3EEJA

Candida glabrata dihydrofolate reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-phenylphenyl)prop-1-ynyl]-6-methylpyrimidine(ucp111d) and nadph
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
225
structure length
225
Chain Sequence
KVPVVGIVAALLPEMGIGFQGNLPWRLAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQKFRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGEIYRQSMDLADHWLITKIMPLPETTIPQMDTFLQKQELEQRFYDNSDKLVDFLPSSIQLEGRLTSQEWNGELVKGLPVQEKGYQFYFTLYTKKLEHHHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Candida glabrata
molecule keywords Dihydrofolate reductase
total genus 61
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3eejA00
1BZFA 6DFRA 3FYWX 2ANQA 2W9HA 3D84X 3CSEA 1AOEA 3GI2A 3IA5A 4XT7A 3LG4A 1D1GA 1DHFA 2BL9A 1AI9A 4CD2A 1DRAA 3TQ9A 1DG5A 4X5FA 1DYRA 1HFPA 4KL9A 2W3VA 1KMVA 2O7PA 4FGHA 1J3KA 4XT6A 1IA1A 5HVBA 5HT4A 3IRNA 3DL5A 7DFRA 3OCHA 3NZ9X 4M7VA 1DR6A 4XT4A 3FQ0A 2HQPA 4M6JA 4EILA 4DFRA 1DR7A 4KD7A 4XT8A 3TQAA 3IA4A 3L3RA 4Q67A 4KJLA 1KMSA 1OHJA 3JW3A 3GHCA 2XW7A 1DRBA 4EJ1A 4G3MA 1TDRA 4KEBA 1S3YA 4M7UA 1DR5A 3Q1HA 3EEKA 1CZ3A 4KAKA 5HT5A 3DFRA 3NXRA 1ZDRA 2JYBA 1RE7A 3M08A 4X5JA 1DRFA 3JTWA 4I1NA 4QHVA 2D0KA 4KY4A 1DDSA 3ROAA 3SAIA 2GD9A 3QLRA 4HA9A 4HOFA 3GYFA 3SRQX 3EIGA 4M2XA 4P68A 4X5GA 4KBNA 5HQYA 3QL0A 4IXFX 4H96A 3NRRA 4XE6X 4LAGX 3FRBX 4LAHX 4IXGX 3FY8X 3DAUA 5HF0X 4PTJA 2C2SA 4KYAA 1LY3A 4NX6A 3FRAX 4OR7A 2DRCA 3TQBA 1DLRA 3DRCA 1RX2A 3IRMA 1CD2A 4QLFA 2B3ZA 1RA2A 3CL9A 3SRSX 3EELA 3UM6A 4KM2A 1VDRA 3NZAX 1BOZA 3DL6A 5CC9A 2W3MA 5HPBA 1DYIA 4DP3A 2H2QA 1DREA 4DPHA 3SQYX 1JUVA 4HOGA 3SRWX 1E26A 1RX9A 3KY8A 2DHFA 1RB3A 3F0BX 4QI9A 2C2TA 4OSGA 4TU5X 1RB2A 3JWCA 3FQZA 3EEMA 2FZHA 5ECCA 4KM0A 4HOEA 1PD9A 2HXVA 3SRUX 3R33A 5HSRA 4KLXA 2G6VA 4NX7A 3INVA 3F8ZA 4HA7A 2HM9A 1S3VA 3QL3A 1IA2A 2W9SA 4PDJA 2W9TA 3NXOA 3NXYA 1AO8A 5U26A 1RA9A 1RA3A 3HJ3A 1DYHA 4PSTA 1HFRA 2ANOA 1DLSA 3NZCX 3F91A 4X5IA 1DRHA 2LF1A 2BLBA 3DGAA 5FDAA 3OAFA 4P3QA 2D5NA 3NXTA 4PSYA 3F0QX 1OHKA 5ECXA 3RG9A 4QLEA 1DF7A 2W9GA 3QG2A 2W3AA 1IA4A 4ELGA 3SR5X 3S7AA 1DR4A 4PTHA 4ELBA 3NXXA 4G95A 5E8QA 5HF2X 4M6KA 2W3BA 1M79A 3GHVA 3CLBA 3DATA 3KGYA 1SEJA 4IXED 3E0BA 3JWFA 5HVEA 3NXVA 3TD8A 2FZJA 3UM5A 1DIUA 3JSUA 5DXVA 3F0SX 3FYVX 3NZBX 1DISA 4EIZA 2ITHA 4X5HA 1RX8A 3FL9A 3SRRX 4ELEA 3EX8A 5U27A 3K47A 3S3VA 2AZNA 3SA2A 4KFJA 1J3JA 4XRBA 1DYJA 1DHJA 3CD2A 3F0XX 3SGYA 4QJZD 3F0VX 3QYOA 3FL8A 3KJRA 3NZ6X 1U71A 1RA8A 3FREX 2KGKA 3FQFA 1MVSA 2L28A 4H95A 3VCOA 1YHOA 3D80A 3FRFX 3HBBA 1S3WA 3FY9X 1S3UA 1JOMA 4P66A 3SA1A 3F0UX 3K45A 3FS6A 3IROA 4Q0DA 1RC4A 3ZPCA 3FQVA 3GHWA 5CCCA 8DFRA 2QK8A 4FHBA 