3FL8A

Crystal structure of b. anthracis dihydrofolate reductase (dhfr) with rab1, a tmp-dihydrophthalazine derivative
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
166
structure length
166
Chain Sequence
MIVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQLVPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Bacillus anthracis
publication title Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
total genus 41
structure length 166
sequence length 166
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fl8A00
3JWMA 1KMSA 3GYFA 3FL9A 2HXVA 3IX9A 4Q0DA 2BLCA 4XT4A 4LAGX 3CD2A 3FQZA 5HSUA 3QLXA 3ROAA 1HFQA 3SRSX 2HQPA 3CLBA 1IA2A 3F0SX 3INVA 2INQA 4EJ1A 1U72A 3SR5X 2G6VA 1HFPA 1RA1A 4G95A 1JOMA 2P4GA 3QLZA 2C2TA 4XT7A 3DGAA 1LUDA 4KYAA 2JYBA 2W9GA 1RA2A 4G8ZX 1S3YA 2W9SA 4PTHA 3K47A 5HF0X 1PDBA 3ZPGA 4KJJA 4DPHA 4P68A 4PTJA 1DYRA 3TQBA 4KY4A 3LG4A 1DR3A 1DR5A 3VCOA 1RD7A 3FYVX 1RX4A 2ZZAA 5CC9A 1IA1A 4M2XA 1J3JA 1DRFA 1DRAA 4LAHX 5HF2X 3S3VA 4ELEA 4DDRA 1KLKA 5HQYA 1RX3A 1PD8A 3DRCA 2W9HA 4KY8A 3NRRA 3NXXA 3DAUA 5HPBA 4KLXA 3F0XX 3TD8A 3ZPCA 5DFRA 2DRCA 3CL9A 1RA3A 1BZFA 3JVXA 3NZ6X 3OAFA 3EIGA 3K2HA 5HVBA 3TQ9A 5ECXA 1DR7A 3F0UX 3GHCA 4EIGA 3FQOA 4QLGA 5HT5A 4H95A 1RA8A 3DL6A 1DG8A 1HFRA 4GH8A 1DISA 4KBNA 3M08A 3QLRA 1DAJA 2CIGA 2W3MA 2BLAA 3JWCA 4FGGA 1DRBA 4CD2A 1S3VA 1M78A 1M7AA 4XRBA 3RG9A 1S3WA 3HBBA 3SA1A 3K74A 2OIPA 3UM5A 3SRRX 3IRNA 3EX8A 3F0QX 5HT4A 3KJSA 2C2SA 1D1GA 1E26A 3NXOA 4H97A 8DFRA 1RX2A 3S9UA 4ELFA 3N0HA 4M6JA 4X5FA 4PSTA 4X5GA 2W3WA 3I3RA 1ZDRA 5JA3A 4I1NA 3M09A 3DG8A 3F0VX 1DR2A 2BLBA 1DF7A 3NTZA 3F0BX 3SA2A 3NU0A 1DRHA 3QYOA 1JUVA 4Q0EA 3IA5A 1DREA 3CSEA 4KNEA 3JW5A 1BOZA 1RE7A 2H2QA 2D0KA 3NXTA 3F8ZA 3QLSA 4M6LA 1DIUA 2W3AA 3D80A 5JG0X 3SAIA 4XT8A 4I13A 3HJ3A 1DR1A 1RX8A 1J3KA 3SRQX 6DFRA 4HOEA 1RB3A 2ANOA 3NZAX 3NXRA 3QL3A 3KFYA 4M6KA 3F91A 4KM0A 4QJCA 3JWKA 2AZNA 3FRFX 2CD2A 3L3RA 4X5JA 4XT6A 1LY3A 5HVEA 3QG2A 4KJLA 2DHFA 3OCHA 4QLEA 1DLRA 3NXYA 2FZJA 3QLWA 4H96A 1AOEA 4Q6AA 3EEJA 3FS6A 1DYIA 3RO9A 1SEJA 3IROA 4XE6X 4LEKX 4KFJA 4DFRA 1RX5A 2W3VA 4NX7A 3QFXA 2B3ZA 5ECCA 1DYJA 1DG5A 1KMVA 4QJZD 1M79A 1RC4A 4KL9A 1RX1A 5HI6A 3JSUA 5U26A 3SRWX 2GD9A 5U27A 1RX7A 3FQ0A 3I8AX 1DG7A 3S7AA 3F8YA 3FREX 4HOFA 1TDRA 1MVSA 4KD7A 3TQAA 3FYWX 4XECX 4G3MA 1DHJA 3FQFA 4P3RA 4EIZA 1RX6A 1LY4A 3JWFA 4QLFA 4PDJA 1OHKA 2W9TA 3E0BA 3JTWA 4KEBA 3JW3A 3Q1HA 2FZHA 3UM6A 1JOLA 3KGYA 3FRDX 1DLSA 3UM8A 4FHBA 1J3IA 1DR4A 7DFRA 1DYHA 2KGKA 3EELA 3QL0A 4KM2A 4XT5A 1AO8A 3IRMA 4IXED 4OSGA 3QGTA 3SQYX 4M7UA 3FRBX 1U70A 2ANQA 3D84X 3DL5A 1RF7A 3FL8A 4P66A 1DDRA 3K45A 1DR6A 4ELHA 3KY8A 