 5EAJA 3VCOA 3F0XX 2FZHA 3FQ0A 3TQ8A 2DRCA 1IA3A 8DFRA 3FL8A 3GI2A 4KBNA 1DYRA 1DG8A 1RB2A 4LEKX 4KM2A 1S3WA 3QYLA 3F8YA 3K47A 4KJJA 3SGYA 1HFPA 1DYHA 1JOLA 3QGTA 3QLXA 1DR6A 1M7AA 4EILA 1CD2A 2W3VA 4X5FA 1RE7A 3NXRA 3RO9A 3QLSA 4Q6AA 4QLGA 5CC9A 1DLSA 1DREA 4KY4A 3F0SX 3EEMA 3SRRX 5HF2X 2DHFA 4XT7A 3NRRA 3ROAA 1DYJA 5HF0X 1RX3A 1DR4A 3DGAA 1RX7A 3DATA 3SA2A 4M2XA 2CD2A 3RG9A 2HM9A 2W3AA 4P66A 4I13A 1RX5A 4KFJA 1DHJA 4HA7A 4ELHA 4PSYA 4XECX 1KMSA 3JW5A 3FY9X 4FHBA 1RX4A 3NXVA 1IA4A 4H97A 3NZCX 1PD9A 4GH8A 1RA3A 3HJ3A 4FGGA 3K74A 4P3QA 1DYIA 1YHOA 1RX2A 2W3BA 1RF7A 3ZPGA 1DRHA 3CD2A 4Q67A 2INQA 2CIGA 2W9TA 1LY4A 2W9HA 4H95A 4X5JA 3IA5A 2BLBA 3S7AA 2B3ZA 3TQBA 4KD7A 1RA9A 1DG5A 4IXGX 3INVA 2FZJA 4I1NA 4LAHX 3JVXA 4ELEA 4M6LA 4G8ZX 4HA9A 3DAUA 2HXVA 1J3IA 2QK8A 1HFQA 3QLZA 3FYVX 4ELBA 2LF1A 1M79A 1AI9A 3EELA 1RA2A 1MVTA 1DAJA 3IA4A 3FRAX 3CL9A 3SQYX 3F0BX 2OIPA 3SA1A 1QZFA 4QJCA 3TD8A 4Q0EA 2FZIA 3ZPCA 4H96A 4XE6X 4Q0DA 3QYOA 3SRUX 3F0QX 2P4GA 3EEKA 1J3JA 1DIUA 2W9SA 5DXVA 3QLRA 4PTHA 4EJ1A 1RD7A 1RC4A 4DPHA 3NZBX 5HSUA 4KEBA 4QLEA 1DHFA 4NX7A 4XT8A 1DR2A 3SR5X 4M6JA 3DL5A 4P68A 3KJRA 4P3RA 3EEJA 3OCHA 2D5NA 4QHVA 4OR7A 2XW7A 3FREX 3FQOA 4QLFA 4ECKA 1J3KA 3NTZA 1M78A 3SRWX 2W3MA 3NU0A 3NZDA 4DDRA 3FRBX 4HOGA 3S3VA 4KJKA 2C2TA 2G6VA 4IXED 4OSGA 1VDRA 1RA1A 5U26A 4FGHA 3F0VX 1BZFA 1LY3A 3GHWA 3SRSX 3QL3A 1RX6A 4X5GA 4CD2A 3GHCA 1KMVA 2D0KA 5HSRA 1DDSA 4M6KA 4H98A 3F0UX 5HQZA 3NZ6X 5HT4A 5HVBA 3K2HA 3OAFA 3GHVA 3NXTA 3FY8X 4KAKA 2BLAA 3JW3A 2BL9A 1DDRA 3JTWA 5JA3A 5HT5A 5E8QA 5U27A 4PTJA 1VJ3A 1RG7A 3FYWX 4PSSA 1IA1A 3DL6A 1TDRA 3EX8A 4KM0A 1DHIA 4G3MA 2W3WA 4TU5X 1S3UA 4NX6A 2BLCA 2O7PA 4X5HA 3R33A 4DPDA 5ECCA 3SH2A 2ANOA 3L3RA 5HVEA 3JWFA 3I8AX 1DLRA 1DF7A 3LG4A 4EIGA 3EIGA 3QL0A 3Q1HA 5HUIA 2OBCA 3UM6A 3I3RA 4M7VA 4QI9A 4KYAA 3CSEA 1RX8A 1PDBA 3IX9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U71 A;  4DFR A;  2KGK A;  5CCC A;  1DRF A;  1LUD A;  3SAI A;  4XT5 A;  1U70 A;  3M08 A;  4KY8 A;  1DR3 A;  3FQZ A;  1DG7 A;  