3I8AX

Staphylococcus aureus h30n, f98y dihydrofolate reductase complexed with nadph and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (ucp120b)
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKNVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Staphylococcus aureus
publication title Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3i8aX00
1S3YA 3FRDX 1RX1A 3RG9A 2ANQA 3FYVX 4FGHA 3DRCA 3QYLA 3NXRA 3DFRA 1DAJA 2W3VA 3IX9A 1KMSA 3QLRA 3OAFA 4X5FA 1E26A 3QL3A 1CZ3A 3NU0A 3DATA 4ELHA 3SH2A 1RH3A 4HOFA 1M79A 4IXFX 2CD2A 3IRMA 2BLAA 3NXXA 3Q1HA 1DHIA 5ECCA 3KFYA 3TQ8A 1DRBA 3NXTA 3FRFX 4P3RA 1ZDRA 1M7AA 3F0BX 4KLXA 1KMVA 3IA4A 3K74A 1DG7A 3NZBX 3KJSA 4P68A 1RD7A 1RX6A 4H96A 1IA3A 3TQ9A 1RC4A 4H97A 4KFJA 4HOGA 3JWKA 1DRFA 4GH8A 4M2XA 4KD7A 3GHWA 4I1NA 3NZAX 3DG8A 4KJJA 4EJ1A 4OR7A 3SA2A 3SQYX 3F8ZA 2W3BA 2D0KA 3EIGA 3NXOA 4Q0EA 4ELBA 3FQCA 5HF0X 4KAKA 4KM2A 4KY4A 1U71A 2BLCA 3KJRA 3SRRX 3JSUA 1IA2A 1VDRA 1J3KA 3DL5A 3EEKA 1MVSA 3JTWA 4ECKA 3SR5X 1DRAA 4NX7A 4LAGX 3F0QX 3HJ3A 3KY8A 1DDSA 6DFRA 3SA1A 4P3QA 3ROAA 5HT4A 1RX7A 3NXYA 1RA8A 3SGYA 1DG8A 4NX6A 5DXVA 2LF1A 1AOEA 1J3IA 1DRHA 4G8ZX 4PTJA 3FS6A 4KL9A 2INQA 5HPBA 1LUDA 4HA7A 3UM8A 4FGGA 4P66A 4XT5A 4PSSA 3QLXA 1PD9A 3NRRA 1BZFA 1U70A 4I13A 3SRUX 5HSRA 1RG7A 3QLZA 2BL9A 4QJZD 3D84X 3DAUA 4KNEA 4KJLA 4G95A 4PDJA 1RX3A 4EIZA 4DFRA 3CD2A 1AI9A 4TU5X 1SEJA 4XRBA 4KJKA 2BLBA 3QG2A 3FYWX 5CCCA 1DHFA 3NZDA 3K45A 2B3ZA 4KEBA 3RO9A 3VCOA 2FZHA 3FY9X 1QZFA 2FZIA 5U27A 3GHCA 4EIGA 1HFQA 1RX2A 3F0VX 3K2HA 5JA3A 3GHVA 3CL9A 4DDRA 2C2TA 4G3MA 4H95A 5JG0X 2AZNA 4PTHA 3M08A 1DR3A 2XW7A 3NXVA 3I3RA 4H98A 3JW3A 1DREA 4M7UA 1HFRA 5HF2X 1DYJA 4Q67A 2DRCA 4QLFA 3QL0A 1J3JA 3GI2A 3E0BA 3NZCX 4FHBA 2ZZAA 5HQYA 2ITHA 1CD2A 1DYIA 2HXVA 3S7AA 2OIPA 3EEMA 3QLSA 3GYFA 3LG4A 3TD8A 2W9GA 5HT5A 3M09A 1JUVA 1DLRA 5HQZA 5HVEA 2ANOA 4IXGX 2O7PA 5ECXA 1S3WA 3F91A 4M7VA 2CIGA 3UM6A 1DR7A 3SRSX 3OCHA 3FY8X 4RGCA 2W3WA 4QLGA 2QK8A 3R33A 4XECX 2HQPA 4ELGA 3FQVA 4XT4A 4DPDA 3KGYA 3EEJA 3F8YA 3FL8A 1RF7A 1RX5A 3FRAX 1DDRA 1OHKA 1PDBA 3S9UA 2H2QA 3DL6A 1DR1A 5EAJA 3FQFA 3QLYA 2L28A 1IA1A 1DF7A 8DFRA 4EILA 4ELFA 2DHFA 4XE6X 4M6LA 3DGAA 1DR5A 4Q0DA 3QLWA 3L3RA 4XT8A 3JW5A 4DP3A 3D80A 1RA3A 3S3VA 4OSGA 2KGKA 4Q6AA 4QHVA 4LAHX 4X5GA 1VJ3A 1RE7A 1RX8A 3IRNA 4KBNA 3F0SX 1JOLA 4X5HA 4CD2A 3FL9A 1RX4A 5DFRA 4M6JA 3FQZA 1AO8A 3TQAA 1DISA 4PSYA 4IXED 3EX8A 1RA1A 3F0XX 3IROA 5U26A 1DIUA 3CSEA 3NTZA 1S3VA 1RX9A 3ZPCA 2HM9A 3FREX 3JWFA 3QYOA 1RA9A 3INVA 3NZ6X 2C2SA 1M78A 1MVTA 2W3AA 3FRBX 1S3UA 3SAIA 3F0UX 3SRQX 3UM5A 1RA2A 4KY8A 2W9TA 1HFPA 5HVBA 2D5NA 1DG5A 