4ECKA 3EEMA 3FY8X 4PSSA 1QZFA 4KAKA 4QI9A 2OBCA 3FQCA 1RB2A 3NZCX 1CD2A 5E8QA 2HM9A 1MVTA 3GHVA 3R33A 2XW7A 3NZ9X 2L28A 5HSRA 4QHVA 3QLYA 5HQZA 2LF1A 4RGCA 4DP3A 3NZDA 3TQ8A 4Q67A 2QK8A 1PD9A 2D5NA 5FDAA 3GI2A 4IXFX 5EAJA 1IA4A 3SH2A 1DDSA 3DFRA 4NX6A 4FGHA 4LAEX 4TU5X 2O7PA 3KJRA 4HOGA 2W3BA 4H98A 4X5IA 4PSYA 1AI9A 3DATA 1RA9A 4ELBA 4M7VA 4ELGA 1DHFA 5DXVA 4KJKA 3SRUX 1RH3A 2ITHA 4HA9A 4P3QA 1VJ3A 1S3UA 5HUIA 4DPDA 3FRAX 3FQVA 1DHIA 4OR7A 4X5HA 3NZBX 1OHJA 3SGYA 3GHWA 3IA4A 3EEKA 2FZIA 4EILA 1CZ3A 5CCCA 1U71A 1VDRA 1RG7A 3QYLA 4HA7A 4IXGX 3FY9X 1RX9A 3NXVA 1YHOA 2BL9A 1IA3A
chains in the Genus database with same CATH superfamily
3JWMA 1KMSA 3GYFA 3FL9A 2HXVA 3IX9A 4Q0DA 2BLCA 4XT4A 4LAGX 3CD2A 3FQZA 5HSUA 3QLXA 3ROAA 1HFQA 3SRSX 2HQPA 3CLBA 1IA2A 3F0SX 3INVA 2INQA 4EJ1A 1U72A 3SR5X 2G6VA 1HFPA 1RA1A 4G95A 1JOMA 2P4GA 3QLZA 2C2TA 4XT7A 3DGAA 1LUDA 4KYAA 2JYBA 2W9GA 1RA2A 4G8ZX 1S3YA 2W9SA 4PTHA 3K47A 5HF0X 1PDBA 3ZPGA 4KJJA 4DPHA 4P68A 4PTJA 1DYRA 3TQBA 4KY4A 3LG4A 1DR3A 1DR5A 3VCOA 1RD7A 3FYVX 1RX4A 2ZZAA 5CC9A 1IA1A 4M2XA 1J3JA 1DRFA 1DRAA 4LAHX 5HF2X 3S3VA 4ELEA 4DDRA 1KLKA 5HQYA 1RX3A 1PD8A 3DRCA 2W9HA 4KY8A 3NRRA 3NXXA 3DAUA 5HPBA 4KLXA 3F0XX 3TD8A 3ZPCA 5DFRA 2DRCA 3CL9A 1RA3A 1BZFA 3JVXA 3NZ6X 3OAFA 3EIGA 3K2HA 5HVBA 3TQ9A 5ECXA 1DR7A 3F0UX 3GHCA 4EIGA 3FQOA 4QLGA 5HT5A 4H95A 1RA8A 3DL6A 1DG8A 1HFRA 4GH8A 1DISA 4KBNA 3M08A 3QLRA 1DAJA 2CIGA 2W3MA 2BLAA 3JWCA 4FGGA 1DRBA 4CD2A 1S3VA 1M78A 1M7AA 4XRBA 3RG9A 1S3WA 3HBBA 3SA1A 3K74A 2OIPA 3UM5A 3SRRX 3IRNA 3EX8A 3F0QX 5HT4A 3KJSA 2C2SA 1D1GA 1E26A 3NXOA 4H97A 8DFRA 1RX2A 3S9UA 4ELFA 3N0HA 4M6JA 4X5FA 4PSTA 4X5GA 2W3WA 3I3RA 1ZDRA 5JA3A 4I1NA 3M09A 3DG8A 3F0VX 1DR2A 2BLBA 1DF7A 3NTZA 3F0BX 3SA2A 3NU0A 1DRHA 3QYOA 1JUVA 4Q0EA 3IA5A 1DREA 3CSEA 4KNEA 3JW5A 1BOZA 1RE7A 2H2QA 2D0KA 3NXTA 3F8ZA 3QLSA 4M6LA 1DIUA 2W3AA 3D80A 5JG0X 3SAIA 4XT8A 4I13A 3HJ3A 1DR1A 1RX8A 1J3KA 3SRQX 6DFRA 4HOEA 1RB3A 2ANOA 3NZAX 3NXRA 3QL3A 3KFYA 4M6KA 3F91A 4KM0A 4QJCA 3JWKA 2AZNA 3FRFX 2CD2A 3L3RA 4X5JA 4XT6A 1LY3A 5HVEA 3QG2A 4KJLA 2DHFA 3OCHA 4QLEA 1DLRA 3NXYA 2FZJA 3QLWA 4H96A 1AOEA 4Q6AA 3EEJA 3FS6A 1DYIA 3RO9A 1SEJA 3IROA 4XE6X 4LEKX 4KFJA 4DFRA 1RX5A 2W3VA 4NX7A 3QFXA 2B3ZA 5ECCA 1DYJA 1DG5A 1KMVA 4QJZD 1M79A 1RC4A 4KL9A 1RX1A 5HI6A 3JSUA 5U26A 3SRWX 2GD9A 5U27A 1RX7A 3FQ0A 3I8AX 1DG7A 3S7AA 3F8YA 3FREX 4HOFA 1TDRA 1MVSA 4KD7A 3TQAA 3FYWX 4XECX 4G3MA 1DHJA 3FQFA 4P3RA 4EIZA 1RX6A 1LY4A 3JWFA 4QLFA 4PDJA 1OHKA 2W9TA 3E0BA 3JTWA 4KEBA 3JW3A 3Q1HA 2FZHA 3UM6A 1JOLA 3KGYA 3FRDX 1DLSA 3UM8A 4FHBA 1J3IA 1DR4A 7DFRA 1DYHA 2KGKA 3EELA 3QL0A 4KM2A 4XT5A 1AO8A 3IRMA 4IXED 