3IRN A;  1PD8 A;  3JSU A;  5ECX A;  3N0H A;  2AZN A;  2ANQ A;  1KLK A;  3NXY A;  1AO8 A;  4KNE A;  1DR5 A;  5HQY A;  1MVS A;  3GYF A;  1E26 A;  2W9G A;  4XT6 A;  3FQC A;  2GD9 A;  3NZA X;  3NZ9 X;  2ITH A;  3QLY A;  3KJS A;  1CZ3 A;  3CLB A;  4PDJ A;  5FDA A;  3FRD X;  4IXF X;  1JUV A;  7DFR A;  4LAG X;  3KY8 A;  3NXX A;  3SRQ X;  5DFR A;  1HFR A;  3QFX A;  3FL9 A;  1DR1 A;  1U72 A;  1S3V A;  1OHJ A;  4XRB A;  3DFR A;  2H2Q A;  1OHK A;  1RB3 A;  3D84 X;  3M09 A;  1JOM A;  1DR7 A;  3JWK A;  3UM5 A;  3IRM A;  1IA2 A;  3IRO A;  3D80 A;  4DP3 A;  4QJZ D;  3FRF X;  3S9U A;  1BOZ A;  5JG0 X;  4ELG A;  1RA8 A;  3DRC A;  4RGC A;  4HOF A;  3E0B A;  4G95 A;  1SEJ A;  5HI6 A;  3F91 A;  4PST A;  3JWC A;  6DFR A;  2L28 A;  3DG8 A;  4XT4 A;  4M7U A;  3NXO A;  1DRA A;  3TQ9 A;  1ZDR A;  1RH3 A;  3FQF A;  3UM8 A;  2JYB A;  2HQP A;  3K45 A;  3TQA A;  4KLX A;  2ZZA A;  5HPB A;  3JWM A;  3KGY A;  1RX9 A;  1D1G A;  4HOE A;  4KL9 A;  1AOE A;  4ELF A;  2C2S A;  3F8Z A;  1DRB A;  1S3Y A;  4KJL A;  3FQV A;  3FS6 A;  3HBB A;  3QLW A;  4X5I A;  1RX1 A;  4LAE X;  4EIZ A;  3KFY A;  1DIS A;  3QG2 A;  5EAJ A;  3VCO A;  3F0X X;  2FZH A;  3FQ0 A;  3TQ8 A;  2DRC A;  1IA3 A;  8DFR A;  3FL8 A;  3GI2 A;  4KBN A;  1DYR A;  1DG8 A;  1RB2 A;  4LEK X;  4KM2 A;  1S3W A;  3QYL A;  3F8Y A;  3K47 A;  4KJJ A;  3SGY A;  1HFP A;  1DYH A;  1JOL A;  3QGT A;  3QLX A;  1DR6 A;  1M7A A;  4EIL A;  1CD2 A;  2W3V A;  4X5F A;  1RE7 A;  3NXR A;  3RO9 A;  3QLS A;  4Q6A A;  4QLG A;  5CC9 A;  1DLS A;  1DRE A;  4KY4 A;  3F0S X;  3EEM A;  3SRR X;  5HF2 X;  2DHF A;  4XT7 A;  3NRR A;  3ROA A;  1DYJ A;  5HF0 X;  1RX3 A;  1DR4 A;  3DGA A;  1RX7 A;  3DAT A;  3SA2 A;  4M2X A;  2CD2 A;  3RG9 A;  2HM9 A;  2W3A A;  4P66 A;  4I13 A;  1RX5 A;  4KFJ A;  1DHJ A;  4HA7 A;  4ELH A;  4PSY A;  4XEC X;  1KMS A;  3JW5 A;  3FY9 X;  4FHB A;  1RX4 A;  3NXV A;  1IA4 A;  4H97 A;  3NZC X;  1PD9 A;  4GH8 A;  1RA3 A;  3HJ3 A;  4FGG A;  3K74 A;  4P3Q A;  1DYI A;  1YHO A;  1RX2 A;  2W3B A;  1RF7 A;  3ZPG A;  