3FRDX

S. aureus dhfr complexed with nadph and folate
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus
molecule keywords Dihydrofolate reductase
total genus 40
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3frdX00
5ECCA 3F0SX 2CD2A 3FQFA 5CCCA 3RG9A 3S9UA 1D1GA 3KJRA 4P68A 3VCOA 2HM9A 3SRQX 3QFXA 4KM0A 3FY9X 3IRNA 3DL5A 4KJKA 4HOGA 4EJ1A 4KD7A 1DHFA 1RX3A 4QHVA 3NZDA 3I8AX 4EIZA 1J3IA 1JOMA 1DAJA 4M7UA 3F0UX 4KBNA 4KJJA 4M2XA 1KLKA 1M78A 1J3KA 3GYFA 4QLGA 3SR5X 1VDRA 5HVBA 1RF7A 4FHBA 4PSTA 3TD8A 2P4GA 3FRDX 1DR3A 3F0BX 3D84X 1AOEA 2W9HA 1ZDRA 1S3YA 5HT5A 3FL8A 3M09A 4XRBA 7DFRA 3NRRA 1IA1A 3UM5A 1TDRA 3SRUX 3S3VA 2ITHA 1DYRA 1DRAA 1RH3A 3NZCX 1RX4A 3JTWA 1RB2A 3SA1A 3EEMA 1DYHA 2HQPA 2D0KA 2OIPA 4P3RA 2W9GA 4QI9A 4HA7A 4PSYA 3OCHA 3QLSA 2HXVA 1DYJA 1DG5A 4P3QA 3CD2A 4X5JA 3QL0A 3HJ3A 1RA8A 3JW3A 1DG7A 1DRBA 1RE7A 4LEKX 5HQYA 3Q1HA 3FQOA 1RX8A 4IXED 3ROAA 3TQ9A 1LY4A 3ZPCA 4HA9A 3F8YA 4GH8A 1S3WA 1S3UA 3GHCA 5JG0X 3K47A 4PSSA 3IX9A 3EEJA 5E8QA 4Q67A 4I13A 4EILA 4G8ZX 4XT5A 2AZNA 3K74A 3IA5A 3QLZA 4X5GA 4PTJA 4KY4A 5JA3A 4X5FA 3NXVA 4KM2A 2H2QA 1RX2A 5DFRA 3DL6A 4ELBA 3CL9A 4FGGA 2BLAA 2KGKA 2G6VA 2BL9A 3QYLA 2O7PA 1KMVA 3EELA 1M79A 1U70A 4QJZD 2FZHA 2ZZAA 3NZBX 1CD2A 4P66A 4ECKA 1LUDA 2OBCA 3QLRA 2W3VA 5HF0X 4G3MA 3F0VX 4NX6A 1S3VA 1BOZA 3SH2A 2W9SA 4I1NA 3FQCA 4EIGA 3QGTA 3QLWA 3F8ZA 1AO8A 5ECXA 1RA1A 3D80A 2DRCA 4M6KA 1DHJA 1RX5A 3N0HA 1DR2A 1OHJA 4X5HA 5EAJA 3FQVA 4ELHA 3FRBX 3SRWX 1PD8A 1U72A 1DHIA 4ELGA 3K45A 3JWKA 4M6LA 3NU0A 1DG8A 2W3MA 4H95A 3GHWA 3JWCA 3NXXA 3JW5A 1DRFA 3SRRX 1YHOA 1RX7A 4DDRA 1DR6A 1E26A 3INVA 1RA9A 2CIGA 3KJSA 1RX6A 4G95A 1RA2A 3NZAX 3KY8A 5U27A 4H98A 3JWMA 3SA2A 1KMSA 4QLEA 3IROA 3FRAX 4NX7A 1RB3A 3SGYA 4KAKA 8DFRA 5HQZA 4XT8A 1HFRA 1RX9A 2GD9A 3QG2A 1MVTA 2W9TA 1DLSA 3FL9A 1HFQA 3FRFX 2BLBA 3IRMA 3FY8X 3NXOA 3KGYA 3F0QX 3GHVA 5HUIA 4H96A 1SEJA 2W3WA 4DP3A 3DAUA 3FQ0A 3NXRA 3I3RA 1DF7A 1LY3A 1JUVA 3DGAA 4XT6A 4ELEA 1DYIA 1DR5A 3F91A 2W3AA 3TQAA 3CSEA 4Q0EA 4XECX 4Q0DA 3SQYX 1HFPA 1QZFA 4LAGX 3F0XX 1DR7A 3DG8A 4DFRA 4XT4A 3DRCA 1IA3A 3NXYA 4M7VA 4OR7A 4QJCA 2ANQA 5HSUA 4PTHA 1VJ3A 3FYWX 6DFRA 1DISA 3UM8A 3QYOA 5HT4A 3S7AA 4TU5X 3FQZA 2B3ZA 3TQBA 4KYAA 4RGCA 3ZPGA 5HSRA 4PDJA 3UM6A 1RX1A 3FYVX 2JYBA 4KJLA 2XW7A 2FZIA 1RA3A 2ANOA 3DATA 3EEKA 4LAHX 1DDRA 1U71A 3RO9A 5HVEA 4CD2A 5DXVA 2DHFA 1RD7A 1JOLA 3EX8A 3R33A 5U26A 3QLXA 3JWFA 4FGHA 3JVXA 4LAEX 4X5IA 3E0BA 3EIGA 1DIUA 3OAFA 3TQ8A 3JSUA 4KLXA 1CZ3A 2C2SA 2QK8A 3NTZA 3FS6A 1OHKA 4H97A 1DR4A 4KNEA 5HF2X 1MVSA 1RG7A 3GI2A 4M6JA 2FZJA 4IXGX 4XT7A 4KL9A 1DDSA 4DPDA 3NXTA 1DLRA 3LG4A 1DRHA 3KFYA 1PD9A 3CLBA 2BLCA 3FREX 3NZ9X 5HI6A 3SAIA 1J3JA 5HPBA 3SRSX 3L3RA 4KFJA 4HOEA 2L28A 2C2TA 4KY8A 4HOFA 2INQA 4QLFA 1BZFA 1IA2A 1RC4A 3M08A 2LF1A 1DREA 4IXFX 4ELFA 2W3BA 4OSGA 5FDAA 3HBBA 2D5NA 4XE6X 4DPHA 5CC9A 3K2HA 3DFRA 3NZ6X 1DR1A 3IA4A 1M7AA 4KEBA 3QLYA 1PDBA 1AI9A 1IA4A 4Q6AA 3QL3A
