2W9TA

Staphylococcus aureus s1:dhfr
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
159
structure length
159
Chain Sequence
TLSIIVAHDKQRVIGYQNQLPWHLPNDLKHIKQLTTGNTLVMARKTFESIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLYEAMIDQVDDMYITVIDGKFQGDTFFPPYTFEDWEVESSVEGQLDEKNTIPHTFLHLVRRKG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Comparison of Chromosomal and Exogenous Dihydrofolate Reductase from Staphylococcus Aureus in Complex with the Potent Inhibitor Trimethoprim.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus
molecule keywords DIHYDROFOLATE REDUCTASE TYPE 1
total genus 42
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 2w9tA00
4HA7A 2LF1A 1VJ3A 1LY4A 5HQYA 1DHIA 5U27A 5HT4A 2H2QA 3EIGA 3RG9A 4HOEA 4GH8A 1S3UA 4QHVA 3FY8X 4X5FA 3NXXA 3IRMA 3S9UA 2G6VA 2ANQA 1JOMA 5ECCA 4HA9A 2W3VA 1RX3A 2CD2A 2L28A 5FDAA 3NTZA 4IXFX 4HOGA 4QLGA 4FGHA 3DATA 3QLRA 3S7AA 3QL3A 1DR7A 1DG5A 1DREA 2FZHA 3DAUA 1PD8A 1PD9A 1JUVA 4EIZA 4ELHA 1LY3A 3K45A 3SH2A 5HQZA 3DRCA 3E0BA 1RF7A 1DLRA 5HF2X 3ZPCA 3DG8A 3FRBX 4X5JA 1RB3A 4IXED 4P3QA 4QLFA 7DFRA 4KNEA 3F0BX 2AZNA 3DL6A 3FQCA 3NZ9X 4ELEA 3UM5A 2BL9A 5HF0X 1DRFA 1RB2A 1RX9A 1U70A 2BLCA 1DR4A 3FQFA 3FY9X 4ELGA 4KJKA 4FGGA 5HSUA 1ZDRA 3SA1A 4X5IA 2GD9A 4PTHA 3SQYX 3N0HA 1IA3A 3F0UX 1DAJA 1DDRA 3QGTA 1RA8A 3CD2A 3IX9A 3JWFA 3TQAA 4KJLA 4PSYA 3F8ZA 3FL9A 1DG8A 1OHKA 2W3BA 4DPDA 4ECKA 3Q1HA 1DR6A 3F8YA 5CCCA 1JOLA 1OHJA 1HFQA 3DGAA 4XT7A 3NXOA 4EJ1A 3QL0A 3DFRA 3OCHA 4KM0A 3DL5A 3FQOA 2D0KA 2KGKA 4KL9A 4QJCA 3NZAX 1J3IA 3QLZA 4RGCA 1RX6A 3RO9A 2ITHA 3FYWX 2B3ZA 4NX7A 3F0VX 1S3YA 2ZZAA 1HFPA 4PSTA 3K47A 1RX5A 4M7UA 4XT6A 4X5HA 3D84X 3JSUA 4KY4A 1RX8A 3R33A 1S3VA 1DRAA 3NRRA 1DYHA 3KGYA 4G95A 3IROA 4ELFA 3VCOA 1PDBA 3JTWA 4LAHX 5DXVA 4M6LA 4XT8A 3NZ6X 5HPBA 3UM8A 4KAKA 1RA9A 1RE7A 3GI2A 5HI6A 4HOFA 3CL9A 3EEKA 3SA2A 3F0XX 5HVBA 3M09A 3KFYA 4M6KA 4TU5X 4KBNA 3SAIA 3FREX 3GHWA 3QLWA 3GYFA 2OIPA 4P68A 5EAJA 6DFRA 4FHBA 4EILA 3FRDX 4OSGA 4PSSA 1RX7A 5JG0X 3HJ3A 1CD2A 3FS6A 4CD2A 3NXTA 4DDRA 1DYRA 4G3MA 5HSRA 3M08A 1DLSA 5CC9A 2DHFA 1IA4A 2QK8A 1DF7A 4KJJA 4Q0EA 4KEBA 3NZCX 3SRQX 4P66A 1BZFA 2W3AA 3QLYA 3F0SX 3FRFX 4G8ZX 1AI9A 1RD7A 4H95A 1DR1A 5HT5A 3UM6A 1U71A 3JWCA 4I1NA 3EEMA 1S3WA 3EX8A 3FRAX 1BOZA 3F0QX 3NU0A 3QFXA 3NXYA 1J3KA 4KYAA 4Q67A 1SEJA 2HM9A 3FQVA 4KD7A 1IA1A 2FZJA 1MVSA 1DYJA 3QG2A 3CLBA 4PTJA 1D1GA 1RA2A 4OR7A 4H98A 4P3RA 4KY8A 3IRNA 1RX2A 3IA4A 2DRCA 2W9SA 4ELBA 3I8AX 2BLAA 3K74A 3SGYA 1M78A 1MVTA 3FQZA 1IA2A 1DDSA 1CZ3A 2OBCA 1DYIA 1HFRA 3KY8A 5DFRA 1DHJA 4M2XA 5HVEA 4EIGA 1DRHA 3LG4A 4XT5A 4NX6A 2XW7A 5E8QA 1J3JA 3GHVA 2W3WA 2D5NA 2W9TA 3ZPGA 