2IAEA

Crystal structure of a protein phosphatase 2a (pp2a) holoenzyme.
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
583
structure length
583
Chain Sequence
DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mus musculus
molecule keywords Serine/threonine-protein phosphatase 2A 65 kDa regulatory su
total genus 156
structure length 583
sequence length 583
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02985 HEAT HEAT repeat
A PF13646 HEAT_2 HEAT repeats
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat Variant 2iaeA01
1HO8A 1W9CA 2WTKA 5BZUA 2IX3A 2IAEA 3TX7A 3QG9A 5FC8E 3OUWA 2JAKA 2QK1A 5HHGE 5D5KC 3GQ2A 1UN0A 5EKFA 4YJLA 3EG5B 3Q0MA 2X1GF 4DJSA 1IQ1C 1T08A 3OPBA 4RXHB 5EKGA 3ODRA 2F31A 5H2XA 5SW9A 1M8YA 4U3JC 1JDHA 3IFQA 5K6SA 4V3QA 1TH1A 1Q1SC 4CT6B 2NYLA 4EV9A 3K61A 4KZGA 5J3VA 4I2ZA 3K7WA 2XA7B 3TT9A 3UKZB 1PJNB 3UL1B 2JDQA 5KLTB 2JKTB 4FZDA 3GRLA 3WYFC 5SVZA 4U5OA 3EA5B 3UL0B 1EE4A 4U58A 3O2SA 5HUYC 4FQ3A 4DVGB 3FEXC 1I7XA 1JPWA 1UKLA 3GAEA 2IE3A 1W63B 2P8QA 3C2GA 3W3UA 3V71A 3QGCA 2GL7A 1EJLI 3L6YA 4P6ZG 4V3RA 2OF3A 1B3UA 3OQSA 2VGLB 4A0CA 2BNXA 4H3KA 1M8XA 4U54A 4DB8A 1EE5A 3TJZB 4K6JA 3ZHPA 2BKUB 2YNRA 4BQKA 1BK5A 2RU4B 4PLSA 1XQRA 1IB2A 1F59A 3GS3A 5LSWA 4D4EA 1IBRB 4TNMA 3Q0QA 4QMIA 3GVOA 3BCTA 3Q0OA 3KNDA 3ZIQA 2NPPB 4MZ6E 1XM9A 2JKRA 1O6OA 4JLQA 5AEIA 5E6QB 3ZINA 4MFVA 4YJEA 1BK6A 4CRUB 4ZDUA 4U5UA 2DB0A 2OT8A 3RZXA 4MZ5E 5BZ5A 4B18A 2Z5OA 1UPLA 2IE4A 4EVPA 3AU3A 3NMXA 5KL1A 2XA7A 1M5NS 3BSBA 3QHEA 3BX3A 2JKTA 4QMHA 3Q0NA 2QK2A 2JKRB 3QMLC 4EVTA 4DB6A 3TPMA 3V74A 1PJMB 3Q0SA 4G3AA 3OUXA 4U5SA 4QMJA 2PKGA 3V6YA 4HNMA 3TPOA 1WA5C 1W63A 4I2WA 4CT7B 3ODSA 3Q0LA 2H4MA 4U5VA 1Z2CB 3C5WA 2IW3A 3GVTA 3UKXB 2IWHA 3UVUA 4CBAA 3L6XA 3K7VA 3WOYA 1QGKA 2VGLA 3Q5UA 3DW8A 4E4VA 4YI0C 3TJ3A 1QGRA 4I5LA 4MFUA 4UQIB 1LRVA 4GMOA 5BZ1A 2RU4A 1M8WA 4HM9A 4OIHA 4NZWA 2Z5NA 4D49A 1WA5B 3VWAA 3WOZA 4FFBC 2NPPA 2Q5DA 2YNSA 4CRVB 3FGAB 2Z5KA 2NYMB 5H2WA 1LUJA 4Y5JA 2Z5JA 4BA3A 4CB8A 4FZFA 3K5YA 3GNIA 5DN7A 2W3CA 3O2QA 3ZIOA 5CTTA 1Q1TC 3ND2A 4R0ZA 1UPKA 4R11A 3IBVA 5BYMA 3K4EA 3K49A 4B8JA 2YJYA 3NOWA 4EV8A 4R10A 1Y2AC 3L3FX 3T7UA 4UWXA 2Z6HA 1OYZA 3LTJA 2Z6GA 2BCTA 4U5LA 1QBKB 4CB9A 4PLQA 5KL8A 4EVAA 3QGBA 3Q0PA 2X19B 5KLRB 3UKYB 1QZ7A 5KLAA 3C2HA 4UQIA 4CV5B 1GCJA 3L3QA 3A6PA 1I7WA 4UAEA 4I5NA 4DB9A 3K64A 4WV6A 3NMZA 3ZKVA 1U6GC 4RZPA 1G3JA 5SWFA 4GMNA 3BX2A 3O4XA 2IAEB 4YGXA 3Q0RA 3RZ9A 3BWTA 4FDDA 5HUWC 2QMRA 4P6ZB 4HXTA 3K62A 2FV2A 2QNAA 3FGAA 4H3HA 4HTVA 