3FQCA

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (ucp115a)
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fqcA00
1RX6A 4EILA 3SAIA 3JWMA 4HOGA 3INVA 1RD7A 2DHFA 4H98A 3SR5X 3TQAA 3SRRX 4M6KA 4DPHA 4ECKA 1TDRA 3KFYA 3QLRA 3FL8A 3SQYX 3GI2A 3KY8A 4H95A 1RX9A 4NX6A 3TD8A 3QLYA 4QLEA 1HFQA 1DRFA 1DRHA 5HT5A 3NZAX 2FZIA 3FL9A 3EEKA 3NXVA 1RC4A 1S3WA 1DG5A 2HM9A 1LY4A 3JWKA 4LAEX 2P4GA 4ELHA 2HXVA 1DR6A 3CD2A 1DREA 4KD7A 1KMVA 3KJRA 3SA2A 3M09A 1LUDA 2LF1A 3NXYA 1J3IA 3NXTA 1S3VA 5HVBA 3UM8A 3E0BA 4KY4A 4EIZA 4OR7A 2G6VA 4XT6A 3QLSA 3IA5A 4KM0A 1DYHA 1LY3A 2DRCA 1AI9A 3F0XX 4PSSA 4KEBA 3SA1A 3FRDX 4KJKA 1CZ3A 1AO8A 1DR4A 3SH2A 3NXXA 4X5FA 1J3JA 4ELGA 4M6JA 1RA2A 4KLXA 3FQCA 2W3WA 1AOEA 4FHBA 1RB3A 4XT5A 5JA3A 1RB2A 4QJCA 3N0HA 4P68A 2L28A 1CD2A 3SRQX 1RA3A 3F0UX 1PD8A 2ANQA 1RX7A 3S3VA 2W3AA 3QL3A 3KJSA 3SRWX 1DDRA 4FGHA 3CL9A 3F8YA 4KJJA 2CIGA 2KGKA 3RO9A 5ECCA 3TQBA 1J3KA 1DYIA 1KMSA 1DR3A 5HSUA 1VJ3A 5E8QA 1RE7A 1DG7A 3GYFA 1JOMA 2D5NA 3FRAX 4KY8A 3K45A 2ANOA 3JTWA 1KLKA 3GHWA 4KFJA 3FY9X 5HQZA 3NZ9X 4XE6X 3EELA 1M78A 5HSRA 1U71A 2ZZAA 3LG4A 3CSEA 4KAKA 1S3YA 3FY8X 4ELFA 4X5HA 3M08A 3HBBA 3QGTA 4IXFX 2HQPA 1PD9A 3GHVA 1ZDRA 2BL9A 4DPDA 2OBCA 3JWCA 4LAHX 1S3UA 4G8ZX 2CD2A 4KNEA 1DHJA 3GHCA 2B3ZA 5HT4A 4G95A 3QYLA 3IA4A 4LEKX 1DRBA 2XW7A 3UM6A 1VDRA 1IA2A 4G3MA 2INQA 4H96A 4H97A 3OCHA 3QL0A 4QHVA 1DLSA 1BOZA 2W9HA 4RGCA 4QJZD 2W9GA 2W9TA 1RH3A 1QZFA 1DDSA 2FZJA 4HOEA 3NXRA 3CLBA 2W3MA 4X5IA 2QK8A 4XT8A 1RF7A 4ELBA 3K74A 3DRCA 1U72A 1DHIA 1M7AA 3FQOA 4PTJA 3KGYA 1HFRA 3FREX 3FYWX 4P3RA 3R33A 1M79A 2BLCA 5FDAA 4XT7A 4OSGA 3JW3A 3S9UA 1RA1A 3L3RA 3NZDA 3ROAA 3NZ6X 1RA8A 4IXED 1E26A 3DGAA 3NZBX 3F0BX 2BLAA 3SRSX 3IROA 3TQ9A 3FRBX 1DIUA 2BLBA 4TU5X 1IA3A 4M7VA 1DISA 3EX8A 4HOFA 4EIGA 4KL9A 4M7UA 4GH8A 3JW5A 3QLZA 5U27A 3NZCX 5HQYA 4QI9A 3NU0A 4P66A 2OIPA 1MVTA 5HUIA 4NX7A 4FGGA 2H2QA 2FZHA 3JSUA 1RX4A 1RX8A 1U70A 1D1GA 1RX1A 4DDRA 4ELEA 5HPBA 3DAUA 4M2XA 6DFRA 1DRAA 5HF2X 3F0QX 3FS6A 3FQ0A 4Q0DA 2JYBA 3F0SX 3Q1HA 5EAJA 4CD2A 1RX5A 1IA1A 3D84X 1SEJA 3QLXA 3NRRA 5DFRA 3DL6A 4XECX 3IRMA 3K47A 4HA7A 4I13A 5DXVA 4PTHA 4XRBA 4QLFA 4KYAA 4KJLA 3DFRA 3UM5A 5HVEA 5CCCA 3OAFA 2GD9A 3F8ZA 4I1NA 1DHFA 1RG7A 2ITHA 1RA9A 2W3VA 8DFRA 5JG0X 1PDBA 4PDJA 3TQ8A 1OHKA 3EEMA 4Q0EA 4KBNA 4EJ1A 3K2HA 1DR5A 3NTZA 3FYVX 3VCOA 1HFPA 4PSYA 3ZPCA 3IX9A 3F0VX 7DFRA 3QLWA 3DG8A 4X5JA 1JUVA 3QYOA 3ZPGA 1DG8A 2W9SA 4HA9A 1DLRA 3EEJA 4PSTA 3S7AA 3DL5A 3D80A 4Q6AA 3FQVA 5HF0X 3NXOA 1DR2A 3HJ3A 3I3RA 2W3BA 3F91A 2AZNA 4KM2A 3DATA 3FQFA 3JVXA 4LAGX 1DR7A 3IRNA 4Q67A 5ECXA 1RX2A 3QG2A 4X5GA 4P3QA 4M6LA 3FRFX 3JWFA 5U26A 5CC9A 3SRUX 1DF7A 1MVSA 3EIGA 3RG9A 5HI6A 3QFXA 1IA4A 2D0KA 1RX3A 4DFRA 1DYJA 2O7PA 3I8AX 4XT4A 2C2TA 3FQZA 1YHOA 4IXGX 2C2SA 3SGYA 1OHJA 4DP3A 1JOLA 4QLGA 1DR1A 1DYRA 1BZFA 1DAJA