1DRH A;  3CD2 A;  4Q67 A;  2INQ A;  2CIG A;  2W9T A;  1LY4 A;  2W9H A;  4H95 A;  4X5J A;  3IA5 A;  2BLB A;  3S7A A;  2B3Z A;  3TQB A;  4KD7 A;  1RA9 A;  1DG5 A;  4IXG X;  3INV A;  2FZJ A;  4I1N A;  4LAH X;  3JVX A;  4ELE A;  4M6L A;  4G8Z X;  4HA9 A;  3DAU A;  2HXV A;  1J3I A;  2QK8 A;  1HFQ A;  3QLZ A;  3FYV X;  4ELB A;  2LF1 A;  1M79 A;  1AI9 A;  3EEL A;  1RA2 A;  1MVT A;  1DAJ A;  3IA4 A;  3FRA X;  3CL9 A;  3SQY X;  3F0B X;  2OIP A;  3SA1 A;  1QZF A;  4QJC A;  3TD8 A;  4Q0E A;  2FZI A;  3ZPC A;  4H96 A;  4XE6 X;  4Q0D A;  3QYO A;  3SRU X;  3F0Q X;  2P4G A;  3EEK A;  1J3J A;  1DIU A;  2W9S A;  5DXV A;  3QLR A;  4PTH A;  4EJ1 A;  1RD7 A;  1RC4 A;  4DPH A;  3NZB X;  5HSU A;  4KEB A;  4QLE A;  1DHF A;  4NX7 A;  4XT8 A;  1DR2 A;  3SR5 X;  4M6J A;  3DL5 A;  4P68 A;  3KJR A;  4P3R A;  3EEJ A;  3OCH A;  2D5N A;  4QHV A;  4OR7 A;  2XW7 A;  3FRE X;  3FQO A;  4QLF A;  4ECK A;  1J3K A;  3NTZ A;  1M78 A;  3SRW X;  2W3M A;  3NU0 A;  3NZD A;  4DDR A;  3FRB X;  4HOG A;  3S3V A;  4KJK A;  2C2T A;  2G6V A;  4IXE D;  4OSG A;  1VDR A;  1RA1 A;  5U26 A;  4FGH A;  3F0V X;  1BZF A;  1LY3 A;  3GHW A;  3SRS X;  3QL3 A;  1RX6 A;  4X5G A;  4CD2 A;  3GHC A;  1KMV A;  2D0K A;  5HSR A;  1DDS A;  4M6K A;  4H98 A;  3F0U X;  5HQZ A;  3NZ6 X;  5HT4 A;  5HVB A;  3K2H A;  3OAF A;  3GHV A;  3NXT A;  3FY8 X;  4KAK A;  2BLA A;  3JW3 A;  2BL9 A;  1DDR A;  3JTW A;  5JA3 A;  5HT5 A;  5E8Q A;  5U27 A;  4PTJ A;  1VJ3 A;  1RG7 A;  3FYW X;  4PSS A;  1IA1 A;  3DL6 A;  1TDR A;  3EX8 A;  4KM0 A;  1DHI A;  4G3M A;  2W3W A;  4TU5 X;  1S3U A;  4NX6 A;  2BLC A;  2O7P A;  4X5H A;  3R33 A;  4DPD A;  5ECC A;  3SH2 A;  2ANO A;  3L3R A;  5HVE A;  3JWF A;  3I8A X;  1DLR A;  1DF7 A;  3LG4 A;  4EIG A;  3EIG A;  3QL0 A;  3Q1H A;  5HUI A;  2OBC A;  3UM6 A;  3I3R A;  4M7V A;  4QI9 A;  4KYA A;  3CSE A;  1RX8 A;  1PDB A;  3IX9 A; 
#chains in the Genus database with same CATH topology
