3EEMA

Candida glabrata dihydrofolate reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)prop-1-ynyl]-6-methylpyrimidine(ucp111d26m) and nadph
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
225
structure length
225
Chain Sequence
KVPVVGIVAALLPEMGIGFQGNLPWRLAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQKFRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGEIYRQSMDLADHWLITKIMPLPETTIPQMDTFLQKQELEQRFYDNSDKLVDFLPSSIQLEGRLTSQEWNGELVKGLPVQEKGYQFYFTLYTKKLEHHHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Candida glabrata
publication title Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
total genus 60
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3eemA00
3FYWX 3F0XX 1QZFA 3QYLA 1DRBA 2BLAA 1DG8A 2W9TA 3N0HA 2CIGA 3JVXA 3NXTA 1S3WA 5HUIA 3FYVX 4RGCA 4XT6A 3QLXA 1DIUA 4ELHA 1DF7A 4IXGX 2W3WA 5EAJA 3TQAA 3ZPGA 3DRCA 5E8QA 1DDSA 1DR3A 3FQOA 3QFXA 4X5IA 3SR5X 4H95A 3CL9A 1JOMA 3SA1A 3QLYA 4P3RA 2C2TA 3SGYA 3IRNA 5U26A 4H97A 2JYBA 4PTJA 4IXFX 1M7AA 2GD9A 3UM8A 3UM6A 1KMSA 3F0QX 1RX4A 1RH3A 3F91A 4Q67A 4QLEA 4HOEA 3EEMA 3K2HA 1DRAA 5ECXA 1SEJA 1RB2A 3DL6A 1RX3A 3FRDX 1RB3A 4KJKA 4M2XA 3KGYA 4NX6A 5U27A 1AO8A 2O7PA 2W3VA 2BLBA 4EIZA 1E26A 1KLKA 3NRRA 2D5NA 3QLZA 4XT4A 1PDBA 4ELGA 4KM2A 1IA4A 3SAIA 3JWKA 1RX2A 4XECX 3FQVA 3I8AX 4KFJA 3S9UA 1HFPA 3F0SX 1OHJA 3NXRA 3FS6A 3FQFA 3QLWA 5DFRA 4TU5X 3GHCA 3EIGA 3TQ8A 1DYRA 4HA7A 3F0VX 1J3KA 2C2SA 1U72A 1U70A 4ECKA 1S3UA 5DXVA 3VCOA 4X5FA 1CZ3A 4Q6AA 8DFRA 1VDRA 3NXYA 2D0KA 3SRWX 4KEBA 1S3YA 3FY8X 1RD7A 2QK8A 2W9SA 3EEJA 1RA3A 3NZ9X 2INQA 4QLFA 5HVBA 4PSYA 1RA2A 1RX6A 1PD9A 4PSSA 4QJCA 4KNEA 3OAFA 4X5JA 3EEKA 4M6JA 3NXXA 3FQCA 3SRQX 1MVSA 1J3JA 1MVTA 3GYFA 4ELBA 1DHFA 1RG7A 1JUVA 4HOGA 3NZAX 4I1NA 2FZIA 4X5GA 3IA5A 4EILA 1DLRA 1DYJA 1RX7A 5CC9A 4M6KA 3E0BA 1D1GA 3NXOA 1AI9A 3IRMA 5HF0X 3TD8A 1RC4A 3R33A 3JW3A 3NZBX 4XT8A 1DG7A 4EIGA 3NZCX 1DR5A 3HJ3A 3HBBA 2BL9A 1DLSA 1DYHA 4ELEA 3FQZA 4H98A 3JW5A 1IA3A 2LF1A 1LY3A 4P3QA 3F0BX 5FDAA 4QLGA 4LAHX 3CSEA 3QG2A 4I13A 1U71A 3QL0A 1DYIA 5HQYA 1RE7A 4PSTA 2G6VA 3F8YA 3JWCA 4PDJA 4DPDA 3JWFA 3NZDA 3FREX 4G3MA 4LAGX 2H2QA 2FZHA 2FZJA 3K74A 1LUDA 4CD2A 7DFRA 4P66A 3TQBA 2HM9A 2ITHA 3FRBX 4KAKA 4ELFA 3D80A 1DISA 5HT4A 1YHOA 4QJZD 5HSUA 2OBCA 2CD2A 1DRHA 3RG9A 4KY8A 3DG8A 2W3MA 3FY9X 1RA8A 3NZ6X 1DDRA 2L28A 3FL9A 3IA4A 5CCCA 4KJLA 3EX8A 3QL3A 3INVA 3DFRA 3F0UX 4FHBA 2HXVA 1JOLA 1RX9A 4KY4A 5JA3A 5JG0X 2ZZAA 6DFRA 4LEKX 3CD2A 4FGHA 3S3VA 3SRRX 3EELA 4KD7A 1HFQA 1RA9A 1RF7A 3NU0A 3KFYA 2W9GA 3FRAX 5HI6A 1DR4A 1RA1A 2OIPA 3IX9A 4PTHA 2ANQA 3ZPCA 1CD2A 1DR7A 4KLXA 1DRFA 5ECCA 1M79A 3D84X 1ZDRA 4XRBA 4KJJA 3UM5A 