2W3WA

Mycobacterium avium dihydrofolate reductase complexed with nadph and a lipophilic antifolate selective for m. avium dhfr, 6-((2,5- diethoxyphenyl)aminomethyl)-2,4-diamino-5-methylpyrido(2,3-d) pyrimidine (sri-8686)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
164
structure length
164
Chain Sequence
RAEVGLVWAQSTSGVIGRGGDIPWSVPEDLTRFKEVTMGHTVIMGRRTWESLPAKVRPLPGRRNVVVSRRPDFVAEGARVAGSLEAALAYAGSDPAPWVIGGAQIYLLALPHATRCEVTEIEIDLRRDDDDALAPALDDSWVGETGEWLASRSGLRYRFHSYRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
rcsb
molecule tags Oxidoreductase
source organism Mycobacterium avium
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 48
structure length 164
sequence length 164
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 2w3wA00
4ELEA 2C2TA 4HOFA 5DFRA 1RG7A 1PD9A 5HVBA 2W9GA 4X5HA 3S3VA 2HXVA 1AO8A 2W3MA 3NXXA 4H96A 2W9TA 3F0UX 4Q6AA 1ZDRA 4QJCA 1DR7A 4M6JA 4P3RA 3VCOA 3M08A 4XT5A 4FGGA 3DG8A 3SQYX 3SRWX 3TQ8A 4ELHA 3EELA 3EX8A 4DFRA 2XW7A 2AZNA 3QLZA 1LUDA 1PDBA 4QLFA 4ELGA 1HFQA 1JOLA 3FQFA 5HVEA 4DPHA 3JW5A 3QL3A 4XE6X 3DGAA 3M09A 3NTZA 2FZIA 3GHWA 4EIGA 4HA7A 3F91A 4Q0EA 4TU5X 2CIGA 1IA2A 3S7AA 1DHFA 3NZ9X 3QLSA 2G6VA 4QHVA 4DDRA 4PDJA 3EIGA 4G3MA 1DYJA 4CD2A 3FQ0A 1DLRA 3SAIA 2BLAA 2OBCA 3EEKA 3E0BA 5U26A 4OR7A 3FREX 4X5GA 3FQOA 2GD9A 1DREA 1DG8A 1DHIA 3F8YA 3JVXA 3OCHA 1RB2A 3JWCA 3NXVA 4KD7A 2L28A 3JWKA 4KNEA 3TQAA 1U70A 4XRBA 1DR6A 1RB3A 3FQZA 3JW3A 3IA5A 5EAJA 3SH2A 1QZFA 3K2HA 1CZ3A 1RA3A 3OAFA 1VDRA 4PSSA 3CL9A 1RC4A 3K45A 3NZ6X 3FYVX 3QYOA 4QLEA 3S9UA 2D0KA 2W3WA 1OHJA 1SEJA 4NX6A 1DRFA 1M78A 3DL6A 2DHFA 4M7UA 3D84X 3Q1HA 4QLGA 4EIZA 4XT6A 1RX2A 1S3WA 4KEBA 1TDRA 4XT7A 4X5JA 4P68A 4PSTA 3KY8A 4GH8A 4KAKA 1RA9A 3DAUA 3NXOA 4M6LA 3UM6A 3QLWA 3KJSA 5HQZA 3INVA 1DR1A 1CD2A 1D1GA 4QJZD 1M79A 1OHKA 5JG0X 2W3AA 2LF1A 2O7PA 4EILA 4IXED 1RX8A 4FHBA 4KY8A 3CLBA 4P3QA 5HSUA 1RA8A 3QLRA 4KJKA 5HF0X 3SA1A 5HT4A 3IRNA 3QGTA 1U71A 2INQA 1DG7A 3DFRA 1DYHA 4G8ZX 1RX1A 4KM0A 1DDRA 2JYBA 4FGHA 3NZAX 4Q0DA 1LY4A 1DIUA 4PSYA 4ELBA 3FYWX 1DRBA 3IRMA 3SA2A 1AOEA 3DL5A 2HQPA 3F8ZA 3NXTA 1DRHA 1JUVA 1RX4A 3NRRA 5HQYA 4I13A 3NZDA 3QLYA 4KJJA 1KLKA 5ECCA 3I3RA 4QI9A 4HOGA 3K47A 1DRAA 3D80A 4KLXA 3L3RA 2HM9A 4LEKX 5U27A 2ITHA 5DXVA 3SR5X 3SRUX 4KY4A 1RX5A 1YHOA 3QG2A 4RGCA 4G95A 1DR5A 1RF7A 1DISA 3ZPCA 2H2QA 3UM5A 3QFXA 4KBNA 3GHCA 3NZCX 1RX3A 4DPDA 4KYAA 4XECX 3NU0A 3SRRX 3TQ9A 1HFPA 3GI2A 1BZFA 3NXYA 2W9SA 1MVSA 4M6KA 1MVTA 1DR3A 1S3UA 3FRFX 3SRQX 3LG4A 3KJRA 3RG9A 1S3YA 1DR2A 4KL9A 4OSGA 1HFRA 3NXRA 4PTHA 3JSUA 3I8AX 1DF7A 2ANOA 5FDAA 1AI9A 4H98A 4ECKA 3QL0A 3JWFA 4H95A 2W3BA 3N0HA 1LY3A 1J3JA 2BLBA 5CCCA 5HUIA 