4OSGA 3QGTA 3SQYX 4M7UA 3FRBX 1U70A 2ANQA 3D84X 3DL5A 1RF7A 3FL8A 4P66A 1DDRA 3K45A 1DR6A 4ELHA 3KY8A 4ECKA 3EEMA 3FY8X 4PSSA 1QZFA 4KAKA 4QI9A 2OBCA 3FQCA 1RB2A 3NZCX 1CD2A 5E8QA 2HM9A 1MVTA 3GHVA 3R33A 2XW7A 3NZ9X 2L28A 5HSRA 4QHVA 3QLYA 5HQZA 2LF1A 4RGCA 4DP3A 3NZDA 3TQ8A 4Q67A 2QK8A 1PD9A 2D5NA 5FDAA 3GI2A 4IXFX 5EAJA 1IA4A 3SH2A 1DDSA 3DFRA 4NX6A 4FGHA 4LAEX 4TU5X 2O7PA 3KJRA 4HOGA 2W3BA 4H98A 4X5IA 4PSYA 1AI9A 3DATA 1RA9A 4ELBA 4M7VA 4ELGA 1DHFA 5DXVA 4KJKA 3SRUX 1RH3A 2ITHA 4HA9A 4P3QA 1VJ3A 1S3UA 5HUIA 4DPDA 3FRAX 3FQVA 1DHIA 4OR7A 4X5HA 3NZBX 1OHJA 3SGYA 3GHWA 3IA4A 3EEKA 2FZIA 4EILA 1CZ3A 5CCCA 1U71A 1VDRA 1RG7A 3QYLA 4HA7A 4IXGX 3FY9X 1RX9A 3NXVA 1YHOA 2BL9A 1IA3A
chains in the Genus database with same CATH topology
3JWMA 1KMSA 3GYFA 3FL9A 2HXVA 3IX9A 4Q0DA 2BLCA 4XT4A 4LAGX 3CD2A 3FQZA 5HSUA 3QLXA 3ROAA 1HFQA 3SRSX 2HQPA 3CLBA 1IA2A 3F0SX 3INVA 2INQA 4EJ1A 1U72A 3SR5X 2G6VA 1HFPA 1RA1A 4G95A 1JOMA 2P4GA 3QLZA 2C2TA 4XT7A 3DGAA 1LUDA 4KYAA 2JYBA 2W9GA 1RA2A 4G8ZX 1S3YA 2W9SA 4PTHA 3K47A 5HF0X 1PDBA 3ZPGA 4KJJA 4DPHA 4P68A 4PTJA 1DYRA 3TQBA 4KY4A 3LG4A 1DR3A 1DR5A 3VCOA 1RD7A 3FYVX 1RX4A 2ZZAA 5CC9A 1IA1A 4M2XA 1J3JA 1DRFA 1DRAA 4LAHX 5HF2X 3S3VA 4ELEA 4DDRA 1KLKA 5HQYA 1RX3A 1PD8A 3DRCA 2W9HA 4KY8A 3NRRA 3NXXA 3DAUA 5HPBA 4KLXA 3F0XX 3TD8A 3ZPCA 5DFRA 2DRCA 3CL9A 1RA3A 1BZFA 3JVXA 3NZ6X 3OAFA 3EIGA 3K2HA 5HVBA 3TQ9A 5ECXA 1DR7A 3F0UX 3GHCA 4EIGA 3FQOA 4QLGA 5HT5A 4H95A 1RA8A 3DL6A 1DG8A 1HFRA 4GH8A 1DISA 4KBNA 3M08A 3QLRA 1DAJA 2CIGA 2W3MA 2BLAA 3JWCA 4FGGA 1DRBA 4CD2A 1S3VA 1M78A 1M7AA 4XRBA 3RG9A 1S3WA 3HBBA 3SA1A 3K74A 2OIPA 3UM5A 3SRRX 3IRNA 3EX8A 3F0QX 5HT4A 3KJSA 2C2SA 1D1GA 1E26A 3NXOA 4H97A 8DFRA 1RX2A 3S9UA 4ELFA 3N0HA 4M6JA 4X5FA 4PSTA 4X5GA 2W3WA 3I3RA 1ZDRA 5JA3A 4I1NA 3M09A 3DG8A 3F0VX 1DR2A 2BLBA 1DF7A 3NTZA 3F0BX 3SA2A 3NU0A 1DRHA 3QYOA 1JUVA 4Q0EA 3IA5A 1DREA 3CSEA 4KNEA 3JW5A 1BOZA 1RE7A 2H2QA 2D0KA 3NXTA 3F8ZA 3QLSA 4M6LA 1DIUA 2W3AA 3D80A 5JG0X 3SAIA 4XT8A 4I13A 3HJ3A 1DR1A 1RX8A 1J3KA 3SRQX 6DFRA 4HOEA 1RB3A 2ANOA 3NZAX 3NXRA 3QL3A 3KFYA 4M6KA 3F91A 4KM0A 4QJCA 3JWKA 2AZNA 3FRFX 2CD2A 3L3RA 4X5JA 4XT6A 1LY3A 5HVEA 3QG2A 4KJLA 2DHFA 3OCHA 4QLEA 1DLRA 3NXYA 2FZJA 3QLWA 4H96A 1AOEA 4Q6AA 3EEJA 3FS6A 1DYIA 3RO9A 1SEJA 3IROA 4XE6X 4LEKX 4KFJA 4DFRA 1RX5A 2W3VA 4NX7A 3QFXA 2B3ZA 5ECCA 1DYJA 1DG5A 1KMVA 4QJZD 1M79A 1RC4A 4KL9A 1RX1A 5HI6A 3JSUA 5U26A 3SRWX 2GD9A 5U27A 1RX7A 3FQ0A 3I8AX 1DG7A 3S7AA 3F8YA 3FREX 4HOFA 1TDRA 1MVSA 4KD7A 3TQAA 3FYWX 4XECX 4G3MA 1DHJA 3FQFA 4P3RA 4EIZA 1RX6A 1LY4A 3JWFA 4QLFA 4PDJA 1OHKA 2W9TA 3E0BA 3JTWA 4KEBA 3JW3A 3Q1HA 2FZHA 3UM6A 1JOLA 