4U58A

Importin-alpha minor nls site inhibitor
Total Genus 173
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
426
structure length
426
Chain Sequence
GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Importin subunit alpha-1
publication title Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
pubmed doi rcsb
source organism Mus musculus
molecule tags Transport protein
total genus 173
structure length 426
sequence length 426
ec nomenclature
pdb deposition date 2014-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00514 Arm Armadillo/beta-catenin-like repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat Variant 4u58A00
4CT7B 3T7UA 3GVTA 1HO8A 3PSTA 2JKTA 4FFBC 4U5LA 4E4VA 3UKXB 2NYMA 3H3DX 5J3VA 3BX2A 4MZ5E 1O6OA 4NEEA 3ZIQA 1UPLA 4QMIA 1I7WA 4FDDA 3QG9A 4H3KA 1QGKA 1EE5A 4R0ZA 3K5YA 5DN7A 3UKYB 3ODSA 3C5WA 2YJYA 3GRLA 3WYFC 3Q0LA 1IBRB 4V3QA 5SW9A 3TX7A 1IQ1C 5SVZA 4CV5B 2JKRA 4IMJA 3GS3A 4DB6A 4FQ3A 5EWPA 5BZ1A 3BSBA 4EVTA 4YJLA 2IE3A 2GL7A 2QNAA 3K7VA 3BX3A 4I5NA 1Q1SC 4BQKA 3FGAB 1W63B 2BCTA 4RXHB 2YNRA 3Q0OA 2XA7B 4Y5JA 5HUYC 3OBVA 1Q1TC 2F31A 4HXTA 4B8PA 3KNDA 3NMWA 4I5LA 2NYLB 4O27A 2BNXA 3L6YA 1O6PA 4BA3A 2QK1A 1XQRA 3QMLC 1PJNB 2Z5MA 3Q0NA 3UVUA 2OF3A 2IAEA 3GVOA 2Z6GA 5CTTA 1T08A 2W3CA 4A0CA 1IB2A 3Q0RA 1M8WA 2WTKA 1XQSA 3K5QA 2VGLA 4DVGB 4U5SA 3OPBA 3OUXA 4U5OA 2IE4A 3TJZB 3ODRA 2Z5JA 4U5VA 4UWXA 3LTJA 3OUWA 1WA5B 3O4XA 4YI0C 3K61A 3W3UA 1GCJA 3Q5UA 4DJSA 4YGXA 3ZIRA 1EJLI 5B56A 3FEYC 3ND2A 4R11A 4YJEA 4U5UA 4CT6B 2Z5OA 3NOWA 3TT9A 5LSWA 1M5NS 2BKUB 3UKWB 3ZIPA 5D5KC 1UN0A 3EBBA 4KZGA 1M8YA 1OYZA 1QGRA 1B3UA 3IBVA 4OIHA 3BCTA 3QGBA 3ZHPA 3UKZB 5JJAA 3BWTA 3TPOA 4YK6A 3VWAA 4BPLA 3ZIOA 2X1GF 4MFVA 4U58A 1JPPA 3FEXC 4L7MA 3O2SA 3K5ZA 1IALA 2JDQA 2IX3A 3PSPA 5EKGA 1BK5A 3NMXA 4PLSA 4P6ZB 3Q0PA 4TNMA 1UKLA 3GQ2A 4UQIB 2P8QA 2NPPA 4NZWA 2OT8A 3QHEA 1TH1A 2JKTB 2NYMB 3C2GA 1M8XA 1I7XA 1XM9A 1G3JA 3TPMA 1JDHA 4HM9A 4B18A 3BSXA 5AEIA 2RU4A 4V3RA 1M1EA 4XZRB 3V74A 2BAPA 4EV8A 4DB9A 2DB0A 2IW3A 3RZXA 4CBAA 3K64A 4CB9A 1M8ZA 5KLAA 4IMIA 5HUWC 3BTRC 2Z6HA 2JKRB 1V18A 3EA5B 3AU3A 5EKFA 3K62A 2C1MA 4ZDUA 3K7WA 4H3HA 2C1TA 5H2WA 4FZDA 3A6PA 4U5NA 4V3OA 1Y2AC 3L6XA 1U6GC 3LWWA 3ZKVA 4UAFB 3Q0SA 4G3AA 1JPWA 4U3JC 4FZFA 2Z5KA 3FGAA 3DW8A 4CRVB 4PVZA 1W63A 5K6SA 4HTVA 3V6YA 4RZPA 1LUJA 2XA7A 3GB8A 4EVAA 3V71A 2RU4B 2YNSA 4DZSA 2NYLA 2IAEB 5FC8E 5BZ5A 5KLRB 3WOZA 4RV1A 1PJMB 1EE4A 1EJYI 4D4EA 2FV2A 2VGLB 4DB8A 3EG5B 5BZVA 4I2ZA 3K4EA 5SWFA 4D49A 4UADA 4PLQA 4QMHA 3IFQA 