3JVXA

Crystal structure of bacillus anthracis dihydrofolate reductase complexed with nadph and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (ucp120a)
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
166
Chain Sequence
HHHHMRVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational Studies into Trimethoprim Resistance in Bacillus anthracis Dihydrofolate Reductase
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Bacillus anthracis
molecule keywords Dihydrofolate reductase
total genus 45
structure length 166
sequence length 166
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-09-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3jvxA00
3RG9A 3UM8A 4I1NA 4KNEA 4M2XA 4EIGA 4IXED 3JTWA 1RB3A 2HXVA 3QLRA 1RX4A 4CD2A 3EEJA 3FQ0A 3UM6A 3K74A 1S3VA 1RF7A 1MVTA 3TQAA 1DHIA 1DDRA 3L3RA 4M6KA 4G8ZX 3M09A 4XRBA 1DAJA 1TDRA 5U26A 2C2TA 4M6JA 3IRNA 5EAJA 1ZDRA 4QLEA 3D84X 1JOMA 4DPHA 5HVEA 3FQVA 3SA2A 2W9GA 1DHFA 2ZZAA 3FQFA 4QHVA 4GH8A 1DYHA 4QI9A 4Q0DA 3VCOA 1RA2A 4ECKA 3NXYA 3SRUX 5HI6A 3S9UA 3SA1A 1RC4A 1QZFA 1OHJA 1RX1A 3DRCA 1YHOA 2D5NA 4LAHX 3FL9A 3QG2A 1HFPA 5HSUA 3SRWX 1DRAA 2DHFA 3SAIA 1PD9A 4PSTA 2W3BA 3FYVX 3NZAX 3TQ9A 1LY3A 5HQZA 3JW3A 3DL6A 3FQCA 3HBBA 3QLZA 4QJCA 3QFXA 5HVBA 4KL9A 1M7AA 3NZ6X 1DR1A 1S3WA 2ANOA 2W3MA 3JWMA 3QYLA 3FRBX 2W3VA 4H97A 5HF0X 3NU0A 1DR6A 1KMSA 4ELBA 4FHBA 3IRMA 3Q1HA 4KEBA 1RE7A 3F0BX 1RX8A 1DRBA 4KY8A 3RO9A 3SR5X 5DXVA 1S3UA 1BOZA 1DISA 1IA2A 4Q67A 3GHCA 4PTHA 1RA8A 1RX9A 3SRRX 8DFRA 1U71A 4X5GA 5ECCA 1DRFA 4ELEA 3KFYA 1RD7A 3EEKA 1DLSA 2C2SA 2D0KA 4IXGX 3JWKA 4ELGA 4XT6A 4XE6X 4P68A 2B3ZA 1KLKA 1U72A 3FYWX 4HOFA 4IXFX 1DG5A 1U70A 1BZFA 1VDRA 4G95A 3F0UX 4KD7A 3NXVA 3S7AA 5CCCA 4G3MA 6DFRA 3NTZA 4M7VA 3GHVA 4KM0A 3DG8A 2BLBA 4NX7A 1LUDA 3F0XX 4M6LA 3NXXA 2GD9A 1RX5A 2ANQA 3K2HA 4QLGA 1DR5A 1RX2A 4XT7A 4KFJA 1D1GA 2W3AA 3TQ8A 3N0HA 4KYAA 4OR7A 3FY9X 2INQA 4EILA 1RX7A 2BLCA 2ITHA 4ELHA 3F0QX 5U27A 3ZPGA 4QJZD 1IA3A 3FL8A 1AOEA 3NZBX 1CD2A 3SGYA 3FQOA 4XT4A 3QLXA 2AZNA 4FGHA 2W3WA 1RG7A 1KMVA 5HF2X 4PDJA 1CZ3A 3KJRA 1RH3A 3TQBA 1VJ3A 3QLWA 4KLXA 5HPBA 4X5HA 2JYBA 4H98A 4KAKA 3KY8A 4KJKA 1M79A 3FY8X 2FZIA 3EELA 4Q6AA 3DFRA 3TD8A 1IA1A 4Q0EA 2OIPA 2CIGA 5JG0X 1RA9A 4FGGA 4TU5X 4KJJA 2KGKA 1DR4A 3I8AX 1IA4A 3FRAX 1DYRA 2XW7A 3EX8A 1DF7A 4ELFA 5JA3A 3UM5A 3FS6A 3CL9A 4QLFA 1PD8A 7DFRA 1DREA 3K47A 1M78A 4KM2A 1DYIA 3IA5A 3GI2A 3GHWA 4LAEX 1LY4A 3K45A 3I3RA 1RA1A 3EIGA 5CC9A 1RA3A 3IROA 3EEMA 3JVXA 1HFQA 2CD2A 3QL0A 1JOLA 3F0VX 3ROAA 4HOGA 2HM9A 4RGCA 4KBNA 3SQYX 4KY4A 4PSYA 3DATA 5ECXA 2P4GA 1J3JA 3QLYA 1DIUA 3S3VA 1DR3A 4X5FA 4LAGX 3SH2A 3NZDA 2DRCA 3JWFA 3INVA 