3KGYA 3FRDX 1DLSA 3UM8A 4FHBA 1J3IA 1DR4A 7DFRA 1DYHA 2KGKA 3EELA 3QL0A 4KM2A 4XT5A 1AO8A 3IRMA 4IXED 4OSGA 3QGTA 3SQYX 4M7UA 3FRBX 1U70A 2ANQA 3D84X 3DL5A 1RF7A 3FL8A 4P66A 1DDRA 3K45A 1DR6A 4ELHA 3KY8A 4ECKA 3EEMA 3FY8X 4PSSA 1QZFA 4KAKA 4QI9A 2OBCA 3FQCA 1RB2A 3NZCX 1CD2A 5E8QA 2HM9A 1MVTA 3GHVA 3R33A 2XW7A 3NZ9X 2L28A 5HSRA 4QHVA 3QLYA 5HQZA 2LF1A 4RGCA 4DP3A 3NZDA 3TQ8A 4Q67A 2QK8A 1PD9A 2D5NA 5FDAA 3GI2A 4IXFX 5EAJA 1IA4A 3SH2A 1DDSA 3DFRA 4NX6A 4FGHA 4LAEX 4TU5X 2O7PA 3KJRA 4HOGA 2W3BA 4H98A 4X5IA 4PSYA 1AI9A 3DATA 1RA9A 4ELBA 4M7VA 4ELGA 1DHFA 5DXVA 4KJKA 3SRUX 1RH3A 2ITHA 4HA9A 4P3QA 1VJ3A 1S3UA 5HUIA 4DPDA 3FRAX 3FQVA 1DHIA 4OR7A 4X5HA 3NZBX 1OHJA 3SGYA 3GHWA 3IA4A 3EEKA 2FZIA 4EILA 1CZ3A 5CCCA 1U71A 1VDRA 1RG7A 3QYLA 4HA7A 4IXGX 3FY9X 1RX9A 3NXVA 1YHOA 2BL9A 1IA3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JWM A;  1KMS A;  3GYF A;  3FL9 A;  2HXV A;  3IX9 A;  4Q0D A;  2BLC A;  4XT4 A;  4LAG X;  3CD2 A;  3FQZ A;  5HSU A;  3QLX A;  3ROA A;  1HFQ A;  3SRS X;  2HQP A;  3CLB A;  1IA2 A;  3F0S X;  3INV A;  2INQ A;  4EJ1 A;  1U72 A;  3SR5 X;  2G6V A;  1HFP A;  1RA1 A;  4G95 A;  1JOM A;  2P4G A;  3QLZ A;  2C2T A;  4XT7 A;  3DGA A;  1LUD A;  4KYA A;  2JYB A;  2W9G A;  1RA2 A;  4G8Z X;  1S3Y A;  2W9S A;  4PTH A;  3K47 A;  5HF0 X;  1PDB A;  3ZPG A;  4KJJ A;  4DPH A;  4P68 A;  4PTJ A;  1DYR A;  3TQB A;  4KY4 A;  3LG4 A;  1DR3 A;  1DR5 A;  3VCO A;  1RD7 A;  3FYV X;  1RX4 A;  2ZZA A;  5CC9 A;  1IA1 A;  4M2X A;  1J3J A;  1DRF A;  1DRA A;  4LAH X;  5HF2 X;  3S3V A;  4ELE A;  4DDR A;  1KLK A;  5HQY A;  1RX3 A;  1PD8 A;  3DRC A;  2W9H A;  4KY8 A;  3NRR A;  3NXX A;  3DAU A;  5HPB A;  4KLX A;  3F0X X;  3TD8 A;  3ZPC A;  5DFR A;  2DRC A;  3CL9 A;  1RA3 A;  1BZF A;  3JVX A;  3NZ6 X;  3OAF A;  3EIG A;  3K2H A;  5HVB A;  3TQ9 A;  5ECX A;  1DR7 A;  3F0U X;  3GHC A;  4EIG A;  3FQO A;  4QLG A;  5HT5 A;  4H95 A;  1RA8 A;  3DL6 A;  1DG8 A;  1HFR A;  4GH8 A;  1DIS A;  4KBN A;  3M08 A;  3QLR A;  1DAJ A;  2CIG A;  2W3M A;  2BLA A;  3JWC A;  4FGG A;  1DRB A;  4CD2 A;  1S3V A;  1M78 A;  1M7A A;  4XRB A;  3RG9 A;  1S3W A;  3HBB A;  3SA1 A;  3K74 A;  2OIP A;  3UM5 A;  3SRR X;  3IRN A;  3EX8 A;  3F0Q X;  5HT4 A;  3KJS A;  2C2S A;  1D1G A;  1E26 A;  3NXO A;  4H97 A;  8DFR A;  1RX2 A;  3S9U A;  4ELF A;  3N0H A;  4M6J A;  4X5F A;  4PST A;  4X5G A;  2W3W A;  3I3R A;  1ZDR A;  5JA3 A;  4I1N A;  3M09 A;  3DG8 A;  3F0V X;  1DR2 A;  2BLB A;  1DF7 A;  3NTZ A;  3F0B X;  3SA2 A;  3NU0 A;  1DRH A;  3QYO A;  1JUV A;  4Q0E A;  3IA5 A;  1DRE A;  3CSE A;  4KNE A;  3JW5 A;  1BOZ A;  1RE7 A;  2H2Q A;  2D0K A;  3NXT A;  3F8Z A;  