3FS6A

Correlations of inhibitor kinetics for pneumocystis jirovecii and human dihydrofolate reductase with structural data for human active site mutant enzyme complexes
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Dihydrofolate reductase
total genus 54
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fs6A00
3QYLA 3FQCA 3I8AX 1DDRA 3KJRA 2CIGA 5JG0X 4HA9A 5HT4A 1BZFA 6DFRA 3SH2A 3NXYA 2OBCA 3D84X 3Q1HA 3NZBX 4EILA 1BOZA 4G3MA 3EIGA 3IX9A 4X5JA 4PSSA 3KFYA 3TD8A 5HSUA 5HVBA 1KMSA 4P68A 3JWFA 4ELFA 3TQ8A 1RH3A 3FS6A 4KL9A 4I13A 5DFRA 4XE6X 5HUIA 4KY4A 4M6JA 4IXFX 2ANQA 3QLWA 3QLXA 4LAGX 3FQOA 1RX9A 2W9GA 5CCCA 4M6KA 1J3IA 3GHCA 4HOGA 4KM2A 2FZHA 3EEJA 4QLFA 3CD2A 5E8QA 3QFXA 3OCHA 1CZ3A 4H98A 3GYFA 1M78A 3FQFA 1SEJA 1PD8A 3F0XX 3INVA 2INQA 5HI6A 1RX4A 3F0QX 2ITHA 1J3JA 3IA4A 1M7AA 4KJLA 1DG5A 4QI9A 1S3WA 1IA4A 4G8ZX 3UM6A 4XT5A 1LY3A 2BL9A 3NZ9X 4KLXA 3UM8A 3JW3A 1DR3A 2QK8A 4EIGA 3SRWX 5ECXA 1RX2A 1RC4A 3FL9A 2W3MA 4QJZD 3NTZA 3NXTA 2C2SA 3L3RA 1YHOA 4OR7A 2DRCA 4KJJA 3SGYA 4XT7A 1HFQA 1VJ3A 1D1GA 3SRQX 1AOEA 4QHVA 1OHJA 5JA3A 1S3VA 3IROA 3N0HA 3S9UA 4KD7A 1AI9A 5HPBA 4Q0EA 4H95A 1DG7A 3CL9A 3JSUA 3S3VA 4ECKA 3GI2A 3EEMA 4KEBA 3E0BA 3CLBA 3LG4A 4RGCA 1RA9A 5U26A 1DYHA 3QLZA 8DFRA 3FRFX 3JWMA 3K74A 1DR2A 4ELBA 3DRCA 4XT6A 3FQZA 4HOFA 4KY8A 4NX6A 3QLYA 4XT4A 3F0VX 1DRBA 5HT5A 4DP3A 1DR5A 5DXVA 4X5GA 4KAKA 3K47A 4QLEA 3HBBA 4XT8A 3DGAA 3NXXA 3S7AA 1RB3A 2W9HA 5HSRA 3FREX 3F8YA 4DDRA 2GD9A 3NZ6X 1DRFA 4KNEA 2BLBA 3KY8A 4XRBA 1CD2A 1DISA 3K2HA 1DDSA 4Q6AA 5HVEA 2H2QA 1RA3A 2D0KA 2BLCA 4KM0A 1DHFA 4H96A 4FGGA 3SQYX 3OAFA 3FRBX 4FGHA 2HQPA 3R33A 4DPDA 4ELGA 2W9TA 3EELA 3UM5A 1E26A 1S3UA 1PDBA 4KJKA 5ECCA 5EAJA 3GHWA 4CD2A 1ZDRA 4QLGA 1IA3A 4EJ1A 2B3ZA 1QZFA 4ELHA 4X5FA 2C2TA 3F8ZA 4Q0DA 5HQYA 3QGTA 1VDRA 4LAEX 3QYOA 3I3RA 3DFRA 3FQ0A 1DR7A 1JUVA 3IA5A 4M6LA 1RX7A 4ELEA 4IXGX 4DPHA 3HJ3A 4OSGA 3K45A 4QJCA 3SRRX 1RX5A 3DL6A 2JYBA 1RB2A 1HFPA 3ZPCA 1DR1A 1DAJA 3F0UX 3TQAA 4PSYA 1MVSA 1RX3A 2W3AA 5CC9A 3EX8A 3FY9X 3JWKA 3EEKA 3FL8A 1RA1A 2LF1A 1HFRA 4HA7A 3DG8A 1S3YA 1MVTA 3D80A 3DAUA 4H97A 3F91A 1RX8A 5FDAA 4NX7A 3NU0A 1RD7A 2AZNA 1JOMA 3M08A 1DF7A 3IRMA 1RE7A 2W3WA 3ROAA 4PTHA 2O7PA 2KGKA 4PSTA 2L28A 3QL3A 1DG8A 1IA2A 1TDRA 2D5NA 3SR5X 3SRSX 4I1NA 3M09A 1DRHA 2P4GA 4LEKX 4KBNA 4KYAA 2HM9A 4P3RA 3IRNA 1RA8A 1DLSA 3KJSA 1U70A 1U72A 3DATA 3NZCX 1U71A 3GHVA 2W9SA 4G95A 4EIZA 2W3VA 1M79A 3NZAX 1DHJA 1DREA 4PDJA 4P3QA 1DR6A 1KMVA 3NRRA 4M7UA 1DLRA 1DYRA 3FYWX 1RF7A 3QLSA 1AO8A 3QLRA 2G6VA 3FY8X 3JW5A 4X5HA 4HOEA 3TQ9A 5HF2X 1J3KA 2DHFA 3FYVX 1DYIA 4IXED 3RG9A 3KGYA 1DHIA 