2Z5NA 3OQSA 4CRUB 3VE6A 4DBAA 1W9CA 3WPTA 2QMRA 5BYMA 5H2XA 4EV9A 1LRVA 4JW2B 1Z2CB 4GMOA 4MZ6E 3O2TA 4QMJA 1F59A 4GMNA 5K9SA 3RZ9A 4CB8A 4MFUA 3WOYA 3O2QA 4PLRA 4UAEA 4LACA 4U54A 2PF4A 5HHGE 3QGCA 5KL8A 2JAKA 4K6JA 3NMZA 5KLTB 4ADYA 4R10A 3K49A 4WV6A 2H4MA 3L3FX 1UPKA 3TJ3A 4OO6A 4K92A 4B8JA 5BZUA 3C2HA 4JLQA 5KL1A 4P6ZG 3GNIA 2Q5DA 1QBKB 2IWHA 4FZAA 3ZINA 1BK6A 3Q0QA 2X19B 4EVPA 3L3QA 1QZ7A 5E6QB 4I2WA 3UL1B 2NPPB 1WA5C 3GAEA 4HNMA 2QK2A 2PKGA 3Q0MA 4B8OA 3DADA 3LTMA 3UL0B 4UQIA
chains in the Genus database with same CATH superfamily
4CT7B 3T7UA 4I0YA 3GVTA 5CL5A 1HO8A 3PSTA 2JKTA 4FFBC 4U5LA 4E4VA 3UKXB 2NYMA 3H3DX 5J3VA 3BX2A 4MZ5E 1O6OA 4NEEA 3ZIQA 1UPLA 4QMIA 1I7WA 4FDDA 1LSHA 3QG9A 4H3KA 1QGKA 1EE5A 4R0ZA 3K5YA 5CLCA 5DN7A 3UKYB 3ODSA 3C5WA 2YJYA 3GRLA 3WYFC 3Q0LA 1IBRB 4V3QA 5SW9A 3TX7A 5CL6A 1IQ1C 5SVZA 4CV5B 2JKRA 3VLDA 4IMJA 5CL9A 3GS3A 4DB6A 4FQ3A 5EWPA 5BZ1A 3BSBA 4A3TA 4EVTA 4YJLA 2IE3A 2GL7A 2QNAA 3K7VA 4JKQA 4I5NA 3BX3A 1Q1SC 4BQKA 3FGAB 1W63B 2BCTA 4I6IA 4RXHB 2YNRA 3Q0OA 2XA7B 4Y5JA 5HUYC 3OBVA 1Q1TC 2F31A 4HXTA 4B8PA 3KNDA 3NMWA 4I5LA 3JY1A 2NYLB 4O27A 2BNXA 3L6YA 3T8SA 1O6PA 4BA3A 2QK1A 1XQRA 3QMLC 1PJNB 2Z5MA 3Q0NA 3UVUA 2OF3A 5CLEA 2IAEA 3GVOA 2XOAA 2Z6GA 5CTTA 1T08A 2W3CA 3SL9A 4A0CA 1IB2A 3Q0RA 1M8WA 2WTKA 1XQSA 3K5QA 2VGLA 4DVGB 4U5SA 3OPBA 3OUXA 4U5OA 2IE4A 3TJZB 3ODRA 2Z5JA 4U5VA 4UWXA 3LTJA 3OUWA 1WA5B 3O4XA 4YI0C 3K61A 3W3UA 1GCJA 3Q5UA 4DJSA 4YGXA 4I7IA 3ZIRA 1EJLI 5B56A 3FEYC 5KUBA 3ND2A 4JW2A 4R11A 4U2XD 4YJEA 4U5UA 4CT6B 2Z5OA 3NOWA 3TT9A 5LSWA 1M5NS 3UJ0A 2BKUB 3UKWB 3ZIPA 5D5KC 1UN0A 3EBBA 4KZGA 1M8YA 1OYZA 1QGRA 1B3UA 3IBVA 4OIHA 3BCTA 3QGBA 3ZHPA 3UKZB 5JJAA 3BWTA 3TPOA 4YK6A 3VWAA 4BPLA 3ZIOA 2X1GF 4MFVA 4U58A 5CL4A 1JPPA 3FEXC 4L7MA 3O2SA 3K5ZA 1IALA 2JDQA 2IX3A 3PSPA 5EKGA 1BK5A 3NMXA 4PLSA 4P6ZB 3Q0PA 4TNMA 1UKLA 3GQ2A 4UQIB 2P8QA 2NPPA 1TE4A 4NZWA 2OT8A 3JXZA 3QHEA 1TH1A 2JKTB 3BVSA 2NYMB 3C2GA 1M8XA 1I7XA 1XM9A 4FP7A 1G3JA 3TPMA 1JDHA 4HM9A 4B18A 3BSXA 5AEIA 2RU4A 1N4KA 1M1EA 4V3RA 4XZRB 3V74A 2BAPA 4EV8A 3JXYA 4DB9A 2DB0A 2IW3A 3RZXA 4CBAA 3K64A 4CB9A 1M8ZA 5KLAA 4IMIA 5HUWC 3BTRC 2Z6HA 4I1EA 2JKRB 1V18A 5CL7A 3EA5B 3AU3A 5EKFA 3K62A 2C1MA 4ZDUA 3K7WA 3VLEA 3ZILA 4H3HA 2C1TA 5H2WA 4FZDA 3A6PA 4U5NA 3VLFA 4V3OA 1Y2AC 4I96A 3L6XA 5CLAA 1U6GC 3LWWA 3ZKVA 4UAFB 3Q0SA 4G3AA 1JPWA 5CLDA 4U3JC 4A3VA 4FZFA 2Z5KA 3FGAA 3DW8A 4CRVB 4PVZA 1W63A 5K6SA 4HTVA 3V6YA 4RZPA 1LUJA 2XA7A 3GB8A 4EVAA 3V71A 2RU4B 2YNSA 4DZSA 2NYLA 2IAEB 5FC8E 5BZ5A 3SLAA 5KLRB 