3FQVA

Staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 39
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fqvA00
2HXVA 3CLBA 3F8ZA 1IA2A 1HFQA 1LY4A 4KYAA 3QL3A 3QGTA 1PDBA 1DG5A 3FQOA 3CL9A 1DDSA 1RH3A 3FYWX 2DRCA 2OIPA 3SGYA 4H95A 4KD7A 2W3MA 1DIUA 1BOZA 3SR5X 4HOGA 1DR2A 1DRHA 3QG2A 3UM8A 2ITHA 5E8QA 1DRFA 3JVXA 1AO8A 3KFYA 1JUVA 2W3VA 1OHJA 3FQZA 4NX7A 3F0UX 3TQAA 3EIGA 5HPBA 1BZFA 1AOEA 4LEKX 4KY4A 3FY9X 4X5IA 1RA8A 2INQA 4Q0DA 3LG4A 2B3ZA 4XT7A 1RX3A 4KNEA 3NXRA 3S3VA 3DL6A 1TDRA 1JOMA 4G3MA 4M6KA 4XE6X 3SRQX 3R33A 1DHFA 3INVA 2FZJA 2P4GA 1HFRA 4IXGX 4EIGA 1RX4A 2G6VA 5U26A 1RX5A 2HM9A 3GHWA 1S3UA 1RC4A 1DLRA 2W3WA 3ROAA 3UM6A 3JWKA 3F8YA 1IA3A 3JWCA 1KLKA 2ANQA 3EEMA 3OAFA 1RA3A 3NZCX 1DR6A 3GI2A 1DYJA 3EEJA 3IA4A 4FHBA 2L28A 1CD2A 1RB3A 4X5FA 5HQYA 2W9HA 3FL8A 4Q6AA 1DDRA 2W3BA 3FY8X 1RX8A 2GD9A 4QJCA 3TQ8A 4IXED 3F0QX 2CD2A 1AI9A 3I8AX 4KFJA 5HQZA 3SRWX 1RA2A 3NZBX 1MVTA 1IA1A 3QFXA 4LAGX 3F91A 3SRRX 3N0HA 4PTJA 1QZFA 3FRDX 3NXXA 3QLSA 4XT5A 4KY8A 3JW3A 3SQYX 1SEJA 4XT4A 4M7UA 3JW5A 1RA1A 2BLBA 3NXTA 1IA4A 4H98A 1DHJA 3QLZA 5DFRA 2W3AA 3CD2A 4KJKA 2H2QA 3QYOA 1DAJA 4HA9A 3GYFA 3GHVA 2FZHA 1RF7A 5HUIA 3QLYA 3SH2A 4DPHA 1RD7A 3K47A 3NXOA 1VJ3A 4XECX 4DDRA 3D84X 3FRAX 1DLSA 2JYBA 1DR3A 3K45A 2AZNA 1M78A 4P3QA 4Q67A 3JWMA 3K2HA 4KJJA 3EEKA 4HA7A 4KAKA 4I13A 1VDRA 4EILA 3FRBX 5HI6A 1RX6A 4PSTA 1CZ3A 4QLFA 4H97A 4H96A 3M09A 4KL9A 1DR1A 4XT8A 1DISA 3F0XX 1RA9A 3SA2A 3E0BA 3NRRA 3S9UA 3DRCA 4Q0EA 4P68A 3F0BX 4KBNA 2W9GA 3F0VX 4P3RA 4ELEA 1LY3A 4NX6A 1J3IA 3FL9A 3FQCA 1DF7A 5HF2X 1DRBA 1OHKA 3FQ0A 3DL5A 5HT5A 3NU0A 3DAUA 4M6LA 3GHCA 4I1NA 1U71A 4PSSA 5FDAA 3NZ6X 4ECKA 2ANOA 4XT6A 3IX9A 4EIZA 1LUDA 8DFRA 5HF0X 4TU5X 1KMVA 3FQVA 3QLXA 2OBCA 1JOLA 3DATA 4RGCA 1ZDRA 1DHIA 1RX1A 4QI9A 4KLXA 3QLWA 5CC9A 3QL0A 4IXFX 3NZAX 3TD8A 4DPDA 2XW7A 4QHVA 4GH8A 4KM2A 3SAIA 2D0KA 1DYIA 4HOEA 5DXVA 4PTHA 3QYLA 1PD8A 3UM5A 4DP3A 3OCHA 3FYVX 4KEBA 2C2SA 3CSEA 2QK8A 1U72A 5JA3A 3DGAA 3S7AA 4ELBA 3FRFX 2W9SA 4QLEA 2HQPA 3KGYA 2CIGA 3RG9A 4X5GA 5U27A 3EX8A 1S3YA 1DG8A 3FS6A 3IRMA 4G95A 3I3RA 3TQ9A 1MVSA 3IA5A 3M08A 4M7VA 2C2TA 1DR4A 2W9TA 4FGGA 4X5HA 6DFRA 2D5NA 2BL9A 4LAHX 3NXVA 3NTZA 4KJLA 1M7AA 5EAJA 3D80A 5HSRA 3FQFA 3F0SX 1E26A 4M2XA 5ECCA 3FREX 3HJ3A 3Q1HA 3RO9A 3HBBA 7DFRA 2KGKA 3NXYA 4P66A 4LAEX 3K74A 4EJ1A 5CCCA 3IRNA 2BLAA 3JWFA 2FZIA 4X5JA 4PSYA 3SRSX 1U70A 4OR7A 4G8ZX 1RX7A 1S3VA 1RX2A 2DHFA 3IROA 2BLCA 3ZPCA 3L3RA 4QJZD 4OSGA 3SRUX 1DR7A 4QLGA 4DFRA 3DFRA 4PDJA 1D1GA 3KJSA 4ELFA 5HT4A 3NZDA 1PD9A 1RB2A 1DYHA 3NZ9X 3VCOA 2LF1A 4ELHA 2ZZAA 1DG7A 1DRAA 4XRBA 3QLRA 5HVEA 3DG8A 2O7PA 5JG0X 1J3JA 1RG7A 1HFPA 1DYRA 1RE7A 4M6JA 1KMSA 1DR5A 4ELGA 1YHOA 3KY8A 4KM0A 1M79A 4HOFA 1RX9A 3EELA 3ZPGA 5HSUA 1DREA 5ECXA 3TQBA 5HVBA 4CD2A 4FGHA 1J3KA 3JSUA 3KJRA 3JTWA 3SA1A 1S3WA