3R33A 3OAFA 1DRHA 1DG7A 1SEJA 4HA7A 4M7UA 4P3RA 4H95A 3QLSA 4PSSA 2HQPA 3QYOA 1AO8A 2OBCA 1S3YA 3CSEA 1DR2A 3QGTA 4XECX 3CD2A 4X5JA 3ZPCA 1E26A 2G6VA 4DFRA 4KJLA 3NXOA 3HJ3A 2W9TA 3FRFX 4DPDA 5HT5A 3IX9A 4NX6A 1DG8A 1DDSA 3JSUA 3SRSX 3JWCA 3FREX 1DLRA 1HFRA 3FQZA 2FZHA 4DDRA 1PDBA 3DL5A 4EIZA 2BL9A 4HOEA 4PTJA 3NZCX 3OCHA 3LG4A 1J3IA 2H2QA 5HUIA 3F8YA 3JW5A 3CLBA 4XT8A 5HQYA 3F0SX 3NXTA 3D80A 1DHJA 3FRDX 3IA4A 2L28A 1DR7A 3DGAA 4HA9A 2LF1A 4X5IA 2W9SA 3M08A 1DYJA 4P3QA 1JUVA 4DP3A 2QK8A 3NZ9X 4XT5A 1RX6A 3NRRA 4OSGA 4LEKX 3GYFA 3F91A 1RB2A 4P66A 4EJ1A 5DFRA 3KGYA 3SRQX 1AI9A 2FZJA 3NXRA 5E8QA 4H96A 5HSRA 3QL3A 5FDAA 5HT4A 3DAUA 1J3KA 1OHKA 2W9HA 3F8ZA 1MVSA 3KJSA 1RX3A 2O7PA 3E0BA 2BLAA 4I13A
chains in the Genus database with same CATH superfamily
3RG9A 3UM8A 4I1NA 4KNEA 4M2XA 4EIGA 4IXED 3JTWA 1RB3A 2HXVA 3QLRA 1RX4A 4CD2A 3EEJA 3FQ0A 3UM6A 3K74A 1S3VA 1RF7A 1MVTA 3TQAA 1DHIA 1DDRA 3L3RA 4M6KA 4G8ZX 3M09A 4XRBA 1DAJA 1TDRA 5U26A 2C2TA 4M6JA 3IRNA 5EAJA 1ZDRA 4QLEA 3D84X 1JOMA 4DPHA 5HVEA 3FQVA 3SA2A 2W9GA 1DHFA 2ZZAA 3FQFA 4QHVA 4GH8A 1DYHA 4QI9A 4Q0DA 3VCOA 1RA2A 4ECKA 3NXYA 3SRUX 5HI6A 3S9UA 3SA1A 1RC4A 1QZFA 1OHJA 1RX1A 3DRCA 1YHOA 2D5NA 4LAHX 3FL9A 3QG2A 1HFPA 5HSUA 3SRWX 1DRAA 2DHFA 3SAIA 1PD9A 4PSTA 2W3BA 3FYVX 3NZAX 3TQ9A 1LY3A 5HQZA 3JW3A 3DL6A 3FQCA 3HBBA 3QLZA 4QJCA 3QFXA 5HVBA 4KL9A 1M7AA 3NZ6X 1DR1A 1S3WA 2ANOA 2W3MA 3JWMA 3QYLA 3FRBX 2W3VA 4H97A 5HF0X 3NU0A 1DR6A 1KMSA 4ELBA 4FHBA 3IRMA 3Q1HA 4KEBA 1RE7A 3F0BX 1RX8A 1DRBA 4KY8A 3RO9A 3SR5X 5DXVA 1S3UA 1BOZA 1DISA 1IA2A 4Q67A 3GHCA 4PTHA 1RA8A 1RX9A 3SRRX 8DFRA 1U71A 4X5GA 5ECCA 1DRFA 4ELEA 3KFYA 1RD7A 3EEKA 1DLSA 2C2SA 2D0KA 4IXGX 3JWKA 4ELGA 4XT6A 4XE6X 4P68A 2B3ZA 1KLKA 1U72A 3FYWX 4HOFA 4IXFX 1DG5A 1U70A 1BZFA 1VDRA 4G95A 3F0UX 4KD7A 3NXVA 3S7AA 5CCCA 4G3MA 6DFRA 3NTZA 4M7VA 3GHVA 4KM0A 3DG8A 2BLBA 4NX7A 1LUDA 3F0XX 4M6LA 3NXXA 2GD9A 1RX5A 2ANQA 3K2HA 4QLGA 1DR5A 1RX2A 4XT7A 4KFJA 1D1GA 2W3AA 3TQ8A 3N0HA 4KYAA 4OR7A 3FY9X 2INQA 4EILA 1RX7A 2BLCA 2ITHA 4ELHA 3F0QX 5U27A 3ZPGA 4QJZD 1IA3A 3FL8A 1AOEA 3NZBX 1CD2A 3SGYA 3FQOA 4XT4A 3QLXA 2AZNA 4FGHA 2W3WA 1RG7A 1KMVA 5HF2X 4PDJA 1CZ3A 3KJRA 1RH3A 3TQBA 1VJ3A 3QLWA 4KLXA 5HPBA 4X5HA 2JYBA 4H98A 4KAKA 3KY8A 4KJKA 1M79A 3FY8X 2FZIA 3EELA 4Q6AA 3DFRA 3TD8A 1IA1A 4Q0EA 2OIPA 2CIGA 5JG0X 1RA9A 4FGGA 4TU5X 4KJJA 2KGKA 1DR4A 3I8AX 1IA4A 3FRAX 1DYRA 2XW7A 3EX8A 1DF7A 4ELFA 5JA3A 3UM5A 3FS6A 3CL9A 4QLFA 1PD8A 7DFRA 1DREA 3K47A 1M78A 4KM2A 1DYIA 3IA5A 3GI2A 3GHWA 4LAEX 1LY4A 3K45A 3I3RA 1RA1A 3EIGA 5CC9A 1RA3A 3IROA 3EEMA 3JVXA 1HFQA 2CD2A 3QL0A 1JOLA 3F0VX 3ROAA 4HOGA 2HM9A 4RGCA 4KBNA 3SQYX 4KY4A 4PSYA 