4JW2B 1JPPA 4UAFB 3K5QA 2C1TA 1XQSA 2NYMA 4UADA 4V3OA 1M1EA 4B8PA 3LWWA 4BPLA 3EBBA 4K92A 4OO6A 3WPTA 3ZIPA 4IMIA 1V18A 3O2TA 3DADA 3FEYC 5B56A 3BTRC 4LACA 4RV1A 2NYLB 5BZVA 1O6PA 3GB8A 4O27A 4FZAA 2BAPA 2C1MA 4YK6A 3BSXA 1M8ZA 1IALA 3H3DX 3NMWA 4U5NA 5JJAA 4L7MA 3OBVA 3PSTA 4NEEA 2Z5MA 4DBAA 3UKWB 5EWPA 4ADYA 4XZRB 3K5ZA 4PVZA 5K9SA 3LTMA 1EJYI 3ZIRA 4PLRA 3VE6A 4B8OA 4DZSA 4IMJA 2PF4A 3PSPA
chains in the Genus database with same CATH superfamily
1HO8A 1W9CA 3SL9A 2WTKA 3UJ0A 5BZUA 2IX3A 2IAEA 3TX7A 3QG9A 5FC8E 3OUWA 2JAKA 2QK1A 5HHGE 5D5KC 3GQ2A 4JW2A 5CLCA 1UN0A 5EKFA 4YJLA 3EG5B 3Q0MA 2X1GF 4DJSA 1IQ1C 1T08A 3OPBA 4RXHB 5EKGA 3ODRA 2F31A 5H2XA 5SW9A 1M8YA 4U3JC 1JDHA 3IFQA 5K6SA 4V3QA 1TH1A 1Q1SC 4CT6B 2NYLA 4A3VA 4EV9A 3K61A 5CL8A 4KZGA 5J3VA 4I2ZA 3K7WA 2XA7B 3TT9A 3UKZB 1PJNB 3UL1B 2JDQA 5KLTB 2JKTB 4FZDA 3GRLA 3WYFC 5SVZA 3JY1A 4U5OA 3EA5B 3UL0B 1EE4A 4U58A 3O2SA 5HUYC 4FQ3A 4DVGB 3FEXC 1I7XA 1JPWA 1UKLA 4I3NA 3GAEA 2IE3A 1W63B 5CLDA 2P8QA 3ZIKA 3C2GA 3SLAA 3W3UA 3V71A 3QGCA 2GL7A 1EJLI 3L6YA 4P6ZG 4V3RA 2OF3A 1B3UA 3OQSA 1TE4A 4U2XD 2VGLB 4A0CA 2BNXA 4H3KA 1M8XA 4L4HA 4U54A 4DB8A 1EE5A 3TJZB 4I8MA 4K6JA 3ZHPA 2BKUB 2YNRA 4BQKA 1BK5A 2RU4B 4PLSA 1XQRA 1IB2A 1F59A 3GS3A 4I37A 4FP7A 5LSWA 4D4EA 1IBRB 4TNMA 3Q0QA 4QMIA 3GVOA 3BCTA 3Q0OA 3KNDA 3ZIQA 2NPPB 4MZ6E 1XM9A 2JKRA 1O6OA 4JLQA 4JW3C 5AEIA 5E6QB 3ZINA 4MFVA 4YJEA 1BK6A 4CRUB 4ZDUA 4U5UA 2DB0A 2OT8A 3RZXA 4MZ5E 5BZ5A 4B18A 2Z5OA 1UPLA 2IE4A 4EVPA 3AU3A 3NMXA 5KL1A 2XA7A 1M5NS 3BSBA 3QHEA 3BX3A 2JKTA 4QMHA 3Q0NA 2QK2A 2JKRB 3QMLC 4EVTA 4DB6A 3TPMA 3V74A 1PJMB 3Q0SA 4G3AA 4I0YA 3OUXA 4U5SA 4QMJA 2PKGA 3V6YA 3UJ4A 4HNMA 3TPOA 1WA5C 1W63A 4I2WA 3ODSA 4CT7B 3Q0LA 2H4MA 4U5VA 5CLAA 1Z2CB 3C5WA 2IW3A 3GVTA 3UKXB 2IWHA 3UVUA 4CBAA 4I96A 3L6XA 3K7VA 3WOYA 1QGKA 5CL4A 2VGLA 3Q5UA 3DW8A 4E4VA 4YI0C 3TJ3A 3JXZA 1QGRA 4I5LA 4MFUA 4UQIB 1LRVA 4GMOA 5BZ1A 5CLBA 2RU4A 1M8WA 4HM9A 4OIHA 4NZWA 2Z5NA 4D49A 1WA5B 3VWAA 3WOZA 4FFBC 5CL5A 2NPPA 2Q5DA 4I1EA 5KUBA 2YNSA 4JKQA 4CRVB 3FGAB 3JX7A 2Z5KA 2NYMB 5H2WA 3VLFA 1LUJA 4Y5JA 2Z5JA 4BA3A 4CB8A 4FZFA 3K5YA 3GNIA 5DN7A 2W3CA 3O2QA 3ZIOA 5CTTA 1Q1TC 3ND2A 4R0ZA 3BVSA 1LSHA 1UPKA 4R11A 3IBVA 5BYMA 5CL3A 3K4EA 3K49A 4B8JA 2YJYA 3NOWA 4EV8A 4R10A 3VLEA 1Y2AC 3L3FX 3T7UA 4I2SA 4UWXA 1N4KA 2Z6HA 1OYZA 3LTJA 2Z6GA 5CL6A 2BCTA 4U5LA 3ZILA 1QBKB 4CB9A 4PLQA 5KL8A 4EVAA 3QGBA 3Q0PA 2X19B 5KLRB 3UKYB 1QZ7A 5KLAA 3C2HA 4UQIA 4CV5B 4I7IA 1GCJA 3L3QA 3A6PA 1I7WA 4UAEA 4I5NA 4DB9A 3K64A 4WV6A 3NMZA 