3F8YA 1RX7A 4KY8A 3UM8A 3SH2A 3N0HA 1MVTA 2P4GA 1RA1A 3JVXA 1M78A 3KJSA 1RX6A 1DR2A 3KFYA 3NU0A 4G8ZX 1PDBA 5HQZA 3I8AX 3JWKA 4GH8A 4KJKA 1LY4A 1DHIA 2W3WA 1JOLA 1DG8A 4Q0EA 1DAJA 1DDRA 3DG8A 1J3IA 4XECX 1VJ3A 2BLAA 1PD8A 4QLGA 4LAEX 1KLKA 1HFQA 2FZIA 2OIPA 1RX5A 3IX9A 4DPDA 4M6LA 4H98A 3QGTA 2OBCA 3M09A 3NZDA 2CIGA 4I13A 2CD2A 5HUIA 3QLSA 3QLWA 1M7AA 3QYLA 3FRDX 3QFXA 3I3RA 1DG7A 3TQ8A 2BLCA 1RD7A 1RX3A 1RF7A 4ELHA 2INQA 4FGGA 2ZZAA 3JWMA 4RGCA 5DFRA 1LUDA 4PSSA 4DDRA 1DR1A 3EEJA 3NTZA 3QLXA 3ZPGA 3K2HA 5EAJA 4KNEA 3RO9A 5JA3A 1QZFA 3K74A 4QJCA 3FQCA 1U70A 1DR3A 1RH3A 4KJJA 4XT5A 4EIGA 5HSUA 1RX1A 3QLYA 4Q6AA 5HI6A 1RX4A 4ELFA 3QLZA 1RG7A 4P3RA 1IA3A 5JG0X 4H97A 3FQOA 4ECKA 1U72A 3S9UA 3JW5A 4LEKX
chains in the Genus database with same CATH superfamily
1BZFA 6DFRA 3FYWX 2ANQA 2W9HA 3D84X 3CSEA 1AOEA 3GI2A 3IA5A 4XT7A 3LG4A 1D1GA 1DHFA 2BL9A 1AI9A 4CD2A 1DRAA 3TQ9A 1DG5A 4X5FA 1DYRA 1HFPA 4KL9A 2W3VA 1KMVA 2O7PA 4FGHA 1J3KA 4XT6A 1IA1A 5HVBA 5HT4A 3IRNA 3DL5A 7DFRA 3OCHA 3NZ9X 4M7VA 1DR6A 4XT4A 3FQ0A 2HQPA 4M6JA 4EILA 4DFRA 1DR7A 4KD7A 4XT8A 3TQAA 3IA4A 3L3RA 4Q67A 4KJLA 1KMSA 1OHJA 3JW3A 3GHCA 2XW7A 1DRBA 4EJ1A 4G3MA 1TDRA 4KEBA 1S3YA 4M7UA 1DR5A 3Q1HA 3EEKA 1CZ3A 4KAKA 5HT5A 3DFRA 3NXRA 1ZDRA 2JYBA 1RE7A 3M08A 4X5JA 1DRFA 3JTWA 4I1NA 4QHVA 2D0KA 4KY4A 1DDSA 3ROAA 3SAIA 2GD9A 3QLRA 4HA9A 4HOFA 3GYFA 3SRQX 3EIGA 4M2XA 4P68A 4X5GA 4KBNA 5HQYA 3QL0A 4IXFX 4H96A 3NRRA 4XE6X 4LAGX 3FRBX 4LAHX 4IXGX 3FY8X 3DAUA 5HF0X 4PTJA 2C2SA 4KYAA 1LY3A 4NX6A 3FRAX 4OR7A 2DRCA 3TQBA 1DLRA 3DRCA 1RX2A 3IRMA 1CD2A 4QLFA 2B3ZA 1RA2A 3CL9A 3SRSX 3EELA 3UM6A 4KM2A 1VDRA 3NZAX 1BOZA 3DL6A 5CC9A 2W3MA 5HPBA 1DYIA 4DP3A 2H2QA 1DREA 4DPHA 3SQYX 1JUVA 4HOGA 3SRWX 1E26A 1RX9A 3KY8A 2DHFA 1RB3A 3F0BX 4QI9A 2C2TA 4OSGA 4TU5X 1RB2A 3JWCA 3FQZA 3EEMA 2FZHA 5ECCA 4KM0A 4HOEA 1PD9A 2HXVA 3SRUX 3R33A 5HSRA 4KLXA 2G6VA 4NX7A 3INVA 3F8ZA 4HA7A 2HM9A 1S3VA 3QL3A 1IA2A 2W9SA 4PDJA 2W9TA 3NXOA 3NXYA 1AO8A 5U26A 1RA9A 1RA3A 3HJ3A 1DYHA 4PSTA 1HFRA 2ANOA 1DLSA 3NZCX 3F91A 4X5IA 1DRHA 2LF1A 2BLBA 3DGAA 5FDAA 3OAFA 4P3QA 2D5NA 3NXTA 4PSYA 3F0QX 1OHKA 5ECXA 3RG9A 4QLEA 1DF7A 2W9GA 3QG2A 2W3AA 1IA4A 4ELGA 3SR5X 3S7AA 1DR4A 4PTHA 4ELBA 3NXXA 4G95A 5E8QA 5HF2X 4M6KA 2W3BA 1M79A 3GHVA 3CLBA 3DATA 3KGYA 1SEJA 4IXED 3E0BA 3JWFA 5HVEA 3NXVA 3TD8A 2FZJA 3UM5A 1DIUA 3JSUA 5DXVA 3F0SX 3FYVX 3NZBX 1DISA 4EIZA 2ITHA 4X5HA 1RX8A 3FL9A 3SRRX 4ELEA 3EX8A 5U27A 3K47A 3S3VA 2AZNA 3SA2A 4KFJA 1J3JA 4XRBA 1DYJA 1DHJA 3CD2A 3F0XX 3SGYA 4QJZD 3F0VX 3QYOA 3FL8A 3KJRA 3NZ6X 1U71A 1RA8A 3FREX 2KGKA 3FQFA 1MVSA 2L28A 4H95A 3VCOA 1YHOA 3D80A 3FRFX 3HBBA 1S3WA 3FY9X 1S3UA 1JOMA 4P66A 