chains in the Genus database with same CATH superfamily
2HXVA 3CLBA 3F8ZA 1IA2A 1HFQA 1LY4A 4KYAA 3QL3A 3QGTA 1PDBA 1DG5A 3FQOA 3CL9A 1DDSA 1RH3A 3FYWX 2DRCA 2OIPA 3SGYA 4H95A 4KD7A 2W3MA 1DIUA 1BOZA 3SR5X 4HOGA 1DR2A 1DRHA 3QG2A 3UM8A 2ITHA 5E8QA 1DRFA 3JVXA 1AO8A 3KFYA 1JUVA 2W3VA 1OHJA 3FQZA 4NX7A 3F0UX 3TQAA 3EIGA 5HPBA 1BZFA 1AOEA 4LEKX 4KY4A 3FY9X 4X5IA 1RA8A 2INQA 4Q0DA 3LG4A 2B3ZA 4XT7A 1RX3A 4KNEA 3NXRA 3S3VA 3DL6A 1TDRA 1JOMA 4G3MA 4M6KA 4XE6X 3SRQX 3R33A 1DHFA 3INVA 2FZJA 2P4GA 1HFRA 4IXGX 4EIGA 1RX4A 2G6VA 5U26A 1RX5A 2HM9A 3GHWA 1S3UA 1RC4A 1DLRA 2W3WA 3ROAA 3UM6A 3JWKA 3F8YA 1IA3A 3JWCA 1KLKA 2ANQA 3EEMA 3OAFA 1RA3A 3NZCX 1DR6A 3GI2A 1DYJA 3EEJA 3IA4A 4FHBA 2L28A 1CD2A 1RB3A 4X5FA 5HQYA 2W9HA 3FL8A 4Q6AA 1DDRA 2W3BA 3FY8X 1RX8A 2GD9A 4QJCA 3TQ8A 4IXED 3F0QX 2CD2A 1AI9A 3I8AX 4KFJA 5HQZA 3SRWX 1RA2A 3NZBX 1MVTA 1IA1A 3QFXA 4LAGX 3F91A 3SRRX 3N0HA 4PTJA 1QZFA 3FRDX 3NXXA 3QLSA 4XT5A 4KY8A 3JW3A 3SQYX 1SEJA 4XT4A 4M7UA 3JW5A 1RA1A 2BLBA 3NXTA 1IA4A 4H98A 1DHJA 3QLZA 5DFRA 2W3AA 3CD2A 4KJKA 2H2QA 3QYOA 1DAJA 4HA9A 3GYFA 3GHVA 2FZHA 1RF7A 5HUIA 3QLYA 3SH2A 4DPHA 1RD7A 3K47A 3NXOA 1VJ3A 4XECX 4DDRA 3D84X 3FRAX 1DLSA 2JYBA 1DR3A 3K45A 2AZNA 1M78A 4P3QA 4Q67A 3JWMA 3K2HA 4KJJA 3EEKA 4HA7A 4KAKA 4I13A 1VDRA 4EILA 3FRBX 5HI6A 1RX6A 4PSTA 1CZ3A 4QLFA 4H97A 4H96A 3M09A 4KL9A 1DR1A 4XT8A 1DISA 3F0XX 1RA9A 3SA2A 3E0BA 3NRRA 3S9UA 3DRCA 4Q0EA 4P68A 3F0BX 4KBNA 2W9GA 3F0VX 4P3RA 4ELEA 1LY3A 4NX6A 1J3IA 3FL9A 3FQCA 1DF7A 5HF2X 1DRBA 1OHKA 3FQ0A 3DL5A 5HT5A 3NU0A 3DAUA 4M6LA 3GHCA 4I1NA 1U71A 4PSSA 5FDAA 3NZ6X 4ECKA 2ANOA 4XT6A 3IX9A 4EIZA 1LUDA 8DFRA 5HF0X 4TU5X 1KMVA 3FQVA 3QLXA 2OBCA 1JOLA 3DATA 4RGCA 1ZDRA 1DHIA 1RX1A 4QI9A 4KLXA 3QLWA 5CC9A 3QL0A 4IXFX 3NZAX 3TD8A 4DPDA 2XW7A 4QHVA 4GH8A 4KM2A 3SAIA 2D0KA 1DYIA 4HOEA 5DXVA 4PTHA 3QYLA 1PD8A 3UM5A 4DP3A 3OCHA 3FYVX 4KEBA 2C2SA 3CSEA 2QK8A 1U72A 5JA3A 3DGAA 3S7AA 4ELBA 3FRFX 2W9SA 4QLEA 2HQPA 3KGYA 2CIGA 3RG9A 4X5GA 5U27A 3EX8A 1S3YA 1DG8A 3FS6A 3IRMA 4G95A 3I3RA 3TQ9A 1MVSA 3IA5A 3M08A 4M7VA 2C2TA 1DR4A 2W9TA 4FGGA 4X5HA 6DFRA 2D5NA 2BL9A 4LAHX 3NXVA 3NTZA 4KJLA 1M7AA 5EAJA 3D80A 5HSRA 3FQFA 3F0SX 1E26A 4M2XA 5ECCA 3FREX 3HJ3A 3Q1HA 3RO9A 3HBBA 7DFRA 2KGKA 3NXYA 4P66A 4LAEX 3K74A 4EJ1A 5CCCA 3IRNA 2BLAA 3JWFA 2FZIA 4X5JA 4PSYA 3SRSX 1U70A 4OR7A 4G8ZX 1RX7A 1S3VA 1RX2A 