chains in the Genus database with same CATH superfamily
1RX6A 4EILA 3SAIA 3JWMA 4HOGA 3INVA 1RD7A 2DHFA 4H98A 3SR5X 3TQAA 3SRRX 4M6KA 4DPHA 4ECKA 1TDRA 3KFYA 3QLRA 3FL8A 3SQYX 3GI2A 3KY8A 4H95A 1RX9A 4NX6A 3TD8A 3QLYA 4QLEA 1HFQA 1DRFA 1DRHA 5HT5A 3NZAX 2FZIA 3FL9A 3EEKA 3NXVA 1RC4A 1S3WA 1DG5A 2HM9A 1LY4A 3JWKA 4LAEX 2P4GA 4ELHA 2HXVA 1DR6A 3CD2A 1DREA 4KD7A 1KMVA 3KJRA 3SA2A 3M09A 1LUDA 2LF1A 3NXYA 1J3IA 3NXTA 1S3VA 5HVBA 3UM8A 3E0BA 4KY4A 4EIZA 4OR7A 2G6VA 4XT6A 3QLSA 3IA5A 4KM0A 1DYHA 1LY3A 2DRCA 1AI9A 3F0XX 4PSSA 4KEBA 3SA1A 3FRDX 4KJKA 1CZ3A 1AO8A 1DR4A 3SH2A 3NXXA 4X5FA 1J3JA 4ELGA 4M6JA 1RA2A 4KLXA 3FQCA 2W3WA 1AOEA 4FHBA 1RB3A 4XT5A 5JA3A 1RB2A 4QJCA 3N0HA 4P68A 2L28A 1CD2A 3SRQX 1RA3A 3F0UX 1PD8A 2ANQA 1RX7A 3S3VA 2W3AA 3QL3A 3KJSA 3SRWX 1DDRA 4FGHA 3CL9A 3F8YA 4KJJA 2CIGA 2KGKA 3RO9A 5ECCA 3TQBA 1J3KA 1DYIA 1KMSA 1DR3A 5HSUA 1VJ3A 5E8QA 1RE7A 1DG7A 3GYFA 1JOMA 2D5NA 3FRAX 4KY8A 3K45A 2ANOA 3JTWA 1KLKA 3GHWA 4KFJA 3FY9X 5HQZA 3NZ9X 4XE6X 3EELA 1M78A 5HSRA 1U71A 2ZZAA 3LG4A 3CSEA 4KAKA 1S3YA 3FY8X 4ELFA 4X5HA 3M08A 3HBBA 3QGTA 4IXFX 2HQPA 1PD9A 3GHVA 1ZDRA 2BL9A 4DPDA 2OBCA 3JWCA 4LAHX 1S3UA 4G8ZX 2CD2A 4KNEA 1DHJA 3GHCA 2B3ZA 5HT4A 4G95A 3QYLA 3IA4A 4LEKX 1DRBA 2XW7A 3UM6A 1VDRA 1IA2A 4G3MA 2INQA 4H96A 4H97A 3OCHA 3QL0A 4QHVA 1DLSA 1BOZA 2W9HA 4RGCA 4QJZD 2W9GA 2W9TA 1RH3A 1QZFA 1DDSA 2FZJA 4HOEA 3NXRA 3CLBA 2W3MA 4X5IA 2QK8A 4XT8A 1RF7A 4ELBA 3K74A 3DRCA 1U72A 1DHIA 1M7AA 3FQOA 4PTJA 3KGYA 1HFRA 3FREX 3FYWX 4P3RA 3R33A 1M79A 2BLCA 5FDAA 4XT7A 4OSGA 3JW3A 3S9UA 1RA1A 3L3RA 3NZDA 3ROAA 3NZ6X 1RA8A 4IXED 1E26A 3DGAA 3NZBX 3F0BX 2BLAA 3SRSX 3IROA 3TQ9A 3FRBX 1DIUA 2BLBA 4TU5X 1IA3A 4M7VA 1DISA 3EX8A 4HOFA 4EIGA 4KL9A 4M7UA 4GH8A 3JW5A 3QLZA 5U27A 3NZCX 5HQYA 4QI9A 3NU0A 4P66A 2OIPA 1MVTA 5HUIA 4NX7A 4FGGA 2H2QA 2FZHA 3JSUA 1RX4A 1RX8A 1U70A 1D1GA 1RX1A 4DDRA 4ELEA 5HPBA 3DAUA 4M2XA 6DFRA 1DRAA 5HF2X 3F0QX 3FS6A 3FQ0A 4Q0DA 2JYBA 3F0SX 3Q1HA 5EAJA 4CD2A 1RX5A 1IA1A 3D84X 1SEJA 3QLXA 3NRRA 5DFRA 3DL6A 4XECX 3IRMA 3K47A 4HA7A 4I13A 5DXVA 4PTHA 4XRBA 4QLFA 4KYAA 4KJLA 3DFRA 3UM5A 5HVEA 5CCCA 3OAFA 2GD9A 3F8ZA 4I1NA 1DHFA 1RG7A 2ITHA 1RA9A 2W3VA 8DFRA 5JG0X 1PDBA 4PDJA 3TQ8A 1OHKA 3EEMA 4Q0EA 4KBNA 4EJ1A 3K2HA 1DR5A 3NTZA 3FYVX 3VCOA 1HFPA 4PSYA 3ZPCA 3IX9A 3F0VX 7DFRA 3QLWA 3DG8A 4X5JA 1JUVA 3QYOA 3ZPGA 1DG8A 2W9SA 