2XA7A

Ap2 clathrin adaptor core in active complex with cargo peptides
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
613
structure length
613
Chain Sequence
GMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKKKKG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
pubmed doi rcsb
molecule keywords ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT
molecule tags Protein transport
source organism Rattus norvegicus
total genus 194
structure length 613
sequence length 613
ec nomenclature
pdb deposition date 2010-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01602 Adaptin_N Adaptin N terminal region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat Variant 2xa7A01
1U6GC 3NMZA 2Z5MA 5FC8E 1UPKA 5HUWC 3Q0OA 3O2SA 3UKWB 3ZIRA 2IAEA 4BA3A 1WA5C 3Q0MA 3PSTA 4UAEA 3O2TA 4EV9A 1UPLA 2IWHA 4I2ZA 2JKTA 4U5NA 5AEIA 4PLQA 4UAFB 4YI0C 4FZAA 4A0CA 5LSWA 4CRVB 3BCTA 4I5LA 2JKRB 5BZUA 1EJLI 3OPBA 2VGLB 5E6QB 3Q0RA 3V74A 3ZIOA 2W3CA 3AU3A 3UKYB 4H3KA 3EA5B 3VWAA 3DW8A 4JLQA 1QGRA 3UKZB 2IE4A 1TH1A 4R11A 3K49A 1BK6A 1G3JA 2C1MA 2IX3A 3BSXA 3BSBA 3ND2A 5CTTA 4PLSA 2C1TA 4I2WA 1EE5A 4UQIB 4D49A 4B8OA 5EWPA 4WV6A 2BKUB 3K5YA 3Q0PA 4QMHA 3H3DX 3QHEA 2DB0A 3K7WA 4DVGB 1Q1SC 1PJNB 4GMOA 4BQKA 1I7XA 3ZHPA 4YJEA 4CB9A 4GMNA 1WA5B 1JPWA 5JJAA 3O2QA 3K5QA 2WTKA 3K61A 3BX2A 2Q5DA 3NMWA 4OO6A 1W63A 2PF4A 2YNSA 4RV1A 4B8PA 1V18A 4U5LA 3Q0QA 3LTMA 3WOZA 1JPPA 4O27A 1Y2AC 5BYMA 1IQ1C 1M8ZA 2Z5JA 5BZ5A 3BX3A 4U58A 1UKLA 4UADA 2Z5OA 1PJMB 3UKXB 4ADYA 4U5UA 4G3AA 4UWXA 1OYZA 4DB9A 2NPPB 4ZDUA 1IALA 3GVTA 3WOYA 3QMLC 4CRUB 3K7VA 2BAPA 3GB8A 4FQ3A 2IAEB 1QBKB 1QZ7A 4EV8A 4YGXA 2FV2A 5SVZA 1F59A 3L6XA 1M8XA 4DB8A 2XA7A 2QMRA 3L3QA 3A6PA 2JKRA 4U54A 3UL1B 3GQ2A 2VGLA 2NYLB 3GVOA 4P6ZG 3BTRC 4U5VA 3GAEA 2RU4A 1UN0A 3W3UA 3Q5UA 3UL0B 5KLRB 4MFVA 1Q1TC 3RZ9A 2X1GF 2F31A 4UQIA 1M5NS 3K4EA 3RZXA 3TT9A 3TPOA 3OUXA 1BK5A 3BWTA 4FZDA 4FDDA 3FGAB 1Z2CB 3EG5B 1O6PA 3QGBA 3OUWA 5BZVA 3KNDA 3VE6A 3EBBA 2Z5NA 3NOWA 4IMIA 3K5ZA 1M1EA 4JW2B 3WPTA 4MZ6E 5D5KC 2IE3A 3T7UA 5HHGE 4QMJA 4HM9A 3WYFC 4EVTA 4V3QA 2PKGA 5DN7A 5KL8A 3ZINA 1JDHA 2OT8A 3ZIQA 5EKFA 3TJZB 1GCJA 1XQSA 4CV5B 2H4MA 4CBAA 2NYMB 5EKGA 4NZWA 4LACA 1M8YA 4Y5JA 5K6SA 3ODSA 3UVUA 3O4XA 4TNMA 2NPPA 4RXHB 3V6YA 4YK6A 4B18A 4IMJA 1IBRB 3L3FX 1B3UA 5KLAA 4MZ5E 3GS3A 2JKTB 3LWWA 3K64A 2X19B 3QGCA 1W9CA 4K92A 4R10A 4K6JA 3K62A 4U5SA 3ODRA 5J3VA 2YJYA 1I7WA 4DB6A 4V3OA 2XA7B 2QK1A 2NYLA 4EVAA 1EJYI 3TPMA 4CT6B 4EVPA 4DJSA 4D4EA 5SWFA 4OIHA 3FEYC 4H3HA 4FFBC 3DADA 