2OBCA 7DFRA 1DYHA 4QI9A 2GD9A 1BOZA 3FQ0A 1DLSA 1LY3A 2FZJA 4HA9A 4M6KA 1DR2A 1PD8A 3JWCA 5HUIA 4LEKX 3IA5A 5HI6A 3HBBA 1U72A 1OHJA 3CLBA 1DHJA 1JOMA 3I8AX 1DR4A 3JWMA 1RB3A 3TQBA 4LAEX 2P4GA 2JYBA 5FDAA 4KM0A 1DR6A 3QGTA 2W3MA 3FQOA 1RB2A 1DYRA 4X5JA 2W9HA 5HSUA 3ZPGA 4XT7A 3N0HA 3QFXA 3K47A 1LY4A 2G6VA 4PSTA 1TDRA 4QJCA 4QLEA 1D1GA 3NZ9X 4DPHA 1KLKA 4X5IA 2W9SA 1YHOA 4XT6A 3JVXA 5E8QA 3SRWX 4HOEA 3EELA 5CC9A 4ELEA 4KYAA 1IA4A
chains in the Genus database with same CATH superfamily
1S3YA 3FRDX 1RX1A 3RG9A 2ANQA 3FYVX 4FGHA 3DRCA 3QYLA 3NXRA 3DFRA 1DAJA 2W3VA 3IX9A 1KMSA 3QLRA 3OAFA 4X5FA 1E26A 3QL3A 1CZ3A 3NU0A 3DATA 4ELHA 3SH2A 1RH3A 4HOFA 1M79A 4IXFX 2CD2A 3IRMA 2BLAA 3NXXA 3Q1HA 1DHIA 5ECCA 3KFYA 3TQ8A 1DRBA 3NXTA 3FRFX 4P3RA 1ZDRA 1M7AA 3F0BX 4KLXA 1KMVA 3IA4A 3K74A 1DG7A 3NZBX 3KJSA 4P68A 1RD7A 1RX6A 4H96A 1IA3A 3TQ9A 1RC4A 4H97A 4KFJA 4HOGA 3JWKA 1DRFA 4GH8A 4M2XA 4KD7A 3GHWA 4I1NA 3NZAX 3DG8A 4KJJA 4EJ1A 4OR7A 3SA2A 3SQYX 3F8ZA 2W3BA 2D0KA 3EIGA 3NXOA 4Q0EA 4ELBA 3FQCA 5HF0X 4KAKA 4KM2A 4KY4A 1U71A 2BLCA 3KJRA 3SRRX 3JSUA 1IA2A 1VDRA 1J3KA 3DL5A 3EEKA 1MVSA 3JTWA 4ECKA 3SR5X 1DRAA 4NX7A 4LAGX 3F0QX 3HJ3A 3KY8A 1DDSA 6DFRA 3SA1A 4P3QA 3ROAA 5HT4A 1RX7A 3NXYA 1RA8A 3SGYA 1DG8A 4NX6A 5DXVA 2LF1A 1AOEA 1J3IA 1DRHA 4G8ZX 4PTJA 3FS6A 4KL9A 2INQA 5HPBA 1LUDA 4HA7A 3UM8A 4FGGA 4P66A 4XT5A 4PSSA 3QLXA 1PD9A 3NRRA 1BZFA 1U70A 4I13A 3SRUX 5HSRA 1RG7A 3QLZA 2BL9A 4QJZD 3D84X 3DAUA 4KNEA 4KJLA 4G95A 4PDJA 1RX3A 4EIZA 4DFRA 3CD2A 1AI9A 4TU5X 1SEJA 4XRBA 4KJKA 2BLBA 3QG2A 3FYWX 5CCCA 1DHFA 3NZDA 3K45A 2B3ZA 4KEBA 3RO9A 3VCOA 2FZHA 3FY9X 1QZFA 2FZIA 5U27A 3GHCA 4EIGA 1HFQA 1RX2A 3F0VX 3K2HA 5JA3A 3GHVA 3CL9A 4DDRA 2C2TA 4G3MA 4H95A 5JG0X 2AZNA 4PTHA 3M08A 1DR3A 2XW7A 3NXVA 3I3RA 4H98A 3JW3A 1DREA 4M7UA 1HFRA 5HF2X 1DYJA 4Q67A 2DRCA 4QLFA 3QL0A 1J3JA 3GI2A 3E0BA 3NZCX 4FHBA 2ZZAA 5HQYA 2ITHA 1CD2A 1DYIA 2HXVA 3S7AA 2OIPA 3EEMA 3QLSA 3GYFA 3LG4A 3TD8A 2W9GA 5HT5A 3M09A 1JUVA 1DLRA 5HQZA 5HVEA 2ANOA 4IXGX 2O7PA 5ECXA 1S3WA 3F91A 4M7VA 2CIGA 3UM6A 1DR7A 3SRSX 3OCHA 3FY8X 4RGCA 2W3WA 4QLGA 2QK8A 3R33A 4XECX 2HQPA 4ELGA 3FQVA 4XT4A 4DPDA 3KGYA 3EEJA 3F8YA 3FL8A 1RF7A 1RX5A 3FRAX 1DDRA 1OHKA 1PDBA 3S9UA 2H2QA 3DL6A 1DR1A 5EAJA 3FQFA 3QLYA 2L28A 1IA1A 1DF7A 8DFRA 4EILA 4ELFA 2DHFA 4XE6X 4M6LA 3DGAA 1DR5A 4Q0DA 3QLWA 3L3RA 4XT8A 3JW5A 4DP3A 3D80A 1RA3A 3S3VA 4OSGA 2KGKA 4Q6AA 4QHVA 4LAHX 4X5GA 1VJ3A 1RE7A 1RX8A 3IRNA 4KBNA 3F0SX 1JOLA 4X5HA 4CD2A 3FL9A 1RX4A 5DFRA 4M6JA 3FQZA 1AO8A 3TQAA 1DISA 4PSYA 4IXED 3EX8A 1RA1A 3F0XX 3IROA 5U26A 1DIUA 3CSEA 3NTZA 1S3VA 1RX9A 3ZPCA 2HM9A 3FREX 3JWFA 