4P66A 3VCOA 1IA1A 3SA2A 4LAHX 3CSEA 4Q67A 2ZZAA 1PD9A 3F0BX 3NZDA 4X5IA 3FRAX 5U27A 2BLAA 4XECX 5HF0X 1DRAA 4PTJA 1JOLA 3JWCA 4GH8A 2FZJA 4TU5X 1OHKA 3TQBA 1DIUA 1DR4A 3NXRA 1LUDA 3FQVA 3QL0A 3NXOA 4KFJA 5HQZA 2XW7A 1RX6A 2HXVA 1LY4A 3SRUX 1RX1A 3F0SX 2CD2A 4DFRA 3SAIA 2OIPA 3NXVA 3ZPGA 3JVXA 1KLKA 4M2XA 4FHBA 2ANOA 7DFRA 2W3BA 2FZIA 4M7VA 3JTWA 3RO9A 1DYJA 1RA2A 3QG2A 3SA1A 3FRDX 3DL5A 1RG7A
chains in the Genus database with same CATH superfamily
3QYLA 3FQCA 3I8AX 1DDRA 3KJRA 2CIGA 5JG0X 4HA9A 5HT4A 1BZFA 6DFRA 3SH2A 3NXYA 2OBCA 3D84X 3Q1HA 3NZBX 4EILA 1BOZA 4G3MA 3EIGA 3IX9A 4X5JA 4PSSA 3KFYA 3TD8A 5HSUA 5HVBA 1KMSA 4P68A 3JWFA 4ELFA 3TQ8A 1RH3A 3FS6A 4KL9A 4I13A 5DFRA 4XE6X 5HUIA 4KY4A 4M6JA 4IXFX 2ANQA 3QLWA 3QLXA 4LAGX 3FQOA 1RX9A 2W9GA 5CCCA 4M6KA 1J3IA 3GHCA 4HOGA 4KM2A 2FZHA 3EEJA 4QLFA 3CD2A 5E8QA 3QFXA 3OCHA 1CZ3A 4H98A 3GYFA 1M78A 3FQFA 1SEJA 1PD8A 3F0XX 3INVA 2INQA 5HI6A 1RX4A 3F0QX 2ITHA 1J3JA 3IA4A 1M7AA 4KJLA 1DG5A 4QI9A 1S3WA 1IA4A 4G8ZX 3UM6A 4XT5A 1LY3A 2BL9A 3NZ9X 4KLXA 3UM8A 3JW3A 1DR3A 2QK8A 4EIGA 3SRWX 5ECXA 1RX2A 1RC4A 3FL9A 2W3MA 4QJZD 3NTZA 3NXTA 2C2SA 3L3RA 1YHOA 4OR7A 2DRCA 4KJJA 3SGYA 4XT7A 1HFQA 1VJ3A 1D1GA 3SRQX 1AOEA 4QHVA 1OHJA 5JA3A 1S3VA 3IROA 3N0HA 3S9UA 4KD7A 1AI9A 5HPBA 4Q0EA 4H95A 1DG7A 3CL9A 3JSUA 3S3VA 4ECKA 3GI2A 3EEMA 4KEBA 3E0BA 3CLBA 3LG4A 4RGCA 1RA9A 5U26A 1DYHA 3QLZA 8DFRA 3FRFX 3JWMA 3K74A 1DR2A 4ELBA 3DRCA 4XT6A 3FQZA 4HOFA 4KY8A 4NX6A 3QLYA 4XT4A 3F0VX 1DRBA 5HT5A 4DP3A 1DR5A 5DXVA 4X5GA 4KAKA 3K47A 4QLEA 3HBBA 4XT8A 3DGAA 3NXXA 3S7AA 1RB3A 2W9HA 5HSRA 3FREX 3F8YA 4DDRA 2GD9A 3NZ6X 1DRFA 4KNEA 2BLBA 3KY8A 4XRBA 1CD2A 1DISA 3K2HA 1DDSA 4Q6AA 5HVEA 2H2QA 1RA3A 2D0KA 2BLCA 4KM0A 1DHFA 4H96A 4FGGA 3SQYX 3OAFA 3FRBX 4FGHA 2HQPA 3R33A 4DPDA 4ELGA 2W9TA 3EELA 3UM5A 1E26A 1S3UA 1PDBA 4KJKA 5ECCA 5EAJA 3GHWA 4CD2A 1ZDRA 4QLGA 1IA3A 4EJ1A 2B3ZA 1QZFA 4ELHA 4X5FA 2C2TA 3F8ZA 4Q0DA 5HQYA 3QGTA 1VDRA 4LAEX 3QYOA 3I3RA 3DFRA 3FQ0A 1DR7A 1JUVA 3IA5A 4M6LA 1RX7A 4ELEA 4IXGX 4DPHA 3HJ3A 4OSGA 3K45A 4QJCA 3SRRX 1RX5A 3DL6A 2JYBA 1RB2A 1HFPA 3ZPCA 1DR1A 1DAJA 3F0UX 3TQAA 4PSYA 1MVSA 1RX3A 2W3AA 5CC9A 3EX8A 3FY9X 3JWKA 3EEKA 3FL8A 1RA1A 2LF1A 1HFRA 4HA7A 3DG8A 1S3YA 1MVTA 3D80A 3DAUA 4H97A 3F91A 1RX8A 5FDAA 4NX7A 3NU0A 1RD7A 2AZNA 1JOMA 3M08A 1DF7A 3IRMA 1RE7A 2W3WA 3ROAA 4PTHA 2O7PA 2KGKA 4PSTA 2L28A 3QL3A 1DG8A 1IA2A 1TDRA 2D5NA 3SR5X 3SRSX 4I1NA 3M09A 1DRHA 2P4GA 4LEKX 4KBNA 4KYAA 2HM9A 4P3RA 3IRNA 1RA8A 1DLSA 3KJSA 1U70A 1U72A 3DATA 3NZCX 1U71A 3GHVA 2W9SA 4G95A 4EIZA 2W3VA 1M79A 3NZAX 1DHJA 1DREA 4PDJA 4P3QA 1DR6A 1KMVA 3NRRA 4M7UA 