3QLXA 1DR2A 8DFRA 4I13A 3KJRA 4XT4A 1AOEA 2JYBA 3FYVX 4DP3A 3NZDA 1U72A 4QI9A 3NXRA 2HQPA 3INVA 3D80A 1YHOA 3SR5X 1M7AA 3HBBA 3JVXA 2INQA 3TQ8A 3L3RA 4XE6X 1TDRA 3KJSA 1DG7A 1QZFA 3JWMA 3EELA 3JW5A 1DISA 3JW3A 2W9HA 2C2TA 2FZIA 3S3VA 3TD8A 5U26A 3NZBX 4DPHA 3QLSA 1DHFA 3NXVA 4XECX 4DFRA 1RA1A 1M79A 1RA3A 2P4GA 4IXGX 4X5GA 2HXVA 3GHCA 4LAGX 4QLEA 2C2SA 1LUDA 1RG7A 4M6JA 1DR5A 1DIUA 1DR3A 4Q0DA 3SRUX 3OAFA 3FL8A 1E26A 2CIGA 3TQ9A 3SRRX 5JA3A 1DRBA 1RX4A 2O7PA 3SRSX 4QJZD 3ROAA 5ECXA 1KMSA 3I3RA 1RC4A 4M7VA 3EEJA 4H97A 4LEKX 3IA5A 1RH3A 4KM2A 4KFJA 2W9GA 3TQBA 1KLKA 2BLBA 3K2HA 2ANOA 1AO8A 2W3MA 5HUIA 4PDJA 3F91A 1KMVA 4H96A 3QYOA 1VDRA 4LAEX 3SRWX 3QYLA 4KLXA 4XRBA 3CSEA 3FQ0A 4Q6AA 3JWKA 1RX1A
chains in the Genus database with same CATH superfamily
4HA7A 2LF1A 1VJ3A 1LY4A 5HQYA 1DHIA 5U27A 5HT4A 2H2QA 3EIGA 3RG9A 4HOEA 4GH8A 1S3UA 4QHVA 3FY8X 4X5FA 3NXXA 3IRMA 3S9UA 2G6VA 2ANQA 1JOMA 5ECCA 4HA9A 2W3VA 1RX3A 2CD2A 2L28A 5FDAA 3NTZA 4IXFX 4HOGA 4QLGA 4FGHA 3DATA 3QLRA 3S7AA 3QL3A 1DR7A 1DG5A 1DREA 2FZHA 3DAUA 1PD8A 1PD9A 1JUVA 4EIZA 4ELHA 1LY3A 3K45A 3SH2A 5HQZA 3DRCA 3E0BA 1RF7A 1DLRA 5HF2X 3ZPCA 3DG8A 3FRBX 4X5JA 1RB3A 4IXED 4P3QA 4QLFA 7DFRA 4KNEA 3F0BX 2AZNA 3DL6A 3FQCA 3NZ9X 4ELEA 3UM5A 2BL9A 5HF0X 1DRFA 1RB2A 1RX9A 1U70A 2BLCA 1DR4A 3FQFA 3FY9X 4ELGA 4KJKA 4FGGA 5HSUA 1ZDRA 3SA1A 4X5IA 2GD9A 4PTHA 3SQYX 3N0HA 1IA3A 3F0UX 1DAJA 1DDRA 3QGTA 1RA8A 3CD2A 3IX9A 3JWFA 3TQAA 4KJLA 4PSYA 3F8ZA 3FL9A 1DG8A 1OHKA 2W3BA 4DPDA 4ECKA 3Q1HA 1DR6A 3F8YA 5CCCA 1JOLA 1OHJA 1HFQA 3DGAA 4XT7A 3NXOA 4EJ1A 3QL0A 3DFRA 3OCHA 4KM0A 3DL5A 3FQOA 2D0KA 2KGKA 4KL9A 4QJCA 3NZAX 1J3IA 3QLZA 4RGCA 1RX6A 3RO9A 2ITHA 3FYWX 2B3ZA 4NX7A 3F0VX 1S3YA 2ZZAA 1HFPA 4PSTA 3K47A 1RX5A 4M7UA 4XT6A 4X5HA 3D84X 3JSUA 4KY4A 1RX8A 3R33A 1S3VA 1DRAA 3NRRA 1DYHA 3KGYA 4G95A 3IROA 4ELFA 3VCOA 1PDBA 3JTWA 4LAHX 5DXVA 4M6LA 4XT8A 3NZ6X 5HPBA 3UM8A 4KAKA 1RA9A 1RE7A 3GI2A 5HI6A 4HOFA 3CL9A 3EEKA 3SA2A 3F0XX 5HVBA 3M09A 3KFYA 4M6KA 4TU5X 4KBNA 3SAIA 3FREX 3GHWA 3QLWA 3GYFA 2OIPA 4P68A 5EAJA 6DFRA 4FHBA 4EILA 3FRDX 4OSGA 4PSSA 1RX7A 5JG0X 3HJ3A 1CD2A 3FS6A 4CD2A 3NXTA 4DDRA 1DYRA 4G3MA 5HSRA 3M08A 1DLSA 5CC9A 2DHFA 1IA4A 2QK8A 1DF7A 4KJJA 4Q0EA 4KEBA 3NZCX 3SRQX 4P66A 1BZFA 2W3AA 3QLYA 3F0SX 3FRFX 4G8ZX 1AI9A 1RD7A 4H95A 1DR1A 5HT5A 3UM6A 1U71A 3JWCA 4I1NA 3EEMA 1S3WA 3EX8A 3FRAX 1BOZA 3F0QX 3NU0A 3QFXA 3NXYA 1J3KA 4KYAA 4Q67A 1SEJA 2HM9A 3FQVA 4KD7A 1IA1A 2FZJA 1MVSA 1DYJA 3QG2A 3CLBA 4PTJA 1D1GA 1RA2A 4OR7A 4H98A 4P3RA 4KY8A 3IRNA 1RX2A 3IA4A 2DRCA 2W9SA 4ELBA 3I8AX 2BLAA 3K74A 3SGYA 1M78A 1MVTA 3FQZA 1IA2A 1DDSA 1CZ3A 2OBCA 1DYIA 1HFRA 3KY8A 5DFRA 1DHJA 