 1U71 A;  4DFR A;  2KGK A;  5CCC A;  1DRF A;  1LUD A;  3SAI A;  4XT5 A;  1U70 A;  3M08 A;  4KY8 A;  1DR3 A;  3FQZ A;  1DG7 A;  3IRN A;  1PD8 A;  3JSU A;  5ECX A;  3N0H A;  2AZN A;  2ANQ A;  1KLK A;  3NXY A;  1AO8 A;  4KNE A;  1DR5 A;  5HQY A;  1MVS A;  3GYF A;  1E26 A;  2W9G A;  4XT6 A;  3FQC A;  2GD9 A;  3NZA X;  3NZ9 X;  2ITH A;  3QLY A;  3KJS A;  1CZ3 A;  3CLB A;  4PDJ A;  5FDA A;  3FRD X;  4IXF X;  1JUV A;  7DFR A;  4LAG X;  3KY8 A;  3NXX A;  3SRQ X;  5DFR A;  1HFR A;  3QFX A;  3FL9 A;  1DR1 A;  1U72 A;  1S3V A;  1OHJ A;  4XRB A;  3DFR A;  2H2Q A;  1OHK A;  1RB3 A;  3D84 X;  3M09 A;  1JOM A;  1DR7 A;  3JWK A;  3UM5 A;  3IRM A;  1IA2 A;  3IRO A;  3D80 A;  4DP3 A;  4QJZ D;  3FRF X;  3S9U A;  1BOZ A;  5JG0 X;  4ELG A;  1RA8 A;  3DRC A;  4RGC A;  4HOF A;  3E0B A;  4G95 A;  1SEJ A;  5HI6 A;  3F91 A;  4PST A;  3JWC A;  6DFR A;  2L28 A;  3DG8 A;  4XT4 A;  4M7U A;  3NXO A;  1DRA A;  3TQ9 A;  1ZDR A;  1RH3 A;  3FQF A;  3UM8 A;  2JYB A;  2HQP A;  3K45 A;  3TQA A;  4KLX A;  2ZZA A;  5HPB A;  3JWM A;  3KGY A;  1RX9 A;  1D1G A;  4HOE A;  4KL9 A;  1AOE A;  4ELF A;  2C2S A;  3F8Z A;  1DRB A;  1S3Y A;  4KJL A;  3FQV A;  3FS6 A;  3HBB A;  3QLW A;  4X5I A;  1RX1 A;  4LAE X;  4EIZ A;  3KFY A;  1DIS A;  3QG2 A;  5EAJ A;  3VCO A;  3F0X X;  2FZH A;  3FQ0 A;  3TQ8 A;  2DRC A;  1IA3 A;  8DFR A;  3FL8 A;  3GI2 A;  4KBN A;  1DYR A;  1DG8 A;  1RB2 A;  4LEK X;  4KM2 A;  1S3W A;  3QYL A;  3F8Y A;  3K47 A;  4KJJ A;  3SGY A;  1HFP A;  1DYH A;  1JOL A;  3QGT A;  3QLX A;  1DR6 A;  1M7A A;  4EIL A;  1CD2 A;  2W3V A;  4X5F A;  1RE7 A;  3NXR A;  3RO9 A;  3QLS A;  4Q6A A;  4QLG A;  5CC9 A;  1DLS A;  1DRE A;  4KY4 A;  3F0S X;  3EEM A;  3SRR X;  5HF2 X;  2DHF A;  4XT7 A;  3NRR A;  3ROA A;  1DYJ A;  5HF0 X;  1RX3 A;  1DR4 A;  3DGA A;  1RX7 A;  3DAT A;  3SA2 A;  4M2X A;  2CD2 A;  3RG9 A;  2HM9 A;  2W3A A;  4P66 A;  4I13 A;  1RX5 A;  4KFJ A;  1DHJ A;  4HA7 A;  4ELH A;  4PSY A;  4XEC X;  1KMS A;  3JW5 A;  3FY9 X;  4FHB A;  1RX4 A;  3NXV A;  1IA4 A;  4H97 A;  3NZC X;  1PD9 A;  4GH8 A;  1RA3 A;  3HJ3 A;  4FGG A;  3K74 A;  4P3Q A;  1DYI A;  1YHO A;  1RX2 A;  