3FQZA

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 40
204060801001201400510152025303540
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS6 (89-93)S1 (2-8)TI1 (9-12)S2 (13-15)O1 (113-115)TI'1 (16-19)TIV1 (15-18)AH1 (25-35)TI4 (142-145)S7 (107-113)TII2 (54-57)TII1 (35-38)S4 (58-62)S3 (39-43)AH2 (44-50)TI2 (65-68)S5 (74-76)TII3 (70-73)AH3 (95-102)S10 (149-156)TI3 (102-105)S8 (121-122)3H2 (128-130)S9 (131-139)3H1 (79-84)Updating...
connected with : NaN
publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 40
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fqzA00
3RG9A 2FZJA 1RA8A 1DR3A 3F0VX 4M2XA 4X5HA 3QL3A 3QGTA 4KD7A 3GYFA 1RX1A 3S3VA 4H98A 1DYIA 2O7PA 3F0BX 4XE6X 4EILA 3NU0A 4P66A 3FRFX 2GD9A 5E8QA 1RX7A 2DRCA 1VJ3A 4KJJA 3CD2A 1DR5A 5DXVA 4LAGX 1AOEA 3KY8A 5HF0X 3TQ9A 3SA2A 4EJ1A 1HFPA 4PSTA 2ZZAA 2HXVA 1HFRA 4TU5X 3SRWX 4Q0EA 1S3YA 8DFRA 4OSGA 3E0BA 4IXFX 3HJ3A 4P3QA 3K2HA 3SR5X 4IXGX 1DRFA 4HOFA 2ANOA 3FQ0A 3QLXA 2CIGA 3NXTA 4FHBA 1J3KA 4DFRA 3EELA 2W9HA 4G3MA 4XT5A 3F0SX 3QYLA 2D0KA 1J3IA 1CD2A 3GHCA 1KMVA 1RX5A 1DR2A 1E26A 3DRCA 5HI6A 6DFRA 3EX8A 3CSEA 4HA9A 5U26A 1IA1A 3IRMA 1RA2A 4H97A 4QLEA 1JOMA 2FZIA 5HT5A 3IA4A 3ROAA 3KGYA 3SRUX 4PDJA 3NZCX 2XW7A 1JUVA 1RA1A 3I3RA 3M08A 4P68A 3NZBX 5HF2X 3IRNA 1M7AA 1TDRA 3FQVA 3TQAA 2W3WA 4KBNA 3SH2A 3OAFA 4H95A 5EAJA 3CL9A 3FRAX 1M79A 4M6LA 3DGAA 5HQYA 3F8YA 3KJSA 4HOEA 1DYRA 3QYOA 3EIGA 1JOLA 1RH3A 4ELGA 4XRBA 3ZPGA 2C2SA 5JG0X 4ELFA 4ELHA 1PDBA 2W3VA 3SGYA 4KYAA 1DLSA 3SA1A 3Q1HA 1RX3A 3FY9X 3FL8A 1RX6A 1RX8A 1DYHA 3F0XX 1LY4A 3K45A 3JWKA 5HSRA 4M6KA 3CLBA 2CD2A 4M7UA 3QG2A 3NXXA 4X5FA 2W9TA 4FGHA 3FY8X 3K47A 3D80A 4PSYA 2P4GA 3TQBA 4GH8A 1ZDRA 1D1GA 3OCHA 3DL6A 2W3MA 2W3BA 1IA4A 4EIGA 3QLSA 3DATA 1RE7A 4FGGA 3NXOA 3N0HA 3NRRA 3FS6A 1AO8A 3FQZA 3R33A 5ECCA 1RB2A 1U70A 1U72A 3DAUA 3DL5A 4DDRA 3KFYA 4PTHA 5HSUA 1OHKA 3FYWX 3NXVA 5U27A 2LF1A 1S3UA 1DHFA 3S7AA 1QZFA 7DFRA 1DLRA 4KJKA 2BL9A 1RG7A 2C2TA 4ELBA 3KJRA 1CZ3A 2OBCA 4QLGA 1YHOA 3GI2A 1RC4A 2AZNA 3GHWA 4PTJA 3GHVA 4RGCA 1DG8A 1RA9A 4Q67A 1PD9A 3SRRX 3DFRA 4LAEX 5DFRA 1DRBA 3ZPCA 4I1NA 3FREX 4KM2A 1LY3A 3I8AX 1RA3A 4I13A 1DR7A 4QI9A 4KLXA 4XT6A 2BLAA 1DG7A 2B3ZA 4G95A 2JYBA 2H2QA 3SRSX 2BLBA 5CCCA 4X5IA 3F8ZA 4ECKA 2OIPA 4H96A 1MVTA 3NZ6X 3FQFA 2BLCA 2DHFA 4NX6A 1DRHA 2ANQA 1DHJA 4ELEA 2QK8A 5HT4A 5HUIA 1VDRA 3JVXA 4KAKA 4XECX 4DPHA 3JWMA 3TD8A 4LAHX 2HM9A 1KMSA 3FQOA 3INVA 3JTWA 1RB3A 3EEMA 4DPDA 1DRAA 4KY8A 3JWCA 4QJZD 1DR6A 1KLKA 3EEKA 3UM5A 3QLYA 1DF7A 4XT7A 3JSUA 4M6JA 3DG8A 3D84X 1BOZA 3F0QX 5HQZA 4M7VA 1M78A 3NZDA 1DIUA 1DISA 4QLFA 5JA3A 5CC9A 1RX2A 3EEJA 4LEKX 3QLWA 1SEJA 4EIZA 2KGKA 1HFQA 3IA5A 3FRDX 1S3VA 1U71A 