4M2XA 5HVEA 4EIGA 1DRHA 3LG4A 4XT5A 4NX6A 2XW7A 5E8QA 1J3JA 3GHVA 2W3WA 2D5NA 2W9TA 3ZPGA 3QLXA 1DR2A 8DFRA 4I13A 3KJRA 4XT4A 1AOEA 2JYBA 3FYVX 4DP3A 3NZDA 1U72A 4QI9A 3NXRA 2HQPA 3INVA 3D80A 1YHOA 3SR5X 1M7AA 3HBBA 3JVXA 2INQA 3TQ8A 3L3RA 4XE6X 1TDRA 3KJSA 1DG7A 1QZFA 3JWMA 3EELA 3JW5A 1DISA 3JW3A 2W9HA 2C2TA 2FZIA 3S3VA 3TD8A 5U26A 3NZBX 4DPHA 3QLSA 1DHFA 3NXVA 4XECX 4DFRA 1RA1A 1M79A 1RA3A 2P4GA 4IXGX 4X5GA 2HXVA 3GHCA 4LAGX 4QLEA 2C2SA 1LUDA 1RG7A 4M6JA 1DR5A 1DIUA 1DR3A 4Q0DA 3SRUX 3OAFA 3FL8A 1E26A 2CIGA 3TQ9A 3SRRX 5JA3A 1DRBA 1RX4A 2O7PA 3SRSX 4QJZD 3ROAA 5ECXA 1KMSA 3I3RA 1RC4A 4M7VA 3EEJA 4H97A 4LEKX 3IA5A 1RH3A 4KM2A 4KFJA 2W9GA 3TQBA 1KLKA 2BLBA 3K2HA 2ANOA 1AO8A 2W3MA 5HUIA 4PDJA 3F91A 1KMVA 4H96A 3QYOA 1VDRA 4LAEX 3SRWX 3QYLA 4KLXA 4XRBA 3CSEA 3FQ0A 4Q6AA 3JWKA 1RX1A
chains in the Genus database with same CATH topology
4HA7A 2LF1A 1VJ3A 1LY4A 5HQYA 1DHIA 5U27A 5HT4A 2H2QA 3EIGA 3RG9A 4HOEA 4GH8A 1S3UA 4QHVA 3FY8X 4X5FA 3NXXA 3IRMA 3S9UA 2G6VA 2ANQA 1JOMA 5ECCA 4HA9A 2W3VA 1RX3A 2CD2A 2L28A 5FDAA 3NTZA 4IXFX 4HOGA 4QLGA 4FGHA 3DATA 3QLRA 3S7AA 3QL3A 1DR7A 1DG5A 1DREA 2FZHA 3DAUA 1PD8A 1PD9A 1JUVA 4EIZA 4ELHA 1LY3A 3K45A 3SH2A 5HQZA 3DRCA 3E0BA 1RF7A 1DLRA 5HF2X 3ZPCA 3DG8A 3FRBX 4X5JA 1RB3A 4IXED 4P3QA 4QLFA 7DFRA 4KNEA 3F0BX 2AZNA 3DL6A 3FQCA 3NZ9X 4ELEA 3UM5A 2BL9A 5HF0X 1DRFA 1RB2A 1RX9A 1U70A 2BLCA 1DR4A 3FQFA 3FY9X 4ELGA 4KJKA 4FGGA 5HSUA 1ZDRA 3SA1A 4X5IA 2GD9A 4PTHA 3SQYX 3N0HA 1IA3A 3F0UX 1DAJA 1DDRA 3QGTA 1RA8A 3CD2A 3IX9A 3JWFA 3TQAA 4KJLA 4PSYA 3F8ZA 3FL9A 1DG8A 1OHKA 2W3BA 4DPDA 4ECKA 3Q1HA 1DR6A 3F8YA 5CCCA 1JOLA 1OHJA 1HFQA 3DGAA 4XT7A 3NXOA 4EJ1A 3QL0A 3DFRA 3OCHA 4KM0A 3DL5A 3FQOA 2D0KA 2KGKA 4KL9A 4QJCA 3NZAX 1J3IA 3QLZA 4RGCA 1RX6A 3RO9A 2ITHA 3FYWX 2B3ZA 4NX7A 3F0VX 1S3YA 2ZZAA 1HFPA 4PSTA 3K47A 1RX5A 4M7UA 4XT6A 4X5HA 3D84X 3JSUA 4KY4A 1RX8A 3R33A 1S3VA 1DRAA 3NRRA 1DYHA 3KGYA 4G95A 3IROA 4ELFA 3VCOA 1PDBA 3JTWA 4LAHX 5DXVA 4M6LA 4XT8A 3NZ6X 5HPBA 3UM8A 4KAKA 1RA9A 1RE7A 3GI2A 5HI6A 4HOFA 3CL9A 3EEKA 3SA2A 3F0XX 5HVBA 3M09A 3KFYA 4M6KA 4TU5X 4KBNA 3SAIA 3FREX 3GHWA 3QLWA 3GYFA 2OIPA 4P68A 5EAJA 6DFRA 4FHBA 4EILA 3FRDX 4OSGA 4PSSA 1RX7A 5JG0X 3HJ3A 1CD2A 3FS6A 4CD2A 3NXTA 4DDRA 1DYRA 4G3MA 5HSRA 3M08A 1DLSA 5CC9A 2DHFA 1IA4A 2QK8A 1DF7A 4KJJA 4Q0EA 4KEBA 3NZCX 3SRQX 4P66A 1BZFA 2W3AA 3QLYA 3F0SX 3FRFX 4G8ZX 1AI9A 1RD7A 4H95A 1DR1A 5HT5A 3UM6A 1U71A 3JWCA 4I1NA 3EEMA 1S3WA 3EX8A 3FRAX 1BOZA 3F0QX 3NU0A 3QFXA 3NXYA 1J3KA 4KYAA 4Q67A 1SEJA 2HM9A 3FQVA 4KD7A 1IA1A 2FZJA 1MVSA 1DYJA 3QG2A 3CLBA 4PTJA 1D1GA 1RA2A 4OR7A 4H98A 4P3RA 4KY8A 3IRNA 1RX2A 3IA4A 2DRCA 2W9SA 4ELBA 3I8AX 2BLAA 