2W3VA

Mycobacterium avium dihydrofolate reductase complexed with nadph and trimethoprim
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
165
structure length
165
Chain Sequence
RAEVGLVWAQSTSGVIGRGGDIPWSVPEDLTRFKEVTMGHTVIMGRRTWESLPAKVRPLPGRRNVVVSRRPDFVAEGARVAGSLEAALAYAGSDPAPWVIGGAQIYLLALPHATRCEVTEIEIDLRRDDDDALAPALDDSWVGETGEWLASRSGLRYRFHSYRRD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
rcsb
molecule tags Oxidoreductase
source organism Mycobacterium avium
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 47
structure length 165
sequence length 165
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 2w3vA00
4XRBA 3M09A 4X5GA 3EX8A 3SQYX 3FQZA 1RB3A 3QG2A 3FQ0A 4XECX 3FL8A 1RF7A 3F0UX 1OHJA 3SA1A 1DISA 4IXED 3K2HA 3KJSA 4HA7A 4M7VA 1S3VA 4FGGA 1DRBA 1PD8A 5U26A 3TQAA 3QLXA 2GD9A 5CC9A 2BLBA 2W3BA 1U72A 3QLYA 3RO9A 1DRHA 2W3VA 4Q0EA 1PD9A 3UM5A 1DYIA 3DAUA 3K74A 4IXFX 2OIPA 3TQBA 4X5IA 4XT6A 1M7AA 2CD2A 4PSSA 1DHJA 1SEJA 1VJ3A 4HOEA 4KAKA 4QLGA 3FYVX 1DHIA 1DDSA 3FQFA 3JWFA 3GHVA 4KL9A 3KY8A 4KJJA 1J3KA 1YHOA 3EELA 4LAEX 3NTZA 4NX6A 1D1GA 3QGTA 4OSGA 3Q1HA 1DR6A 4KLXA 1TDRA 1J3JA 3L3RA 3D80A 3NXOA 5ECCA 3F0VX 3EEMA 3DG8A 4QLFA 3DL6A 1JUVA 3JWKA 3JWMA 1RC4A 3NZDA 3IA5A 3F8YA 3GYFA 5JA3A 3FYWX 1DR3A 1AI9A 3FREX 1DG5A 1DLRA 5HT5A 5CCCA 1RX8A 1IA3A 1HFPA 2KGKA 3IRNA 2W3MA 1ZDRA 3FRFX 2W9GA 2W3AA 1HFRA 4PSYA 1RA2A 2W9TA 1MVTA 1RA8A 1KLKA 4M6LA 5HF2X 1DG7A 2ITHA 2INQA 2W9SA 4DP3A 3EEJA 4KJKA 1S3WA 3QLSA 1DYHA 4LEKX 2ANOA 2FZIA 1CD2A 4X5FA 3QYLA 2W3WA 4QHVA 4KNEA 4GH8A 4I13A 5HF0X 3HBBA 4ELHA 3K47A 4HOFA 4IXGX 4HOGA 3FY9X 2D5NA 3NZ6X 1DYRA 1RA1A 2W9HA 3FQVA 1DG8A 4H95A 4Q6AA 3GHCA 2B3ZA 3GI2A 1RD7A 1QZFA 4G95A 2LF1A 3JW3A 4LAHX 1RE7A 4LAGX 3QLZA 3ZPGA 2ZZAA 1KMSA 3INVA 3DRCA 2BLCA 8DFRA 3F0XX 3E0BA 4EIZA 5HVEA 3LG4A 6DFRA 3FRDX 1DDRA 3QL3A 4KD7A 3SRSX 2AZNA 5HQZA 3NXTA 3TD8A 4QJCA 3OAFA 3SGYA 3JTWA 4H98A 4ECKA 3K45A 1RX3A 1U70A 3CD2A 3DFRA 4Q67A 3S7AA 1M79A 1RH3A 3KJRA 1DYJA 4G3MA 1DF7A 1HFQA 1DAJA 5ECXA 3DATA 2H2QA 1PDBA 4P3QA 3SAIA 3IRMA 4Q0DA 3FRAX 1JOMA 5HPBA 2CIGA 3D84X 7DFRA 3JW5A 3SRRX 1RX5A 3F91A 3I3RA 1BZFA 3CL9A 1RX1A 2HQPA 2JYBA 2C2SA 3FQCA 2L28A 3NXRA 3TQ8A 4EIGA 4G8ZX 4DDRA 2QK8A 5HUIA 1MVSA 4M7UA 1RX2A 3DGAA 1DREA 1DHFA 2O7PA 1DIUA 2C2TA 3NZ9X 3JWCA 5HI6A 3TQ9A 5JG0X 5DXVA 3NXYA 3FQOA 3DL5A 3FS6A 4EILA 1RB2A 1IA1A 4PTJA 3SR5X 1RA3A 3EEKA 3ZPCA 5HQYA 1DR5A 1VDRA 3F0QX 4DFRA 1BOZA 3NZBX 4KM2A 3ROAA 4RGCA 1JOLA 1IA2A 3IROA 3QL0A 4PSTA 1DR1A 1RX7A 3NU0A 4KY4A 4KYAA 1J3IA 4P3RA 4M6KA 2DHFA 4KFJA 4H97A 3EIGA 4DPHA 1RX6A 3UM8A 4I1NA 3QFXA 4NX7A 1LY4A 3F8ZA 3FRBX 2ANQA 1U71A 2G6VA 4XT8A 3NXVA 