4HA9A 1DLRA 3EEJA 4PSTA 3S7AA 3DL5A 3D80A 4Q6AA 3FQVA 5HF0X 3NXOA 1DR2A 3HJ3A 3I3RA 2W3BA 3F91A 2AZNA 4KM2A 3DATA 3FQFA 3JVXA 4LAGX 1DR7A 3IRNA 4Q67A 5ECXA 1RX2A 3QG2A 4X5GA 4P3QA 4M6LA 3FRFX 3JWFA 5U26A 5CC9A 3SRUX 1DF7A 1MVSA 3EIGA 3RG9A 5HI6A 3QFXA 1IA4A 2D0KA 1RX3A 4DFRA 1DYJA 2O7PA 3I8AX 4XT4A 2C2TA 3FQZA 1YHOA 4IXGX 2C2SA 3SGYA 1OHJA 4DP3A 1JOLA 4QLGA 1DR1A 1DYRA 1BZFA 1DAJA
chains in the Genus database with same CATH topology
1RX6A 4EILA 3SAIA 3JWMA 4HOGA 3INVA 1RD7A 2DHFA 4H98A 3SR5X 3TQAA 3SRRX 4M6KA 4DPHA 4ECKA 1TDRA 3KFYA 3QLRA 3FL8A 3SQYX 3GI2A 3KY8A 4H95A 1RX9A 4NX6A 3TD8A 3QLYA 4QLEA 1HFQA 1DRFA 1DRHA 5HT5A 3NZAX 2FZIA 3FL9A 3EEKA 3NXVA 1RC4A 1S3WA 1DG5A 2HM9A 1LY4A 3JWKA 4LAEX 2P4GA 4ELHA 2HXVA 1DR6A 3CD2A 1DREA 4KD7A 1KMVA 3KJRA 3SA2A 3M09A 1LUDA 2LF1A 3NXYA 1J3IA 3NXTA 1S3VA 5HVBA 3UM8A 3E0BA 4KY4A 4EIZA 4OR7A 2G6VA 4XT6A 3QLSA 3IA5A 4KM0A 1DYHA 1LY3A 2DRCA 1AI9A 3F0XX 4PSSA 4KEBA 3SA1A 3FRDX 4KJKA 1CZ3A 1AO8A 1DR4A 3SH2A 3NXXA 4X5FA 1J3JA 4ELGA 4M6JA 1RA2A 4KLXA 3FQCA 2W3WA 1AOEA 4FHBA 1RB3A 4XT5A 5JA3A 1RB2A 4QJCA 3N0HA 4P68A 2L28A 1CD2A 3SRQX 1RA3A 3F0UX 1PD8A 2ANQA 1RX7A 3S3VA 2W3AA 3QL3A 3KJSA 3SRWX 1DDRA 4FGHA 3CL9A 3F8YA 4KJJA 2CIGA 2KGKA 3RO9A 5ECCA 3TQBA 1J3KA 1DYIA 1KMSA 1DR3A 5HSUA 1VJ3A 5E8QA 1RE7A 1DG7A 3GYFA 1JOMA 2D5NA 3FRAX 4KY8A 3K45A 2ANOA 3JTWA 1KLKA 3GHWA 4KFJA 3FY9X 5HQZA 3NZ9X 4XE6X 3EELA 1M78A 5HSRA 1U71A 2ZZAA 3LG4A 3CSEA 4KAKA 1S3YA 3FY8X 4ELFA 4X5HA 3M08A 3HBBA 3QGTA 4IXFX 2HQPA 1PD9A 3GHVA 1ZDRA 2BL9A 4DPDA 2OBCA 3JWCA 4LAHX 1S3UA 4G8ZX 2CD2A 4KNEA 1DHJA 3GHCA 2B3ZA 5HT4A 4G95A 3QYLA 3IA4A 4LEKX 1DRBA 2XW7A 3UM6A 1VDRA 1IA2A 4G3MA 2INQA 4H96A 4H97A 3OCHA 3QL0A 4QHVA 1DLSA 1BOZA 2W9HA 4RGCA 4QJZD 2W9GA 2W9TA 1RH3A 1QZFA 1DDSA 2FZJA 4HOEA 3NXRA 3CLBA 2W3MA 4X5IA 2QK8A 4XT8A 1RF7A 4ELBA 3K74A 3DRCA 1U72A 1DHIA 1M7AA 3FQOA 4PTJA 3KGYA 1HFRA 3FREX 3FYWX 4P3RA 3R33A 1M79A 2BLCA 5FDAA 4XT7A 4OSGA 3JW3A 3S9UA 1RA1A 3L3RA 3NZDA 3ROAA 3NZ6X 1RA8A 4IXED 1E26A 3DGAA 3NZBX 3F0BX 2BLAA 3SRSX 3IROA 3TQ9A 3FRBX 1DIUA 2BLBA 4TU5X 1IA3A 4M7VA 1DISA 3EX8A 4HOFA 4EIGA 4KL9A 4M7UA 4GH8A 3JW5A 3QLZA 5U27A 3NZCX 5HQYA 4QI9A 3NU0A 4P66A 2OIPA 1MVTA 5HUIA 4NX7A 4FGGA 2H2QA 2FZHA 3JSUA 1RX4A 1RX8A 1U70A 1D1GA 1RX1A 4DDRA 4ELEA 5HPBA 3DAUA 4M2XA 6DFRA 1DRAA 5HF2X 3F0QX 3FS6A 3FQ0A 4Q0DA 2JYBA 3F0SX 3Q1HA 5EAJA 4CD2A 1RX5A 1IA1A 3D84X 1SEJA 3QLXA 3NRRA 5DFRA 3DL6A 4XECX 3IRMA 3K47A 4HA7A 4I13A 5DXVA 4PTHA 4XRBA 4QLFA 4KYAA 4KJLA 3DFRA 3UM5A 5HVEA 5CCCA 3OAFA 2GD9A 3F8ZA 4I1NA 1DHFA 1RG7A 2ITHA 1RA9A 2W3VA 8DFRA 5JG0X 1PDBA 