2DHFA 3IROA 2BLCA 3ZPCA 3L3RA 4QJZD 4OSGA 3SRUX 1DR7A 4QLGA 4DFRA 3DFRA 4PDJA 1D1GA 3KJSA 4ELFA 5HT4A 3NZDA 1PD9A 1RB2A 1DYHA 3NZ9X 3VCOA 2LF1A 4ELHA 2ZZAA 1DG7A 1DRAA 4XRBA 3QLRA 5HVEA 3DG8A 2O7PA 5JG0X 1J3JA 1RG7A 1HFPA 1DYRA 1RE7A 4M6JA 1KMSA 1DR5A 4ELGA 1YHOA 3KY8A 4KM0A 1M79A 4HOFA 1RX9A 3EELA 3ZPGA 5HSUA 1DREA 5ECXA 3TQBA 5HVBA 4CD2A 4FGHA 1J3KA 3JSUA 3KJRA 3JTWA 3SA1A 1S3WA
chains in the Genus database with same CATH topology
2HXVA 3CLBA 3F8ZA 1IA2A 1HFQA 1LY4A 4KYAA 3QL3A 3QGTA 1PDBA 1DG5A 3FQOA 3CL9A 1DDSA 1RH3A 3FYWX 2DRCA 2OIPA 3SGYA 4H95A 4KD7A 2W3MA 1DIUA 1BOZA 3SR5X 4HOGA 1DR2A 1DRHA 3QG2A 3UM8A 2ITHA 5E8QA 1DRFA 3JVXA 1AO8A 3KFYA 1JUVA 2W3VA 1OHJA 3FQZA 4NX7A 3F0UX 3TQAA 3EIGA 5HPBA 1BZFA 1AOEA 4LEKX 4KY4A 3FY9X 4X5IA 1RA8A 2INQA 4Q0DA 3LG4A 2B3ZA 4XT7A 1RX3A 4KNEA 3NXRA 3S3VA 3DL6A 1TDRA 1JOMA 4G3MA 4M6KA 4XE6X 3SRQX 3R33A 1DHFA 3INVA 2FZJA 2P4GA 1HFRA 4IXGX 4EIGA 1RX4A 2G6VA 5U26A 1RX5A 2HM9A 3GHWA 1S3UA 1RC4A 1DLRA 2W3WA 3ROAA 3UM6A 3JWKA 3F8YA 1IA3A 3JWCA 1KLKA 2ANQA 3EEMA 3OAFA 1RA3A 3NZCX 1DR6A 3GI2A 1DYJA 3EEJA 3IA4A 4FHBA 2L28A 1CD2A 1RB3A 4X5FA 5HQYA 2W9HA 3FL8A 4Q6AA 1DDRA 2W3BA 3FY8X 1RX8A 2GD9A 4QJCA 3TQ8A 4IXED 3F0QX 2CD2A 1AI9A 3I8AX 4KFJA 5HQZA 3SRWX 1RA2A 3NZBX 1MVTA 1IA1A 3QFXA 4LAGX 3F91A 3SRRX 3N0HA 4PTJA 1QZFA 3FRDX 3NXXA 3QLSA 4XT5A 4KY8A 3JW3A 3SQYX 1SEJA 4XT4A 4M7UA 3JW5A 1RA1A 2BLBA 3NXTA 1IA4A 4H98A 1DHJA 3QLZA 5DFRA 2W3AA 3CD2A 4KJKA 2H2QA 3QYOA 1DAJA 4HA9A 3GYFA 3GHVA 2FZHA 1RF7A 5HUIA 3QLYA 3SH2A 4DPHA 1RD7A 3K47A 3NXOA 1VJ3A 4XECX 4DDRA 3D84X 3FRAX 1DLSA 2JYBA 1DR3A 3K45A 2AZNA 1M78A 4P3QA 4Q67A 3JWMA 3K2HA 4KJJA 3EEKA 4HA7A 4KAKA 4I13A 1VDRA 4EILA 3FRBX 5HI6A 1RX6A 4PSTA 1CZ3A 4QLFA 4H97A 4H96A 3M09A 4KL9A 1DR1A 4XT8A 1DISA 3F0XX 1RA9A 3SA2A 3E0BA 3NRRA 3S9UA 3DRCA 4Q0EA 4P68A 3F0BX 4KBNA 2W9GA 3F0VX 4P3RA 4ELEA 1LY3A 4NX6A 1J3IA 3FL9A 3FQCA 1DF7A 5HF2X 1DRBA 1OHKA 3FQ0A 3DL5A 5HT5A 3NU0A 3DAUA 4M6LA 3GHCA 4I1NA 1U71A 4PSSA 5FDAA 3NZ6X 4ECKA 2ANOA 4XT6A 3IX9A 4EIZA 1LUDA 8DFRA 5HF0X 4TU5X 1KMVA 3FQVA 3QLXA 2OBCA 1JOLA 3DATA 4RGCA 1ZDRA 1DHIA 1RX1A 4QI9A 4KLXA 3QLWA 5CC9A 3QL0A 4IXFX 3NZAX 3TD8A 4DPDA 2XW7A 4QHVA 4GH8A 4KM2A 3SAIA 2D0KA 1DYIA 4HOEA 5DXVA 4PTHA 3QYLA 1PD8A 3UM5A 4DP3A 3OCHA 3FYVX 4KEBA 2C2SA 3CSEA 2QK8A 1U72A 5JA3A 3DGAA 3S7AA 4ELBA 3FRFX 2W9SA 4QLEA 2HQPA 3KGYA 2CIGA 3RG9A 4X5GA 5U27A 3EX8A 1S3YA 1DG8A 3FS6A 3IRMA 4G95A 3I3RA 3TQ9A 1MVSA 3IA5A 3M08A 4M7VA 2C2TA 1DR4A 2W9TA 4FGGA 4X5HA 6DFRA 2D5NA 2BL9A 4LAHX 3NXVA 3NTZA 4KJLA 1M7AA 5EAJA 3D80A 5HSRA 3FQFA 3F0SX 1E26A 4M2XA 5ECCA 3FREX 