2RU4B 2JAKA 4PVZA 4RZPA 1M8WA 4B8JA 5KLTB 4E4VA 4DBAA 3L6YA 3IBVA 3C2HA 5H2XA 1O6OA 4PLRA 4HNMA 4CT7B 3OQSA 1QGKA 4U5OA 4XZRB 3FGAA 3GRLA 1EE4A 5B56A 4R0ZA 4FZFA 3TJ3A 3FEXC 5KL1A 2BNXA 1LUJA 4L7MA 2Z6GA 4HXTA 4CB8A 2Z6HA 3LTJA 5SW9A 3PSPA 2QNAA 1T08A 4QMIA 3ZIPA 5K9SA 4BPLA 1HO8A 2GL7A 1LRVA 3Q0LA 2IW3A 2QK2A 2OF3A 3C5WA 1W63B 2P8QA 2BCTA 4YJLA 3ZKVA 4HTVA 3V71A 2YNRA 3NMXA 5BZ1A 5HUYC 3Q0SA 5H2WA 1IB2A 4I5NA 4MFUA 3IFQA 3TX7A 4DZSA 2Z5KA 2JDQA 1XM9A 2NYMA 4P6ZB 1XQRA 4U3JC 4KZGA 4V3RA 3Q0NA 3C2GA 3OBVA 3GNIA 4NEEA 3QG9A
chains in the Genus database with same CATH superfamily
1U6GC 3NMZA 2Z5MA 5FC8E 1UPKA 3SLAA 5HUWC 3Q0OA 3O2SA 3UKWB 3ZIRA 2IAEA 4BA3A 1WA5C 3Q0MA 3PSTA 4UAEA 3O2TA 4EV9A 1UPLA 2IWHA 4I2ZA 2JKTA 4U5NA 5AEIA 4PLQA 4UAFB 4YI0C 4FZAA 3JXYA 3SL9A 4I2SA 4A0CA 5LSWA 4CRVB 3BCTA 4I5LA 2JKRB 5BZUA 1EJLI 2XOAA 3OPBA 2VGLB 5E6QB 3Q0RA 3V74A 3ZIOA 2W3CA 3AU3A 3UKYB 4H3KA 4JKQA 3EA5B 3VWAA 3DW8A 1N4KA 4JLQA 5CL7A 1QGRA 3UKZB 2IE4A 1TH1A 4R11A 3K49A 1BK6A 1G3JA 4L4IA 2C1MA 4I0YA 2IX3A 3BSXA 3BSBA 3ND2A 5CTTA 4PLSA 2C1TA 4I2WA 1EE5A 4UQIB 4D49A 3JY1A 4B8OA 5EWPA 3UJ0A 4WV6A 2BKUB 3K5YA 3JX7A 3Q0PA 4QMHA 3H3DX 3QHEA 2DB0A 3K7WA 4DVGB 1Q1SC 1PJNB 4GMOA 4BQKA 1I7XA 3ZHPA 4YJEA 4CB9A 4GMNA 1WA5B 1JPWA 5JJAA 3O2QA 3K5QA 2WTKA 3K61A 3BX2A 3VLEA 2Q5DA 3NMWA 3BVSA 1W63A 4OO6A 2PF4A 3VLDA 2YNSA 4RV1A 4B8PA 1V18A 4U5LA 3Q0QA 3LTMA 3WOZA 1JPPA 4O27A 1Y2AC 5BYMA 1IQ1C 1M8ZA 2Z5JA 3T8SA 5BZ5A 3BX3A 4U58A 4FP7A 1UKLA 4UADA 2Z5OA 5CL6A 1PJMB 3UKXB 4ADYA 4U5UA 4G3AA 4UWXA 1OYZA 4DB9A 2NPPB 4ZDUA 1IALA 3GVTA 3WOYA 3QMLC 4CRUB 3K7VA 1LSHA 2BAPA 3GB8A 4FQ3A 2IAEB 1QBKB 1QZ7A 5CLEA 4EV8A 4YGXA 2FV2A 5SVZA 1F59A 3L6XA 3ZILA 1M8XA 4DB8A 2XA7A 2QMRA 3L3QA 3A6PA 2JKRA 4U54A 3UL1B 3GQ2A 4A3VA 2VGLA 2NYLB 3GVOA 4P6ZG 3BTRC 4U5VA 3GAEA 2RU4A 1UN0A 3W3UA 3Q5UA 3UL0B 5KLRB 5CL5A 4MFVA 1Q1TC 3RZ9A 2X1GF 5CL9A 2F31A 4I8MA 4UQIA 1M5NS 5CLDA 3K4EA 3RZXA 3TT9A 3TPOA 3OUXA 1BK5A 3BWTA 4FZDA 4FDDA 3FGAB 1Z2CB 3EG5B 1O6PA 3QGBA 3OUWA 5BZVA 3KNDA 3VLFA 3VE6A 3EBBA 2Z5NA 3NOWA 4IMIA 3K5ZA 1M1EA 4JW2B 3WPTA 4MZ6E 5D5KC 2IE3A 3T7UA 5HHGE 4QMJA 4JW3C 4L4HA 4HM9A 3WYFC 4EVTA 4V3QA 2PKGA 5DN7A 5KL8A 3ZINA 1JDHA 2OT8A 3ZIQA 5EKFA 3TJZB 4I3NA 1GCJA 1XQSA 4CV5B 2H4MA 4CBAA 2NYMB 5EKGA 4NZWA 4I37A 4LACA 1M8YA 4Y5JA 5K6SA 3UJ4A 3ODSA 3UVUA 3O4XA 3JXZA 5CL8A 4TNMA 2NPPA 4RXHB 3V6YA 4YK6A 4B18A 4IMJA 1IBRB 3L3FX 1B3UA 5KLAA 4MZ5E 3GS3A 2JKTB 3LWWA 3K64A 2X19B 3QGCA 1W9CA 4K92A 4R10A 4K6JA 3K62A 4U5SA 3ODRA 5J3VA 2YJYA 1I7WA 4DB6A 4I1EA 