3QYOA 1RA9A 3INVA 3NZ6X 2C2SA 1M78A 1MVTA 2W3AA 3FRBX 1S3UA 3SAIA 3F0UX 3SRQX 3UM5A 1RA2A 4KY8A 2W9TA 1HFPA 5HVBA 2D5NA 1DG5A 2OBCA 7DFRA 1DYHA 4QI9A 2GD9A 1BOZA 3FQ0A 1DLSA 1LY3A 2FZJA 4HA9A 4M6KA 1DR2A 1PD8A 3JWCA 5HUIA 4LEKX 3IA5A 5HI6A 3HBBA 1U72A 1OHJA 3CLBA 1DHJA 1JOMA 3I8AX 1DR4A 3JWMA 1RB3A 3TQBA 4LAEX 2P4GA 2JYBA 5FDAA 4KM0A 1DR6A 3QGTA 2W3MA 3FQOA 1RB2A 1DYRA 4X5JA 2W9HA 5HSUA 3ZPGA 4XT7A 3N0HA 3QFXA 3K47A 1LY4A 2G6VA 4PSTA 1TDRA 4QJCA 4QLEA 1D1GA 3NZ9X 4DPHA 1KLKA 4X5IA 2W9SA 1YHOA 4XT6A 3JVXA 5E8QA 3SRWX 4HOEA 3EELA 5CC9A 4ELEA 4KYAA 1IA4A
chains in the Genus database with same CATH topology
1S3YA 3FRDX 1RX1A 3RG9A 2ANQA 3FYVX 4FGHA 3DRCA 3QYLA 3NXRA 3DFRA 1DAJA 2W3VA 3IX9A 1KMSA 3QLRA 3OAFA 4X5FA 1E26A 3QL3A 1CZ3A 3NU0A 3DATA 4ELHA 3SH2A 1RH3A 4HOFA 1M79A 4IXFX 2CD2A 3IRMA 2BLAA 3NXXA 3Q1HA 1DHIA 5ECCA 3KFYA 3TQ8A 1DRBA 3NXTA 3FRFX 4P3RA 1ZDRA 1M7AA 3F0BX 4KLXA 1KMVA 3IA4A 3K74A 1DG7A 3NZBX 3KJSA 4P68A 1RD7A 1RX6A 4H96A 1IA3A 3TQ9A 1RC4A 4H97A 4KFJA 4HOGA 3JWKA 1DRFA 4GH8A 4M2XA 4KD7A 3GHWA 4I1NA 3NZAX 3DG8A 4KJJA 4EJ1A 4OR7A 3SA2A 3SQYX 3F8ZA 2W3BA 2D0KA 3EIGA 3NXOA 4Q0EA 4ELBA 3FQCA 5HF0X 4KAKA 4KM2A 4KY4A 1U71A 2BLCA 3KJRA 3SRRX 3JSUA 1IA2A 1VDRA 1J3KA 3DL5A 3EEKA 1MVSA 3JTWA 4ECKA 3SR5X 1DRAA 4NX7A 4LAGX 3F0QX 3HJ3A 3KY8A 1DDSA 6DFRA 3SA1A 4P3QA 3ROAA 5HT4A 1RX7A 3NXYA 1RA8A 3SGYA 1DG8A 4NX6A 5DXVA 2LF1A 1AOEA 1J3IA 1DRHA 4G8ZX 4PTJA 3FS6A 4KL9A 2INQA 5HPBA 1LUDA 4HA7A 3UM8A 4FGGA 4P66A 4XT5A 4PSSA 3QLXA 1PD9A 3NRRA 1BZFA 1U70A 4I13A 3SRUX 5HSRA 1RG7A 3QLZA 2BL9A 4QJZD 3D84X 3DAUA 4KNEA 4KJLA 4G95A 4PDJA 1RX3A 4EIZA 4DFRA 3CD2A 1AI9A 4TU5X 1SEJA 4XRBA 4KJKA 2BLBA 3QG2A 3FYWX 5CCCA 1DHFA 3NZDA 3K45A 2B3ZA 4KEBA 3RO9A 3VCOA 2FZHA 3FY9X 1QZFA 2FZIA 5U27A 3GHCA 4EIGA 1HFQA 1RX2A 3F0VX 3K2HA 5JA3A 3GHVA 3CL9A 4DDRA 2C2TA 4G3MA 4H95A 5JG0X 2AZNA 4PTHA 3M08A 1DR3A 2XW7A 3NXVA 3I3RA 4H98A 3JW3A 1DREA 4M7UA 1HFRA 5HF2X 1DYJA 4Q67A 2DRCA 4QLFA 3QL0A 1J3JA 3GI2A 3E0BA 3NZCX 4FHBA 2ZZAA 5HQYA 2ITHA 1CD2A 1DYIA 2HXVA 3S7AA 2OIPA 3EEMA 3QLSA 3GYFA 3LG4A 3TD8A 2W9GA 5HT5A 3M09A 1JUVA 1DLRA 5HQZA 5HVEA 2ANOA 4IXGX 2O7PA 5ECXA 1S3WA 3F91A 4M7VA 2CIGA 3UM6A 1DR7A 3SRSX 3OCHA 3FY8X 4RGCA 2W3WA 4QLGA 2QK8A 3R33A 4XECX 2HQPA 4ELGA 3FQVA 4XT4A 4DPDA 3KGYA 3EEJA 3F8YA 3FL8A 1RF7A 1RX5A 3FRAX 1DDRA 1OHKA 1PDBA 3S9UA 2H2QA 3DL6A 1DR1A 5EAJA 3FQFA 3QLYA 2L28A 1IA1A 1DF7A 8DFRA 4EILA 4ELFA 2DHFA 4XE6X 4M6LA 3DGAA 1DR5A 4Q0DA 3QLWA 3L3RA 4XT8A 3JW5A 4DP3A 3D80A 1RA3A 3S3VA 4OSGA 2KGKA 4Q6AA 4QHVA 4LAHX 4X5GA 1VJ3A 1RE7A 1RX8A 3IRNA 4KBNA 3F0SX 1JOLA 4X5HA 4CD2A 3FL9A 1RX4A 5DFRA 4M6JA 