4EJ1A 2DRCA 2HM9A 2HXVA 1DR7A 3R33A 4M2XA 3JVXA 1RX4A 4KBNA 3IX9A 5HSUA 1KMVA 3I8AX 4ELEA 4X5JA 2XW7A 1S3UA 3QLRA 4PDJA 4ELBA 3HJ3A 5EAJA 3UM6A 3VCOA 1RG7A 4X5HA 3SA2A 5E8QA 5DFRA 4PTHA 2FZHA 3M08A 2OBCA 4QI9A 5HVBA 3S3VA 3NZCX 4QJZD 5HT4A 1IA4A 3IA4A 2BLAA 3N0HA 4XT7A 4QLEA 2D0KA 2FZJA 3S9UA 4XE6X 3F0SX 5FDAA 5U27A 4ELGA 3CSEA 3NRRA 4CD2A 4KM0A 3SRQX 3KGYA 3CLBA 1OHKA 1LUDA 4M6JA 3F0BX 4ELFA 1DR4A 4P68A 4H96A 3NXXA 4DPDA 1DRAA 3QYOA 4FHBA 2BL9A 1DLSA 1AOEA 3GHWA 4KY8A 1S3YA 1E26A 5HSRA 1LY3A 1M78A 1DR2A 4TU5X 4XT5A 1DRFA 3JSUA 3FL9A 3RG9A 3NZAX 1RA9A 3SRWX 4HA9A 1RX9A 4KEBA 1AO8A 4P66A 4XT4A 4FGHA 2P4GA 3QLWA 3KFYA 3FY8X 3SH2A 4KJLA 3SRUX 3OCHA 4OR7A 1CZ3A
chains in the Genus database with same CATH superfamily
4XRBA 3M09A 4X5GA 3EX8A 3SQYX 3FQZA 1RB3A 3QG2A 3FQ0A 4XECX 3FL8A 1RF7A 3F0UX 1OHJA 3SA1A 1DISA 4IXED 3K2HA 3KJSA 4HA7A 4M7VA 1S3VA 4FGGA 1DRBA 1PD8A 5U26A 3TQAA 3QLXA 2GD9A 5CC9A 2BLBA 2W3BA 1U72A 3QLYA 3RO9A 1DRHA 2W3VA 4Q0EA 1PD9A 3UM5A 1DYIA 3DAUA 3K74A 4IXFX 2OIPA 3TQBA 4X5IA 4XT6A 1M7AA 2CD2A 4PSSA 1DHJA 1SEJA 1VJ3A 4HOEA 4KAKA 4QLGA 3FYVX 1DHIA 1DDSA 3FQFA 3JWFA 3GHVA 4KL9A 3KY8A 4KJJA 1J3KA 1YHOA 3EELA 4LAEX 3NTZA 4NX6A 1D1GA 3QGTA 4OSGA 3Q1HA 1DR6A 4KLXA 1TDRA 1J3JA 3L3RA 3D80A 3NXOA 5ECCA 3F0VX 3EEMA 3DG8A 4QLFA 3DL6A 1JUVA 3JWKA 3JWMA 1RC4A 3NZDA 3IA5A 3F8YA 3GYFA 5JA3A 3FYWX 1DR3A 1AI9A 3FREX 1DG5A 1DLRA 5HT5A 5CCCA 1RX8A 1IA3A 1HFPA 2KGKA 3IRNA 2W3MA 1ZDRA 3FRFX 2W9GA 2W3AA 1HFRA 4PSYA 1RA2A 2W9TA 1MVTA 1RA8A 1KLKA 4M6LA 5HF2X 1DG7A 2ITHA 2INQA 2W9SA 4DP3A 3EEJA 4KJKA 1S3WA 3QLSA 1DYHA 4LEKX 2ANOA 2FZIA 1CD2A 4X5FA 3QYLA 2W3WA 4QHVA 4KNEA 4GH8A 4I13A 5HF0X 3HBBA 4ELHA 3K47A 4HOFA 4IXGX 4HOGA 3FY9X 2D5NA 3NZ6X 1DYRA 1RA1A 2W9HA 3FQVA 1DG8A 4H95A 4Q6AA 3GHCA 2B3ZA 3GI2A 1RD7A 1QZFA 4G95A 2LF1A 3JW3A 4LAHX 1RE7A 4LAGX 3QLZA 3ZPGA 2ZZAA 1KMSA 3INVA 3DRCA 2BLCA 8DFRA 3F0XX 3E0BA 4EIZA 5HVEA 3LG4A 6DFRA 3FRDX 1DDRA 3QL3A 4KD7A 3SRSX 2AZNA 5HQZA 3NXTA 3TD8A 4QJCA 3OAFA 3SGYA 3JTWA 4H98A 4ECKA 3K45A 1RX3A 1U70A 3CD2A 3DFRA 4Q67A 3S7AA 1M79A 1RH3A 3KJRA 1DYJA 4G3MA 1DF7A 1HFQA 1DAJA 5ECXA 3DATA 2H2QA 1PDBA 4P3QA 3SAIA 3IRMA 4Q0DA 3FRAX 1JOMA 5HPBA 2CIGA 3D84X 7DFRA 3JW5A 3SRRX 1RX5A 3F91A 3I3RA 1BZFA 3CL9A 1RX1A 2HQPA 2JYBA 2C2SA 3FQCA 2L28A 3NXRA 3TQ8A 4EIGA 4G8ZX 4DDRA 2QK8A 5HUIA 1MVSA 4M7UA 1RX2A 3DGAA 1DREA 1DHFA 2O7PA 1DIUA 2C2TA 3NZ9X 3JWCA 5HI6A 3TQ9A 5JG0X 5DXVA 3NXYA 3FQOA 3DL5A 3FS6A 4EILA 1RB2A 1IA1A 4PTJA 3SR5X 1RA3A 3EEKA 3ZPCA 5HQYA 1DR5A 1VDRA 3F0QX 4DFRA 1BOZA 3NZBX 4KM2A 3ROAA 4RGCA 1JOLA 1IA2A 3IROA 3QL0A 4PSTA 1DR1A 1RX7A 3NU0A 4KY4A 4KYAA 1J3IA 4P3RA 4M6KA 2DHFA 4KFJA 