4PDJA 3TQ8A 1OHKA 3EEMA 4Q0EA 4KBNA 4EJ1A 3K2HA 1DR5A 3NTZA 3FYVX 3VCOA 1HFPA 4PSYA 3ZPCA 3IX9A 3F0VX 7DFRA 3QLWA 3DG8A 4X5JA 1JUVA 3QYOA 3ZPGA 1DG8A 2W9SA 4HA9A 1DLRA 3EEJA 4PSTA 3S7AA 3DL5A 3D80A 4Q6AA 3FQVA 5HF0X 3NXOA 1DR2A 3HJ3A 3I3RA 2W3BA 3F91A 2AZNA 4KM2A 3DATA 3FQFA 3JVXA 4LAGX 1DR7A 3IRNA 4Q67A 5ECXA 1RX2A 3QG2A 4X5GA 4P3QA 4M6LA 3FRFX 3JWFA 5U26A 5CC9A 3SRUX 1DF7A 1MVSA 3EIGA 3RG9A 5HI6A 3QFXA 1IA4A 2D0KA 1RX3A 4DFRA 1DYJA 2O7PA 3I8AX 4XT4A 2C2TA 3FQZA 1YHOA 4IXGX 2C2SA 3SGYA 1OHJA 4DP3A 1JOLA 4QLGA 1DR1A 1DYRA 1BZFA 1DAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RX6 A;  4EIL A;  3SAI A;  3JWM A;  4HOG A;  3INV A;  1RD7 A;  2DHF A;  4H98 A;  3SR5 X;  3TQA A;  3SRR X;  4M6K A;  4DPH A;  4ECK A;  1TDR A;  3KFY A;  3QLR A;  3FL8 A;  3SQY X;  3GI2 A;  3KY8 A;  4H95 A;  1RX9 A;  4NX6 A;  3TD8 A;  3QLY A;  4QLE A;  1HFQ A;  1DRF A;  1DRH A;  5HT5 A;  3NZA X;  2FZI A;  3FL9 A;  3EEK A;  3NXV A;  1RC4 A;  1S3W A;  1DG5 A;  2HM9 A;  1LY4 A;  3JWK A;  4LAE X;  2P4G A;  4ELH A;  2HXV A;  1DR6 A;  3CD2 A;  1DRE A;  4KD7 A;  1KMV A;  3KJR A;  3SA2 A;  3M09 A;  1LUD A;  2LF1 A;  3NXY A;  1J3I A;  3NXT A;  1S3V A;  5HVB A;  3UM8 A;  3E0B A;  4KY4 A;  4EIZ A;  4OR7 A;  2G6V A;  4XT6 A;  3QLS A;  3IA5 A;  4KM0 A;  1DYH A;  1LY3 A;  2DRC A;  1AI9 A;  3F0X X;  4PSS A;  4KEB A;  3SA1 A;  3FRD X;  4KJK A;  1CZ3 A;  1AO8 A;  1DR4 A;  3SH2 A;  3NXX A;  4X5F A;  1J3J A;  4ELG A;  4M6J A;  1RA2 A;  4KLX A;  3FQC A;  2W3W A;  1AOE A;  4FHB A;  1RB3 A;  4XT5 A;  5JA3 A;  1RB2 A;  4QJC A;  3N0H A;  4P68 A;  2L28 A;  1CD2 A;  3SRQ X;  1RA3 A;  3F0U X;  1PD8 A;  2ANQ A;  1RX7 A;  3S3V A;  2W3A A;  3QL3 A;  3KJS A;  3SRW X;  1DDR A;  4FGH A;  3CL9 A;  3F8Y A;  4KJJ A;  2CIG A;  2KGK A;  3RO9 A;  5ECC A;  3TQB A;  1J3K A;  1DYI A;  1KMS A;  1DR3 A;  5HSU A;  1VJ3 A;  5E8Q A;  1RE7 A;  1DG7 A;  3GYF A;  1JOM A;  2D5N A;  3FRA X;  4KY8 A;  3K45 A;  2ANO A;  3JTW A;  1KLK A;  3GHW A;  4KFJ A;  3FY9 X;  5HQZ A;  3NZ9 X;  4XE6 X;  3EEL A;  1M78 A;  5HSR A;  1U71 A;  2ZZA A;  3LG4 A;  3CSE A;  4KAK A;  1S3Y A;  3FY8 X;  4ELF A;  4X5H A;  3M08 A;  3HBB A;  3QGT A;  4IXF X;  2HQP A;  1PD9 A;  3GHV A;  1ZDR A;  2BL9 A;  4DPD A;  2OBC A;  3JWC A;  4LAH X;  1S3U A;  4G8Z X;  2CD2 A;  4KNE A;  1DHJ A;  3GHC A;  2B3Z A;  5HT4 A;  4G95 A;  3QYL A;  3IA4 A;  4LEK X;  1DRB A;  2XW7 A;  3UM6 A;  1VDR A;  1IA2 A;  4G3M A;  2INQ A;  4H96 A;  4H97 A;  3OCH A;  3QL0 A;  4QHV A;  1DLS A;  1BOZ A;  2W9H A;  4RGC A;  4QJZ D;  2W9G A;  2W9T A;  1RH3 A;  1QZF A;  1DDS A;  2FZJ A;  