3WOZA 4I37A 4RV1A 5CL8A 1PJMB 1EE4A 1EJYI 4D4EA 2FV2A 2VGLB 4DB8A 3EG5B 5BZVA 4I2ZA 3K4EA 5SWFA 4D49A 4UADA 3JX7A 4PLQA 4QMHA 3IFQA 2Z5NA 3OQSA 4CRUB 3VE6A 4DBAA 1W9CA 3WPTA 2QMRA 5BYMA 5H2XA 4I3NA 4EV9A 1LRVA 4JW2B 1Z2CB 4GMOA 5CLBA 4MZ6E 3O2TA 4QMJA 1F59A 4GMNA 5K9SA 4I2SA 3RZ9A 4CB8A 4MFUA 3WOYA 3O2QA 4PLRA 4UAEA 4LACA 4U54A 2PF4A 5HHGE 3QGCA 5KL8A 2JAKA 4L4HA 4K6JA 3NMZA 5KLTB 4ADYA 4R10A 3K49A 4WV6A 2H4MA 3L3FX 1UPKA 3TJ3A 4L4IA 4OO6A 4K92A 4B8JA 3UJ4A 5BZUA 3C2HA 4JLQA 5KL1A 4I8MA 4P6ZG 3GNIA 5CL3A 2Q5DA 1QBKB 2IWHA 4FZAA 3ZINA 1BK6A 3Q0QA 2X19B 4EVPA 3L3QA 1QZ7A 4JW3C 5E6QB 4I2WA 3ZIKA 3UL1B 2NPPB 1WA5C 3GAEA 4HNMA 2QK2A 2PKGA 3Q0MA 4B8OA 3DADA 3LTMA 3UL0B 4UQIA
chains in the Genus database with same CATH topology
4CT7B 3T7UA 4I0YA 3GVTA 5CL5A 1HO8A 3PSTA 2JKTA 4FFBC 4U5LA 4E4VA 3UKXB 2NYMA 3H3DX 5J3VA 3BX2A 4MZ5E 1O6OA 4NEEA 3ZIQA 1UPLA 4QMIA 1I7WA 4FDDA 3QG9A 4H3KA 1QGKA 1EE5A 4R0ZA 3K5YA 5CLCA 5DN7A 3UKYB 3ODSA 3C5WA 2YJYA 3GRLA 3WYFC 3Q0LA 1IBRB 4V3QA 5SW9A 3TX7A 5CL6A 1IQ1C 5SVZA 4CV5B 2JKRA 3VLDA 4IMJA 5CL9A 3GS3A 4DB6A 4FQ3A 5EWPA 5BZ1A 3BSBA 4A3TA 4EVTA 4YJLA 2IE3A 2GL7A 2QNAA 3K7VA 4JKQA 4I5NA 3BX3A 1Q1SC 4BQKA 3FGAB 1W63B 2BCTA 4I6IA 4RXHB 2YNRA 3Q0OA 2XA7B 4Y5JA 5HUYC 3OBVA 1Q1TC 2F31A 4HXTA 4B8PA 3KNDA 3NMWA 4I5LA 3JY1A 2NYLB 4O27A 2BNXA 3L6YA 1O6PA 4BA3A 2QK1A 1XQRA 3QMLC 1PJNB 2Z5MA 3Q0NA 3UVUA 2OF3A 5CLEA 2IAEA 3GVOA 2XOAA 2Z6GA 5CTTA 1T08A 2W3CA 3SL9A 4A0CA 1IB2A 3Q0RA 1M8WA 2WTKA 1XQSA 3K5QA 2VGLA 4DVGB 4U5SA 3OPBA 3OUXA 4U5OA 2IE4A 3TJZB 3ODRA 2Z5JA 4U5VA 4UWXA 3LTJA 3OUWA 1WA5B 3O4XA 4YI0C 3K61A 3W3UA 1GCJA 3Q5UA 4DJSA 4YGXA 4I7IA 3ZIRA 1EJLI 5B56A 3FEYC 5KUBA 3ND2A 4JW2A 4R11A 4U2XD 4YJEA 4U5UA 4CT6B 2Z5OA 3NOWA 3TT9A 5LSWA 1M5NS 2BKUB 3UKWB 3ZIPA 5D5KC 1UN0A 3EBBA 4KZGA 1M8YA 1OYZA 1QGRA 1B3UA 3IBVA 4OIHA 3BCTA 3QGBA 3ZHPA 3UKZB 5JJAA 3BWTA 3TPOA 4YK6A 3VWAA 4BPLA 3ZIOA 2X1GF 4MFVA 4U58A 5CL4A 1JPPA 3FEXC 4L7MA 3O2SA 3K5ZA 1IALA 2JDQA 2IX3A 3PSPA 5EKGA 1BK5A 3NMXA 4PLSA 4P6ZB 3Q0PA 4TNMA 1UKLA 3GQ2A 4UQIB 2P8QA 2NPPA 1TE4A 4NZWA 2OT8A 3JXZA 3QHEA 1TH1A 2JKTB 3BVSA 2NYMB 3C2GA 1M8XA 1I7XA 1XM9A 4FP7A 1G3JA 3TPMA 1JDHA 4HM9A 4B18A 3BSXA 5AEIA 2RU4A 4V3RA 1M1EA 4XZRB 3V74A 2BAPA 4EV8A 3JXYA 4DB9A 2DB0A 2IW3A 3RZXA 4CBAA 3K64A 4CB9A 1M8ZA 5KLAA 4IMIA 5HUWC 3BTRC 2Z6HA 4I1EA 2JKRB 1V18A 5CL7A 3EA5B 3AU3A 5EKFA 3K62A 2C1MA 4ZDUA 3K7WA 3VLEA 3ZILA 4H3HA 2C1TA 5H2WA 4FZDA 3A6PA 4U5NA 3VLFA 4V3OA 1Y2AC 4I96A 3L6XA 5CLAA 1U6GC 3LWWA 3ZKVA 4UAFB 3Q0SA 4G3AA 1JPWA 5CLDA 