1LY4A 2B3ZA 3OCHA 1RX1A 4G95A 2DRCA 3DAUA 3FQ0A 4XT7A 2ANOA 2BLCA 2XW7A 5HSRA 3SA2A 3K47A 3M08A 3SRUX 1DR1A 3QGTA 1OHKA 4NX7A 1AOEA 2KGKA 4OR7A 4QHVA 2AZNA 4FGGA 3KJSA 2W9HA 1DR2A 1DAJA 4QI9A 3KY8A 4KYAA 3DATA 1TDRA 2P4GA 4LAEX 3RO9A 5HVEA 1VJ3A 1S3VA 3NXVA 4XT5A 4P68A 1IA1A 3I3RA 4X5HA 3F8ZA 1PD8A 3L3RA 1DG5A 3S7AA 2W3BA 3M09A 3QLRA 1DR6A 4HA9A 4IXED 4DP3A 3DGAA 1DHJA 3TQ9A 3DL5A 4GH8A 1RX8A 4G8ZX 4DPHA 3SQYX 3IROA 4H96A 3GHWA 3GHVA 3QLSA 4M7UA 1BZFA 3JSUA 3JWMA 5HQZA 1M78A 4Q0DA 3SRSX 1DREA 3GI2A 3NTZA 3KJRA 4Q0EA 1DHIA 4HOFA 4KM0A 3SH2A 1IA2A 5HT5A 4M7VA 2DHFA 3LG4A 4DDRA 4M6LA 2W3AA 3QYOA 5HPBA 4OSGA 3CLBA 3ROAA 1RX5A 1KMVA 3K45A 1J3IA 2HQPA 4KL9A 1HFRA 4EJ1A 3Q1HA 1BOZA 4XE6X 3FL8A 5HF2X 4KBNA 4DFRA 3JTWA 3FRFX
chains in the Genus database with same CATH superfamily
3FYWX 3F0XX 1QZFA 3QYLA 1DRBA 2BLAA 1DG8A 2W9TA 3N0HA 2CIGA 3JVXA 3NXTA 1S3WA 5HUIA 3FYVX 4RGCA 4XT6A 3QLXA 1DIUA 4ELHA 1DF7A 4IXGX 2W3WA 5EAJA 3TQAA 3ZPGA 3DRCA 5E8QA 1DDSA 1DR3A 3FQOA 3QFXA 4X5IA 3SR5X 4H95A 3CL9A 1JOMA 3SA1A 3QLYA 4P3RA 2C2TA 3SGYA 3IRNA 5U26A 4H97A 2JYBA 4PTJA 4IXFX 1M7AA 2GD9A 3UM8A 3UM6A 1KMSA 3F0QX 1RX4A 1RH3A 3F91A 4Q67A 4QLEA 4HOEA 3EEMA 3K2HA 1DRAA 5ECXA 1SEJA 1RB2A 3DL6A 1RX3A 3FRDX 1RB3A 4KJKA 4M2XA 3KGYA 4NX6A 5U27A 1AO8A 2O7PA 2W3VA 2BLBA 4EIZA 1E26A 1KLKA 3NRRA 2D5NA 3QLZA 4XT4A 1PDBA 4ELGA 4KM2A 1IA4A 3SAIA 3JWKA 1RX2A 4XECX 3FQVA 3I8AX 4KFJA 3S9UA 1HFPA 3F0SX 1OHJA 3NXRA 3FS6A 3FQFA 3QLWA 5DFRA 4TU5X 3GHCA 3EIGA 3TQ8A 1DYRA 4HA7A 3F0VX 1J3KA 2C2SA 1U72A 1U70A 4ECKA 1S3UA 5DXVA 3VCOA 4X5FA 1CZ3A 4Q6AA 8DFRA 1VDRA 3NXYA 2D0KA 3SRWX 4KEBA 1S3YA 3FY8X 1RD7A 2QK8A 2W9SA 3EEJA 1RA3A 3NZ9X 2INQA 4QLFA 5HVBA 4PSYA 1RA2A 1RX6A 1PD9A 4PSSA 4QJCA 4KNEA 3OAFA 4X5JA 3EEKA 4M6JA 3NXXA 3FQCA 3SRQX 1MVSA 1J3JA 1MVTA 3GYFA 4ELBA 1DHFA 1RG7A 1JUVA 4HOGA 3NZAX 4I1NA 2FZIA 4X5GA 3IA5A 4EILA 1DLRA 1DYJA 1RX7A 5CC9A 4M6KA 3E0BA 1D1GA 3NXOA 1AI9A 3IRMA 5HF0X 3TD8A 1RC4A 3R33A 3JW3A 3NZBX 4XT8A 1DG7A 4EIGA 3NZCX 1DR5A 3HJ3A 3HBBA 2BL9A 1DLSA 1DYHA 4ELEA 3FQZA 4H98A 3JW5A 1IA3A 2LF1A 1LY3A 4P3QA 3F0BX 5FDAA 4QLGA 4LAHX 3CSEA 3QG2A 4I13A 1U71A 3QL0A 1DYIA 5HQYA 1RE7A 4PSTA 2G6VA 3F8YA 3JWCA 4PDJA 4DPDA 3JWFA 3NZDA 3FREX 4G3MA 4LAGX 2H2QA 2FZHA 2FZJA 3K74A 1LUDA 4CD2A 7DFRA 4P66A 3TQBA 2HM9A 2ITHA 3FRBX 4KAKA 4ELFA 3D80A 1DISA 5HT4A 1YHOA 4QJZD 5HSUA 2OBCA 2CD2A 1DRHA 3RG9A 4KY8A 3DG8A 2W3MA 3FY9X 1RA8A 3NZ6X 1DDRA 2L28A 3FL9A 3IA4A 5CCCA 4KJLA 3EX8A 3QL3A 3INVA 3DFRA 3F0UX 4FHBA 2HXVA 1JOLA 1RX9A 4KY4A 5JA3A 5JG0X 2ZZAA 6DFRA 4LEKX 3CD2A 4FGHA 3S3VA 3SRRX 3EELA 4KD7A 1HFQA 1RA9A 1RF7A 3NU0A 3KFYA 2W9GA 3FRAX 5HI6A 1DR4A 1RA1A 2OIPA 3IX9A 