4H97A 3EIGA 4DPHA 1RX6A 3UM8A 4I1NA 3QFXA 4NX7A 1LY4A 3F8ZA 3FRBX 2ANQA 1U71A 2G6VA 4XT8A 3NXVA 4EJ1A 2DRCA 2HM9A 2HXVA 1DR7A 3R33A 4M2XA 3JVXA 1RX4A 4KBNA 3IX9A 5HSUA 1KMVA 3I8AX 4ELEA 4X5JA 2XW7A 1S3UA 3QLRA 4PDJA 4ELBA 3HJ3A 5EAJA 3UM6A 3VCOA 1RG7A 4X5HA 3SA2A 5E8QA 5DFRA 4PTHA 2FZHA 3M08A 2OBCA 4QI9A 5HVBA 3S3VA 3NZCX 4QJZD 5HT4A 1IA4A 3IA4A 2BLAA 3N0HA 4XT7A 4QLEA 2D0KA 2FZJA 3S9UA 4XE6X 3F0SX 5FDAA 5U27A 4ELGA 3CSEA 3NRRA 4CD2A 4KM0A 3SRQX 3KGYA 3CLBA 1OHKA 1LUDA 4M6JA 3F0BX 4ELFA 1DR4A 4P68A 4H96A 3NXXA 4DPDA 1DRAA 3QYOA 4FHBA 2BL9A 1DLSA 1AOEA 3GHWA 4KY8A 1S3YA 1E26A 5HSRA 1LY3A 1M78A 1DR2A 4TU5X 4XT5A 1DRFA 3JSUA 3FL9A 3RG9A 3NZAX 1RA9A 3SRWX 4HA9A 1RX9A 4KEBA 1AO8A 4P66A 4XT4A 4FGHA 2P4GA 3QLWA 3KFYA 3FY8X 3SH2A 4KJLA 3SRUX 3OCHA 4OR7A 1CZ3A
chains in the Genus database with same CATH topology
4XRBA 3M09A 4X5GA 3EX8A 3SQYX 3FQZA 1RB3A 3QG2A 3FQ0A 4XECX 3FL8A 1RF7A 3F0UX 1OHJA 3SA1A 1DISA 4IXED 3K2HA 3KJSA 4HA7A 4M7VA 1S3VA 4FGGA 1DRBA 1PD8A 5U26A 3TQAA 3QLXA 2GD9A 5CC9A 2BLBA 2W3BA 1U72A 3QLYA 3RO9A 1DRHA 2W3VA 4Q0EA 1PD9A 3UM5A 1DYIA 3DAUA 3K74A 4IXFX 2OIPA 3TQBA 4X5IA 4XT6A 1M7AA 2CD2A 4PSSA 1DHJA 1SEJA 1VJ3A 4HOEA 4KAKA 4QLGA 3FYVX 1DHIA 1DDSA 3FQFA 3JWFA 3GHVA 4KL9A 3KY8A 4KJJA 1J3KA 1YHOA 3EELA 4LAEX 3NTZA 4NX6A 1D1GA 3QGTA 4OSGA 3Q1HA 1DR6A 4KLXA 1TDRA 1J3JA 3L3RA 3D80A 3NXOA 5ECCA 3F0VX 3EEMA 3DG8A 4QLFA 3DL6A 1JUVA 3JWKA 3JWMA 1RC4A 3NZDA 3IA5A 3F8YA 3GYFA 5JA3A 3FYWX 1DR3A 1AI9A 3FREX 1DG5A 1DLRA 5HT5A 5CCCA 1RX8A 1IA3A 1HFPA 2KGKA 3IRNA 2W3MA 1ZDRA 3FRFX 2W9GA 2W3AA 1HFRA 4PSYA 1RA2A 2W9TA 1MVTA 1RA8A 1KLKA 4M6LA 5HF2X 1DG7A 2ITHA 2INQA 2W9SA 4DP3A 3EEJA 4KJKA 1S3WA 3QLSA 1DYHA 4LEKX 2ANOA 2FZIA 1CD2A 4X5FA 3QYLA 2W3WA 4QHVA 4KNEA 4GH8A 4I13A 5HF0X 3HBBA 4ELHA 3K47A 4HOFA 4IXGX 4HOGA 3FY9X 2D5NA 3NZ6X 1DYRA 1RA1A 2W9HA 3FQVA 1DG8A 4H95A 4Q6AA 3GHCA 2B3ZA 3GI2A 1RD7A 1QZFA 4G95A 2LF1A 3JW3A 4LAHX 1RE7A 4LAGX 3QLZA 3ZPGA 2ZZAA 1KMSA 3INVA 3DRCA 2BLCA 8DFRA 3F0XX 3E0BA 4EIZA 5HVEA 3LG4A 6DFRA 3FRDX 1DDRA 3QL3A 4KD7A 3SRSX 2AZNA 5HQZA 3NXTA 3TD8A 4QJCA 3OAFA 3SGYA 3JTWA 4H98A 4ECKA 3K45A 1RX3A 1U70A 3CD2A 3DFRA 4Q67A 3S7AA 1M79A 1RH3A 3KJRA 1DYJA 4G3MA 1DF7A 1HFQA 1DAJA 5ECXA 3DATA 2H2QA 1PDBA 4P3QA 3SAIA 3IRMA 4Q0DA 3FRAX 1JOMA 5HPBA 2CIGA 3D84X 7DFRA 3JW5A 3SRRX 1RX5A 3F91A 3I3RA 1BZFA 3CL9A 1RX1A 2HQPA 2JYBA 2C2SA 3FQCA 2L28A 3NXRA 3TQ8A 4EIGA 4G8ZX 4DDRA 2QK8A 5HUIA 1MVSA 4M7UA 1RX2A 3DGAA 1DREA 1DHFA 2O7PA 1DIUA 2C2TA 3NZ9X 3JWCA 5HI6A 3TQ9A 5JG0X 5DXVA 3NXYA 3FQOA 3DL5A 3FS6A 4EILA 1RB2A 1IA1A 4PTJA 3SR5X 1RA3A 3EEKA 3ZPCA 5HQYA 1DR5A 1VDRA 3F0QX 4DFRA 1BOZA 3NZBX 4KM2A 3ROAA 4RGCA 