1DLRA 1DYRA 3FYWX 1RF7A 3QLSA 1AO8A 3QLRA 2G6VA 3FY8X 3JW5A 4X5HA 4HOEA 3TQ9A 5HF2X 1J3KA 2DHFA 3FYVX 1DYIA 4IXED 3RG9A 3KGYA 1DHIA 4P66A 3VCOA 1IA1A 3SA2A 4LAHX 3CSEA 4Q67A 2ZZAA 1PD9A 3F0BX 3NZDA 4X5IA 3FRAX 5U27A 2BLAA 4XECX 5HF0X 1DRAA 4PTJA 1JOLA 3JWCA 4GH8A 2FZJA 4TU5X 1OHKA 3TQBA 1DIUA 1DR4A 3NXRA 1LUDA 3FQVA 3QL0A 3NXOA 4KFJA 5HQZA 2XW7A 1RX6A 2HXVA 1LY4A 3SRUX 1RX1A 3F0SX 2CD2A 4DFRA 3SAIA 2OIPA 3NXVA 3ZPGA 3JVXA 1KLKA 4M2XA 4FHBA 2ANOA 7DFRA 2W3BA 2FZIA 4M7VA 3JTWA 3RO9A 1DYJA 1RA2A 3QG2A 3SA1A 3FRDX 3DL5A 1RG7A
chains in the Genus database with same CATH topology
3QYLA 3FQCA 3I8AX 1DDRA 3KJRA 2CIGA 5JG0X 4HA9A 5HT4A 1BZFA 6DFRA 3SH2A 3NXYA 2OBCA 3D84X 3Q1HA 3NZBX 4EILA 1BOZA 4G3MA 3EIGA 3IX9A 4X5JA 4PSSA 3KFYA 3TD8A 5HSUA 5HVBA 1KMSA 4P68A 3JWFA 4ELFA 3TQ8A 1RH3A 3FS6A 4KL9A 4I13A 5DFRA 4XE6X 5HUIA 4KY4A 4M6JA 4IXFX 2ANQA 3QLWA 3QLXA 4LAGX 3FQOA 1RX9A 2W9GA 5CCCA 4M6KA 1J3IA 3GHCA 4HOGA 4KM2A 2FZHA 3EEJA 4QLFA 3CD2A 5E8QA 3QFXA 3OCHA 1CZ3A 4H98A 3GYFA 1M78A 3FQFA 1SEJA 1PD8A 3F0XX 3INVA 2INQA 5HI6A 1RX4A 3F0QX 2ITHA 1J3JA 3IA4A 1M7AA 4KJLA 1DG5A 4QI9A 1S3WA 1IA4A 4G8ZX 3UM6A 4XT5A 1LY3A 2BL9A 3NZ9X 4KLXA 3UM8A 3JW3A 1DR3A 2QK8A 4EIGA 3SRWX 5ECXA 1RX2A 1RC4A 3FL9A 2W3MA 4QJZD 3NTZA 3NXTA 2C2SA 3L3RA 1YHOA 4OR7A 2DRCA 4KJJA 3SGYA 4XT7A 1HFQA 1VJ3A 1D1GA 3SRQX 1AOEA 4QHVA 1OHJA 5JA3A 1S3VA 3IROA 3N0HA 3S9UA 4KD7A 1AI9A 5HPBA 4Q0EA 4H95A 1DG7A 3CL9A 3JSUA 3S3VA 4ECKA 3GI2A 3EEMA 4KEBA 3E0BA 3CLBA 3LG4A 4RGCA 1RA9A 5U26A 1DYHA 3QLZA 8DFRA 3FRFX 3JWMA 3K74A 1DR2A 4ELBA 3DRCA 4XT6A 3FQZA 4HOFA 4KY8A 4NX6A 3QLYA 4XT4A 3F0VX 1DRBA 5HT5A 4DP3A 1DR5A 5DXVA 4X5GA 4KAKA 3K47A 4QLEA 3HBBA 4XT8A 3DGAA 3NXXA 3S7AA 1RB3A 2W9HA 5HSRA 3FREX 3F8YA 4DDRA 2GD9A 3NZ6X 1DRFA 4KNEA 2BLBA 3KY8A 4XRBA 1CD2A 1DISA 3K2HA 1DDSA 4Q6AA 5HVEA 2H2QA 1RA3A 2D0KA 2BLCA 4KM0A 1DHFA 4H96A 4FGGA 3SQYX 3OAFA 3FRBX 4FGHA 2HQPA 3R33A 4DPDA 4ELGA 2W9TA 3EELA 3UM5A 1E26A 1S3UA 1PDBA 4KJKA 5ECCA 5EAJA 3GHWA 4CD2A 1ZDRA 4QLGA 1IA3A 4EJ1A 2B3ZA 1QZFA 4ELHA 4X5FA 2C2TA 3F8ZA 4Q0DA 5HQYA 3QGTA 1VDRA 4LAEX 3QYOA 3I3RA 3DFRA 3FQ0A 1DR7A 1JUVA 3IA5A 4M6LA 1RX7A 4ELEA 4IXGX 4DPHA 3HJ3A 4OSGA 3K45A 4QJCA 3SRRX 1RX5A 3DL6A 2JYBA 1RB2A 1HFPA 3ZPCA 1DR1A 1DAJA 3F0UX 3TQAA 4PSYA 1MVSA 1RX3A 2W3AA 5CC9A 3EX8A 3FY9X 3JWKA 3EEKA 3FL8A 1RA1A 2LF1A 1HFRA 4HA7A 3DG8A 1S3YA 1MVTA 3D80A 3DAUA 4H97A 3F91A 1RX8A 5FDAA 4NX7A 3NU0A 1RD7A 2AZNA 1JOMA 3M08A 1DF7A 3IRMA 1RE7A 2W3WA 3ROAA 4PTHA 2O7PA 2KGKA 4PSTA 2L28A 3QL3A 1DG8A 1IA2A 1TDRA 2D5NA 3SR5X 3SRSX 4I1NA 3M09A 1DRHA 2P4GA 4LEKX 4KBNA 4KYAA 2HM9A 4P3RA 3IRNA 1RA8A 1DLSA 