3ZKVA 1U6GC 4RZPA 1G3JA 5SWFA 4GMNA 3BX2A 5CLEA 3O4XA 2IAEB 4YGXA 3Q0RA 3RZ9A 3BWTA 4FDDA 5HUWC 2QMRA 4P6ZB 4HXTA 3K62A 2FV2A 2QNAA 3FGAA 4H3HA 4HTVA 4JW2B 1JPPA 4UAFB 3K5QA 2C1TA 1XQSA 5CL7A 2NYMA 4UADA 4V3OA 1M1EA 4B8PA 3LWWA 4BPLA 3EBBA 4K92A 4OO6A 3WPTA 3ZIPA 4IMIA 2XOAA 1V18A 3O2TA 3DADA 3FEYC 4L4IA 5B56A 4I6IA 3BTRC 4LACA 4RV1A 2NYLB 5BZVA 3JXYA 1O6PA 3GB8A 4O27A 4FZAA 2BAPA 2C1MA 4YK6A 3BSXA 1M8ZA 1IALA 3H3DX 3NMWA 4U5NA 5JJAA 4L7MA 3OBVA 3PSTA 4NEEA 2Z5MA 4DBAA 3UKWB 5CL9A 5EWPA 4ADYA 4XZRB 3K5ZA 4PVZA 5K9SA 3LTMA 1EJYI 3ZIRA 3T8SA 4PLRA 4A3TA 3VE6A 4B8OA 3VLDA 4DZSA 4IMJA 2PF4A 3PSPA
chains in the Genus database with same CATH topology
1HO8A 1W9CA 3SL9A 2WTKA 5BZUA 2IX3A 2IAEA 3TX7A 3QG9A 5FC8E 3OUWA 2JAKA 2QK1A 5HHGE 5D5KC 3GQ2A 4JW2A 5CLCA 1UN0A 5EKFA 4YJLA 3EG5B 3Q0MA 2X1GF 4DJSA 1IQ1C 1T08A 3OPBA 4RXHB 5EKGA 3ODRA 2F31A 5H2XA 5SW9A 1M8YA 4U3JC 1JDHA 3IFQA 5K6SA 4V3QA 1TH1A 1Q1SC 4CT6B 2NYLA 4A3VA 4EV9A 3K61A 5CL8A 4KZGA 5J3VA 4I2ZA 3K7WA 2XA7B 3TT9A 3UKZB 1PJNB 3UL1B 2JDQA 5KLTB 2JKTB 4FZDA 3GRLA 3WYFC 5SVZA 3JY1A 4U5OA 3EA5B 3UL0B 1EE4A 4U58A 3O2SA 5HUYC 4FQ3A 4DVGB 3FEXC 1I7XA 1JPWA 1UKLA 4I3NA 3GAEA 2IE3A 1W63B 5CLDA 2P8QA 3ZIKA 3C2GA 3SLAA 3W3UA 3V71A 3QGCA 2GL7A 1EJLI 3L6YA 4P6ZG 4V3RA 2OF3A 1B3UA 3OQSA 1TE4A 4U2XD 2VGLB 4A0CA 2BNXA 4H3KA 1M8XA 4L4HA 4U54A 4DB8A 1EE5A 3TJZB 4I8MA 4K6JA 3ZHPA 2BKUB 2YNRA 4BQKA 1BK5A 2RU4B 4PLSA 1XQRA 1IB2A 1F59A 3GS3A 4I37A 4FP7A 5LSWA 4D4EA 1IBRB 4TNMA 3Q0QA 4QMIA 3GVOA 3BCTA 3Q0OA 3KNDA 3ZIQA 2NPPB 4MZ6E 1XM9A 2JKRA 1O6OA 4JLQA 4JW3C 5AEIA 5E6QB 3ZINA 4MFVA 4YJEA 1BK6A 4CRUB 4ZDUA 4U5UA 2DB0A 2OT8A 3RZXA 4MZ5E 5BZ5A 4B18A 2Z5OA 1UPLA 2IE4A 4EVPA 3AU3A 3NMXA 5KL1A 2XA7A 1M5NS 3BSBA 3QHEA 3BX3A 2JKTA 4QMHA 3Q0NA 2QK2A 2JKRB 3QMLC 4EVTA 4DB6A 3TPMA 3V74A 1PJMB 3Q0SA 4G3AA 4I0YA 3OUXA 4U5SA 4QMJA 2PKGA 3V6YA 4HNMA 3TPOA 1WA5C 1W63A 4I2WA 3ODSA 4CT7B 3Q0LA 2H4MA 4U5VA 5CLAA 1Z2CB 3C5WA 2IW3A 3GVTA 3UKXB 2IWHA 3UVUA 4CBAA 4I96A 3L6XA 3K7VA 3WOYA 1QGKA 5CL4A 2VGLA 3Q5UA 3DW8A 4E4VA 4YI0C 3TJ3A 3JXZA 1QGRA 4I5LA 4MFUA 4UQIB 1LRVA 4GMOA 5BZ1A 5CLBA 2RU4A 1M8WA 4HM9A 4OIHA 4NZWA 2Z5NA 4D49A 1WA5B 3VWAA 3WOZA 4FFBC 5CL5A 2NPPA 2Q5DA 4I1EA 5KUBA 2YNSA 4JKQA 4CRVB 3FGAB 3JX7A 2Z5KA 2NYMB 5H2WA 3VLFA 1LUJA 4Y5JA 2Z5JA 4BA3A 4CB8A 4FZFA 3K5YA 3GNIA 5DN7A 2W3CA 3O2QA 3ZIOA 5CTTA 1Q1TC 3ND2A 4R0ZA 3BVSA 1UPKA 4R11A 3IBVA 5BYMA 5CL3A 3K4EA 3K49A 4B8JA 2YJYA 3NOWA 4EV8A 4R10A 3VLEA 1Y2AC 3L3FX 3T7UA 4I2SA 4UWXA 2Z6HA 1OYZA 3LTJA 2Z6GA 