3DATA 5ECXA 2P4GA 1J3JA 3QLYA 1DIUA 3S3VA 1DR3A 4X5FA 4LAGX 3SH2A 3NZDA 2DRCA 3JWFA 3INVA 3R33A 3OAFA 1DRHA 1DG7A 1SEJA 4HA7A 4M7UA 4P3RA 4H95A 3QLSA 4PSSA 2HQPA 3QYOA 1AO8A 2OBCA 1S3YA 3CSEA 1DR2A 3QGTA 4XECX 3CD2A 4X5JA 3ZPCA 1E26A 2G6VA 4DFRA 4KJLA 3NXOA 3HJ3A 2W9TA 3FRFX 4DPDA 5HT5A 3IX9A 4NX6A 1DG8A 1DDSA 3JSUA 3SRSX 3JWCA 3FREX 1DLRA 1HFRA 3FQZA 2FZHA 4DDRA 1PDBA 3DL5A 4EIZA 2BL9A 4HOEA 4PTJA 3NZCX 3OCHA 3LG4A 1J3IA 2H2QA 5HUIA 3F8YA 3JW5A 3CLBA 4XT8A 5HQYA 3F0SX 3NXTA 3D80A 1DHJA 3FRDX 3IA4A 2L28A 1DR7A 3DGAA 4HA9A 2LF1A 4X5IA 2W9SA 3M08A 1DYJA 4P3QA 1JUVA 4DP3A 2QK8A 3NZ9X 4XT5A 1RX6A 3NRRA 4OSGA 4LEKX 3GYFA 3F91A 1RB2A 4P66A 4EJ1A 5DFRA 3KGYA 3SRQX 1AI9A 2FZJA 3NXRA 5E8QA 4H96A 5HSRA 3QL3A 5FDAA 5HT4A 3DAUA 1J3KA 1OHKA 2W9HA 3F8ZA 1MVSA 3KJSA 1RX3A 2O7PA 3E0BA 2BLAA 4I13A
chains in the Genus database with same CATH topology
3RG9A 3UM8A 4I1NA 4KNEA 4M2XA 4EIGA 4IXED 3JTWA 1RB3A 2HXVA 3QLRA 1RX4A 4CD2A 3EEJA 3FQ0A 3UM6A 3K74A 1S3VA 1RF7A 1MVTA 3TQAA 1DHIA 1DDRA 3L3RA 4M6KA 4G8ZX 3M09A 4XRBA 1DAJA 1TDRA 5U26A 2C2TA 4M6JA 3IRNA 5EAJA 1ZDRA 4QLEA 3D84X 1JOMA 4DPHA 5HVEA 3FQVA 3SA2A 2W9GA 1DHFA 2ZZAA 3FQFA 4QHVA 4GH8A 1DYHA 4QI9A 4Q0DA 3VCOA 1RA2A 4ECKA 3NXYA 3SRUX 5HI6A 3S9UA 3SA1A 1RC4A 1QZFA 1OHJA 1RX1A 3DRCA 1YHOA 2D5NA 4LAHX 3FL9A 3QG2A 1HFPA 5HSUA 3SRWX 1DRAA 2DHFA 3SAIA 1PD9A 4PSTA 2W3BA 3FYVX 3NZAX 3TQ9A 1LY3A 5HQZA 3JW3A 3DL6A 3FQCA 3HBBA 3QLZA 4QJCA 3QFXA 5HVBA 4KL9A 1M7AA 3NZ6X 1DR1A 1S3WA 2ANOA 2W3MA 3JWMA 3QYLA 3FRBX 2W3VA 4H97A 5HF0X 3NU0A 1DR6A 1KMSA 4ELBA 4FHBA 3IRMA 3Q1HA 4KEBA 1RE7A 3F0BX 1RX8A 1DRBA 4KY8A 3RO9A 3SR5X 5DXVA 1S3UA 1BOZA 1DISA 1IA2A 4Q67A 3GHCA 4PTHA 1RA8A 1RX9A 3SRRX 8DFRA 1U71A 4X5GA 5ECCA 1DRFA 4ELEA 3KFYA 1RD7A 3EEKA 1DLSA 2C2SA 2D0KA 4IXGX 3JWKA 4ELGA 4XT6A 4XE6X 4P68A 2B3ZA 1KLKA 1U72A 3FYWX 4HOFA 4IXFX 1DG5A 1U70A 1BZFA 1VDRA 4G95A 3F0UX 4KD7A 3NXVA 3S7AA 5CCCA 4G3MA 6DFRA 3NTZA 4M7VA 3GHVA 4KM0A 3DG8A 2BLBA 4NX7A 1LUDA 3F0XX 4M6LA 3NXXA 2GD9A 1RX5A 2ANQA 3K2HA 4QLGA 1DR5A 1RX2A 4XT7A 4KFJA 1D1GA 2W3AA 3TQ8A 3N0HA 4KYAA 4OR7A 3FY9X 2INQA 4EILA 1RX7A 2BLCA 2ITHA 4ELHA 3F0QX 5U27A 3ZPGA 4QJZD 1IA3A 3FL8A 1AOEA 3NZBX 1CD2A 3SGYA 3FQOA 4XT4A 3QLXA 2AZNA 4FGHA 2W3WA 1RG7A 1KMVA 5HF2X 4PDJA 1CZ3A 3KJRA 1RH3A 3TQBA 1VJ3A 3QLWA 4KLXA 5HPBA 4X5HA 2JYBA 4H98A 4KAKA 3KY8A 4KJKA 1M79A 3FY8X 2FZIA 3EELA 4Q6AA 3DFRA 3TD8A 1IA1A 4Q0EA 2OIPA 2CIGA 5JG0X 1RA9A 4FGGA 4TU5X 4KJJA 2KGKA 1DR4A 3I8AX 1IA4A 3FRAX 1DYRA 2XW7A 3EX8A 1DF7A 4ELFA 5JA3A 3UM5A 3FS6A 3CL9A 4QLFA 1PD8A 7DFRA 1DREA 3K47A 1M78A 4KM2A 1DYIA 3IA5A 3GI2A 3GHWA 4LAEX 1LY4A 3K45A 3I3RA 1RA1A 3EIGA 5CC9A 1RA3A 3IROA 3EEMA 