3QLS A;  4M6L A;  1DIU A;  2W3A A;  3D80 A;  5JG0 X;  3SAI A;  4XT8 A;  4I13 A;  3HJ3 A;  1DR1 A;  1RX8 A;  1J3K A;  3SRQ X;  6DFR A;  4HOE A;  1RB3 A;  2ANO A;  3NZA X;  3NXR A;  3QL3 A;  3KFY A;  4M6K A;  3F91 A;  4KM0 A;  4QJC A;  3JWK A;  2AZN A;  3FRF X;  2CD2 A;  3L3R A;  4X5J A;  4XT6 A;  1LY3 A;  5HVE A;  3QG2 A;  4KJL A;  2DHF A;  3OCH A;  4QLE A;  1DLR A;  3NXY A;  2FZJ A;  3QLW A;  4H96 A;  1AOE A;  4Q6A A;  3EEJ A;  3FS6 A;  1DYI A;  3RO9 A;  1SEJ A;  3IRO A;  4XE6 X;  4LEK X;  4KFJ A;  4DFR A;  1RX5 A;  2W3V A;  4NX7 A;  3QFX A;  2B3Z A;  5ECC A;  1DYJ A;  1DG5 A;  1KMV A;  4QJZ D;  1M79 A;  1RC4 A;  4KL9 A;  1RX1 A;  5HI6 A;  3JSU A;  5U26 A;  3SRW X;  2GD9 A;  5U27 A;  1RX7 A;  3FQ0 A;  3I8A X;  1DG7 A;  3S7A A;  3F8Y A;  3FRE X;  4HOF A;  1TDR A;  1MVS A;  4KD7 A;  3TQA A;  3FYW X;  4XEC X;  4G3M A;  1DHJ A;  3FQF A;  4P3R A;  4EIZ A;  1RX6 A;  1LY4 A;  3JWF A;  4QLF A;  4PDJ A;  1OHK A;  2W9T A;  3E0B A;  3JTW A;  4KEB A;  3JW3 A;  3Q1H A;  2FZH A;  3UM6 A;  1JOL A;  3KGY A;  3FRD X;  1DLS A;  3UM8 A;  4FHB A;  1J3I A;  1DR4 A;  7DFR A;  1DYH A;  2KGK A;  3EEL A;  3QL0 A;  4KM2 A;  4XT5 A;  1AO8 A;  3IRM A;  4IXE D;  4OSG A;  3QGT A;  3SQY X;  4M7U A;  3FRB X;  1U70 A;  2ANQ A;  3D84 X;  3DL5 A;  1RF7 A;  3FL8 A;  4P66 A;  1DDR A;  3K45 A;  1DR6 A;  4ELH A;  3KY8 A;  4ECK A;  3EEM A;  3FY8 X;  4PSS A;  1QZF A;  4KAK A;  4QI9 A;  2OBC A;  3FQC A;  1RB2 A;  3NZC X;  1CD2 A;  5E8Q A;  2HM9 A;  1MVT A;  3GHV A;  3R33 A;  2XW7 A;  3NZ9 X;  2L28 A;  5HSR A;  4QHV A;  3QLY A;  5HQZ A;  2LF1 A;  4RGC A;  4DP3 A;  3NZD A;  3TQ8 A;  4Q67 A;  2QK8 A;  1PD9 A;  2D5N A;  5FDA A;  3GI2 A;  4IXF X;  5EAJ A;  1IA4 A;  3SH2 A;  1DDS A;  3DFR A;  4NX6 A;  4FGH A;  4LAE X;  4TU5 X;  2O7P A;  3KJR A;  4HOG A;  2W3B A;  4H98 A;  4X5I A;  4PSY A;  1AI9 A;  3DAT A;  1RA9 A;  4ELB A;  4M7V A;  4ELG A;  1DHF A;  5DXV A;  4KJK A;  3SRU X;  1RH3 A;  2ITH A;  4HA9 A;  4P3Q A;  1VJ3 A;  1S3U A;  5HUI A;  4DPD A;  3FRA X;  3FQV A;  1DHI A;  4OR7 A;  4X5H A;  3NZB X;  1OHJ A;  3SGY A;  3GHW A;  3IA4 A;  3EEK A;  2FZI A;  4EIL A;  1CZ3 A;  5CCC A;  1U71 A;  1VDR A;  1RG7 A;  3QYL A;  4HA7 A;  4IXG X;  3FY9 X;  1RX9 A;  3NXV A;  1YHO A;  2BL9 A;  1IA3 A; 
#chains in the Genus database with same CATH topology