3LG4A 3SRQX 1RD7A 4OR7A 1DREA 4P3RA 1DR1A 3VCOA 1DR4A 3FL9A 1J3JA 3NZAX 3FRBX 3QLZA 3JW3A 4X5JA 3UM6A 5HVEA 5ECXA 1DAJA 3UM8A 3NXYA 4DP3A 3JW5A 4HA7A 4XT4A 1DDRA 3QLRA 3NTZA 3QFXA 3TQ8A 3IX9A 2D5NA 4Q0DA 4HOGA 2W9SA 3JWFA 3M09A 4KY4A 1MVSA 4NX7A 4Q6AA 1IA2A 4KJLA 3NZ9X 1DHIA 2ITHA 2L28A 4QHVA 4QJCA 3S9UA 1DDSA 5HPBA 1PD8A 3L3RA 1S3WA 4G8ZX 2W3AA 1BZFA 4IXED 1RF7A 5HVBA 3F91A 4PSSA 1AI9A 1LUDA 3RO9A 4KM0A 4KFJA 3K74A 1RX4A 2HQPA 4KEBA 4CD2A 3SAIA 4XT8A 3NXRA 1OHJA 1DG5A 4KNEA 2W9GA 5FDAA 3IROA 2FZHA 3FQCA 3SQYX 1IA3A 1RX9A 3FYVX 2INQA 2G6VA 3F0UX 4KL9A 4X5GA 3QL0A 1DYJA 3HBBA
chains in the Genus database with same CATH superfamily
3RG9A 2FZJA 1RA8A 1DR3A 3F0VX 4M2XA 4X5HA 3QL3A 3QGTA 4KD7A 3GYFA 1RX1A 3S3VA 4H98A 1DYIA 2O7PA 3F0BX 4XE6X 4EILA 3NU0A 4P66A 3FRFX 2GD9A 5E8QA 1RX7A 2DRCA 1VJ3A 4KJJA 3CD2A 1DR5A 5DXVA 4LAGX 1AOEA 3KY8A 5HF0X 3TQ9A 3SA2A 4EJ1A 1HFPA 4PSTA 2ZZAA 2HXVA 1HFRA 4TU5X 3SRWX 4Q0EA 1S3YA 8DFRA 4OSGA 3E0BA 4IXFX 3HJ3A 4P3QA 3K2HA 3SR5X 4IXGX 1DRFA 4HOFA 2ANOA 3FQ0A 3QLXA 2CIGA 3NXTA 4FHBA 1J3KA 4DFRA 3EELA 2W9HA 4G3MA 4XT5A 3F0SX 3QYLA 2D0KA 1J3IA 1CD2A 3GHCA 1KMVA 1RX5A 1DR2A 1E26A 3DRCA 5HI6A 6DFRA 3EX8A 3CSEA 4HA9A 5U26A 1IA1A 3IRMA 1RA2A 4H97A 4QLEA 1JOMA 2FZIA 5HT5A 3IA4A 3ROAA 3KGYA 3SRUX 4PDJA 3NZCX 2XW7A 1JUVA 1RA1A 3I3RA 3M08A 4P68A 3NZBX 5HF2X 3IRNA 1M7AA 1TDRA 3FQVA 3TQAA 2W3WA 4KBNA 3SH2A 3OAFA 4H95A 5EAJA 3CL9A 3FRAX 1M79A 4M6LA 3DGAA 5HQYA 3F8YA 3KJSA 4HOEA 1DYRA 3QYOA 3EIGA 1JOLA 1RH3A 4ELGA 4XRBA 3ZPGA 2C2SA 5JG0X 4ELFA 4ELHA 1PDBA 2W3VA 3SGYA 4KYAA 1DLSA 3SA1A 3Q1HA 1RX3A 3FY9X 3FL8A 1RX6A 1RX8A 1DYHA 3F0XX 1LY4A 3K45A 3JWKA 5HSRA 4M6KA 3CLBA 2CD2A 4M7UA 3QG2A 3NXXA 4X5FA 2W9TA 4FGHA 3FY8X 3K47A 3D80A 4PSYA 2P4GA 3TQBA 4GH8A 1ZDRA 1D1GA 3OCHA 3DL6A 2W3MA 2W3BA 1IA4A 4EIGA 3QLSA 3DATA 1RE7A 4FGGA 3NXOA 3N0HA 3NRRA 3FS6A 1AO8A 3FQZA 3R33A 5ECCA 1RB2A 1U70A 1U72A 3DAUA 3DL5A 4DDRA 3KFYA 4PTHA 5HSUA 1OHKA 3FYWX 3NXVA 5U27A 2LF1A 1S3UA 1DHFA 3S7AA 1QZFA 7DFRA 1DLRA 4KJKA 2BL9A 1RG7A 2C2TA 4ELBA 3KJRA 1CZ3A 2OBCA 4QLGA 1YHOA 3GI2A 1RC4A 2AZNA 3GHWA 4PTJA 3GHVA 4RGCA 1DG8A 1RA9A 4Q67A 1PD9A 3SRRX 3DFRA 4LAEX 5DFRA 1DRBA 3ZPCA 4I1NA 3FREX 4KM2A 1LY3A 3I8AX 1RA3A 4I13A 1DR7A 4QI9A 4KLXA 4XT6A 2BLAA 1DG7A 2B3ZA 4G95A 2JYBA 2H2QA 3SRSX 2BLBA 5CCCA 4X5IA 3F8ZA 4ECKA 2OIPA 4H96A 1MVTA 3NZ6X 3FQFA 2BLCA 2DHFA 4NX6A 1DRHA 2ANQA 1DHJA 4ELEA 2QK8A 5HT4A 5HUIA 1VDRA 3JVXA 4KAKA 4XECX 4DPHA 3JWMA 3TD8A 4LAHX 2HM9A 1KMSA 3FQOA 3INVA 3JTWA 1RB3A 3EEMA 4DPDA 1DRAA 4KY8A 3JWCA 4QJZD 1DR6A 1KLKA 3EEKA 3UM5A 3QLYA 1DF7A 4XT7A 3JSUA 4M6JA 3DG8A 3D84X 1BOZA 3F0QX 5HQZA 4M7VA 1M78A 3NZDA 1DIUA 1DISA 4QLFA 5JA3A 5CC9A 1RX2A 3EEJA 4LEKX 