2W3B A;  1RF7 A;  3ZPG A;  1DRH A;  3CD2 A;  4Q67 A;  2INQ A;  2CIG A;  2W9T A;  1LY4 A;  2W9H A;  4H95 A;  4X5J A;  3IA5 A;  2BLB A;  3S7A A;  2B3Z A;  3TQB A;  4KD7 A;  1RA9 A;  1DG5 A;  4IXG X;  3INV A;  2FZJ A;  4I1N A;  4LAH X;  3JVX A;  4ELE A;  4M6L A;  4G8Z X;  4HA9 A;  3DAU A;  2HXV A;  1J3I A;  2QK8 A;  1HFQ A;  3QLZ A;  3FYV X;  4ELB A;  2LF1 A;  1M79 A;  1AI9 A;  3EEL A;  1RA2 A;  1MVT A;  1DAJ A;  3IA4 A;  3FRA X;  3CL9 A;  3SQY X;  3F0B X;  2OIP A;  3SA1 A;  1QZF A;  4QJC A;  3TD8 A;  4Q0E A;  2FZI A;  3ZPC A;  4H96 A;  4XE6 X;  4Q0D A;  3QYO A;  3SRU X;  3F0Q X;  2P4G A;  3EEK A;  1J3J A;  1DIU A;  2W9S A;  5DXV A;  3QLR A;  4PTH A;  4EJ1 A;  1RD7 A;  1RC4 A;  4DPH A;  3NZB X;  5HSU A;  4KEB A;  4QLE A;  1DHF A;  4NX7 A;  4XT8 A;  1DR2 A;  3SR5 X;  4M6J A;  3DL5 A;  4P68 A;  3KJR A;  4P3R A;  3EEJ A;  3OCH A;  2D5N A;  4QHV A;  4OR7 A;  2XW7 A;  3FRE X;  3FQO A;  4QLF A;  4ECK A;  1J3K A;  3NTZ A;  1M78 A;  3SRW X;  2W3M A;  3NU0 A;  3NZD A;  4DDR A;  3FRB X;  4HOG A;  3S3V A;  4KJK A;  2C2T A;  2G6V A;  4IXE D;  4OSG A;  1VDR A;  1RA1 A;  5U26 A;  4FGH A;  3F0V X;  1BZF A;  1LY3 A;  3GHW A;  3SRS X;  3QL3 A;  1RX6 A;  4X5G A;  4CD2 A;  3GHC A;  1KMV A;  2D0K A;  5HSR A;  1DDS A;  4M6K A;  4H98 A;  3F0U X;  5HQZ A;  3NZ6 X;  5HT4 A;  5HVB A;  3K2H A;  3OAF A;  3GHV A;  3NXT A;  3FY8 X;  4KAK A;  2BLA A;  3JW3 A;  2BL9 A;  1DDR A;  3JTW A;  5JA3 A;  5HT5 A;  5E8Q A;  5U27 A;  4PTJ A;  1VJ3 A;  1RG7 A;  3FYW X;  4PSS A;  1IA1 A;  3DL6 A;  1TDR A;  3EX8 A;  4KM0 A;  1DHI A;  4G3M A;  2W3W A;  4TU5 X;  1S3U A;  4NX6 A;  2BLC A;  2O7P A;  4X5H A;  3R33 A;  4DPD A;  5ECC A;  3SH2 A;  2ANO A;  3L3R A;  5HVE A;  3JWF A;  3I8A X;  1DLR A;  1DF7 A;  3LG4 A;  4EIG A;  3EIG A;  3QL0 A;  3Q1H A;  5HUI A;  2OBC A;  3UM6 A;  3I3R A;  4M7V A;  4QI9 A;  4KYA A;  3CSE A;  1RX8 A;  1PDB A;  3IX9 A; 
#chains in the Genus database with same CATH homology
