4NEEA

Crystal structure of ap-2 alpha/simga2 complex bound to hiv-1 nef
Total Genus 133
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
388
structure length
385
Chain Sequence
GMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGLDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
pubmed doi rcsb
molecule tags Viral protein/protein transport
source organism Rattus norvegicus
molecule keywords AP-2 complex subunit sigma
total genus 133
structure length 385
sequence length 388
chains with identical sequence B, G, J
ec nomenclature
pdb deposition date 2013-10-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat Variant 4neeA00
3TPMA 2JKTA 3Q0SA 5BZ5A 3BTRC 4U5NA 2IWHA 4U5OA 1U6GC 3L3QA 3Q0RA 3IBVA 4RZPA 1EE5A 1I7WA 5JJAA 4E4VA 3K7VA 4MFUA 1M8WA 5E6QB 5DN7A 3DADA 2IAEA 4QMHA 4XZRB 4YI0C 2XA7A 3ND2A 3UKYB 4IMIA 4UAFB 2YJYA 4YJEA 4MFVA 4R10A 1M8YA 1TH1A 3ZIOA 1WA5C 1O6OA 3A6PA 4HXTA 3TJ3A 3OUXA 4H3KA 3RZXA 4V3OA 4RXHB 1QBKB 2P8QA 3QHEA 3ODSA 3PSPA 5KLTB 2IW3A 5AEIA 3O2TA 3ODRA 1QZ7A 2JKRA 2FV2A 3ZIPA 3K61A 1O6PA 4FDDA 3AU3A 3C5WA 4YGXA 3K7WA 3L3FX 4UADA 4UQIA 5HUYC 1IB2A 3BCTA 4PLSA 4EV9A 3GRLA 1M8XA 4B8JA 4UWXA 2QMRA 3O2QA 5KLRB 4U58A 5KL8A 1M5NS 4V3QA 5HHGE 4P6ZB 5BZUA 4YJLA 4I2WA 4B8PA 2C1MA 4K6JA 2YNRA 5K9SA 3K5YA 5CTTA 4DVGB 3T7UA 4FZDA 4I5NA 3EG5B 1UKLA 3OPBA 3V74A 3ZIRA 2RU4A 2QNAA 2NYMB 3Q0PA 4NZWA 5K6SA 3V6YA 4H3HA 5EWPA 5KLAA 2NPPA 4U3JC 2IE3A 3W3UA 3UKZB 4O27A 3V71A 4BPLA 3WOYA 4U54A 4QMIA 2DB0A 1LUJA 4ZDUA 3OUWA 4I2ZA 4YK6A 2F31A 1IQ1C 4U5VA 4PVZA 3UL1B 1LRVA 4RV1A 3VE6A 5SVZA 1EJYI 3K62A 1EJLI 1HO8A 4ADYA 5B56A 4DB6A 1F59A 1UPLA 3QMLC 4OIHA 1XQRA 4MZ6E 1QGKA 4NEEA 3IFQA 3NMXA 5D5KC 1W63B 3NOWA 5J3VA 4LACA 3ZHPA 3K5QA 2VGLB 1Q1TC 5H2XA 4A0CA 3RZ9A 1Z2CB 3DW8A 3H3DX 4CB9A 3GNIA 5SWFA 5BYMA 1G3JA 2Z5MA 4DB8A 4KZGA 3Q0MA 4JW2B 1BK6A 1Y2AC 4TNMA 1V18A 2PF4A 2NYLB 4FZFA 5LSWA 1PJNB 4B8OA 3FGAB 1Q1SC 5BZVA 5FC8E 1EE4A 3K64A 3GB8A 4CRUB 4CT6B 2OF3A 2YNSA 2OT8A 3UVUA 4I5LA 3UKXB 4CT7B 1T08A 3Q0QA 2JKTB 2Z5JA 4P6ZG 1OYZA 4U5UA 2BCTA 1WA5B 1UPKA 3FEXC 2C1TA 2IE4A 4U5SA 4L7MA 2JDQA 4EVPA 4GMOA 4HTVA 1I7XA 2IAEB 1W9CA 1XM9A 2NYMA 4JLQA 2XA7B 2W3CA 3PSTA 4CRVB 4EVAA 5EKFA 3C2GA 3FEYC 3K5ZA 3KNDA 4HM9A 4PLQA 3Q0NA 2Q5DA 4HNMA 3TX7A 2IX3A 3Q0OA 3OQSA 2X1GF 4R0ZA 2H4MA 3K4EA 5SW9A 2JKRB 2WTKA 4Y5JA 4DZSA 3EA5B 3L6XA 4D4EA 3L6YA 3Q5UA 3GVOA 1B3UA 1JDHA 4UQIB 1XQSA 4EV8A 3TPOA 2X19B 3QGBA 2Z5NA 3UL0B 1M8ZA 5HUWC 4OO6A 4CB8A 3ZIQA 5EKGA 4D49A 3ZINA 4K92A 3BX3A 4V3RA 4B18A 4FQ3A 