4PTHA 2ANQA 3ZPCA 1CD2A 1DR7A 4KLXA 1DRFA 5ECCA 1M79A 3D84X 1ZDRA 4XRBA 4KJJA 3UM5A 1LY4A 2B3ZA 3OCHA 1RX1A 4G95A 2DRCA 3DAUA 3FQ0A 4XT7A 2ANOA 2BLCA 2XW7A 5HSRA 3SA2A 3K47A 3M08A 3SRUX 1DR1A 3QGTA 1OHKA 4NX7A 1AOEA 2KGKA 4OR7A 4QHVA 2AZNA 4FGGA 3KJSA 2W9HA 1DR2A 1DAJA 4QI9A 3KY8A 4KYAA 3DATA 1TDRA 2P4GA 4LAEX 3RO9A 5HVEA 1VJ3A 1S3VA 3NXVA 4XT5A 4P68A 1IA1A 3I3RA 4X5HA 3F8ZA 1PD8A 3L3RA 1DG5A 3S7AA 2W3BA 3M09A 3QLRA 1DR6A 4HA9A 4IXED 4DP3A 3DGAA 1DHJA 3TQ9A 3DL5A 4GH8A 1RX8A 4G8ZX 4DPHA 3SQYX 3IROA 4H96A 3GHWA 3GHVA 3QLSA 4M7UA 1BZFA 3JSUA 3JWMA 5HQZA 1M78A 4Q0DA 3SRSX 1DREA 3GI2A 3NTZA 3KJRA 4Q0EA 1DHIA 4HOFA 4KM0A 3SH2A 1IA2A 5HT5A 4M7VA 2DHFA 3LG4A 4DDRA 4M6LA 2W3AA 3QYOA 5HPBA 4OSGA 3CLBA 3ROAA 1RX5A 1KMVA 3K45A 1J3IA 2HQPA 4KL9A 1HFRA 4EJ1A 3Q1HA 1BOZA 4XE6X 3FL8A 5HF2X 4KBNA 4DFRA 3JTWA 3FRFX
chains in the Genus database with same CATH topology
3FYWX 3F0XX 1QZFA 3QYLA 1DRBA 2BLAA 1DG8A 2W9TA 3N0HA 2CIGA 3JVXA 3NXTA 1S3WA 5HUIA 3FYVX 4RGCA 4XT6A 3QLXA 1DIUA 4ELHA 1DF7A 4IXGX 2W3WA 5EAJA 3TQAA 3ZPGA 3DRCA 5E8QA 1DDSA 1DR3A 3FQOA 3QFXA 4X5IA 3SR5X 4H95A 3CL9A 1JOMA 3SA1A 3QLYA 4P3RA 2C2TA 3SGYA 3IRNA 5U26A 4H97A 2JYBA 4PTJA 4IXFX 1M7AA 2GD9A 3UM8A 3UM6A 1KMSA 3F0QX 1RX4A 1RH3A 3F91A 4Q67A 4QLEA 4HOEA 3EEMA 3K2HA 1DRAA 5ECXA 1SEJA 1RB2A 3DL6A 1RX3A 3FRDX 1RB3A 4KJKA 4M2XA 3KGYA 4NX6A 5U27A 1AO8A 2O7PA 2W3VA 2BLBA 4EIZA 1E26A 1KLKA 3NRRA 2D5NA 3QLZA 4XT4A 1PDBA 4ELGA 4KM2A 1IA4A 3SAIA 3JWKA 1RX2A 4XECX 3FQVA 3I8AX 4KFJA 3S9UA 1HFPA 3F0SX 1OHJA 3NXRA 3FS6A 3FQFA 3QLWA 5DFRA 4TU5X 3GHCA 3EIGA 3TQ8A 1DYRA 4HA7A 3F0VX 1J3KA 2C2SA 1U72A 1U70A 4ECKA 1S3UA 5DXVA 3VCOA 4X5FA 1CZ3A 4Q6AA 8DFRA 1VDRA 3NXYA 2D0KA 3SRWX 4KEBA 1S3YA 3FY8X 1RD7A 2QK8A 2W9SA 3EEJA 1RA3A 3NZ9X 2INQA 4QLFA 5HVBA 4PSYA 1RA2A 1RX6A 1PD9A 4PSSA 4QJCA 4KNEA 3OAFA 4X5JA 3EEKA 4M6JA 3NXXA 3FQCA 3SRQX 1MVSA 1J3JA 1MVTA 3GYFA 4ELBA 1DHFA 1RG7A 1JUVA 4HOGA 3NZAX 4I1NA 2FZIA 4X5GA 3IA5A 4EILA 1DLRA 1DYJA 1RX7A 5CC9A 4M6KA 3E0BA 1D1GA 3NXOA 1AI9A 3IRMA 5HF0X 3TD8A 1RC4A 3R33A 3JW3A 3NZBX 4XT8A 1DG7A 4EIGA 3NZCX 1DR5A 3HJ3A 3HBBA 2BL9A 1DLSA 1DYHA 4ELEA 3FQZA 4H98A 3JW5A 1IA3A 2LF1A 1LY3A 4P3QA 3F0BX 5FDAA 4QLGA 4LAHX 3CSEA 3QG2A 4I13A 1U71A 3QL0A 1DYIA 5HQYA 1RE7A 4PSTA 2G6VA 3F8YA 3JWCA 4PDJA 4DPDA 3JWFA 3NZDA 3FREX 4G3MA 4LAGX 2H2QA 2FZHA 2FZJA 3K74A 1LUDA 4CD2A 7DFRA 4P66A 3TQBA 2HM9A 2ITHA 3FRBX 4KAKA 4ELFA 3D80A 1DISA 5HT4A 1YHOA 4QJZD 5HSUA 2OBCA 2CD2A 1DRHA 3RG9A 4KY8A 3DG8A 2W3MA 3FY9X 1RA8A 3NZ6X 1DDRA 2L28A 3FL9A 3IA4A 5CCCA 4KJLA 3EX8A 3QL3A 3INVA 3DFRA 3F0UX 4FHBA 2HXVA 1JOLA 1RX9A 4KY4A 5JA3A 5JG0X 2ZZAA 6DFRA 4LEKX 3CD2A 4FGHA 3S3VA 3SRRX 3EELA 