4U3JC 4A3VA 4FZFA 2Z5KA 3FGAA 3DW8A 4CRVB 4PVZA 1W63A 5K6SA 4HTVA 3V6YA 4RZPA 1LUJA 2XA7A 3GB8A 4EVAA 3V71A 2RU4B 2YNSA 4DZSA 2NYLA 2IAEB 5FC8E 5BZ5A 3SLAA 5KLRB 3WOZA 4I37A 4RV1A 5CL8A 1PJMB 1EE4A 1EJYI 4D4EA 2FV2A 2VGLB 4DB8A 3EG5B 5BZVA 4I2ZA 3K4EA 5SWFA 4D49A 4UADA 3JX7A 4PLQA 4QMHA 3IFQA 2Z5NA 3OQSA 4CRUB 3VE6A 4DBAA 1W9CA 3WPTA 2QMRA 5BYMA 5H2XA 4I3NA 4EV9A 1LRVA 4JW2B 1Z2CB 4GMOA 5CLBA 4MZ6E 3O2TA 4QMJA 1F59A 4GMNA 5K9SA 4I2SA 3RZ9A 4CB8A 4MFUA 3WOYA 3O2QA 4PLRA 4UAEA 4LACA 4U54A 2PF4A 5HHGE 3QGCA 5KL8A 2JAKA 4L4HA 4K6JA 3NMZA 5KLTB 4ADYA 4R10A 3K49A 4WV6A 2H4MA 3L3FX 1UPKA 3TJ3A 4L4IA 4OO6A 4K92A 4B8JA 5BZUA 3C2HA 4JLQA 5KL1A 4I8MA 4P6ZG 3GNIA 5CL3A 2Q5DA 1QBKB 2IWHA 4FZAA 3ZINA 1BK6A 3Q0QA 2X19B 4EVPA 3L3QA 1QZ7A 4JW3C 5E6QB 4I2WA 3ZIKA 3UL1B 2NPPB 1WA5C 3GAEA 4HNMA 2QK2A 2PKGA 3Q0MA 4B8OA 3DADA 3LTMA 3UL0B 4UQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CT7 B;  3T7U A;  3GVT A;  1HO8 A;  3PST A;  2JKT A;  4FFB C;  4U5L A;  4E4V A;  3UKX B;  2NYM A;  3H3D X;  5J3V A;  3BX2 A;  4MZ5 E;  1O6O A;  4NEE A;  3ZIQ A;  1UPL A;  4QMI A;  1I7W A;  4FDD A;  3QG9 A;  4H3K A;  1QGK A;  1EE5 A;  4R0Z A;  3K5Y A;  5DN7 A;  3UKY B;  3ODS A;  3C5W A;  2YJY A;  3GRL A;  3WYF C;  3Q0L A;  1IBR B;  4V3Q A;  5SW9 A;  3TX7 A;  1IQ1 C;  5SVZ A;  4CV5 B;  2JKR A;  4IMJ A;  3GS3 A;  4DB6 A;  4FQ3 A;  5EWP A;  5BZ1 A;  3BSB A;  4EVT A;  4YJL A;  2IE3 A;  2GL7 A;  2QNA A;  3K7V A;  3BX3 A;  4I5N A;  1Q1S C;  4BQK A;  3FGA B;  1W63 B;  2BCT A;  4RXH B;  2YNR A;  3Q0O A;  2XA7 B;  4Y5J A;  5HUY C;  3OBV A;  1Q1T C;  2F31 A;  4HXT A;  4B8P A;  3KND A;  3NMW A;  4I5L A;  2NYL B;  4O27 A;  2BNX A;  3L6Y A;  1O6P A;  4BA3 A;  2QK1 A;  1XQR A;  3QML C;  1PJN B;  2Z5M A;  3Q0N A;  3UVU A;  2OF3 A;  2IAE A;  3GVO A;  2Z6G A;  5CTT A;  1T08 A;  2W3C A;  4A0C A;  1IB2 A;  3Q0R A;  1M8W A;  2WTK A;  1XQS A;  3K5Q A;  2VGL A;  4DVG B;  4U5S A;  3OPB A;  3OUX A;  4U5O A;  2IE4 A;  3TJZ B;  3ODR A;  2Z5J A;  4U5V A;  4UWX A;  3LTJ A;  3OUW A;  1WA5 B;  3O4X A;  4YI0 C;  3K61 A;  3W3U A;  1GCJ A;  3Q5U A;  4DJS A;  4YGX A;  3ZIR A;  1EJL I;  5B56 A;  3FEY C;  3ND2 A;  4R11 A;  4YJE A;  4U5U A;  4CT6 B;  2Z5O A;  3NOW A;  3TT9 A;  5LSW A;  1M5N S;  2BKU B;  3UKW B;  3ZIP A;  5D5K C;  1UN0 A;  3EBB A;  4KZG A;  1M8Y A;  1OYZ A;  1QGR A;  1B3U A;  3IBV A;  4OIH A;  3BCT A;  3QGB A;  3ZHP A;  3UKZ B;  5JJA A;  3BWT A;  3TPO A;  4YK6 A;  3VWA A;  4BPL A;  3ZIO A;  2X1G F;  4MFV A;  4U58 A;  1JPP A;  3FEX C;  