3SA1A 3F0UX 3K45A 3FS6A 3IROA 4Q0DA 1RC4A 3ZPCA 3FQVA 3GHWA 5CCCA 8DFRA 2QK8A 4FHBA 3F8YA 1RX7A 4KY8A 3UM8A 3SH2A 3N0HA 1MVTA 2P4GA 1RA1A 3JVXA 1M78A 3KJSA 1RX6A 1DR2A 3KFYA 3NU0A 4G8ZX 1PDBA 5HQZA 3I8AX 3JWKA 4GH8A 4KJKA 1LY4A 1DHIA 2W3WA 1JOLA 1DG8A 4Q0EA 1DAJA 1DDRA 3DG8A 1J3IA 4XECX 1VJ3A 2BLAA 1PD8A 4QLGA 4LAEX 1KLKA 1HFQA 2FZIA 2OIPA 1RX5A 3IX9A 4DPDA 4M6LA 4H98A 3QGTA 2OBCA 3M09A 3NZDA 2CIGA 4I13A 2CD2A 5HUIA 3QLSA 3QLWA 1M7AA 3QYLA 3FRDX 3QFXA 3I3RA 1DG7A 3TQ8A 2BLCA 1RD7A 1RX3A 1RF7A 4ELHA 2INQA 4FGGA 2ZZAA 3JWMA 4RGCA 5DFRA 1LUDA 4PSSA 4DDRA 1DR1A 3EEJA 3NTZA 3QLXA 3ZPGA 3K2HA 5EAJA 4KNEA 3RO9A 5JA3A 1QZFA 3K74A 4QJCA 3FQCA 1U70A 1DR3A 1RH3A 4KJJA 4XT5A 4EIGA 5HSUA 1RX1A 3QLYA 4Q6AA 5HI6A 1RX4A 4ELFA 3QLZA 1RG7A 4P3RA 1IA3A 5JG0X 4H97A 3FQOA 4ECKA 1U72A 3S9UA 3JW5A 4LEKX
chains in the Genus database with same CATH topology
1BZFA 6DFRA 3FYWX 2ANQA 2W9HA 3D84X 3CSEA 1AOEA 3GI2A 3IA5A 4XT7A 3LG4A 1D1GA 1DHFA 2BL9A 1AI9A 4CD2A 1DRAA 3TQ9A 1DG5A 4X5FA 1DYRA 1HFPA 4KL9A 2W3VA 1KMVA 2O7PA 4FGHA 1J3KA 4XT6A 1IA1A 5HVBA 5HT4A 3IRNA 3DL5A 7DFRA 3OCHA 3NZ9X 4M7VA 1DR6A 4XT4A 3FQ0A 2HQPA 4M6JA 4EILA 4DFRA 1DR7A 4KD7A 4XT8A 3TQAA 3IA4A 3L3RA 4Q67A 4KJLA 1KMSA 1OHJA 3JW3A 3GHCA 2XW7A 1DRBA 4EJ1A 4G3MA 1TDRA 4KEBA 1S3YA 4M7UA 1DR5A 3Q1HA 3EEKA 1CZ3A 4KAKA 5HT5A 3DFRA 3NXRA 1ZDRA 2JYBA 1RE7A 3M08A 4X5JA 1DRFA 3JTWA 4I1NA 4QHVA 2D0KA 4KY4A 1DDSA 3ROAA 3SAIA 2GD9A 3QLRA 4HA9A 4HOFA 3GYFA 3SRQX 3EIGA 4M2XA 4P68A 4X5GA 4KBNA 5HQYA 3QL0A 4IXFX 4H96A 3NRRA 4XE6X 4LAGX 3FRBX 4LAHX 4IXGX 3FY8X 3DAUA 5HF0X 4PTJA 2C2SA 4KYAA 1LY3A 4NX6A 3FRAX 4OR7A 2DRCA 3TQBA 1DLRA 3DRCA 1RX2A 3IRMA 1CD2A 4QLFA 2B3ZA 1RA2A 3CL9A 3SRSX 3EELA 3UM6A 4KM2A 1VDRA 3NZAX 1BOZA 3DL6A 5CC9A 2W3MA 5HPBA 1DYIA 4DP3A 2H2QA 1DREA 4DPHA 3SQYX 1JUVA 4HOGA 3SRWX 1E26A 1RX9A 3KY8A 2DHFA 1RB3A 3F0BX 4QI9A 2C2TA 4OSGA 4TU5X 1RB2A 3JWCA 3FQZA 3EEMA 2FZHA 5ECCA 4KM0A 4HOEA 1PD9A 2HXVA 3SRUX 3R33A 5HSRA 4KLXA 2G6VA 4NX7A 3INVA 3F8ZA 4HA7A 2HM9A 1S3VA 3QL3A 1IA2A 2W9SA 4PDJA 2W9TA 3NXOA 3NXYA 1AO8A 5U26A 1RA9A 1RA3A 3HJ3A 1DYHA 4PSTA 1HFRA 2ANOA 1DLSA 3NZCX 3F91A 4X5IA 1DRHA 2LF1A 2BLBA 3DGAA 5FDAA 3OAFA 4P3QA 2D5NA 3NXTA 4PSYA 3F0QX 1OHKA 5ECXA 3RG9A 4QLEA 1DF7A 2W9GA 3QG2A 2W3AA 1IA4A 4ELGA 3SR5X 3S7AA 1DR4A 4PTHA 4ELBA 3NXXA 4G95A 5E8QA 5HF2X 4M6KA 2W3BA 1M79A 3GHVA 3CLBA 3DATA 3KGYA 1SEJA 4IXED 3E0BA 3JWFA 5HVEA 3NXVA 3TD8A 2FZJA 3UM5A 1DIUA 3JSUA 5DXVA 3F0SX 3FYVX 3NZBX 1DISA 4EIZA 2ITHA 4X5HA 1RX8A 3FL9A 3SRRX 4ELEA 3EX8A 5U27A 3K47A 3S3VA 2AZNA 3SA2A 4KFJA 1J3JA 4XRBA 1DYJA 1DHJA 3CD2A 3F0XX 3SGYA 4QJZD 3F0VX 3QYOA 3FL8A 3KJRA 3NZ6X 1U71A 1RA8A 3FREX 2KGKA 