 3JWM A;  1KMS A;  3GYF A;  3FL9 A;  2HXV A;  3IX9 A;  4Q0D A;  2BLC A;  4XT4 A;  4LAG X;  3CD2 A;  3FQZ A;  5HSU A;  3QLX A;  3ROA A;  1HFQ A;  3SRS X;  2HQP A;  3CLB A;  1IA2 A;  3F0S X;  3INV A;  2INQ A;  4EJ1 A;  1U72 A;  3SR5 X;  2G6V A;  1HFP A;  1RA1 A;  4G95 A;  1JOM A;  2P4G A;  3QLZ A;  2C2T A;  4XT7 A;  3DGA A;  1LUD A;  4KYA A;  2JYB A;  2W9G A;  1RA2 A;  4G8Z X;  1S3Y A;  2W9S A;  4PTH A;  3K47 A;  5HF0 X;  1PDB A;  3ZPG A;  4KJJ A;  4DPH A;  4P68 A;  4PTJ A;  1DYR A;  3TQB A;  4KY4 A;  3LG4 A;  1DR3 A;  1DR5 A;  3VCO A;  1RD7 A;  3FYV X;  1RX4 A;  2ZZA A;  5CC9 A;  1IA1 A;  4M2X A;  1J3J A;  1DRF A;  1DRA A;  4LAH X;  5HF2 X;  3S3V A;  4ELE A;  4DDR A;  1KLK A;  5HQY A;  1RX3 A;  1PD8 A;  3DRC A;  2W9H A;  4KY8 A;  3NRR A;  3NXX A;  3DAU A;  5HPB A;  4KLX A;  3F0X X;  3TD8 A;  3ZPC A;  5DFR A;  2DRC A;  3CL9 A;  1RA3 A;  1BZF A;  3JVX A;  3NZ6 X;  3OAF A;  3EIG A;  3K2H A;  5HVB A;  3TQ9 A;  5ECX A;  1DR7 A;  3F0U X;  3GHC A;  4EIG A;  3FQO A;  4QLG A;  5HT5 A;  4H95 A;  1RA8 A;  3DL6 A;  1DG8 A;  1HFR A;  4GH8 A;  1DIS A;  4KBN A;  3M08 A;  3QLR A;  1DAJ A;  2CIG A;  2W3M A;  2BLA A;  3JWC A;  4FGG A;  1DRB A;  4CD2 A;  1S3V A;  1M78 A;  1M7A A;  4XRB A;  3RG9 A;  1S3W A;  3HBB A;  3SA1 A;  3K74 A;  2OIP A;  3UM5 A;  3SRR X;  3IRN A;  3EX8 A;  3F0Q X;  5HT4 A;  3KJS A;  2C2S A;  1D1G A;  1E26 A;  3NXO A;  4H97 A;  8DFR A;  1RX2 A;  3S9U A;  4ELF A;  3N0H A;  4M6J A;  4X5F A;  4PST A;  4X5G A;  2W3W A;  3I3R A;  1ZDR A;  5JA3 A;  4I1N A;  3M09 A;  3DG8 A;  3F0V X;  1DR2 A;  2BLB A;  1DF7 A;  3NTZ A;  3F0B X;  3SA2 A;  3NU0 A;  1DRH A;  3QYO A;  1JUV A;  4Q0E A;  3IA5 A;  1DRE A;  3CSE A;  4KNE A;  3JW5 A;  1BOZ A;  1RE7 A;  2H2Q A;  2D0K A;  3NXT A;  3F8Z A;  3QLS A;  4M6L A;  1DIU A;  2W3A A;  3D80 A;  5JG0 X;  3SAI A;  4XT8 A;  4I13 A;  3HJ3 A;  1DR1 A;  1RX8 A;  1J3K A;  3SRQ X;  6DFR A;  4HOE A;  1RB3 A;  2ANO A;  3NZA X;  3NXR A;  3QL3 A;  3KFY A;  4M6K A;  3F91 A;  4KM0 A;  4QJC A;  3JWK A;  2AZN A;  3FRF X;  2CD2 A;  3L3R A;  4X5J A;  4XT6 A;  1LY3 A;  5HVE A;  3QG2 A;  4KJL A;  2DHF A;  3OCH A;  4QLE A;  1DLR A;  3NXY A;  2FZJ A;  3QLW A;  4H96 A;  1AOE A;  4Q6A A;  3EEJ A;  3FS6 A;  1DYI A;  3RO9 A;  1SEJ A;  3IRO A;  4XE6 X;  4LEK X;  4KFJ A;  4DFR A;  1RX5 A;  2W3V A;  4NX7 A;  3QFX A;  2B3Z A;  5ECC A;  1DYJ A;  1DG5 A;  1KMV A;  4QJZ D;  1M79 A;  1RC4 A;  4KL9 A;  1RX1 A;  5HI6 A;  3JSU A;  5U26 A;  3SRW X;  2GD9 A;  5U27 A;  1RX7 A;  3FQ0 A;  3I8A X;  1DG7 A;  3S7A A;  3F8Y A;  3FRE X;  4HOF A;  1TDR A;  1MVS A;  4KD7 A;  3TQA A;  3FYW X;  4XEC X;  4G3M A;  1DHJ A;  3FQF A;  4P3R A;  4EIZ A;  1RX6 A;  1LY4 A;  3JWF A;  4QLF A;  4PDJ A;  1OHK A;  2W9T A;  3E0B A;  3JTW A;  4KEB A;  3JW3 A;  3Q1H A;  2FZH A;  3UM6 A;  1JOL A;  3KGY A;  3FRD X;  1DLS A;  3UM8 A;  4FHB A;  1J3I A;  1DR4 A;  7DFR A;  1DYH A;  2KGK A;  3EEL A;  3QL0 A;  4KM2 A;  4XT5 A;  1AO8 A;  3IRM