4L7M A;  3O2S A;  3K5Z A;  1IAL A;  2JDQ A;  2IX3 A;  3PSP A;  5EKG A;  1BK5 A;  3NMX A;  4PLS A;  4P6Z B;  3Q0P A;  4TNM A;  1UKL A;  3GQ2 A;  4UQI B;  2P8Q A;  2NPP A;  4NZW A;  2OT8 A;  3QHE A;  1TH1 A;  2JKT B;  2NYM B;  3C2G A;  1M8X A;  1I7X A;  1XM9 A;  1G3J A;  3TPM A;  1JDH A;  4HM9 A;  4B18 A;  3BSX A;  5AEI A;  2RU4 A;  4V3R A;  1M1E A;  4XZR B;  3V74 A;  2BAP A;  4EV8 A;  4DB9 A;  2DB0 A;  2IW3 A;  3RZX A;  4CBA A;  3K64 A;  4CB9 A;  1M8Z A;  5KLA A;  4IMI A;  5HUW C;  3BTR C;  2Z6H A;  2JKR B;  1V18 A;  3EA5 B;  3AU3 A;  5EKF A;  3K62 A;  2C1M A;  4ZDU A;  3K7W A;  4H3H A;  2C1T A;  5H2W A;  4FZD A;  3A6P A;  4U5N A;  4V3O A;  1Y2A C;  3L6X A;  1U6G C;  3LWW A;  3ZKV A;  4UAF B;  3Q0S A;  4G3A A;  1JPW A;  4U3J C;  4FZF A;  2Z5K A;  3FGA A;  3DW8 A;  4CRV B;  4PVZ A;  1W63 A;  5K6S A;  4HTV A;  3V6Y A;  4RZP A;  1LUJ A;  2XA7 A;  3GB8 A;  4EVA A;  3V71 A;  2RU4 B;  2YNS A;  4DZS A;  2NYL A;  2IAE B;  5FC8 E;  5BZ5 A;  5KLR B;  3WOZ A;  4RV1 A;  1PJM B;  1EE4 A;  1EJY I;  4D4E A;  2FV2 A;  2VGL B;  4DB8 A;  3EG5 B;  5BZV A;  4I2Z A;  3K4E A;  5SWF A;  4D49 A;  4UAD A;  4PLQ A;  4QMH A;  3IFQ A;  2Z5N A;  3OQS A;  4CRU B;  3VE6 A;  4DBA A;  1W9C A;  3WPT A;  2QMR A;  5BYM A;  5H2X A;  4EV9 A;  1LRV A;  4JW2 B;  1Z2C B;  4GMO A;  4MZ6 E;  3O2T A;  4QMJ A;  1F59 A;  4GMN A;  5K9S A;  3RZ9 A;  4CB8 A;  4MFU A;  3WOY A;  3O2Q A;  4PLR A;  4UAE A;  4LAC A;  4U54 A;  2PF4 A;  5HHG E;  3QGC A;  5KL8 A;  2JAK A;  4K6J A;  3NMZ A;  5KLT B;  4ADY A;  4R10 A;  3K49 A;  4WV6 A;  2H4M A;  3L3F X;  1UPK A;  3TJ3 A;  4OO6 A;  4K92 A;  4B8J A;  5BZU A;  3C2H A;  4JLQ A;  5KL1 A;  4P6Z G;  3GNI A;  2Q5D A;  1QBK B;  2IWH A;  4FZA A;  3ZIN A;  1BK6 A;  3Q0Q A;  2X19 B;  4EVP A;  3L3Q A;  1QZ7 A;  5E6Q B;  4I2W A;  3UL1 B;  2NPP B;  1WA5 C;  3GAE A;  4HNM A;  2QK2 A;  2PKG A;  3Q0M A;  4B8O A;  3DAD A;  3LTM A;  3UL0 B;  4UQI A; 
#chains in the Genus database with same CATH topology
 4CT7 B;  3T7U A;  4I0Y A;  3GVT A;  5CL5 A;  1HO8 A;  3PST A;  2JKT A;  4FFB C;  4U5L A;  4E4V A;  3UKX B;  2NYM A;  3H3D X;  5J3V A;  3BX2 A;  4MZ5 E;  1O6O A;  4NEE A;  3ZIQ A;  1UPL A;  4QMI A;  1I7W A;  4FDD A;  1LSH A;  3QG9 A;  4H3K A;  1QGK A;  1EE5 A;  4R0Z A;  3K5Y A;  5CLC A;  5DN7 A;  3UKY B;  3ODS A;  3C5W A;  2YJY A;  3GRL A;  3WYF C;  3Q0L A;  1IBR B;  4V3Q A;  5SW9 A;  3TX7 A;  5CL6 A;  1IQ1 C;  5SVZ A;  4CV5 B;  2JKR A;  3VLD A;  4IMJ A;  5CL9 A;  3GS3 A;  4DB6 A;  4FQ3 A;  5EWP A;  5BZ1 A;  3BSB