3QLWA 1SEJA 4EIZA 2KGKA 1HFQA 3IA5A 3FRDX 1S3VA 1U71A 3LG4A 3SRQX 1RD7A 4OR7A 1DREA 4P3RA 1DR1A 3VCOA 1DR4A 3FL9A 1J3JA 3NZAX 3FRBX 3QLZA 3JW3A 4X5JA 3UM6A 5HVEA 5ECXA 1DAJA 3UM8A 3NXYA 4DP3A 3JW5A 4HA7A 4XT4A 1DDRA 3QLRA 3NTZA 3QFXA 3TQ8A 3IX9A 2D5NA 4Q0DA 4HOGA 2W9SA 3JWFA 3M09A 4KY4A 1MVSA 4NX7A 4Q6AA 1IA2A 4KJLA 3NZ9X 1DHIA 2ITHA 2L28A 4QHVA 4QJCA 3S9UA 1DDSA 5HPBA 1PD8A 3L3RA 1S3WA 4G8ZX 2W3AA 1BZFA 4IXED 1RF7A 5HVBA 3F91A 4PSSA 1AI9A 1LUDA 3RO9A 4KM0A 4KFJA 3K74A 1RX4A 2HQPA 4KEBA 4CD2A 3SAIA 4XT8A 3NXRA 1OHJA 1DG5A 4KNEA 2W9GA 5FDAA 3IROA 2FZHA 3FQCA 3SQYX 1IA3A 1RX9A 3FYVX 2INQA 2G6VA 3F0UX 4KL9A 4X5GA 3QL0A 1DYJA 3HBBA
chains in the Genus database with same CATH topology
3RG9A 2FZJA 1RA8A 1DR3A 3F0VX 4M2XA 4X5HA 3QL3A 3QGTA 4KD7A 3GYFA 1RX1A 3S3VA 4H98A 1DYIA 2O7PA 3F0BX 4XE6X 4EILA 3NU0A 4P66A 3FRFX 2GD9A 5E8QA 1RX7A 2DRCA 1VJ3A 4KJJA 3CD2A 1DR5A 5DXVA 4LAGX 1AOEA 3KY8A 5HF0X 3TQ9A 3SA2A 4EJ1A 1HFPA 4PSTA 2ZZAA 2HXVA 1HFRA 4TU5X 3SRWX 4Q0EA 1S3YA 8DFRA 4OSGA 3E0BA 4IXFX 3HJ3A 4P3QA 3K2HA 3SR5X 4IXGX 1DRFA 4HOFA 2ANOA 3FQ0A 3QLXA 2CIGA 3NXTA 4FHBA 1J3KA 4DFRA 3EELA 2W9HA 4G3MA 4XT5A 3F0SX 3QYLA 2D0KA 1J3IA 1CD2A 3GHCA 1KMVA 1RX5A 1DR2A 1E26A 3DRCA 5HI6A 6DFRA 3EX8A 3CSEA 4HA9A 5U26A 1IA1A 3IRMA 1RA2A 4H97A 4QLEA 1JOMA 2FZIA 5HT5A 3IA4A 3ROAA 3KGYA 3SRUX 4PDJA 3NZCX 2XW7A 1JUVA 1RA1A 3I3RA 3M08A 4P68A 3NZBX 5HF2X 3IRNA 1M7AA 1TDRA 3FQVA 3TQAA 2W3WA 4KBNA 3SH2A 3OAFA 4H95A 5EAJA 3CL9A 3FRAX 1M79A 4M6LA 3DGAA 5HQYA 3F8YA 3KJSA 4HOEA 1DYRA 3QYOA 3EIGA 1JOLA 1RH3A 4ELGA 4XRBA 3ZPGA 2C2SA 5JG0X 4ELFA 4ELHA 1PDBA 2W3VA 3SGYA 4KYAA 1DLSA 3SA1A 3Q1HA 1RX3A 3FY9X 3FL8A 1RX6A 1RX8A 1DYHA 3F0XX 1LY4A 3K45A 3JWKA 5HSRA 4M6KA 3CLBA 2CD2A 4M7UA 3QG2A 3NXXA 4X5FA 2W9TA 4FGHA 3FY8X 3K47A 3D80A 4PSYA 2P4GA 3TQBA 4GH8A 1ZDRA 1D1GA 3OCHA 3DL6A 2W3MA 2W3BA 1IA4A 4EIGA 3QLSA 3DATA 1RE7A 4FGGA 3NXOA 3N0HA 3NRRA 3FS6A 1AO8A 3FQZA 3R33A 5ECCA 1RB2A 1U70A 1U72A 3DAUA 3DL5A 4DDRA 3KFYA 4PTHA 5HSUA 1OHKA 3FYWX 3NXVA 5U27A 2LF1A 1S3UA 1DHFA 3S7AA 1QZFA 7DFRA 1DLRA 4KJKA 2BL9A 1RG7A 2C2TA 4ELBA 3KJRA 1CZ3A 2OBCA 4QLGA 1YHOA 3GI2A 1RC4A 2AZNA 3GHWA 4PTJA 3GHVA 4RGCA 1DG8A 1RA9A 4Q67A 1PD9A 3SRRX 3DFRA 4LAEX 5DFRA 1DRBA 3ZPCA 4I1NA 3FREX 4KM2A 1LY3A 3I8AX 1RA3A 4I13A 1DR7A 4QI9A 4KLXA 4XT6A 2BLAA 1DG7A 2B3ZA 4G95A 2JYBA 2H2QA 3SRSX 2BLBA 5CCCA 4X5IA 3F8ZA 4ECKA 2OIPA 4H96A 1MVTA 3NZ6X 3FQFA 2BLCA 2DHFA 4NX6A 1DRHA 2ANQA 1DHJA 4ELEA 2QK8A 5HT4A 5HUIA 1VDRA 3JVXA 4KAKA 4XECX 4DPHA 3JWMA 3TD8A 4LAHX 2HM9A 1KMSA 3FQOA 3INVA 3JTWA 1RB3A 3EEMA 4DPDA 1DRAA 4KY8A 3JWCA 4QJZD 1DR6A 1KLKA 3EEKA 3UM5A 3QLYA 1DF7A 4XT7A 3JSUA 4M6JA 3DG8A 3D84X 1BOZA 3F0QX 5HQZA 4M7VA 1M78A 3NZDA 