3JVXA 1HFQA 2CD2A 3QL0A 1JOLA 3F0VX 3ROAA 4HOGA 2HM9A 4RGCA 4KBNA 3SQYX 4KY4A 4PSYA 3DATA 5ECXA 2P4GA 1J3JA 3QLYA 1DIUA 3S3VA 1DR3A 4X5FA 4LAGX 3SH2A 3NZDA 2DRCA 3JWFA 3INVA 3R33A 3OAFA 1DRHA 1DG7A 1SEJA 4HA7A 4M7UA 4P3RA 4H95A 3QLSA 4PSSA 2HQPA 3QYOA 1AO8A 2OBCA 1S3YA 3CSEA 1DR2A 3QGTA 4XECX 3CD2A 4X5JA 3ZPCA 1E26A 2G6VA 4DFRA 4KJLA 3NXOA 3HJ3A 2W9TA 3FRFX 4DPDA 5HT5A 3IX9A 4NX6A 1DG8A 1DDSA 3JSUA 3SRSX 3JWCA 3FREX 1DLRA 1HFRA 3FQZA 2FZHA 4DDRA 1PDBA 3DL5A 4EIZA 2BL9A 4HOEA 4PTJA 3NZCX 3OCHA 3LG4A 1J3IA 2H2QA 5HUIA 3F8YA 3JW5A 3CLBA 4XT8A 5HQYA 3F0SX 3NXTA 3D80A 1DHJA 3FRDX 3IA4A 2L28A 1DR7A 3DGAA 4HA9A 2LF1A 4X5IA 2W9SA 3M08A 1DYJA 4P3QA 1JUVA 4DP3A 2QK8A 3NZ9X 4XT5A 1RX6A 3NRRA 4OSGA 4LEKX 3GYFA 3F91A 1RB2A 4P66A 4EJ1A 5DFRA 3KGYA 3SRQX 1AI9A 2FZJA 3NXRA 5E8QA 4H96A 5HSRA 3QL3A 5FDAA 5HT4A 3DAUA 1J3KA 1OHKA 2W9HA 3F8ZA 1MVSA 3KJSA 1RX3A 2O7PA 3E0BA 2BLAA 4I13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RG9 A;  3UM8 A;  4I1N A;  4KNE A;  4M2X A;  4EIG A;  4IXE D;  3JTW A;  1RB3 A;  2HXV A;  3QLR A;  1RX4 A;  4CD2 A;  3EEJ A;  3FQ0 A;  3UM6 A;  3K74 A;  1S3V A;  1RF7 A;  1MVT A;  3TQA A;  1DHI A;  1DDR A;  3L3R A;  4M6K A;  4G8Z X;  3M09 A;  4XRB A;  1DAJ A;  1TDR A;  5U26 A;  2C2T A;  4M6J A;  3IRN A;  5EAJ A;  1ZDR A;  4QLE A;  3D84 X;  1JOM A;  4DPH A;  5HVE A;  3FQV A;  3SA2 A;  2W9G A;  1DHF A;  2ZZA A;  3FQF A;  4QHV A;  4GH8 A;  1DYH A;  4QI9 A;  4Q0D A;  3VCO A;  1RA2 A;  4ECK A;  3NXY A;  3SRU X;  5HI6 A;  3S9U A;  3SA1 A;  1RC4 A;  1QZF A;  1OHJ A;  1RX1 A;  3DRC A;  1YHO A;  2D5N A;  4LAH X;  3FL9 A;  3QG2 A;  1HFP A;  5HSU A;  3SRW X;  1DRA A;  2DHF A;  3SAI A;  1PD9 A;  4PST A;  2W3B A;  3FYV X;  3NZA X;  3TQ9 A;  1LY3 A;  5HQZ A;  3JW3 A;  3DL6 A;  3FQC A;  3HBB A;  3QLZ A;  4QJC A;  3QFX A;  5HVB A;  4KL9 A;  1M7A A;  3NZ6 X;  1DR1 A;  1S3W A;  2ANO A;  2W3M A;  3JWM A;  3QYL A;  3FRB X;  2W3V A;  4H97 A;  5HF0 X;  3NU0 A;  1DR6 A;  1KMS A;  4ELB A;  4FHB A;  3IRM A;  3Q1H A;  4KEB A;  1RE7 A;  3F0B X;  1RX8 A;  1DRB A;  4KY8 A;  3RO9 A;  3SR5 X;  5DXV A;  1S3U A;  1BOZ A;  1DIS A;  1IA2 A;  4Q67 A;  3GHC A;  4PTH A;  1RA8 A;  1RX9 A;  3SRR X;  8DFR A;  1U71 A;  4X5G A;  5ECC A;  1DRF A;  4ELE A;  3KFY A;  1RD7 A;  3EEK A;  1DLS A;  2C2S A;  2D0K A;  4IXG X;  3JWK A;  4ELG A;  4XT6 A;  4XE6 X;  4P68 A;  2B3Z A;  1KLK A;  1U72 A;  3FYW X;  4HOF A;  4IXF X;  1DG5 A;  1U70 A;  1BZF A;  1VDR A;  4G95 A;  3F0U X;  4KD7 A;  3NXV A;  3S7A A;  5CCC A;  4G3M A;  6DFR A;  3NTZ A;  4M7V A;  3GHV A;  4KM0 A;  3DG8 A;  2BLB A;  4NX7 A;  1LUD A;  3F0X X;  4M6L A;  3NXX A;  2GD9 A;  1RX5 A;  2ANQ A;  