A;  4IXE D;  4OSG A;  3QGT A;  3SQY X;  4M7U A;  3FRB X;  1U70 A;  2ANQ A;  3D84 X;  3DL5 A;  1RF7 A;  3FL8 A;  4P66 A;  1DDR A;  3K45 A;  1DR6 A;  4ELH A;  3KY8 A;  4ECK A;  3EEM A;  3FY8 X;  4PSS A;  1QZF A;  4KAK A;  4QI9 A;  2OBC A;  3FQC A;  1RB2 A;  3NZC X;  1CD2 A;  5E8Q A;  2HM9 A;  1MVT A;  3GHV A;  3R33 A;  2XW7 A;  3NZ9 X;  2L28 A;  5HSR A;  4QHV A;  3QLY A;  5HQZ A;  2LF1 A;  4RGC A;  4DP3 A;  3NZD A;  3TQ8 A;  4Q67 A;  2QK8 A;  1PD9 A;  2D5N A;  5FDA A;  3GI2 A;  4IXF X;  5EAJ A;  1IA4 A;  3SH2 A;  1DDS A;  3DFR A;  4NX6 A;  4FGH A;  4LAE X;  4TU5 X;  2O7P A;  3KJR A;  4HOG A;  2W3B A;  4H98 A;  4X5I A;  4PSY A;  1AI9 A;  3DAT A;  1RA9 A;  4ELB A;  4M7V A;  4ELG A;  1DHF A;  5DXV A;  4KJK A;  3SRU X;  1RH3 A;  2ITH A;  4HA9 A;  4P3Q A;  1VJ3 A;  1S3U A;  5HUI A;  4DPD A;  3FRA X;  3FQV A;  1DHI A;  4OR7 A;  4X5H A;  3NZB X;  1OHJ A;  3SGY A;  3GHW A;  3IA4 A;  3EEK A;  2FZI A;  4EIL A;  1CZ3 A;  5CCC A;  1U71 A;  1VDR A;  1RG7 A;  3QYL A;  4HA7 A;  4IXG X;  3FY9 X;  1RX9 A;  3NXV A;  1YHO A;  2BL9 A;  1IA3 A; 
#chains in the Genus database with same CATH homology
 3JWM A;  1KMS A;  3GYF A;  3FL9 A;  2HXV A;  3IX9 A;  4Q0D A;  2BLC A;  4XT4 A;  4LAG X;  3CD2 A;  3FQZ A;  5HSU A;  3QLX A;  3ROA A;  1HFQ A;  3SRS X;  2HQP A;  3CLB A;  1IA2 A;  3F0S X;  3INV A;  2INQ A;  4EJ1 A;  1U72 A;  3SR5 X;  2G6V A;  1HFP A;  1RA1 A;  4G95 A;  1JOM A;  2P4G A;  3QLZ A;  2C2T A;  4XT7 A;  3DGA A;  1LUD A;  4KYA A;  2JYB A;  2W9G A;  1RA2 A;  4G8Z X;  1S3Y A;  2W9S A;  4PTH A;  3K47 A;  5HF0 X;  1PDB A;  3ZPG A;  4KJJ A;  4DPH A;  4P68 A;  4PTJ A;  1DYR A;  3TQB A;  4KY4 A;  3LG4 A;  1DR3 A;  1DR5 A;  3VCO A;  1RD7 A;  3FYV X;  1RX4 A;  2ZZA A;  5CC9 A;  1IA1 A;  4M2X A;  1J3J A;  1DRF A;  1DRA A;  4LAH X;  5HF2 X;  3S3V A;  4ELE A;  4DDR A;  1KLK A;  5HQY A;  1RX3 A;  1PD8 A;  3DRC A;  2W9H A;  4KY8 A;  3NRR A;  3NXX A;  3DAU A;  5HPB A;  4KLX A;  3F0X X;  3TD8 A;  3ZPC A;  5DFR A;  2DRC A;  3CL9 A;  1RA3 A;  1BZF A;  3JVX A;  3NZ6 X;  3OAF A;  3EIG A;  3K2H A;  5HVB A;  3TQ9 A;  5ECX A;  1DR7 A;  3F0U X;  3GHC A;  4EIG A;  3FQO A;  4QLG A;  5HT5 A;  4H95 A;  1RA8 A;  3DL6 A;  1DG8 A;  1HFR A;  4GH8 A;  1DIS A;  4KBN A;  3M08 A;  3QLR A;  1DAJ A;  2CIG A;  2W3M A;  2BLA A;  3JWC A;  4FGG A;  1DRB A;  4CD2 A;  1S3V A;  1M78 A;  1M7A A;  4XRB A;  3RG9 A;  1S3W A;  3HBB A;  3SA1 A;  3K74 A;  2OIP A;  3UM5 A;  3SRR X;  3IRN A;  3EX8 A;  3F0Q X;  5HT4 A;  3KJS A;  2C2S A;  1D1G A;  1E26 A;  3NXO A;  4H97 A;  8DFR A;  1RX2 A;  3S9U A;  4ELF A;  3N0H A;  4M6J A;  4X5F A;  4PST A;  4X5G A;  2W3W A;  3I3R