5CL6A 2BCTA 4U5LA 3ZILA 1QBKB 4CB9A 4PLQA 5KL8A 4EVAA 3QGBA 3Q0PA 2X19B 5KLRB 3UKYB 1QZ7A 5KLAA 3C2HA 4UQIA 4CV5B 4I7IA 1GCJA 3L3QA 3A6PA 1I7WA 4UAEA 4I5NA 4DB9A 3K64A 4WV6A 3NMZA 3ZKVA 1U6GC 4RZPA 1G3JA 5SWFA 4GMNA 3BX2A 5CLEA 3O4XA 2IAEB 4YGXA 3Q0RA 3RZ9A 3BWTA 4FDDA 5HUWC 2QMRA 4P6ZB 4HXTA 3K62A 2FV2A 2QNAA 3FGAA 4H3HA 4HTVA 4JW2B 1JPPA 4UAFB 3K5QA 2C1TA 1XQSA 5CL7A 2NYMA 4UADA 4V3OA 1M1EA 4B8PA 3LWWA 4BPLA 3EBBA 4K92A 4OO6A 3WPTA 3ZIPA 4IMIA 2XOAA 1V18A 3O2TA 3DADA 3FEYC 4L4IA 5B56A 4I6IA 3BTRC 4LACA 4RV1A 2NYLB 5BZVA 3JXYA 1O6PA 3GB8A 4O27A 4FZAA 2BAPA 2C1MA 4YK6A 3BSXA 1M8ZA 1IALA 3H3DX 3NMWA 4U5NA 5JJAA 4L7MA 3OBVA 3PSTA 4NEEA 2Z5MA 4DBAA 3UKWB 5CL9A 5EWPA 4ADYA 4XZRB 3K5ZA 4PVZA 5K9SA 3LTMA 1EJYI 3ZIRA 4PLRA 4A3TA 3VE6A 4B8OA 3VLDA 4DZSA 4IMJA 2PF4A 3PSPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HO8 A;  1W9C A;  2WTK A;  5BZU A;  2IX3 A;  2IAE A;  3TX7 A;  3QG9 A;  5FC8 E;  3OUW A;  2JAK A;  2QK1 A;  5HHG E;  5D5K C;  3GQ2 A;  1UN0 A;  5EKF A;  4YJL A;  3EG5 B;  3Q0M A;  2X1G F;  4DJS A;  1IQ1 C;  1T08 A;  3OPB A;  4RXH B;  5EKG A;  3ODR A;  2F31 A;  5H2X A;  5SW9 A;  1M8Y A;  4U3J C;  1JDH A;  3IFQ A;  5K6S A;  4V3Q A;  1TH1 A;  1Q1S C;  4CT6 B;  2NYL A;  4EV9 A;  3K61 A;  4KZG A;  5J3V A;  4I2Z A;  3K7W A;  2XA7 B;  3TT9 A;  3UKZ B;  1PJN B;  3UL1 B;  2JDQ A;  5KLT B;  2JKT B;  4FZD A;  3GRL A;  3WYF C;  5SVZ A;  4U5O A;  3EA5 B;  3UL0 B;  1EE4 A;  4U58 A;  3O2S A;  5HUY C;  4FQ3 A;  4DVG B;  3FEX C;  1I7X A;  1JPW A;  1UKL A;  3GAE A;  2IE3 A;  1W63 B;  2P8Q A;  3C2G A;  3W3U A;  3V71 A;  3QGC A;  2GL7 A;  1EJL I;  3L6Y A;  4P6Z G;  4V3R A;  2OF3 A;  1B3U A;  3OQS A;  2VGL B;  4A0C A;  2BNX A;  4H3K A;  1M8X A;  4U54 A;  4DB8 A;  1EE5 A;  3TJZ B;  4K6J A;  3ZHP A;  2BKU B;  2YNR A;  4BQK A;  1BK5 A;  2RU4 B;  4PLS A;  1XQR A;  1IB2 A;  1F59 A;  3GS3 A;  5LSW A;  4D4E A;  1IBR B;  4TNM A;  3Q0Q A;  4QMI A;  3GVO A;  3BCT A;  3Q0O A;  3KND A;  3ZIQ A;  2NPP B;  4MZ6 E;  1XM9 A;  2JKR A;  1O6O A;  4JLQ A;  5AEI A;  5E6Q B;  3ZIN A;  4MFV A;  4YJE A;  1BK6 A;  4CRU B;  4ZDU A;  4U5U A;  2DB0 A;  2OT8 A;  3RZX A;  4MZ5 E;  5BZ5 A;  4B18 A;  2Z5O A;  1UPL A;  2IE4 A;  4EVP A;  3AU3 A;  3NMX A;  5KL1 A;  2XA7 A;  1M5N S;  3BSB A;  3QHE A;  3BX3 A;  2JKT A;  4QMH A;  3Q0N A;  2QK2 A;  2JKR B;  3QML C;  4EVT A;  4DB6 A;  3TPM A;  3V74 A;  1PJM B;  3Q0S A;  4G3A A;  3OUX A;  4U5S A;  4QMJ A;  2PKG A;  3V6Y A;  4HNM A;  3TPO A;  1WA5 C;  1W63 A;  4I2W A;  4CT7 B;  