4V3OA 2XA7B 2QK1A 2NYLA 4EVAA 1EJYI 3TPMA 4CT6B 4EVPA 4DJSA 4D4EA 5SWFA 4OIHA 3FEYC 4H3HA 4FFBC 3DADA 2RU4B 2JAKA 4PVZA 4RZPA 1M8WA 4B8JA 5KLTB 4E4VA 4DBAA 3L6YA 3IBVA 5CL4A 3C2HA 5H2XA 1O6OA 4PLRA 4HNMA 4CT7B 3OQSA 1QGKA 4I7IA 4U5OA 1TE4A 4XZRB 3FGAA 3GRLA 1EE4A 5B56A 4R0ZA 4FZFA 3TJ3A 3FEXC 5KL1A 2BNXA 1LUJA 4L7MA 2Z6GA 4HXTA 4CB8A 2Z6HA 3LTJA 5SW9A 5CLCA 3PSPA 5CLAA 2QNAA 4JW2A 1T08A 4QMIA 3ZIPA 4U2XD 5K9SA 4I96A 4BPLA 1HO8A 2GL7A 1LRVA 5CLBA 3Q0LA 2IW3A 2QK2A 2OF3A 3C5WA 4I6IA 1W63B 2P8QA 2BCTA 4YJLA 3ZKVA 4HTVA 3V71A 2YNRA 3NMXA 3ZIKA 5BZ1A 5HUYC 3Q0SA 5H2WA 1IB2A 4I5NA 5CL3A 4MFUA 3IFQA 3TX7A 4DZSA 2Z5KA 2JDQA 1XM9A 4A3TA 2NYMA 4P6ZB 1XQRA 4U3JC 4KZGA 4V3RA 3Q0NA 5KUBA 3C2GA 3OBVA 3GNIA 4NEEA 3QG9A
chains in the Genus database with same CATH topology
1U6GC 3NMZA 2Z5MA 5FC8E 1UPKA 3SLAA 5HUWC 3Q0OA 3O2SA 3UKWB 3ZIRA 2IAEA 4BA3A 1WA5C 3Q0MA 3PSTA 4UAEA 3O2TA 4EV9A 1UPLA 2IWHA 4I2ZA 2JKTA 4U5NA 5AEIA 4PLQA 4UAFB 4YI0C 4FZAA 3JXYA 3SL9A 4I2SA 4A0CA 5LSWA 4CRVB 3BCTA 4I5LA 2JKRB 5BZUA 1EJLI 2XOAA 3OPBA 2VGLB 5E6QB 3Q0RA 3V74A 3ZIOA 2W3CA 3AU3A 3UKYB 4H3KA 4JKQA 3EA5B 3VWAA 3DW8A 4JLQA 5CL7A 1QGRA 3UKZB 2IE4A 1TH1A 4R11A 3K49A 1BK6A 1G3JA 4L4IA 2C1MA 4I0YA 2IX3A 3BSXA 3BSBA 3ND2A 5CTTA 4PLSA 2C1TA 4I2WA 1EE5A 4UQIB 4D49A 3JY1A 4B8OA 5EWPA 4WV6A 2BKUB 3K5YA 3JX7A 3Q0PA 4QMHA 3H3DX 3QHEA 2DB0A 3K7WA 4DVGB 1Q1SC 1PJNB 4GMOA 4BQKA 1I7XA 3ZHPA 4YJEA 4CB9A 4GMNA 1WA5B 1JPWA 5JJAA 3O2QA 3K5QA 2WTKA 3K61A 3BX2A 3VLEA 2Q5DA 3NMWA 3BVSA 1W63A 4OO6A 2PF4A 3VLDA 2YNSA 4RV1A 4B8PA 1V18A 4U5LA 3Q0QA 3LTMA 3WOZA 1JPPA 4O27A 1Y2AC 5BYMA 1IQ1C 1M8ZA 2Z5JA 5BZ5A 3BX3A 4U58A 4FP7A 1UKLA 4UADA 2Z5OA 5CL6A 1PJMB 3UKXB 4ADYA 4U5UA 4G3AA 4UWXA 1OYZA 4DB9A 2NPPB 4ZDUA 1IALA 3GVTA 3WOYA 3QMLC 4CRUB 3K7VA 2BAPA 3GB8A 4FQ3A 2IAEB 1QBKB 1QZ7A 5CLEA 4EV8A 4YGXA 2FV2A 5SVZA 1F59A 3L6XA 3ZILA 1M8XA 4DB8A 2XA7A 2QMRA 3L3QA 3A6PA 2JKRA 4U54A 3UL1B 3GQ2A 4A3VA 2VGLA 2NYLB 3GVOA 4P6ZG 3BTRC 4U5VA 3GAEA 2RU4A 1UN0A 3W3UA 3Q5UA 3UL0B 5KLRB 5CL5A 4MFVA 1Q1TC 3RZ9A 2X1GF 5CL9A 2F31A 4I8MA 4UQIA 1M5NS 5CLDA 3K4EA 3RZXA 3TT9A 3TPOA 3OUXA 1BK5A 3BWTA 4FZDA 4FDDA 3FGAB 1Z2CB 3EG5B 1O6PA 3QGBA 3OUWA 5BZVA 3KNDA 3VLFA 3VE6A 3EBBA 2Z5NA 3NOWA 4IMIA 3K5ZA 1M1EA 4JW2B 3WPTA 4MZ6E 5D5KC 2IE3A 3T7UA 5HHGE 4QMJA 4JW3C 4L4HA 4HM9A 3WYFC 4EVTA 4V3QA 2PKGA 5DN7A 5KL8A 3ZINA 1JDHA 2OT8A 3ZIQA 5EKFA 3TJZB 4I3NA 1GCJA 1XQSA 4CV5B 2H4MA 4CBAA 2NYMB 5EKGA 4NZWA 4I37A 4LACA 1M8YA 4Y5JA 5K6SA 3ODSA 3UVUA 3O4XA 3JXZA 5CL8A 4TNMA 2NPPA 4RXHB 3V6YA 4YK6A 