3FQZA 1AO8A 3TQAA 1DISA 4PSYA 4IXED 3EX8A 1RA1A 3F0XX 3IROA 5U26A 1DIUA 3CSEA 3NTZA 1S3VA 1RX9A 3ZPCA 2HM9A 3FREX 3JWFA 3QYOA 1RA9A 3INVA 3NZ6X 2C2SA 1M78A 1MVTA 2W3AA 3FRBX 1S3UA 3SAIA 3F0UX 3SRQX 3UM5A 1RA2A 4KY8A 2W9TA 1HFPA 5HVBA 2D5NA 1DG5A 2OBCA 7DFRA 1DYHA 4QI9A 2GD9A 1BOZA 3FQ0A 1DLSA 1LY3A 2FZJA 4HA9A 4M6KA 1DR2A 1PD8A 3JWCA 5HUIA 4LEKX 3IA5A 5HI6A 3HBBA 1U72A 1OHJA 3CLBA 1DHJA 1JOMA 3I8AX 1DR4A 3JWMA 1RB3A 3TQBA 4LAEX 2P4GA 2JYBA 5FDAA 4KM0A 1DR6A 3QGTA 2W3MA 3FQOA 1RB2A 1DYRA 4X5JA 2W9HA 5HSUA 3ZPGA 4XT7A 3N0HA 3QFXA 3K47A 1LY4A 2G6VA 4PSTA 1TDRA 4QJCA 4QLEA 1D1GA 3NZ9X 4DPHA 1KLKA 4X5IA 2W9SA 1YHOA 4XT6A 3JVXA 5E8QA 3SRWX 4HOEA 3EELA 5CC9A 4ELEA 4KYAA 1IA4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S3Y A;  3FRD X;  1RX1 A;  3RG9 A;  2ANQ A;  3FYV X;  4FGH A;  3DRC A;  3QYL A;  3NXR A;  3DFR A;  1DAJ A;  2W3V A;  3IX9 A;  1KMS A;  3QLR A;  3OAF A;  4X5F A;  1E26 A;  3QL3 A;  1CZ3 A;  3NU0 A;  3DAT A;  4ELH A;  3SH2 A;  1RH3 A;  4HOF A;  1M79 A;  4IXF X;  2CD2 A;  3IRM A;  2BLA A;  3NXX A;  3Q1H A;  1DHI A;  5ECC A;  3KFY A;  3TQ8 A;  1DRB A;  3NXT A;  3FRF X;  4P3R A;  1ZDR A;  1M7A A;  3F0B X;  4KLX A;  1KMV A;  3IA4 A;  3K74 A;  1DG7 A;  3NZB X;  3KJS A;  4P68 A;  1RD7 A;  1RX6 A;  4H96 A;  1IA3 A;  3TQ9 A;  1RC4 A;  4H97 A;  4KFJ A;  4HOG A;  3JWK A;  1DRF A;  4GH8 A;  4M2X A;  4KD7 A;  3GHW A;  4I1N A;  3NZA X;  3DG8 A;  4KJJ A;  4EJ1 A;  4OR7 A;  3SA2 A;  3SQY X;  3F8Z A;  2W3B A;  2D0K A;  3EIG A;  3NXO A;  4Q0E A;  4ELB A;  3FQC A;  5HF0 X;  4KAK A;  4KM2 A;  4KY4 A;  1U71 A;  2BLC A;  3KJR A;  3SRR X;  3JSU A;  1IA2 A;  1VDR A;  1J3K A;  3DL5 A;  3EEK A;  1MVS A;  3JTW A;  4ECK A;  3SR5 X;  1DRA A;  4NX7 A;  4LAG X;  3F0Q X;  3HJ3 A;  3KY8 A;  1DDS A;  6DFR A;  3SA1 A;  4P3Q A;  3ROA A;  5HT4 A;  1RX7 A;  3NXY A;  1RA8 A;  3SGY A;  1DG8 A;  4NX6 A;  5DXV A;  2LF1 A;  1AOE A;  1J3I A;  1DRH A;  4G8Z X;  4PTJ A;  3FS6 A;  4KL9 A;  2INQ A;  5HPB A;  1LUD A;  4HA7 A;  3UM8 A;  4FGG A;  4P66 A;  4XT5 A;  4PSS A;  3QLX A;  1PD9 A;  3NRR A;  1BZF A;  1U70 A;  4I13 A;  3SRU X;  5HSR A;  1RG7 A;  3QLZ A;  2BL9 A;  4QJZ D;  3D84 X;  3DAU A;  4KNE A;  4KJL A;  4G95 A;  4PDJ A;  1RX3 A;  4EIZ A;  4DFR A;  3CD2 A;  1AI9 A;  4TU5 X;  1SEJ A;  4XRB A;  4KJK A;  2BLB A;  3QG2 A;  3FYW X;  5CCC A;  1DHF A;  3NZD A;  3K45 A;  2B3Z A;  4KEB A;  3RO9 A;  3VCO A;  2FZH A;  3FY9 X;  1QZF A;  2FZI A;  5U27 A;  3GHC A;  4EIG A;  1HFQ A;  1RX2 A;  3F0V X;  3K2H A;  5JA3 A;  3GHV A;  3CL9 A;  4DDR A;  2C2T A;  4G3M A;  4H95 A;  5JG0 X;  2AZN A;  4PTH A;  3M08 A;  1DR3 