3K74A 3SGYA 1M78A 1MVTA 3FQZA 1IA2A 1DDSA 1CZ3A 2OBCA 1DYIA 1HFRA 3KY8A 5DFRA 1DHJA 4M2XA 5HVEA 4EIGA 1DRHA 3LG4A 4XT5A 4NX6A 2XW7A 5E8QA 1J3JA 3GHVA 2W3WA 2D5NA 2W9TA 3ZPGA 3QLXA 1DR2A 8DFRA 4I13A 3KJRA 4XT4A 1AOEA 2JYBA 3FYVX 4DP3A 3NZDA 1U72A 4QI9A 3NXRA 2HQPA 3INVA 3D80A 1YHOA 3SR5X 1M7AA 3HBBA 3JVXA 2INQA 3TQ8A 3L3RA 4XE6X 1TDRA 3KJSA 1DG7A 1QZFA 3JWMA 3EELA 3JW5A 1DISA 3JW3A 2W9HA 2C2TA 2FZIA 3S3VA 3TD8A 5U26A 3NZBX 4DPHA 3QLSA 1DHFA 3NXVA 4XECX 4DFRA 1RA1A 1M79A 1RA3A 2P4GA 4IXGX 4X5GA 2HXVA 3GHCA 4LAGX 4QLEA 2C2SA 1LUDA 1RG7A 4M6JA 1DR5A 1DIUA 1DR3A 4Q0DA 3SRUX 3OAFA 3FL8A 1E26A 2CIGA 3TQ9A 3SRRX 5JA3A 1DRBA 1RX4A 2O7PA 3SRSX 4QJZD 3ROAA 5ECXA 1KMSA 3I3RA 1RC4A 4M7VA 3EEJA 4H97A 4LEKX 3IA5A 1RH3A 4KM2A 4KFJA 2W9GA 3TQBA 1KLKA 2BLBA 3K2HA 2ANOA 1AO8A 2W3MA 5HUIA 4PDJA 3F91A 1KMVA 4H96A 3QYOA 1VDRA 4LAEX 3SRWX 3QYLA 4KLXA 4XRBA 3CSEA 3FQ0A 4Q6AA 3JWKA 1RX1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HA7 A;  2LF1 A;  1VJ3 A;  1LY4 A;  5HQY A;  1DHI A;  5U27 A;  5HT4 A;  2H2Q A;  3EIG A;  3RG9 A;  4HOE A;  4GH8 A;  1S3U A;  4QHV A;  3FY8 X;  4X5F A;  3NXX A;  3IRM A;  3S9U A;  2G6V A;  2ANQ A;  1JOM A;  5ECC A;  4HA9 A;  2W3V A;  1RX3 A;  2CD2 A;  2L28 A;  5FDA A;  3NTZ A;  4IXF X;  4HOG A;  4QLG A;  4FGH A;  3DAT A;  3QLR A;  3S7A A;  3QL3 A;  1DR7 A;  1DG5 A;  1DRE A;  2FZH A;  3DAU A;  1PD8 A;  1PD9 A;  1JUV A;  4EIZ A;  4ELH A;  1LY3 A;  3K45 A;  3SH2 A;  5HQZ A;  3DRC A;  3E0B A;  1RF7 A;  1DLR A;  5HF2 X;  3ZPC A;  3DG8 A;  3FRB X;  4X5J A;  1RB3 A;  4IXE D;  4P3Q A;  4QLF A;  7DFR A;  4KNE A;  3F0B X;  2AZN A;  3DL6 A;  3FQC A;  3NZ9 X;  4ELE A;  3UM5 A;  2BL9 A;  5HF0 X;  1DRF A;  1RB2 A;  1RX9 A;  1U70 A;  2BLC A;  1DR4 A;  3FQF A;  3FY9 X;  4ELG A;  4KJK A;  4FGG A;  5HSU A;  1ZDR A;  3SA1 A;  4X5I A;  2GD9 A;  4PTH A;  3SQY X;  3N0H A;  1IA3 A;  3F0U X;  1DAJ A;  1DDR A;  3QGT A;  1RA8 A;  3CD2 A;  3IX9 A;  3JWF A;  3TQA A;  4KJL A;  4PSY A;  3F8Z A;  3FL9 A;  1DG8 A;  1OHK A;  2W3B A;  4DPD A;  4ECK A;  3Q1H A;  1DR6 A;  3F8Y A;  5CCC A;  1JOL A;  1OHJ A;  1HFQ A;  3DGA A;  4XT7 A;  3NXO A;  4EJ1 A;  3QL0 A;  3DFR A;  3OCH A;  4KM0 A;  3DL5 A;  3FQO A;  2D0K A;  2KGK A;  4KL9 A;  4QJC A;  3NZA X;  1J3I A;  3QLZ A;  4RGC A;  1RX6 A;  3RO9 A;  2ITH A;  3FYW X;  2B3Z A;  4NX7 A;  3F0V X;  1S3Y A;  2ZZA A;  1HFP A;  4PST A;  3K47 A;  1RX5 A;  4M7U A;  4XT6 A;  4X5H A;  3D84 X;  3JSU A;  4KY4 A;  1RX8 A;  3R33 A;  1S3V A;  1DRA A;  3NRR A;  1DYH A;  3KGY A;  4G95 A;  3IRO A;  4ELF A;  3VCO A;  1PDB A;  3JTW A;  4LAH X;  5DXV A;  4M6L A;  4XT8 A;  3NZ6 X;  5HPB A;  3UM8 A;  4KAK A;  1RA9 A;  