4B18A 4IMJA 1IBRB 3L3FX 1B3UA 5KLAA 4MZ5E 3GS3A 2JKTB 3LWWA 3K64A 2X19B 3QGCA 1W9CA 4K92A 4R10A 4K6JA 3K62A 4U5SA 3ODRA 5J3VA 2YJYA 1I7WA 4DB6A 4I1EA 4V3OA 2XA7B 2QK1A 2NYLA 4EVAA 1EJYI 3TPMA 4CT6B 4EVPA 4DJSA 4D4EA 5SWFA 4OIHA 3FEYC 4H3HA 4FFBC 3DADA 2RU4B 2JAKA 4PVZA 4RZPA 1M8WA 4B8JA 5KLTB 4E4VA 4DBAA 3L6YA 3IBVA 5CL4A 3C2HA 5H2XA 1O6OA 4PLRA 4HNMA 4CT7B 3OQSA 1QGKA 4I7IA 4U5OA 1TE4A 4XZRB 3FGAA 3GRLA 1EE4A 5B56A 4R0ZA 4FZFA 3TJ3A 3FEXC 5KL1A 2BNXA 1LUJA 4L7MA 2Z6GA 4HXTA 4CB8A 2Z6HA 3LTJA 5SW9A 5CLCA 3PSPA 5CLAA 2QNAA 4JW2A 1T08A 4QMIA 3ZIPA 4U2XD 5K9SA 4I96A 4BPLA 1HO8A 2GL7A 1LRVA 5CLBA 3Q0LA 2IW3A 2QK2A 2OF3A 3C5WA 4I6IA 1W63B 2P8QA 2BCTA 4YJLA 3ZKVA 4HTVA 3V71A 2YNRA 3NMXA 3ZIKA 5BZ1A 5HUYC 3Q0SA 5H2WA 1IB2A 4I5NA 5CL3A 4MFUA 3IFQA 3TX7A 4DZSA 2Z5KA 2JDQA 1XM9A 4A3TA 2NYMA 4P6ZB 1XQRA 4U3JC 4KZGA 4V3RA 3Q0NA 5KUBA 3C2GA 3OBVA 3GNIA 4NEEA 3QG9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U6G C;  3NMZ A;  2Z5M A;  5FC8 E;  1UPK A;  5HUW C;  3Q0O A;  3O2S A;  3UKW B;  3ZIR A;  2IAE A;  4BA3 A;  1WA5 C;  3Q0M A;  3PST A;  4UAE A;  3O2T A;  4EV9 A;  1UPL A;  2IWH A;  4I2Z A;  2JKT A;  4U5N A;  5AEI A;  4PLQ A;  4UAF B;  4YI0 C;  4FZA A;  4A0C A;  5LSW A;  4CRV B;  3BCT A;  4I5L A;  2JKR B;  5BZU A;  1EJL I;  3OPB A;  2VGL B;  5E6Q B;  3Q0R A;  3V74 A;  3ZIO A;  2W3C A;  3AU3 A;  3UKY B;  4H3K A;  3EA5 B;  3VWA A;  3DW8 A;  4JLQ A;  1QGR A;  3UKZ B;  2IE4 A;  1TH1 A;  4R11 A;  3K49 A;  1BK6 A;  1G3J A;  2C1M A;  2IX3 A;  3BSX A;  3BSB A;  3ND2 A;  5CTT A;  4PLS A;  2C1T A;  4I2W A;  1EE5 A;  4UQI B;  4D49 A;  4B8O A;  5EWP A;  4WV6 A;  2BKU B;  3K5Y A;  3Q0P A;  4QMH A;  3H3D X;  3QHE A;  2DB0 A;  3K7W A;  4DVG B;  1Q1S C;  1PJN B;  4GMO A;  4BQK A;  1I7X A;  3ZHP A;  4YJE A;  4CB9 A;  4GMN A;  1WA5 B;  1JPW A;  5JJA A;  3O2Q A;  3K5Q A;  2WTK A;  3K61 A;  3BX2 A;  2Q5D A;  3NMW A;  4OO6 A;  1W63 A;  2PF4 A;  2YNS A;  4RV1 A;  4B8P A;  1V18 A;  4U5L A;  3Q0Q A;  3LTM A;  3WOZ A;  1JPP A;  4O27 A;  1Y2A C;  5BYM A;  1IQ1 C;  1M8Z A;  2Z5J A;  5BZ5 A;  3BX3 A;  4U58 A;  1UKL A;  4UAD A;  2Z5O A;  1PJM B;  3UKX B;  4ADY A;  4U5U A;  4G3A A;  4UWX A;  1OYZ A;  4DB9 A;  2NPP B;  4ZDU A;  1IAL A;  3GVT A;  3WOY A;  3QML C;  4CRU B;  3K7V A;  2BAP A;  3GB8 A;  4FQ3 A;  2IAE B;  1QBK B;  1QZ7 A;  4EV8 A;  4YGX A;  2FV2 A;  5SVZ A;  1F59 A;  3L6X A;  1M8X A;  4DB8 A;  2XA7 A;  2QMR A;  3L3Q A;  3A6P A;  2JKR A;  4U54 A;  3UL1 B;  3GQ2 A;  2VGL A;  2NYL B;  3GVO A;  4P6Z G;  3BTR C;  4U5V