3HJ3A 3Q1HA 3RO9A 3HBBA 7DFRA 2KGKA 3NXYA 4P66A 4LAEX 3K74A 4EJ1A 5CCCA 3IRNA 2BLAA 3JWFA 2FZIA 4X5JA 4PSYA 3SRSX 1U70A 4OR7A 4G8ZX 1RX7A 1S3VA 1RX2A 2DHFA 3IROA 2BLCA 3ZPCA 3L3RA 4QJZD 4OSGA 3SRUX 1DR7A 4QLGA 4DFRA 3DFRA 4PDJA 1D1GA 3KJSA 4ELFA 5HT4A 3NZDA 1PD9A 1RB2A 1DYHA 3NZ9X 3VCOA 2LF1A 4ELHA 2ZZAA 1DG7A 1DRAA 4XRBA 3QLRA 5HVEA 3DG8A 2O7PA 5JG0X 1J3JA 1RG7A 1HFPA 1DYRA 1RE7A 4M6JA 1KMSA 1DR5A 4ELGA 1YHOA 3KY8A 4KM0A 1M79A 4HOFA 1RX9A 3EELA 3ZPGA 5HSUA 1DREA 5ECXA 3TQBA 5HVBA 4CD2A 4FGHA 1J3KA 3JSUA 3KJRA 3JTWA 3SA1A 1S3WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HXV A;  3CLB A;  3F8Z A;  1IA2 A;  1HFQ A;  1LY4 A;  4KYA A;  3QL3 A;  3QGT A;  1PDB A;  1DG5 A;  3FQO A;  3CL9 A;  1DDS A;  1RH3 A;  3FYW X;  2DRC A;  2OIP A;  3SGY A;  4H95 A;  4KD7 A;  2W3M A;  1DIU A;  1BOZ A;  3SR5 X;  4HOG A;  1DR2 A;  1DRH A;  3QG2 A;  3UM8 A;  2ITH A;  5E8Q A;  1DRF A;  3JVX A;  1AO8 A;  3KFY A;  1JUV A;  2W3V A;  1OHJ A;  3FQZ A;  4NX7 A;  3F0U X;  3TQA A;  3EIG A;  5HPB A;  1BZF A;  1AOE A;  4LEK X;  4KY4 A;  3FY9 X;  4X5I A;  1RA8 A;  2INQ A;  4Q0D A;  3LG4 A;  2B3Z A;  4XT7 A;  1RX3 A;  4KNE A;  3NXR A;  3S3V A;  3DL6 A;  1TDR A;  1JOM A;  4G3M A;  4M6K A;  4XE6 X;  3SRQ X;  3R33 A;  1DHF A;  3INV A;  2FZJ A;  2P4G A;  1HFR A;  4IXG X;  4EIG A;  1RX4 A;  2G6V A;  5U26 A;  1RX5 A;  2HM9 A;  3GHW A;  1S3U A;  1RC4 A;  1DLR A;  2W3W A;  3ROA A;  3UM6 A;  3JWK A;  3F8Y A;  1IA3 A;  3JWC A;  1KLK A;  2ANQ A;  3EEM A;  3OAF A;  1RA3 A;  3NZC X;  1DR6 A;  3GI2 A;  1DYJ A;  3EEJ A;  3IA4 A;  4FHB A;  2L28 A;  1CD2 A;  1RB3 A;  4X5F A;  5HQY A;  2W9H A;  3FL8 A;  4Q6A A;  1DDR A;  2W3B A;  3FY8 X;  1RX8 A;  2GD9 A;  4QJC A;  3TQ8 A;  4IXE D;  3F0Q X;  2CD2 A;  1AI9 A;  3I8A X;  4KFJ A;  5HQZ A;  3SRW X;  1RA2 A;  3NZB X;  1MVT A;  1IA1 A;  3QFX A;  4LAG X;  3F91 A;  3SRR X;  3N0H A;  4PTJ A;  1QZF A;  3FRD X;  3NXX A;  3QLS A;  4XT5 A;  4KY8 A;  3JW3 A;  3SQY X;  1SEJ A;  4XT4 A;  4M7U A;  3JW5 A;  1RA1 A;  2BLB A;  3NXT A;  1IA4 A;  4H98 A;  1DHJ A;  3QLZ A;  5DFR A;  2W3A A;  3CD2 A;  4KJK A;  2H2Q A;  3QYO A;  1DAJ A;  4HA9 A;  3GYF A;  3GHV A;  2FZH A;  1RF7 A;  5HUI A;  3QLY A;  3SH2 A;  4DPH A;  1RD7 A;  3K47 A;  3NXO A;  1VJ3 A;  4XEC X;  4DDR A;  3D84 X;  3FRA X;  1DLS A;  2JYB A;  1DR3 A;  3K45 A;  2AZN A;  1M78 A;  4P3Q A;  4Q67 A;  3JWM A;  3K2H A;  4KJJ A;  3EEK A;  4HA7 A;  4KAK A;  4I13 A;  1VDR A;  4EIL A;  3FRB X;  5HI6 A;  1RX6 A;  4PST A;  1CZ3 A;  4QLF A;  4H97 A;  4H96 A;  3M09 A;  4KL9 A;  1DR1 A;  4XT8 A;  1DIS A;  3F0X X;  1RA9 