chains in the Genus database with same CATH superfamily
5ECCA 3F0SX 2CD2A 3FQFA 5CCCA 3RG9A 3S9UA 1D1GA 3KJRA 4P68A 3VCOA 2HM9A 3SRQX 3QFXA 4KM0A 3FY9X 3IRNA 3DL5A 4KJKA 4HOGA 4EJ1A 4KD7A 1DHFA 1RX3A 4QHVA 3NZDA 3I8AX 4EIZA 1J3IA 1JOMA 1DAJA 4M7UA 3F0UX 4KBNA 4KJJA 4M2XA 1KLKA 1M78A 1J3KA 3GYFA 4QLGA 3SR5X 1VDRA 5HVBA 1RF7A 4FHBA 4PSTA 3TD8A 2P4GA 3FRDX 1DR3A 3F0BX 3D84X 1AOEA 2W9HA 1ZDRA 1S3YA 5HT5A 3FL8A 3M09A 4XRBA 7DFRA 3NRRA 1IA1A 3UM5A 1TDRA 3SRUX 3S3VA 2ITHA 1DYRA 1DRAA 1RH3A 3NZCX 1RX4A 3JTWA 1RB2A 3SA1A 3EEMA 1DYHA 2HQPA 2D0KA 2OIPA 4P3RA 2W9GA 4QI9A 4HA7A 4PSYA 3OCHA 3QLSA 2HXVA 1DYJA 1DG5A 4P3QA 3CD2A 4X5JA 3QL0A 3HJ3A 1RA8A 3JW3A 1DG7A 1DRBA 1RE7A 4LEKX 5HQYA 3Q1HA 3FQOA 1RX8A 4IXED 3ROAA 3TQ9A 1LY4A 3ZPCA 4HA9A 3F8YA 4GH8A 1S3WA 1S3UA 3GHCA 5JG0X 3K47A 4PSSA 3IX9A 3EEJA 5E8QA 4Q67A 4I13A 4EILA 4G8ZX 4XT5A 2AZNA 3K74A 3IA5A 3QLZA 4X5GA 4PTJA 4KY4A 5JA3A 4X5FA 3NXVA 4KM2A 2H2QA 1RX2A 5DFRA 3DL6A 4ELBA 3CL9A 4FGGA 2BLAA 2KGKA 2G6VA 2BL9A 3QYLA 2O7PA 1KMVA 3EELA 1M79A 1U70A 4QJZD 2FZHA 2ZZAA 3NZBX 1CD2A 4P66A 4ECKA 1LUDA 2OBCA 3QLRA 2W3VA 5HF0X 4G3MA 3F0VX 4NX6A 1S3VA 1BOZA 3SH2A 2W9SA 4I1NA 3FQCA 4EIGA 3QGTA 3QLWA 3F8ZA 1AO8A 5ECXA 1RA1A 3D80A 2DRCA 4M6KA 1DHJA 1RX5A 3N0HA 1DR2A 1OHJA 4X5HA 5EAJA 3FQVA 4ELHA 3FRBX 3SRWX 1PD8A 1U72A 1DHIA 4ELGA 3K45A 3JWKA 4M6LA 3NU0A 1DG8A 2W3MA 4H95A 3GHWA 3JWCA 3NXXA 3JW5A 1DRFA 3SRRX 1YHOA 1RX7A 4DDRA 1DR6A 1E26A 3INVA 1RA9A 2CIGA 3KJSA 1RX6A 4G95A 1RA2A 3NZAX 3KY8A 5U27A 4H98A 3JWMA 3SA2A 1KMSA 4QLEA 3IROA 3FRAX 4NX7A 1RB3A 3SGYA 4KAKA 8DFRA 5HQZA 4XT8A 1HFRA 1RX9A 2GD9A 3QG2A 1MVTA 2W9TA 1DLSA 3FL9A 1HFQA 3FRFX 2BLBA 3IRMA 3FY8X 3NXOA 3KGYA 3F0QX 3GHVA 5HUIA 4H96A 1SEJA 2W3WA 4DP3A 3DAUA 3FQ0A 3NXRA 3I3RA 1DF7A 1LY3A 1JUVA 3DGAA 4XT6A 4ELEA 1DYIA 1DR5A 3F91A 2W3AA 3TQAA 3CSEA 4Q0EA 4XECX 4Q0DA 3SQYX 1HFPA 1QZFA 4LAGX 3F0XX 1DR7A 3DG8A 4DFRA 4XT4A 3DRCA 1IA3A 3NXYA 4M7VA 4OR7A 4QJCA 2ANQA 5HSUA 4PTHA 1VJ3A 3FYWX 6DFRA 1DISA 3UM8A 3QYOA 5HT4A 3S7AA 4TU5X 3FQZA 2B3ZA 3TQBA 4KYAA 4RGCA 3ZPGA 5HSRA 4PDJA 3UM6A 1RX1A 3FYVX 2JYBA 4KJLA 2XW7A 2FZIA 1RA3A 2ANOA 3DATA 3EEKA 4LAHX 1DDRA 1U71A 3RO9A 5HVEA 4CD2A 5DXVA 2DHFA 1RD7A 1JOLA 3EX8A 3R33A 5U26A 3QLXA 3JWFA 4FGHA 3JVXA 4LAEX 4X5IA 3E0BA 3EIGA 1DIUA 3OAFA 