2FZHA 1DYIA 3TQBA 3JWMA 1DR4A 3JTWA 1DAJA 5JA3A 1U72A 4XT4A 1DYRA 1RH3A 7DFRA 4ELFA 4IXGX 2DRCA 4LAHX 3HJ3A 1IA3A 4I1NA 4IXFX 2ANQA 1KMSA 3F0XX 1RA1A 1RE7A 4H97A 3FQCA 3FL9A 4M7VA 4P66A 2QK8A 2D5NA 1RX6A 1DLSA 2FZJA 1IA1A 1KMVA 3DATA 3FS6A 3F0SX 3GHVA 3CSEA 1PD8A 4LAGX 3CD2A 4M2XA 5HI6A 4Q67A 1E26A 3QYLA 1VJ3A 1J3IA 1DHJA 3EEJA 2KGKA 3NZBX 3K74A 3ROAA 4KJLA 3HBBA 2BL9A 2P4GA 1S3VA 1RX7A 4LAEX 3EEMA 1DG5A 4KFJA 3FL8A 4HOEA 5E8QA 3ZPGA 4X5IA 2W3VA 3F0BX 3QLXA 2BLCA 5HSRA 1J3KA 6DFRA 2C2SA 3DRCA 3KGYA 3SRSX 1RA2A 2ZZAA 3SGYA 2OIPA 4PTJA 3FQVA 3FY8X 4EJ1A 1RD7A 3IX9A 3UM8A 3F0QX 3FRBX 2CD2A 3RO9A 2B3ZA 5HF2X 1JOMA 3F0VX 4NX7A 1RX9A 3IROA 3FY9X 5CC9A 4HA9A 3IA4A 3TD8A 8DFRA 3FRDX 4KM2A 3KFYA 1IA4A 3GYFA 4XT8A 1DDSA 4DP3A 1BOZA 4X5FA 5HPBA 5HT5A 1M7AA 3FRAX 5ECXA 2W9HA 3R33A
chains in the Genus database with same CATH superfamily
4ELEA 2C2TA 4HOFA 5DFRA 1RG7A 1PD9A 5HVBA 2W9GA 4X5HA 3S3VA 2HXVA 1AO8A 2W3MA 3NXXA 4H96A 2W9TA 3F0UX 4Q6AA 1ZDRA 4QJCA 1DR7A 4M6JA 4P3RA 3VCOA 3M08A 4XT5A 4FGGA 3DG8A 3SQYX 3SRWX 3TQ8A 4ELHA 3EELA 3EX8A 4DFRA 2XW7A 2AZNA 3QLZA 1LUDA 1PDBA 4QLFA 4ELGA 1HFQA 1JOLA 3FQFA 5HVEA 4DPHA 3JW5A 3QL3A 4XE6X 3DGAA 3M09A 3NTZA 2FZIA 3GHWA 4EIGA 4HA7A 3F91A 4Q0EA 4TU5X 2CIGA 1IA2A 3S7AA 1DHFA 3NZ9X 3QLSA 2G6VA 4QHVA 4DDRA 4PDJA 3EIGA 4G3MA 1DYJA 4CD2A 3FQ0A 1DLRA 3SAIA 2BLAA 2OBCA 3EEKA 3E0BA 5U26A 4OR7A 3FREX 4X5GA 3FQOA 2GD9A 1DREA 1DG8A 1DHIA 3F8YA 3JVXA 3OCHA 1RB2A 3JWCA 3NXVA 4KD7A 2L28A 3JWKA 4KNEA 3TQAA 1U70A 4XRBA 1DR6A 1RB3A 3FQZA 3JW3A 3IA5A 5EAJA 3SH2A 1QZFA 3K2HA 1CZ3A 1RA3A 3OAFA 1VDRA 4PSSA 3CL9A 1RC4A 3K45A 3NZ6X 3FYVX 3QYOA 4QLEA 3S9UA 2D0KA 2W3WA 1OHJA 1SEJA 4NX6A 1DRFA 1M78A 3DL6A 2DHFA 4M7UA 3D84X 3Q1HA 4QLGA 4EIZA 4XT6A 1RX2A 1S3WA 4KEBA 1TDRA 4XT7A 4X5JA 4P68A 4PSTA 3KY8A 4GH8A 4KAKA 1RA9A 3DAUA 3NXOA 4M6LA 3UM6A 3QLWA 3KJSA 5HQZA 3INVA 1DR1A 1CD2A 1D1GA 4QJZD 1M79A 1OHKA 5JG0X 2W3AA 2LF1A 2O7PA 4EILA 4IXED 1RX8A 4FHBA 4KY8A 3CLBA 4P3QA 5HSUA 1RA8A 3QLRA 4KJKA 5HF0X 3SA1A 5HT4A 3IRNA 3QGTA 1U71A 2INQA 1DG7A 3DFRA 1DYHA 4G8ZX 1RX1A 4KM0A 1DDRA 2JYBA 4FGHA 3NZAX 4Q0DA 1LY4A 1DIUA 4PSYA 4ELBA 3FYWX 1DRBA 3IRMA 3SA2A 1AOEA 3DL5A 2HQPA 3F8ZA 3NXTA 1DRHA 1JUVA 1RX4A 3NRRA 5HQYA 4I13A 3NZDA 3QLYA 4KJJA 1KLKA 5ECCA 3I3RA 4QI9A 4HOGA 3K47A 1DRAA 3D80A 4KLXA 3L3RA 2HM9A 4LEKX 5U27A 2ITHA 5DXVA 3SR5X 3SRUX 4KY4A 1RX5A 1YHOA 3QG2A 4RGCA 4G95A 1DR5A 1RF7A 1DISA 3ZPCA 2H2QA 3UM5A 3QFXA 4KBNA 3GHCA 3NZCX 1RX3A 4DPDA 4KYAA 4XECX 3NU0A 3SRRX 3TQ9A 1HFPA 3GI2A 1BZFA 3NXYA 2W9SA 1MVSA 4M6KA 1MVTA 1DR3A 1S3UA 3FRFX 3SRQX 3LG4A 3KJRA 3RG9A 1S3YA 1DR2A 4KL9A 4OSGA 1HFRA 3NXRA 4PTHA 3JSUA 3I8AX 1DF7A 2ANOA 5FDAA 