1RE7 A;  3GI2 A;  5HI6 A;  4HOF A;  3CL9 A;  3EEK A;  3SA2 A;  3F0X X;  5HVB A;  3M09 A;  3KFY A;  4M6K A;  4TU5 X;  4KBN A;  3SAI A;  3FRE X;  3GHW A;  3QLW A;  3GYF A;  2OIP A;  4P68 A;  5EAJ A;  6DFR A;  4FHB A;  4EIL A;  3FRD X;  4OSG A;  4PSS A;  1RX7 A;  5JG0 X;  3HJ3 A;  1CD2 A;  3FS6 A;  4CD2 A;  3NXT A;  4DDR A;  1DYR A;  4G3M A;  5HSR A;  3M08 A;  1DLS A;  5CC9 A;  2DHF A;  1IA4 A;  2QK8 A;  1DF7 A;  4KJJ A;  4Q0E A;  4KEB A;  3NZC X;  3SRQ X;  4P66 A;  1BZF A;  2W3A A;  3QLY A;  3F0S X;  3FRF X;  4G8Z X;  1AI9 A;  1RD7 A;  4H95 A;  1DR1 A;  5HT5 A;  3UM6 A;  1U71 A;  3JWC A;  4I1N A;  3EEM A;  1S3W A;  3EX8 A;  3FRA X;  1BOZ A;  3F0Q X;  3NU0 A;  3QFX A;  3NXY A;  1J3K A;  4KYA A;  4Q67 A;  1SEJ A;  2HM9 A;  3FQV A;  4KD7 A;  1IA1 A;  2FZJ A;  1MVS A;  1DYJ A;  3QG2 A;  3CLB A;  4PTJ A;  1D1G A;  1RA2 A;  4OR7 A;  4H98 A;  4P3R A;  4KY8 A;  3IRN A;  1RX2 A;  3IA4 A;  2DRC A;  2W9S A;  4ELB A;  3I8A X;  2BLA A;  3K74 A;  3SGY A;  1M78 A;  1MVT A;  3FQZ A;  1IA2 A;  1DDS A;  1CZ3 A;  2OBC A;  1DYI A;  1HFR A;  3KY8 A;  5DFR A;  1DHJ A;  4M2X A;  5HVE A;  4EIG A;  1DRH A;  3LG4 A;  4XT5 A;  4NX6 A;  2XW7 A;  5E8Q A;  1J3J A;  3GHV A;  2W3W A;  2D5N A;  2W9T A;  3ZPG A;  3QLX A;  1DR2 A;  8DFR A;  4I13 A;  3KJR A;  4XT4 A;  1AOE A;  2JYB A;  3FYV X;  4DP3 A;  3NZD A;  1U72 A;  4QI9 A;  3NXR A;  2HQP A;  3INV A;  3D80 A;  1YHO A;  3SR5 X;  1M7A A;  3HBB A;  3JVX A;  2INQ A;  3TQ8 A;  3L3R A;  4XE6 X;  1TDR A;  3KJS A;  1DG7 A;  1QZF A;  3JWM A;  3EEL A;  3JW5 A;  1DIS A;  3JW3 A;  2W9H A;  2C2T A;  2FZI A;  3S3V A;  3TD8 A;  5U26 A;  3NZB X;  4DPH A;  3QLS A;  1DHF A;  3NXV A;  4XEC X;  4DFR A;  1RA1 A;  1M79 A;  1RA3 A;  2P4G A;  4IXG X;  4X5G A;  2HXV A;  3GHC A;  4LAG X;  4QLE A;  2C2S A;  1LUD A;  1RG7 A;  4M6J A;  1DR5 A;  1DIU A;  1DR3 A;  4Q0D A;  3SRU X;  3OAF A;  3FL8 A;  1E26 A;  2CIG A;  3TQ9 A;  3SRR X;  5JA3 A;  1DRB A;  1RX4 A;  2O7P A;  3SRS X;  4QJZ D;  3ROA A;  5ECX A;  1KMS A;  3I3R A;  1RC4 A;  4M7V A;  3EEJ A;  4H97 A;  4LEK X;  3IA5 A;  1RH3 A;  4KM2 A;  4KFJ A;  2W9G A;  3TQB A;  1KLK A;  2BLB A;  3K2H A;  2ANO A;  1AO8 A;  2W3M A;  5HUI A;  4PDJ A;  3F91 A;  1KMV A;  4H96 A;  3QYO A;  1VDR A;  4LAE X;  3SRW X;  3QYL A;  4KLX A;  4XRB A;  3CSE A;  3FQ0 A;  4Q6A A;  3JWK A;  1RX1 A; 
#chains in the Genus database with same CATH topology