A;  3GAE A;  2RU4 A;  1UN0 A;  3W3U A;  3Q5U A;  3UL0 B;  5KLR B;  4MFV A;  1Q1T C;  3RZ9 A;  2X1G F;  2F31 A;  4UQI A;  1M5N S;  3K4E A;  3RZX A;  3TT9 A;  3TPO A;  3OUX A;  1BK5 A;  3BWT A;  4FZD A;  4FDD A;  3FGA B;  1Z2C B;  3EG5 B;  1O6P A;  3QGB A;  3OUW A;  5BZV A;  3KND A;  3VE6 A;  3EBB A;  2Z5N A;  3NOW A;  4IMI A;  3K5Z A;  1M1E A;  4JW2 B;  3WPT A;  4MZ6 E;  5D5K C;  2IE3 A;  3T7U A;  5HHG E;  4QMJ A;  4HM9 A;  3WYF C;  4EVT A;  4V3Q A;  2PKG A;  5DN7 A;  5KL8 A;  3ZIN A;  1JDH A;  2OT8 A;  3ZIQ A;  5EKF A;  3TJZ B;  1GCJ A;  1XQS A;  4CV5 B;  2H4M A;  4CBA A;  2NYM B;  5EKG A;  4NZW A;  4LAC A;  1M8Y A;  4Y5J A;  5K6S A;  3ODS A;  3UVU A;  3O4X A;  4TNM A;  2NPP A;  4RXH B;  3V6Y A;  4YK6 A;  4B18 A;  4IMJ A;  1IBR B;  3L3F X;  1B3U A;  5KLA A;  4MZ5 E;  3GS3 A;  2JKT B;  3LWW A;  3K64 A;  2X19 B;  3QGC A;  1W9C A;  4K92 A;  4R10 A;  4K6J A;  3K62 A;  4U5S A;  3ODR A;  5J3V A;  2YJY A;  1I7W A;  4DB6 A;  4V3O A;  2XA7 B;  2QK1 A;  2NYL A;  4EVA A;  1EJY I;  3TPM A;  4CT6 B;  4EVP A;  4DJS A;  4D4E A;  5SWF A;  4OIH A;  3FEY C;  4H3H A;  4FFB C;  3DAD A;  2RU4 B;  2JAK A;  4PVZ A;  4RZP A;  1M8W A;  4B8J A;  5KLT B;  4E4V A;  4DBA A;  3L6Y A;  3IBV A;  3C2H A;  5H2X A;  1O6O A;  4PLR A;  4HNM A;  4CT7 B;  3OQS A;  1QGK A;  4U5O A;  4XZR B;  3FGA A;  3GRL A;  1EE4 A;  5B56 A;  4R0Z A;  4FZF A;  3TJ3 A;  3FEX C;  5KL1 A;  2BNX A;  1LUJ A;  4L7M A;  2Z6G A;  4HXT A;  4CB8 A;  2Z6H A;  3LTJ A;  5SW9 A;  3PSP A;  2QNA A;  1T08 A;  4QMI A;  3ZIP A;  5K9S A;  4BPL A;  1HO8 A;  2GL7 A;  1LRV A;  3Q0L A;  2IW3 A;  2QK2 A;  2OF3 A;  3C5W A;  1W63 B;  2P8Q A;  2BCT A;  4YJL A;  3ZKV A;  4HTV A;  3V71 A;  2YNR A;  3NMX A;  5BZ1 A;  5HUY C;  3Q0S A;  5H2W A;  1IB2 A;  4I5N A;  4MFU A;  3IFQ A;  3TX7 A;  4DZS A;  2Z5K A;  2JDQ A;  1XM9 A;  2NYM A;  4P6Z B;  1XQR A;  4U3J C;  4KZG A;  4V3R A;  3Q0N A;  3C2G A;  3OBV A;  3GNI A;  4NEE A;  3QG9 A; 
#chains in the Genus database with same CATH topology
 1U6G C;  3NMZ A;  2Z5M A;  5FC8 E;  1UPK A;  3SLA A;  5HUW C;  3Q0O A;  3O2S A;  3UKW B;  3ZIR A;  2IAE A;  4BA3 A;  1WA5 C;  3Q0M A;  3PST A;  4UAE A;  3O2T A;  4EV9 A;  1UPL A;  2IWH A;  4I2Z A;  2JKT A;  4U5N A;  5AEI A;  4PLQ A;  4UAF B;  4YI0 C;  4FZA A;  3JXY A;  3SL9 A;  4I2S A;  4A0C A;  5LSW A;  4CRV B;  3BCT A;  4I5L A;  2JKR B;  5BZU A;  1EJL I;  2XOA A;  3OPB A;  2VGL B;  5E6Q B;  3Q0R A;  3V74 A;  3ZIO A;  2W3C A;  3AU3 A;  3UKY B;  4H3K A;  4JKQ A;  3EA5 B;  3VWA A;  3DW8 A;  1N4K