4CBAA 3VWAA 2RU4B 4CV5B 3UKWB 3TT9A 2Z6GA 2JAKA 1W63A 2BAPA 4U5LA 5KL1A 4IMJA 4WV6A 1IALA 2NPPB 2Z6HA 2Z5OA 4GMNA 2VGLA 3O4XA 4UAEA 3K49A 4BA3A 3BSXA 3C2HA 1PJMB 4MZ5E 4DBAA 2PKGA 2GL7A 3NMWA 3GS3A 3LTMA 3O2SA 3LWWA 3QG9A 4EVTA 3EBBA 3BX2A 1IBRB 4FZAA 3LTJA 1JPPA 3Q0LA 1GCJA 3OBVA 3GAEA 2NYLA 4FFBC 4G3AA 3QGCA 3BWTA 4BQKA 3WYFC 3FGAA 3TJZB 1M1EA 1QGRA 1JPWA 1BK5A 4R11A 2QK2A 4DB9A 3BSBA 3NMZA 2BKUB 3GQ2A 2QK1A 1UN0A 4QMJA 5H2WA 4DJSA 3ZKVA 3GVTA 4PLRA 5BZ1A 2BNXA 3WPTA 3WOZA 2Z5KA
chains in the Genus database with same CATH superfamily
3TPMA 1LSHA 2JKTA 3Q0SA 5BZ5A 3BTRC 4JKQA 4U5NA 2IWHA 4U5OA 1U6GC 3VLFA 3L3QA 3Q0RA 4A3TA 3IBVA 4RZPA 1EE5A 1I7WA 4I1EA 5JJAA 4E4VA 3K7VA 4MFUA 1M8WA 5E6QB 5DN7A 3DADA 2IAEA 4QMHA 4XZRB 3VLEA 3UKYB 4YI0C 2XA7A 3ND2A 4I0YA 4IMIA 4UAFB 2YJYA 4YJEA 4MFVA 4R10A 1M8YA 1TH1A 3ZIOA 1WA5C 1O6OA 3A6PA 4HXTA 3TJ3A 4L4HA 3OUXA 4H3KA 3RZXA 4V3OA 4RXHB 1QBKB 2P8QA 3QHEA 3ODSA 3PSPA 2XOAA 5KLTB 2IW3A 5AEIA 3O2TA 3ODRA 1QZ7A 2JKRA 2FV2A 3ZIPA 3K61A 1O6PA 4FDDA 3AU3A 3C5WA 4YGXA 3K7WA 4UQIA 4UADA 3L3FX 5HUYC 1IB2A 3BCTA 4PLSA 4I7IA 3GRLA 4EV9A 1M8XA 3BVSA 4B8JA 4UWXA 2QMRA 3O2QA 5KLRB 4U58A 5KL8A 1M5NS 4V3QA 5HHGE 4P6ZB 5BZUA 4YJLA 4I2WA 4B8PA 2C1MA 4K6JA 2YNRA 5K9SA 3K5YA 5CTTA 4DVGB 3T7UA 4FZDA 4I5NA 3EG5B 1UKLA 3OPBA 3V74A 2RU4A 2QNAA 3ZIRA 2NYMB 4FP7A 3Q0PA 5CL8A 3ZILA 4NZWA 4L4IA 5CL4A 5K6SA 3V6YA 4H3HA 5EWPA 1TE4A 5KLAA 2NPPA 4U3JC 2IE3A 3W3UA 3UKZB 4O27A 3V71A 4BPLA 3WOYA 4U54A 5CL9A 4QMIA 2DB0A 1LUJA 4ZDUA 3OUWA 4I2ZA 4YK6A 2F31A 1IQ1C 4U5VA 4PVZA 3UL1B 5CL5A 1LRVA 4RV1A 3VE6A 5SVZA 1EJYI 3K62A 1EJLI 1HO8A 4ADYA 3JX7A 5B56A 4DB6A 1F59A 1UPLA 3QMLC 4OIHA 1XQRA 5CLDA 4MZ6E 1QGKA 4NEEA 5CL6A 3IFQA 3NMXA 3VLDA 5D5KC 1W63B 3NOWA 5J3VA 4I3NA 4LACA 3ZHPA 3K5QA 2VGLB 1Q1TC 5H2XA 4A0CA 3RZ9A 1Z2CB 3DW8A 3H3DX 4CB9A 3GNIA 5SWFA 5BYMA 1G3JA 2Z5MA 4DB8A 4A3VA 4KZGA 3Q0MA 4JW2B 1BK6A 1Y2AC 4TNMA 1V18A 2PF4A 2NYLB 4FZFA 5CLCA 5LSWA 1PJNB 4B8OA 3FGAB 3SL9A 1Q1SC 5BZVA 3JXZA 5FC8E 1EE4A 3K64A 3GB8A 4CRUB 4CT6B 2OF3A 2YNSA 2OT8A 3UVUA 4I5LA 3UKXB 4CT7B 1T08A 3Q0QA 2JKTB 2Z5JA 4P6ZG 1OYZA 4U5UA 2BCTA 1WA5B 4I96A 1UPKA 3FEXC 2C1TA 2IE4A 4U5SA 3JXYA 3SLAA 4L7MA 2JDQA 4EVPA 4GMOA 5CL7A 4HTVA 1I7XA 3T8SA 2IAEB 1W9CA 1XM9A 2NYMA 4JLQA 2XA7B 2W3CA 3PSTA 4CRVB 4EVAA 5EKFA 3C2GA 3FEYC 3K5ZA 3KNDA 4HM9A 4I2SA 4PLQA 3Q0NA 4I37A 2Q5DA 3UJ4A 4HNMA 3TX7A 2IX3A 3Q0OA 3OQSA 2X1GF 4R0ZA 2H4MA 3K4EA 5SW9A 2JKRB 2WTKA 4Y5JA 5CL3A 4DZSA 3EA5B 3L6XA 4D4EA 3L6YA 3Q5UA 3GVOA 1B3UA 1JDHA 4UQIB 1XQSA 