1DIUA 1DISA 4QLFA 5JA3A 5CC9A 1RX2A 3EEJA 4LEKX 3QLWA 1SEJA 4EIZA 2KGKA 1HFQA 3IA5A 3FRDX 1S3VA 1U71A 3LG4A 3SRQX 1RD7A 4OR7A 1DREA 4P3RA 1DR1A 3VCOA 1DR4A 3FL9A 1J3JA 3NZAX 3FRBX 3QLZA 3JW3A 4X5JA 3UM6A 5HVEA 5ECXA 1DAJA 3UM8A 3NXYA 4DP3A 3JW5A 4HA7A 4XT4A 1DDRA 3QLRA 3NTZA 3QFXA 3TQ8A 3IX9A 2D5NA 4Q0DA 4HOGA 2W9SA 3JWFA 3M09A 4KY4A 1MVSA 4NX7A 4Q6AA 1IA2A 4KJLA 3NZ9X 1DHIA 2ITHA 2L28A 4QHVA 4QJCA 3S9UA 1DDSA 5HPBA 1PD8A 3L3RA 1S3WA 4G8ZX 2W3AA 1BZFA 4IXED 1RF7A 5HVBA 3F91A 4PSSA 1AI9A 1LUDA 3RO9A 4KM0A 4KFJA 3K74A 1RX4A 2HQPA 4KEBA 4CD2A 3SAIA 4XT8A 3NXRA 1OHJA 1DG5A 4KNEA 2W9GA 5FDAA 3IROA 2FZHA 3FQCA 3SQYX 1IA3A 1RX9A 3FYVX 2INQA 2G6VA 3F0UX 4KL9A 4X5GA 3QL0A 1DYJA 3HBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RG9 A;  2FZJ A;  1RA8 A;  1DR3 A;  3F0V X;  4M2X A;  4X5H A;  3QL3 A;  3QGT A;  4KD7 A;  3GYF A;  1RX1 A;  3S3V A;  4H98 A;  1DYI A;  2O7P A;  3F0B X;  4XE6 X;  4EIL A;  3NU0 A;  4P66 A;  3FRF X;  2GD9 A;  5E8Q A;  1RX7 A;  2DRC A;  1VJ3 A;  4KJJ A;  3CD2 A;  1DR5 A;  5DXV A;  4LAG X;  1AOE A;  3KY8 A;  5HF0 X;  3TQ9 A;  3SA2 A;  4EJ1 A;  1HFP A;  4PST A;  2ZZA A;  2HXV A;  1HFR A;  4TU5 X;  3SRW X;  4Q0E A;  1S3Y A;  8DFR A;  4OSG A;  3E0B A;  4IXF X;  3HJ3 A;  4P3Q A;  3K2H A;  3SR5 X;  4IXG X;  1DRF A;  4HOF A;  2ANO A;  3FQ0 A;  3QLX A;  2CIG A;  3NXT A;  4FHB A;  1J3K A;  4DFR A;  3EEL A;  2W9H A;  4G3M A;  4XT5 A;  3F0S X;  3QYL A;  2D0K A;  1J3I A;  1CD2 A;  3GHC A;  1KMV A;  1RX5 A;  1DR2 A;  1E26 A;  3DRC A;  5HI6 A;  6DFR A;  3EX8 A;  3CSE A;  4HA9 A;  5U26 A;  1IA1 A;  3IRM A;  1RA2 A;  4H97 A;  4QLE A;  1JOM A;  2FZI A;  5HT5 A;  3IA4 A;  3ROA A;  3KGY A;  3SRU X;  4PDJ A;  3NZC X;  2XW7 A;  1JUV A;  1RA1 A;  3I3R A;  3M08 A;  4P68 A;  3NZB X;  5HF2 X;  3IRN A;  1M7A A;  1TDR A;  3FQV A;  3TQA A;  2W3W A;  4KBN A;  3SH2 A;  3OAF A;  4H95 A;  5EAJ A;  3CL9 A;  3FRA X;  1M79 A;  4M6L A;  3DGA A;  5HQY A;  3F8Y A;  3KJS A;  4HOE A;  1DYR A;  3QYO A;  3EIG A;  1JOL A;  1RH3 A;  4ELG A;  4XRB A;  3ZPG A;  2C2S A;  5JG0 X;  4ELF A;  4ELH A;  1PDB A;  2W3V A;  3SGY A;  4KYA A;  1DLS A;  3SA1 A;  3Q1H A;  1RX3 A;  3FY9 X;  3FL8 A;  1RX6 A;  1RX8 A;  1DYH A;  3F0X X;  1LY4 A;  3K45 A;  3JWK A;  5HSR A;  4M6K A;  3CLB A;  2CD2 A;  4M7U A;  3QG2 A;  3NXX A;  4X5F A;  2W9T A;  4FGH A;  3FY8 X;  3K47 A;  3D80 A;  4PSY A;  2P4G A;  3TQB A;  4GH8 A;  1ZDR A;  1D1G A;  3OCH A;  3DL6 A;  2W3M A;  2W3B A;  1IA4 A;  4EIG A;  3QLS A;  3DAT A;  1RE7 A;  4FGG A;  3NXO A;  3N0H A;  3NRR A;  3FS6 A;  1AO8 A;  3FQZ A;  3R33 A;  5ECC A;  1RB2 A;  1U70 A;  1U72 A;  3DAU A;  3DL5 A;  4DDR A;  3KFY A;  4PTH A;  5HSU A;  1OHK A;  3FYW X;  3NXV