4KD7A 1HFQA 1RA9A 1RF7A 3NU0A 3KFYA 2W9GA 3FRAX 5HI6A 1DR4A 1RA1A 2OIPA 3IX9A 4PTHA 2ANQA 3ZPCA 1CD2A 1DR7A 4KLXA 1DRFA 5ECCA 1M79A 3D84X 1ZDRA 4XRBA 4KJJA 3UM5A 1LY4A 2B3ZA 3OCHA 1RX1A 4G95A 2DRCA 3DAUA 3FQ0A 4XT7A 2ANOA 2BLCA 2XW7A 5HSRA 3SA2A 3K47A 3M08A 3SRUX 1DR1A 3QGTA 1OHKA 4NX7A 1AOEA 2KGKA 4OR7A 4QHVA 2AZNA 4FGGA 3KJSA 2W9HA 1DR2A 1DAJA 4QI9A 3KY8A 4KYAA 3DATA 1TDRA 2P4GA 4LAEX 3RO9A 5HVEA 1VJ3A 1S3VA 3NXVA 4XT5A 4P68A 1IA1A 3I3RA 4X5HA 3F8ZA 1PD8A 3L3RA 1DG5A 3S7AA 2W3BA 3M09A 3QLRA 1DR6A 4HA9A 4IXED 4DP3A 3DGAA 1DHJA 3TQ9A 3DL5A 4GH8A 1RX8A 4G8ZX 4DPHA 3SQYX 3IROA 4H96A 3GHWA 3GHVA 3QLSA 4M7UA 1BZFA 3JSUA 3JWMA 5HQZA 1M78A 4Q0DA 3SRSX 1DREA 3GI2A 3NTZA 3KJRA 4Q0EA 1DHIA 4HOFA 4KM0A 3SH2A 1IA2A 5HT5A 4M7VA 2DHFA 3LG4A 4DDRA 4M6LA 2W3AA 3QYOA 5HPBA 4OSGA 3CLBA 3ROAA 1RX5A 1KMVA 3K45A 1J3IA 2HQPA 4KL9A 1HFRA 4EJ1A 3Q1HA 1BOZA 4XE6X 3FL8A 5HF2X 4KBNA 4DFRA 3JTWA 3FRFX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FYW X;  3F0X X;  1QZF A;  3QYL A;  1DRB A;  2BLA A;  1DG8 A;  2W9T A;  3N0H A;  2CIG A;  3JVX A;  3NXT A;  1S3W A;  5HUI A;  3FYV X;  4RGC A;  4XT6 A;  3QLX A;  1DIU A;  4ELH A;  1DF7 A;  4IXG X;  2W3W A;  5EAJ A;  3TQA A;  3ZPG A;  3DRC A;  5E8Q A;  1DDS A;  1DR3 A;  3FQO A;  3QFX A;  4X5I A;  3SR5 X;  4H95 A;  3CL9 A;  1JOM A;  3SA1 A;  3QLY A;  4P3R A;  2C2T A;  3SGY A;  3IRN A;  5U26 A;  4H97 A;  2JYB A;  4PTJ A;  4IXF X;  1M7A A;  2GD9 A;  3UM8 A;  3UM6 A;  1KMS A;  3F0Q X;  1RX4 A;  1RH3 A;  3F91 A;  4Q67 A;  4QLE A;  4HOE A;  3EEM A;  3K2H A;  1DRA A;  5ECX A;  1SEJ A;  1RB2 A;  3DL6 A;  1RX3 A;  3FRD X;  1RB3 A;  4KJK A;  4M2X A;  3KGY A;  4NX6 A;  5U27 A;  1AO8 A;  2O7P A;  2W3V A;  2BLB A;  4EIZ A;  1E26 A;  1KLK A;  3NRR A;  2D5N A;  3QLZ A;  4XT4 A;  1PDB A;  4ELG A;  4KM2 A;  1IA4 A;  3SAI A;  3JWK A;  1RX2 A;  4XEC X;  3FQV A;  3I8A X;  4KFJ A;  3S9U A;  1HFP A;  3F0S X;  1OHJ A;  3NXR A;  3FS6 A;  3FQF A;  3QLW A;  5DFR A;  4TU5 X;  3GHC A;  3EIG A;  3TQ8 A;  1DYR A;  4HA7 A;  3F0V X;  1J3K A;  2C2S A;  1U72 A;  1U70 A;  4ECK A;  1S3U A;  5DXV A;  3VCO A;  4X5F A;  1CZ3 A;  4Q6A A;  8DFR A;  1VDR A;  3NXY A;  2D0K A;  3SRW X;  4KEB A;  1S3Y A;  3FY8 X;  1RD7 A;  2QK8 A;  2W9S A;  3EEJ A;  1RA3 A;  3NZ9 X;  2INQ A;  4QLF A;  5HVB A;  4PSY A;  1RA2 A;  1RX6 A;  1PD9 A;  4PSS A;  4QJC A;  4KNE A;  3OAF A;  4X5J A;  3EEK A;  4M6J A;  3NXX A;  3FQC A;  3SRQ X;  1MVS A;  1J3J A;  1MVT A;  3GYF A;  4ELB A;  1DHF A;  1RG7 A;  1JUV A;  4HOG A;  3NZA X;  4I1N A;  2FZI A;  4X5G A;  3IA5 A;  4EIL A;  1DLR A;  1DYJ A;  1RX7 A;  5CC9 A;  4M6K A;  3E0B A;  1D1G A;  3NXO A;  1AI9 A;  3IRM