4HOE A;  3NXR A;  3CLB A;  2W3M A;  4X5I A;  2QK8 A;  4XT8 A;  1RF7 A;  4ELB A;  3K74 A;  3DRC A;  1U72 A;  1DHI A;  1M7A A;  3FQO A;  4PTJ A;  3KGY A;  1HFR A;  3FRE X;  3FYW X;  4P3R A;  3R33 A;  1M79 A;  2BLC A;  5FDA A;  4XT7 A;  4OSG A;  3JW3 A;  3S9U A;  1RA1 A;  3L3R A;  3NZD A;  3ROA A;  3NZ6 X;  1RA8 A;  4IXE D;  1E26 A;  3DGA A;  3NZB X;  3F0B X;  2BLA A;  3SRS X;  3IRO A;  3TQ9 A;  3FRB X;  1DIU A;  2BLB A;  4TU5 X;  1IA3 A;  4M7V A;  1DIS A;  3EX8 A;  4HOF A;  4EIG A;  4KL9 A;  4M7U A;  4GH8 A;  3JW5 A;  3QLZ A;  5U27 A;  3NZC X;  5HQY A;  4QI9 A;  3NU0 A;  4P66 A;  2OIP A;  1MVT A;  5HUI A;  4NX7 A;  4FGG A;  2H2Q A;  2FZH A;  3JSU A;  1RX4 A;  1RX8 A;  1U70 A;  1D1G A;  1RX1 A;  4DDR A;  4ELE A;  5HPB A;  3DAU A;  4M2X A;  6DFR A;  1DRA A;  5HF2 X;  3F0Q X;  3FS6 A;  3FQ0 A;  4Q0D A;  2JYB A;  3F0S X;  3Q1H A;  5EAJ A;  4CD2 A;  1RX5 A;  1IA1 A;  3D84 X;  1SEJ A;  3QLX A;  3NRR A;  5DFR A;  3DL6 A;  4XEC X;  3IRM A;  3K47 A;  4HA7 A;  4I13 A;  5DXV A;  4PTH A;  4XRB A;  4QLF A;  4KYA A;  4KJL A;  3DFR A;  3UM5 A;  5HVE A;  5CCC A;  3OAF A;  2GD9 A;  3F8Z A;  4I1N A;  1DHF A;  1RG7 A;  2ITH A;  1RA9 A;  2W3V A;  8DFR A;  5JG0 X;  1PDB A;  4PDJ A;  3TQ8 A;  1OHK A;  3EEM A;  4Q0E A;  4KBN A;  4EJ1 A;  3K2H A;  1DR5 A;  3NTZ A;  3FYV X;  3VCO A;  1HFP A;  4PSY A;  3ZPC A;  3IX9 A;  3F0V X;  7DFR A;  3QLW A;  3DG8 A;  4X5J A;  1JUV A;  3QYO A;  3ZPG A;  1DG8 A;  2W9S A;  4HA9 A;  1DLR A;  3EEJ A;  4PST A;  3S7A A;  3DL5 A;  3D80 A;  4Q6A A;  3FQV A;  5HF0 X;  3NXO A;  1DR2 A;  3HJ3 A;  3I3R A;  2W3B A;  3F91 A;  2AZN A;  4KM2 A;  3DAT A;  3FQF A;  3JVX A;  4LAG X;  1DR7 A;  3IRN A;  4Q67 A;  5ECX A;  1RX2 A;  3QG2 A;  4X5G A;  4P3Q A;  4M6L A;  3FRF X;  3JWF A;  5U26 A;  5CC9 A;  3SRU X;  1DF7 A;  1MVS A;  3EIG A;  3RG9 A;  5HI6 A;  3QFX A;  1IA4 A;  2D0K A;  1RX3 A;  4DFR A;  1DYJ A;  2O7P A;  3I8A X;  4XT4 A;  2C2T A;  3FQZ A;  1YHO A;  4IXG X;  2C2S A;  3SGY A;  1OHJ A;  4DP3 A;  1JOL A;  4QLG A;  1DR1 A;  1DYR A;  1BZF A;  1DAJ A; 
#chains in the Genus database with same CATH topology
 1RX6 A;  4EIL A;  3SAI A;  3JWM A;  4HOG A;  3INV A;  1RD7 A;  2DHF A;  4H98 A;  3SR5 X;  3TQA A;  3SRR X;  4M6K A;  4DPH A;  4ECK A;  1TDR A;  3KFY A;  3QLR A;  3FL8 A;  3SQY X;  3GI2 A;  3KY8 A;  4H95 A;  1RX9 A;  4NX6 A;  3TD8 A;  3QLY A;  4QLE A;  1HFQ A;  1DRF A;  1DRH A;  5HT5 A;  3NZA X;  2FZI A;  3FL9 A;  3EEK A;  3NXV A;  1RC4 A;  1S3W A;  1DG5 A;  2HM9 A;  1LY4 A;  3JWK A;  4LAE X;  2P4G A;  4ELH A;  2HXV A;  1DR6 A;  3CD2 A;  1DRE A;  4KD7 