3FQFA 1MVSA 2L28A 4H95A 3VCOA 1YHOA 3D80A 3FRFX 3HBBA 1S3WA 3FY9X 1S3UA 1JOMA 4P66A 3SA1A 3F0UX 3K45A 3FS6A 3IROA 4Q0DA 1RC4A 3ZPCA 3FQVA 3GHWA 5CCCA 8DFRA 2QK8A 4FHBA 3F8YA 1RX7A 4KY8A 3UM8A 3SH2A 3N0HA 1MVTA 2P4GA 1RA1A 3JVXA 1M78A 3KJSA 1RX6A 1DR2A 3KFYA 3NU0A 4G8ZX 1PDBA 5HQZA 3I8AX 3JWKA 4GH8A 4KJKA 1LY4A 1DHIA 2W3WA 1JOLA 1DG8A 4Q0EA 1DAJA 1DDRA 3DG8A 1J3IA 4XECX 1VJ3A 2BLAA 1PD8A 4QLGA 4LAEX 1KLKA 1HFQA 2FZIA 2OIPA 1RX5A 3IX9A 4DPDA 4M6LA 4H98A 3QGTA 2OBCA 3M09A 3NZDA 2CIGA 4I13A 2CD2A 5HUIA 3QLSA 3QLWA 1M7AA 3QYLA 3FRDX 3QFXA 3I3RA 1DG7A 3TQ8A 2BLCA 1RD7A 1RX3A 1RF7A 4ELHA 2INQA 4FGGA 2ZZAA 3JWMA 4RGCA 5DFRA 1LUDA 4PSSA 4DDRA 1DR1A 3EEJA 3NTZA 3QLXA 3ZPGA 3K2HA 5EAJA 4KNEA 3RO9A 5JA3A 1QZFA 3K74A 4QJCA 3FQCA 1U70A 1DR3A 1RH3A 4KJJA 4XT5A 4EIGA 5HSUA 1RX1A 3QLYA 4Q6AA 5HI6A 1RX4A 4ELFA 3QLZA 1RG7A 4P3RA 1IA3A 5JG0X 4H97A 3FQOA 4ECKA 1U72A 3S9UA 3JW5A 4LEKX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BZF A;  6DFR A;  3FYW X;  2ANQ A;  2W9H A;  3D84 X;  3CSE A;  1AOE A;  3GI2 A;  3IA5 A;  4XT7 A;  3LG4 A;  1D1G A;  1DHF A;  2BL9 A;  1AI9 A;  4CD2 A;  1DRA A;  3TQ9 A;  1DG5 A;  4X5F A;  1DYR A;  1HFP A;  4KL9 A;  2W3V A;  1KMV A;  2O7P A;  4FGH A;  1J3K A;  4XT6 A;  1IA1 A;  5HVB A;  5HT4 A;  3IRN A;  3DL5 A;  7DFR A;  3OCH A;  3NZ9 X;  4M7V A;  1DR6 A;  4XT4 A;  3FQ0 A;  2HQP A;  4M6J A;  4EIL A;  4DFR A;  1DR7 A;  4KD7 A;  4XT8 A;  3TQA A;  3IA4 A;  3L3R A;  4Q67 A;  4KJL A;  1KMS A;  1OHJ A;  3JW3 A;  3GHC A;  2XW7 A;  1DRB A;  4EJ1 A;  4G3M A;  1TDR A;  4KEB A;  1S3Y A;  4M7U A;  1DR5 A;  3Q1H A;  3EEK A;  1CZ3 A;  4KAK A;  5HT5 A;  3DFR A;  3NXR A;  1ZDR A;  2JYB A;  1RE7 A;  3M08 A;  4X5J A;  1DRF A;  3JTW A;  4I1N A;  4QHV A;  2D0K A;  4KY4 A;  1DDS A;  3ROA A;  3SAI A;  2GD9 A;  3QLR A;  4HA9 A;  4HOF A;  3GYF A;  3SRQ X;  3EIG A;  4M2X A;  4P68 A;  4X5G A;  4KBN A;  5HQY A;  3QL0 A;  4IXF X;  4H96 A;  3NRR A;  4XE6 X;  4LAG X;  3FRB X;  4LAH X;  4IXG X;  3FY8 X;  3DAU A;  5HF0 X;  4PTJ A;  2C2S A;  4KYA A;  1LY3 A;  4NX6 A;  3FRA X;  4OR7 A;  2DRC A;  3TQB A;  1DLR A;  3DRC A;  1RX2 A;  3IRM A;  1CD2 A;  4QLF A;  2B3Z A;  1RA2 A;  3CL9 A;  3SRS X;  3EEL A;  3UM6 A;  4KM2 A;  1VDR A;  3NZA X;  1BOZ A;  3DL6 A;  5CC9 A;  2W3M A;  5HPB A;  1DYI A;  4DP3 A;  2H2Q A;  1DRE A;  4DPH A;  3SQY X;  1JUV A;  4HOG A;  3SRW X;  1E26 A;  1RX9 A;  3KY8 A;  2DHF A;  1RB3 A;  3F0B X;  4QI9 A;  2C2T A;  4OSG A;  4TU5 X;  1RB2 A;  3JWC A;  3FQZ A;  3EEM A;  2FZH A;  5ECC A;  4KM0 A;  4HOE A;  1PD9 A;  2HXV A;  3SRU X;  3R33 A;  5HSR A;  4KLX A;  2G6V A;  4NX7 A;  3INV A;  3F8Z A;  4HA7 A;  2HM9 A;  1S3V A;  