A;  3SA2 A;  3E0B A;  3NRR A;  3S9U A;  3DRC A;  4Q0E A;  4P68 A;  3F0B X;  4KBN A;  2W9G A;  3F0V X;  4P3R A;  4ELE A;  1LY3 A;  4NX6 A;  1J3I A;  3FL9 A;  3FQC A;  1DF7 A;  5HF2 X;  1DRB A;  1OHK A;  3FQ0 A;  3DL5 A;  5HT5 A;  3NU0 A;  3DAU A;  4M6L A;  3GHC A;  4I1N A;  1U71 A;  4PSS A;  5FDA A;  3NZ6 X;  4ECK A;  2ANO A;  4XT6 A;  3IX9 A;  4EIZ A;  1LUD A;  8DFR A;  5HF0 X;  4TU5 X;  1KMV A;  3FQV A;  3QLX A;  2OBC A;  1JOL A;  3DAT A;  4RGC A;  1ZDR A;  1DHI A;  1RX1 A;  4QI9 A;  4KLX A;  3QLW A;  5CC9 A;  3QL0 A;  4IXF X;  3NZA X;  3TD8 A;  4DPD A;  2XW7 A;  4QHV A;  4GH8 A;  4KM2 A;  3SAI A;  2D0K A;  1DYI A;  4HOE A;  5DXV A;  4PTH A;  3QYL A;  1PD8 A;  3UM5 A;  4DP3 A;  3OCH A;  3FYV X;  4KEB A;  2C2S A;  3CSE A;  2QK8 A;  1U72 A;  5JA3 A;  3DGA A;  3S7A A;  4ELB A;  3FRF X;  2W9S A;  4QLE A;  2HQP A;  3KGY A;  2CIG A;  3RG9 A;  4X5G A;  5U27 A;  3EX8 A;  1S3Y A;  1DG8 A;  3FS6 A;  3IRM A;  4G95 A;  3I3R A;  3TQ9 A;  1MVS A;  3IA5 A;  3M08 A;  4M7V A;  2C2T A;  1DR4 A;  2W9T A;  4FGG A;  4X5H A;  6DFR A;  2D5N A;  2BL9 A;  4LAH X;  3NXV A;  3NTZ A;  4KJL A;  1M7A A;  5EAJ A;  3D80 A;  5HSR A;  3FQF A;  3F0S X;  1E26 A;  4M2X A;  5ECC A;  3FRE X;  3HJ3 A;  3Q1H A;  3RO9 A;  3HBB A;  7DFR A;  2KGK A;  3NXY A;  4P66 A;  4LAE X;  3K74 A;  4EJ1 A;  5CCC A;  3IRN A;  2BLA A;  3JWF A;  2FZI A;  4X5J A;  4PSY A;  3SRS X;  1U70 A;  4OR7 A;  4G8Z X;  1RX7 A;  1S3V A;  1RX2 A;  2DHF A;  3IRO A;  2BLC A;  3ZPC A;  3L3R A;  4QJZ D;  4OSG A;  3SRU X;  1DR7 A;  4QLG A;  4DFR A;  3DFR A;  4PDJ A;  1D1G A;  3KJS A;  4ELF A;  5HT4 A;  3NZD A;  1PD9 A;  1RB2 A;  1DYH A;  3NZ9 X;  3VCO A;  2LF1 A;  4ELH A;  2ZZA A;  1DG7 A;  1DRA A;  4XRB A;  3QLR A;  5HVE A;  3DG8 A;  2O7P A;  5JG0 X;  1J3J A;  1RG7 A;  1HFP A;  1DYR A;  1RE7 A;  4M6J A;  1KMS A;  1DR5 A;  4ELG A;  1YHO A;  3KY8 A;  4KM0 A;  1M79 A;  4HOF A;  1RX9 A;  3EEL A;  3ZPG A;  5HSU A;  1DRE A;  5ECX A;  3TQB A;  5HVB A;  4CD2 A;  4FGH A;  1J3K A;  3JSU A;  3KJR A;  3JTW A;  3SA1 A;  1S3W A; 
#chains in the Genus database with same CATH topology
 2HXV A;  3CLB A;  3F8Z A;  1IA2 A;  1HFQ A;  1LY4 A;  4KYA A;  3QL3 A;  3QGT A;  1PDB A;  1DG5 A;  3FQO A;  3CL9 A;  1DDS A;  1RH3 A;  3FYW X;  2DRC A;  2OIP A;  3SGY A;  4H95 A;  4KD7 A;  2W3M A;  1DIU A;  1BOZ A;  3SR5 X;  4HOG A;  1DR2 A;  1DRH A;  3QG2 A;  3UM8 A;  2ITH A;  5E8Q A;  1DRF A;  3JVX A;  1AO8 A;  3KFY A;  1JUV A;  2W3V A;  1OHJ A;  3FQZ A;  4NX7 A;  3F0U X;  3TQA A;  3EIG A;  5HPB A;  1BZF A;  1AOE A;  4LEK X;  4KY4 A;  3FY9 X;  4X5I