4EV8A 4JW3C 3TPOA 2X19B 3QGBA 5CLBA 3ZIKA 2Z5NA 3UL0B 1N4KA 1M8ZA 5HUWC 4OO6A 4CB8A 3ZIQA 5EKGA 4D49A 3ZINA 4K92A 3BX3A 4V3RA 4B18A 4FQ3A 4CBAA 3VWAA 2RU4B 4CV5B 3UKWB 3TT9A 2Z6GA 2JAKA 1W63A 2BAPA 5CLAA 4U5LA 5KL1A 4IMJA 4WV6A 1IALA 2NPPB 2Z6HA 5KUBA 2Z5OA 4GMNA 2VGLA 3O4XA 5CLEA 4UAEA 3K49A 4BA3A 3BSXA 3C2HA 1PJMB 4MZ5E 4DBAA 2PKGA 2GL7A 3NMWA 3GS3A 3LTMA 3O2SA 3LWWA 3QG9A 4JW2A 4EVTA 3EBBA 3BX2A 1IBRB 4FZAA 3LTJA 3JY1A 1JPPA 3Q0LA 1GCJA 3OBVA 3GAEA 2NYLA 4FFBC 4G3AA 3QGCA 4U2XD 3BWTA 4BQKA 3WYFC 3FGAA 3TJZB 1M1EA 4I6IA 1QGRA 1JPWA 1BK5A 4R11A 2QK2A 3UJ0A 4DB9A 3BSBA 3NMZA 2BKUB 3GQ2A 2QK1A 1UN0A 4QMJA 5H2WA 4DJSA 3ZKVA 3GVTA 4I8MA 4PLRA 5BZ1A 2BNXA 3WPTA 3WOZA 2Z5KA
chains in the Genus database with same CATH topology
3TPMA 2JKTA 3Q0SA 5BZ5A 3BTRC 4JKQA 4U5NA 2IWHA 4U5OA 1U6GC 3VLFA 3L3QA 3Q0RA 4A3TA 3IBVA 4RZPA 1EE5A 1I7WA 4I1EA 5JJAA 4E4VA 3K7VA 4MFUA 1M8WA 5E6QB 5DN7A 3DADA 2IAEA 4QMHA 4XZRB 3VLEA 3UKYB 4YI0C 2XA7A 3ND2A 4I0YA 4IMIA 4UAFB 2YJYA 4YJEA 4MFVA 4R10A 1M8YA 1TH1A 3ZIOA 1WA5C 1O6OA 3A6PA 4HXTA 3TJ3A 4L4HA 3OUXA 4H3KA 3RZXA 4V3OA 4RXHB 1QBKB 2P8QA 3QHEA 3ODSA 3PSPA 2XOAA 5KLTB 2IW3A 5AEIA 3O2TA 3ODRA 1QZ7A 2JKRA 2FV2A 3ZIPA 3K61A 1O6PA 4FDDA 3AU3A 3C5WA 4YGXA 3K7WA 4UQIA 4UADA 3L3FX 5HUYC 1IB2A 3BCTA 4PLSA 4I7IA 3GRLA 4EV9A 1M8XA 3BVSA 4B8JA 4UWXA 2QMRA 3O2QA 5KLRB 4U58A 5KL8A 1M5NS 4V3QA 5HHGE 4P6ZB 5BZUA 4YJLA 4I2WA 4B8PA 2C1MA 4K6JA 2YNRA 5K9SA 3K5YA 5CTTA 4DVGB 3T7UA 4FZDA 4I5NA 3EG5B 1UKLA 3OPBA 3V74A 2RU4A 2QNAA 3ZIRA 2NYMB 4FP7A 3Q0PA 5CL8A 3ZILA 4NZWA 4L4IA 5CL4A 5K6SA 3V6YA 4H3HA 5EWPA 1TE4A 5KLAA 2NPPA 4U3JC 2IE3A 3W3UA 3UKZB 4O27A 3V71A 4BPLA 3WOYA 4U54A 5CL9A 4QMIA 2DB0A 1LUJA 4ZDUA 3OUWA 4I2ZA 4YK6A 2F31A 1IQ1C 4U5VA 4PVZA 3UL1B 5CL5A 1LRVA 4RV1A 3VE6A 5SVZA 1EJYI 3K62A 1EJLI 1HO8A 4ADYA 3JX7A 5B56A 4DB6A 1F59A 1UPLA 3QMLC 4OIHA 1XQRA 5CLDA 4MZ6E 1QGKA 4NEEA 5CL6A 3IFQA 3NMXA 3VLDA 5D5KC 1W63B 3NOWA 5J3VA 4I3NA 4LACA 3ZHPA 3K5QA 2VGLB 1Q1TC 5H2XA 4A0CA 3RZ9A 1Z2CB 3DW8A 3H3DX 4CB9A 3GNIA 5SWFA 5BYMA 1G3JA 2Z5MA 4DB8A 4A3VA 4KZGA 3Q0MA 4JW2B 1BK6A 1Y2AC 4TNMA 1V18A 2PF4A 2NYLB 4FZFA 5CLCA 5LSWA 1PJNB 4B8OA 3FGAB 3SL9A 1Q1SC 5BZVA 3JXZA 5FC8E 1EE4A 3K64A 3GB8A 4CRUB 4CT6B 2OF3A 2YNSA 2OT8A 3UVUA 4I5LA 3UKXB 4CT7B 1T08A 3Q0QA 2JKTB 2Z5JA 4P6ZG 1OYZA 4U5UA 2BCTA 1WA5B 4I96A 1UPKA 3FEXC 2C1TA 2IE4A 4U5SA 3JXYA 3SLAA 4L7MA 2JDQA 4EVPA 4GMOA 5CL7A 4HTVA 1I7XA 2IAEB 1W9CA 1XM9A 2NYMA 4JLQA 2XA7B 2W3CA 3PSTA 4CRVB 4EVAA 5EKFA 3C2GA 3FEYC 3K5ZA 3KNDA 4HM9A 4I2SA 4PLQA 