1JOLA 1IA2A 3IROA 3QL0A 4PSTA 1DR1A 1RX7A 3NU0A 4KY4A 4KYAA 1J3IA 4P3RA 4M6KA 2DHFA 4KFJA 4H97A 3EIGA 4DPHA 1RX6A 3UM8A 4I1NA 3QFXA 4NX7A 1LY4A 3F8ZA 3FRBX 2ANQA 1U71A 2G6VA 4XT8A 3NXVA 4EJ1A 2DRCA 2HM9A 2HXVA 1DR7A 3R33A 4M2XA 3JVXA 1RX4A 4KBNA 3IX9A 5HSUA 1KMVA 3I8AX 4ELEA 4X5JA 2XW7A 1S3UA 3QLRA 4PDJA 4ELBA 3HJ3A 5EAJA 3UM6A 3VCOA 1RG7A 4X5HA 3SA2A 5E8QA 5DFRA 4PTHA 2FZHA 3M08A 2OBCA 4QI9A 5HVBA 3S3VA 3NZCX 4QJZD 5HT4A 1IA4A 3IA4A 2BLAA 3N0HA 4XT7A 4QLEA 2D0KA 2FZJA 3S9UA 4XE6X 3F0SX 5FDAA 5U27A 4ELGA 3CSEA 3NRRA 4CD2A 4KM0A 3SRQX 3KGYA 3CLBA 1OHKA 1LUDA 4M6JA 3F0BX 4ELFA 1DR4A 4P68A 4H96A 3NXXA 4DPDA 1DRAA 3QYOA 4FHBA 2BL9A 1DLSA 1AOEA 3GHWA 4KY8A 1S3YA 1E26A 5HSRA 1LY3A 1M78A 1DR2A 4TU5X 4XT5A 1DRFA 3JSUA 3FL9A 3RG9A 3NZAX 1RA9A 3SRWX 4HA9A 1RX9A 4KEBA 1AO8A 4P66A 4XT4A 4FGHA 2P4GA 3QLWA 3KFYA 3FY8X 3SH2A 4KJLA 3SRUX 3OCHA 4OR7A 1CZ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XRB A;  3M09 A;  4X5G A;  3EX8 A;  3SQY X;  3FQZ A;  1RB3 A;  3QG2 A;  3FQ0 A;  4XEC X;  3FL8 A;  1RF7 A;  3F0U X;  1OHJ A;  3SA1 A;  1DIS A;  4IXE D;  3K2H A;  3KJS A;  4HA7 A;  4M7V A;  1S3V A;  4FGG A;  1DRB A;  1PD8 A;  5U26 A;  3TQA A;  3QLX A;  2GD9 A;  5CC9 A;  2BLB A;  2W3B A;  1U72 A;  3QLY A;  3RO9 A;  1DRH A;  2W3V A;  4Q0E A;  1PD9 A;  3UM5 A;  1DYI A;  3DAU A;  3K74 A;  4IXF X;  2OIP A;  3TQB A;  4X5I A;  4XT6 A;  1M7A A;  2CD2 A;  4PSS A;  1DHJ A;  1SEJ A;  1VJ3 A;  4HOE A;  4KAK A;  4QLG A;  3FYV X;  1DHI A;  1DDS A;  3FQF A;  3JWF A;  3GHV A;  4KL9 A;  3KY8 A;  4KJJ A;  1J3K A;  1YHO A;  3EEL A;  4LAE X;  3NTZ A;  4NX6 A;  1D1G A;  3QGT A;  4OSG A;  3Q1H A;  1DR6 A;  4KLX A;  1TDR A;  1J3J A;  3L3R A;  3D80 A;  3NXO A;  5ECC A;  3F0V X;  3EEM A;  3DG8 A;  4QLF A;  3DL6 A;  1JUV A;  3JWK A;  3JWM A;  1RC4 A;  3NZD A;  3IA5 A;  3F8Y A;  3GYF A;  5JA3 A;  3FYW X;  1DR3 A;  1AI9 A;  3FRE X;  1DG5 A;  1DLR A;  5HT5 A;  5CCC A;  1RX8 A;  1IA3 A;  1HFP A;  2KGK A;  3IRN A;  2W3M A;  1ZDR A;  3FRF X;  2W9G A;  2W3A A;  1HFR A;  4PSY A;  1RA2 A;  2W9T A;  1MVT A;  1RA8 A;  1KLK A;  4M6L A;  5HF2 X;  1DG7 A;  2ITH A;  2INQ A;  2W9S A;  4DP3 A;  3EEJ A;  4KJK A;  1S3W A;  3QLS A;  1DYH A;  4LEK X;  2ANO A;  2FZI A;  1CD2 A;  4X5F A;  3QYL A;  2W3W A;  4QHV A;  4KNE A;  4GH8 A;  4I13 A;  5HF0 X;  3HBB A;  4ELH A;  3K47 A;  4HOF A;  4IXG X;  4HOG A;  3FY9 X;  2D5N A;  3NZ6 X;  1DYR A;  1RA1 A;  2W9H A;  3FQV A;  1DG8 A;  4H95 A;  4Q6A A;  3GHC A;  2B3Z A;  3GI2 A;  1RD7 A;  1QZF A;  4G95 A;  2LF1 A;  3JW3 A;  4LAH X;  1RE7 A;  4LAG X;  3QLZ A;  3ZPG A;  2ZZA A;  1KMS A;  3INV A;  3DRC A;  2BLC A;  8DFR A;  3F0X X;  