A;  4JLQ A;  5CL7 A;  1QGR A;  3UKZ B;  2IE4 A;  1TH1 A;  4R11 A;  3K49 A;  1BK6 A;  1G3J A;  4L4I A;  2C1M A;  4I0Y A;  2IX3 A;  3BSX A;  3BSB A;  3ND2 A;  5CTT A;  4PLS A;  2C1T A;  4I2W A;  1EE5 A;  4UQI B;  4D49 A;  3JY1 A;  4B8O A;  5EWP A;  3UJ0 A;  4WV6 A;  2BKU B;  3K5Y A;  3JX7 A;  3Q0P A;  4QMH A;  3H3D X;  3QHE A;  2DB0 A;  3K7W A;  4DVG B;  1Q1S C;  1PJN B;  4GMO A;  4BQK A;  1I7X A;  3ZHP A;  4YJE A;  4CB9 A;  4GMN A;  1WA5 B;  1JPW A;  5JJA A;  3O2Q A;  3K5Q A;  2WTK A;  3K61 A;  3BX2 A;  3VLE A;  2Q5D A;  3NMW A;  3BVS A;  1W63 A;  4OO6 A;  2PF4 A;  3VLD A;  2YNS A;  4RV1 A;  4B8P A;  1V18 A;  4U5L A;  3Q0Q A;  3LTM A;  3WOZ A;  1JPP A;  4O27 A;  1Y2A C;  5BYM A;  1IQ1 C;  1M8Z A;  2Z5J A;  3T8S A;  5BZ5 A;  3BX3 A;  4U58 A;  4FP7 A;  1UKL A;  4UAD A;  2Z5O A;  5CL6 A;  1PJM B;  3UKX B;  4ADY A;  4U5U A;  4G3A A;  4UWX A;  1OYZ A;  4DB9 A;  2NPP B;  4ZDU A;  1IAL A;  3GVT A;  3WOY A;  3QML C;  4CRU B;  3K7V A;  1LSH A;  2BAP A;  3GB8 A;  4FQ3 A;  2IAE B;  1QBK B;  1QZ7 A;  5CLE A;  4EV8 A;  4YGX A;  2FV2 A;  5SVZ A;  1F59 A;  3L6X A;  3ZIL A;  1M8X A;  4DB8 A;  2XA7 A;  2QMR A;  3L3Q A;  3A6P A;  2JKR A;  4U54 A;  3UL1 B;  3GQ2 A;  4A3V A;  2VGL A;  2NYL B;  3GVO A;  4P6Z G;  3BTR C;  4U5V A;  3GAE A;  2RU4 A;  1UN0 A;  3W3U A;  3Q5U A;  3UL0 B;  5KLR B;  5CL5 A;  4MFV A;  1Q1T C;  3RZ9 A;  2X1G F;  5CL9 A;  2F31 A;  4I8M A;  4UQI A;  1M5N S;  5CLD A;  3K4E A;  3RZX A;  3TT9 A;  3TPO A;  3OUX A;  1BK5 A;  3BWT A;  4FZD A;  4FDD A;  3FGA B;  1Z2C B;  3EG5 B;  1O6P A;  3QGB A;  3OUW A;  5BZV A;  3KND A;  3VLF A;  3VE6 A;  3EBB A;  2Z5N A;  3NOW A;  4IMI A;  3K5Z A;  1M1E A;  4JW2 B;  3WPT A;  4MZ6 E;  5D5K C;  2IE3 A;  3T7U A;  5HHG E;  4QMJ A;  4JW3 C;  4L4H A;  4HM9 A;  3WYF C;  4EVT A;  4V3Q A;  2PKG A;  5DN7 A;  5KL8 A;  3ZIN A;  1JDH A;  2OT8 A;  3ZIQ A;  5EKF A;  3TJZ B;  4I3N A;  1GCJ A;  1XQS A;  4CV5 B;  2H4M A;  4CBA A;  2NYM B;  5EKG A;  4NZW A;  4I37 A;  4LAC A;  1M8Y A;  4Y5J A;  5K6S A;  3UJ4 A;  3ODS A;  3UVU A;  3O4X A;  3JXZ A;  5CL8 A;  4TNM A;  2NPP A;  4RXH B;  3V6Y A;  4YK6 A;  4B18 A;  4IMJ A;  1IBR B;  3L3F X;  1B3U A;  5KLA A;  4MZ5 E;  3GS3 A;  2JKT B;  3LWW A;  3K64 A;  2X19 B;  3QGC A;  1W9C A;  4K92 A;  4R10 A;  4K6J A;  3K62 A;  4U5S A;  3ODR A;  5J3V A;  2YJY A;  1I7W A;  4DB6 A;  4I1E A;  4V3O A;  2XA7 B;  2QK1 A;  2NYL A;  4EVA A;  1EJY I;  3TPM A;  4CT6 B;  4EVP A;  4DJS A;  4D4E A;  5SWF A;  4OIH A;  3FEY C;  4H3H A;  4FFB C;  3DAD A;  2RU4 B;  