A;  2XW7 A;  3NXV A;  3I3R A;  4H98 A;  3JW3 A;  1DRE A;  4M7U A;  1HFR A;  5HF2 X;  1DYJ A;  4Q67 A;  2DRC A;  4QLF A;  3QL0 A;  1J3J A;  3GI2 A;  3E0B A;  3NZC X;  4FHB A;  2ZZA A;  5HQY A;  2ITH A;  1CD2 A;  1DYI A;  2HXV A;  3S7A A;  2OIP A;  3EEM A;  3QLS A;  3GYF A;  3LG4 A;  3TD8 A;  2W9G A;  5HT5 A;  3M09 A;  1JUV A;  1DLR A;  5HQZ A;  5HVE A;  2ANO A;  4IXG X;  2O7P A;  5ECX A;  1S3W A;  3F91 A;  4M7V A;  2CIG A;  3UM6 A;  1DR7 A;  3SRS X;  3OCH A;  3FY8 X;  4RGC A;  2W3W A;  4QLG A;  2QK8 A;  3R33 A;  4XEC X;  2HQP A;  4ELG A;  3FQV A;  4XT4 A;  4DPD A;  3KGY A;  3EEJ A;  3F8Y A;  3FL8 A;  1RF7 A;  1RX5 A;  3FRA X;  1DDR A;  1OHK A;  1PDB A;  3S9U A;  2H2Q A;  3DL6 A;  1DR1 A;  5EAJ A;  3FQF A;  3QLY A;  2L28 A;  1IA1 A;  1DF7 A;  8DFR A;  4EIL A;  4ELF A;  2DHF A;  4XE6 X;  4M6L A;  3DGA A;  1DR5 A;  4Q0D A;  3QLW A;  3L3R A;  4XT8 A;  3JW5 A;  4DP3 A;  3D80 A;  1RA3 A;  3S3V A;  4OSG A;  2KGK A;  4Q6A A;  4QHV A;  4LAH X;  4X5G A;  1VJ3 A;  1RE7 A;  1RX8 A;  3IRN A;  4KBN A;  3F0S X;  1JOL A;  4X5H A;  4CD2 A;  3FL9 A;  1RX4 A;  5DFR A;  4M6J A;  3FQZ A;  1AO8 A;  3TQA A;  1DIS A;  4PSY A;  4IXE D;  3EX8 A;  1RA1 A;  3F0X X;  3IRO A;  5U26 A;  1DIU A;  3CSE A;  3NTZ A;  1S3V A;  1RX9 A;  3ZPC A;  2HM9 A;  3FRE X;  3JWF A;  3QYO A;  1RA9 A;  3INV A;  3NZ6 X;  2C2S A;  1M78 A;  1MVT A;  2W3A A;  3FRB X;  1S3U A;  3SAI A;  3F0U X;  3SRQ X;  3UM5 A;  1RA2 A;  4KY8 A;  2W9T A;  1HFP A;  5HVB A;  2D5N A;  1DG5 A;  2OBC A;  7DFR A;  1DYH A;  4QI9 A;  2GD9 A;  1BOZ A;  3FQ0 A;  1DLS A;  1LY3 A;  2FZJ A;  4HA9 A;  4M6K A;  1DR2 A;  1PD8 A;  3JWC A;  5HUI A;  4LEK X;  3IA5 A;  5HI6 A;  3HBB A;  1U72 A;  1OHJ A;  3CLB A;  1DHJ A;  1JOM A;  3I8A X;  1DR4 A;  3JWM A;  1RB3 A;  3TQB A;  4LAE X;  2P4G A;  2JYB A;  5FDA A;  4KM0 A;  1DR6 A;  3QGT A;  2W3M A;  3FQO A;  1RB2 A;  1DYR A;  4X5J A;  2W9H A;  5HSU A;  3ZPG A;  4XT7 A;  3N0H A;  3QFX A;  3K47 A;  1LY4 A;  2G6V A;  4PST A;  1TDR A;  4QJC A;  4QLE A;  1D1G A;  3NZ9 X;  4DPH A;  1KLK A;  4X5I A;  2W9S A;  1YHO A;  4XT6 A;  3JVX A;  5E8Q A;  3SRW X;  4HOE A;  3EEL A;  5CC9 A;  4ELE A;  4KYA A;  1IA4 A; 
#chains in the Genus database with same CATH topology