3KJSA 1U70A 1U72A 3DATA 3NZCX 1U71A 3GHVA 2W9SA 4G95A 4EIZA 2W3VA 1M79A 3NZAX 1DHJA 1DREA 4PDJA 4P3QA 1DR6A 1KMVA 3NRRA 4M7UA 1DLRA 1DYRA 3FYWX 1RF7A 3QLSA 1AO8A 3QLRA 2G6VA 3FY8X 3JW5A 4X5HA 4HOEA 3TQ9A 5HF2X 1J3KA 2DHFA 3FYVX 1DYIA 4IXED 3RG9A 3KGYA 1DHIA 4P66A 3VCOA 1IA1A 3SA2A 4LAHX 3CSEA 4Q67A 2ZZAA 1PD9A 3F0BX 3NZDA 4X5IA 3FRAX 5U27A 2BLAA 4XECX 5HF0X 1DRAA 4PTJA 1JOLA 3JWCA 4GH8A 2FZJA 4TU5X 1OHKA 3TQBA 1DIUA 1DR4A 3NXRA 1LUDA 3FQVA 3QL0A 3NXOA 4KFJA 5HQZA 2XW7A 1RX6A 2HXVA 1LY4A 3SRUX 1RX1A 3F0SX 2CD2A 4DFRA 3SAIA 2OIPA 3NXVA 3ZPGA 3JVXA 1KLKA 4M2XA 4FHBA 2ANOA 7DFRA 2W3BA 2FZIA 4M7VA 3JTWA 3RO9A 1DYJA 1RA2A 3QG2A 3SA1A 3FRDX 3DL5A 1RG7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QYL A;  3FQC A;  3I8A X;  1DDR A;  3KJR A;  2CIG A;  5JG0 X;  4HA9 A;  5HT4 A;  1BZF A;  6DFR A;  3SH2 A;  3NXY A;  2OBC A;  3D84 X;  3Q1H A;  3NZB X;  4EIL A;  1BOZ A;  4G3M A;  3EIG A;  3IX9 A;  4X5J A;  4PSS A;  3KFY A;  3TD8 A;  5HSU A;  5HVB A;  1KMS A;  4P68 A;  3JWF A;  4ELF A;  3TQ8 A;  1RH3 A;  3FS6 A;  4KL9 A;  4I13 A;  5DFR A;  4XE6 X;  5HUI A;  4KY4 A;  4M6J A;  4IXF X;  2ANQ A;  3QLW A;  3QLX A;  4LAG X;  3FQO A;  1RX9 A;  2W9G A;  5CCC A;  4M6K A;  1J3I A;  3GHC A;  4HOG A;  4KM2 A;  2FZH A;  3EEJ A;  4QLF A;  3CD2 A;  5E8Q A;  3QFX A;  3OCH A;  1CZ3 A;  4H98 A;  3GYF A;  1M78 A;  3FQF A;  1SEJ A;  1PD8 A;  3F0X X;  3INV A;  2INQ A;  5HI6 A;  1RX4 A;  3F0Q X;  2ITH A;  1J3J A;  3IA4 A;  1M7A A;  4KJL A;  1DG5 A;  4QI9 A;  1S3W A;  1IA4 A;  4G8Z X;  3UM6 A;  4XT5 A;  1LY3 A;  2BL9 A;  3NZ9 X;  4KLX A;  3UM8 A;  3JW3 A;  1DR3 A;  2QK8 A;  4EIG A;  3SRW X;  5ECX A;  1RX2 A;  1RC4 A;  3FL9 A;  2W3M A;  4QJZ D;  3NTZ A;  3NXT A;  2C2S A;  3L3R A;  1YHO A;  4OR7 A;  2DRC A;  4KJJ A;  3SGY A;  4XT7 A;  1HFQ A;  1VJ3 A;  1D1G A;  3SRQ X;  1AOE A;  4QHV A;  1OHJ A;  5JA3 A;  1S3V A;  3IRO A;  3N0H A;  3S9U A;  4KD7 A;  1AI9 A;  5HPB A;  4Q0E A;  4H95 A;  1DG7 A;  3CL9 A;  3JSU A;  3S3V A;  4ECK A;  3GI2 A;  3EEM A;  4KEB A;  3E0B A;  3CLB A;  3LG4 A;  4RGC A;  1RA9 A;  5U26 A;  1DYH A;  3QLZ A;  8DFR A;  3FRF X;  3JWM A;  3K74 A;  1DR2 A;  4ELB A;  3DRC A;  4XT6 A;  3FQZ A;  4HOF A;  4KY8 A;  4NX6 A;  3QLY A;  4XT4 A;  3F0V X;  1DRB A;  5HT5 A;  4DP3 A;  1DR5 A;  5DXV A;  4X5G A;  4KAK A;  3K47 A;  4QLE A;  3HBB A;  4XT8 A;  3DGA A;  3NXX A;  3S7A A;  1RB3 A;  2W9H A;  5HSR A;  3FRE X;  3F8Y A;  4DDR A;  2GD9 A;  3NZ6 X;  1DRF A;  4KNE A;  2BLB A;  3KY8 A;  4XRB A;  1CD2 A;  1DIS A;  3K2H A;  1DDS A;  4Q6A A;  5HVE A;  2H2Q A;  1RA3 A;  2D0K A;  2BLC A;  4KM0 A;  1DHF