 4HA7 A;  2LF1 A;  1VJ3 A;  1LY4 A;  5HQY A;  1DHI A;  5U27 A;  5HT4 A;  2H2Q A;  3EIG A;  3RG9 A;  4HOE A;  4GH8 A;  1S3U A;  4QHV A;  3FY8 X;  4X5F A;  3NXX A;  3IRM A;  3S9U A;  2G6V A;  2ANQ A;  1JOM A;  5ECC A;  4HA9 A;  2W3V A;  1RX3 A;  2CD2 A;  2L28 A;  5FDA A;  3NTZ A;  4IXF X;  4HOG A;  4QLG A;  4FGH A;  3DAT A;  3QLR A;  3S7A A;  3QL3 A;  1DR7 A;  1DG5 A;  1DRE A;  2FZH A;  3DAU A;  1PD8 A;  1PD9 A;  1JUV A;  4EIZ A;  4ELH A;  1LY3 A;  3K45 A;  3SH2 A;  5HQZ A;  3DRC A;  3E0B A;  1RF7 A;  1DLR A;  5HF2 X;  3ZPC A;  3DG8 A;  3FRB X;  4X5J A;  1RB3 A;  4IXE D;  4P3Q A;  4QLF A;  7DFR A;  4KNE A;  3F0B X;  2AZN A;  3DL6 A;  3FQC A;  3NZ9 X;  4ELE A;  3UM5 A;  2BL9 A;  5HF0 X;  1DRF A;  1RB2 A;  1RX9 A;  1U70 A;  2BLC A;  1DR4 A;  3FQF A;  3FY9 X;  4ELG A;  4KJK A;  4FGG A;  5HSU A;  1ZDR A;  3SA1 A;  4X5I A;  2GD9 A;  4PTH A;  3SQY X;  3N0H A;  1IA3 A;  3F0U X;  1DAJ A;  1DDR A;  3QGT A;  1RA8 A;  3CD2 A;  3IX9 A;  3JWF A;  3TQA A;  4KJL A;  4PSY A;  3F8Z A;  3FL9 A;  1DG8 A;  1OHK A;  2W3B A;  4DPD A;  4ECK A;  3Q1H A;  1DR6 A;  3F8Y A;  5CCC A;  1JOL A;  1OHJ A;  1HFQ A;  3DGA A;  4XT7 A;  3NXO A;  4EJ1 A;  3QL0 A;  3DFR A;  3OCH A;  4KM0 A;  3DL5 A;  3FQO A;  2D0K A;  2KGK A;  4KL9 A;  4QJC A;  3NZA X;  1J3I A;  3QLZ A;  4RGC A;  1RX6 A;  3RO9 A;  2ITH A;  3FYW X;  2B3Z A;  4NX7 A;  3F0V X;  1S3Y A;  2ZZA A;  1HFP A;  4PST A;  3K47 A;  1RX5 A;  4M7U A;  4XT6 A;  4X5H A;  3D84 X;  3JSU A;  4KY4 A;  1RX8 A;  3R33 A;  1S3V A;  1DRA A;  3NRR A;  1DYH A;  3KGY A;  4G95 A;  3IRO A;  4ELF A;  3VCO A;  1PDB A;  3JTW A;  4LAH X;  5DXV A;  4M6L A;  4XT8 A;  3NZ6 X;  5HPB A;  3UM8 A;  4KAK A;  1RA9 A;  1RE7 A;  3GI2 A;  5HI6 A;  4HOF A;  3CL9 A;  3EEK A;  3SA2 A;  3F0X X;  5HVB A;  3M09 A;  3KFY A;  4M6K A;  4TU5 X;  4KBN A;  3SAI A;  3FRE X;  3GHW A;  3QLW A;  3GYF A;  2OIP A;  4P68 A;  5EAJ A;  6DFR A;  4FHB A;  4EIL A;  3FRD X;  4OSG A;  4PSS A;  1RX7 A;  5JG0 X;  3HJ3 A;  1CD2 A;  3FS6 A;  4CD2 A;  3NXT A;  4DDR A;  1DYR A;  4G3M A;  5HSR A;  3M08 A;  1DLS A;  5CC9 A;  2DHF A;  1IA4 A;  2QK8 A;  1DF7 A;  4KJJ A;  4Q0E A;  4KEB A;  3NZC X;  3SRQ X;  4P66 A;  1BZF A;  2W3A A;  3QLY A;  3F0S X;  3FRF X;  4G8Z X;  1AI9 A;  1RD7 A;  4H95 A;  1DR1 A;  5HT5 A;  3UM6 A;  1U71 A;  3JWC A;  4I1N A;  3EEM A;  1S3W A;  3EX8 A;  3FRA X;  1BOZ A;  3F0Q X;  3NU0 A;  3QFX A;  3NXY A;  1J3K A;  4KYA A;  4Q67 A;  1SEJ A;  2HM9 A;  3FQV A;  4KD7 A;  1IA1 A;  2FZJ A;  1MVS A;  1DYJ A;  3QG2 A;  3CLB A;  4PTJ A;  1D1G A;  1RA2 A;  4OR7 A;  4H98 A;  4P3R A;  4KY8 A;  3IRN A;  1RX2 A;  3IA4 A;  2DRC A;  2W9S A;  4ELB A;  3I8A X;  2BLA A;  3K74 A;  3SGY A;  1M78 A;  1MVT A;  3FQZ A;  1IA2 A;  1DDS A;  1CZ3 A;  2OBC A;  1DYI A;  1HFR A;  3KY8 A;  5DFR A;  1DHJ A;  4M2X A;  5HVE A;  4EIG A;  1DRH A;  3LG4 A;  4XT5 A;  4NX6 A;  2XW7 A;  5E8Q A;  1J3J A;  3GHV A;  2W3W A;  2D5N