3QL3 A;  1IA2 A;  2W9S A;  4PDJ A;  2W9T A;  3NXO A;  3NXY A;  1AO8 A;  5U26 A;  1RA9 A;  1RA3 A;  3HJ3 A;  1DYH A;  4PST A;  1HFR A;  2ANO A;  1DLS A;  3NZC X;  3F91 A;  4X5I A;  1DRH A;  2LF1 A;  2BLB A;  3DGA A;  5FDA A;  3OAF A;  4P3Q A;  2D5N A;  3NXT A;  4PSY A;  3F0Q X;  1OHK A;  5ECX A;  3RG9 A;  4QLE A;  1DF7 A;  2W9G A;  3QG2 A;  2W3A A;  1IA4 A;  4ELG A;  3SR5 X;  3S7A A;  1DR4 A;  4PTH A;  4ELB A;  3NXX A;  4G95 A;  5E8Q A;  5HF2 X;  4M6K A;  2W3B A;  1M79 A;  3GHV A;  3CLB A;  3DAT A;  3KGY A;  1SEJ A;  4IXE D;  3E0B A;  3JWF A;  5HVE A;  3NXV A;  3TD8 A;  2FZJ A;  3UM5 A;  1DIU A;  3JSU A;  5DXV A;  3F0S X;  3FYV X;  3NZB X;  1DIS A;  4EIZ A;  2ITH A;  4X5H A;  1RX8 A;  3FL9 A;  3SRR X;  4ELE A;  3EX8 A;  5U27 A;  3K47 A;  3S3V A;  2AZN A;  3SA2 A;  4KFJ A;  1J3J A;  4XRB A;  1DYJ A;  1DHJ A;  3CD2 A;  3F0X X;  3SGY A;  4QJZ D;  3F0V X;  3QYO A;  3FL8 A;  3KJR A;  3NZ6 X;  1U71 A;  1RA8 A;  3FRE X;  2KGK A;  3FQF A;  1MVS A;  2L28 A;  4H95 A;  3VCO A;  1YHO A;  3D80 A;  3FRF X;  3HBB A;  1S3W A;  3FY9 X;  1S3U A;  1JOM A;  4P66 A;  3SA1 A;  3F0U X;  3K45 A;  3FS6 A;  3IRO A;  4Q0D A;  1RC4 A;  3ZPC A;  3FQV A;  3GHW A;  5CCC A;  8DFR A;  2QK8 A;  4FHB A;  3F8Y A;  1RX7 A;  4KY8 A;  3UM8 A;  3SH2 A;  3N0H A;  1MVT A;  2P4G A;  1RA1 A;  3JVX A;  1M78 A;  3KJS A;  1RX6 A;  1DR2 A;  3KFY A;  3NU0 A;  4G8Z X;  1PDB A;  5HQZ A;  3I8A X;  3JWK A;  4GH8 A;  4KJK A;  1LY4 A;  1DHI A;  2W3W A;  1JOL A;  1DG8 A;  4Q0E A;  1DAJ A;  1DDR A;  3DG8 A;  1J3I A;  4XEC X;  1VJ3 A;  2BLA A;  1PD8 A;  4QLG A;  4LAE X;  1KLK A;  1HFQ A;  2FZI A;  2OIP A;  1RX5 A;  3IX9 A;  4DPD A;  4M6L A;  4H98 A;  3QGT A;  2OBC A;  3M09 A;  3NZD A;  2CIG A;  4I13 A;  2CD2 A;  5HUI A;  3QLS A;  3QLW A;  1M7A A;  3QYL A;  3FRD X;  3QFX A;  3I3R A;  1DG7 A;  3TQ8 A;  2BLC A;  1RD7 A;  1RX3 A;  1RF7 A;  4ELH A;  2INQ A;  4FGG A;  2ZZA A;  3JWM A;  4RGC A;  5DFR A;  1LUD A;  4PSS A;  4DDR A;  1DR1 A;  3EEJ A;  3NTZ A;  3QLX A;  3ZPG A;  3K2H A;  5EAJ A;  4KNE A;  3RO9 A;  5JA3 A;  1QZF A;  3K74 A;  4QJC A;  3FQC A;  1U70 A;  1DR3 A;  1RH3 A;  4KJJ A;  4XT5 A;  4EIG A;  5HSU A;  1RX1 A;  3QLY A;  4Q6A A;  5HI6 A;  1RX4 A;  4ELF A;  3QLZ A;  1RG7 A;  4P3R A;  1IA3 A;  5JG0 X;  4H97 A;  3FQO A;  4ECK A;  1U72 A;  3S9U A;  3JW5 A;  4LEK X; 
#chains in the Genus database with same CATH topology