A;  1RA8 A;  2INQ A;  4Q0D A;  3LG4 A;  2B3Z A;  4XT7 A;  1RX3 A;  4KNE A;  3NXR A;  3S3V A;  3DL6 A;  1TDR A;  1JOM A;  4G3M A;  4M6K A;  4XE6 X;  3SRQ X;  3R33 A;  1DHF A;  3INV A;  2FZJ A;  2P4G A;  1HFR A;  4IXG X;  4EIG A;  1RX4 A;  2G6V A;  5U26 A;  1RX5 A;  2HM9 A;  3GHW A;  1S3U A;  1RC4 A;  1DLR A;  2W3W A;  3ROA A;  3UM6 A;  3JWK A;  3F8Y A;  1IA3 A;  3JWC A;  1KLK A;  2ANQ A;  3EEM A;  3OAF A;  1RA3 A;  3NZC X;  1DR6 A;  3GI2 A;  1DYJ A;  3EEJ A;  3IA4 A;  4FHB A;  2L28 A;  1CD2 A;  1RB3 A;  4X5F A;  5HQY A;  2W9H A;  3FL8 A;  4Q6A A;  1DDR A;  2W3B A;  3FY8 X;  1RX8 A;  2GD9 A;  4QJC A;  3TQ8 A;  4IXE D;  3F0Q X;  2CD2 A;  1AI9 A;  3I8A X;  4KFJ A;  5HQZ A;  3SRW X;  1RA2 A;  3NZB X;  1MVT A;  1IA1 A;  3QFX A;  4LAG X;  3F91 A;  3SRR X;  3N0H A;  4PTJ A;  1QZF A;  3FRD X;  3NXX A;  3QLS A;  4XT5 A;  4KY8 A;  3JW3 A;  3SQY X;  1SEJ A;  4XT4 A;  4M7U A;  3JW5 A;  1RA1 A;  2BLB A;  3NXT A;  1IA4 A;  4H98 A;  1DHJ A;  3QLZ A;  5DFR A;  2W3A A;  3CD2 A;  4KJK A;  2H2Q A;  3QYO A;  1DAJ A;  4HA9 A;  3GYF A;  3GHV A;  2FZH A;  1RF7 A;  5HUI A;  3QLY A;  3SH2 A;  4DPH A;  1RD7 A;  3K47 A;  3NXO A;  1VJ3 A;  4XEC X;  4DDR A;  3D84 X;  3FRA X;  1DLS A;  2JYB A;  1DR3 A;  3K45 A;  2AZN A;  1M78 A;  4P3Q A;  4Q67 A;  3JWM A;  3K2H A;  4KJJ A;  3EEK A;  4HA7 A;  4KAK A;  4I13 A;  1VDR A;  4EIL A;  3FRB X;  5HI6 A;  1RX6 A;  4PST A;  1CZ3 A;  4QLF A;  4H97 A;  4H96 A;  3M09 A;  4KL9 A;  1DR1 A;  4XT8 A;  1DIS A;  3F0X X;  1RA9 A;  3SA2 A;  3E0B A;  3NRR A;  3S9U A;  3DRC A;  4Q0E A;  4P68 A;  3F0B X;  4KBN A;  2W9G A;  3F0V X;  4P3R A;  4ELE A;  1LY3 A;  4NX6 A;  1J3I A;  3FL9 A;  3FQC A;  1DF7 A;  5HF2 X;  1DRB A;  1OHK A;  3FQ0 A;  3DL5 A;  5HT5 A;  3NU0 A;  3DAU A;  4M6L A;  3GHC A;  4I1N A;  1U71 A;  4PSS A;  5FDA A;  3NZ6 X;  4ECK A;  2ANO A;  4XT6 A;  3IX9 A;  4EIZ A;  1LUD A;  8DFR A;  5HF0 X;  4TU5 X;  1KMV A;  3FQV A;  3QLX A;  2OBC A;  1JOL A;  3DAT A;  4RGC A;  1ZDR A;  1DHI A;  1RX1 A;  4QI9 A;  4KLX A;  3QLW A;  5CC9 A;  3QL0 A;  4IXF X;  3NZA X;  3TD8 A;  4DPD A;  2XW7 A;  4QHV A;  4GH8 A;  4KM2 A;  3SAI A;  2D0K A;  1DYI A;  4HOE A;  5DXV A;  4PTH A;  3QYL A;  1PD8 A;  3UM5 A;  4DP3 A;  3OCH A;  3FYV X;  4KEB A;  2C2S A;  3CSE A;  2QK8 A;  1U72 A;  5JA3 A;  3DGA A;  3S7A A;  4ELB A;  3FRF X;  2W9S A;  4QLE A;  2HQP A;  3KGY A;  2CIG A;  3RG9 A;  4X5G A;  5U27 A;  3EX8 A;  1S3Y A;  1DG8 A;  3FS6 A;  3IRM A;  4G95 A;  3I3R A;  3TQ9 A;  1MVS A;  3IA5 A;  3M08 A;  4M7V A;  2C2T A;  1DR4 A;  2W9T A;  4FGG A;  4X5H A;  6DFR A;  2D5N