A;  4H96 A;  4FGG A;  3SQY X;  3OAF A;  3FRB X;  4FGH A;  2HQP A;  3R33 A;  4DPD A;  4ELG A;  2W9T A;  3EEL A;  3UM5 A;  1E26 A;  1S3U A;  1PDB A;  4KJK A;  5ECC A;  5EAJ A;  3GHW A;  4CD2 A;  1ZDR A;  4QLG A;  1IA3 A;  4EJ1 A;  2B3Z A;  1QZF A;  4ELH A;  4X5F A;  2C2T A;  3F8Z A;  4Q0D A;  5HQY A;  3QGT A;  1VDR A;  4LAE X;  3QYO A;  3I3R A;  3DFR A;  3FQ0 A;  1DR7 A;  1JUV A;  3IA5 A;  4M6L A;  1RX7 A;  4ELE A;  4IXG X;  4DPH A;  3HJ3 A;  4OSG A;  3K45 A;  4QJC A;  3SRR X;  1RX5 A;  3DL6 A;  2JYB A;  1RB2 A;  1HFP A;  3ZPC A;  1DR1 A;  1DAJ A;  3F0U X;  3TQA A;  4PSY A;  1MVS A;  1RX3 A;  2W3A A;  5CC9 A;  3EX8 A;  3FY9 X;  3JWK A;  3EEK A;  3FL8 A;  1RA1 A;  2LF1 A;  1HFR A;  4HA7 A;  3DG8 A;  1S3Y A;  1MVT A;  3D80 A;  3DAU A;  4H97 A;  3F91 A;  1RX8 A;  5FDA A;  4NX7 A;  3NU0 A;  1RD7 A;  2AZN A;  1JOM A;  3M08 A;  1DF7 A;  3IRM A;  1RE7 A;  2W3W A;  3ROA A;  4PTH A;  2O7P A;  2KGK A;  4PST A;  2L28 A;  3QL3 A;  1DG8 A;  1IA2 A;  1TDR A;  2D5N A;  3SR5 X;  3SRS X;  4I1N A;  3M09 A;  1DRH A;  2P4G A;  4LEK X;  4KBN A;  4KYA A;  2HM9 A;  4P3R A;  3IRN A;  1RA8 A;  1DLS A;  3KJS A;  1U70 A;  1U72 A;  3DAT A;  3NZC X;  1U71 A;  3GHV A;  2W9S A;  4G95 A;  4EIZ A;  2W3V A;  1M79 A;  3NZA X;  1DHJ A;  1DRE A;  4PDJ A;  4P3Q A;  1DR6 A;  1KMV A;  3NRR A;  4M7U A;  1DLR A;  1DYR A;  3FYW X;  1RF7 A;  3QLS A;  1AO8 A;  3QLR A;  2G6V A;  3FY8 X;  3JW5 A;  4X5H A;  4HOE A;  3TQ9 A;  5HF2 X;  1J3K A;  2DHF A;  3FYV X;  1DYI A;  4IXE D;  3RG9 A;  3KGY A;  1DHI A;  4P66 A;  3VCO A;  1IA1 A;  3SA2 A;  4LAH X;  3CSE A;  4Q67 A;  2ZZA A;  1PD9 A;  3F0B X;  3NZD A;  4X5I A;  3FRA X;  5U27 A;  2BLA A;  4XEC X;  5HF0 X;  1DRA A;  4PTJ A;  1JOL A;  3JWC A;  4GH8 A;  2FZJ A;  4TU5 X;  1OHK A;  3TQB A;  1DIU A;  1DR4 A;  3NXR A;  1LUD A;  3FQV A;  3QL0 A;  3NXO A;  4KFJ A;  5HQZ A;  2XW7 A;  1RX6 A;  2HXV A;  1LY4 A;  3SRU X;  1RX1 A;  3F0S X;  2CD2 A;  4DFR A;  3SAI A;  2OIP A;  3NXV A;  3ZPG A;  3JVX A;  1KLK A;  4M2X A;  4FHB A;  2ANO A;  7DFR A;  2W3B A;  2FZI A;  4M7V A;  3JTW A;  3RO9 A;  1DYJ A;  1RA2 A;  3QG2 A;  3SA1 A;  3FRD X;  3DL5 A;  1RG7 A; 
#chains in the Genus database with same CATH topology
 3QYL A;  3FQC A;  3I8A X;  1DDR A;  3KJR A;  2CIG A;  5JG0 X;  4HA9 A;  5HT4 A;  1BZF A;  6DFR A;  3SH2 A;  3NXY A;  2OBC A;  3D84 X;  3Q1H A;  3NZB X;  4EIL A;  1BOZ A;  4G3M A;  3EIG A;  3IX9 A;  4X5J A;  4PSS A;  3KFY A;  3TD8 A;  5HSU A;  5HVB A;  1KMS A;  4P68 A;  3JWF A;  4ELF A;  3TQ8 A;  1RH3 A;  3FS6 A;  4KL9 A;  4I13 A;  5DFR A;  4XE6 X;  5HUI A;  4KY4 A;  4M6J A;  4IXF