 1BZF A;  6DFR A;  3FYW X;  2ANQ A;  2W9H A;  3D84 X;  3CSE A;  1AOE A;  3GI2 A;  3IA5 A;  4XT7 A;  3LG4 A;  1D1G A;  1DHF A;  2BL9 A;  1AI9 A;  4CD2 A;  1DRA A;  3TQ9 A;  1DG5 A;  4X5F A;  1DYR A;  1HFP A;  4KL9 A;  2W3V A;  1KMV A;  2O7P A;  4FGH A;  1J3K A;  4XT6 A;  1IA1 A;  5HVB A;  5HT4 A;  3IRN A;  3DL5 A;  7DFR A;  3OCH A;  3NZ9 X;  4M7V A;  1DR6 A;  4XT4 A;  3FQ0 A;  2HQP A;  4M6J A;  4EIL A;  4DFR A;  1DR7 A;  4KD7 A;  4XT8 A;  3TQA A;  3IA4 A;  3L3R A;  4Q67 A;  4KJL A;  1KMS A;  1OHJ A;  3JW3 A;  3GHC A;  2XW7 A;  1DRB A;  4EJ1 A;  4G3M A;  1TDR A;  4KEB A;  1S3Y A;  4M7U A;  1DR5 A;  3Q1H A;  3EEK A;  1CZ3 A;  4KAK A;  5HT5 A;  3DFR A;  3NXR A;  1ZDR A;  2JYB A;  1RE7 A;  3M08 A;  4X5J A;  1DRF A;  3JTW A;  4I1N A;  4QHV A;  2D0K A;  4KY4 A;  1DDS A;  3ROA A;  3SAI A;  2GD9 A;  3QLR A;  4HA9 A;  4HOF A;  3GYF A;  3SRQ X;  3EIG A;  4M2X A;  4P68 A;  4X5G A;  4KBN A;  5HQY A;  3QL0 A;  4IXF X;  4H96 A;  3NRR A;  4XE6 X;  4LAG X;  3FRB X;  4LAH X;  4IXG X;  3FY8 X;  3DAU A;  5HF0 X;  4PTJ A;  2C2S A;  4KYA A;  1LY3 A;  4NX6 A;  3FRA X;  4OR7 A;  2DRC A;  3TQB A;  1DLR A;  3DRC A;  1RX2 A;  3IRM A;  1CD2 A;  4QLF A;  2B3Z A;  1RA2 A;  3CL9 A;  3SRS X;  3EEL A;  3UM6 A;  4KM2 A;  1VDR A;  3NZA X;  1BOZ A;  3DL6 A;  5CC9 A;  2W3M A;  5HPB A;  1DYI A;  4DP3 A;  2H2Q A;  1DRE A;  4DPH A;  3SQY X;  1JUV A;  4HOG A;  3SRW X;  1E26 A;  1RX9 A;  3KY8 A;  2DHF A;  1RB3 A;  3F0B X;  4QI9 A;  2C2T A;  4OSG A;  4TU5 X;  1RB2 A;  3JWC A;  3FQZ A;  3EEM A;  2FZH A;  5ECC A;  4KM0 A;  4HOE A;  1PD9 A;  2HXV A;  3SRU X;  3R33 A;  5HSR A;  4KLX A;  2G6V A;  4NX7 A;  3INV A;  3F8Z A;  4HA7 A;  2HM9 A;  1S3V A;  3QL3 A;  1IA2 A;  2W9S A;  4PDJ A;  2W9T A;  3NXO A;  3NXY A;  1AO8 A;  5U26 A;  1RA9 A;  1RA3 A;  3HJ3 A;  1DYH A;  4PST A;  1HFR A;  2ANO A;  1DLS A;  3NZC X;  3F91 A;  4X5I A;  1DRH A;  2LF1 A;  2BLB A;  3DGA A;  5FDA A;  3OAF A;  4P3Q A;  2D5N A;  3NXT A;  4PSY A;  3F0Q X;  1OHK A;  5ECX A;  3RG9 A;  4QLE A;  1DF7 A;  2W9G A;  3QG2 A;  2W3A A;  1IA4 A;  4ELG A;  3SR5 X;  3S7A A;  1DR4 A;  4PTH A;  4ELB A;  3NXX A;  4G95 A;  5E8Q A;  5HF2 X;  4M6K A;  2W3B A;  1M79 A;  3GHV A;  3CLB A;  3DAT A;  3KGY A;  1SEJ A;  4IXE D;  3E0B A;  3JWF A;  5HVE A;  3NXV A;  3TD8 A;  2FZJ A;  3UM5 A;  1DIU A;  3JSU A;  5DXV A;  3F0S X;  3FYV X;  3NZB X;  1DIS A;  4EIZ A;  2ITH A;  4X5H A;  1RX8 A;  3FL9 A;  3SRR X;  4ELE A;  3EX8 A;  5U27 A;  3K47 A;  3S3V A;  2AZN A;  3SA2 A;  4KFJ A;  1J3J A;  4XRB A;  1DYJ A;  1DHJ A;  3CD2 A;  3F0X X;  3SGY A;  4QJZ D;  3F0V X;  3QYO A;  3FL8 A;  3KJR A;  3NZ6 X;  1U71 A;  1RA8 A;  3FRE X;  2KGK A;  3FQF A;  1MVS A;  2L28 A;  4H95 A;  3VCO A;  1YHO A;  3D80 A;  3FRF X;  3HBB A;  1S3W A;  3FY9 X;  1S3U A;  1JOM A;  4P66 A;  3SA1 A;  3F0U X;  3K45 A;  3FS6 A;  3IRO A;  4Q0D A;  1RC4 A;  3ZPC A;  3FQV A;  3GHW A;  5CCC A;  8DFR A;  2QK8 