A;  2BL9 A;  4LAH X;  3NXV A;  3NTZ A;  4KJL A;  1M7A A;  5EAJ A;  3D80 A;  5HSR A;  3FQF A;  3F0S X;  1E26 A;  4M2X A;  5ECC A;  3FRE X;  3HJ3 A;  3Q1H A;  3RO9 A;  3HBB A;  7DFR A;  2KGK A;  3NXY A;  4P66 A;  4LAE X;  3K74 A;  4EJ1 A;  5CCC A;  3IRN A;  2BLA A;  3JWF A;  2FZI A;  4X5J A;  4PSY A;  3SRS X;  1U70 A;  4OR7 A;  4G8Z X;  1RX7 A;  1S3V A;  1RX2 A;  2DHF A;  3IRO A;  2BLC A;  3ZPC A;  3L3R A;  4QJZ D;  4OSG A;  3SRU X;  1DR7 A;  4QLG A;  4DFR A;  3DFR A;  4PDJ A;  1D1G A;  3KJS A;  4ELF A;  5HT4 A;  3NZD A;  1PD9 A;  1RB2 A;  1DYH A;  3NZ9 X;  3VCO A;  2LF1 A;  4ELH A;  2ZZA A;  1DG7 A;  1DRA A;  4XRB A;  3QLR A;  5HVE A;  3DG8 A;  2O7P A;  5JG0 X;  1J3J A;  1RG7 A;  1HFP A;  1DYR A;  1RE7 A;  4M6J A;  1KMS A;  1DR5 A;  4ELG A;  1YHO A;  3KY8 A;  4KM0 A;  1M79 A;  4HOF A;  1RX9 A;  3EEL A;  3ZPG A;  5HSU A;  1DRE A;  5ECX A;  3TQB A;  5HVB A;  4CD2 A;  4FGH A;  1J3K A;  3JSU A;  3KJR A;  3JTW A;  3SA1 A;  1S3W A; 
#chains in the Genus database with same CATH homology
 2HXV A;  3CLB A;  3F8Z A;  1IA2 A;  1HFQ A;  1LY4 A;  4KYA A;  3QL3 A;  3QGT A;  1PDB A;  1DG5 A;  3FQO A;  3CL9 A;  1DDS A;  1RH3 A;  3FYW X;  2DRC A;  2OIP A;  3SGY A;  4H95 A;  4KD7 A;  2W3M A;  1DIU A;  1BOZ A;  3SR5 X;  4HOG A;  1DR2 A;  1DRH A;  3QG2 A;  3UM8 A;  2ITH A;  5E8Q A;  1DRF A;  3JVX A;  1AO8 A;  3KFY A;  1JUV A;  2W3V A;  1OHJ A;  3FQZ A;  4NX7 A;  3F0U X;  3TQA A;  3EIG A;  5HPB A;  1BZF A;  1AOE A;  4LEK X;  4KY4 A;  3FY9 X;  4X5I A;  1RA8 A;  2INQ A;  4Q0D A;  3LG4 A;  2B3Z A;  4XT7 A;  1RX3 A;  4KNE A;  3NXR A;  3S3V A;  3DL6 A;  1TDR A;  1JOM A;  4G3M A;  4M6K A;  4XE6 X;  3SRQ X;  3R33 A;  1DHF A;  3INV A;  2FZJ A;  2P4G A;  1HFR A;  4IXG X;  4EIG A;  1RX4 A;  2G6V A;  5U26 A;  1RX5 A;  2HM9 A;  3GHW A;  1S3U A;  1RC4 A;  1DLR A;  2W3W A;  3ROA A;  3UM6 A;  3JWK A;  3F8Y A;  1IA3 A;  3JWC A;  1KLK A;  2ANQ A;  3EEM A;  3OAF A;  1RA3 A;  3NZC X;  1DR6 A;  3GI2 A;  1DYJ A;  3EEJ A;  3IA4 A;  4FHB A;  2L28 A;  1CD2 A;  1RB3 A;  4X5F A;  5HQY A;  2W9H A;  3FL8 A;  4Q6A A;  1DDR A;  2W3B A;  3FY8 X;  1RX8 A;  2GD9 A;  4QJC A;  3TQ8 A;  4IXE D;  3F0Q X;  2CD2 A;  1AI9 A;  3I8A X;  4KFJ A;  5HQZ A;  3SRW X;  1RA2 A;  3NZB X;  1MVT A;  1IA1 A;  3QFX A;  4LAG X;  3F91 A;  3SRR X;  3N0H A;  4PTJ A;  1QZF A;  3FRD X;  3NXX A;  3QLS A;  4XT5 A;  4KY8 A;  3JW3 A;  3SQY X;  1SEJ A;  4XT4 A;  4M7U A;  3JW5 A;  1RA1 A;  2BLB A;  3NXT A;  1IA4 A;  4H98 A;  1DHJ A;  3QLZ A;  5DFR A;  2W3A A;  3CD2 A;  4KJK A;  2H2Q A;  3QYO A;  1DAJ A;  4HA9 A;  3GYF A;  3GHV A;  