A;  2W9T A;  3ZPG A;  3QLX A;  1DR2 A;  8DFR A;  4I13 A;  3KJR A;  4XT4 A;  1AOE A;  2JYB A;  3FYV X;  4DP3 A;  3NZD A;  1U72 A;  4QI9 A;  3NXR A;  2HQP A;  3INV A;  3D80 A;  1YHO A;  3SR5 X;  1M7A A;  3HBB A;  3JVX A;  2INQ A;  3TQ8 A;  3L3R A;  4XE6 X;  1TDR A;  3KJS A;  1DG7 A;  1QZF A;  3JWM A;  3EEL A;  3JW5 A;  1DIS A;  3JW3 A;  2W9H A;  2C2T A;  2FZI A;  3S3V A;  3TD8 A;  5U26 A;  3NZB X;  4DPH A;  3QLS A;  1DHF A;  3NXV A;  4XEC X;  4DFR A;  1RA1 A;  1M79 A;  1RA3 A;  2P4G A;  4IXG X;  4X5G A;  2HXV A;  3GHC A;  4LAG X;  4QLE A;  2C2S A;  1LUD A;  1RG7 A;  4M6J A;  1DR5 A;  1DIU A;  1DR3 A;  4Q0D A;  3SRU X;  3OAF A;  3FL8 A;  1E26 A;  2CIG A;  3TQ9 A;  3SRR X;  5JA3 A;  1DRB A;  1RX4 A;  2O7P A;  3SRS X;  4QJZ D;  3ROA A;  5ECX A;  1KMS A;  3I3R A;  1RC4 A;  4M7V A;  3EEJ A;  4H97 A;  4LEK X;  3IA5 A;  1RH3 A;  4KM2 A;  4KFJ A;  2W9G A;  3TQB A;  1KLK A;  2BLB A;  3K2H A;  2ANO A;  1AO8 A;  2W3M A;  5HUI A;  4PDJ A;  3F91 A;  1KMV A;  4H96 A;  3QYO A;  1VDR A;  4LAE X;  3SRW X;  3QYL A;  4KLX A;  4XRB A;  3CSE A;  3FQ0 A;  4Q6A A;  3JWK A;  1RX1 A; 
#chains in the Genus database with same CATH homology
 4HA7 A;  2LF1 A;  1VJ3 A;  1LY4 A;  5HQY A;  1DHI A;  5U27 A;  5HT4 A;  2H2Q A;  3EIG A;  3RG9 A;  4HOE A;  4GH8 A;  1S3U A;  4QHV A;  3FY8 X;  4X5F A;  3NXX A;  3IRM A;  3S9U A;  2G6V A;  2ANQ A;  1JOM A;  5ECC A;  4HA9 A;  2W3V A;  1RX3 A;  2CD2 A;  2L28 A;  5FDA A;  3NTZ A;  4IXF X;  4HOG A;  4QLG A;  4FGH A;  3DAT A;  3QLR A;  3S7A A;  3QL3 A;  1DR7 A;  1DG5 A;  1DRE A;  2FZH A;  3DAU A;  1PD8 A;  1PD9 A;  1JUV A;  4EIZ A;  4ELH A;  1LY3 A;  3K45 A;  3SH2 A;  5HQZ A;  3DRC A;  3E0B A;  1RF7 A;  1DLR A;  5HF2 X;  3ZPC A;  3DG8 A;  3FRB X;  4X5J A;  1RB3 A;  4IXE D;  4P3Q A;  4QLF A;  7DFR A;  4KNE A;  3F0B X;  2AZN A;  3DL6 A;  3FQC A;  3NZ9 X;  4ELE A;  3UM5 A;  2BL9 A;  5HF0 X;  1DRF A;  1RB2 A;  1RX9 A;  1U70 A;  2BLC A;  1DR4 A;  3FQF A;  3FY9 X;  4ELG A;  4KJK A;  4FGG A;  5HSU A;  1ZDR A;  3SA1 A;  4X5I A;  2GD9 A;  4PTH A;  3SQY X;  3N0H A;  1IA3 A;  3F0U X;  1DAJ A;  1DDR A;  3QGT A;  1RA8 A;  3CD2 A;  3IX9 A;  3JWF A;  3TQA A;  4KJL A;  4PSY A;  3F8Z A;  3FL9 A;  1DG8 A;  1OHK A;  2W3B A;  4DPD A;  4ECK A;  3Q1H A;  1DR6 A;  3F8Y A;  5CCC A;  1JOL A;  1OHJ A;  1HFQ A;  3DGA A;  4XT7 A;  3NXO A;  4EJ1 A;  3QL0 A;  3DFR A;  3OCH A;  4KM0 A;  3DL5 A;  3FQO A;  2D0K A;  2KGK A;  4KL9 A;  4QJC A;  3NZA X;  1J3I A;  3QLZ A;  4RGC A;  1RX6 A;  3RO9 A;  2ITH A;  3FYW X;  2B3Z A;  4NX7 A;  3F0V X;  1S3Y A;  2ZZA A;  1HFP A;  4PST A;  3K47 A;  1RX5 A;  4M7U A;  4XT6 A;  4X5H A;  3D84 X;  3JSU A;  4KY4 