3TQ8A 3JSUA 4KLXA 1CZ3A 2C2SA 2QK8A 3NTZA 3FS6A 1OHKA 4H97A 1DR4A 4KNEA 5HF2X 1MVSA 1RG7A 3GI2A 4M6JA 2FZJA 4IXGX 4XT7A 4KL9A 1DDSA 4DPDA 3NXTA 1DLRA 3LG4A 1DRHA 3KFYA 1PD9A 3CLBA 2BLCA 3FREX 3NZ9X 5HI6A 3SAIA 1J3JA 5HPBA 3SRSX 3L3RA 4KFJA 4HOEA 2L28A 2C2TA 4KY8A 4HOFA 2INQA 4QLFA 1BZFA 1IA2A 1RC4A 3M08A 2LF1A 1DREA 4IXFX 4ELFA 2W3BA 4OSGA 5FDAA 3HBBA 2D5NA 4XE6X 4DPHA 5CC9A 3K2HA 3DFRA 3NZ6X 1DR1A 3IA4A 1M7AA 4KEBA 3QLYA 1PDBA 1AI9A 1IA4A 4Q6AA 3QL3A
chains in the Genus database with same CATH topology
5ECCA 3F0SX 2CD2A 3FQFA 5CCCA 3RG9A 3S9UA 1D1GA 3KJRA 4P68A 3VCOA 2HM9A 3SRQX 3QFXA 4KM0A 3FY9X 3IRNA 3DL5A 4KJKA 4HOGA 4EJ1A 4KD7A 1DHFA 1RX3A 4QHVA 3NZDA 3I8AX 4EIZA 1J3IA 1JOMA 1DAJA 4M7UA 3F0UX 4KBNA 4KJJA 4M2XA 1KLKA 1M78A 1J3KA 3GYFA 4QLGA 3SR5X 1VDRA 5HVBA 1RF7A 4FHBA 4PSTA 3TD8A 2P4GA 3FRDX 1DR3A 3F0BX 3D84X 1AOEA 2W9HA 1ZDRA 1S3YA 5HT5A 3FL8A 3M09A 4XRBA 7DFRA 3NRRA 1IA1A 3UM5A 1TDRA 3SRUX 3S3VA 2ITHA 1DYRA 1DRAA 1RH3A 3NZCX 1RX4A 3JTWA 1RB2A 3SA1A 3EEMA 1DYHA 2HQPA 2D0KA 2OIPA 4P3RA 2W9GA 4QI9A 4HA7A 4PSYA 3OCHA 3QLSA 2HXVA 1DYJA 1DG5A 4P3QA 3CD2A 4X5JA 3QL0A 3HJ3A 1RA8A 3JW3A 1DG7A 1DRBA 1RE7A 4LEKX 5HQYA 3Q1HA 3FQOA 1RX8A 4IXED 3ROAA 3TQ9A 1LY4A 3ZPCA 4HA9A 3F8YA 4GH8A 1S3WA 1S3UA 3GHCA 5JG0X 3K47A 4PSSA 3IX9A 3EEJA 5E8QA 4Q67A 4I13A 4EILA 4G8ZX 4XT5A 2AZNA 3K74A 3IA5A 3QLZA 4X5GA 4PTJA 4KY4A 5JA3A 4X5FA 3NXVA 4KM2A 2H2QA 1RX2A 5DFRA 3DL6A 4ELBA 3CL9A 4FGGA 2BLAA 2KGKA 2G6VA 2BL9A 3QYLA 2O7PA 1KMVA 3EELA 1M79A 1U70A 4QJZD 2FZHA 2ZZAA 3NZBX 1CD2A 4P66A 4ECKA 1LUDA 2OBCA 3QLRA 2W3VA 5HF0X 4G3MA 3F0VX 4NX6A 1S3VA 1BOZA 3SH2A 2W9SA 4I1NA 3FQCA 4EIGA 3QGTA 3QLWA 3F8ZA 1AO8A 5ECXA 1RA1A 3D80A 2DRCA 4M6KA 1DHJA 1RX5A 3N0HA 1DR2A 1OHJA 4X5HA 5EAJA 3FQVA 4ELHA 3FRBX 3SRWX 1PD8A 1U72A 1DHIA 4ELGA 3K45A 3JWKA 4M6LA 3NU0A 1DG8A 2W3MA 4H95A 3GHWA 3JWCA 3NXXA 3JW5A 1DRFA 3SRRX 1YHOA 1RX7A 4DDRA 1DR6A 1E26A 3INVA 1RA9A 2CIGA 3KJSA 1RX6A 4G95A 1RA2A 3NZAX 3KY8A 5U27A 4H98A 3JWMA 3SA2A 1KMSA 4QLEA 3IROA 3FRAX 4NX7A 1RB3A 3SGYA 4KAKA 8DFRA 5HQZA 4XT8A 1HFRA 1RX9A 2GD9A 3QG2A 1MVTA 2W9TA 1DLSA 3FL9A 1HFQA 3FRFX 2BLBA 3IRMA 3FY8X 3NXOA 3KGYA 3F0QX 3GHVA 5HUIA 4H96A 1SEJA 2W3WA 4DP3A 3DAUA 3FQ0A 3NXRA 3I3RA 1DF7A 1LY3A 1JUVA 3DGAA 4XT6A 4ELEA 1DYIA 1DR5A 3F91A 2W3AA 3TQAA 3CSEA 4Q0EA 4XECX 4Q0DA 3SQYX 1HFPA 1QZFA 4LAGX 3F0XX 1DR7A 3DG8A 4DFRA 4XT4A 3DRCA 1IA3A 3NXYA 4M7VA 4OR7A 4QJCA 2ANQA 5HSUA 4PTHA 1VJ3A 3FYWX 6DFRA 1DISA 3UM8A 3QYOA 5HT4A 3S7AA 4TU5X 3FQZA 2B3ZA 3TQBA 4KYAA 4RGCA 3ZPGA 5HSRA 4PDJA 3UM6A 1RX1A 3FYVX 2JYBA 4KJLA 2XW7A 2FZIA 1RA3A 2ANOA 3DATA 