3E0B A;  4EIZ A;  5HVE A;  3LG4 A;  6DFR A;  3FRD X;  1DDR A;  3QL3 A;  4KD7 A;  3SRS X;  2AZN A;  5HQZ A;  3NXT A;  3TD8 A;  4QJC A;  3OAF A;  3SGY A;  3JTW A;  4H98 A;  4ECK A;  3K45 A;  1RX3 A;  1U70 A;  3CD2 A;  3DFR A;  4Q67 A;  3S7A A;  1M79 A;  1RH3 A;  3KJR A;  1DYJ A;  4G3M A;  1DF7 A;  1HFQ A;  1DAJ A;  5ECX A;  3DAT A;  2H2Q A;  1PDB A;  4P3Q A;  3SAI A;  3IRM A;  4Q0D A;  3FRA X;  1JOM A;  5HPB A;  2CIG A;  3D84 X;  7DFR A;  3JW5 A;  3SRR X;  1RX5 A;  3F91 A;  3I3R A;  1BZF A;  3CL9 A;  1RX1 A;  2HQP A;  2JYB A;  2C2S A;  3FQC A;  2L28 A;  3NXR A;  3TQ8 A;  4EIG A;  4G8Z X;  4DDR A;  2QK8 A;  5HUI A;  1MVS A;  4M7U A;  1RX2 A;  3DGA A;  1DRE A;  1DHF A;  2O7P A;  1DIU A;  2C2T A;  3NZ9 X;  3JWC A;  5HI6 A;  3TQ9 A;  5JG0 X;  5DXV A;  3NXY A;  3FQO A;  3DL5 A;  3FS6 A;  4EIL A;  1RB2 A;  1IA1 A;  4PTJ A;  3SR5 X;  1RA3 A;  3EEK A;  3ZPC A;  5HQY A;  1DR5 A;  1VDR A;  3F0Q X;  4DFR A;  1BOZ A;  3NZB X;  4KM2 A;  3ROA A;  4RGC A;  1JOL A;  1IA2 A;  3IRO A;  3QL0 A;  4PST A;  1DR1 A;  1RX7 A;  3NU0 A;  4KY4 A;  4KYA A;  1J3I A;  4P3R A;  4M6K A;  2DHF A;  4KFJ A;  4H97 A;  3EIG A;  4DPH A;  1RX6 A;  3UM8 A;  4I1N A;  3QFX A;  4NX7 A;  1LY4 A;  3F8Z A;  3FRB X;  2ANQ A;  1U71 A;  2G6V A;  4XT8 A;  3NXV A;  4EJ1 A;  2DRC A;  2HM9 A;  2HXV A;  1DR7 A;  3R33 A;  4M2X A;  3JVX A;  1RX4 A;  4KBN A;  3IX9 A;  5HSU A;  1KMV A;  3I8A X;  4ELE A;  4X5J A;  2XW7 A;  1S3U A;  3QLR A;  4PDJ A;  4ELB A;  3HJ3 A;  5EAJ A;  3UM6 A;  3VCO A;  1RG7 A;  4X5H A;  3SA2 A;  5E8Q A;  5DFR A;  4PTH A;  2FZH A;  3M08 A;  2OBC A;  4QI9 A;  5HVB A;  3S3V A;  3NZC X;  4QJZ D;  5HT4 A;  1IA4 A;  3IA4 A;  2BLA A;  3N0H A;  4XT7 A;  4QLE A;  2D0K A;  2FZJ A;  3S9U A;  4XE6 X;  3F0S X;  5FDA A;  5U27 A;  4ELG A;  3CSE A;  3NRR A;  4CD2 A;  4KM0 A;  3SRQ X;  3KGY A;  3CLB A;  1OHK A;  1LUD A;  4M6J A;  3F0B X;  4ELF A;  1DR4 A;  4P68 A;  4H96 A;  3NXX A;  4DPD A;  1DRA A;  3QYO A;  4FHB A;  2BL9 A;  1DLS A;  1AOE A;  3GHW A;  4KY8 A;  1S3Y A;  1E26 A;  5HSR A;  1LY3 A;  1M78 A;  1DR2 A;  4TU5 X;  4XT5 A;  1DRF A;  3JSU A;  3FL9 A;  3RG9 A;  3NZA X;  1RA9 A;  3SRW X;  4HA9 A;  1RX9 A;  4KEB A;  1AO8 A;  4P66 A;  4XT4 A;  4FGH A;  2P4G A;  3QLW A;  3KFY A;  3FY8 X;  3SH2 A;  4KJL A;  3SRU X;  3OCH A;  4OR7 A;  1CZ3 A; 
#chains in the Genus database with same CATH topology