3Q0NA 4I37A 2Q5DA 4HNMA 3TX7A 2IX3A 3Q0OA 3OQSA 2X1GF 4R0ZA 2H4MA 3K4EA 5SW9A 2JKRB 2WTKA 4Y5JA 5CL3A 4DZSA 3EA5B 3L6XA 4D4EA 3L6YA 3Q5UA 3GVOA 1B3UA 1JDHA 4UQIB 1XQSA 4EV8A 4JW3C 3TPOA 2X19B 3QGBA 5CLBA 3ZIKA 2Z5NA 3UL0B 1M8ZA 5HUWC 4OO6A 4CB8A 3ZIQA 5EKGA 4D49A 3ZINA 4K92A 3BX3A 4V3RA 4B18A 4FQ3A 4CBAA 3VWAA 2RU4B 4CV5B 3UKWB 3TT9A 2Z6GA 2JAKA 1W63A 2BAPA 5CLAA 4U5LA 5KL1A 4IMJA 4WV6A 1IALA 2NPPB 2Z6HA 5KUBA 2Z5OA 4GMNA 2VGLA 3O4XA 5CLEA 4UAEA 3K49A 4BA3A 3BSXA 3C2HA 1PJMB 4MZ5E 4DBAA 2PKGA 2GL7A 3NMWA 3GS3A 3LTMA 3O2SA 3LWWA 3QG9A 4JW2A 4EVTA 3EBBA 3BX2A 1IBRB 4FZAA 3LTJA 3JY1A 1JPPA 3Q0LA 1GCJA 3OBVA 3GAEA 2NYLA 4FFBC 4G3AA 3QGCA 4U2XD 3BWTA 4BQKA 3WYFC 3FGAA 3TJZB 1M1EA 4I6IA 1QGRA 1JPWA 1BK5A 4R11A 2QK2A 4DB9A 3BSBA 3NMZA 2BKUB 3GQ2A 2QK1A 1UN0A 4QMJA 5H2WA 4DJSA 3ZKVA 3GVTA 4I8MA 4PLRA 5BZ1A 2BNXA 3WPTA 3WOZA 2Z5KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TPM A;  2JKT A;  3Q0S A;  5BZ5 A;  3BTR C;  4U5N A;  2IWH A;  4U5O A;  1U6G C;  3L3Q A;  3Q0R A;  3IBV A;  4RZP A;  1EE5 A;  1I7W A;  5JJA A;  4E4V A;  3K7V A;  4MFU A;  1M8W A;  5E6Q B;  5DN7 A;  3DAD A;  2IAE A;  4QMH A;  4XZR B;  4YI0 C;  2XA7 A;  3ND2 A;  3UKY B;  4IMI A;  4UAF B;  2YJY A;  4YJE A;  4MFV A;  4R10 A;  1M8Y A;  1TH1 A;  3ZIO A;  1WA5 C;  1O6O A;  3A6P A;  4HXT A;  3TJ3 A;  3OUX A;  4H3K A;  3RZX A;  4V3O A;  4RXH B;  1QBK B;  2P8Q A;  3QHE A;  3ODS A;  3PSP A;  5KLT B;  2IW3 A;  5AEI A;  3O2T A;  3ODR A;  1QZ7 A;  2JKR A;  2FV2 A;  3ZIP A;  3K61 A;  1O6P A;  4FDD A;  3AU3 A;  3C5W A;  4YGX A;  3K7W A;  3L3F X;  4UAD A;  4UQI A;  5HUY C;  1IB2 A;  3BCT A;  4PLS A;  4EV9 A;  3GRL A;  1M8X A;  4B8J A;  4UWX A;  2QMR A;  3O2Q A;  5KLR B;  4U58 A;  5KL8 A;  1M5N S;  4V3Q A;  5HHG E;  4P6Z B;  5BZU A;  4YJL A;  4I2W A;  4B8P A;  2C1M A;  4K6J A;  2YNR A;  5K9S A;  3K5Y A;  5CTT A;  4DVG B;  3T7U A;  4FZD A;  4I5N A;  3EG5 B;  1UKL A;  3OPB A;  3V74 A;  3ZIR A;  2RU4 A;  2QNA A;  2NYM B;  3Q0P A;  4NZW A;  5K6S A;  3V6Y A;  4H3H A;  5EWP A;  5KLA A;  2NPP A;  4U3J C;  2IE3 A;  3W3U A;  3UKZ B;  4O27 A;  3V71 A;  4BPL A;  3WOY A;  4U54 A;  4QMI A;  2DB0 A;  1LUJ A;  4ZDU A;  3OUW A;  4I2Z A;  4YK6 A;  2F31 A;  1IQ1 C;  4U5V A;  4PVZ A;  3UL1 B;  1LRV A;  4RV1 A;  3VE6 A;  5SVZ A;  1EJY I;  3K62 A;  1EJL I;  1HO8 A;  4ADY A;  5B56 A;  4DB6 A;  1F59 A;  1UPL A;  3QML C;  4OIH A;  1XQR A;  4MZ6 E;  1QGK A;  4NEE A;  3IFQ A;  3NMX A;  5D5K C;  1W63 B;  3NOW A;  5J3V A;  4LAC A;  3ZHP A;  3K5Q A;  2VGL B;  