2JAK A;  4PVZ A;  4RZP A;  1M8W A;  4B8J A;  5KLT B;  4E4V A;  4DBA A;  3L6Y A;  3IBV A;  5CL4 A;  3C2H A;  5H2X A;  1O6O A;  4PLR A;  4HNM A;  4CT7 B;  3OQS A;  1QGK A;  4I7I A;  4U5O A;  1TE4 A;  4XZR B;  3FGA A;  3GRL A;  1EE4 A;  5B56 A;  4R0Z A;  4FZF A;  3TJ3 A;  3FEX C;  5KL1 A;  2BNX A;  1LUJ A;  4L7M A;  2Z6G A;  4HXT A;  4CB8 A;  2Z6H A;  3LTJ A;  5SW9 A;  5CLC A;  3PSP A;  5CLA A;  2QNA A;  4JW2 A;  1T08 A;  4QMI A;  3ZIP A;  4U2X D;  5K9S A;  4I96 A;  4BPL A;  1HO8 A;  2GL7 A;  1LRV A;  5CLB A;  3Q0L A;  2IW3 A;  2QK2 A;  2OF3 A;  3C5W A;  4I6I A;  1W63 B;  2P8Q A;  2BCT A;  4YJL A;  3ZKV A;  4HTV A;  3V71 A;  2YNR A;  3NMX A;  3ZIK A;  5BZ1 A;  5HUY C;  3Q0S A;  5H2W A;  1IB2 A;  4I5N A;  5CL3 A;  4MFU A;  3IFQ A;  3TX7 A;  4DZS A;  2Z5K A;  2JDQ A;  1XM9 A;  4A3T A;  2NYM A;  4P6Z B;  1XQR A;  4U3J C;  4KZG A;  4V3R A;  3Q0N A;  5KUB A;  3C2G A;  3OBV A;  3GNI A;  4NEE A;  3QG9 A; 
#chains in the Genus database with same CATH homology
 1U6G C;  3NMZ A;  2Z5M A;  5FC8 E;  1UPK A;  3SLA A;  5HUW C;  3Q0O A;  3O2S A;  3UKW B;  3ZIR A;  2IAE A;  4BA3 A;  1WA5 C;  3Q0M A;  3PST A;  4UAE A;  3O2T A;  4EV9 A;  1UPL A;  2IWH A;  4I2Z A;  2JKT A;  4U5N A;  5AEI A;  4PLQ A;  4UAF B;  4YI0 C;  4FZA A;  3JXY A;  3SL9 A;  4I2S A;  4A0C A;  5LSW A;  4CRV B;  3BCT A;  4I5L A;  2JKR B;  5BZU A;  1EJL I;  2XOA A;  3OPB A;  2VGL B;  5E6Q B;  3Q0R A;  3V74 A;  3ZIO A;  2W3C A;  3AU3 A;  3UKY B;  4H3K A;  4JKQ A;  3EA5 B;  3VWA A;  3DW8 A;  4JLQ A;  5CL7 A;  1QGR A;  3UKZ B;  2IE4 A;  1TH1 A;  4R11 A;  3K49 A;  1BK6 A;  1G3J A;  4L4I A;  2C1M A;  4I0Y A;  2IX3 A;  3BSX A;  3BSB A;  3ND2 A;  5CTT A;  4PLS A;  2C1T A;  4I2W A;  1EE5 A;  4UQI B;  4D49 A;  3JY1 A;  4B8O A;  5EWP A;  4WV6 A;  2BKU B;  3K5Y A;  3JX7 A;  3Q0P A;  4QMH A;  3H3D X;  3QHE A;  2DB0 A;  3K7W A;  4DVG B;  1Q1S C;  1PJN B;  4GMO A;  4BQK A;  1I7X A;  3ZHP A;  4YJE A;  4CB9 A;  4GMN A;  1WA5 B;  1JPW A;  5JJA A;  3O2Q A;  3K5Q A;  2WTK A;  3K61 A;  3BX2 A;  3VLE A;  2Q5D A;  3NMW A;  3BVS A;  1W63 A;  4OO6 A;  2PF4 A;  3VLD A;  2YNS A;  4RV1 A;  4B8P A;  1V18 A;  4U5L A;  3Q0Q A;  3LTM A;  3WOZ A;  1JPP A;  4O27 A;  1Y2A C;  5BYM A;  1IQ1 C;  1M8Z A;  2Z5J A;  5BZ5 A;  3BX3 A;  4U58 A;  4FP7 A;  1UKL A;  4UAD A;  2Z5O A;  5CL6 A;  1PJM B;  3UKX B;  4ADY A;  4U5U A;  4G3A A;  4UWX A;  1OYZ A;  4DB9 A;  2NPP B;  4ZDU A;  1IAL A;  3GVT A;  3WOY A;  3QML C;  4CRU B;  3K7V A;  2BAP A;  3GB8 A;  4FQ3 A;  2IAE B;  1QBK B;  1QZ7 A;  