3ODS A;  3Q0L A;  2H4M A;  4U5V A;  1Z2C B;  3C5W A;  2IW3 A;  3GVT A;  3UKX B;  2IWH A;  3UVU A;  4CBA A;  3L6X A;  3K7V A;  3WOY A;  1QGK A;  2VGL A;  3Q5U A;  3DW8 A;  4E4V A;  4YI0 C;  3TJ3 A;  1QGR A;  4I5L A;  4MFU A;  4UQI B;  1LRV A;  4GMO A;  5BZ1 A;  2RU4 A;  1M8W A;  4HM9 A;  4OIH A;  4NZW A;  2Z5N A;  4D49 A;  1WA5 B;  3VWA A;  3WOZ A;  4FFB C;  2NPP A;  2Q5D A;  2YNS A;  4CRV B;  3FGA B;  2Z5K A;  2NYM B;  5H2W A;  1LUJ A;  4Y5J A;  2Z5J A;  4BA3 A;  4CB8 A;  4FZF A;  3K5Y A;  3GNI A;  5DN7 A;  2W3C A;  3O2Q A;  3ZIO A;  5CTT A;  1Q1T C;  3ND2 A;  4R0Z A;  1UPK A;  4R11 A;  3IBV A;  5BYM A;  3K4E A;  3K49 A;  4B8J A;  2YJY A;  3NOW A;  4EV8 A;  4R10 A;  1Y2A C;  3L3F X;  3T7U A;  4UWX A;  2Z6H A;  1OYZ A;  3LTJ A;  2Z6G A;  2BCT A;  4U5L A;  1QBK B;  4CB9 A;  4PLQ A;  5KL8 A;  4EVA A;  3QGB A;  3Q0P A;  2X19 B;  5KLR B;  3UKY B;  1QZ7 A;  5KLA A;  3C2H A;  4UQI A;  4CV5 B;  1GCJ A;  3L3Q A;  3A6P A;  1I7W A;  4UAE A;  4I5N A;  4DB9 A;  3K64 A;  4WV6 A;  3NMZ A;  3ZKV A;  1U6G C;  4RZP A;  1G3J A;  5SWF A;  4GMN A;  3BX2 A;  3O4X A;  2IAE B;  4YGX A;  3Q0R A;  3RZ9 A;  3BWT A;  4FDD A;  5HUW C;  2QMR A;  4P6Z B;  4HXT A;  3K62 A;  2FV2 A;  2QNA A;  3FGA A;  4H3H A;  4HTV A;  4JW2 B;  1JPP A;  4UAF B;  3K5Q A;  2C1T A;  1XQS A;  2NYM A;  4UAD A;  4V3O A;  1M1E A;  4B8P A;  3LWW A;  4BPL A;  3EBB A;  4K92 A;  4OO6 A;  3WPT A;  3ZIP A;  4IMI A;  1V18 A;  3O2T A;  3DAD A;  3FEY C;  5B56 A;  3BTR C;  4LAC A;  4RV1 A;  2NYL B;  5BZV A;  1O6P A;  3GB8 A;  4O27 A;  4FZA A;  2BAP A;  2C1M A;  4YK6 A;  3BSX A;  1M8Z A;  1IAL A;  3H3D X;  3NMW A;  4U5N A;  5JJA A;  4L7M A;  3OBV A;  3PST A;  4NEE A;  2Z5M A;  4DBA A;  3UKW B;  5EWP A;  4ADY A;  4XZR B;  3K5Z A;  4PVZ A;  5K9S A;  3LTM A;  1EJY I;  3ZIR A;  4PLR A;  3VE6 A;  4B8O A;  4DZS A;  4IMJ A;  2PF4 A;  3PSP A; 
#chains in the Genus database with same CATH topology
 1HO8 A;  1W9C A;  3SL9 A;  2WTK A;  3UJ0 A;  5BZU A;  2IX3 A;  2IAE A;  3TX7 A;  3QG9 A;  5FC8 E;  3OUW A;  2JAK A;  2QK1 A;  5HHG E;  5D5K C;  3GQ2 A;  4JW2 A;  5CLC A;  1UN0 A;  5EKF A;  4YJL A;  3EG5 B;  3Q0M A;  2X1G F;  4DJS A;  1IQ1 C;  1T08 A;  3OPB A;  4RXH B;  5EKG A;  3ODR A;  2F31 A;  5H2X A;  5SW9 A;  1M8Y A;  4U3J C;  1JDH A;  3IFQ A;  5K6S A;  4V3Q A;  1TH1 A;  1Q1S C;  4CT6 B;  2NYL A;  4A3V A;  4EV9 A;  3K61 A;  5CL8 A;  4KZG A;  5J3V A;  4I2Z A;  3K7W A;  2XA7 B;  3TT9 A;  3UKZ B;  1PJN B;  3UL1 B;  2JDQ A;  5KLT B;  2JKT B;  4FZD A;  