A;  4A3T A;  4EVT A;  4YJL A;  2IE3 A;  2GL7 A;  2QNA A;  3K7V A;  4JKQ A;  4I5N A;  3BX3 A;  1Q1S C;  4BQK A;  3FGA B;  1W63 B;  2BCT A;  4I6I A;  4RXH B;  2YNR A;  3Q0O A;  2XA7 B;  4Y5J A;  5HUY C;  3OBV A;  1Q1T C;  2F31 A;  4HXT A;  4B8P A;  3KND A;  3NMW A;  4I5L A;  3JY1 A;  2NYL B;  4O27 A;  2BNX A;  3L6Y A;  3T8S A;  1O6P A;  4BA3 A;  2QK1 A;  1XQR A;  3QML C;  1PJN B;  2Z5M A;  3Q0N A;  3UVU A;  2OF3 A;  5CLE A;  2IAE A;  3GVO A;  2XOA A;  2Z6G A;  5CTT A;  1T08 A;  2W3C A;  3SL9 A;  4A0C A;  1IB2 A;  3Q0R A;  1M8W A;  2WTK A;  1XQS A;  3K5Q A;  2VGL A;  4DVG B;  4U5S A;  3OPB A;  3OUX A;  4U5O A;  2IE4 A;  3TJZ B;  3ODR A;  2Z5J A;  4U5V A;  4UWX A;  3LTJ A;  3OUW A;  1WA5 B;  3O4X A;  4YI0 C;  3K61 A;  3W3U A;  1GCJ A;  3Q5U A;  4DJS A;  4YGX A;  4I7I A;  3ZIR A;  1EJL I;  5B56 A;  3FEY C;  5KUB A;  3ND2 A;  4JW2 A;  4R11 A;  4U2X D;  4YJE A;  4U5U A;  4CT6 B;  2Z5O A;  3NOW A;  3TT9 A;  5LSW A;  1M5N S;  3UJ0 A;  2BKU B;  3UKW B;  3ZIP A;  5D5K C;  1UN0 A;  3EBB A;  4KZG A;  1M8Y A;  1OYZ A;  1QGR A;  1B3U A;  3IBV A;  4OIH A;  3BCT A;  3QGB A;  3ZHP A;  3UKZ B;  5JJA A;  3BWT A;  3TPO A;  4YK6 A;  3VWA A;  4BPL A;  3ZIO A;  2X1G F;  4MFV A;  4U58 A;  5CL4 A;  1JPP A;  3FEX C;  4L7M A;  3O2S A;  3K5Z A;  1IAL A;  2JDQ A;  2IX3 A;  3PSP A;  5EKG A;  1BK5 A;  3NMX A;  4PLS A;  4P6Z B;  3Q0P A;  4TNM A;  1UKL A;  3GQ2 A;  4UQI B;  2P8Q A;  2NPP A;  1TE4 A;  4NZW A;  2OT8 A;  3JXZ A;  3QHE A;  1TH1 A;  2JKT B;  3BVS A;  2NYM B;  3C2G A;  1M8X A;  1I7X A;  1XM9 A;  4FP7 A;  1G3J A;  3TPM A;  1JDH A;  4HM9 A;  4B18 A;  3BSX A;  5AEI A;  2RU4 A;  1N4K A;  1M1E A;  4V3R A;  4XZR B;  3V74 A;  2BAP A;  4EV8 A;  3JXY A;  4DB9 A;  2DB0 A;  2IW3 A;  3RZX A;  4CBA A;  3K64 A;  4CB9 A;  1M8Z A;  5KLA A;  4IMI A;  5HUW C;  3BTR C;  2Z6H A;  4I1E A;  2JKR B;  1V18 A;  5CL7 A;  3EA5 B;  3AU3 A;  5EKF A;  3K62 A;  2C1M A;  4ZDU A;  3K7W A;  3VLE A;  3ZIL A;  4H3H A;  2C1T A;  5H2W A;  4FZD A;  3A6P A;  4U5N A;  3VLF A;  4V3O A;  1Y2A C;  4I96 A;  3L6X A;  5CLA A;  1U6G C;  3LWW A;  3ZKV A;  4UAF B;  3Q0S A;  4G3A A;  1JPW A;  5CLD A;  4U3J C;  4A3V A;  4FZF A;  2Z5K A;  3FGA A;  3DW8 A;  4CRV B;  4PVZ A;  1W63 A;  5K6S A;  4HTV A;  3V6Y A;  4RZP A;  1LUJ A;  2XA7 A;  3GB8 A;  4EVA A;  3V71 A;  2RU4 B;  2YNS A;  4DZS A;  2NYL A;  2IAE B;  5FC8 E;  5BZ5 A;  3SLA A;  5KLR B;  3WOZ A;  4I37 A;  4RV1 A;  5CL8 A;  1PJM B;  1EE4 A;  1EJY I;  4D4E A;  2FV2 A;  2VGL B;  4DB8 A;  3EG5 B;  5BZV A;  