A;  1KMV A;  3KJR A;  3SA2 A;  3M09 A;  1LUD A;  2LF1 A;  3NXY A;  1J3I A;  3NXT A;  1S3V A;  5HVB A;  3UM8 A;  3E0B A;  4KY4 A;  4EIZ A;  4OR7 A;  2G6V A;  4XT6 A;  3QLS A;  3IA5 A;  4KM0 A;  1DYH A;  1LY3 A;  2DRC A;  1AI9 A;  3F0X X;  4PSS A;  4KEB A;  3SA1 A;  3FRD X;  4KJK A;  1CZ3 A;  1AO8 A;  1DR4 A;  3SH2 A;  3NXX A;  4X5F A;  1J3J A;  4ELG A;  4M6J A;  1RA2 A;  4KLX A;  3FQC A;  2W3W A;  1AOE A;  4FHB A;  1RB3 A;  4XT5 A;  5JA3 A;  1RB2 A;  4QJC A;  3N0H A;  4P68 A;  2L28 A;  1CD2 A;  3SRQ X;  1RA3 A;  3F0U X;  1PD8 A;  2ANQ A;  1RX7 A;  3S3V A;  2W3A A;  3QL3 A;  3KJS A;  3SRW X;  1DDR A;  4FGH A;  3CL9 A;  3F8Y A;  4KJJ A;  2CIG A;  2KGK A;  3RO9 A;  5ECC A;  3TQB A;  1J3K A;  1DYI A;  1KMS A;  1DR3 A;  5HSU A;  1VJ3 A;  5E8Q A;  1RE7 A;  1DG7 A;  3GYF A;  1JOM A;  2D5N A;  3FRA X;  4KY8 A;  3K45 A;  2ANO A;  3JTW A;  1KLK A;  3GHW A;  4KFJ A;  3FY9 X;  5HQZ A;  3NZ9 X;  4XE6 X;  3EEL A;  1M78 A;  5HSR A;  1U71 A;  2ZZA A;  3LG4 A;  3CSE A;  4KAK A;  1S3Y A;  3FY8 X;  4ELF A;  4X5H A;  3M08 A;  3HBB A;  3QGT A;  4IXF X;  2HQP A;  1PD9 A;  3GHV A;  1ZDR A;  2BL9 A;  4DPD A;  2OBC A;  3JWC A;  4LAH X;  1S3U A;  4G8Z X;  2CD2 A;  4KNE A;  1DHJ A;  3GHC A;  2B3Z A;  5HT4 A;  4G95 A;  3QYL A;  3IA4 A;  4LEK X;  1DRB A;  2XW7 A;  3UM6 A;  1VDR A;  1IA2 A;  4G3M A;  2INQ A;  4H96 A;  4H97 A;  3OCH A;  3QL0 A;  4QHV A;  1DLS A;  1BOZ A;  2W9H A;  4RGC A;  4QJZ D;  2W9G A;  2W9T A;  1RH3 A;  1QZF A;  1DDS A;  2FZJ A;  4HOE A;  3NXR A;  3CLB A;  2W3M A;  4X5I A;  2QK8 A;  4XT8 A;  1RF7 A;  4ELB A;  3K74 A;  3DRC A;  1U72 A;  1DHI A;  1M7A A;  3FQO A;  4PTJ A;  3KGY A;  1HFR A;  3FRE X;  3FYW X;  4P3R A;  3R33 A;  1M79 A;  2BLC A;  5FDA A;  4XT7 A;  4OSG A;  3JW3 A;  3S9U A;  1RA1 A;  3L3R A;  3NZD A;  3ROA A;  3NZ6 X;  1RA8 A;  4IXE D;  1E26 A;  3DGA A;  3NZB X;  3F0B X;  2BLA A;  3SRS X;  3IRO A;  3TQ9 A;  3FRB X;  1DIU A;  2BLB A;  4TU5 X;  1IA3 A;  4M7V A;  1DIS A;  3EX8 A;  4HOF A;  4EIG A;  4KL9 A;  4M7U A;  4GH8 A;  3JW5 A;  3QLZ A;  5U27 A;  3NZC X;  5HQY A;  4QI9 A;  3NU0 A;  4P66 A;  2OIP A;  1MVT A;  5HUI A;  4NX7 A;  4FGG A;  2H2Q A;  2FZH A;  3JSU A;  1RX4 A;  1RX8 A;  1U70 A;  1D1G A;  1RX1 A;  4DDR A;  4ELE A;  5HPB A;  3DAU A;  4M2X A;  6DFR A;  1DRA A;  5HF2 X;  3F0Q X;  3FS6 A;  3FQ0 A;  4Q0D A;  2JYB A;  3F0S X;  3Q1H A;  5EAJ A;  4CD2 A;  1RX5 A;  1IA1 A;  3D84 X;  1SEJ A;  3QLX A;  3NRR A;  5DFR A;  3DL6 A;  4XEC X;  3IRM A;  3K47 A;  4HA7 A;  4I13 A;  5DXV A;  4PTH A;  4XRB A;  4QLF A;  4KYA A;  4KJL A;  3DFR A;  3UM5 