A;  5HF0 X;  3TD8 A;  1RC4 A;  3R33 A;  3JW3 A;  3NZB X;  4XT8 A;  1DG7 A;  4EIG A;  3NZC X;  1DR5 A;  3HJ3 A;  3HBB A;  2BL9 A;  1DLS A;  1DYH A;  4ELE A;  3FQZ A;  4H98 A;  3JW5 A;  1IA3 A;  2LF1 A;  1LY3 A;  4P3Q A;  3F0B X;  5FDA A;  4QLG A;  4LAH X;  3CSE A;  3QG2 A;  4I13 A;  1U71 A;  3QL0 A;  1DYI A;  5HQY A;  1RE7 A;  4PST A;  2G6V A;  3F8Y A;  3JWC A;  4PDJ A;  4DPD A;  3JWF A;  3NZD A;  3FRE X;  4G3M A;  4LAG X;  2H2Q A;  2FZH A;  2FZJ A;  3K74 A;  1LUD A;  4CD2 A;  7DFR A;  4P66 A;  3TQB A;  2HM9 A;  2ITH A;  3FRB X;  4KAK A;  4ELF A;  3D80 A;  1DIS A;  5HT4 A;  1YHO A;  4QJZ D;  5HSU A;  2OBC A;  2CD2 A;  1DRH A;  3RG9 A;  4KY8 A;  3DG8 A;  2W3M A;  3FY9 X;  1RA8 A;  3NZ6 X;  1DDR A;  2L28 A;  3FL9 A;  3IA4 A;  5CCC A;  4KJL A;  3EX8 A;  3QL3 A;  3INV A;  3DFR A;  3F0U X;  4FHB A;  2HXV A;  1JOL A;  1RX9 A;  4KY4 A;  5JA3 A;  5JG0 X;  2ZZA A;  6DFR A;  4LEK X;  3CD2 A;  4FGH A;  3S3V A;  3SRR X;  3EEL A;  4KD7 A;  1HFQ A;  1RA9 A;  1RF7 A;  3NU0 A;  3KFY A;  2W9G A;  3FRA X;  5HI6 A;  1DR4 A;  1RA1 A;  2OIP A;  3IX9 A;  4PTH A;  2ANQ A;  3ZPC A;  1CD2 A;  1DR7 A;  4KLX A;  1DRF A;  5ECC A;  1M79 A;  3D84 X;  1ZDR A;  4XRB A;  4KJJ A;  3UM5 A;  1LY4 A;  2B3Z A;  3OCH A;  1RX1 A;  4G95 A;  2DRC A;  3DAU A;  3FQ0 A;  4XT7 A;  2ANO A;  2BLC A;  2XW7 A;  5HSR A;  3SA2 A;  3K47 A;  3M08 A;  3SRU X;  1DR1 A;  3QGT A;  1OHK A;  4NX7 A;  1AOE A;  2KGK A;  4OR7 A;  4QHV A;  2AZN A;  4FGG A;  3KJS A;  2W9H A;  1DR2 A;  1DAJ A;  4QI9 A;  3KY8 A;  4KYA A;  3DAT A;  1TDR A;  2P4G A;  4LAE X;  3RO9 A;  5HVE A;  1VJ3 A;  1S3V A;  3NXV A;  4XT5 A;  4P68 A;  1IA1 A;  3I3R A;  4X5H A;  3F8Z A;  1PD8 A;  3L3R A;  1DG5 A;  3S7A A;  2W3B A;  3M09 A;  3QLR A;  1DR6 A;  4HA9 A;  4IXE D;  4DP3 A;  3DGA A;  1DHJ A;  3TQ9 A;  3DL5 A;  4GH8 A;  1RX8 A;  4G8Z X;  4DPH A;  3SQY X;  3IRO A;  4H96 A;  3GHW A;  3GHV A;  3QLS A;  4M7U A;  1BZF A;  3JSU A;  3JWM A;  5HQZ A;  1M78 A;  4Q0D A;  3SRS X;  1DRE A;  3GI2 A;  3NTZ A;  3KJR A;  4Q0E A;  1DHI A;  4HOF A;  4KM0 A;  3SH2 A;  1IA2 A;  5HT5 A;  4M7V A;  2DHF A;  3LG4 A;  4DDR A;  4M6L A;  2W3A A;  3QYO A;  5HPB A;  4OSG A;  3CLB A;  3ROA A;  1RX5 A;  1KMV A;  3K45 A;  1J3I A;  2HQP A;  4KL9 A;  1HFR A;  4EJ1 A;  3Q1H A;  1BOZ A;  4XE6 X;  3FL8 A;  5HF2 X;  4KBN A;  4DFR A;  3JTW A;  3FRF X; 
#chains in the Genus database with same CATH topology