3EEKA 4LAHX 1DDRA 1U71A 3RO9A 5HVEA 4CD2A 5DXVA 2DHFA 1RD7A 1JOLA 3EX8A 3R33A 5U26A 3QLXA 3JWFA 4FGHA 3JVXA 4LAEX 4X5IA 3E0BA 3EIGA 1DIUA 3OAFA 3TQ8A 3JSUA 4KLXA 1CZ3A 2C2SA 2QK8A 3NTZA 3FS6A 1OHKA 4H97A 1DR4A 4KNEA 5HF2X 1MVSA 1RG7A 3GI2A 4M6JA 2FZJA 4IXGX 4XT7A 4KL9A 1DDSA 4DPDA 3NXTA 1DLRA 3LG4A 1DRHA 3KFYA 1PD9A 3CLBA 2BLCA 3FREX 3NZ9X 5HI6A 3SAIA 1J3JA 5HPBA 3SRSX 3L3RA 4KFJA 4HOEA 2L28A 2C2TA 4KY8A 4HOFA 2INQA 4QLFA 1BZFA 1IA2A 1RC4A 3M08A 2LF1A 1DREA 4IXFX 4ELFA 2W3BA 4OSGA 5FDAA 3HBBA 2D5NA 4XE6X 4DPHA 5CC9A 3K2HA 3DFRA 3NZ6X 1DR1A 3IA4A 1M7AA 4KEBA 3QLYA 1PDBA 1AI9A 1IA4A 4Q6AA 3QL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ECC A;  3F0S X;  2CD2 A;  3FQF A;  5CCC A;  3RG9 A;  3S9U A;  1D1G A;  3KJR A;  4P68 A;  3VCO A;  2HM9 A;  3SRQ X;  3QFX A;  4KM0 A;  3FY9 X;  3IRN A;  3DL5 A;  4KJK A;  4HOG A;  4EJ1 A;  4KD7 A;  1DHF A;  1RX3 A;  4QHV A;  3NZD A;  3I8A X;  4EIZ A;  1J3I A;  1JOM A;  1DAJ A;  4M7U A;  3F0U X;  4KBN A;  4KJJ A;  4M2X A;  1KLK A;  1M78 A;  1J3K A;  3GYF A;  4QLG A;  3SR5 X;  1VDR A;  5HVB A;  1RF7 A;  4FHB A;  4PST A;  3TD8 A;  2P4G A;  3FRD X;  1DR3 A;  3F0B X;  3D84 X;  1AOE A;  2W9H A;  1ZDR A;  1S3Y A;  5HT5 A;  3FL8 A;  3M09 A;  4XRB A;  7DFR A;  3NRR A;  1IA1 A;  3UM5 A;  1TDR A;  3SRU X;  3S3V A;  2ITH A;  1DYR A;  1DRA A;  1RH3 A;  3NZC X;  1RX4 A;  3JTW A;  1RB2 A;  3SA1 A;  3EEM A;  1DYH A;  2HQP A;  2D0K A;  2OIP A;  4P3R A;  2W9G A;  4QI9 A;  4HA7 A;  4PSY A;  3OCH A;  3QLS A;  2HXV A;  1DYJ A;  1DG5 A;  4P3Q A;  3CD2 A;  4X5J A;  3QL0 A;  3HJ3 A;  1RA8 A;  3JW3 A;  1DG7 A;  1DRB A;  1RE7 A;  4LEK X;  5HQY A;  3Q1H A;  3FQO A;  1RX8 A;  4IXE D;  3ROA A;  3TQ9 A;  1LY4 A;  3ZPC A;  4HA9 A;  3F8Y A;  4GH8 A;  1S3W A;  1S3U A;  3GHC A;  5JG0 X;  3K47 A;  4PSS A;  3IX9 A;  3EEJ A;  5E8Q A;  4Q67 A;  4I13 A;  4EIL A;  4G8Z X;  4XT5 A;  2AZN A;  3K74 A;  3IA5 A;  3QLZ A;  4X5G A;  4PTJ A;  4KY4 A;  5JA3 A;  4X5F A;  3NXV A;  4KM2 A;  2H2Q A;  1RX2 A;  5DFR A;  3DL6 A;  4ELB A;  3CL9 A;  4FGG A;  2BLA A;  2KGK A;  2G6V A;  2BL9 A;  3QYL A;  2O7P A;  1KMV A;  3EEL A;  1M79 A;  1U70 A;  4QJZ D;  2FZH A;  2ZZA A;  3NZB X;  1CD2 A;  4P66 A;  4ECK A;  1LUD A;  2OBC A;  3QLR A;  2W3V A;  5HF0 X;  4G3M A;  3F0V X;  4NX6 A;  1S3V A;  1BOZ A;  3SH2 A;  2W9S A;  4I1N A;  3FQC A;  4EIG A;  3QGT A;  3QLW A;  3F8Z A;  1AO8 A;  5ECX A;  1RA1 A;  3D80 A;  2DRC A;  4M6K A;  1DHJ A;  1RX5 A;  3N0H A;  1DR2 A;  1OHJ A;  4X5H A;  5EAJ A;  3FQV A;  4ELH A;  3FRB X;  3SRW X;  1PD8 A;  1U72 A;  1DHI A;  4ELG A;  3K45 A;  3JWK A;  4M6L