A;  5HVE A;  5CCC A;  3OAF A;  2GD9 A;  3F8Z A;  4I1N A;  1DHF A;  1RG7 A;  2ITH A;  1RA9 A;  2W3V A;  8DFR A;  5JG0 X;  1PDB A;  4PDJ A;  3TQ8 A;  1OHK A;  3EEM A;  4Q0E A;  4KBN A;  4EJ1 A;  3K2H A;  1DR5 A;  3NTZ A;  3FYV X;  3VCO A;  1HFP A;  4PSY A;  3ZPC A;  3IX9 A;  3F0V X;  7DFR A;  3QLW A;  3DG8 A;  4X5J A;  1JUV A;  3QYO A;  3ZPG A;  1DG8 A;  2W9S A;  4HA9 A;  1DLR A;  3EEJ A;  4PST A;  3S7A A;  3DL5 A;  3D80 A;  4Q6A A;  3FQV A;  5HF0 X;  3NXO A;  1DR2 A;  3HJ3 A;  3I3R A;  2W3B A;  3F91 A;  2AZN A;  4KM2 A;  3DAT A;  3FQF A;  3JVX A;  4LAG X;  1DR7 A;  3IRN A;  4Q67 A;  5ECX A;  1RX2 A;  3QG2 A;  4X5G A;  4P3Q A;  4M6L A;  3FRF X;  3JWF A;  5U26 A;  5CC9 A;  3SRU X;  1DF7 A;  1MVS A;  3EIG A;  3RG9 A;  5HI6 A;  3QFX A;  1IA4 A;  2D0K A;  1RX3 A;  4DFR A;  1DYJ A;  2O7P A;  3I8A X;  4XT4 A;  2C2T A;  3FQZ A;  1YHO A;  4IXG X;  2C2S A;  3SGY A;  1OHJ A;  4DP3 A;  1JOL A;  4QLG A;  1DR1 A;  1DYR A;  1BZF A;  1DAJ A; 
#chains in the Genus database with same CATH homology
 1RX6 A;  4EIL A;  3SAI A;  3JWM A;  4HOG A;  3INV A;  1RD7 A;  2DHF A;  4H98 A;  3SR5 X;  3TQA A;  3SRR X;  4M6K A;  4DPH A;  4ECK A;  1TDR A;  3KFY A;  3QLR A;  3FL8 A;  3SQY X;  3GI2 A;  3KY8 A;  4H95 A;  1RX9 A;  4NX6 A;  3TD8 A;  3QLY A;  4QLE A;  1HFQ A;  1DRF A;  1DRH A;  5HT5 A;  3NZA X;  2FZI A;  3FL9 A;  3EEK A;  3NXV A;  1RC4 A;  1S3W A;  1DG5 A;  2HM9 A;  1LY4 A;  3JWK A;  4LAE X;  2P4G A;  4ELH A;  2HXV A;  1DR6 A;  3CD2 A;  1DRE A;  4KD7 A;  1KMV A;  3KJR A;  3SA2 A;  3M09 A;  1LUD A;  2LF1 A;  3NXY A;  1J3I A;  3NXT A;  1S3V A;  5HVB A;  3UM8 A;  3E0B A;  4KY4 A;  4EIZ A;  4OR7 A;  2G6V A;  4XT6 A;  3QLS A;  3IA5 A;  4KM0 A;  1DYH A;  1LY3 A;  2DRC A;  1AI9 A;  3F0X X;  4PSS A;  4KEB A;  3SA1 A;  3FRD X;  4KJK A;  1CZ3 A;  1AO8 A;  1DR4 A;  3SH2 A;  3NXX A;  4X5F A;  1J3J A;  4ELG A;  4M6J A;  1RA2 A;  4KLX A;  3FQC A;  2W3W A;  1AOE A;  4FHB A;  1RB3 A;  4XT5 A;  5JA3 A;  1RB2 A;  4QJC A;  3N0H A;  4P68 A;  2L28 A;  1CD2 A;  3SRQ X;  1RA3 A;  3F0U X;  1PD8 A;  2ANQ A;  1RX7 A;  3S3V A;  2W3A A;  3QL3 A;  3KJS A;  3SRW X;  1DDR A;  4FGH A;  3CL9 A;  3F8Y A;  4KJJ A;  2CIG A;  2KGK A;  3RO9 A;  5ECC A;  3TQB A;  1J3K A;  1DYI A;  1KMS A;  1DR3 A;  5HSU A;  1VJ3 A;  5E8Q A;  1RE7 A;  1DG7 A;  3GYF A;  1JOM A;  2D5N A;  3FRA X;  4KY8 A;  3K45 A;  2ANO A;  3JTW A;  1KLK A;  3GHW A;  4KFJ A;  3FY9 X;  5HQZ A;  3NZ9 X;  4XE6 X;  3EEL A;  1M78 A;  5HSR A;  1U71 A;  2ZZA A;  3LG4 A;  3CSE A;  4KAK A;  1S3Y A;  3FY8 X;  4ELF A;  4X5H A;  3M08 A;  3HBB A;  3QGT A;  