 3FYW X;  3F0X X;  1QZF A;  3QYL A;  1DRB A;  2BLA A;  1DG8 A;  2W9T A;  3N0H A;  2CIG A;  3JVX A;  3NXT A;  1S3W A;  5HUI A;  3FYV X;  4RGC A;  4XT6 A;  3QLX A;  1DIU A;  4ELH A;  1DF7 A;  4IXG X;  2W3W A;  5EAJ A;  3TQA A;  3ZPG A;  3DRC A;  5E8Q A;  1DDS A;  1DR3 A;  3FQO A;  3QFX A;  4X5I A;  3SR5 X;  4H95 A;  3CL9 A;  1JOM A;  3SA1 A;  3QLY A;  4P3R A;  2C2T A;  3SGY A;  3IRN A;  5U26 A;  4H97 A;  2JYB A;  4PTJ A;  4IXF X;  1M7A A;  2GD9 A;  3UM8 A;  3UM6 A;  1KMS A;  3F0Q X;  1RX4 A;  1RH3 A;  3F91 A;  4Q67 A;  4QLE A;  4HOE A;  3EEM A;  3K2H A;  1DRA A;  5ECX A;  1SEJ A;  1RB2 A;  3DL6 A;  1RX3 A;  3FRD X;  1RB3 A;  4KJK A;  4M2X A;  3KGY A;  4NX6 A;  5U27 A;  1AO8 A;  2O7P A;  2W3V A;  2BLB A;  4EIZ A;  1E26 A;  1KLK A;  3NRR A;  2D5N A;  3QLZ A;  4XT4 A;  1PDB A;  4ELG A;  4KM2 A;  1IA4 A;  3SAI A;  3JWK A;  1RX2 A;  4XEC X;  3FQV A;  3I8A X;  4KFJ A;  3S9U A;  1HFP A;  3F0S X;  1OHJ A;  3NXR A;  3FS6 A;  3FQF A;  3QLW A;  5DFR A;  4TU5 X;  3GHC A;  3EIG A;  3TQ8 A;  1DYR A;  4HA7 A;  3F0V X;  1J3K A;  2C2S A;  1U72 A;  1U70 A;  4ECK A;  1S3U A;  5DXV A;  3VCO A;  4X5F A;  1CZ3 A;  4Q6A A;  8DFR A;  1VDR A;  3NXY A;  2D0K A;  3SRW X;  4KEB A;  1S3Y A;  3FY8 X;  1RD7 A;  2QK8 A;  2W9S A;  3EEJ A;  1RA3 A;  3NZ9 X;  2INQ A;  4QLF A;  5HVB A;  4PSY A;  1RA2 A;  1RX6 A;  1PD9 A;  4PSS A;  4QJC A;  4KNE A;  3OAF A;  4X5J A;  3EEK A;  4M6J A;  3NXX A;  3FQC A;  3SRQ X;  1MVS A;  1J3J A;  1MVT A;  3GYF A;  4ELB A;  1DHF A;  1RG7 A;  1JUV A;  4HOG A;  3NZA X;  4I1N A;  2FZI A;  4X5G A;  3IA5 A;  4EIL A;  1DLR A;  1DYJ A;  1RX7 A;  5CC9 A;  4M6K A;  3E0B A;  1D1G A;  3NXO A;  1AI9 A;  3IRM A;  5HF0 X;  3TD8 A;  1RC4 A;  3R33 A;  3JW3 A;  3NZB X;  4XT8 A;  1DG7 A;  4EIG A;  3NZC X;  1DR5 A;  3HJ3 A;  3HBB A;  2BL9 A;  1DLS A;  1DYH A;  4ELE A;  3FQZ A;  4H98 A;  3JW5 A;  1IA3 A;  2LF1 A;  1LY3 A;  4P3Q A;  3F0B X;  5FDA A;  4QLG A;  4LAH X;  3CSE A;  3QG2 A;  4I13 A;  1U71 A;  3QL0 A;  1DYI A;  5HQY A;  1RE7 A;  4PST A;  2G6V A;  3F8Y A;  3JWC A;  4PDJ A;  4DPD A;  3JWF A;  3NZD A;  3FRE X;  4G3M A;  4LAG X;  2H2Q A;  2FZH A;  2FZJ A;  3K74 A;  1LUD A;  4CD2 A;  7DFR A;  4P66 A;  3TQB A;  2HM9 A;  2ITH A;  3FRB X;  4KAK A;  4ELF A;  3D80 A;  1DIS A;  5HT4 A;  1YHO A;  4QJZ D;  5HSU A;  2OBC A;  2CD2 A;  1DRH A;  3RG9 A;  4KY8 A;  3DG8 A;  2W3M A;  3FY9 X;  1RA8 A;  3NZ6 X;  1DDR A;  2L28 A;  3FL9 A;  3IA4 A;  5CCC A;  4KJL A;  3EX8 A;  3QL3 A;  3INV A;  3DFR A;  3F0U X;  4FHB A;  2HXV A;  1JOL A;  1RX9 A;  4KY4 A;  5JA3 A;  5JG0 X;  2ZZA A;  6DFR A;  4LEK X;  3CD2 A;  4FGH A;  3S3V A;  3SRR X;  3EEL A;  4KD7 A;  1HFQ A;  1RA9 A;  1RF7 A;  3NU0 A;  3KFY A;  2W9G A;  3FRA X;  5HI6 A;  1DR4 A;  1RA1 A;  2OIP A;  3IX9 A;  4PTH A;  2ANQ A;  3ZPC A;  1CD2 A;  1DR7 A;  4KLX A;  1DRF A;  5ECC A;  1M79 A;  3D84 X;  1ZDR A;  4XRB A;  4KJJ A;  3UM5 A;  1LY4 A;  