A;  3NU0 A;  1DG8 A;  2W3M A;  4H95 A;  3GHW A;  3JWC A;  3NXX A;  3JW5 A;  1DRF A;  3SRR X;  1YHO A;  1RX7 A;  4DDR A;  1DR6 A;  1E26 A;  3INV A;  1RA9 A;  2CIG A;  3KJS A;  1RX6 A;  4G95 A;  1RA2 A;  3NZA X;  3KY8 A;  5U27 A;  4H98 A;  3JWM A;  3SA2 A;  1KMS A;  4QLE A;  3IRO A;  3FRA X;  4NX7 A;  1RB3 A;  3SGY A;  4KAK A;  8DFR A;  5HQZ A;  4XT8 A;  1HFR A;  1RX9 A;  2GD9 A;  3QG2 A;  1MVT A;  2W9T A;  1DLS A;  3FL9 A;  1HFQ A;  3FRF X;  2BLB A;  3IRM A;  3FY8 X;  3NXO A;  3KGY A;  3F0Q X;  3GHV A;  5HUI A;  4H96 A;  1SEJ A;  2W3W A;  4DP3 A;  3DAU A;  3FQ0 A;  3NXR A;  3I3R A;  1DF7 A;  1LY3 A;  1JUV A;  3DGA A;  4XT6 A;  4ELE A;  1DYI A;  1DR5 A;  3F91 A;  2W3A A;  3TQA A;  3CSE A;  4Q0E A;  4XEC X;  4Q0D A;  3SQY X;  1HFP A;  1QZF A;  4LAG X;  3F0X X;  1DR7 A;  3DG8 A;  4DFR A;  4XT4 A;  3DRC A;  1IA3 A;  3NXY A;  4M7V A;  4OR7 A;  4QJC A;  2ANQ A;  5HSU A;  4PTH A;  1VJ3 A;  3FYW X;  6DFR A;  1DIS A;  3UM8 A;  3QYO A;  5HT4 A;  3S7A A;  4TU5 X;  3FQZ A;  2B3Z A;  3TQB A;  4KYA A;  4RGC A;  3ZPG A;  5HSR A;  4PDJ A;  3UM6 A;  1RX1 A;  3FYV X;  2JYB A;  4KJL A;  2XW7 A;  2FZI A;  1RA3 A;  2ANO A;  3DAT A;  3EEK A;  4LAH X;  1DDR A;  1U71 A;  3RO9 A;  5HVE A;  4CD2 A;  5DXV A;  2DHF A;  1RD7 A;  1JOL A;  3EX8 A;  3R33 A;  5U26 A;  3QLX A;  3JWF A;  4FGH A;  3JVX A;  4LAE X;  4X5I A;  3E0B A;  3EIG A;  1DIU A;  3OAF A;  3TQ8 A;  3JSU A;  4KLX A;  1CZ3 A;  2C2S A;  2QK8 A;  3NTZ A;  3FS6 A;  1OHK A;  4H97 A;  1DR4 A;  4KNE A;  5HF2 X;  1MVS A;  1RG7 A;  3GI2 A;  4M6J A;  2FZJ A;  4IXG X;  4XT7 A;  4KL9 A;  1DDS A;  4DPD A;  3NXT A;  1DLR A;  3LG4 A;  1DRH A;  3KFY A;  1PD9 A;  3CLB A;  2BLC A;  3FRE X;  3NZ9 X;  5HI6 A;  3SAI A;  1J3J A;  5HPB A;  3SRS X;  3L3R A;  4KFJ A;  4HOE A;  2L28 A;  2C2T A;  4KY8 A;  4HOF A;  2INQ A;  4QLF A;  1BZF A;  1IA2 A;  1RC4 A;  3M08 A;  2LF1 A;  1DRE A;  4IXF X;  4ELF A;  2W3B A;  4OSG A;  5FDA A;  3HBB A;  2D5N A;  4XE6 X;  4DPH A;  5CC9 A;  3K2H A;  3DFR A;  3NZ6 X;  1DR1 A;  3IA4 A;  1M7A A;  4KEB A;  3QLY A;  1PDB A;  1AI9 A;  1IA4 A;  4Q6A A;  3QL3 A; 
#chains in the Genus database with same CATH topology
 5ECC A;  3F0S X;  2CD2 A;  3FQF A;  5CCC A;  3RG9 A;  3S9U A;  1D1G A;  3KJR A;  4P68 A;  3VCO A;  2HM9 A;  3SRQ X;  3QFX A;  4KM0 A;  3FY9 X;  3IRN A;  3DL5 A;  4KJK A;  4HOG A;  4EJ1 A;  4KD7 A;  1DHF A;  1RX3 A;  4QHV A;  3NZD A;  3I8A X;  4EIZ A;  1J3I A;  1JOM A;  1DAJ A;  4M7U A;  3F0U X;  4KBN A;  4KJJ A;  4M2X A;  1KLK A;  1M78 A;  1J3K A;  3GYF A;  4QLG A;  3SR5 X;  1VDR A;  5HVB A;  1RF7 A;  4FHB A;  4PST