A;  5U27 A;  2LF1 A;  1S3U A;  1DHF A;  3S7A A;  1QZF A;  7DFR A;  1DLR A;  4KJK A;  2BL9 A;  1RG7 A;  2C2T A;  4ELB A;  3KJR A;  1CZ3 A;  2OBC A;  4QLG A;  1YHO A;  3GI2 A;  1RC4 A;  2AZN A;  3GHW A;  4PTJ A;  3GHV A;  4RGC A;  1DG8 A;  1RA9 A;  4Q67 A;  1PD9 A;  3SRR X;  3DFR A;  4LAE X;  5DFR A;  1DRB A;  3ZPC A;  4I1N A;  3FRE X;  4KM2 A;  1LY3 A;  3I8A X;  1RA3 A;  4I13 A;  1DR7 A;  4QI9 A;  4KLX A;  4XT6 A;  2BLA A;  1DG7 A;  2B3Z A;  4G95 A;  2JYB A;  2H2Q A;  3SRS X;  2BLB A;  5CCC A;  4X5I A;  3F8Z A;  4ECK A;  2OIP A;  4H96 A;  1MVT A;  3NZ6 X;  3FQF A;  2BLC A;  2DHF A;  4NX6 A;  1DRH A;  2ANQ A;  1DHJ A;  4ELE A;  2QK8 A;  5HT4 A;  5HUI A;  1VDR A;  3JVX A;  4KAK A;  4XEC X;  4DPH A;  3JWM A;  3TD8 A;  4LAH X;  2HM9 A;  1KMS A;  3FQO A;  3INV A;  3JTW A;  1RB3 A;  3EEM A;  4DPD A;  1DRA A;  4KY8 A;  3JWC A;  4QJZ D;  1DR6 A;  1KLK A;  3EEK A;  3UM5 A;  3QLY A;  1DF7 A;  4XT7 A;  3JSU A;  4M6J A;  3DG8 A;  3D84 X;  1BOZ A;  3F0Q X;  5HQZ A;  4M7V A;  1M78 A;  3NZD A;  1DIU A;  1DIS A;  4QLF A;  5JA3 A;  5CC9 A;  1RX2 A;  3EEJ A;  4LEK X;  3QLW A;  1SEJ A;  4EIZ A;  2KGK A;  1HFQ A;  3IA5 A;  3FRD X;  1S3V A;  1U71 A;  3LG4 A;  3SRQ X;  1RD7 A;  4OR7 A;  1DRE A;  4P3R A;  1DR1 A;  3VCO A;  1DR4 A;  3FL9 A;  1J3J A;  3NZA X;  3FRB X;  3QLZ A;  3JW3 A;  4X5J A;  3UM6 A;  5HVE A;  5ECX A;  1DAJ A;  3UM8 A;  3NXY A;  4DP3 A;  3JW5 A;  4HA7 A;  4XT4 A;  1DDR A;  3QLR A;  3NTZ A;  3QFX A;  3TQ8 A;  3IX9 A;  2D5N A;  4Q0D A;  4HOG A;  2W9S A;  3JWF A;  3M09 A;  4KY4 A;  1MVS A;  4NX7 A;  4Q6A A;  1IA2 A;  4KJL A;  3NZ9 X;  1DHI A;  2ITH A;  2L28 A;  4QHV A;  4QJC A;  3S9U A;  1DDS A;  5HPB A;  1PD8 A;  3L3R A;  1S3W A;  4G8Z X;  2W3A A;  1BZF A;  4IXE D;  1RF7 A;  5HVB A;  3F91 A;  4PSS A;  1AI9 A;  1LUD A;  3RO9 A;  4KM0 A;  4KFJ A;  3K74 A;  1RX4 A;  2HQP A;  4KEB A;  4CD2 A;  3SAI A;  4XT8 A;  3NXR A;  1OHJ A;  1DG5 A;  4KNE A;  2W9G A;  5FDA A;  3IRO A;  2FZH A;  3FQC A;  3SQY X;  1IA3 A;  1RX9 A;  3FYV X;  2INQ A;  2G6V A;  3F0U X;  4KL9 A;  4X5G A;  3QL0 A;  1DYJ A;  3HBB A; 
#chains in the Genus database with same CATH topology
 3RG9 A;  2FZJ A;  1RA8 A;  1DR3 A;  3F0V X;  4M2X A;  4X5H A;  3QL3 A;  3QGT A;  4KD7 A;  3GYF A;  1RX1 A;  3S3V A;  4H98 A;  1DYI A;  2O7P A;  3F0B X;  4XE6 X;  4EIL A;  3NU0 A;  4P66 A;  3FRF X;  2GD9 A;  5E8Q A;  1RX7 A;  2DRC A;  1VJ3 A;  4KJJ A;  3CD2 A;  1DR5 A;  5DXV A;  4LAG X;  1AOE A;  3KY8 A;  5HF0 X;  3TQ9 A;  3SA2 A;  4EJ1 A;  1HFP A;  4PST A;  2ZZA A;  2HXV A;  1HFR A;  4TU5 X;  3SRW X;  4Q0E A;  1S3Y A;  8DFR A;  4OSG A;  3E0B A;  4IXF X;  3HJ3 A;  4P3Q A;  3K2H A;  3SR5 X;  4IXG X;  1DRF A;  