 1S3Y A;  3FRD X;  1RX1 A;  3RG9 A;  2ANQ A;  3FYV X;  4FGH A;  3DRC A;  3QYL A;  3NXR A;  3DFR A;  1DAJ A;  2W3V A;  3IX9 A;  1KMS A;  3QLR A;  3OAF A;  4X5F A;  1E26 A;  3QL3 A;  1CZ3 A;  3NU0 A;  3DAT A;  4ELH A;  3SH2 A;  1RH3 A;  4HOF A;  1M79 A;  4IXF X;  2CD2 A;  3IRM A;  2BLA A;  3NXX A;  3Q1H A;  1DHI A;  5ECC A;  3KFY A;  3TQ8 A;  1DRB A;  3NXT A;  3FRF X;  4P3R A;  1ZDR A;  1M7A A;  3F0B X;  4KLX A;  1KMV A;  3IA4 A;  3K74 A;  1DG7 A;  3NZB X;  3KJS A;  4P68 A;  1RD7 A;  1RX6 A;  4H96 A;  1IA3 A;  3TQ9 A;  1RC4 A;  4H97 A;  4KFJ A;  4HOG A;  3JWK A;  1DRF A;  4GH8 A;  4M2X A;  4KD7 A;  3GHW A;  4I1N A;  3NZA X;  3DG8 A;  4KJJ A;  4EJ1 A;  4OR7 A;  3SA2 A;  3SQY X;  3F8Z A;  2W3B A;  2D0K A;  3EIG A;  3NXO A;  4Q0E A;  4ELB A;  3FQC A;  5HF0 X;  4KAK A;  4KM2 A;  4KY4 A;  1U71 A;  2BLC A;  3KJR A;  3SRR X;  3JSU A;  1IA2 A;  1VDR A;  1J3K A;  3DL5 A;  3EEK A;  1MVS A;  3JTW A;  4ECK A;  3SR5 X;  1DRA A;  4NX7 A;  4LAG X;  3F0Q X;  3HJ3 A;  3KY8 A;  1DDS A;  6DFR A;  3SA1 A;  4P3Q A;  3ROA A;  5HT4 A;  1RX7 A;  3NXY A;  1RA8 A;  3SGY A;  1DG8 A;  4NX6 A;  5DXV A;  2LF1 A;  1AOE A;  1J3I A;  1DRH A;  4G8Z X;  4PTJ A;  3FS6 A;  4KL9 A;  2INQ A;  5HPB A;  1LUD A;  4HA7 A;  3UM8 A;  4FGG A;  4P66 A;  4XT5 A;  4PSS A;  3QLX A;  1PD9 A;  3NRR A;  1BZF A;  1U70 A;  4I13 A;  3SRU X;  5HSR A;  1RG7 A;  3QLZ A;  2BL9 A;  4QJZ D;  3D84 X;  3DAU A;  4KNE A;  4KJL A;  4G95 A;  4PDJ A;  1RX3 A;  4EIZ A;  4DFR A;  3CD2 A;  1AI9 A;  4TU5 X;  1SEJ A;  4XRB A;  4KJK A;  2BLB A;  3QG2 A;  3FYW X;  5CCC A;  1DHF A;  3NZD A;  3K45 A;  2B3Z A;  4KEB A;  3RO9 A;  3VCO A;  2FZH A;  3FY9 X;  1QZF A;  2FZI A;  5U27 A;  3GHC A;  4EIG A;  1HFQ A;  1RX2 A;  3F0V X;  3K2H A;  5JA3 A;  3GHV A;  3CL9 A;  4DDR A;  2C2T A;  4G3M A;  4H95 A;  5JG0 X;  2AZN A;  4PTH A;  3M08 A;  1DR3 A;  2XW7 A;  3NXV A;  3I3R A;  4H98 A;  3JW3 A;  1DRE A;  4M7U A;  1HFR A;  5HF2 X;  1DYJ A;  4Q67 A;  2DRC A;  4QLF A;  3QL0 A;  1J3J A;  3GI2 A;  3E0B A;  3NZC X;  4FHB A;  2ZZA A;  5HQY A;  2ITH A;  1CD2 A;  1DYI A;  2HXV A;  3S7A A;  2OIP A;  3EEM A;  3QLS A;  3GYF A;  3LG4 A;  3TD8 A;  2W9G A;  5HT5 A;  3M09 A;  1JUV A;  1DLR A;  5HQZ A;  5HVE A;  2ANO A;  4IXG X;  2O7P A;  5ECX A;  1S3W A;  3F91 A;  4M7V A;  2CIG A;  3UM6 A;  1DR7 A;  3SRS X;  3OCH A;  3FY8 X;  4RGC A;  2W3W A;  4QLG A;  2QK8 A;  3R33 A;  4XEC X;  2HQP A;  4ELG A;  3FQV A;  4XT4 A;  4DPD A;  3KGY A;  3EEJ A;  3F8Y A;  3FL8 A;  1RF7 A;  1RX5 A;  3FRA X;  1DDR A;  1OHK A;  1PDB A;  3S9U A;  2H2Q A;  3DL6 A;  1DR1 A;  5EAJ A;  3FQF A;  3QLY A;  2L28 A;  1IA1 A;  1DF7 A;  8DFR A;  4EIL A;  4ELF A;  2DHF A;  4XE6 X;  4M6L A;  3DGA A;  1DR5 A;  4Q0D A;  3QLW A;  3L3R A;  4XT8 A;  3JW5 A;  4DP3 A;  3D80 A;  1RA3 A;  3S3V A;  4OSG A;  2KGK A;  4Q6A A;  4QHV A;  4LAH X;  4X5G A;  1VJ3 A;  1RE7 A;  1RX8 A;  3IRN A;  4KBN A;  3F0S X;  1JOL A;  4X5H A;  4CD2 A;  3FL9 A;  1RX4 A;  5DFR A;  4M6J A;  3FQZ A;  1AO8 A;  3TQA