3GRL A;  3WYF C;  5SVZ A;  3JY1 A;  4U5O A;  3EA5 B;  3UL0 B;  1EE4 A;  4U58 A;  3O2S A;  5HUY C;  4FQ3 A;  4DVG B;  3FEX C;  1I7X A;  1JPW A;  1UKL A;  4I3N A;  3GAE A;  2IE3 A;  1W63 B;  5CLD A;  2P8Q A;  3ZIK A;  3C2G A;  3SLA A;  3W3U A;  3V71 A;  3QGC A;  2GL7 A;  1EJL I;  3L6Y A;  4P6Z G;  4V3R A;  2OF3 A;  1B3U A;  3OQS A;  1TE4 A;  4U2X D;  2VGL B;  4A0C A;  2BNX A;  4H3K A;  1M8X A;  4L4H A;  4U54 A;  4DB8 A;  1EE5 A;  3TJZ B;  4I8M A;  4K6J A;  3ZHP A;  2BKU B;  2YNR A;  4BQK A;  1BK5 A;  2RU4 B;  4PLS A;  1XQR A;  1IB2 A;  1F59 A;  3GS3 A;  4I37 A;  4FP7 A;  5LSW A;  4D4E A;  1IBR B;  4TNM A;  3Q0Q A;  4QMI A;  3GVO A;  3BCT A;  3Q0O A;  3KND A;  3ZIQ A;  2NPP B;  4MZ6 E;  1XM9 A;  2JKR A;  1O6O A;  4JLQ A;  4JW3 C;  5AEI A;  5E6Q B;  3ZIN A;  4MFV A;  4YJE A;  1BK6 A;  4CRU B;  4ZDU A;  4U5U A;  2DB0 A;  2OT8 A;  3RZX A;  4MZ5 E;  5BZ5 A;  4B18 A;  2Z5O A;  1UPL A;  2IE4 A;  4EVP A;  3AU3 A;  3NMX A;  5KL1 A;  2XA7 A;  1M5N S;  3BSB A;  3QHE A;  3BX3 A;  2JKT A;  4QMH A;  3Q0N A;  2QK2 A;  2JKR B;  3QML C;  4EVT A;  4DB6 A;  3TPM A;  3V74 A;  1PJM B;  3Q0S A;  4G3A A;  4I0Y A;  3OUX A;  4U5S A;  4QMJ A;  2PKG A;  3V6Y A;  3UJ4 A;  4HNM A;  3TPO A;  1WA5 C;  1W63 A;  4I2W A;  3ODS A;  4CT7 B;  3Q0L A;  2H4M A;  4U5V A;  5CLA A;  1Z2C B;  3C5W A;  2IW3 A;  3GVT A;  3UKX B;  2IWH A;  3UVU A;  4CBA A;  4I96 A;  3L6X A;  3K7V A;  3WOY A;  1QGK A;  5CL4 A;  2VGL A;  3Q5U A;  3DW8 A;  4E4V A;  4YI0 C;  3TJ3 A;  3JXZ A;  1QGR A;  4I5L A;  4MFU A;  4UQI B;  1LRV A;  4GMO A;  5BZ1 A;  5CLB A;  2RU4 A;  1M8W A;  4HM9 A;  4OIH A;  4NZW A;  2Z5N A;  4D49 A;  1WA5 B;  3VWA A;  3WOZ A;  4FFB C;  5CL5 A;  2NPP A;  2Q5D A;  4I1E A;  5KUB A;  2YNS A;  4JKQ A;  4CRV B;  3FGA B;  3JX7 A;  2Z5K A;  2NYM B;  5H2W A;  3VLF A;  1LUJ A;  4Y5J A;  2Z5J A;  4BA3 A;  4CB8 A;  4FZF A;  3K5Y A;  3GNI A;  5DN7 A;  2W3C A;  3O2Q A;  3ZIO A;  5CTT A;  1Q1T C;  3ND2 A;  4R0Z A;  3BVS A;  1LSH A;  1UPK A;  4R11 A;  3IBV A;  5BYM A;  5CL3 A;  3K4E A;  3K49 A;  4B8J A;  2YJY A;  3NOW A;  4EV8 A;  4R10 A;  3VLE A;  1Y2A C;  3L3F X;  3T7U A;  4I2S A;  4UWX A;  1N4K A;  2Z6H A;  1OYZ A;  3LTJ A;  2Z6G A;  5CL6 A;  2BCT A;  4U5L A;  3ZIL A;  1QBK B;  4CB9 A;  4PLQ A;  5KL8 A;  4EVA A;  3QGB A;  3Q0P A;  2X19 B;  5KLR B;  3UKY B;  1QZ7 A;  5KLA A;  3C2H A;  4UQI A;  4CV5 B;  4I7I A;  1GCJ A;  3L3Q A;  3A6P A;  1I7W A;  4UAE A;  4I5N A;  4DB9 A;  3K64 A;  4WV6 A;  3NMZ A;  3ZKV A;  1U6G C;  4RZP A;  