A;  3TD8 A;  2P4G A;  3FRD X;  1DR3 A;  3F0B X;  3D84 X;  1AOE A;  2W9H A;  1ZDR A;  1S3Y A;  5HT5 A;  3FL8 A;  3M09 A;  4XRB A;  7DFR A;  3NRR A;  1IA1 A;  3UM5 A;  1TDR A;  3SRU X;  3S3V A;  2ITH A;  1DYR A;  1DRA A;  1RH3 A;  3NZC X;  1RX4 A;  3JTW A;  1RB2 A;  3SA1 A;  3EEM A;  1DYH A;  2HQP A;  2D0K A;  2OIP A;  4P3R A;  2W9G A;  4QI9 A;  4HA7 A;  4PSY A;  3OCH A;  3QLS A;  2HXV A;  1DYJ A;  1DG5 A;  4P3Q A;  3CD2 A;  4X5J A;  3QL0 A;  3HJ3 A;  1RA8 A;  3JW3 A;  1DG7 A;  1DRB A;  1RE7 A;  4LEK X;  5HQY A;  3Q1H A;  3FQO A;  1RX8 A;  4IXE D;  3ROA A;  3TQ9 A;  1LY4 A;  3ZPC A;  4HA9 A;  3F8Y A;  4GH8 A;  1S3W A;  1S3U A;  3GHC A;  5JG0 X;  3K47 A;  4PSS A;  3IX9 A;  3EEJ A;  5E8Q A;  4Q67 A;  4I13 A;  4EIL A;  4G8Z X;  4XT5 A;  2AZN A;  3K74 A;  3IA5 A;  3QLZ A;  4X5G A;  4PTJ A;  4KY4 A;  5JA3 A;  4X5F A;  3NXV A;  4KM2 A;  2H2Q A;  1RX2 A;  5DFR A;  3DL6 A;  4ELB A;  3CL9 A;  4FGG A;  2BLA A;  2KGK A;  2G6V A;  2BL9 A;  3QYL A;  2O7P A;  1KMV A;  3EEL A;  1M79 A;  1U70 A;  4QJZ D;  2FZH A;  2ZZA A;  3NZB X;  1CD2 A;  4P66 A;  4ECK A;  1LUD A;  2OBC A;  3QLR A;  2W3V A;  5HF0 X;  4G3M A;  3F0V X;  4NX6 A;  1S3V A;  1BOZ A;  3SH2 A;  2W9S A;  4I1N A;  3FQC A;  4EIG A;  3QGT A;  3QLW A;  3F8Z A;  1AO8 A;  5ECX A;  1RA1 A;  3D80 A;  2DRC A;  4M6K A;  1DHJ A;  1RX5 A;  3N0H A;  1DR2 A;  1OHJ A;  4X5H A;  5EAJ A;  3FQV A;  4ELH A;  3FRB X;  3SRW X;  1PD8 A;  1U72 A;  1DHI A;  4ELG A;  3K45 A;  3JWK A;  4M6L A;  3NU0 A;  1DG8 A;  2W3M A;  4H95 A;  3GHW A;  3JWC A;  3NXX A;  3JW5 A;  1DRF A;  3SRR X;  1YHO A;  1RX7 A;  4DDR A;  1DR6 A;  1E26 A;  3INV A;  1RA9 A;  2CIG A;  3KJS A;  1RX6 A;  4G95 A;  1RA2 A;  3NZA X;  3KY8 A;  5U27 A;  4H98 A;  3JWM A;  3SA2 A;  1KMS A;  4QLE A;  3IRO A;  3FRA X;  4NX7 A;  1RB3 A;  3SGY A;  4KAK A;  8DFR A;  5HQZ A;  4XT8 A;  1HFR A;  1RX9 A;  2GD9 A;  3QG2 A;  1MVT A;  2W9T A;  1DLS A;  3FL9 A;  1HFQ A;  3FRF X;  2BLB A;  3IRM A;  3FY8 X;  3NXO A;  3KGY A;  3F0Q X;  3GHV A;  5HUI A;  4H96 A;  1SEJ A;  2W3W A;  4DP3 A;  3DAU A;  3FQ0 A;  3NXR A;  3I3R A;  1DF7 A;  1LY3 A;  1JUV A;  3DGA A;  4XT6 A;  4ELE A;  1DYI A;  1DR5 A;  3F91 A;  2W3A A;  3TQA A;  3CSE A;  4Q0E A;  4XEC X;  4Q0D A;  3SQY X;  1HFP A;  1QZF A;  4LAG X;  3F0X X;  1DR7 A;  3DG8 A;  4DFR A;  4XT4 A;  3DRC A;  1IA3 A;  3NXY A;  4M7V A;  4OR7 A;  4QJC A;  2ANQ A;  5HSU A;  4PTH A;  1VJ3 A;  3FYW X;  6DFR A;  1DIS A;  3UM8 A;  3QYO A;  5HT4 A;  3S7A A;  4TU5 X;  3FQZ A;  2B3Z A;  3TQB A;  4KYA A;  4RGC A;  3ZPG A;  5HSR A;  4PDJ A;  3UM6 A;  1RX1 A;  3FYV X;  