1Q1T C;  5H2X A;  4A0C A;  3RZ9 A;  1Z2C B;  3DW8 A;  3H3D X;  4CB9 A;  3GNI A;  5SWF A;  5BYM A;  1G3J A;  2Z5M A;  4DB8 A;  4KZG A;  3Q0M A;  4JW2 B;  1BK6 A;  1Y2A C;  4TNM A;  1V18 A;  2PF4 A;  2NYL B;  4FZF A;  5LSW A;  1PJN B;  4B8O A;  3FGA B;  1Q1S C;  5BZV A;  5FC8 E;  1EE4 A;  3K64 A;  3GB8 A;  4CRU B;  4CT6 B;  2OF3 A;  2YNS A;  2OT8 A;  3UVU A;  4I5L A;  3UKX B;  4CT7 B;  1T08 A;  3Q0Q A;  2JKT B;  2Z5J A;  4P6Z G;  1OYZ A;  4U5U A;  2BCT A;  1WA5 B;  1UPK A;  3FEX C;  2C1T A;  2IE4 A;  4U5S A;  4L7M A;  2JDQ A;  4EVP A;  4GMO A;  4HTV A;  1I7X A;  2IAE B;  1W9C A;  1XM9 A;  2NYM A;  4JLQ A;  2XA7 B;  2W3C A;  3PST A;  4CRV B;  4EVA A;  5EKF A;  3C2G A;  3FEY C;  3K5Z A;  3KND A;  4HM9 A;  4PLQ A;  3Q0N A;  2Q5D A;  4HNM A;  3TX7 A;  2IX3 A;  3Q0O A;  3OQS A;  2X1G F;  4R0Z A;  2H4M A;  3K4E A;  5SW9 A;  2JKR B;  2WTK A;  4Y5J A;  4DZS A;  3EA5 B;  3L6X A;  4D4E A;  3L6Y A;  3Q5U A;  3GVO A;  1B3U A;  1JDH A;  4UQI B;  1XQS A;  4EV8 A;  3TPO A;  2X19 B;  3QGB A;  2Z5N A;  3UL0 B;  1M8Z A;  5HUW C;  4OO6 A;  4CB8 A;  3ZIQ A;  5EKG A;  4D49 A;  3ZIN A;  4K92 A;  3BX3 A;  4V3R A;  4B18 A;  4FQ3 A;  4CBA A;  3VWA A;  2RU4 B;  4CV5 B;  3UKW B;  3TT9 A;  2Z6G A;  2JAK A;  1W63 A;  2BAP A;  4U5L A;  5KL1 A;  4IMJ A;  4WV6 A;  1IAL A;  2NPP B;  2Z6H A;  2Z5O A;  4GMN A;  2VGL A;  3O4X A;  4UAE A;  3K49 A;  4BA3 A;  3BSX A;  3C2H A;  1PJM B;  4MZ5 E;  4DBA A;  2PKG A;  2GL7 A;  3NMW A;  3GS3 A;  3LTM A;  3O2S A;  3LWW A;  3QG9 A;  4EVT A;  3EBB A;  3BX2 A;  1IBR B;  4FZA A;  3LTJ A;  1JPP A;  3Q0L A;  1GCJ A;  3OBV A;  3GAE A;  2NYL A;  4FFB C;  4G3A A;  3QGC A;  3BWT A;  4BQK A;  3WYF C;  3FGA A;  3TJZ B;  1M1E A;  1QGR A;  1JPW A;  1BK5 A;  4R11 A;  2QK2 A;  4DB9 A;  3BSB A;  3NMZ A;  2BKU B;  3GQ2 A;  2QK1 A;  1UN0 A;  4QMJ A;  5H2W A;  4DJS A;  3ZKV A;  3GVT A;  4PLR A;  5BZ1 A;  2BNX A;  3WPT A;  3WOZ A;  2Z5K A; 
#chains in the Genus database with same CATH topology
 3TPM A;  1LSH A;  2JKT A;  3Q0S A;  5BZ5 A;  3BTR C;  4JKQ A;  4U5N A;  2IWH A;  4U5O A;  1U6G C;  3VLF A;  3L3Q A;  3Q0R A;  4A3T A;  3IBV A;  4RZP A;  1EE5 A;  1I7W A;  4I1E A;  5JJA A;  4E4V A;  3K7V A;  4MFU A;  1M8W A;  5E6Q B;  5DN7 A;  3DAD A;  2IAE A;  4QMH A;  4XZR B;  3VLE A;  3UKY B;  4YI0 C;  2XA7 A;  3ND2 A;  4I0Y A;  4IMI A;  4UAF B;  2YJY A;  4YJE A;  4MFV A;  4R10 A;  1M8Y A;  1TH1 A;  3ZIO A;  1WA5 C;  1O6O A;  3A6P A;  4HXT A;  3TJ3 A;  4L4H A;  3OUX A;  4H3K A;  3RZX A;  4V3O A;  4RXH B;  1QBK