3JWCA

Crystal structure of bacillus anthracis (y102f) dihydrofolate reductase complexed with nadph and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (ucp120a)
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
165
structure length
165
Chain Sequence
HHHMRVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIFDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeted Mutations in Bacillus anthracis Dihydrofolate Reductase Condense Complex Structure-Activity Relationships
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Bacillus anthracis
molecule keywords Dihydrofolate reductase
total genus 44
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3jwcA00
1HFPA 4Q0EA 4I13A 2W9GA 3FQVA 3OCHA 5HVEA 3EELA 1RA2A 4DFRA 3SRRX 1IA1A 1DRFA 1DHFA 2BLAA 3DRCA 4QI9A 1PD9A 4HOEA 4HA9A 4KJKA 3E0BA 3FL9A 3DFRA 2ITHA 2BL9A 3IRMA 5U27A 1RC4A 2XW7A 4QLEA 2JYBA 5HT5A 5HQZA 1DR7A 1BOZA 2KGKA 2W3VA 4X5IA 2OBCA 3IA4A 4P68A 3R33A 2DHFA 3F0UX 3EX8A 2FZIA 4KM2A 3F8YA 3F0QX 5EAJA 1RB2A 4KBNA 4KL9A 5U26A 3TQ8A 4Q0DA 3CSEA 2CIGA 1RX9A 3JTWA 1QZFA 3NZDA 6DFRA 1SEJA 3FQOA 4KFJA 3EEKA 3FYWX 4KYAA 1U72A 3K2HA 4ELFA 4XECX 1RX1A 4I1NA 2ZZAA 1MVSA 4X5GA 4IXGX 4X5HA 2W3WA 3NZAX 3S7AA 1CZ3A 4ELBA 3JVXA 5JA3A 3D84X 1LUDA 3DL6A 2BLBA 4IXED 1DR3A 4XT5A 1IA2A 5JG0X 4EIZA 3QLSA 3QLZA 5HF2X 4FHBA 4PSYA 3RO9A 1LY4A 3UM5A 3SAIA 3DG8A 3EEJA 5HF0X 3KFYA 4DPHA 3JWMA 4DDRA 1YHOA 2W3AA 1DLRA 3DGAA 2W9TA 2INQA 1J3JA 3GHWA 4M6JA 5DXVA 3SGYA 4Q67A 1DRAA 3DATA 4HA7A 1PD8A 3F8ZA 4FGGA 5HUIA 1J3KA 4M2XA 3OAFA 4XE6X 1OHJA 4NX7A 4PDJA 3ZPCA 1DLSA 5HSRA 3SA1A 4KD7A 2D0KA 1ZDRA 2C2TA 1DR1A 3NXXA 3TQ9A 2BLCA 3FQZA 1OHKA 3HJ3A 4KNEA 1RA1A 3GYFA 1DHIA 1S3YA 5E8QA 2HM9A 4M6LA 3FREX 4X5JA 3IA5A 4H97A 2OIPA 3SRQX 1RX8A 3GI2A 3JWCA 3FYVX 1TDRA 3NZ9X 4XRBA 1KMSA 2G6VA 1BZFA 4LAHX 5ECXA 4H98A 3IX9A 2QK8A 4XT6A 4G95A 1RX5A 5HQYA 4EJ1A 2W9HA 2FZJA 2W3BA 1DDRA 3Q1HA 3IROA 3K45A 4H95A 3KJSA 2LF1A 3F0XX 4M6KA 4GH8A 1RA8A 4ELHA 1DIUA 4PTJA 1D1GA 3DL5A 1RB3A 4M7UA 2AZNA 3HBBA 3NXYA 1DHJA 7DFRA 5CC9A 1M78A 3KY8A 4PSSA 3NXOA 3SH2A 3QLWA 1HFRA 4HOGA 4CD2A 3NXVA 1DDSA 4HOFA 3K74A 4P3QA 4KAKA 3JWFA 4G8ZX 4KM0A 1U71A 1RD7A 3UM6A 1AOEA 3NZCX 1RA3A 1JOLA 3NRRA 4Q6AA 3I3RA 5CCCA 3TQBA 1DYJA 1J3IA 3FQ0A 4ELEA 1RX4A 1M7AA 1RE7A 1M79A 