1G3J A;  5SWF A;  4GMN A;  3BX2 A;  5CLE A;  3O4X A;  2IAE B;  4YGX A;  3Q0R A;  3RZ9 A;  3BWT A;  4FDD A;  5HUW C;  2QMR A;  4P6Z B;  4HXT A;  3K62 A;  2FV2 A;  2QNA A;  3FGA A;  4H3H A;  4HTV A;  4JW2 B;  1JPP A;  4UAF B;  3K5Q A;  2C1T A;  1XQS A;  5CL7 A;  2NYM A;  4UAD A;  4V3O A;  1M1E A;  4B8P A;  3LWW A;  4BPL A;  3EBB A;  4K92 A;  4OO6 A;  3WPT A;  3ZIP A;  4IMI A;  2XOA A;  1V18 A;  3O2T A;  3DAD A;  3FEY C;  4L4I A;  5B56 A;  4I6I A;  3BTR C;  4LAC A;  4RV1 A;  2NYL B;  5BZV A;  3JXY A;  1O6P A;  3GB8 A;  4O27 A;  4FZA A;  2BAP A;  2C1M A;  4YK6 A;  3BSX A;  1M8Z A;  1IAL A;  3H3D X;  3NMW A;  4U5N A;  5JJA A;  4L7M A;  3OBV A;  3PST A;  4NEE A;  2Z5M A;  4DBA A;  3UKW B;  5CL9 A;  5EWP A;  4ADY A;  4XZR B;  3K5Z A;  4PVZ A;  5K9S A;  3LTM A;  1EJY I;  3ZIR A;  3T8S A;  4PLR A;  4A3T A;  3VE6 A;  4B8O A;  3VLD A;  4DZS A;  4IMJ A;  2PF4 A;  3PSP A; 
#chains in the Genus database with same CATH homology
 1HO8 A;  1W9C A;  3SL9 A;  2WTK A;  5BZU A;  2IX3 A;  2IAE A;  3TX7 A;  3QG9 A;  5FC8 E;  3OUW A;  2JAK A;  2QK1 A;  5HHG E;  5D5K C;  3GQ2 A;  4JW2 A;  5CLC A;  1UN0 A;  5EKF A;  4YJL A;  3EG5 B;  3Q0M A;  2X1G F;  4DJS A;  1IQ1 C;  1T08 A;  3OPB A;  4RXH B;  5EKG A;  3ODR A;  2F31 A;  5H2X A;  5SW9 A;  1M8Y A;  4U3J C;  1JDH A;  3IFQ A;  5K6S A;  4V3Q A;  1TH1 A;  1Q1S C;  4CT6 B;  2NYL A;  4A3V A;  4EV9 A;  3K61 A;  5CL8 A;  4KZG A;  5J3V A;  4I2Z A;  3K7W A;  2XA7 B;  3TT9 A;  3UKZ B;  1PJN B;  3UL1 B;  2JDQ A;  5KLT B;  2JKT B;  4FZD A;  3GRL A;  3WYF C;  5SVZ A;  3JY1 A;  4U5O A;  3EA5 B;  3UL0 B;  1EE4 A;  4U58 A;  3O2S A;  5HUY C;  4FQ3 A;  4DVG B;  3FEX C;  1I7X A;  1JPW A;  1UKL A;  4I3N A;  3GAE A;  2IE3 A;  1W63 B;  5CLD A;  2P8Q A;  3ZIK A;  3C2G A;  3SLA A;  3W3U A;  3V71 A;  3QGC A;  2GL7 A;  1EJL I;  3L6Y A;  4P6Z G;  4V3R A;  2OF3 A;  1B3U A;  3OQS A;  1TE4 A;  4U2X D;  2VGL B;  4A0C A;  2BNX A;  4H3K A;  1M8X A;  4L4H A;  4U54 A;  4DB8 A;  1EE5 A;  3TJZ B;  4I8M A;  4K6J A;  3ZHP A;  2BKU B;  2YNR A;  4BQK A;  1BK5 A;  2RU4 B;  4PLS A;  1XQR A;  1IB2 A;  1F59 A;  3GS3 A;  4I37 A;  4FP7 A;  5LSW A;  4D4E A;  1IBR B;  4TNM A;  3Q0Q A;  4QMI A;  3GVO A;  3BCT A;  3Q0O A;  3KND A;  3ZIQ A;  2NPP B;  4MZ6 E;  1XM9 A;  2JKR A;  1O6O A;  4JLQ A;  4JW3 C;  5AEI A;  5E6Q B;  3ZIN A;  4MFV A;  4YJE A;  1BK6 A;  4CRU B;  4ZDU A;  4U5U A;  2DB0 A;  2OT8 A;  3RZX A;  4MZ5 E;  5BZ5 A;  4B18 A;  2Z5O A;  1UPL A;  2IE4 A;  4EVP A;  3AU3 A;  3NMX A;  5KL1 A;  