A;  1DIS A;  4PSY A;  4IXE D;  3EX8 A;  1RA1 A;  3F0X X;  3IRO A;  5U26 A;  1DIU A;  3CSE A;  3NTZ A;  1S3V A;  1RX9 A;  3ZPC A;  2HM9 A;  3FRE X;  3JWF A;  3QYO A;  1RA9 A;  3INV A;  3NZ6 X;  2C2S A;  1M78 A;  1MVT A;  2W3A A;  3FRB X;  1S3U A;  3SAI A;  3F0U X;  3SRQ X;  3UM5 A;  1RA2 A;  4KY8 A;  2W9T A;  1HFP A;  5HVB A;  2D5N A;  1DG5 A;  2OBC A;  7DFR A;  1DYH A;  4QI9 A;  2GD9 A;  1BOZ A;  3FQ0 A;  1DLS A;  1LY3 A;  2FZJ A;  4HA9 A;  4M6K A;  1DR2 A;  1PD8 A;  3JWC A;  5HUI A;  4LEK X;  3IA5 A;  5HI6 A;  3HBB A;  1U72 A;  1OHJ A;  3CLB A;  1DHJ A;  1JOM A;  3I8A X;  1DR4 A;  3JWM A;  1RB3 A;  3TQB A;  4LAE X;  2P4G A;  2JYB A;  5FDA A;  4KM0 A;  1DR6 A;  3QGT A;  2W3M A;  3FQO A;  1RB2 A;  1DYR A;  4X5J A;  2W9H A;  5HSU A;  3ZPG A;  4XT7 A;  3N0H A;  3QFX A;  3K47 A;  1LY4 A;  2G6V A;  4PST A;  1TDR A;  4QJC A;  4QLE A;  1D1G A;  3NZ9 X;  4DPH A;  1KLK A;  4X5I A;  2W9S A;  1YHO A;  4XT6 A;  3JVX A;  5E8Q A;  3SRW X;  4HOE A;  3EEL A;  5CC9 A;  4ELE A;  4KYA A;  1IA4 A; 
#chains in the Genus database with same CATH homology
 1S3Y A;  3FRD X;  1RX1 A;  3RG9 A;  2ANQ A;  3FYV X;  4FGH A;  3DRC A;  3QYL A;  3NXR A;  3DFR A;  1DAJ A;  2W3V A;  3IX9 A;  1KMS A;  3QLR A;  3OAF A;  4X5F A;  1E26 A;  3QL3 A;  1CZ3 A;  3NU0 A;  3DAT A;  4ELH A;  3SH2 A;  1RH3 A;  4HOF A;  1M79 A;  4IXF X;  2CD2 A;  3IRM A;  2BLA A;  3NXX A;  3Q1H A;  1DHI A;  5ECC A;  3KFY A;  3TQ8 A;  1DRB A;  3NXT A;  3FRF X;  4P3R A;  1ZDR A;  1M7A A;  3F0B X;  4KLX A;  1KMV A;  3IA4 A;  3K74 A;  1DG7 A;  3NZB X;  3KJS A;  4P68 A;  1RD7 A;  1RX6 A;  4H96 A;  1IA3 A;  3TQ9 A;  1RC4 A;  4H97 A;  4KFJ A;  4HOG A;  3JWK A;  1DRF A;  4GH8 A;  4M2X A;  4KD7 A;  3GHW A;  4I1N A;  3NZA X;  3DG8 A;  4KJJ A;  4EJ1 A;  4OR7 A;  3SA2 A;  3SQY X;  3F8Z A;  2W3B A;  2D0K A;  3EIG A;  3NXO A;  4Q0E A;  4ELB A;  3FQC A;  5HF0 X;  4KAK A;  4KM2 A;  4KY4 A;  1U71 A;  2BLC A;  3KJR A;  3SRR X;  3JSU A;  1IA2 A;  1VDR A;  1J3K A;  3DL5 A;  3EEK A;  1MVS A;  3JTW A;  4ECK A;  3SR5 X;  1DRA A;  4NX7 A;  4LAG X;  3F0Q X;  3HJ3 A;  3KY8 A;  1DDS A;  6DFR A;  3SA1 A;  4P3Q A;  3ROA A;  5HT4 A;  1RX7 A;  3NXY A;  1RA8 A;  3SGY A;  1DG8 A;  4NX6 A;  5DXV A;  2LF1 A;  1AOE A;  1J3I A;  1DRH A;  4G8Z X;  4PTJ A;  3FS6 A;  4KL9 A;  2INQ A;  5HPB A;  1LUD A;  4HA7 A;  3UM8 A;  4FGG A;  4P66 A;  4XT5 A;  4PSS A;  3QLX A;  1PD9 A;  3NRR A;  1BZF A;  1U70 A;  4I13 A;  3SRU X;  5HSR A;  1RG7 A;  3QLZ A;  2BL9 A;  4QJZ D;  3D84 X;  3DAU A;  4KNE A;  4KJL A;  4G95 A;  4PDJ A;  1RX3 A;  4EIZ A;  4DFR A;  3CD2 A;  1AI9 A;  4TU5 X;  1SEJ A;  4XRB A;  4KJK A;  2BLB A;  3QG2 A;  3FYW X;  5CCC A;  1DHF A;  3NZD A;  3K45 A;  2B3Z A;  4KEB A;  3RO9 A;  3VCO A;  2FZH A;  3FY9 X;  1QZF A;  2FZI A;  5U27 A;  3GHC A;  4EIG A;  1HFQ A;  1RX2 A;  3F0V X;  3K2H A;  5JA3 A;  3GHV A;  3CL9 A;  4DDR A;  2C2T A;  4G3M A;  4H95 A;  5JG0 X;  2AZN A;  4PTH A;  3M08 A;  1DR3 A;  2XW7 A;  3NXV A;  3I3R A;  4H98 A;  3JW3 A;  1DRE A;  4M7U A;  1HFR A;  5HF2 X;  1DYJ A;  4Q67 A;  2DRC A;  4QLF A;  3QL0 A;  1J3J A;  3GI2 A;  3E0B A;  3NZC X;  4FHB A;  2ZZA A;  5HQY A;  2ITH A;  1CD2 A;  1DYI A;  2HXV A;  3S7A A;  2OIP A;  3EEM A;  3QLS A;  3GYF A;  3LG4 A;  3TD8 A;  2W9G A;  5HT5 A;  3M09 A;  1JUV A;  1DLR A;  5HQZ A;  5HVE A;  2ANO A;  4IXG X;  2O7P A;  5ECX A;  1S3W A;  3F91 A;  4M7V A;  2CIG A;  3UM6 A;  1DR7 A;  3SRS X;  3OCH A;  3FY8 X;  4RGC A;  2W3W A;  4QLG A;  2QK8 A;  3R33 A;  4XEC X;  2HQP A;  4ELG A;  3FQV A;  4XT4 A;  4DPD A;  3KGY A;  3EEJ A;  3F8Y A;  3FL8 A;  1RF7 A;  1RX5 A;  3FRA X;  1DDR A;  1OHK A;  1PDB A;  3S9U A;  2H2Q A;  3DL6 A;  1DR1 A;  5EAJ A;  3FQF A;  3QLY A;  2L28 A;  1IA1 A;  1DF7 A;  8DFR A;  4EIL A;  4ELF A;  2DHF A;  4XE6 X;  4M6L A;  3DGA A;  1DR5 A;  4Q0D A;  3QLW A;  3L3R A;  4XT8 A;  3JW5 A;  4DP3 A;  3D80 A;  1RA3 A;  3S3V A;  4OSG A;  2KGK A;  4Q6A A;  4QHV A;  4LAH X;  4X5G A;  1VJ3 A;  1RE7 A;  1RX8 A;  3IRN A;  4KBN A;  3F0S X;  1JOL A;  4X5H A;  4CD2 A;  3FL9 A;  1RX4 A;  5DFR A;  4M6J A;  3FQZ A;  1AO8 A;  3TQA A;  1DIS A;  4PSY A;  4IXE D;  3EX8 A;  1RA1 A;  3F0X X;  3IRO A;  5U26 A;  1DIU A;  3CSE A;  3NTZ A;  1S3V A;  1RX9 A;  3ZPC A;  2HM9 A;  3FRE X;  3JWF A;  3QYO A;  1RA9 A;  3INV A;  3NZ6 X;  2C2S A;  1M78 A;  1MVT A;  2W3A A;  3FRB X;  1S3U A;  3SAI A;  3F0U X;  3SRQ X;  3UM5 A;  1RA2 A;  4KY8 A;  2W9T A;  1HFP A;  5HVB A;  2D5N A;  1DG5 A;  2OBC A;  7DFR A;  1DYH A;  4QI9 A;  2GD9 A;  1BOZ A;  3FQ0 A;  1DLS A;  1LY3 A;  2FZJ A;  4HA9 A;  4M6K A;  1DR2 A;  1PD8 A;  3JWC A;  5HUI A;  4LEK X;  3IA5 A;  5HI6 A;  3HBB A;  1U72 A;  1OHJ A;  3CLB A;  1DHJ A;  1JOM A;  3I8A X;  1DR4 A;  3JWM A;  1RB3 A;  3TQB A;  4LAE X;  2P4G A;  2JYB A;  5FDA A;  4KM0 A;  1DR6 A;  3QGT A;  2W3M A;  3FQO A;  1RB2 A;  1DYR A;  4X5J A;  2W9H A;  5HSU A;  3ZPG A;  4XT7 A;  3N0H A;  3QFX A;  3K47 A;  1LY4 A;  2G6V A;  4PST A;  1TDR A;  4QJC A;  4QLE A;  1D1G A;  3NZ9 X;  4DPH A;  1KLK A;  4X5I A;  2W9S A;  1YHO A;  4XT6 A;  3JVX A;  5E8Q A;  3SRW X;  4HOE A;  3EEL A;  5CC9 A;  4ELE A;  4KYA A;  1IA4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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