2B3Z A;  3OCH A;  1RX1 A;  4G95 A;  2DRC A;  3DAU A;  3FQ0 A;  4XT7 A;  2ANO A;  2BLC A;  2XW7 A;  5HSR A;  3SA2 A;  3K47 A;  3M08 A;  3SRU X;  1DR1 A;  3QGT A;  1OHK A;  4NX7 A;  1AOE A;  2KGK A;  4OR7 A;  4QHV A;  2AZN A;  4FGG A;  3KJS A;  2W9H A;  1DR2 A;  1DAJ A;  4QI9 A;  3KY8 A;  4KYA A;  3DAT A;  1TDR A;  2P4G A;  4LAE X;  3RO9 A;  5HVE A;  1VJ3 A;  1S3V A;  3NXV A;  4XT5 A;  4P68 A;  1IA1 A;  3I3R A;  4X5H A;  3F8Z A;  1PD8 A;  3L3R A;  1DG5 A;  3S7A A;  2W3B A;  3M09 A;  3QLR A;  1DR6 A;  4HA9 A;  4IXE D;  4DP3 A;  3DGA A;  1DHJ A;  3TQ9 A;  3DL5 A;  4GH8 A;  1RX8 A;  4G8Z X;  4DPH A;  3SQY X;  3IRO A;  4H96 A;  3GHW A;  3GHV A;  3QLS A;  4M7U A;  1BZF A;  3JSU A;  3JWM A;  5HQZ A;  1M78 A;  4Q0D A;  3SRS X;  1DRE A;  3GI2 A;  3NTZ A;  3KJR A;  4Q0E A;  1DHI A;  4HOF A;  4KM0 A;  3SH2 A;  1IA2 A;  5HT5 A;  4M7V A;  2DHF A;  3LG4 A;  4DDR A;  4M6L A;  2W3A A;  3QYO A;  5HPB A;  4OSG A;  3CLB A;  3ROA A;  1RX5 A;  1KMV A;  3K45 A;  1J3I A;  2HQP A;  4KL9 A;  1HFR A;  4EJ1 A;  3Q1H A;  1BOZ A;  4XE6 X;  3FL8 A;  5HF2 X;  4KBN A;  4DFR A;  3JTW A;  3FRF X; 
#chains in the Genus database with same CATH homology
 3FYW X;  3F0X X;  1QZF A;  3QYL A;  1DRB A;  2BLA A;  1DG8 A;  2W9T A;  3N0H A;  2CIG A;  3JVX A;  3NXT A;  1S3W A;  5HUI A;  3FYV X;  4RGC A;  4XT6 A;  3QLX A;  1DIU A;  4ELH A;  1DF7 A;  4IXG X;  2W3W A;  5EAJ A;  3TQA A;  3ZPG A;  3DRC A;  5E8Q A;  1DDS A;  1DR3 A;  3FQO A;  3QFX A;  4X5I A;  3SR5 X;  4H95 A;  3CL9 A;  1JOM A;  3SA1 A;  3QLY A;  4P3R A;  2C2T A;  3SGY A;  3IRN A;  5U26 A;  4H97 A;  2JYB A;  4PTJ A;  4IXF X;  1M7A A;  2GD9 A;  3UM8 A;  3UM6 A;  1KMS A;  3F0Q X;  1RX4 A;  1RH3 A;  3F91 A;  4Q67 A;  4QLE A;  4HOE A;  3EEM A;  3K2H A;  1DRA A;  5ECX A;  1SEJ A;  1RB2 A;  3DL6 A;  1RX3 A;  3FRD X;  1RB3 A;  4KJK A;  4M2X A;  3KGY A;  4NX6 A;  5U27 A;  1AO8 A;  2O7P A;  2W3V A;  2BLB A;  4EIZ A;  1E26 A;  1KLK A;  3NRR A;  2D5N A;  3QLZ A;  4XT4 A;  1PDB A;  4ELG A;  4KM2 A;  1IA4 A;  3SAI A;  3JWK A;  1RX2 A;  4XEC X;  3FQV A;  3I8A X;  4KFJ A;  3S9U A;  1HFP A;  3F0S X;  1OHJ A;  3NXR A;  3FS6 A;  3FQF A;  3QLW A;  5DFR A;  4TU5 X;  3GHC A;  3EIG A;  3TQ8 A;  1DYR A;  4HA7 A;  3F0V X;  1J3K A;  2C2S A;  1U72 A;  1U70 A;  4ECK A;  1S3U A;  5DXV A;  3VCO A;  4X5F A;  1CZ3 A;  4Q6A A;  8DFR A;  1VDR A;  3NXY A;  2D0K A;  3SRW X;  4KEB A;  1S3Y A;  3FY8 X;  1RD7 A;  2QK8 A;  2W9S A;  3EEJ A;  1RA3 A;  3NZ9 X;  2INQ A;  4QLF A;  5HVB A;  4PSY A;  1RA2 A;  1RX6 A;  1PD9 A;  4PSS A;  4QJC A;  4KNE A;  3OAF A;  4X5J A;  3EEK A;  4M6J A;  3NXX A;  3FQC A;  3SRQ X;  1MVS A;  1J3J A;  1MVT A;  