A;  4FHB A;  3F8Y A;  1RX7 A;  4KY8 A;  3UM8 A;  3SH2 A;  3N0H A;  1MVT A;  2P4G A;  1RA1 A;  3JVX A;  1M78 A;  3KJS A;  1RX6 A;  1DR2 A;  3KFY A;  3NU0 A;  4G8Z X;  1PDB A;  5HQZ A;  3I8A X;  3JWK A;  4GH8 A;  4KJK A;  1LY4 A;  1DHI A;  2W3W A;  1JOL A;  1DG8 A;  4Q0E A;  1DAJ A;  1DDR A;  3DG8 A;  1J3I A;  4XEC X;  1VJ3 A;  2BLA A;  1PD8 A;  4QLG A;  4LAE X;  1KLK A;  1HFQ A;  2FZI A;  2OIP A;  1RX5 A;  3IX9 A;  4DPD A;  4M6L A;  4H98 A;  3QGT A;  2OBC A;  3M09 A;  3NZD A;  2CIG A;  4I13 A;  2CD2 A;  5HUI A;  3QLS A;  3QLW A;  1M7A A;  3QYL A;  3FRD X;  3QFX A;  3I3R A;  1DG7 A;  3TQ8 A;  2BLC A;  1RD7 A;  1RX3 A;  1RF7 A;  4ELH A;  2INQ A;  4FGG A;  2ZZA A;  3JWM A;  4RGC A;  5DFR A;  1LUD A;  4PSS A;  4DDR A;  1DR1 A;  3EEJ A;  3NTZ A;  3QLX A;  3ZPG A;  3K2H A;  5EAJ A;  4KNE A;  3RO9 A;  5JA3 A;  1QZF A;  3K74 A;  4QJC A;  3FQC A;  1U70 A;  1DR3 A;  1RH3 A;  4KJJ A;  4XT5 A;  4EIG A;  5HSU A;  1RX1 A;  3QLY A;  4Q6A A;  5HI6 A;  1RX4 A;  4ELF A;  3QLZ A;  1RG7 A;  4P3R A;  1IA3 A;  5JG0 X;  4H97 A;  3FQO A;  4ECK A;  1U72 A;  3S9U A;  3JW5 A;  4LEK X; 
#chains in the Genus database with same CATH homology
 1BZF A;  6DFR A;  3FYW X;  2ANQ A;  2W9H A;  3D84 X;  3CSE A;  1AOE A;  3GI2 A;  3IA5 A;  4XT7 A;  3LG4 A;  1D1G A;  1DHF A;  2BL9 A;  1AI9 A;  4CD2 A;  1DRA A;  3TQ9 A;  1DG5 A;  4X5F A;  1DYR A;  1HFP A;  4KL9 A;  2W3V A;  1KMV A;  2O7P A;  4FGH A;  1J3K A;  4XT6 A;  1IA1 A;  5HVB A;  5HT4 A;  3IRN A;  3DL5 A;  7DFR A;  3OCH A;  3NZ9 X;  4M7V A;  1DR6 A;  4XT4 A;  3FQ0 A;  2HQP A;  4M6J A;  4EIL A;  4DFR A;  1DR7 A;  4KD7 A;  4XT8 A;  3TQA A;  3IA4 A;  3L3R A;  4Q67 A;  4KJL A;  1KMS A;  1OHJ A;  3JW3 A;  3GHC A;  2XW7 A;  1DRB A;  4EJ1 A;  4G3M A;  1TDR A;  4KEB A;  1S3Y A;  4M7U A;  1DR5 A;  3Q1H A;  3EEK A;  1CZ3 A;  4KAK A;  5HT5 A;  3DFR A;  3NXR A;  1ZDR A;  2JYB A;  1RE7 A;  3M08 A;  4X5J A;  1DRF A;  3JTW A;  4I1N A;  4QHV A;  2D0K A;  4KY4 A;  1DDS A;  3ROA A;  3SAI A;  2GD9 A;  3QLR A;  4HA9 A;  4HOF A;  3GYF A;  3SRQ X;  3EIG A;  4M2X A;  4P68 A;  4X5G A;  4KBN A;  5HQY A;  3QL0 A;  4IXF X;  4H96 A;  3NRR A;  4XE6 X;  4LAG X;  3FRB X;  4LAH X;  4IXG X;  3FY8 X;  3DAU A;  5HF0 X;  4PTJ A;  2C2S A;  4KYA A;  1LY3 A;  4NX6 A;  3FRA X;  4OR7 A;  2DRC A;  3TQB A;  1DLR A;  3DRC A;  1RX2 A;  3IRM A;  1CD2 A;  4QLF A;  2B3Z A;  1RA2 A;  3CL9 A;  3SRS X;  3EEL A;  3UM6 A;  4KM2 A;  1VDR A;  3NZA X;  1BOZ A;  3DL6 A;  5CC9 A;  2W3M A;  5HPB A;  1DYI A;  4DP3 A;  2H2Q A;  1DRE A;  4DPH A;  3SQY X;  1JUV A;  4HOG A;  3SRW X;  1E26 A;  1RX9 A;  3KY8 A;  2DHF A;  1RB3 A;  3F0B X;  4QI9 A;  2C2T A;  4OSG