2FZH A;  1RF7 A;  5HUI A;  3QLY A;  3SH2 A;  4DPH A;  1RD7 A;  3K47 A;  3NXO A;  1VJ3 A;  4XEC X;  4DDR A;  3D84 X;  3FRA X;  1DLS A;  2JYB A;  1DR3 A;  3K45 A;  2AZN A;  1M78 A;  4P3Q A;  4Q67 A;  3JWM A;  3K2H A;  4KJJ A;  3EEK A;  4HA7 A;  4KAK A;  4I13 A;  1VDR A;  4EIL A;  3FRB X;  5HI6 A;  1RX6 A;  4PST A;  1CZ3 A;  4QLF A;  4H97 A;  4H96 A;  3M09 A;  4KL9 A;  1DR1 A;  4XT8 A;  1DIS A;  3F0X X;  1RA9 A;  3SA2 A;  3E0B A;  3NRR A;  3S9U A;  3DRC A;  4Q0E A;  4P68 A;  3F0B X;  4KBN A;  2W9G A;  3F0V X;  4P3R A;  4ELE A;  1LY3 A;  4NX6 A;  1J3I A;  3FL9 A;  3FQC A;  1DF7 A;  5HF2 X;  1DRB A;  1OHK A;  3FQ0 A;  3DL5 A;  5HT5 A;  3NU0 A;  3DAU A;  4M6L A;  3GHC A;  4I1N A;  1U71 A;  4PSS A;  5FDA A;  3NZ6 X;  4ECK A;  2ANO A;  4XT6 A;  3IX9 A;  4EIZ A;  1LUD A;  8DFR A;  5HF0 X;  4TU5 X;  1KMV A;  3FQV A;  3QLX A;  2OBC A;  1JOL A;  3DAT A;  4RGC A;  1ZDR A;  1DHI A;  1RX1 A;  4QI9 A;  4KLX A;  3QLW A;  5CC9 A;  3QL0 A;  4IXF X;  3NZA X;  3TD8 A;  4DPD A;  2XW7 A;  4QHV A;  4GH8 A;  4KM2 A;  3SAI A;  2D0K A;  1DYI A;  4HOE A;  5DXV A;  4PTH A;  3QYL A;  1PD8 A;  3UM5 A;  4DP3 A;  3OCH A;  3FYV X;  4KEB A;  2C2S A;  3CSE A;  2QK8 A;  1U72 A;  5JA3 A;  3DGA A;  3S7A A;  4ELB A;  3FRF X;  2W9S A;  4QLE A;  2HQP A;  3KGY A;  2CIG A;  3RG9 A;  4X5G A;  5U27 A;  3EX8 A;  1S3Y A;  1DG8 A;  3FS6 A;  3IRM A;  4G95 A;  3I3R A;  3TQ9 A;  1MVS A;  3IA5 A;  3M08 A;  4M7V A;  2C2T A;  1DR4 A;  2W9T A;  4FGG A;  4X5H A;  6DFR A;  2D5N A;  2BL9 A;  4LAH X;  3NXV A;  3NTZ A;  4KJL A;  1M7A A;  5EAJ A;  3D80 A;  5HSR A;  3FQF A;  3F0S X;  1E26 A;  4M2X A;  5ECC A;  3FRE X;  3HJ3 A;  3Q1H A;  3RO9 A;  3HBB A;  7DFR A;  2KGK A;  3NXY A;  4P66 A;  4LAE X;  3K74 A;  4EJ1 A;  5CCC A;  3IRN A;  2BLA A;  3JWF A;  2FZI A;  4X5J A;  4PSY A;  3SRS X;  1U70 A;  4OR7 A;  4G8Z X;  1RX7 A;  1S3V A;  1RX2 A;  2DHF A;  3IRO A;  2BLC A;  3ZPC A;  3L3R A;  4QJZ D;  4OSG A;  3SRU X;  1DR7 A;  4QLG A;  4DFR A;  3DFR A;  4PDJ A;  1D1G A;  3KJS A;  4ELF A;  5HT4 A;  3NZD A;  1PD9 A;  1RB2 A;  1DYH A;  3NZ9 X;  3VCO A;  2LF1 A;  4ELH A;  2ZZA A;  1DG7 A;  1DRA A;  4XRB A;  3QLR A;  5HVE A;  3DG8 A;  2O7P A;  5JG0 X;  1J3J A;  1RG7 A;  1HFP A;  1DYR A;  1RE7 A;  4M6J A;  1KMS A;  1DR5 A;  4ELG A;  1YHO A;  3KY8 A;  4KM0 A;  1M79 A;  4HOF A;  1RX9 A;  3EEL A;  3ZPG A;  5HSU A;  1DRE A;  5ECX A;  3TQB A;  5HVB A;  4CD2 A;  4FGH A;  1J3K A;  3JSU A;  3KJR A;  3JTW A;  3SA1 A;  1S3W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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