 1U71 A;  4DFR A;  2KGK A;  5CCC A;  1DRF A;  1LUD A;  3SAI A;  4XT5 A;  1U70 A;  3M08 A;  4KY8 A;  1DR3 A;  3FQZ A;  1DG7 A;  3IRN A;  1PD8 A;  3JSU A;  5ECX A;  3N0H A;  2AZN A;  2ANQ A;  1KLK A;  3NXY A;  1AO8 A;  4KNE A;  1DR5 A;  5HQY A;  1MVS A;  3GYF A;  1E26 A;  2W9G A;  4XT6 A;  3FQC A;  2GD9 A;  3NZA X;  3NZ9 X;  2ITH A;  3QLY A;  3KJS A;  1CZ3 A;  3CLB A;  4PDJ A;  5FDA A;  3FRD X;  4IXF X;  1JUV A;  7DFR A;  4LAG X;  3KY8 A;  3NXX A;  3SRQ X;  5DFR A;  1HFR A;  3QFX A;  3FL9 A;  1DR1 A;  1U72 A;  1S3V A;  1OHJ A;  4XRB A;  3DFR A;  2H2Q A;  1OHK A;  1RB3 A;  3D84 X;  3M09 A;  1JOM A;  1DR7 A;  3JWK A;  3UM5 A;  3IRM A;  1IA2 A;  3IRO A;  3D80 A;  4DP3 A;  4QJZ D;  3FRF X;  3S9U A;  1BOZ A;  5JG0 X;  4ELG A;  1RA8 A;  3DRC A;  4RGC A;  4HOF A;  3E0B A;  4G95 A;  1SEJ A;  5HI6 A;  3F91 A;  4PST A;  3JWC A;  6DFR A;  2L28 A;  3DG8 A;  4XT4 A;  4M7U A;  3NXO A;  1DRA A;  3TQ9 A;  1ZDR A;  1RH3 A;  3FQF A;  3UM8 A;  2JYB A;  2HQP A;  3K45 A;  3TQA A;  4KLX A;  2ZZA A;  5HPB A;  3JWM A;  3KGY A;  1RX9 A;  1D1G A;  4HOE A;  4KL9 A;  1AOE A;  4ELF A;  2C2S A;  3F8Z A;  1DRB A;  1S3Y A;  4KJL A;  3FQV A;  3FS6 A;  3HBB A;  3QLW A;  4X5I A;  1RX1 A;  4LAE X;  4EIZ A;  3KFY A;  1DIS A;  3QG2 A;  5EAJ A;  3VCO A;  3F0X X;  2FZH A;  3FQ0 A;  3TQ8 A;  2DRC A;  1IA3 A;  8DFR A;  3FL8 A;  3GI2 A;  4KBN A;  1DYR A;  1DG8 A;  1RB2 A;  4LEK X;  4KM2 A;  1S3W A;  3QYL A;  3F8Y A;  3K47 A;  4KJJ A;  3SGY A;  1HFP A;  1DYH A;  1JOL A;  3QGT A;  3QLX A;  1DR6 A;  1M7A A;  4EIL A;  1CD2 A;  2W3V A;  4X5F A;  1RE7 A;  3NXR A;  3RO9 A;  3QLS A;  4Q6A A;  4QLG A;  5CC9 A;  1DLS A;  1DRE A;  4KY4 A;  3F0S X;  3EEM A;  3SRR X;  5HF2 X;  2DHF A;  4XT7 A;  3NRR A;  3ROA A;  1DYJ A;  5HF0 X;  1RX3 A;  1DR4 A;  3DGA A;  1RX7 A;  3DAT A;  3SA2 A;  4M2X A;  2CD2 A;  3RG9 A;  2HM9 A;  2W3A A;  4P66 A;  4I13 A;  1RX5 A;  4KFJ A;  1DHJ A;  4HA7 A;  4ELH A;  4PSY A;  4XEC X;  1KMS A;  3JW5 A;  3FY9 X;  4FHB A;  1RX4 A;  3NXV A;  1IA4 A;  4H97 A;  3NZC X;  1PD9 A;  4GH8 A;  1RA3 A;  3HJ3 A;  4FGG A;  3K74 A;  4P3Q A;  