2JYB A;  4KJL A;  2XW7 A;  2FZI A;  1RA3 A;  2ANO A;  3DAT A;  3EEK A;  4LAH X;  1DDR A;  1U71 A;  3RO9 A;  5HVE A;  4CD2 A;  5DXV A;  2DHF A;  1RD7 A;  1JOL A;  3EX8 A;  3R33 A;  5U26 A;  3QLX A;  3JWF A;  4FGH A;  3JVX A;  4LAE X;  4X5I A;  3E0B A;  3EIG A;  1DIU A;  3OAF A;  3TQ8 A;  3JSU A;  4KLX A;  1CZ3 A;  2C2S A;  2QK8 A;  3NTZ A;  3FS6 A;  1OHK A;  4H97 A;  1DR4 A;  4KNE A;  5HF2 X;  1MVS A;  1RG7 A;  3GI2 A;  4M6J A;  2FZJ A;  4IXG X;  4XT7 A;  4KL9 A;  1DDS A;  4DPD A;  3NXT A;  1DLR A;  3LG4 A;  1DRH A;  3KFY A;  1PD9 A;  3CLB A;  2BLC A;  3FRE X;  3NZ9 X;  5HI6 A;  3SAI A;  1J3J A;  5HPB A;  3SRS X;  3L3R A;  4KFJ A;  4HOE A;  2L28 A;  2C2T A;  4KY8 A;  4HOF A;  2INQ A;  4QLF A;  1BZF A;  1IA2 A;  1RC4 A;  3M08 A;  2LF1 A;  1DRE A;  4IXF X;  4ELF A;  2W3B A;  4OSG A;  5FDA A;  3HBB A;  2D5N A;  4XE6 X;  4DPH A;  5CC9 A;  3K2H A;  3DFR A;  3NZ6 X;  1DR1 A;  3IA4 A;  1M7A A;  4KEB A;  3QLY A;  1PDB A;  1AI9 A;  1IA4 A;  4Q6A A;  3QL3 A; 
#chains in the Genus database with same CATH homology
 5ECC A;  3F0S X;  2CD2 A;  3FQF A;  5CCC A;  3RG9 A;  3S9U A;  1D1G A;  3KJR A;  4P68 A;  3VCO A;  2HM9 A;  3SRQ X;  3QFX A;  4KM0 A;  3FY9 X;  3IRN A;  3DL5 A;  4KJK A;  4HOG A;  4EJ1 A;  4KD7 A;  1DHF A;  1RX3 A;  4QHV A;  3NZD A;  3I8A X;  4EIZ A;  1J3I A;  1JOM A;  1DAJ A;  4M7U A;  3F0U X;  4KBN A;  4KJJ A;  4M2X A;  1KLK A;  1M78 A;  1J3K A;  3GYF A;  4QLG A;  3SR5 X;  1VDR A;  5HVB A;  1RF7 A;  4FHB A;  4PST A;  3TD8 A;  2P4G A;  3FRD X;  1DR3 A;  3F0B X;  3D84 X;  1AOE A;  2W9H A;  1ZDR A;  1S3Y A;  5HT5 A;  3FL8 A;  3M09 A;  4XRB A;  7DFR A;  3NRR A;  1IA1 A;  3UM5 A;  1TDR A;  3SRU X;  3S3V A;  2ITH A;  1DYR A;  1DRA A;  1RH3 A;  3NZC X;  1RX4 A;  3JTW A;  1RB2 A;  3SA1 A;  3EEM A;  1DYH A;  2HQP A;  2D0K A;  2OIP A;  4P3R A;  2W9G A;  4QI9 A;  4HA7 A;  4PSY A;  3OCH A;  3QLS A;  2HXV A;  1DYJ A;  1DG5 A;  4P3Q A;  3CD2 A;  4X5J A;  3QL0 A;  3HJ3 A;  1RA8 A;  3JW3 A;  1DG7 A;  1DRB A;  1RE7 A;  4LEK X;  5HQY A;  3Q1H A;  3FQO A;  1RX8 A;  4IXE D;  3ROA A;  3TQ9 A;  1LY4 A;  3ZPC A;  4HA9 A;  3F8Y A;  4GH8 A;  1S3W A;  1S3U A;  3GHC A;  5JG0 X;  3K47 A;  4PSS A;  3IX9 A;  3EEJ A;  5E8Q A;  4Q67 A;  4I13 A;  4EIL A;  4G8Z X;  4XT5 A;  2AZN A;  3K74 A;  3IA5 A;  3QLZ A;  4X5G A;  4PTJ A;  4KY4 A;  5JA3 A;  4X5F A;  3NXV A;  4KM2 A;  2H2Q A;  1RX2 A;  5DFR A;  3DL6 A;  4ELB A;  3CL9 A;  4FGG A;  2BLA A;  2KGK A;  2G6V A;  2BL9 A;  3QYL A;  2O7P A;  1KMV A;  3EEL A;  1M79 A;  1U70 A;  4QJZ D;  2FZH A;  2ZZA A;  3NZB X;  1CD2 A;  4P66 A;  4ECK A;  1LUD