X;  2ANQ A;  3QLW A;  3QLX A;  4LAG X;  3FQO A;  1RX9 A;  2W9G A;  5CCC A;  4M6K A;  1J3I A;  3GHC A;  4HOG A;  4KM2 A;  2FZH A;  3EEJ A;  4QLF A;  3CD2 A;  5E8Q A;  3QFX A;  3OCH A;  1CZ3 A;  4H98 A;  3GYF A;  1M78 A;  3FQF A;  1SEJ A;  1PD8 A;  3F0X X;  3INV A;  2INQ A;  5HI6 A;  1RX4 A;  3F0Q X;  2ITH A;  1J3J A;  3IA4 A;  1M7A A;  4KJL A;  1DG5 A;  4QI9 A;  1S3W A;  1IA4 A;  4G8Z X;  3UM6 A;  4XT5 A;  1LY3 A;  2BL9 A;  3NZ9 X;  4KLX A;  3UM8 A;  3JW3 A;  1DR3 A;  2QK8 A;  4EIG A;  3SRW X;  5ECX A;  1RX2 A;  1RC4 A;  3FL9 A;  2W3M A;  4QJZ D;  3NTZ A;  3NXT A;  2C2S A;  3L3R A;  1YHO A;  4OR7 A;  2DRC A;  4KJJ A;  3SGY A;  4XT7 A;  1HFQ A;  1VJ3 A;  1D1G A;  3SRQ X;  1AOE A;  4QHV A;  1OHJ A;  5JA3 A;  1S3V A;  3IRO A;  3N0H A;  3S9U A;  4KD7 A;  1AI9 A;  5HPB A;  4Q0E A;  4H95 A;  1DG7 A;  3CL9 A;  3JSU A;  3S3V A;  4ECK A;  3GI2 A;  3EEM A;  4KEB A;  3E0B A;  3CLB A;  3LG4 A;  4RGC A;  1RA9 A;  5U26 A;  1DYH A;  3QLZ A;  8DFR A;  3FRF X;  3JWM A;  3K74 A;  1DR2 A;  4ELB A;  3DRC A;  4XT6 A;  3FQZ A;  4HOF A;  4KY8 A;  4NX6 A;  3QLY A;  4XT4 A;  3F0V X;  1DRB A;  5HT5 A;  4DP3 A;  1DR5 A;  5DXV A;  4X5G A;  4KAK A;  3K47 A;  4QLE A;  3HBB A;  4XT8 A;  3DGA A;  3NXX A;  3S7A A;  1RB3 A;  2W9H A;  5HSR A;  3FRE X;  3F8Y A;  4DDR A;  2GD9 A;  3NZ6 X;  1DRF A;  4KNE A;  2BLB A;  3KY8 A;  4XRB A;  1CD2 A;  1DIS A;  3K2H A;  1DDS A;  4Q6A A;  5HVE A;  2H2Q A;  1RA3 A;  2D0K A;  2BLC A;  4KM0 A;  1DHF A;  4H96 A;  4FGG A;  3SQY X;  3OAF A;  3FRB X;  4FGH A;  2HQP A;  3R33 A;  4DPD A;  4ELG A;  2W9T A;  3EEL A;  3UM5 A;  1E26 A;  1S3U A;  1PDB A;  4KJK A;  5ECC A;  5EAJ A;  3GHW A;  4CD2 A;  1ZDR A;  4QLG A;  1IA3 A;  4EJ1 A;  2B3Z A;  1QZF A;  4ELH A;  4X5F A;  2C2T A;  3F8Z A;  4Q0D A;  5HQY A;  3QGT A;  1VDR A;  4LAE X;  3QYO A;  3I3R A;  3DFR A;  3FQ0 A;  1DR7 A;  1JUV A;  3IA5 A;  4M6L A;  1RX7 A;  4ELE A;  4IXG X;  4DPH A;  3HJ3 A;  4OSG A;  3K45 A;  4QJC A;  3SRR X;  1RX5 A;  3DL6 A;  2JYB A;  1RB2 A;  1HFP A;  3ZPC A;  1DR1 A;  1DAJ A;  3F0U X;  3TQA A;  4PSY A;  1MVS A;  1RX3 A;  2W3A A;  5CC9 A;  3EX8 A;  3FY9 X;  3JWK A;  3EEK A;  3FL8 A;  1RA1 A;  2LF1 A;  1HFR A;  4HA7 A;  3DG8 A;  1S3Y A;  1MVT A;  3D80 A;  3DAU A;  4H97 A;  3F91 A;  1RX8 A;  5FDA A;  4NX7 A;  3NU0 A;  1RD7 A;  2AZN A;  1JOM A;  3M08 A;  1DF7 A;  3IRM A;  1RE7 A;  2W3W A;  3ROA A;  4PTH A;  2O7P A;  2KGK A;  4PST A;  2L28 A;  3QL3 A;  1DG8 A;  1IA2 A;  1TDR A;  2D5N A;  3SR5 X;  3SRS X;  4I1N A;  3M09 A;  1DRH A;  2P4G A;  4LEK X;  4KBN A;  4KYA A;  2HM9 A;  4P3R A;  3IRN A;  1RA8 A;  1DLS