 4XRB A;  3M09 A;  4X5G A;  3EX8 A;  3SQY X;  3FQZ A;  1RB3 A;  3QG2 A;  3FQ0 A;  4XEC X;  3FL8 A;  1RF7 A;  3F0U X;  1OHJ A;  3SA1 A;  1DIS A;  4IXE D;  3K2H A;  3KJS A;  4HA7 A;  4M7V A;  1S3V A;  4FGG A;  1DRB A;  1PD8 A;  5U26 A;  3TQA A;  3QLX A;  2GD9 A;  5CC9 A;  2BLB A;  2W3B A;  1U72 A;  3QLY A;  3RO9 A;  1DRH A;  2W3V A;  4Q0E A;  1PD9 A;  3UM5 A;  1DYI A;  3DAU A;  3K74 A;  4IXF X;  2OIP A;  3TQB A;  4X5I A;  4XT6 A;  1M7A A;  2CD2 A;  4PSS A;  1DHJ A;  1SEJ A;  1VJ3 A;  4HOE A;  4KAK A;  4QLG A;  3FYV X;  1DHI A;  1DDS A;  3FQF A;  3JWF A;  3GHV A;  4KL9 A;  3KY8 A;  4KJJ A;  1J3K A;  1YHO A;  3EEL A;  4LAE X;  3NTZ A;  4NX6 A;  1D1G A;  3QGT A;  4OSG A;  3Q1H A;  1DR6 A;  4KLX A;  1TDR A;  1J3J A;  3L3R A;  3D80 A;  3NXO A;  5ECC A;  3F0V X;  3EEM A;  3DG8 A;  4QLF A;  3DL6 A;  1JUV A;  3JWK A;  3JWM A;  1RC4 A;  3NZD A;  3IA5 A;  3F8Y A;  3GYF A;  5JA3 A;  3FYW X;  1DR3 A;  1AI9 A;  3FRE X;  1DG5 A;  1DLR A;  5HT5 A;  5CCC A;  1RX8 A;  1IA3 A;  1HFP A;  2KGK A;  3IRN A;  2W3M A;  1ZDR A;  3FRF X;  2W9G A;  2W3A A;  1HFR A;  4PSY A;  1RA2 A;  2W9T A;  1MVT A;  1RA8 A;  1KLK A;  4M6L A;  5HF2 X;  1DG7 A;  2ITH A;  2INQ A;  2W9S A;  4DP3 A;  3EEJ A;  4KJK A;  1S3W A;  3QLS A;  1DYH A;  4LEK X;  2ANO A;  2FZI A;  1CD2 A;  4X5F A;  3QYL A;  2W3W A;  4QHV A;  4KNE A;  4GH8 A;  4I13 A;  5HF0 X;  3HBB A;  4ELH A;  3K47 A;  4HOF A;  4IXG X;  4HOG A;  3FY9 X;  2D5N A;  3NZ6 X;  1DYR A;  1RA1 A;  2W9H A;  3FQV A;  1DG8 A;  4H95 A;  4Q6A A;  3GHC A;  2B3Z A;  3GI2 A;  1RD7 A;  1QZF A;  4G95 A;  2LF1 A;  3JW3 A;  4LAH X;  1RE7 A;  4LAG X;  3QLZ A;  3ZPG A;  2ZZA A;  1KMS A;  3INV A;  3DRC A;  2BLC A;  8DFR A;  3F0X X;  3E0B A;  4EIZ A;  5HVE A;  3LG4 A;  6DFR A;  3FRD X;  1DDR A;  3QL3 A;  4KD7 A;  3SRS X;  2AZN A;  5HQZ A;  3NXT A;  3TD8 A;  4QJC A;  3OAF A;  3SGY A;  3JTW A;  4H98 A;  4ECK A;  3K45 A;  1RX3 A;  1U70 A;  3CD2 A;  3DFR A;  4Q67 A;  3S7A A;  1M79 A;  1RH3 A;  3KJR A;  1DYJ A;  4G3M A;  1DF7 A;  1HFQ A;  1DAJ A;  5ECX A;  3DAT A;  2H2Q A;  1PDB A;  4P3Q A;  3SAI A;  3IRM A;  4Q0D A;  3FRA X;  1JOM A;  5HPB A;  2CIG A;  3D84 X;  7DFR A;  3JW5 A;  3SRR X;  1RX5 A;  3F91 A;  3I3R A;  1BZF A;  3CL9 A;  1RX1 A;  2HQP A;  2JYB A;  2C2S A;  3FQC A;  2L28 A;  3NXR A;  3TQ8 A;  4EIG A;  4G8Z X;  4DDR A;  2QK8 A;  5HUI A;  1MVS A;  4M7U A;  1RX2 A;  3DGA A;  1DRE A;  1DHF A;  2O7P A;  1DIU A;  2C2T A;  3NZ9 X;  3JWC A;  5HI6 A;  3TQ9 A;  5JG0 X;  5DXV A;  3NXY A;  3FQO A;  3DL5 A;  3FS6 A;  4EIL A;  1RB2 A;  1IA1 A;  4PTJ A;  3SR5 X;  1RA3 A;  3EEK A;  3ZPC A;  5HQY A;  1DR5 A;  1VDR A;  3F0Q X;  4DFR A;  1BOZ A;  3NZB X;  4KM2 A;  3ROA A;  4RGC A;  1JOL A;  1IA2 A;  3IRO A;  3QL0 A;  4PST A;  1DR1 A;  1RX7 A;  3NU0 A;  4KY4 A;  4KYA A;  1J3I A;  4P3R A;  4M6K A;  2DHF A;  4KFJ A;  4H97 A;  3EIG A;  4DPH A;  1RX6 A;  3UM8 A;  4I1N A;  3QFX A;  4NX7 A;  1LY4 