A;  2OBC A;  3QLR A;  2W3V A;  5HF0 X;  4G3M A;  3F0V X;  4NX6 A;  1S3V A;  1BOZ A;  3SH2 A;  2W9S A;  4I1N A;  3FQC A;  4EIG A;  3QGT A;  3QLW A;  3F8Z A;  1AO8 A;  5ECX A;  1RA1 A;  3D80 A;  2DRC A;  4M6K A;  1DHJ A;  1RX5 A;  3N0H A;  1DR2 A;  1OHJ A;  4X5H A;  5EAJ A;  3FQV A;  4ELH A;  3FRB X;  3SRW X;  1PD8 A;  1U72 A;  1DHI A;  4ELG A;  3K45 A;  3JWK A;  4M6L A;  3NU0 A;  1DG8 A;  2W3M A;  4H95 A;  3GHW A;  3JWC A;  3NXX A;  3JW5 A;  1DRF A;  3SRR X;  1YHO A;  1RX7 A;  4DDR A;  1DR6 A;  1E26 A;  3INV A;  1RA9 A;  2CIG A;  3KJS A;  1RX6 A;  4G95 A;  1RA2 A;  3NZA X;  3KY8 A;  5U27 A;  4H98 A;  3JWM A;  3SA2 A;  1KMS A;  4QLE A;  3IRO A;  3FRA X;  4NX7 A;  1RB3 A;  3SGY A;  4KAK A;  8DFR A;  5HQZ A;  4XT8 A;  1HFR A;  1RX9 A;  2GD9 A;  3QG2 A;  1MVT A;  2W9T A;  1DLS A;  3FL9 A;  1HFQ A;  3FRF X;  2BLB A;  3IRM A;  3FY8 X;  3NXO A;  3KGY A;  3F0Q X;  3GHV A;  5HUI A;  4H96 A;  1SEJ A;  2W3W A;  4DP3 A;  3DAU A;  3FQ0 A;  3NXR A;  3I3R A;  1DF7 A;  1LY3 A;  1JUV A;  3DGA A;  4XT6 A;  4ELE A;  1DYI A;  1DR5 A;  3F91 A;  2W3A A;  3TQA A;  3CSE A;  4Q0E A;  4XEC X;  4Q0D A;  3SQY X;  1HFP A;  1QZF A;  4LAG X;  3F0X X;  1DR7 A;  3DG8 A;  4DFR A;  4XT4 A;  3DRC A;  1IA3 A;  3NXY A;  4M7V A;  4OR7 A;  4QJC A;  2ANQ A;  5HSU A;  4PTH A;  1VJ3 A;  3FYW X;  6DFR A;  1DIS A;  3UM8 A;  3QYO A;  5HT4 A;  3S7A A;  4TU5 X;  3FQZ A;  2B3Z A;  3TQB A;  4KYA A;  4RGC A;  3ZPG A;  5HSR A;  4PDJ A;  3UM6 A;  1RX1 A;  3FYV X;  2JYB A;  4KJL A;  2XW7 A;  2FZI A;  1RA3 A;  2ANO A;  3DAT A;  3EEK A;  4LAH X;  1DDR A;  1U71 A;  3RO9 A;  5HVE A;  4CD2 A;  5DXV A;  2DHF A;  1RD7 A;  1JOL A;  3EX8 A;  3R33 A;  5U26 A;  3QLX A;  3JWF A;  4FGH A;  3JVX A;  4LAE X;  4X5I A;  3E0B A;  3EIG A;  1DIU A;  3OAF A;  3TQ8 A;  3JSU A;  4KLX A;  1CZ3 A;  2C2S A;  2QK8 A;  3NTZ A;  3FS6 A;  1OHK A;  4H97 A;  1DR4 A;  4KNE A;  5HF2 X;  1MVS A;  1RG7 A;  3GI2 A;  4M6J A;  2FZJ A;  4IXG X;  4XT7 A;  4KL9 A;  1DDS A;  4DPD A;  3NXT A;  1DLR A;  3LG4 A;  1DRH A;  3KFY A;  1PD9 A;  3CLB A;  2BLC A;  3FRE X;  3NZ9 X;  5HI6 A;  3SAI A;  1J3J A;  5HPB A;  3SRS X;  3L3R A;  4KFJ A;  4HOE A;  2L28 A;  2C2T A;  4KY8 A;  4HOF A;  2INQ A;  4QLF A;  1BZF A;  1IA2 A;  1RC4 A;  3M08 A;  2LF1 A;  1DRE A;  4IXF X;  4ELF A;  2W3B A;  4OSG A;  5FDA A;  3HBB A;  2D5N A;  4XE6 X;  4DPH A;  5CC9 A;  3K2H A;  3DFR A;  3NZ6 X;  1DR1 A;  3IA4 A;  1M7A A;  4KEB A;  3QLY A;  1PDB A;  1AI9 A;  1IA4 A;  4Q6A A;  3QL3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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