3GYF A;  4ELB A;  1DHF A;  1RG7 A;  1JUV A;  4HOG A;  3NZA X;  4I1N A;  2FZI A;  4X5G A;  3IA5 A;  4EIL A;  1DLR A;  1DYJ A;  1RX7 A;  5CC9 A;  4M6K A;  3E0B A;  1D1G A;  3NXO A;  1AI9 A;  3IRM A;  5HF0 X;  3TD8 A;  1RC4 A;  3R33 A;  3JW3 A;  3NZB X;  4XT8 A;  1DG7 A;  4EIG A;  3NZC X;  1DR5 A;  3HJ3 A;  3HBB A;  2BL9 A;  1DLS A;  1DYH A;  4ELE A;  3FQZ A;  4H98 A;  3JW5 A;  1IA3 A;  2LF1 A;  1LY3 A;  4P3Q A;  3F0B X;  5FDA A;  4QLG A;  4LAH X;  3CSE A;  3QG2 A;  4I13 A;  1U71 A;  3QL0 A;  1DYI A;  5HQY A;  1RE7 A;  4PST A;  2G6V A;  3F8Y A;  3JWC A;  4PDJ A;  4DPD A;  3JWF A;  3NZD A;  3FRE X;  4G3M A;  4LAG X;  2H2Q A;  2FZH A;  2FZJ A;  3K74 A;  1LUD A;  4CD2 A;  7DFR A;  4P66 A;  3TQB A;  2HM9 A;  2ITH A;  3FRB X;  4KAK A;  4ELF A;  3D80 A;  1DIS A;  5HT4 A;  1YHO A;  4QJZ D;  5HSU A;  2OBC A;  2CD2 A;  1DRH A;  3RG9 A;  4KY8 A;  3DG8 A;  2W3M A;  3FY9 X;  1RA8 A;  3NZ6 X;  1DDR A;  2L28 A;  3FL9 A;  3IA4 A;  5CCC A;  4KJL A;  3EX8 A;  3QL3 A;  3INV A;  3DFR A;  3F0U X;  4FHB A;  2HXV A;  1JOL A;  1RX9 A;  4KY4 A;  5JA3 A;  5JG0 X;  2ZZA A;  6DFR A;  4LEK X;  3CD2 A;  4FGH A;  3S3V A;  3SRR X;  3EEL A;  4KD7 A;  1HFQ A;  1RA9 A;  1RF7 A;  3NU0 A;  3KFY A;  2W9G A;  3FRA X;  5HI6 A;  1DR4 A;  1RA1 A;  2OIP A;  3IX9 A;  4PTH A;  2ANQ A;  3ZPC A;  1CD2 A;  1DR7 A;  4KLX A;  1DRF A;  5ECC A;  1M79 A;  3D84 X;  1ZDR A;  4XRB A;  4KJJ A;  3UM5 A;  1LY4 A;  2B3Z A;  3OCH A;  1RX1 A;  4G95 A;  2DRC A;  3DAU A;  3FQ0 A;  4XT7 A;  2ANO A;  2BLC A;  2XW7 A;  5HSR A;  3SA2 A;  3K47 A;  3M08 A;  3SRU X;  1DR1 A;  3QGT A;  1OHK A;  4NX7 A;  1AOE A;  2KGK A;  4OR7 A;  4QHV A;  2AZN A;  4FGG A;  3KJS A;  2W9H A;  1DR2 A;  1DAJ A;  4QI9 A;  3KY8 A;  4KYA A;  3DAT A;  1TDR A;  2P4G A;  4LAE X;  3RO9 A;  5HVE A;  1VJ3 A;  1S3V A;  3NXV A;  4XT5 A;  4P68 A;  1IA1 A;  3I3R A;  4X5H A;  3F8Z A;  1PD8 A;  3L3R A;  1DG5 A;  3S7A A;  2W3B A;  3M09 A;  3QLR A;  1DR6 A;  4HA9 A;  4IXE D;  4DP3 A;  3DGA A;  1DHJ A;  3TQ9 A;  3DL5 A;  4GH8 A;  1RX8 A;  4G8Z X;  4DPH A;  3SQY X;  3IRO A;  4H96 A;  3GHW A;  3GHV A;  3QLS A;  4M7U A;  1BZF A;  3JSU A;  3JWM A;  5HQZ A;  1M78 A;  4Q0D A;  3SRS X;  1DRE A;  3GI2 A;  3NTZ A;  3KJR A;  4Q0E A;  1DHI A;  4HOF A;  4KM0 A;  3SH2 A;  1IA2 A;  5HT5 A;  4M7V A;  2DHF A;  3LG4 A;  4DDR A;  4M6L A;  2W3A A;  3QYO A;  5HPB A;  4OSG A;  3CLB A;  3ROA A;  1RX5 A;  1KMV A;  3K45 A;  1J3I A;  2HQP A;  4KL9 A;  1HFR A;  4EJ1 A;  3Q1H A;  1BOZ A;  4XE6 X;  3FL8 A;  5HF2 X;  4KBN A;  4DFR A;  3JTW A;  3FRF X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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