A;  3F8Z A;  3FRB X;  2ANQ A;  1U71 A;  2G6V A;  4XT8 A;  3NXV A;  4EJ1 A;  2DRC A;  2HM9 A;  2HXV A;  1DR7 A;  3R33 A;  4M2X A;  3JVX A;  1RX4 A;  4KBN A;  3IX9 A;  5HSU A;  1KMV A;  3I8A X;  4ELE A;  4X5J A;  2XW7 A;  1S3U A;  3QLR A;  4PDJ A;  4ELB A;  3HJ3 A;  5EAJ A;  3UM6 A;  3VCO A;  1RG7 A;  4X5H A;  3SA2 A;  5E8Q A;  5DFR A;  4PTH A;  2FZH A;  3M08 A;  2OBC A;  4QI9 A;  5HVB A;  3S3V A;  3NZC X;  4QJZ D;  5HT4 A;  1IA4 A;  3IA4 A;  2BLA A;  3N0H A;  4XT7 A;  4QLE A;  2D0K A;  2FZJ A;  3S9U A;  4XE6 X;  3F0S X;  5FDA A;  5U27 A;  4ELG A;  3CSE A;  3NRR A;  4CD2 A;  4KM0 A;  3SRQ X;  3KGY A;  3CLB A;  1OHK A;  1LUD A;  4M6J A;  3F0B X;  4ELF A;  1DR4 A;  4P68 A;  4H96 A;  3NXX A;  4DPD A;  1DRA A;  3QYO A;  4FHB A;  2BL9 A;  1DLS A;  1AOE A;  3GHW A;  4KY8 A;  1S3Y A;  1E26 A;  5HSR A;  1LY3 A;  1M78 A;  1DR2 A;  4TU5 X;  4XT5 A;  1DRF A;  3JSU A;  3FL9 A;  3RG9 A;  3NZA X;  1RA9 A;  3SRW X;  4HA9 A;  1RX9 A;  4KEB A;  1AO8 A;  4P66 A;  4XT4 A;  4FGH A;  2P4G A;  3QLW A;  3KFY A;  3FY8 X;  3SH2 A;  4KJL A;  3SRU X;  3OCH A;  4OR7 A;  1CZ3 A; 
#chains in the Genus database with same CATH homology
 4XRB A;  3M09 A;  4X5G A;  3EX8 A;  3SQY X;  3FQZ A;  1RB3 A;  3QG2 A;  3FQ0 A;  4XEC X;  3FL8 A;  1RF7 A;  3F0U X;  1OHJ A;  3SA1 A;  1DIS A;  4IXE D;  3K2H A;  3KJS A;  4HA7 A;  4M7V A;  1S3V A;  4FGG A;  1DRB A;  1PD8 A;  5U26 A;  3TQA A;  3QLX A;  2GD9 A;  5CC9 A;  2BLB A;  2W3B A;  1U72 A;  3QLY A;  3RO9 A;  1DRH A;  2W3V A;  4Q0E A;  1PD9 A;  3UM5 A;  1DYI A;  3DAU A;  3K74 A;  4IXF X;  2OIP A;  3TQB A;  4X5I A;  4XT6 A;  1M7A A;  2CD2 A;  4PSS A;  1DHJ A;  1SEJ A;  1VJ3 A;  4HOE A;  4KAK A;  4QLG A;  3FYV X;  1DHI A;  1DDS A;  3FQF A;  3JWF A;  3GHV A;  4KL9 A;  3KY8 A;  4KJJ A;  1J3K A;  1YHO A;  3EEL A;  4LAE X;  3NTZ A;  4NX6 A;  1D1G A;  3QGT A;  4OSG A;  3Q1H A;  1DR6 A;  4KLX A;  1TDR A;  1J3J A;  3L3R A;  3D80 A;  3NXO A;  5ECC A;  3F0V X;  3EEM A;  3DG8 A;  4QLF A;  3DL6 A;  1JUV A;  3JWK A;  3JWM A;  1RC4 A;  3NZD A;  3IA5 A;  3F8Y A;  3GYF A;  5JA3 A;  3FYW X;  1DR3 A;  1AI9 A;  3FRE X;  1DG5 A;  1DLR A;  5HT5 A;  5CCC A;  1RX8 A;  1IA3 A;  1HFP A;  2KGK A;  3IRN A;  2W3M A;  1ZDR A;  3FRF X;  2W9G A;  2W3A A;  1HFR A;  4PSY A;  1RA2 A;  2W9T A;  1MVT A;  1RA8 A;  1KLK A;  4M6L A;  5HF2 X;  1DG7 A;  2ITH A;  2INQ A;  2W9S A;  4DP3 A;  3EEJ A;  4KJK A;  1S3W A;  3QLS A;  1DYH A;  4LEK X;  2ANO A;  2FZI A;  1CD2 A;  4X5F A;  3QYL A;  2W3W A;  4QHV A;  4KNE A;  4GH8 A;  4I13 A;  5HF0 X;  3HBB A;  4ELH A;  3K47 A;  4HOF A;  4IXG X;  4HOG A;  3FY9 X;  2D5N A;  3NZ6 X;  1DYR A;  1RA1 A;  2W9H A;  