1AI9A 4H98A 4ECKA 3QL0A 3JWFA 4H95A 2W3BA 3N0HA 1LY3A 1J3JA 2BLBA 5CCCA 5HUIA 2FZHA 1DYIA 3TQBA 3JWMA 1DR4A 3JTWA 1DAJA 5JA3A 1U72A 4XT4A 1DYRA 1RH3A 7DFRA 4ELFA 4IXGX 2DRCA 4LAHX 3HJ3A 1IA3A 4I1NA 4IXFX 2ANQA 1KMSA 3F0XX 1RA1A 1RE7A 4H97A 3FQCA 3FL9A 4M7VA 4P66A 2QK8A 2D5NA 1RX6A 1DLSA 2FZJA 1IA1A 1KMVA 3DATA 3FS6A 3F0SX 3GHVA 3CSEA 1PD8A 4LAGX 3CD2A 4M2XA 5HI6A 4Q67A 1E26A 3QYLA 1VJ3A 1J3IA 1DHJA 3EEJA 2KGKA 3NZBX 3K74A 3ROAA 4KJLA 3HBBA 2BL9A 2P4GA 1S3VA 1RX7A 4LAEX 3EEMA 1DG5A 4KFJA 3FL8A 4HOEA 5E8QA 3ZPGA 4X5IA 2W3VA 3F0BX 3QLXA 2BLCA 5HSRA 1J3KA 6DFRA 2C2SA 3DRCA 3KGYA 3SRSX 1RA2A 2ZZAA 3SGYA 2OIPA 4PTJA 3FQVA 3FY8X 4EJ1A 1RD7A 3IX9A 3UM8A 3F0QX 3FRBX 2CD2A 3RO9A 2B3ZA 5HF2X 1JOMA 3F0VX 4NX7A 1RX9A 3IROA 3FY9X 5CC9A 4HA9A 3IA4A 3TD8A 8DFRA 3FRDX 4KM2A 3KFYA 1IA4A 3GYFA 4XT8A 1DDSA 4DP3A 1BOZA 4X5FA 5HPBA 5HT5A 1M7AA 3FRAX 5ECXA 2W9HA 3R33A
chains in the Genus database with same CATH topology
4ELEA 2C2TA 4HOFA 5DFRA 1RG7A 1PD9A 5HVBA 2W9GA 4X5HA 3S3VA 2HXVA 1AO8A 2W3MA 3NXXA 4H96A 2W9TA 3F0UX 4Q6AA 1ZDRA 4QJCA 1DR7A 4M6JA 4P3RA 3VCOA 3M08A 4XT5A 4FGGA 3DG8A 3SQYX 3SRWX 3TQ8A 4ELHA 3EELA 3EX8A 4DFRA 2XW7A 2AZNA 3QLZA 1LUDA 1PDBA 4QLFA 4ELGA 1HFQA 1JOLA 3FQFA 5HVEA 4DPHA 3JW5A 3QL3A 4XE6X 3DGAA 3M09A 3NTZA 2FZIA 3GHWA 4EIGA 4HA7A 3F91A 4Q0EA 4TU5X 2CIGA 1IA2A 3S7AA 1DHFA 3NZ9X 3QLSA 2G6VA 4QHVA 4DDRA 4PDJA 3EIGA 4G3MA 1DYJA 4CD2A 3FQ0A 1DLRA 3SAIA 2BLAA 2OBCA 3EEKA 3E0BA 5U26A 4OR7A 3FREX 4X5GA 3FQOA 2GD9A 1DREA 1DG8A 1DHIA 3F8YA 3JVXA 3OCHA 1RB2A 3JWCA 3NXVA 4KD7A 2L28A 3JWKA 4KNEA 3TQAA 1U70A 4XRBA 1DR6A 1RB3A 3FQZA 3JW3A 3IA5A 5EAJA 3SH2A 1QZFA 3K2HA 1CZ3A 1RA3A 3OAFA 1VDRA 4PSSA 3CL9A 1RC4A 3K45A 3NZ6X 3FYVX 3QYOA 4QLEA 3S9UA 2D0KA 2W3WA 1OHJA 1SEJA 4NX6A 1DRFA 1M78A 3DL6A 2DHFA 4M7UA 3D84X 3Q1HA 4QLGA 4EIZA 4XT6A 1RX2A 1S3WA 4KEBA 1TDRA 4XT7A 4X5JA 4P68A 4PSTA 3KY8A 4GH8A 4KAKA 1RA9A 3DAUA 3NXOA 4M6LA 3UM6A 3QLWA 3KJSA 5HQZA 3INVA 1DR1A 1CD2A 1D1GA 4QJZD 1M79A 1OHKA 5JG0X 2W3AA 2LF1A 2O7PA 4EILA 4IXED 1RX8A 4FHBA 4KY8A 3CLBA 4P3QA 5HSUA 1RA8A 3QLRA 4KJKA 5HF0X 3SA1A 5HT4A 3IRNA 3QGTA 1U71A 2INQA 1DG7A 3DFRA 1DYHA 4G8ZX 1RX1A 4KM0A 1DDRA 2JYBA 4FGHA 3NZAX 4Q0DA 1LY4A 1DIUA 4PSYA 4ELBA 3FYWX 1DRBA 3IRMA 3SA2A 1AOEA 3DL5A 2HQPA 3F8ZA 3NXTA 1DRHA 1JUVA 1RX4A 3NRRA 5HQYA 4I13A 3NZDA 3QLYA 4KJJA 1KLKA 5ECCA 3I3RA 4QI9A 4HOGA 3K47A 1DRAA 3D80A 4KLXA 3L3RA 2HM9A 4LEKX 5U27A 2ITHA 5DXVA 3SR5X 3SRUX 4KY4A 1RX5A 1YHOA 3QG2A 4RGCA 4G95A 1DR5A 1RF7A 1DISA 3ZPCA 2H2QA 3UM5A 3QFXA 4KBNA 3GHCA 3NZCX 1RX3A 4DPDA 4KYAA 4XECX 3NU0A 3SRRX 3TQ9A 1HFPA 3GI2A 1BZFA 3NXYA 2W9SA 1MVSA 4M6KA 1MVTA 1DR3A 1S3UA 3FRFX 3SRQX 3LG4A 3KJRA 3RG9A 