A;  4TU5 X;  1RB2 A;  3JWC A;  3FQZ A;  3EEM A;  2FZH A;  5ECC A;  4KM0 A;  4HOE A;  1PD9 A;  2HXV A;  3SRU X;  3R33 A;  5HSR A;  4KLX A;  2G6V A;  4NX7 A;  3INV A;  3F8Z A;  4HA7 A;  2HM9 A;  1S3V A;  3QL3 A;  1IA2 A;  2W9S A;  4PDJ A;  2W9T A;  3NXO A;  3NXY A;  1AO8 A;  5U26 A;  1RA9 A;  1RA3 A;  3HJ3 A;  1DYH A;  4PST A;  1HFR A;  2ANO A;  1DLS A;  3NZC X;  3F91 A;  4X5I A;  1DRH A;  2LF1 A;  2BLB A;  3DGA A;  5FDA A;  3OAF A;  4P3Q A;  2D5N A;  3NXT A;  4PSY A;  3F0Q X;  1OHK A;  5ECX A;  3RG9 A;  4QLE A;  1DF7 A;  2W9G A;  3QG2 A;  2W3A A;  1IA4 A;  4ELG A;  3SR5 X;  3S7A A;  1DR4 A;  4PTH A;  4ELB A;  3NXX A;  4G95 A;  5E8Q A;  5HF2 X;  4M6K A;  2W3B A;  1M79 A;  3GHV A;  3CLB A;  3DAT A;  3KGY A;  1SEJ A;  4IXE D;  3E0B A;  3JWF A;  5HVE A;  3NXV A;  3TD8 A;  2FZJ A;  3UM5 A;  1DIU A;  3JSU A;  5DXV A;  3F0S X;  3FYV X;  3NZB X;  1DIS A;  4EIZ A;  2ITH A;  4X5H A;  1RX8 A;  3FL9 A;  3SRR X;  4ELE A;  3EX8 A;  5U27 A;  3K47 A;  3S3V A;  2AZN A;  3SA2 A;  4KFJ A;  1J3J A;  4XRB A;  1DYJ A;  1DHJ A;  3CD2 A;  3F0X X;  3SGY A;  4QJZ D;  3F0V X;  3QYO A;  3FL8 A;  3KJR A;  3NZ6 X;  1U71 A;  1RA8 A;  3FRE X;  2KGK A;  3FQF A;  1MVS A;  2L28 A;  4H95 A;  3VCO A;  1YHO A;  3D80 A;  3FRF X;  3HBB A;  1S3W A;  3FY9 X;  1S3U A;  1JOM A;  4P66 A;  3SA1 A;  3F0U X;  3K45 A;  3FS6 A;  3IRO A;  4Q0D A;  1RC4 A;  3ZPC A;  3FQV A;  3GHW A;  5CCC A;  8DFR A;  2QK8 A;  4FHB A;  3F8Y A;  1RX7 A;  4KY8 A;  3UM8 A;  3SH2 A;  3N0H A;  1MVT A;  2P4G A;  1RA1 A;  3JVX A;  1M78 A;  3KJS A;  1RX6 A;  1DR2 A;  3KFY A;  3NU0 A;  4G8Z X;  1PDB A;  5HQZ A;  3I8A X;  3JWK A;  4GH8 A;  4KJK A;  1LY4 A;  1DHI A;  2W3W A;  1JOL A;  1DG8 A;  4Q0E A;  1DAJ A;  1DDR A;  3DG8 A;  1J3I A;  4XEC X;  1VJ3 A;  2BLA A;  1PD8 A;  4QLG A;  4LAE X;  1KLK A;  1HFQ A;  2FZI A;  2OIP A;  1RX5 A;  3IX9 A;  4DPD A;  4M6L A;  4H98 A;  3QGT A;  2OBC A;  3M09 A;  3NZD A;  2CIG A;  4I13 A;  2CD2 A;  5HUI A;  3QLS A;  3QLW A;  1M7A A;  3QYL A;  3FRD X;  3QFX A;  3I3R A;  1DG7 A;  3TQ8 A;  2BLC A;  1RD7 A;  1RX3 A;  1RF7 A;  4ELH A;  2INQ A;  4FGG A;  2ZZA A;  3JWM A;  4RGC A;  5DFR A;  1LUD A;  4PSS A;  4DDR A;  1DR1 A;  3EEJ A;  3NTZ A;  3QLX A;  3ZPG A;  3K2H A;  5EAJ A;  4KNE A;  3RO9 A;  5JA3 A;  1QZF A;  3K74 A;  4QJC A;  3FQC A;  1U70 A;  1DR3 A;  1RH3 A;  4KJJ A;  4XT5 A;  4EIG A;  5HSU A;  1RX1 A;  3QLY A;  4Q6A A;  5HI6 A;  1RX4 A;  4ELF A;  3QLZ A;  1RG7 A;  4P3R A;  1IA3 A;  5JG0 X;  4H97 A;  3FQO A;  4ECK A;  1U72 A;  3S9U A;  3JW5 A;  4LEK X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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