B;  2P8Q A;  3QHE A;  3ODS A;  3PSP A;  2XOA A;  5KLT B;  2IW3 A;  5AEI A;  3O2T A;  3ODR A;  1QZ7 A;  2JKR A;  2FV2 A;  3ZIP A;  3K61 A;  1O6P A;  4FDD A;  3AU3 A;  3C5W A;  4YGX A;  3K7W A;  4UQI A;  4UAD A;  3L3F X;  5HUY C;  1IB2 A;  3BCT A;  4PLS A;  4I7I A;  3GRL A;  4EV9 A;  1M8X A;  3BVS A;  4B8J A;  4UWX A;  2QMR A;  3O2Q A;  5KLR B;  4U58 A;  5KL8 A;  1M5N S;  4V3Q A;  5HHG E;  4P6Z B;  5BZU A;  4YJL A;  4I2W A;  4B8P A;  2C1M A;  4K6J A;  2YNR A;  5K9S A;  3K5Y A;  5CTT A;  4DVG B;  3T7U A;  4FZD A;  4I5N A;  3EG5 B;  1UKL A;  3OPB A;  3V74 A;  2RU4 A;  2QNA A;  3ZIR A;  2NYM B;  4FP7 A;  3Q0P A;  5CL8 A;  3ZIL A;  4NZW A;  4L4I A;  5CL4 A;  5K6S A;  3V6Y A;  4H3H A;  5EWP A;  1TE4 A;  5KLA A;  2NPP A;  4U3J C;  2IE3 A;  3W3U A;  3UKZ B;  4O27 A;  3V71 A;  4BPL A;  3WOY A;  4U54 A;  5CL9 A;  4QMI A;  2DB0 A;  1LUJ A;  4ZDU A;  3OUW A;  4I2Z A;  4YK6 A;  2F31 A;  1IQ1 C;  4U5V A;  4PVZ A;  3UL1 B;  5CL5 A;  1LRV A;  4RV1 A;  3VE6 A;  5SVZ A;  1EJY I;  3K62 A;  1EJL I;  1HO8 A;  4ADY A;  3JX7 A;  5B56 A;  4DB6 A;  1F59 A;  1UPL A;  3QML C;  4OIH A;  1XQR A;  5CLD A;  4MZ6 E;  1QGK A;  4NEE A;  5CL6 A;  3IFQ A;  3NMX A;  3VLD A;  5D5K C;  1W63 B;  3NOW A;  5J3V A;  4I3N A;  4LAC A;  3ZHP A;  3K5Q A;  2VGL B;  1Q1T C;  5H2X A;  4A0C A;  3RZ9 A;  1Z2C B;  3DW8 A;  3H3D X;  4CB9 A;  3GNI A;  5SWF A;  5BYM A;  1G3J A;  2Z5M A;  4DB8 A;  4A3V A;  4KZG A;  3Q0M A;  4JW2 B;  1BK6 A;  1Y2A C;  4TNM A;  1V18 A;  2PF4 A;  2NYL B;  4FZF A;  5CLC A;  5LSW A;  1PJN B;  4B8O A;  3FGA B;  3SL9 A;  1Q1S C;  5BZV A;  3JXZ A;  5FC8 E;  1EE4 A;  3K64 A;  3GB8 A;  4CRU B;  4CT6 B;  2OF3 A;  2YNS A;  2OT8 A;  3UVU A;  4I5L A;  3UKX B;  4CT7 B;  1T08 A;  3Q0Q A;  2JKT B;  2Z5J A;  4P6Z G;  1OYZ A;  4U5U A;  2BCT A;  1WA5 B;  4I96 A;  1UPK A;  3FEX C;  2C1T A;  2IE4 A;  4U5S A;  3JXY A;  3SLA A;  4L7M A;  2JDQ A;  4EVP A;  4GMO A;  5CL7 A;  4HTV A;  1I7X A;  3T8S A;  2IAE B;  1W9C A;  1XM9 A;  2NYM A;  4JLQ A;  2XA7 B;  2W3C A;  3PST A;  4CRV B;  4EVA A;  5EKF A;  3C2G A;  3FEY C;  3K5Z A;  3KND A;  4HM9 A;  4I2S A;  4PLQ A;  3Q0N A;  4I37 A;  2Q5D A;  3UJ4 A;  4HNM A;  3TX7 A;  2IX3 A;  3Q0O A;  3OQS A;  2X1G F;  4R0Z A;  2H4M A;  3K4E A;  5SW9 A;  2JKR B;  2WTK A;  4Y5J A;  5CL3 A;  4DZS A;  3EA5 B;  3L6X A;  4D4E A;  3L6Y A;  3Q5U A;  3GVO A;  1B3U A;  1JDH A;  4UQI B;  1XQS A;  4EV8 A;  4JW3 C;  3TPO A;  2X19 B;  3QGB A;  5CLB A;  3ZIK A;  2Z5N A;  3UL0 B;  1N4K A;  1M8Z A;  5HUW C;  4OO6 A;  