3K2H A;  4QLG A;  1DR5 A;  1RX2 A;  4XT7 A;  4KFJ A;  1D1G A;  2W3A A;  3TQ8 A;  3N0H A;  4KYA A;  4OR7 A;  3FY9 X;  2INQ A;  4EIL A;  1RX7 A;  2BLC A;  2ITH A;  4ELH A;  3F0Q X;  5U27 A;  3ZPG A;  4QJZ D;  1IA3 A;  3FL8 A;  1AOE A;  3NZB X;  1CD2 A;  3SGY A;  3FQO A;  4XT4 A;  3QLX A;  2AZN A;  4FGH A;  2W3W A;  1RG7 A;  1KMV A;  5HF2 X;  4PDJ A;  1CZ3 A;  3KJR A;  1RH3 A;  3TQB A;  1VJ3 A;  3QLW A;  4KLX A;  5HPB A;  4X5H A;  2JYB A;  4H98 A;  4KAK A;  3KY8 A;  4KJK A;  1M79 A;  3FY8 X;  2FZI A;  3EEL A;  4Q6A A;  3DFR A;  3TD8 A;  1IA1 A;  4Q0E A;  2OIP A;  2CIG A;  5JG0 X;  1RA9 A;  4FGG A;  4TU5 X;  4KJJ A;  2KGK A;  1DR4 A;  3I8A X;  1IA4 A;  3FRA X;  1DYR A;  2XW7 A;  3EX8 A;  1DF7 A;  4ELF A;  5JA3 A;  3UM5 A;  3FS6 A;  3CL9 A;  4QLF A;  1PD8 A;  7DFR A;  1DRE A;  3K47 A;  1M78 A;  4KM2 A;  1DYI A;  3IA5 A;  3GI2 A;  3GHW A;  4LAE X;  1LY4 A;  3K45 A;  3I3R A;  1RA1 A;  3EIG A;  5CC9 A;  1RA3 A;  3IRO A;  3EEM A;  3JVX A;  1HFQ A;  2CD2 A;  3QL0 A;  1JOL A;  3F0V X;  3ROA A;  4HOG A;  2HM9 A;  4RGC A;  4KBN A;  3SQY X;  4KY4 A;  4PSY A;  3DAT A;  5ECX A;  2P4G A;  1J3J A;  3QLY A;  1DIU A;  3S3V A;  1DR3 A;  4X5F A;  4LAG X;  3SH2 A;  3NZD A;  2DRC A;  3JWF A;  3INV A;  3R33 A;  3OAF A;  1DRH A;  1DG7 A;  1SEJ A;  4HA7 A;  4M7U A;  4P3R A;  4H95 A;  3QLS A;  4PSS A;  2HQP A;  3QYO A;  1AO8 A;  2OBC A;  1S3Y A;  3CSE A;  1DR2 A;  3QGT A;  4XEC X;  3CD2 A;  4X5J A;  3ZPC A;  1E26 A;  2G6V A;  4DFR A;  4KJL A;  3NXO A;  3HJ3 A;  2W9T A;  3FRF X;  4DPD A;  5HT5 A;  3IX9 A;  4NX6 A;  1DG8 A;  1DDS A;  3JSU A;  3SRS X;  3JWC A;  3FRE X;  1DLR A;  1HFR A;  3FQZ A;  2FZH A;  4DDR A;  1PDB A;  3DL5 A;  4EIZ A;  2BL9 A;  4HOE A;  4PTJ A;  3NZC X;  3OCH A;  3LG4 A;  1J3I A;  2H2Q A;  5HUI A;  3F8Y A;  3JW5 A;  3CLB A;  4XT8 A;  5HQY A;  3F0S X;  3NXT A;  3D80 A;  1DHJ A;  3FRD X;  3IA4 A;  2L28 A;  1DR7 A;  3DGA A;  4HA9 A;  2LF1 A;  4X5I A;  2W9S A;  3M08 A;  1DYJ A;  4P3Q A;  1JUV A;  4DP3 A;  2QK8 A;  3NZ9 X;  4XT5 A;  1RX6 A;  3NRR A;  4OSG A;  4LEK X;  3GYF A;  3F91 A;  1RB2 A;  4P66 A;  4EJ1 A;  5DFR A;  3KGY A;  3SRQ X;  1AI9 A;  2FZJ A;  3NXR A;  5E8Q A;  4H96 A;  5HSR A;  3QL3 A;  5FDA A;  5HT4 A;  3DAU A;  1J3K A;  1OHK A;  2W9H A;  3F8Z A;  1MVS A;  3KJS A;  1RX3 A;  2O7P A;  3E0B A;  2BLA A;  4I13 A; 
#chains in the Genus database with same CATH topology