A;  3KJS A;  1U70 A;  1U72 A;  3DAT A;  3NZC X;  1U71 A;  3GHV A;  2W9S A;  4G95 A;  4EIZ A;  2W3V A;  1M79 A;  3NZA X;  1DHJ A;  1DRE A;  4PDJ A;  4P3Q A;  1DR6 A;  1KMV A;  3NRR A;  4M7U A;  1DLR A;  1DYR A;  3FYW X;  1RF7 A;  3QLS A;  1AO8 A;  3QLR A;  2G6V A;  3FY8 X;  3JW5 A;  4X5H A;  4HOE A;  3TQ9 A;  5HF2 X;  1J3K A;  2DHF A;  3FYV X;  1DYI A;  4IXE D;  3RG9 A;  3KGY A;  1DHI A;  4P66 A;  3VCO A;  1IA1 A;  3SA2 A;  4LAH X;  3CSE A;  4Q67 A;  2ZZA A;  1PD9 A;  3F0B X;  3NZD A;  4X5I A;  3FRA X;  5U27 A;  2BLA A;  4XEC X;  5HF0 X;  1DRA A;  4PTJ A;  1JOL A;  3JWC A;  4GH8 A;  2FZJ A;  4TU5 X;  1OHK A;  3TQB A;  1DIU A;  1DR4 A;  3NXR A;  1LUD A;  3FQV A;  3QL0 A;  3NXO A;  4KFJ A;  5HQZ A;  2XW7 A;  1RX6 A;  2HXV A;  1LY4 A;  3SRU X;  1RX1 A;  3F0S X;  2CD2 A;  4DFR A;  3SAI A;  2OIP A;  3NXV A;  3ZPG A;  3JVX A;  1KLK A;  4M2X A;  4FHB A;  2ANO A;  7DFR A;  2W3B A;  2FZI A;  4M7V A;  3JTW A;  3RO9 A;  1DYJ A;  1RA2 A;  3QG2 A;  3SA1 A;  3FRD X;  3DL5 A;  1RG7 A; 
#chains in the Genus database with same CATH homology
 3QYL A;  3FQC A;  3I8A X;  1DDR A;  3KJR A;  2CIG A;  5JG0 X;  4HA9 A;  5HT4 A;  1BZF A;  6DFR A;  3SH2 A;  3NXY A;  2OBC A;  3D84 X;  3Q1H A;  3NZB X;  4EIL A;  1BOZ A;  4G3M A;  3EIG A;  3IX9 A;  4X5J A;  4PSS A;  3KFY A;  3TD8 A;  5HSU A;  5HVB A;  1KMS A;  4P68 A;  3JWF A;  4ELF A;  3TQ8 A;  1RH3 A;  3FS6 A;  4KL9 A;  4I13 A;  5DFR A;  4XE6 X;  5HUI A;  4KY4 A;  4M6J A;  4IXF X;  2ANQ A;  3QLW A;  3QLX A;  4LAG X;  3FQO A;  1RX9 A;  2W9G A;  5CCC A;  4M6K A;  1J3I A;  3GHC A;  4HOG A;  4KM2 A;  2FZH A;  3EEJ A;  4QLF A;  3CD2 A;  5E8Q A;  3QFX A;  3OCH A;  1CZ3 A;  4H98 A;  3GYF A;  1M78 A;  3FQF A;  1SEJ A;  1PD8 A;  3F0X X;  3INV A;  2INQ A;  5HI6 A;  1RX4 A;  3F0Q X;  2ITH A;  1J3J A;  3IA4 A;  1M7A A;  4KJL A;  1DG5 A;  4QI9 A;  1S3W A;  1IA4 A;  4G8Z X;  3UM6 A;  4XT5 A;  1LY3 A;  2BL9 A;  3NZ9 X;  4KLX A;  3UM8 A;  3JW3 A;  1DR3 A;  2QK8 A;  4EIG A;  3SRW X;  5ECX A;  1RX2 A;  1RC4 A;  3FL9 A;  2W3M A;  4QJZ D;  3NTZ A;  3NXT A;  2C2S A;  3L3R A;  1YHO A;  4OR7 A;  2DRC A;  4KJJ A;  3SGY A;  4XT7 A;  1HFQ A;  1VJ3 A;  1D1G A;  3SRQ X;  1AOE A;  4QHV A;  1OHJ A;  5JA3 A;  1S3V A;  3IRO A;  3N0H A;  3S9U A;  4KD7 A;  1AI9 A;  5HPB A;  4Q0E A;  4H95 A;  1DG7 A;  3CL9 A;  3JSU A;  3S3V A;  4ECK A;  3GI2 A;  3EEM A;  4KEB A;  3E0B A;  3CLB A;  3LG4 A;  4RGC A;  1RA9 A;  5U26 A;  1DYH A;  3QLZ A;  8DFR A;  3FRF X;  3JWM A;  3K74 A;  1DR2 A;  4ELB A;  3DRC A;  4XT6 A;  3FQZ A;  4HOF A;  4KY8 A;  4NX6 A;  3QLY A;  4XT4 A;  3F0V X;  1DRB A;  