A;  1RX8 A;  3R33 A;  1S3V A;  1DRA A;  3NRR A;  1DYH A;  3KGY A;  4G95 A;  3IRO A;  4ELF A;  3VCO A;  1PDB A;  3JTW A;  4LAH X;  5DXV A;  4M6L A;  4XT8 A;  3NZ6 X;  5HPB A;  3UM8 A;  4KAK A;  1RA9 A;  1RE7 A;  3GI2 A;  5HI6 A;  4HOF A;  3CL9 A;  3EEK A;  3SA2 A;  3F0X X;  5HVB A;  3M09 A;  3KFY A;  4M6K A;  4TU5 X;  4KBN A;  3SAI A;  3FRE X;  3GHW A;  3QLW A;  3GYF A;  2OIP A;  4P68 A;  5EAJ A;  6DFR A;  4FHB A;  4EIL A;  3FRD X;  4OSG A;  4PSS A;  1RX7 A;  5JG0 X;  3HJ3 A;  1CD2 A;  3FS6 A;  4CD2 A;  3NXT A;  4DDR A;  1DYR A;  4G3M A;  5HSR A;  3M08 A;  1DLS A;  5CC9 A;  2DHF A;  1IA4 A;  2QK8 A;  1DF7 A;  4KJJ A;  4Q0E A;  4KEB A;  3NZC X;  3SRQ X;  4P66 A;  1BZF A;  2W3A A;  3QLY A;  3F0S X;  3FRF X;  4G8Z X;  1AI9 A;  1RD7 A;  4H95 A;  1DR1 A;  5HT5 A;  3UM6 A;  1U71 A;  3JWC A;  4I1N A;  3EEM A;  1S3W A;  3EX8 A;  3FRA X;  1BOZ A;  3F0Q X;  3NU0 A;  3QFX A;  3NXY A;  1J3K A;  4KYA A;  4Q67 A;  1SEJ A;  2HM9 A;  3FQV A;  4KD7 A;  1IA1 A;  2FZJ A;  1MVS A;  1DYJ A;  3QG2 A;  3CLB A;  4PTJ A;  1D1G A;  1RA2 A;  4OR7 A;  4H98 A;  4P3R A;  4KY8 A;  3IRN A;  1RX2 A;  3IA4 A;  2DRC A;  2W9S A;  4ELB A;  3I8A X;  2BLA A;  3K74 A;  3SGY A;  1M78 A;  1MVT A;  3FQZ A;  1IA2 A;  1DDS A;  1CZ3 A;  2OBC A;  1DYI A;  1HFR A;  3KY8 A;  5DFR A;  1DHJ A;  4M2X A;  5HVE A;  4EIG A;  1DRH A;  3LG4 A;  4XT5 A;  4NX6 A;  2XW7 A;  5E8Q A;  1J3J A;  3GHV A;  2W3W A;  2D5N A;  2W9T A;  3ZPG A;  3QLX A;  1DR2 A;  8DFR A;  4I13 A;  3KJR A;  4XT4 A;  1AOE A;  2JYB A;  3FYV X;  4DP3 A;  3NZD A;  1U72 A;  4QI9 A;  3NXR A;  2HQP A;  3INV A;  3D80 A;  1YHO A;  3SR5 X;  1M7A A;  3HBB A;  3JVX A;  2INQ A;  3TQ8 A;  3L3R A;  4XE6 X;  1TDR A;  3KJS A;  1DG7 A;  1QZF A;  3JWM A;  3EEL A;  3JW5 A;  1DIS A;  3JW3 A;  2W9H A;  2C2T A;  2FZI A;  3S3V A;  3TD8 A;  5U26 A;  3NZB X;  4DPH A;  3QLS A;  1DHF A;  3NXV A;  4XEC X;  4DFR A;  1RA1 A;  1M79 A;  1RA3 A;  2P4G A;  4IXG X;  4X5G A;  2HXV A;  3GHC A;  4LAG X;  4QLE A;  2C2S A;  1LUD A;  1RG7 A;  4M6J A;  1DR5 A;  1DIU A;  1DR3 A;  4Q0D A;  3SRU X;  3OAF A;  3FL8 A;  1E26 A;  2CIG A;  3TQ9 A;  3SRR X;  5JA3 A;  1DRB A;  1RX4 A;  2O7P A;  3SRS X;  4QJZ D;  3ROA A;  5ECX A;  1KMS A;  3I3R A;  1RC4 A;  4M7V A;  3EEJ A;  4H97 A;  4LEK X;  3IA5 A;  1RH3 A;  4KM2 A;  4KFJ A;  2W9G A;  3TQB A;  1KLK A;  2BLB A;  3K2H A;  2ANO A;  1AO8 A;  2W3M A;  5HUI A;  4PDJ A;  3F91 A;  1KMV A;  4H96 A;  3QYO A;  1VDR A;  4LAE X;  3SRW X;  3QYL A;  4KLX A;  4XRB A;  3CSE A;  3FQ0 A;  4Q6A A;  3JWK A;  1RX1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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