4IXF X;  2HQP A;  1PD9 A;  3GHV A;  1ZDR A;  2BL9 A;  4DPD A;  2OBC A;  3JWC A;  4LAH X;  1S3U A;  4G8Z X;  2CD2 A;  4KNE A;  1DHJ A;  3GHC A;  2B3Z A;  5HT4 A;  4G95 A;  3QYL A;  3IA4 A;  4LEK X;  1DRB A;  2XW7 A;  3UM6 A;  1VDR A;  1IA2 A;  4G3M A;  2INQ A;  4H96 A;  4H97 A;  3OCH A;  3QL0 A;  4QHV A;  1DLS A;  1BOZ A;  2W9H A;  4RGC A;  4QJZ D;  2W9G A;  2W9T A;  1RH3 A;  1QZF A;  1DDS A;  2FZJ A;  4HOE A;  3NXR A;  3CLB A;  2W3M A;  4X5I A;  2QK8 A;  4XT8 A;  1RF7 A;  4ELB A;  3K74 A;  3DRC A;  1U72 A;  1DHI A;  1M7A A;  3FQO A;  4PTJ A;  3KGY A;  1HFR A;  3FRE X;  3FYW X;  4P3R A;  3R33 A;  1M79 A;  2BLC A;  5FDA A;  4XT7 A;  4OSG A;  3JW3 A;  3S9U A;  1RA1 A;  3L3R A;  3NZD A;  3ROA A;  3NZ6 X;  1RA8 A;  4IXE D;  1E26 A;  3DGA A;  3NZB X;  3F0B X;  2BLA A;  3SRS X;  3IRO A;  3TQ9 A;  3FRB X;  1DIU A;  2BLB A;  4TU5 X;  1IA3 A;  4M7V A;  1DIS A;  3EX8 A;  4HOF A;  4EIG A;  4KL9 A;  4M7U A;  4GH8 A;  3JW5 A;  3QLZ A;  5U27 A;  3NZC X;  5HQY A;  4QI9 A;  3NU0 A;  4P66 A;  2OIP A;  1MVT A;  5HUI A;  4NX7 A;  4FGG A;  2H2Q A;  2FZH A;  3JSU A;  1RX4 A;  1RX8 A;  1U70 A;  1D1G A;  1RX1 A;  4DDR A;  4ELE A;  5HPB A;  3DAU A;  4M2X A;  6DFR A;  1DRA A;  5HF2 X;  3F0Q X;  3FS6 A;  3FQ0 A;  4Q0D A;  2JYB A;  3F0S X;  3Q1H A;  5EAJ A;  4CD2 A;  1RX5 A;  1IA1 A;  3D84 X;  1SEJ A;  3QLX A;  3NRR A;  5DFR A;  3DL6 A;  4XEC X;  3IRM A;  3K47 A;  4HA7 A;  4I13 A;  5DXV A;  4PTH A;  4XRB A;  4QLF A;  4KYA A;  4KJL A;  3DFR A;  3UM5 A;  5HVE A;  5CCC A;  3OAF A;  2GD9 A;  3F8Z A;  4I1N A;  1DHF A;  1RG7 A;  2ITH A;  1RA9 A;  2W3V A;  8DFR A;  5JG0 X;  1PDB A;  4PDJ A;  3TQ8 A;  1OHK A;  3EEM A;  4Q0E A;  4KBN A;  4EJ1 A;  3K2H A;  1DR5 A;  3NTZ A;  3FYV X;  3VCO A;  1HFP A;  4PSY A;  3ZPC A;  3IX9 A;  3F0V X;  7DFR A;  3QLW A;  3DG8 A;  4X5J A;  1JUV A;  3QYO A;  3ZPG A;  1DG8 A;  2W9S A;  4HA9 A;  1DLR A;  3EEJ A;  4PST A;  3S7A A;  3DL5 A;  3D80 A;  4Q6A A;  3FQV A;  5HF0 X;  3NXO A;  1DR2 A;  3HJ3 A;  3I3R A;  2W3B A;  3F91 A;  2AZN A;  4KM2 A;  3DAT A;  3FQF A;  3JVX A;  4LAG X;  1DR7 A;  3IRN A;  4Q67 A;  5ECX A;  1RX2 A;  3QG2 A;  4X5G A;  4P3Q A;  4M6L A;  3FRF X;  3JWF A;  5U26 A;  5CC9 A;  3SRU X;  1DF7 A;  1MVS A;  3EIG A;  3RG9 A;  5HI6 A;  3QFX A;  1IA4 A;  2D0K A;  1RX3 A;  4DFR A;  1DYJ A;  2O7P A;  3I8A X;  4XT4 A;  2C2T A;  3FQZ A;  1YHO A;  4IXG X;  2C2S A;  3SGY A;  1OHJ A;  4DP3 A;  1JOL A;  4QLG A;  1DR1 A;  1DYR A;  1BZF A;  1DAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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