4HOF A;  2ANO A;  3FQ0 A;  3QLX A;  2CIG A;  3NXT A;  4FHB A;  1J3K A;  4DFR A;  3EEL A;  2W9H A;  4G3M A;  4XT5 A;  3F0S X;  3QYL A;  2D0K A;  1J3I A;  1CD2 A;  3GHC A;  1KMV A;  1RX5 A;  1DR2 A;  1E26 A;  3DRC A;  5HI6 A;  6DFR A;  3EX8 A;  3CSE A;  4HA9 A;  5U26 A;  1IA1 A;  3IRM A;  1RA2 A;  4H97 A;  4QLE A;  1JOM A;  2FZI A;  5HT5 A;  3IA4 A;  3ROA A;  3KGY A;  3SRU X;  4PDJ A;  3NZC X;  2XW7 A;  1JUV A;  1RA1 A;  3I3R A;  3M08 A;  4P68 A;  3NZB X;  5HF2 X;  3IRN A;  1M7A A;  1TDR A;  3FQV A;  3TQA A;  2W3W A;  4KBN A;  3SH2 A;  3OAF A;  4H95 A;  5EAJ A;  3CL9 A;  3FRA X;  1M79 A;  4M6L A;  3DGA A;  5HQY A;  3F8Y A;  3KJS A;  4HOE A;  1DYR A;  3QYO A;  3EIG A;  1JOL A;  1RH3 A;  4ELG A;  4XRB A;  3ZPG A;  2C2S A;  5JG0 X;  4ELF A;  4ELH A;  1PDB A;  2W3V A;  3SGY A;  4KYA A;  1DLS A;  3SA1 A;  3Q1H A;  1RX3 A;  3FY9 X;  3FL8 A;  1RX6 A;  1RX8 A;  1DYH A;  3F0X X;  1LY4 A;  3K45 A;  3JWK A;  5HSR A;  4M6K A;  3CLB A;  2CD2 A;  4M7U A;  3QG2 A;  3NXX A;  4X5F A;  2W9T A;  4FGH A;  3FY8 X;  3K47 A;  3D80 A;  4PSY A;  2P4G A;  3TQB A;  4GH8 A;  1ZDR A;  1D1G A;  3OCH A;  3DL6 A;  2W3M A;  2W3B A;  1IA4 A;  4EIG A;  3QLS A;  3DAT A;  1RE7 A;  4FGG A;  3NXO A;  3N0H A;  3NRR A;  3FS6 A;  1AO8 A;  3FQZ A;  3R33 A;  5ECC A;  1RB2 A;  1U70 A;  1U72 A;  3DAU A;  3DL5 A;  4DDR A;  3KFY A;  4PTH A;  5HSU A;  1OHK A;  3FYW X;  3NXV A;  5U27 A;  2LF1 A;  1S3U A;  1DHF A;  3S7A A;  1QZF A;  7DFR A;  1DLR A;  4KJK A;  2BL9 A;  1RG7 A;  2C2T A;  4ELB A;  3KJR A;  1CZ3 A;  2OBC A;  4QLG A;  1YHO A;  3GI2 A;  1RC4 A;  2AZN A;  3GHW A;  4PTJ A;  3GHV A;  4RGC A;  1DG8 A;  1RA9 A;  4Q67 A;  1PD9 A;  3SRR X;  3DFR A;  4LAE X;  5DFR A;  1DRB A;  3ZPC A;  4I1N A;  3FRE X;  4KM2 A;  1LY3 A;  3I8A X;  1RA3 A;  4I13 A;  1DR7 A;  4QI9 A;  4KLX A;  4XT6 A;  2BLA A;  1DG7 A;  2B3Z A;  4G95 A;  2JYB A;  2H2Q A;  3SRS X;  2BLB A;  5CCC A;  4X5I A;  3F8Z A;  4ECK A;  2OIP A;  4H96 A;  1MVT A;  3NZ6 X;  3FQF A;  2BLC A;  2DHF A;  4NX6 A;  1DRH A;  2ANQ A;  1DHJ A;  4ELE A;  2QK8 A;  5HT4 A;  5HUI A;  1VDR A;  3JVX A;  4KAK A;  4XEC X;  4DPH A;  3JWM A;  3TD8 A;  4LAH X;  2HM9 A;  1KMS A;  3FQO A;  3INV A;  3JTW A;  1RB3 A;  3EEM A;  4DPD A;  1DRA A;  4KY8 A;  3JWC A;  4QJZ D;  1DR6 A;  1KLK A;  3EEK A;  3UM5 A;  3QLY A;  1DF7 A;  4XT7 A;  3JSU A;  4M6J A;  3DG8 A;  3D84 X;  1BOZ A;  3F0Q X;  5HQZ A;  4M7V A;  1M78 A;  3NZD A;  1DIU A;  1DIS A;  4QLF A;  5JA3 A;  5CC9 A;  1RX2 A;  3EEJ A;  4LEK X;  3QLW A;  1SEJ A;  4EIZ A;  2KGK A;  1HFQ A;  3IA5 A;  3FRD X;  1S3V A;  1U71 A;  3LG4 A;  3SRQ X;  1RD7 A;  4OR7 A;  1DRE A;  4P3R A;  1DR1 A;  3VCO A;  1DR4 A;  3FL9 A;  1J3J A;  