1S3YA 1DR2A 4KL9A 4OSGA 1HFRA 3NXRA 4PTHA 3JSUA 3I8AX 1DF7A 2ANOA 5FDAA 1AI9A 4H98A 4ECKA 3QL0A 3JWFA 4H95A 2W3BA 3N0HA 1LY3A 1J3JA 2BLBA 5CCCA 5HUIA 2FZHA 1DYIA 3TQBA 3JWMA 1DR4A 3JTWA 1DAJA 5JA3A 1U72A 4XT4A 1DYRA 1RH3A 7DFRA 4ELFA 4IXGX 2DRCA 4LAHX 3HJ3A 1IA3A 4I1NA 4IXFX 2ANQA 1KMSA 3F0XX 1RA1A 1RE7A 4H97A 3FQCA 3FL9A 4M7VA 4P66A 2QK8A 2D5NA 1RX6A 1DLSA 2FZJA 1IA1A 1KMVA 3DATA 3FS6A 3F0SX 3GHVA 3CSEA 1PD8A 4LAGX 3CD2A 4M2XA 5HI6A 4Q67A 1E26A 3QYLA 1VJ3A 1J3IA 1DHJA 3EEJA 2KGKA 3NZBX 3K74A 3ROAA 4KJLA 3HBBA 2BL9A 2P4GA 1S3VA 1RX7A 4LAEX 3EEMA 1DG5A 4KFJA 3FL8A 4HOEA 5E8QA 3ZPGA 4X5IA 2W3VA 3F0BX 3QLXA 2BLCA 5HSRA 1J3KA 6DFRA 2C2SA 3DRCA 3KGYA 3SRSX 1RA2A 2ZZAA 3SGYA 2OIPA 4PTJA 3FQVA 3FY8X 4EJ1A 1RD7A 3IX9A 3UM8A 3F0QX 3FRBX 2CD2A 3RO9A 2B3ZA 5HF2X 1JOMA 3F0VX 4NX7A 1RX9A 3IROA 3FY9X 5CC9A 4HA9A 3IA4A 3TD8A 8DFRA 3FRDX 4KM2A 3KFYA 1IA4A 3GYFA 4XT8A 1DDSA 4DP3A 1BOZA 4X5FA 5HPBA 5HT5A 1M7AA 3FRAX 5ECXA 2W9HA 3R33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ELE A;  2C2T A;  4HOF A;  5DFR A;  1RG7 A;  1PD9 A;  5HVB A;  2W9G A;  4X5H A;  3S3V A;  2HXV A;  1AO8 A;  2W3M A;  3NXX A;  4H96 A;  2W9T A;  3F0U X;  4Q6A A;  1ZDR A;  4QJC A;  1DR7 A;  4M6J A;  4P3R A;  3VCO A;  3M08 A;  4XT5 A;  4FGG A;  3DG8 A;  3SQY X;  3SRW X;  3TQ8 A;  4ELH A;  3EEL A;  3EX8 A;  4DFR A;  2XW7 A;  2AZN A;  3QLZ A;  1LUD A;  1PDB A;  4QLF A;  4ELG A;  1HFQ A;  1JOL A;  3FQF A;  5HVE A;  4DPH A;  3JW5 A;  3QL3 A;  4XE6 X;  3DGA A;  3M09 A;  3NTZ A;  2FZI A;  3GHW A;  4EIG A;  4HA7 A;  3F91 A;  4Q0E A;  4TU5 X;  2CIG A;  1IA2 A;  3S7A A;  1DHF A;  3NZ9 X;  3QLS A;  2G6V A;  4QHV A;  4DDR A;  4PDJ A;  3EIG A;  4G3M A;  1DYJ A;  4CD2 A;  3FQ0 A;  1DLR A;  3SAI A;  2BLA A;  2OBC A;  3EEK A;  3E0B A;  5U26 A;  4OR7 A;  3FRE X;  4X5G A;  3FQO A;  2GD9 A;  1DRE A;  1DG8 A;  1DHI A;  3F8Y A;  3JVX A;  3OCH A;  1RB2 A;  3JWC A;  3NXV A;  4KD7 A;  2L28 A;  3JWK A;  4KNE A;  3TQA A;  1U70 A;  4XRB A;  1DR6 A;  1RB3 A;  3FQZ A;  3JW3 A;  3IA5 A;  5EAJ A;  3SH2 A;  1QZF A;  3K2H A;  1CZ3 A;  1RA3 A;  3OAF A;  1VDR A;  4PSS A;  3CL9 A;  1RC4 A;  3K45 A;  3NZ6 X;  3FYV X;  3QYO A;  4QLE A;  3S9U A;  2D0K A;  2W3W A;  1OHJ A;  1SEJ A;  4NX6 A;  1DRF A;  1M78 A;  3DL6 A;  2DHF A;  4M7U A;  3D84 X;  3Q1H A;  4QLG A;  4EIZ A;  4XT6 A;  1RX2 A;  1S3W A;  4KEB A;  1TDR A;  4XT7 A;  4X5J A;  4P68 A;  4PST A;  3KY8 A;  4GH8 A;  4KAK A;  1RA9 A;  3DAU A;  3NXO A;  4M6L A;  3UM6 A;  3QLW A;  3KJS A;  5HQZ A;  3INV A;  1DR1 A;  1CD2 A;  1D1G A;  4QJZ D;  1M79 A;  1OHK A;  5JG0 X;  2W3A A;  2LF1 A;  2O7P A;  4EIL A;  4IXE D;  1RX8 A;  4FHB A;  4KY8 A;  3CLB A;  