 3RG9 A;  3UM8 A;  4I1N A;  4KNE A;  4M2X A;  4EIG A;  4IXE D;  3JTW A;  1RB3 A;  2HXV A;  3QLR A;  1RX4 A;  4CD2 A;  3EEJ A;  3FQ0 A;  3UM6 A;  3K74 A;  1S3V A;  1RF7 A;  1MVT A;  3TQA A;  1DHI A;  1DDR A;  3L3R A;  4M6K A;  4G8Z X;  3M09 A;  4XRB A;  1DAJ A;  1TDR A;  5U26 A;  2C2T A;  4M6J A;  3IRN A;  5EAJ A;  1ZDR A;  4QLE A;  3D84 X;  1JOM A;  4DPH A;  5HVE A;  3FQV A;  3SA2 A;  2W9G A;  1DHF A;  2ZZA A;  3FQF A;  4QHV A;  4GH8 A;  1DYH A;  4QI9 A;  4Q0D A;  3VCO A;  1RA2 A;  4ECK A;  3NXY A;  3SRU X;  5HI6 A;  3S9U A;  3SA1 A;  1RC4 A;  1QZF A;  1OHJ A;  1RX1 A;  3DRC A;  1YHO A;  2D5N A;  4LAH X;  3FL9 A;  3QG2 A;  1HFP A;  5HSU A;  3SRW X;  1DRA A;  2DHF A;  3SAI A;  1PD9 A;  4PST A;  2W3B A;  3FYV X;  3NZA X;  3TQ9 A;  1LY3 A;  5HQZ A;  3JW3 A;  3DL6 A;  3FQC A;  3HBB A;  3QLZ A;  4QJC A;  3QFX A;  5HVB A;  4KL9 A;  1M7A A;  3NZ6 X;  1DR1 A;  1S3W A;  2ANO A;  2W3M A;  3JWM A;  3QYL A;  3FRB X;  2W3V A;  4H97 A;  5HF0 X;  3NU0 A;  1DR6 A;  1KMS A;  4ELB A;  4FHB A;  3IRM A;  3Q1H A;  4KEB A;  1RE7 A;  3F0B X;  1RX8 A;  1DRB A;  4KY8 A;  3RO9 A;  3SR5 X;  5DXV A;  1S3U A;  1BOZ A;  1DIS A;  1IA2 A;  4Q67 A;  3GHC A;  4PTH A;  1RA8 A;  1RX9 A;  3SRR X;  8DFR A;  1U71 A;  4X5G A;  5ECC A;  1DRF A;  4ELE A;  3KFY A;  1RD7 A;  3EEK A;  1DLS A;  2C2S A;  2D0K A;  4IXG X;  3JWK A;  4ELG A;  4XT6 A;  4XE6 X;  4P68 A;  2B3Z A;  1KLK A;  1U72 A;  3FYW X;  4HOF A;  4IXF X;  1DG5 A;  1U70 A;  1BZF A;  1VDR A;  4G95 A;  3F0U X;  4KD7 A;  3NXV A;  3S7A A;  5CCC A;  4G3M A;  6DFR A;  3NTZ A;  4M7V A;  3GHV A;  4KM0 A;  3DG8 A;  2BLB A;  4NX7 A;  1LUD A;  3F0X X;  4M6L A;  3NXX A;  2GD9 A;  1RX5 A;  2ANQ A;  3K2H A;  4QLG A;  1DR5 A;  1RX2 A;  4XT7 A;  4KFJ A;  1D1G A;  2W3A A;  3TQ8 A;  3N0H A;  4KYA A;  4OR7 A;  3FY9 X;  2INQ A;  4EIL A;  1RX7 A;  2BLC A;  2ITH A;  4ELH A;  3F0Q X;  5U27 A;  3ZPG A;  4QJZ D;  1IA3 A;  3FL8 A;  1AOE A;  3NZB X;  1CD2 A;  3SGY A;  3FQO A;  4XT4 A;  3QLX A;  2AZN A;  4FGH A;  2W3W A;  1RG7 A;  1KMV A;  5HF2 X;  4PDJ A;  1CZ3 A;  3KJR A;  1RH3 A;  3TQB A;  1VJ3 A;  3QLW A;  4KLX A;  5HPB A;  4X5H A;  2JYB A;  4H98 A;  4KAK A;  3KY8 A;  4KJK A;  1M79 A;  3FY8 X;  2FZI A;  3EEL A;  4Q6A A;  3DFR A;  3TD8 A;  1IA1 A;  4Q0E A;  2OIP A;  2CIG A;  5JG0 X;  1RA9 A;  4FGG A;  4TU5 X;  4KJJ A;  2KGK A;  1DR4 A;  3I8A X;  1IA4 A;  3FRA X;  1DYR A;  2XW7 A;  3EX8 A;  1DF7 A;  4ELF A;  5JA3 A;  3UM5 A;  3FS6 A;  3CL9 A;  4QLF A;  1PD8 A;  7DFR A;  1DRE A;  3K47 A;  1M78 A;  4KM2 A;  1DYI A;  3IA5 A;  3GI2 A;  3GHW A;  4LAE X;  1LY4 A;  3K45 A;  3I3R A;  1RA1 A;  3EIG A;  5CC9 A;  1RA3 A;  3IRO A;  3EEM A;  3JVX A;  1HFQ A;  2CD2 A;  3QL0 A;  1JOL A;  3F0V X;  3ROA A;  4HOG A;  2HM9 A;  4RGC A;  4KBN A;  3SQY X;  4KY4 A;  4PSY A;  3DAT A;  5ECX A;  2P4G A;  1J3J A;  3QLY A;  1DIU A;  3S3V A;  1DR3 A;  4X5F A;  4LAG X;  3SH2 A;  3NZD A;  2DRC