3NZA X;  3FRB X;  3QLZ A;  3JW3 A;  4X5J A;  3UM6 A;  5HVE A;  5ECX A;  1DAJ A;  3UM8 A;  3NXY A;  4DP3 A;  3JW5 A;  4HA7 A;  4XT4 A;  1DDR A;  3QLR A;  3NTZ A;  3QFX A;  3TQ8 A;  3IX9 A;  2D5N A;  4Q0D A;  4HOG A;  2W9S A;  3JWF A;  3M09 A;  4KY4 A;  1MVS A;  4NX7 A;  4Q6A A;  1IA2 A;  4KJL A;  3NZ9 X;  1DHI A;  2ITH A;  2L28 A;  4QHV A;  4QJC A;  3S9U A;  1DDS A;  5HPB A;  1PD8 A;  3L3R A;  1S3W A;  4G8Z X;  2W3A A;  1BZF A;  4IXE D;  1RF7 A;  5HVB A;  3F91 A;  4PSS A;  1AI9 A;  1LUD A;  3RO9 A;  4KM0 A;  4KFJ A;  3K74 A;  1RX4 A;  2HQP A;  4KEB A;  4CD2 A;  3SAI A;  4XT8 A;  3NXR A;  1OHJ A;  1DG5 A;  4KNE A;  2W9G A;  5FDA A;  3IRO A;  2FZH A;  3FQC A;  3SQY X;  1IA3 A;  1RX9 A;  3FYV X;  2INQ A;  2G6V A;  3F0U X;  4KL9 A;  4X5G A;  3QL0 A;  1DYJ A;  3HBB A; 
#chains in the Genus database with same CATH homology
 3RG9 A;  2FZJ A;  1RA8 A;  1DR3 A;  3F0V X;  4M2X A;  4X5H A;  3QL3 A;  3QGT A;  4KD7 A;  3GYF A;  1RX1 A;  3S3V A;  4H98 A;  1DYI A;  2O7P A;  3F0B X;  4XE6 X;  4EIL A;  3NU0 A;  4P66 A;  3FRF X;  2GD9 A;  5E8Q A;  1RX7 A;  2DRC A;  1VJ3 A;  4KJJ A;  3CD2 A;  1DR5 A;  5DXV A;  4LAG X;  1AOE A;  3KY8 A;  5HF0 X;  3TQ9 A;  3SA2 A;  4EJ1 A;  1HFP A;  4PST A;  2ZZA A;  2HXV A;  1HFR A;  4TU5 X;  3SRW X;  4Q0E A;  1S3Y A;  8DFR A;  4OSG A;  3E0B A;  4IXF X;  3HJ3 A;  4P3Q A;  3K2H A;  3SR5 X;  4IXG X;  1DRF A;  4HOF A;  2ANO A;  3FQ0 A;  3QLX A;  2CIG A;  3NXT A;  4FHB A;  1J3K A;  4DFR A;  3EEL A;  2W9H A;  4G3M A;  4XT5 A;  3F0S X;  3QYL A;  2D0K A;  1J3I A;  1CD2 A;  3GHC A;  1KMV A;  1RX5 A;  1DR2 A;  1E26 A;  3DRC A;  5HI6 A;  6DFR A;  3EX8 A;  3CSE A;  4HA9 A;  5U26 A;  1IA1 A;  3IRM A;  1RA2 A;  4H97 A;  4QLE A;  1JOM A;  2FZI A;  5HT5 A;  3IA4 A;  3ROA A;  3KGY A;  3SRU X;  4PDJ A;  3NZC X;  2XW7 A;  1JUV A;  1RA1 A;  3I3R A;  3M08 A;  4P68 A;  3NZB X;  5HF2 X;  3IRN A;  1M7A A;  1TDR A;  3FQV A;  3TQA A;  2W3W A;  4KBN A;  3SH2 A;  3OAF A;  4H95 A;  5EAJ A;  3CL9 A;  3FRA X;  1M79 A;  4M6L A;  3DGA A;  5HQY A;  3F8Y A;  3KJS A;  4HOE A;  1DYR A;  3QYO A;  3EIG A;  1JOL A;  1RH3 A;  4ELG A;  4XRB A;  3ZPG A;  2C2S A;  5JG0 X;  4ELF A;  4ELH A;  1PDB A;  2W3V A;  3SGY A;  4KYA A;  1DLS A;  3SA1 A;  3Q1H A;  1RX3 A;  3FY9 X;  3FL8 A;  1RX6 A;  1RX8 A;  1DYH A;  3F0X X;  1LY4 A;  3K45 A;  3JWK A;  5HSR A;  4M6K A;  3CLB A;  2CD2 A;  4M7U A;  3QG2 A;  3NXX A;  4X5F A;  2W9T A;  4FGH A;  3FY8 X;  3K47 A;  3D80 A;  4PSY A;  2P4G A;  3TQB A;  4GH8 A;  1ZDR A;  1D1G A;  3OCH A;  3DL6 A;  2W3M A;  2W3B A;  1IA4 A;  4EIG A;  3QLS A;  3DAT A;  1RE7 A;  4FGG A;  3NXO A;  3N0H A;  3NRR A;  3FS6 A;  1AO8 A;  3FQZ A;  3R33 A;  5ECC A;  1RB2 A;  1U70 A;  1U72 A;  3DAU A;  3DL5 A;  4DDR A;  3KFY A;  4PTH A;  5HSU A;  1OHK A;  3FYW X;  3NXV A;  5U27 A;  2LF1 A;  1S3U A;  1DHF A;  3S7A A;  1QZF A;  7DFR A;  1DLR A;  4KJK A;  2BL9 A;  1RG7 A;  2C2T A;  4ELB A;  3KJR A;  1CZ3 A;  2OBC A;  4QLG A;  1YHO A;  3GI2 A;  1RC4 A;  2AZN A;  3GHW A;  4PTJ A;  3GHV A;  4RGC A;  1DG8 A;  1RA9 A;  4Q67 A;  1PD9 A;  3SRR X;  3DFR A;  4LAE X;  5DFR A;  1DRB A;  3ZPC A;  4I1N A;  3FRE X;  4KM2 A;  1LY3 A;  3I8A X;  1RA3 A;  4I13 A;  1DR7 A;  4QI9 A;  4KLX A;  4XT6 A;  2BLA A;  1DG7 A;  2B3Z A;  4G95 A;  2JYB A;  2H2Q A;  3SRS X;  2BLB A;  5CCC A;  4X5I A;  3F8Z A;  4ECK A;  2OIP A;  4H96 A;  1MVT A;  3NZ6 X;  3FQF A;  2BLC A;  2DHF A;  4NX6 A;  1DRH A;  2ANQ A;  1DHJ A;  4ELE A;  2QK8 A;  5HT4 A;  5HUI A;  1VDR A;  3JVX A;  4KAK A;  4XEC X;  4DPH A;  3JWM A;  3TD8 A;  4LAH X;  2HM9 A;  1KMS A;  3FQO A;  3INV A;  3JTW A;  1RB3 A;  3EEM A;  4DPD A;  1DRA A;  4KY8 A;  3JWC A;  4QJZ D;  1DR6 A;  1KLK A;  3EEK A;  3UM5 A;  3QLY A;  1DF7 A;  4XT7 A;  3JSU A;  4M6J A;  3DG8 A;  3D84 X;  1BOZ A;  3F0Q X;  5HQZ A;  4M7V A;  1M78 A;  3NZD A;  1DIU A;  1DIS A;  4QLF A;  5JA3 A;  5CC9 A;  1RX2 A;  3EEJ A;  4LEK X;  3QLW A;  1SEJ A;  4EIZ A;  2KGK A;  1HFQ A;  3IA5 A;  3FRD X;  1S3V A;  1U71 A;  3LG4 A;  3SRQ X;  1RD7 A;  4OR7 A;  1DRE A;  4P3R A;  1DR1 A;  3VCO A;  1DR4 A;  3FL9 A;  1J3J A;  3NZA X;  3FRB X;  3QLZ A;  3JW3 A;  4X5J A;  3UM6 A;  5HVE A;  5ECX A;  1DAJ A;  3UM8 A;  3NXY A;  4DP3 A;  3JW5 A;  4HA7 A;  4XT4 A;  1DDR A;  3QLR A;  3NTZ A;  3QFX A;  3TQ8 A;  3IX9 A;  2D5N A;  4Q0D A;  4HOG A;  2W9S A;  3JWF A;  3M09 A;  4KY4 A;  1MVS A;  4NX7 A;  4Q6A A;  1IA2 A;  4KJL A;  3NZ9 X;  1DHI A;  2ITH A;  2L28 A;  4QHV A;  4QJC A;  3S9U A;  1DDS A;  5HPB A;  1PD8 A;  3L3R A;  1S3W A;  4G8Z X;  2W3A A;  1BZF A;  4IXE D;  1RF7 A;  5HVB A;  3F91 A;  4PSS A;  1AI9 A;  1LUD A;  3RO9 A;  4KM0 A;  4KFJ A;  3K74 A;  1RX4 A;  2HQP A;  4KEB A;  4CD2 A;  3SAI A;  4XT8 A;  3NXR A;  1OHJ A;  1DG5 A;  4KNE A;  2W9G A;  5FDA A;  3IRO A;  2FZH A;  3FQC A;  3SQY X;  1IA3 A;  1RX9 A;  3FYV X;  2INQ A;  2G6V A;  3F0U X;  4KL9 A;  4X5G A;  3QL0 A;  1DYJ A;  3HBB A; 
2W9HA 3F0BX 3F0QX 3F0SX 3FQ0A 3FQCA 3FQZA 3FRDX 3FREX
similar chains in the Genus database (40% sequence similarity)
None
similar chains in the pdb database (40% sequence similarity)

 
#similar chains in the Genus database (40% sequence similarity)
2W9H A; 3F0B X; 3F0Q X; 3F0S X; 3FQ0 A; 3FQC A; 3FQZ A; 3FRD X; 3FRE X; 
#similar chains, but unknotted

#similar chains in the pdb database (40% sequence similarity)


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