4P3Q A;  5HSU A;  1RA8 A;  3QLR A;  4KJK A;  5HF0 X;  3SA1 A;  5HT4 A;  3IRN A;  3QGT A;  1U71 A;  2INQ A;  1DG7 A;  3DFR A;  1DYH A;  4G8Z X;  1RX1 A;  4KM0 A;  1DDR A;  2JYB A;  4FGH A;  3NZA X;  4Q0D A;  1LY4 A;  1DIU A;  4PSY A;  4ELB A;  3FYW X;  1DRB A;  3IRM A;  3SA2 A;  1AOE A;  3DL5 A;  2HQP A;  3F8Z A;  3NXT A;  1DRH A;  1JUV A;  1RX4 A;  3NRR A;  5HQY A;  4I13 A;  3NZD A;  3QLY A;  4KJJ A;  1KLK A;  5ECC A;  3I3R A;  4QI9 A;  4HOG A;  3K47 A;  1DRA A;  3D80 A;  4KLX A;  3L3R A;  2HM9 A;  4LEK X;  5U27 A;  2ITH A;  5DXV A;  3SR5 X;  3SRU X;  4KY4 A;  1RX5 A;  1YHO A;  3QG2 A;  4RGC A;  4G95 A;  1DR5 A;  1RF7 A;  1DIS A;  3ZPC A;  2H2Q A;  3UM5 A;  3QFX A;  4KBN A;  3GHC A;  3NZC X;  1RX3 A;  4DPD A;  4KYA A;  4XEC X;  3NU0 A;  3SRR X;  3TQ9 A;  1HFP A;  3GI2 A;  1BZF A;  3NXY A;  2W9S A;  1MVS A;  4M6K A;  1MVT A;  1DR3 A;  1S3U A;  3FRF X;  3SRQ X;  3LG4 A;  3KJR A;  3RG9 A;  1S3Y A;  1DR2 A;  4KL9 A;  4OSG A;  1HFR A;  3NXR A;  4PTH A;  3JSU A;  3I8A X;  1DF7 A;  2ANO A;  5FDA A;  1AI9 A;  4H98 A;  4ECK A;  3QL0 A;  3JWF A;  4H95 A;  2W3B A;  3N0H A;  1LY3 A;  1J3J A;  2BLB A;  5CCC A;  5HUI A;  2FZH A;  1DYI A;  3TQB A;  3JWM A;  1DR4 A;  3JTW A;  1DAJ A;  5JA3 A;  1U72 A;  4XT4 A;  1DYR A;  1RH3 A;  7DFR A;  4ELF A;  4IXG X;  2DRC A;  4LAH X;  3HJ3 A;  1IA3 A;  4I1N A;  4IXF X;  2ANQ A;  1KMS A;  3F0X X;  1RA1 A;  1RE7 A;  4H97 A;  3FQC A;  3FL9 A;  4M7V A;  4P66 A;  2QK8 A;  2D5N A;  1RX6 A;  1DLS A;  2FZJ A;  1IA1 A;  1KMV A;  3DAT A;  3FS6 A;  3F0S X;  3GHV A;  3CSE A;  1PD8 A;  4LAG X;  3CD2 A;  4M2X A;  5HI6 A;  4Q67 A;  1E26 A;  3QYL A;  1VJ3 A;  1J3I A;  1DHJ A;  3EEJ A;  2KGK A;  3NZB X;  3K74 A;  3ROA A;  4KJL A;  3HBB A;  2BL9 A;  2P4G A;  1S3V A;  1RX7 A;  4LAE X;  3EEM A;  1DG5 A;  4KFJ A;  3FL8 A;  4HOE A;  5E8Q A;  3ZPG A;  4X5I A;  2W3V A;  3F0B X;  3QLX A;  2BLC A;  5HSR A;  1J3K A;  6DFR A;  2C2S A;  3DRC A;  3KGY A;  3SRS X;  1RA2 A;  2ZZA A;  3SGY A;  2OIP A;  4PTJ A;  3FQV A;  3FY8 X;  4EJ1 A;  1RD7 A;  3IX9 A;  3UM8 A;  3F0Q X;  3FRB X;  2CD2 A;  3RO9 A;  2B3Z A;  5HF2 X;  1JOM A;  3F0V X;  4NX7 A;  1RX9 A;  3IRO A;  3FY9 X;  5CC9 A;  4HA9 A;  3IA4 A;  3TD8 A;  8DFR A;  3FRD X;  4KM2 A;  3KFY A;  1IA4 A;  3GYF A;  4XT8 A;  1DDS A;  4DP3 A;  1BOZ A;  4X5F A;  5HPB A;  5HT5 A;  1M7A A;  3FRA X;  5ECX A;  2W9H A;  3R33 A; 
#chains in the Genus database with same CATH topology