A;  1ZDR A;  5JA3 A;  4I1N A;  3M09 A;  3DG8 A;  3F0V X;  1DR2 A;  2BLB A;  1DF7 A;  3NTZ A;  3F0B X;  3SA2 A;  3NU0 A;  1DRH A;  3QYO A;  1JUV A;  4Q0E A;  3IA5 A;  1DRE A;  3CSE A;  4KNE A;  3JW5 A;  1BOZ A;  1RE7 A;  2H2Q A;  2D0K A;  3NXT A;  3F8Z A;  3QLS A;  4M6L A;  1DIU A;  2W3A A;  3D80 A;  5JG0 X;  3SAI A;  4XT8 A;  4I13 A;  3HJ3 A;  1DR1 A;  1RX8 A;  1J3K A;  3SRQ X;  6DFR A;  4HOE A;  1RB3 A;  2ANO A;  3NZA X;  3NXR A;  3QL3 A;  3KFY A;  4M6K A;  3F91 A;  4KM0 A;  4QJC A;  3JWK A;  2AZN A;  3FRF X;  2CD2 A;  3L3R A;  4X5J A;  4XT6 A;  1LY3 A;  5HVE A;  3QG2 A;  4KJL A;  2DHF A;  3OCH A;  4QLE A;  1DLR A;  3NXY A;  2FZJ A;  3QLW A;  4H96 A;  1AOE A;  4Q6A A;  3EEJ A;  3FS6 A;  1DYI A;  3RO9 A;  1SEJ A;  3IRO A;  4XE6 X;  4LEK X;  4KFJ A;  4DFR A;  1RX5 A;  2W3V A;  4NX7 A;  3QFX A;  2B3Z A;  5ECC A;  1DYJ A;  1DG5 A;  1KMV A;  4QJZ D;  1M79 A;  1RC4 A;  4KL9 A;  1RX1 A;  5HI6 A;  3JSU A;  5U26 A;  3SRW X;  2GD9 A;  5U27 A;  1RX7 A;  3FQ0 A;  3I8A X;  1DG7 A;  3S7A A;  3F8Y A;  3FRE X;  4HOF A;  1TDR A;  1MVS A;  4KD7 A;  3TQA A;  3FYW X;  4XEC X;  4G3M A;  1DHJ A;  3FQF A;  4P3R A;  4EIZ A;  1RX6 A;  1LY4 A;  3JWF A;  4QLF A;  4PDJ A;  1OHK A;  2W9T A;  3E0B A;  3JTW A;  4KEB A;  3JW3 A;  3Q1H A;  2FZH A;  3UM6 A;  1JOL A;  3KGY A;  3FRD X;  1DLS A;  3UM8 A;  4FHB A;  1J3I A;  1DR4 A;  7DFR A;  1DYH A;  2KGK A;  3EEL A;  3QL0 A;  4KM2 A;  4XT5 A;  1AO8 A;  3IRM A;  4IXE D;  4OSG A;  3QGT A;  3SQY X;  4M7U A;  3FRB X;  1U70 A;  2ANQ A;  3D84 X;  3DL5 A;  1RF7 A;  3FL8 A;  4P66 A;  1DDR A;  3K45 A;  1DR6 A;  4ELH A;  3KY8 A;  4ECK A;  3EEM A;  3FY8 X;  4PSS A;  1QZF A;  4KAK A;  4QI9 A;  2OBC A;  3FQC A;  1RB2 A;  3NZC X;  1CD2 A;  5E8Q A;  2HM9 A;  1MVT A;  3GHV A;  3R33 A;  2XW7 A;  3NZ9 X;  2L28 A;  5HSR A;  4QHV A;  3QLY A;  5HQZ A;  2LF1 A;  4RGC A;  4DP3 A;  3NZD A;  3TQ8 A;  4Q67 A;  2QK8 A;  1PD9 A;  2D5N A;  5FDA A;  3GI2 A;  4IXF X;  5EAJ A;  1IA4 A;  3SH2 A;  1DDS A;  3DFR A;  4NX6 A;  4FGH A;  4LAE X;  4TU5 X;  2O7P A;  3KJR A;  4HOG A;  2W3B A;  4H98 A;  4X5I A;  4PSY A;  1AI9 A;  3DAT A;  1RA9 A;  4ELB A;  4M7V A;  4ELG A;  1DHF A;  5DXV A;  4KJK A;  3SRU X;  1RH3 A;  2ITH A;  4HA9 A;  4P3Q A;  1VJ3 A;  1S3U A;  5HUI A;  4DPD A;  3FRA X;  3FQV A;  1DHI A;  4OR7 A;  4X5H A;  3NZB X;  1OHJ A;  3SGY A;  3GHW A;  3IA4 A;  3EEK A;  2FZI A;  4EIL A;  1CZ3 A;  5CCC A;  1U71 A;  1VDR A;  1RG7 A;  3QYL A;  4HA7 A;  4IXG X;  3FY9 X;  1RX9 A;  3NXV A;  1YHO A;  2BL9 A;  1IA3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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