3FQV A;  1DG8 A;  4H95 A;  4Q6A A;  3GHC A;  2B3Z A;  3GI2 A;  1RD7 A;  1QZF A;  4G95 A;  2LF1 A;  3JW3 A;  4LAH X;  1RE7 A;  4LAG X;  3QLZ A;  3ZPG A;  2ZZA A;  1KMS A;  3INV A;  3DRC A;  2BLC A;  8DFR A;  3F0X X;  3E0B A;  4EIZ A;  5HVE A;  3LG4 A;  6DFR A;  3FRD X;  1DDR A;  3QL3 A;  4KD7 A;  3SRS X;  2AZN A;  5HQZ A;  3NXT A;  3TD8 A;  4QJC A;  3OAF A;  3SGY A;  3JTW A;  4H98 A;  4ECK A;  3K45 A;  1RX3 A;  1U70 A;  3CD2 A;  3DFR A;  4Q67 A;  3S7A A;  1M79 A;  1RH3 A;  3KJR A;  1DYJ A;  4G3M A;  1DF7 A;  1HFQ A;  1DAJ A;  5ECX A;  3DAT A;  2H2Q A;  1PDB A;  4P3Q A;  3SAI A;  3IRM A;  4Q0D A;  3FRA X;  1JOM A;  5HPB A;  2CIG A;  3D84 X;  7DFR A;  3JW5 A;  3SRR X;  1RX5 A;  3F91 A;  3I3R A;  1BZF A;  3CL9 A;  1RX1 A;  2HQP A;  2JYB A;  2C2S A;  3FQC A;  2L28 A;  3NXR A;  3TQ8 A;  4EIG A;  4G8Z X;  4DDR A;  2QK8 A;  5HUI A;  1MVS A;  4M7U A;  1RX2 A;  3DGA A;  1DRE A;  1DHF A;  2O7P A;  1DIU A;  2C2T A;  3NZ9 X;  3JWC A;  5HI6 A;  3TQ9 A;  5JG0 X;  5DXV A;  3NXY A;  3FQO A;  3DL5 A;  3FS6 A;  4EIL A;  1RB2 A;  1IA1 A;  4PTJ A;  3SR5 X;  1RA3 A;  3EEK A;  3ZPC A;  5HQY A;  1DR5 A;  1VDR A;  3F0Q X;  4DFR A;  1BOZ A;  3NZB X;  4KM2 A;  3ROA A;  4RGC A;  1JOL A;  1IA2 A;  3IRO A;  3QL0 A;  4PST A;  1DR1 A;  1RX7 A;  3NU0 A;  4KY4 A;  4KYA A;  1J3I A;  4P3R A;  4M6K A;  2DHF A;  4KFJ A;  4H97 A;  3EIG A;  4DPH A;  1RX6 A;  3UM8 A;  4I1N A;  3QFX A;  4NX7 A;  1LY4 A;  3F8Z A;  3FRB X;  2ANQ A;  1U71 A;  2G6V A;  4XT8 A;  3NXV A;  4EJ1 A;  2DRC A;  2HM9 A;  2HXV A;  1DR7 A;  3R33 A;  4M2X A;  3JVX A;  1RX4 A;  4KBN A;  3IX9 A;  5HSU A;  1KMV A;  3I8A X;  4ELE A;  4X5J A;  2XW7 A;  1S3U A;  3QLR A;  4PDJ A;  4ELB A;  3HJ3 A;  5EAJ A;  3UM6 A;  3VCO A;  1RG7 A;  4X5H A;  3SA2 A;  5E8Q A;  5DFR A;  4PTH A;  2FZH A;  3M08 A;  2OBC A;  4QI9 A;  5HVB A;  3S3V A;  3NZC X;  4QJZ D;  5HT4 A;  1IA4 A;  3IA4 A;  2BLA A;  3N0H A;  4XT7 A;  4QLE A;  2D0K A;  2FZJ A;  3S9U A;  4XE6 X;  3F0S X;  5FDA A;  5U27 A;  4ELG A;  3CSE A;  3NRR A;  4CD2 A;  4KM0 A;  3SRQ X;  3KGY A;  3CLB A;  1OHK A;  1LUD A;  4M6J A;  3F0B X;  4ELF A;  1DR4 A;  4P68 A;  4H96 A;  3NXX A;  4DPD A;  1DRA A;  3QYO A;  4FHB A;  2BL9 A;  1DLS A;  1AOE A;  3GHW A;  4KY8 A;  1S3Y A;  1E26 A;  5HSR A;  1LY3 A;  1M78 A;  1DR2 A;  4TU5 X;  4XT5 A;  1DRF A;  3JSU A;  3FL9 A;  3RG9 A;  3NZA X;  1RA9 A;  3SRW X;  4HA9 A;  1RX9 A;  4KEB A;  1AO8 A;  4P66 A;  4XT4 A;  4FGH A;  2P4G A;  3QLW A;  3KFY A;  3FY8 X;  3SH2 A;  4KJL A;  3SRU X;  3OCH A;  4OR7 A;  1CZ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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