4CB8 A;  3ZIQ A;  5EKG A;  4D49 A;  3ZIN A;  4K92 A;  3BX3 A;  4V3R A;  4B18 A;  4FQ3 A;  4CBA A;  3VWA A;  2RU4 B;  4CV5 B;  3UKW B;  3TT9 A;  2Z6G A;  2JAK A;  1W63 A;  2BAP A;  5CLA A;  4U5L A;  5KL1 A;  4IMJ A;  4WV6 A;  1IAL A;  2NPP B;  2Z6H A;  5KUB A;  2Z5O A;  4GMN A;  2VGL A;  3O4X A;  5CLE A;  4UAE A;  3K49 A;  4BA3 A;  3BSX A;  3C2H A;  1PJM B;  4MZ5 E;  4DBA A;  2PKG A;  2GL7 A;  3NMW A;  3GS3 A;  3LTM A;  3O2S A;  3LWW A;  3QG9 A;  4JW2 A;  4EVT A;  3EBB A;  3BX2 A;  1IBR B;  4FZA A;  3LTJ A;  3JY1 A;  1JPP A;  3Q0L A;  1GCJ A;  3OBV A;  3GAE A;  2NYL A;  4FFB C;  4G3A A;  3QGC A;  4U2X D;  3BWT A;  4BQK A;  3WYF C;  3FGA A;  3TJZ B;  1M1E A;  4I6I A;  1QGR A;  1JPW A;  1BK5 A;  4R11 A;  2QK2 A;  3UJ0 A;  4DB9 A;  3BSB A;  3NMZ A;  2BKU B;  3GQ2 A;  2QK1 A;  1UN0 A;  4QMJ A;  5H2W A;  4DJS A;  3ZKV A;  3GVT A;  4I8M A;  4PLR A;  5BZ1 A;  2BNX A;  3WPT A;  3WOZ A;  2Z5K A; 
#chains in the Genus database with same CATH homology
 3TPM A;  2JKT A;  3Q0S A;  5BZ5 A;  3BTR C;  4JKQ A;  4U5N A;  2IWH A;  4U5O A;  1U6G C;  3VLF A;  3L3Q A;  3Q0R A;  4A3T A;  3IBV A;  4RZP A;  1EE5 A;  1I7W A;  4I1E A;  5JJA A;  4E4V A;  3K7V A;  4MFU A;  1M8W A;  5E6Q B;  5DN7 A;  3DAD A;  2IAE A;  4QMH A;  4XZR B;  3VLE A;  3UKY B;  4YI0 C;  2XA7 A;  3ND2 A;  4I0Y A;  4IMI A;  4UAF B;  2YJY A;  4YJE A;  4MFV A;  4R10 A;  1M8Y A;  1TH1 A;  3ZIO A;  1WA5 C;  1O6O A;  3A6P A;  4HXT A;  3TJ3 A;  4L4H A;  3OUX A;  4H3K A;  3RZX A;  4V3O A;  4RXH B;  1QBK B;  2P8Q A;  3QHE A;  3ODS A;  3PSP A;  2XOA A;  5KLT B;  2IW3 A;  5AEI A;  3O2T A;  3ODR A;  1QZ7 A;  2JKR A;  2FV2 A;  3ZIP A;  3K61 A;  1O6P A;  4FDD A;  3AU3 A;  3C5W A;  4YGX A;  3K7W A;  4UQI A;  4UAD A;  3L3F X;  5HUY C;  1IB2 A;  3BCT A;  4PLS A;  4I7I A;  3GRL A;  4EV9 A;  1M8X A;  3BVS A;  4B8J A;  4UWX A;  2QMR A;  3O2Q A;  5KLR B;  4U58 A;  5KL8 A;  1M5N S;  4V3Q A;  5HHG E;  4P6Z B;  5BZU A;  4YJL A;  4I2W A;  4B8P A;  2C1M A;  4K6J A;  2YNR A;  5K9S A;  3K5Y A;  5CTT A;  4DVG B;  3T7U A;  4FZD A;  4I5N A;  3EG5 B;  1UKL A;  3OPB A;  3V74 A;  2RU4 A;  2QNA A;  3ZIR A;  2NYM B;  4FP7 A;  3Q0P A;  5CL8 A;  3ZIL A;  4NZW A;  4L4I A;  5CL4 A;  5K6S A;  3V6Y A;  4H3H A;  5EWP A;  1TE4 A;  5KLA A;  2NPP A;  4U3J C;  2IE3 A;  3W3U A;  3UKZ B;  4O27 A;  3V71 A;  4BPL A;  3WOY A;  4U54 A;  5CL9 A;  4QMI A;  2DB0 A;  1LUJ A;  4ZDU A;  3OUW A;  4I2Z A;  4YK6 A;  2F31 A;  1IQ1 C;  4U5V A;  4PVZ A;  3UL1 B;  5CL5 A;  1LRV A;  4RV1 A;  3VE6 A;  5SVZ A;  1EJY I;  3K62 A;  1EJL I;  1HO8 A;  4ADY A;  3JX7 A;  5B56 A;  4DB6 A;  1F59 A;  1UPL A;  3QML C;  4OIH A;  1XQR A;  5CLD A;  4MZ6 E;  1QGK A;  4NEE A;  5CL6 A;  3IFQ A;  3NMX A;  3VLD A;  5D5K C;  1W63 B;  3NOW A;  5J3V A;  4I3N A;  4LAC A;  3ZHP A;  3K5Q A;  2VGL B;  1Q1T C;  5H2X A;  4A0C A;  3RZ9 A;  1Z2C B;  3DW8 A;  3H3D X;  4CB9 A;  3GNI A;  5SWF A;  5BYM A;  1G3J A;  2Z5M A;  4DB8 A;  4A3V A;  4KZG A;  3Q0M A;  4JW2 B;  1BK6 A;  1Y2A C;  4TNM A;  1V18 A;  2PF4 A;  2NYL B;  4FZF A;  5CLC A;  5LSW A;  1PJN B;  4B8O A;  3FGA B;  3SL9 A;  1Q1S C;  5BZV A;  3JXZ A;  5FC8 E;  1EE4 A;  3K64 A;  3GB8 A;  4CRU B;  4CT6 B;  2OF3 A;  2YNS A;  2OT8 A;  3UVU A;  4I5L A;  3UKX B;  4CT7 B;  1T08 A;  3Q0Q A;  2JKT B;  2Z5J A;  4P6Z G;  1OYZ A;  4U5U A;  2BCT A;  1WA5 B;  4I96 A;  1UPK A;  3FEX C;  2C1T A;  2IE4 A;  4U5S A;  3JXY A;  3SLA A;  4L7M A;  2JDQ A;  4EVP A;  4GMO A;  5CL7 A;  4HTV A;  1I7X A;  2IAE B;  1W9C A;  1XM9 A;  2NYM A;  4JLQ A;  2XA7 B;  2W3C A;  3PST A;  4CRV B;  4EVA A;  5EKF A;  3C2G A;  3FEY C;  3K5Z A;  3KND A;  4HM9 A;  4I2S A;  4PLQ A;  3Q0N A;  4I37 A;  2Q5D A;  4HNM A;  3TX7 A;  2IX3 A;  3Q0O A;  3OQS A;  2X1G F;  4R0Z A;  2H4M A;  3K4E A;  5SW9 A;  2JKR B;  2WTK A;  4Y5J A;  5CL3 A;  4DZS A;  3EA5 B;  3L6X A;  4D4E A;  3L6Y A;  3Q5U A;  3GVO A;  1B3U A;  1JDH A;  4UQI B;  1XQS A;  4EV8 A;  4JW3 C;  3TPO A;  2X19 B;  3QGB A;  5CLB A;  3ZIK A;  2Z5N A;  3UL0 B;  1M8Z A;  5HUW C;  4OO6 A;  4CB8 A;  3ZIQ A;  5EKG A;  4D49 A;  3ZIN A;  4K92 A;  3BX3 A;  4V3R A;  4B18 A;  4FQ3 A;  4CBA A;  3VWA A;  2RU4 B;  4CV5 B;  3UKW B;  3TT9 A;  2Z6G A;  2JAK A;  1W63 A;  2BAP A;  5CLA A;  4U5L A;  5KL1 A;  4IMJ A;  4WV6 A;  1IAL A;  2NPP B;  2Z6H A;  5KUB A;  2Z5O A;  4GMN A;  2VGL A;  3O4X A;  5CLE A;  4UAE A;  3K49 A;  4BA3 A;  3BSX A;  3C2H A;  1PJM B;  4MZ5 E;  4DBA A;  2PKG A;  2GL7 A;  3NMW A;  3GS3 A;  3LTM A;  3O2S A;  3LWW A;  3QG9 A;  4JW2 A;  4EVT A;  3EBB A;  3BX2 A;  1IBR B;  4FZA A;  3LTJ A;  3JY1 A;  1JPP A;  3Q0L A;  1GCJ A;  3OBV A;  3GAE A;  2NYL A;  4FFB C;  4G3A A;  3QGC A;  4U2X D;  3BWT A;  4BQK A;  3WYF C;  3FGA A;  3TJZ B;  1M1E A;  4I6I A;  1QGR A;  1JPW A;  1BK5 A;  4R11 A;  2QK2 A;  4DB9 A;  3BSB A;  3NMZ A;  2BKU B;  3GQ2 A;  2QK1 A;  1UN0 A;  4QMJ A;  5H2W A;  4DJS A;  3ZKV A;  3GVT A;  4I8M A;  4PLR A;  5BZ1 A;  2BNX A;  3WPT A;  3WOZ A;  2Z5K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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