 4ELE A;  2C2T A;  4HOF A;  5DFR A;  1RG7 A;  1PD9 A;  5HVB A;  2W9G A;  4X5H A;  3S3V A;  2HXV A;  1AO8 A;  2W3M A;  3NXX A;  4H96 A;  2W9T A;  3F0U X;  4Q6A A;  1ZDR A;  4QJC A;  1DR7 A;  4M6J A;  4P3R A;  3VCO A;  3M08 A;  4XT5 A;  4FGG A;  3DG8 A;  3SQY X;  3SRW X;  3TQ8 A;  4ELH A;  3EEL A;  3EX8 A;  4DFR A;  2XW7 A;  2AZN A;  3QLZ A;  1LUD A;  1PDB A;  4QLF A;  4ELG A;  1HFQ A;  1JOL A;  3FQF A;  5HVE A;  4DPH A;  3JW5 A;  3QL3 A;  4XE6 X;  3DGA A;  3M09 A;  3NTZ A;  2FZI A;  3GHW A;  4EIG A;  4HA7 A;  3F91 A;  4Q0E A;  4TU5 X;  2CIG A;  1IA2 A;  3S7A A;  1DHF A;  3NZ9 X;  3QLS A;  2G6V A;  4QHV A;  4DDR A;  4PDJ A;  3EIG A;  4G3M A;  1DYJ A;  4CD2 A;  3FQ0 A;  1DLR A;  3SAI A;  2BLA A;  2OBC A;  3EEK A;  3E0B A;  5U26 A;  4OR7 A;  3FRE X;  4X5G A;  3FQO A;  2GD9 A;  1DRE A;  1DG8 A;  1DHI A;  3F8Y A;  3JVX A;  3OCH A;  1RB2 A;  3JWC A;  3NXV A;  4KD7 A;  2L28 A;  3JWK A;  4KNE A;  3TQA A;  1U70 A;  4XRB A;  1DR6 A;  1RB3 A;  3FQZ A;  3JW3 A;  3IA5 A;  5EAJ A;  3SH2 A;  1QZF A;  3K2H A;  1CZ3 A;  1RA3 A;  3OAF A;  1VDR A;  4PSS A;  3CL9 A;  1RC4 A;  3K45 A;  3NZ6 X;  3FYV X;  3QYO A;  4QLE A;  3S9U A;  2D0K A;  2W3W A;  1OHJ A;  1SEJ A;  4NX6 A;  1DRF A;  1M78 A;  3DL6 A;  2DHF A;  4M7U A;  3D84 X;  3Q1H A;  4QLG A;  4EIZ A;  4XT6 A;  1RX2 A;  1S3W A;  4KEB A;  1TDR A;  4XT7 A;  4X5J A;  4P68 A;  4PST A;  3KY8 A;  4GH8 A;  4KAK A;  1RA9 A;  3DAU A;  3NXO A;  4M6L A;  3UM6 A;  3QLW A;  3KJS A;  5HQZ A;  3INV A;  1DR1 A;  1CD2 A;  1D1G A;  4QJZ D;  1M79 A;  1OHK A;  5JG0 X;  2W3A A;  2LF1 A;  2O7P A;  4EIL A;  4IXE D;  1RX8 A;  4FHB A;  4KY8 A;  3CLB A;  4P3Q A;  5HSU A;  1RA8 A;  3QLR A;  4KJK A;  5HF0 X;  3SA1 A;  5HT4 A;  3IRN A;  3QGT A;  1U71 A;  2INQ A;  1DG7 A;  3DFR A;  1DYH A;  4G8Z X;  1RX1 A;  4KM0 A;  1DDR A;  2JYB A;  4FGH A;  3NZA X;  4Q0D A;  1LY4 A;  1DIU A;  4PSY A;  4ELB A;  3FYW X;  1DRB A;  3IRM A;  3SA2 A;  1AOE A;  3DL5 A;  2HQP A;  3F8Z A;  3NXT A;  1DRH A;  1JUV A;  1RX4 A;  3NRR A;  5HQY A;  4I13 A;  3NZD A;  3QLY A;  4KJJ A;  1KLK A;  5ECC A;  3I3R A;  4QI9 A;  4HOG A;  3K47 A;  1DRA A;  3D80 A;  4KLX A;  3L3R A;  2HM9 A;  4LEK X;  5U27 A;  2ITH A;  5DXV A;  3SR5 X;  3SRU X;  4KY4 A;  1RX5 A;  1YHO A;  3QG2 A;  4RGC A;  4G95 A;  1DR5 A;  1RF7 A;  1DIS A;  3ZPC A;  2H2Q A;  3UM5 A;  3QFX A;  4KBN A;  3GHC A;  3NZC X;  1RX3 A;  4DPD A;  4KYA A;  4XEC X;  3NU0 A;  3SRR X;  3TQ9 A;  1HFP A;  3GI2 A;  1BZF A;  3NXY A;  2W9S A;  1MVS A;  4M6K A;  1MVT A;  1DR3 A;  1S3U A;  3FRF X;  3SRQ X;  3LG4 A;  3KJR A;  3RG9 A;  1S3Y A;  1DR2 A;  4KL9 A;  4OSG A;  1HFR A;  3NXR A;  4PTH A;  3JSU A;  3I8A X;  1DF7 A;  2ANO A;  5FDA A;  1AI9 A;  4H98 A;  4ECK A;  3QL0 A;  3JWF A;  4H95 A;  2W3B A;  3N0H A;  1LY3 A;  1J3J A;  2BLB A;  5CCC A;  5HUI A;  2FZH A;  1DYI A;  3TQB A;  3JWM A;  1DR4 A;  3JTW A;  1DAJ A;  5JA3 A;  