4I2Z A;  3K4E A;  5SWF A;  4D49 A;  4UAD A;  3JX7 A;  4PLQ A;  4QMH A;  3IFQ A;  2Z5N A;  3OQS A;  4CRU B;  3VE6 A;  4DBA A;  1W9C A;  3WPT A;  2QMR A;  5BYM A;  5H2X A;  4I3N A;  4EV9 A;  1LRV A;  4JW2 B;  1Z2C B;  4GMO A;  5CLB A;  4MZ6 E;  3O2T A;  4QMJ A;  1F59 A;  4GMN A;  5K9S A;  4I2S A;  3RZ9 A;  4CB8 A;  4MFU A;  3WOY A;  3O2Q A;  4PLR A;  4UAE A;  4LAC A;  4U54 A;  2PF4 A;  5HHG E;  3QGC A;  5KL8 A;  2JAK A;  4L4H A;  4K6J A;  3NMZ A;  5KLT B;  4ADY A;  4R10 A;  3K49 A;  4WV6 A;  2H4M A;  3L3F X;  1UPK A;  3TJ3 A;  4L4I A;  4OO6 A;  4K92 A;  4B8J A;  3UJ4 A;  5BZU A;  3C2H A;  4JLQ A;  5KL1 A;  4I8M A;  4P6Z G;  3GNI A;  5CL3 A;  2Q5D A;  1QBK B;  2IWH A;  4FZA A;  3ZIN A;  1BK6 A;  3Q0Q A;  2X19 B;  4EVP A;  3L3Q A;  1QZ7 A;  4JW3 C;  5E6Q B;  4I2W A;  3ZIK A;  3UL1 B;  2NPP B;  1WA5 C;  3GAE A;  4HNM A;  2QK2 A;  2PKG A;  3Q0M A;  4B8O A;  3DAD A;  3LTM A;  3UL0 B;  4UQI A; 
#chains in the Genus database with same CATH homology
 4CT7 B;  3T7U A;  4I0Y A;  3GVT A;  5CL5 A;  1HO8 A;  3PST A;  2JKT A;  4FFB C;  4U5L A;  4E4V A;  3UKX B;  2NYM A;  3H3D X;  5J3V A;  3BX2 A;  4MZ5 E;  1O6O A;  4NEE A;  3ZIQ A;  1UPL A;  4QMI A;  1I7W A;  4FDD A;  3QG9 A;  4H3K A;  1QGK A;  1EE5 A;  4R0Z A;  3K5Y A;  5CLC A;  5DN7 A;  3UKY B;  3ODS A;  3C5W A;  2YJY A;  3GRL A;  3WYF C;  3Q0L A;  1IBR B;  4V3Q A;  5SW9 A;  3TX7 A;  5CL6 A;  1IQ1 C;  5SVZ A;  4CV5 B;  2JKR A;  3VLD A;  4IMJ A;  5CL9 A;  3GS3 A;  4DB6 A;  4FQ3 A;  5EWP A;  5BZ1 A;  3BSB A;  4A3T A;  4EVT A;  4YJL A;  2IE3 A;  2GL7 A;  2QNA A;  3K7V A;  4JKQ A;  4I5N A;  3BX3 A;  1Q1S C;  4BQK A;  3FGA B;  1W63 B;  2BCT A;  4I6I A;  4RXH B;  2YNR A;  3Q0O A;  2XA7 B;  4Y5J A;  5HUY C;  3OBV A;  1Q1T C;  2F31 A;  4HXT A;  4B8P A;  3KND A;  3NMW A;  4I5L A;  3JY1 A;  2NYL B;  4O27 A;  2BNX A;  3L6Y A;  1O6P A;  4BA3 A;  2QK1 A;  1XQR A;  3QML C;  1PJN B;  2Z5M A;  3Q0N A;  3UVU A;  2OF3 A;  5CLE A;  2IAE A;  3GVO A;  2XOA A;  2Z6G A;  5CTT A;  1T08 A;  2W3C A;  3SL9 A;  4A0C A;  1IB2 A;  3Q0R A;  1M8W A;  2WTK A;  1XQS A;  3K5Q A;  2VGL A;  4DVG B;  4U5S A;  3OPB A;  3OUX A;  4U5O A;  2IE4 A;  3TJZ B;  3ODR A;  2Z5J A;  4U5V A;  4UWX A;  3LTJ A;  3OUW A;  1WA5 B;  3O4X A;  4YI0 C;  3K61 A;  3W3U A;  1GCJ A;  3Q5U A;  4DJS A;  4YGX A;  4I7I A;  3ZIR A;  1EJL I;  5B56 A;  3FEY C;  5KUB A;  3ND2 A;  4JW2 A;  4R11 A;  4U2X D;  4YJE A;  4U5U A;  4CT6 B;  2Z5O A;  3NOW A;  3TT9 A;  5LSW A;  1M5N S;  2BKU B;  3UKW B;  3ZIP A;  5D5K C;  1UN0 