5HT5 A;  4DP3 A;  1DR5 A;  5DXV A;  4X5G A;  4KAK A;  3K47 A;  4QLE A;  3HBB A;  4XT8 A;  3DGA A;  3NXX A;  3S7A A;  1RB3 A;  2W9H A;  5HSR A;  3FRE X;  3F8Y A;  4DDR A;  2GD9 A;  3NZ6 X;  1DRF A;  4KNE A;  2BLB A;  3KY8 A;  4XRB A;  1CD2 A;  1DIS A;  3K2H A;  1DDS A;  4Q6A A;  5HVE A;  2H2Q A;  1RA3 A;  2D0K A;  2BLC A;  4KM0 A;  1DHF A;  4H96 A;  4FGG A;  3SQY X;  3OAF A;  3FRB X;  4FGH A;  2HQP A;  3R33 A;  4DPD A;  4ELG A;  2W9T A;  3EEL A;  3UM5 A;  1E26 A;  1S3U A;  1PDB A;  4KJK A;  5ECC A;  5EAJ A;  3GHW A;  4CD2 A;  1ZDR A;  4QLG A;  1IA3 A;  4EJ1 A;  2B3Z A;  1QZF A;  4ELH A;  4X5F A;  2C2T A;  3F8Z A;  4Q0D A;  5HQY A;  3QGT A;  1VDR A;  4LAE X;  3QYO A;  3I3R A;  3DFR A;  3FQ0 A;  1DR7 A;  1JUV A;  3IA5 A;  4M6L A;  1RX7 A;  4ELE A;  4IXG X;  4DPH A;  3HJ3 A;  4OSG A;  3K45 A;  4QJC A;  3SRR X;  1RX5 A;  3DL6 A;  2JYB A;  1RB2 A;  1HFP A;  3ZPC A;  1DR1 A;  1DAJ A;  3F0U X;  3TQA A;  4PSY A;  1MVS A;  1RX3 A;  2W3A A;  5CC9 A;  3EX8 A;  3FY9 X;  3JWK A;  3EEK A;  3FL8 A;  1RA1 A;  2LF1 A;  1HFR A;  4HA7 A;  3DG8 A;  1S3Y A;  1MVT A;  3D80 A;  3DAU A;  4H97 A;  3F91 A;  1RX8 A;  5FDA A;  4NX7 A;  3NU0 A;  1RD7 A;  2AZN A;  1JOM A;  3M08 A;  1DF7 A;  3IRM A;  1RE7 A;  2W3W A;  3ROA A;  4PTH A;  2O7P A;  2KGK A;  4PST A;  2L28 A;  3QL3 A;  1DG8 A;  1IA2 A;  1TDR A;  2D5N A;  3SR5 X;  3SRS X;  4I1N A;  3M09 A;  1DRH A;  2P4G A;  4LEK X;  4KBN A;  4KYA A;  2HM9 A;  4P3R A;  3IRN A;  1RA8 A;  1DLS A;  3KJS A;  1U70 A;  1U72 A;  3DAT A;  3NZC X;  1U71 A;  3GHV A;  2W9S A;  4G95 A;  4EIZ A;  2W3V A;  1M79 A;  3NZA X;  1DHJ A;  1DRE A;  4PDJ A;  4P3Q A;  1DR6 A;  1KMV A;  3NRR A;  4M7U A;  1DLR A;  1DYR A;  3FYW X;  1RF7 A;  3QLS A;  1AO8 A;  3QLR A;  2G6V A;  3FY8 X;  3JW5 A;  4X5H A;  4HOE A;  3TQ9 A;  5HF2 X;  1J3K A;  2DHF A;  3FYV X;  1DYI A;  4IXE D;  3RG9 A;  3KGY A;  1DHI A;  4P66 A;  3VCO A;  1IA1 A;  3SA2 A;  4LAH X;  3CSE A;  4Q67 A;  2ZZA A;  1PD9 A;  3F0B X;  3NZD A;  4X5I A;  3FRA X;  5U27 A;  2BLA A;  4XEC X;  5HF0 X;  1DRA A;  4PTJ A;  1JOL A;  3JWC A;  4GH8 A;  2FZJ A;  4TU5 X;  1OHK A;  3TQB A;  1DIU A;  1DR4 A;  3NXR A;  1LUD A;  3FQV A;  3QL0 A;  3NXO A;  4KFJ A;  5HQZ A;  2XW7 A;  1RX6 A;  2HXV A;  1LY4 A;  3SRU X;  1RX1 A;  3F0S X;  2CD2 A;  4DFR A;  3SAI A;  2OIP A;  3NXV A;  3ZPG A;  3JVX A;  1KLK A;  4M2X A;  4FHB A;  2ANO A;  7DFR A;  2W3B A;  2FZI A;  4M7V A;  3JTW A;  3RO9 A;  1DYJ A;  1RA2 A;  3QG2 A;  3SA1 A;  3FRD X;  3DL5 A;  1RG7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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