1U72 A;  4XT4 A;  1DYR A;  1RH3 A;  7DFR A;  4ELF A;  4IXG X;  2DRC A;  4LAH X;  3HJ3 A;  1IA3 A;  4I1N A;  4IXF X;  2ANQ A;  1KMS A;  3F0X X;  1RA1 A;  1RE7 A;  4H97 A;  3FQC A;  3FL9 A;  4M7V A;  4P66 A;  2QK8 A;  2D5N A;  1RX6 A;  1DLS A;  2FZJ A;  1IA1 A;  1KMV A;  3DAT A;  3FS6 A;  3F0S X;  3GHV A;  3CSE A;  1PD8 A;  4LAG X;  3CD2 A;  4M2X A;  5HI6 A;  4Q67 A;  1E26 A;  3QYL A;  1VJ3 A;  1J3I A;  1DHJ A;  3EEJ A;  2KGK A;  3NZB X;  3K74 A;  3ROA A;  4KJL A;  3HBB A;  2BL9 A;  2P4G A;  1S3V A;  1RX7 A;  4LAE X;  3EEM A;  1DG5 A;  4KFJ A;  3FL8 A;  4HOE A;  5E8Q A;  3ZPG A;  4X5I A;  2W3V A;  3F0B X;  3QLX A;  2BLC A;  5HSR A;  1J3K A;  6DFR A;  2C2S A;  3DRC A;  3KGY A;  3SRS X;  1RA2 A;  2ZZA A;  3SGY A;  2OIP A;  4PTJ A;  3FQV A;  3FY8 X;  4EJ1 A;  1RD7 A;  3IX9 A;  3UM8 A;  3F0Q X;  3FRB X;  2CD2 A;  3RO9 A;  2B3Z A;  5HF2 X;  1JOM A;  3F0V X;  4NX7 A;  1RX9 A;  3IRO A;  3FY9 X;  5CC9 A;  4HA9 A;  3IA4 A;  3TD8 A;  8DFR A;  3FRD X;  4KM2 A;  3KFY A;  1IA4 A;  3GYF A;  4XT8 A;  1DDS A;  4DP3 A;  1BOZ A;  4X5F A;  5HPB A;  5HT5 A;  1M7A A;  3FRA X;  5ECX A;  2W9H A;  3R33 A; 
#chains in the Genus database with same CATH homology
 4ELE A;  2C2T A;  4HOF A;  5DFR A;  1RG7 A;  1PD9 A;  5HVB A;  2W9G A;  4X5H A;  3S3V A;  2HXV A;  1AO8 A;  2W3M A;  3NXX A;  4H96 A;  2W9T A;  3F0U X;  4Q6A A;  1ZDR A;  4QJC A;  1DR7 A;  4M6J A;  4P3R A;  3VCO A;  3M08 A;  4XT5 A;  4FGG A;  3DG8 A;  3SQY X;  3SRW X;  3TQ8 A;  4ELH A;  3EEL A;  3EX8 A;  4DFR A;  2XW7 A;  2AZN A;  3QLZ A;  1LUD A;  1PDB A;  4QLF A;  4ELG A;  1HFQ A;  1JOL A;  3FQF A;  5HVE A;  4DPH A;  3JW5 A;  3QL3 A;  4XE6 X;  3DGA A;  3M09 A;  3NTZ A;  2FZI A;  3GHW A;  4EIG A;  4HA7 A;  3F91 A;  4Q0E A;  4TU5 X;  2CIG A;  1IA2 A;  3S7A A;  1DHF A;  3NZ9 X;  3QLS A;  2G6V A;  4QHV A;  4DDR A;  4PDJ A;  3EIG A;  4G3M A;  1DYJ A;  4CD2 A;  3FQ0 A;  1DLR A;  3SAI A;  2BLA A;  2OBC A;  3EEK A;  3E0B A;  5U26 A;  4OR7 A;  3FRE X;  4X5G A;  3FQO A;  2GD9 A;  1DRE A;  1DG8 A;  1DHI A;  3F8Y A;  3JVX A;  3OCH A;  1RB2 A;  3JWC A;  3NXV A;  4KD7 A;  2L28 A;  3JWK A;  4KNE A;  3TQA A;  1U70 A;  4XRB A;  1DR6 A;  1RB3 A;  3FQZ A;  3JW3 A;  3IA5 A;  5EAJ A;  3SH2 A;  1QZF A;  3K2H A;  1CZ3 A;  1RA3 A;  3OAF A;  1VDR A;  4PSS A;  3CL9 A;  1RC4 A;  3K45 A;  3NZ6 X;  3FYV X;  3QYO A;  4QLE A;  3S9U A;  2D0K A;  2W3W A;  1OHJ A;  1SEJ A;  4NX6 A;  1DRF A;  1M78 A;  3DL6 A;  2DHF A;  4M7U A;  3D84 X;  3Q1H A;  4QLG A;  4EIZ A;  4XT6 A;  1RX2 A;  1S3W A;  4KEB A;  1TDR A;  4XT7 A;  4X5J A;  4P68 A;  4PST A;  3KY8 A;  4GH8 A;  4KAK A;  1RA9 A;  3DAU A;  3NXO A;  4M6L A;  3UM6 A;  3QLW A;  