A;  3EBB A;  4KZG A;  1M8Y A;  1OYZ A;  1QGR A;  1B3U A;  3IBV A;  4OIH A;  3BCT A;  3QGB A;  3ZHP A;  3UKZ B;  5JJA A;  3BWT A;  3TPO A;  4YK6 A;  3VWA A;  4BPL A;  3ZIO A;  2X1G F;  4MFV A;  4U58 A;  5CL4 A;  1JPP A;  3FEX C;  4L7M A;  3O2S A;  3K5Z A;  1IAL A;  2JDQ A;  2IX3 A;  3PSP A;  5EKG A;  1BK5 A;  3NMX A;  4PLS A;  4P6Z B;  3Q0P A;  4TNM A;  1UKL A;  3GQ2 A;  4UQI B;  2P8Q A;  2NPP A;  1TE4 A;  4NZW A;  2OT8 A;  3JXZ A;  3QHE A;  1TH1 A;  2JKT B;  3BVS A;  2NYM B;  3C2G A;  1M8X A;  1I7X A;  1XM9 A;  4FP7 A;  1G3J A;  3TPM A;  1JDH A;  4HM9 A;  4B18 A;  3BSX A;  5AEI A;  2RU4 A;  4V3R A;  1M1E A;  4XZR B;  3V74 A;  2BAP A;  4EV8 A;  3JXY A;  4DB9 A;  2DB0 A;  2IW3 A;  3RZX A;  4CBA A;  3K64 A;  4CB9 A;  1M8Z A;  5KLA A;  4IMI A;  5HUW C;  3BTR C;  2Z6H A;  4I1E A;  2JKR B;  1V18 A;  5CL7 A;  3EA5 B;  3AU3 A;  5EKF A;  3K62 A;  2C1M A;  4ZDU A;  3K7W A;  3VLE A;  3ZIL A;  4H3H A;  2C1T A;  5H2W A;  4FZD A;  3A6P A;  4U5N A;  3VLF A;  4V3O A;  1Y2A C;  4I96 A;  3L6X A;  5CLA A;  1U6G C;  3LWW A;  3ZKV A;  4UAF B;  3Q0S A;  4G3A A;  1JPW A;  5CLD A;  4U3J C;  4A3V A;  4FZF A;  2Z5K A;  3FGA A;  3DW8 A;  4CRV B;  4PVZ A;  1W63 A;  5K6S A;  4HTV A;  3V6Y A;  4RZP A;  1LUJ A;  2XA7 A;  3GB8 A;  4EVA A;  3V71 A;  2RU4 B;  2YNS A;  4DZS A;  2NYL A;  2IAE B;  5FC8 E;  5BZ5 A;  3SLA A;  5KLR B;  3WOZ A;  4I37 A;  4RV1 A;  5CL8 A;  1PJM B;  1EE4 A;  1EJY I;  4D4E A;  2FV2 A;  2VGL B;  4DB8 A;  3EG5 B;  5BZV A;  4I2Z A;  3K4E A;  5SWF A;  4D49 A;  4UAD A;  3JX7 A;  4PLQ A;  4QMH A;  3IFQ A;  2Z5N A;  3OQS A;  4CRU B;  3VE6 A;  4DBA A;  1W9C A;  3WPT A;  2QMR A;  5BYM A;  5H2X A;  4I3N A;  4EV9 A;  1LRV A;  4JW2 B;  1Z2C B;  4GMO A;  5CLB A;  4MZ6 E;  3O2T A;  4QMJ A;  1F59 A;  4GMN A;  5K9S A;  4I2S A;  3RZ9 A;  4CB8 A;  4MFU A;  3WOY A;  3O2Q A;  4PLR A;  4UAE A;  4LAC A;  4U54 A;  2PF4 A;  5HHG E;  3QGC A;  5KL8 A;  2JAK A;  4L4H A;  4K6J A;  3NMZ A;  5KLT B;  4ADY A;  4R10 A;  3K49 A;  4WV6 A;  2H4M A;  3L3F X;  1UPK A;  3TJ3 A;  4L4I A;  4OO6 A;  4K92 A;  4B8J A;  5BZU A;  3C2H A;  4JLQ A;  5KL1 A;  4I8M A;  4P6Z G;  3GNI A;  5CL3 A;  2Q5D A;  1QBK B;  2IWH A;  4FZA A;  3ZIN A;  1BK6 A;  3Q0Q A;  2X19 B;  4EVP A;  3L3Q A;  1QZ7 A;  4JW3 C;  5E6Q B;  4I2W A;  3ZIK A;  3UL1 B;  2NPP B;  1WA5 C;  3GAE A;  4HNM A;  2QK2 A;  2PKG A;  3Q0M A;  4B8O A;  3DAD A;  3LTM A;  3UL0 B;  4UQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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