A;  3JWF A;  3INV A;  3R33 A;  3OAF A;  1DRH A;  1DG7 A;  1SEJ A;  4HA7 A;  4M7U A;  4P3R A;  4H95 A;  3QLS A;  4PSS A;  2HQP A;  3QYO A;  1AO8 A;  2OBC A;  1S3Y A;  3CSE A;  1DR2 A;  3QGT A;  4XEC X;  3CD2 A;  4X5J A;  3ZPC A;  1E26 A;  2G6V A;  4DFR A;  4KJL A;  3NXO A;  3HJ3 A;  2W9T A;  3FRF X;  4DPD A;  5HT5 A;  3IX9 A;  4NX6 A;  1DG8 A;  1DDS A;  3JSU A;  3SRS X;  3JWC A;  3FRE X;  1DLR A;  1HFR A;  3FQZ A;  2FZH A;  4DDR A;  1PDB A;  3DL5 A;  4EIZ A;  2BL9 A;  4HOE A;  4PTJ A;  3NZC X;  3OCH A;  3LG4 A;  1J3I A;  2H2Q A;  5HUI A;  3F8Y A;  3JW5 A;  3CLB A;  4XT8 A;  5HQY A;  3F0S X;  3NXT A;  3D80 A;  1DHJ A;  3FRD X;  3IA4 A;  2L28 A;  1DR7 A;  3DGA A;  4HA9 A;  2LF1 A;  4X5I A;  2W9S A;  3M08 A;  1DYJ A;  4P3Q A;  1JUV A;  4DP3 A;  2QK8 A;  3NZ9 X;  4XT5 A;  1RX6 A;  3NRR A;  4OSG A;  4LEK X;  3GYF A;  3F91 A;  1RB2 A;  4P66 A;  4EJ1 A;  5DFR A;  3KGY A;  3SRQ X;  1AI9 A;  2FZJ A;  3NXR A;  5E8Q A;  4H96 A;  5HSR A;  3QL3 A;  5FDA A;  5HT4 A;  3DAU A;  1J3K A;  1OHK A;  2W9H A;  3F8Z A;  1MVS A;  3KJS A;  1RX3 A;  2O7P A;  3E0B A;  2BLA A;  4I13 A; 
#chains in the Genus database with same CATH homology
 3RG9 A;  3UM8 A;  4I1N A;  4KNE A;  4M2X A;  4EIG A;  4IXE D;  3JTW A;  1RB3 A;  2HXV A;  3QLR A;  1RX4 A;  4CD2 A;  3EEJ A;  3FQ0 A;  3UM6 A;  3K74 A;  1S3V A;  1RF7 A;  1MVT A;  3TQA A;  1DHI A;  1DDR A;  3L3R A;  4M6K A;  4G8Z X;  3M09 A;  4XRB A;  1DAJ A;  1TDR A;  5U26 A;  2C2T A;  4M6J A;  3IRN A;  5EAJ A;  1ZDR A;  4QLE A;  3D84 X;  1JOM A;  4DPH A;  5HVE A;  3FQV A;  3SA2 A;  2W9G A;  1DHF A;  2ZZA A;  3FQF A;  4QHV A;  4GH8 A;  1DYH A;  4QI9 A;  4Q0D A;  3VCO A;  1RA2 A;  4ECK A;  3NXY A;  3SRU X;  5HI6 A;  3S9U A;  3SA1 A;  1RC4 A;  1QZF A;  1OHJ A;  1RX1 A;  3DRC A;  1YHO A;  2D5N A;  4LAH X;  3FL9 A;  3QG2 A;  1HFP A;  5HSU A;  3SRW X;  1DRA A;  2DHF A;  3SAI A;  1PD9 A;  4PST A;  2W3B A;  3FYV X;  3NZA X;  3TQ9 A;  1LY3 A;  5HQZ A;  3JW3 A;  3DL6 A;  3FQC A;  3HBB A;  3QLZ A;  4QJC A;  3QFX A;  5HVB A;  4KL9 A;  1M7A A;  3NZ6 X;  1DR1 A;  1S3W A;  2ANO A;  2W3M A;  3JWM A;  3QYL A;  3FRB X;  2W3V A;  4H97 A;  5HF0 X;  3NU0 A;  1DR6 A;  1KMS A;  4ELB A;  4FHB A;  3IRM A;  3Q1H A;  4KEB A;  1RE7 A;  3F0B X;  1RX8 A;  1DRB A;  4KY8 A;  3RO9 A;  3SR5 X;  5DXV A;  1S3U A;  1BOZ A;  1DIS A;  1IA2 A;  4Q67 A;  3GHC A;  4PTH A;  1RA8 A;  1RX9 A;  3SRR X;  8DFR A;  1U71 A;  4X5G A;  5ECC A;  1DRF A;  4ELE A;  3KFY A;  1RD7 A;  3EEK A;  1DLS A;  2C2S A;  2D0K A;  4IXG X;  3JWK A;  4ELG A;  4XT6 A;  4XE6 X;  4P68 A;  2B3Z A;  1KLK A;  1U72 A;  3FYW X;  4HOF A;  4IXF X;  1DG5 A;  1U70 A;  1BZF A;  1VDR A;  4G95 A;  3F0U X;  4KD7 A;  3NXV A;  3S7A A;  5CCC A;  4G3M A;  6DFR A;  3NTZ A;  4M7V A;  3GHV A;  4KM0 A;  3DG8 A;  2BLB A;  4NX7 A;  1LUD A;  3F0X X;  4M6L A;  3NXX A;  2GD9 A;  1RX5 A;  2ANQ A;  3K2H A;  4QLG A;  1DR5 A;  1RX2 A;  4XT7 A;  4KFJ A;  1D1G A;  2W3A A;  3TQ8 A;  3N0H A;  4KYA A;  4OR7 A;  3FY9 X;  2INQ A;  4EIL A;  1RX7 A;  2BLC A;  2ITH A;  4ELH A;  3F0Q X;  5U27 A;  3ZPG A;  4QJZ D;  1IA3 A;  3FL8 A;  1AOE A;  3NZB X;  1CD2 A;  3SGY A;  3FQO A;  4XT4 A;  3QLX A;  2AZN A;  4FGH A;  2W3W A;  1RG7 A;  1KMV A;  5HF2 X;  4PDJ A;  1CZ3 A;  3KJR A;  1RH3 A;  3TQB A;  1VJ3 A;  3QLW A;  4KLX A;  5HPB A;  4X5H A;  2JYB A;  4H98 A;  4KAK A;  3KY8 A;  4KJK A;  1M79 A;  3FY8 X;  2FZI A;  3EEL A;  4Q6A A;  3DFR A;  3TD8 A;  1IA1 A;  4Q0E A;  2OIP A;  2CIG A;  5JG0 X;  1RA9 A;  4FGG A;  4TU5 X;  4KJJ A;  2KGK A;  1DR4 A;  3I8A X;  1IA4 A;  3FRA X;  1DYR A;  2XW7 A;  3EX8 A;  1DF7 A;  4ELF A;  5JA3 A;  3UM5 A;  3FS6 A;  3CL9 A;  4QLF A;  1PD8 A;  7DFR A;  1DRE A;  3K47 A;  1M78 A;  4KM2 A;  1DYI A;  3IA5 A;  3GI2 A;  3GHW A;  4LAE X;  1LY4 A;  3K45 A;  3I3R A;  1RA1 A;  3EIG A;  5CC9 A;  1RA3 A;  3IRO A;  3EEM A;  3JVX A;  1HFQ A;  2CD2 A;  3QL0 A;  1JOL A;  3F0V X;  3ROA A;  4HOG A;  2HM9 A;  4RGC A;  4KBN A;  3SQY X;  4KY4 A;  4PSY A;  3DAT A;  5ECX A;  2P4G A;  1J3J A;  3QLY A;  1DIU A;  3S3V A;  1DR3 A;  4X5F A;  4LAG X;  3SH2 A;  3NZD A;  2DRC A;  3JWF A;  3INV A;  3R33 A;  3OAF A;  1DRH A;  1DG7 A;  1SEJ A;  4HA7 A;  4M7U A;  4P3R A;  4H95 A;  3QLS A;  4PSS A;  2HQP A;  3QYO A;  1AO8 A;  2OBC A;  1S3Y A;  3CSE A;  1DR2 A;  3QGT A;  4XEC X;  3CD2 A;  4X5J A;  3ZPC A;  1E26 A;  2G6V A;  4DFR A;  4KJL A;  3NXO A;  3HJ3 A;  2W9T A;  3FRF X;  4DPD A;  5HT5 A;  3IX9 A;  4NX6 A;  1DG8 A;  1DDS A;  3JSU A;  3SRS X;  3JWC A;  3FRE X;  1DLR A;  1HFR A;  3FQZ A;  2FZH A;  4DDR A;  1PDB A;  3DL5 A;  4EIZ A;  2BL9 A;  4HOE A;  4PTJ A;  3NZC X;  3OCH A;  3LG4 A;  1J3I A;  2H2Q A;  5HUI A;  3F8Y A;  3JW5 A;  3CLB A;  4XT8 A;  5HQY A;  3F0S X;  3NXT A;  3D80 A;  1DHJ A;  3FRD X;  3IA4 A;  2L28 A;  1DR7 A;  3DGA A;  4HA9 A;  2LF1 A;  4X5I A;  2W9S A;  3M08 A;  1DYJ A;  4P3Q A;  1JUV A;  4DP3 A;  2QK8 A;  3NZ9 X;  4XT5 A;  1RX6 A;  3NRR A;  4OSG A;  4LEK X;  3GYF A;  3F91 A;  1RB2 A;  4P66 A;  4EJ1 A;  5DFR A;  3KGY A;  3SRQ X;  1AI9 A;  2FZJ A;  3NXR A;  5E8Q A;  4H96 A;  5HSR A;  3QL3 A;  5FDA A;  5HT4 A;  3DAU A;  1J3K A;  1OHK A;  2W9H A;  3F8Z A;  1MVS A;  3KJS A;  1RX3 A;  2O7P A;  3E0B A;  2BLA A;  4I13 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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