3KJS A;  5HQZ A;  3INV A;  1DR1 A;  1CD2 A;  1D1G A;  4QJZ D;  1M79 A;  1OHK A;  5JG0 X;  2W3A A;  2LF1 A;  2O7P A;  4EIL A;  4IXE D;  1RX8 A;  4FHB A;  4KY8 A;  3CLB A;  4P3Q A;  5HSU A;  1RA8 A;  3QLR A;  4KJK A;  5HF0 X;  3SA1 A;  5HT4 A;  3IRN A;  3QGT A;  1U71 A;  2INQ A;  1DG7 A;  3DFR A;  1DYH A;  4G8Z X;  1RX1 A;  4KM0 A;  1DDR A;  2JYB A;  4FGH A;  3NZA X;  4Q0D A;  1LY4 A;  1DIU A;  4PSY A;  4ELB A;  3FYW X;  1DRB A;  3IRM A;  3SA2 A;  1AOE A;  3DL5 A;  2HQP A;  3F8Z A;  3NXT A;  1DRH A;  1JUV A;  1RX4 A;  3NRR A;  5HQY A;  4I13 A;  3NZD A;  3QLY A;  4KJJ A;  1KLK A;  5ECC A;  3I3R A;  4QI9 A;  4HOG A;  3K47 A;  1DRA A;  3D80 A;  4KLX A;  3L3R A;  2HM9 A;  4LEK X;  5U27 A;  2ITH A;  5DXV A;  3SR5 X;  3SRU X;  4KY4 A;  1RX5 A;  1YHO A;  3QG2 A;  4RGC A;  4G95 A;  1DR5 A;  1RF7 A;  1DIS A;  3ZPC A;  2H2Q A;  3UM5 A;  3QFX A;  4KBN A;  3GHC A;  3NZC X;  1RX3 A;  4DPD A;  4KYA A;  4XEC X;  3NU0 A;  3SRR X;  3TQ9 A;  1HFP A;  3GI2 A;  1BZF A;  3NXY A;  2W9S A;  1MVS A;  4M6K A;  1MVT A;  1DR3 A;  1S3U A;  3FRF X;  3SRQ X;  3LG4 A;  3KJR A;  3RG9 A;  1S3Y A;  1DR2 A;  4KL9 A;  4OSG A;  1HFR A;  3NXR A;  4PTH A;  3JSU A;  3I8A X;  1DF7 A;  2ANO A;  5FDA A;  1AI9 A;  4H98 A;  4ECK A;  3QL0 A;  3JWF A;  4H95 A;  2W3B A;  3N0H A;  1LY3 A;  1J3J A;  2BLB A;  5CCC A;  5HUI A;  2FZH A;  1DYI A;  3TQB A;  3JWM A;  1DR4 A;  3JTW A;  1DAJ A;  5JA3 A;  1U72 A;  4XT4 A;  1DYR A;  1RH3 A;  7DFR A;  4ELF A;  4IXG X;  2DRC A;  4LAH X;  3HJ3 A;  1IA3 A;  4I1N A;  4IXF X;  2ANQ A;  1KMS A;  3F0X X;  1RA1 A;  1RE7 A;  4H97 A;  3FQC A;  3FL9 A;  4M7V A;  4P66 A;  2QK8 A;  2D5N A;  1RX6 A;  1DLS A;  2FZJ A;  1IA1 A;  1KMV A;  3DAT A;  3FS6 A;  3F0S X;  3GHV A;  3CSE A;  1PD8 A;  4LAG X;  3CD2 A;  4M2X A;  5HI6 A;  4Q67 A;  1E26 A;  3QYL A;  1VJ3 A;  1J3I A;  1DHJ A;  3EEJ A;  2KGK A;  3NZB X;  3K74 A;  3ROA A;  4KJL A;  3HBB A;  2BL9 A;  2P4G A;  1S3V A;  1RX7 A;  4LAE X;  3EEM A;  1DG5 A;  4KFJ A;  3FL8 A;  4HOE A;  5E8Q A;  3ZPG A;  4X5I A;  2W3V A;  3F0B X;  3QLX A;  2BLC A;  5HSR A;  1J3K A;  6DFR A;  2C2S A;  3DRC A;  3KGY A;  3SRS X;  1RA2 A;  2ZZA A;  3SGY A;  2OIP A;  4PTJ A;  3FQV A;  3FY8 X;  4EJ1 A;  1RD7 A;  3IX9 A;  3UM8 A;  3F0Q X;  3FRB X;  2CD2 A;  3RO9 A;  2B3Z A;  5HF2 X;  1JOM A;  3F0V X;  4NX7 A;  1RX9 A;  3IRO A;  3FY9 X;  5CC9 A;  4HA9 A;  3IA4 A;  3TD8 A;  8DFR A;  3FRD X;  4KM2 A;  3KFY A;  1IA4 A;  3GYF A;  4XT8 A;  1DDS A;  4DP3 A;  1BOZ A;  4X5F A;  5HPB A;  5HT5 A;  1M7A A;  3FRA X;  5ECX A;  2W9H A;  3R33 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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