2XA7 A;  1M5N S;  3BSB A;  3QHE A;  3BX3 A;  2JKT A;  4QMH A;  3Q0N A;  2QK2 A;  2JKR B;  3QML C;  4EVT A;  4DB6 A;  3TPM A;  3V74 A;  1PJM B;  3Q0S A;  4G3A A;  4I0Y A;  3OUX A;  4U5S A;  4QMJ A;  2PKG A;  3V6Y A;  4HNM A;  3TPO A;  1WA5 C;  1W63 A;  4I2W A;  3ODS A;  4CT7 B;  3Q0L A;  2H4M A;  4U5V A;  5CLA A;  1Z2C B;  3C5W A;  2IW3 A;  3GVT A;  3UKX B;  2IWH A;  3UVU A;  4CBA A;  4I96 A;  3L6X A;  3K7V A;  3WOY A;  1QGK A;  5CL4 A;  2VGL A;  3Q5U A;  3DW8 A;  4E4V A;  4YI0 C;  3TJ3 A;  3JXZ A;  1QGR A;  4I5L A;  4MFU A;  4UQI B;  1LRV A;  4GMO A;  5BZ1 A;  5CLB A;  2RU4 A;  1M8W A;  4HM9 A;  4OIH A;  4NZW A;  2Z5N A;  4D49 A;  1WA5 B;  3VWA A;  3WOZ A;  4FFB C;  5CL5 A;  2NPP A;  2Q5D A;  4I1E A;  5KUB A;  2YNS A;  4JKQ A;  4CRV B;  3FGA B;  3JX7 A;  2Z5K A;  2NYM B;  5H2W A;  3VLF A;  1LUJ A;  4Y5J A;  2Z5J A;  4BA3 A;  4CB8 A;  4FZF A;  3K5Y A;  3GNI A;  5DN7 A;  2W3C A;  3O2Q A;  3ZIO A;  5CTT A;  1Q1T C;  3ND2 A;  4R0Z A;  3BVS A;  1UPK A;  4R11 A;  3IBV A;  5BYM A;  5CL3 A;  3K4E A;  3K49 A;  4B8J A;  2YJY A;  3NOW A;  4EV8 A;  4R10 A;  3VLE A;  1Y2A C;  3L3F X;  3T7U A;  4I2S A;  4UWX A;  2Z6H A;  1OYZ A;  3LTJ A;  2Z6G A;  5CL6 A;  2BCT A;  4U5L A;  3ZIL A;  1QBK B;  4CB9 A;  4PLQ A;  5KL8 A;  4EVA A;  3QGB A;  3Q0P A;  2X19 B;  5KLR B;  3UKY B;  1QZ7 A;  5KLA A;  3C2H A;  4UQI A;  4CV5 B;  4I7I A;  1GCJ A;  3L3Q A;  3A6P A;  1I7W A;  4UAE A;  4I5N A;  4DB9 A;  3K64 A;  4WV6 A;  3NMZ A;  3ZKV A;  1U6G C;  4RZP A;  1G3J A;  5SWF A;  4GMN A;  3BX2 A;  5CLE A;  3O4X A;  2IAE B;  4YGX A;  3Q0R A;  3RZ9 A;  3BWT A;  4FDD A;  5HUW C;  2QMR A;  4P6Z B;  4HXT A;  3K62 A;  2FV2 A;  2QNA A;  3FGA A;  4H3H A;  4HTV A;  4JW2 B;  1JPP A;  4UAF B;  3K5Q A;  2C1T A;  1XQS A;  5CL7 A;  2NYM A;  4UAD A;  4V3O A;  1M1E A;  4B8P A;  3LWW A;  4BPL A;  3EBB A;  4K92 A;  4OO6 A;  3WPT A;  3ZIP A;  4IMI A;  2XOA A;  1V18 A;  3O2T A;  3DAD A;  3FEY C;  4L4I A;  5B56 A;  4I6I A;  3BTR C;  4LAC A;  4RV1 A;  2NYL B;  5BZV A;  3JXY A;  1O6P A;  3GB8 A;  4O27 A;  4FZA A;  2BAP A;  2C1M A;  4YK6 A;  3BSX A;  1M8Z A;  1IAL A;  3H3D X;  3NMW A;  4U5N A;  5JJA A;  4L7M A;  3OBV A;  3PST A;  4NEE A;  2Z5M A;  4DBA A;  3UKW B;  5CL9 A;  5EWP A;  4ADY A;  4XZR B;  3K5Z A;  4PVZ A;  5K9S A;  3LTM A;  1EJY I;  3ZIR A;  4PLR A;  4A3T A;  3VE6 A;  4B8O A;  3VLD A;  4DZS A;  4IMJ A;  2PF4 A;  3PSP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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