5CLE A;  4EV8 A;  4YGX A;  2FV2 A;  5SVZ A;  1F59 A;  3L6X A;  3ZIL A;  1M8X A;  4DB8 A;  2XA7 A;  2QMR A;  3L3Q A;  3A6P A;  2JKR A;  4U54 A;  3UL1 B;  3GQ2 A;  4A3V A;  2VGL A;  2NYL B;  3GVO A;  4P6Z G;  3BTR C;  4U5V A;  3GAE A;  2RU4 A;  1UN0 A;  3W3U A;  3Q5U A;  3UL0 B;  5KLR B;  5CL5 A;  4MFV A;  1Q1T C;  3RZ9 A;  2X1G F;  5CL9 A;  2F31 A;  4I8M A;  4UQI A;  1M5N S;  5CLD A;  3K4E A;  3RZX A;  3TT9 A;  3TPO A;  3OUX A;  1BK5 A;  3BWT A;  4FZD A;  4FDD A;  3FGA B;  1Z2C B;  3EG5 B;  1O6P A;  3QGB A;  3OUW A;  5BZV A;  3KND A;  3VLF A;  3VE6 A;  3EBB A;  2Z5N A;  3NOW A;  4IMI A;  3K5Z A;  1M1E A;  4JW2 B;  3WPT A;  4MZ6 E;  5D5K C;  2IE3 A;  3T7U A;  5HHG E;  4QMJ A;  4JW3 C;  4L4H A;  4HM9 A;  3WYF C;  4EVT A;  4V3Q A;  2PKG A;  5DN7 A;  5KL8 A;  3ZIN A;  1JDH A;  2OT8 A;  3ZIQ A;  5EKF A;  3TJZ B;  4I3N A;  1GCJ A;  1XQS A;  4CV5 B;  2H4M A;  4CBA A;  2NYM B;  5EKG A;  4NZW A;  4I37 A;  4LAC A;  1M8Y A;  4Y5J A;  5K6S A;  3ODS A;  3UVU A;  3O4X A;  3JXZ A;  5CL8 A;  4TNM A;  2NPP A;  4RXH B;  3V6Y A;  4YK6 A;  4B18 A;  4IMJ A;  1IBR B;  3L3F X;  1B3U A;  5KLA A;  4MZ5 E;  3GS3 A;  2JKT B;  3LWW A;  3K64 A;  2X19 B;  3QGC A;  1W9C A;  4K92 A;  4R10 A;  4K6J A;  3K62 A;  4U5S A;  3ODR A;  5J3V A;  2YJY A;  1I7W A;  4DB6 A;  4I1E A;  4V3O A;  2XA7 B;  2QK1 A;  2NYL A;  4EVA A;  1EJY I;  3TPM A;  4CT6 B;  4EVP A;  4DJS A;  4D4E A;  5SWF A;  4OIH A;  3FEY C;  4H3H A;  4FFB C;  3DAD A;  2RU4 B;  2JAK A;  4PVZ A;  4RZP A;  1M8W A;  4B8J A;  5KLT B;  4E4V A;  4DBA A;  3L6Y A;  3IBV A;  5CL4 A;  3C2H A;  5H2X A;  1O6O A;  4PLR A;  4HNM A;  4CT7 B;  3OQS A;  1QGK A;  4I7I A;  4U5O A;  1TE4 A;  4XZR B;  3FGA A;  3GRL A;  1EE4 A;  5B56 A;  4R0Z A;  4FZF A;  3TJ3 A;  3FEX C;  5KL1 A;  2BNX A;  1LUJ A;  4L7M A;  2Z6G A;  4HXT A;  4CB8 A;  2Z6H A;  3LTJ A;  5SW9 A;  5CLC A;  3PSP A;  5CLA A;  2QNA A;  4JW2 A;  1T08 A;  4QMI A;  3ZIP A;  4U2X D;  5K9S A;  4I96 A;  4BPL A;  1HO8 A;  2GL7 A;  1LRV A;  5CLB A;  3Q0L A;  2IW3 A;  2QK2 A;  2OF3 A;  3C5W A;  4I6I A;  1W63 B;  2P8Q A;  2BCT A;  4YJL A;  3ZKV A;  4HTV A;  3V71 A;  2YNR A;  3NMX A;  3ZIK A;  5BZ1 A;  5HUY C;  3Q0S A;  5H2W A;  1IB2 A;  4I5N A;  5CL3 A;  4MFU A;  3IFQ A;  3TX7 A;  4DZS A;  2Z5K A;  2JDQ A;  1XM9 A;  4A3T A;  2NYM A;  4P6Z B;  1XQR A;  4U3J C;  4KZG A;  4V3R A;  3Q0N A;  5KUB A;  3C2G A;  3OBV A;  3GNI A;  4NEE A;  3QG9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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