1DYI A;  1YHO A;  1RX2 A;  2W3B A;  1RF7 A;  3ZPG A;  1DRH A;  3CD2 A;  4Q67 A;  2INQ A;  2CIG A;  2W9T A;  1LY4 A;  2W9H A;  4H95 A;  4X5J A;  3IA5 A;  2BLB A;  3S7A A;  2B3Z A;  3TQB A;  4KD7 A;  1RA9 A;  1DG5 A;  4IXG X;  3INV A;  2FZJ A;  4I1N A;  4LAH X;  3JVX A;  4ELE A;  4M6L A;  4G8Z X;  4HA9 A;  3DAU A;  2HXV A;  1J3I A;  2QK8 A;  1HFQ A;  3QLZ A;  3FYV X;  4ELB A;  2LF1 A;  1M79 A;  1AI9 A;  3EEL A;  1RA2 A;  1MVT A;  1DAJ A;  3IA4 A;  3FRA X;  3CL9 A;  3SQY X;  3F0B X;  2OIP A;  3SA1 A;  1QZF A;  4QJC A;  3TD8 A;  4Q0E A;  2FZI A;  3ZPC A;  4H96 A;  4XE6 X;  4Q0D A;  3QYO A;  3SRU X;  3F0Q X;  2P4G A;  3EEK A;  1J3J A;  1DIU A;  2W9S A;  5DXV A;  3QLR A;  4PTH A;  4EJ1 A;  1RD7 A;  1RC4 A;  4DPH A;  3NZB X;  5HSU A;  4KEB A;  4QLE A;  1DHF A;  4NX7 A;  4XT8 A;  1DR2 A;  3SR5 X;  4M6J A;  3DL5 A;  4P68 A;  3KJR A;  4P3R A;  3EEJ A;  3OCH A;  2D5N A;  4QHV A;  4OR7 A;  2XW7 A;  3FRE X;  3FQO A;  4QLF A;  4ECK A;  1J3K A;  3NTZ A;  1M78 A;  3SRW X;  2W3M A;  3NU0 A;  3NZD A;  4DDR A;  3FRB X;  4HOG A;  3S3V A;  4KJK A;  2C2T A;  2G6V A;  4IXE D;  4OSG A;  1VDR A;  1RA1 A;  5U26 A;  4FGH A;  3F0V X;  1BZF A;  1LY3 A;  3GHW A;  3SRS X;  3QL3 A;  1RX6 A;  4X5G A;  4CD2 A;  3GHC A;  1KMV A;  2D0K A;  5HSR A;  1DDS A;  4M6K A;  4H98 A;  3F0U X;  5HQZ A;  3NZ6 X;  5HT4 A;  5HVB A;  3K2H A;  3OAF A;  3GHV A;  3NXT A;  3FY8 X;  4KAK A;  2BLA A;  3JW3 A;  2BL9 A;  1DDR A;  3JTW A;  5JA3 A;  5HT5 A;  5E8Q A;  5U27 A;  4PTJ A;  1VJ3 A;  1RG7 A;  3FYW X;  4PSS A;  1IA1 A;  3DL6 A;  1TDR A;  3EX8 A;  4KM0 A;  1DHI A;  4G3M A;  2W3W A;  4TU5 X;  1S3U A;  4NX6 A;  2BLC A;  2O7P A;  4X5H A;  3R33 A;  4DPD A;  5ECC A;  3SH2 A;  2ANO A;  3L3R A;  5HVE A;  3JWF A;  3I8A X;  1DLR A;  1DF7 A;  3LG4 A;  4EIG A;  3EIG A;  3QL0 A;  3Q1H A;  5HUI A;  2OBC A;  3UM6 A;  3I3R A;  4M7V A;  4QI9 A;  4KYA A;  3CSE A;  1RX8 A;  1PDB A;  3IX9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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