3NXRA 1DRHA 5ECCA 4QJZD 2HXVA 3QLYA 3F0SX 3ZPGA 3S9UA 1RH3A 4DP3A 2DRCA 2GD9A 2P4GA 4QLGA 1DR5A 3INVA 3NZBX 3CL9A 3RG9A 3LG4A 3FRDX 2O7PA 4LAGX 2D5NA 3TD8A 2B3ZA 3TQAA 3FQFA 2W3MA 4LAEX 3FL8A 4PSTA 3I8AX 3KGYA 1RA9A 4LEKX 3D80A 1VDRA 4RGCA 2ANQA 3QGTA 3UM8A 3QFXA 4NX6A 3SRSX 3N0HA 4XT4A 3EIGA 1CD2A 4KY8A 4X5FA 1HFQA 1VJ3A 5HT4A 3FY9X 3FRFX 3F0BX 3QL3A 5FDAA 3CLBA 4P66A 1PDBA 3FRBX 3CD2A 4KJLA 3S3VA 1DRBA 1RX2A 1RG7A 2CD2A 1DR2A 3KJRA 1DYIA 3QYOA 1DYHA 4OR7A 3JW3A 5DFRA 1KLKA 3JWKA 2W9SA 5HSUA 4P3RA 4FGHA 3QYLA 4DPDA 3NU0A 2L28A 3F0VX 4OSGA 4KLXA 1AI9A 3K47A 3QL0A 1DF7A 4IXFX 1RX7A 3M09A 1LY3A 4KEBA 2C2SA 1KMVA 4XT7A 5HPBA 1DG8A 3SR5X 4EILA 4KY4A 3L3RA 4QJCA 3GHCA 1S3WA 1IA3A 4QHVA 2FZHA 2ANOA 3DAUA 1DG7A 4EIGA 3QLXA 3JSUA 3NZ6X 1RX6A 3FQCA 1JUVA 4XT8A 1S3VA 1DYRA 3NXTA 3SQYX 1IA4A 1DR4A 1RF7A 3M08A 1DREA 4ELGA 1U70A 1S3UA 4ECKA 1DG5A 3FS6A 3FRAX 2HQPA 3SRWX 4G3MA 4QLFA 1DAJA 5HI6A 3EEMA 4PTHA 3F91A 1JOMA 1E26A 3SA2A 3JW5A 3IRNA 5HVBA 4KJJA 4M7VA 3QLRA 1DISA 2H2QA 3NTZA 3SRUX 3VCOA 1MVTA 3ROAA 3GHVA 1DR6A 1RX3A 4H96A 4TU5X 8DFRA 3FY8X 1AO8A 3QG2A
chains in the Genus database with same CATH superfamily
1HFPA 4Q0EA 4I13A 2W9GA 3FQVA 3OCHA 5HVEA 3EELA 1RA2A 4DFRA 3SRRX 1IA1A 1DRFA 1DHFA 2BLAA 3DRCA 4QI9A 1PD9A 4HOEA 4HA9A 4KJKA 3E0BA 3FL9A 3DFRA 2ITHA 2BL9A 3IRMA 5U27A 1RC4A 2XW7A 4QLEA 2JYBA 5HT5A 5HQZA 1DR7A 1BOZA 2KGKA 2W3VA 4X5IA 2OBCA 3IA4A 4P68A 3R33A 2DHFA 3F0UX 3EX8A 2FZIA 4KM2A 3F8YA 3F0QX 5EAJA 1RB2A 4KBNA 4KL9A 5U26A 3TQ8A 4Q0DA 3CSEA 2CIGA 1RX9A 3JTWA 1QZFA 3NZDA 6DFRA 1SEJA 3FQOA 4KFJA 3EEKA 3FYWX 4KYAA 1U72A 3K2HA 4ELFA 4XECX 1RX1A 4I1NA 2ZZAA 1MVSA 4X5GA 4IXGX 4X5HA 2W3WA 3NZAX 3S7AA 1CZ3A 4ELBA 3JVXA 5JA3A 3D84X 1LUDA 3DL6A 2BLBA 4IXED 1DR3A 4XT5A 1IA2A 5JG0X 4EIZA 3QLSA 3QLZA 5HF2X 4FHBA 4PSYA 3RO9A 1LY4A 3UM5A 3SAIA 3DG8A 3EEJA 5HF0X 3KFYA 4DPHA 3JWMA 4DDRA 1YHOA 2W3AA 1DLRA 3DGAA 2W9TA 2INQA 1J3JA 3GHWA 4M6JA 5DXVA 3SGYA 4Q67A 1DRAA 3DATA 4HA7A 1PD8A 3F8ZA 4FGGA 5HUIA 1J3KA 4M2XA 3OAFA 4XE6X 1OHJA 4NX7A 4PDJA 3ZPCA 1DLSA 5HSRA 3SA1A 4KD7A 2D0KA 1ZDRA 2C2TA 1DR1A 3NXXA 3TQ9A 2BLCA 3FQZA 1OHKA 3HJ3A 4KNEA 1RA1A 3GYFA 1DHIA 1S3YA 5E8QA 2HM9A 4M6LA 3FREX 4X5JA 3IA5A 4H97A 2OIPA 3SRQX 1RX8A 3GI2A 3JWCA 3FYVX 1TDRA 3NZ9X 4XRBA 1KMSA 2G6VA 1BZFA 4LAHX 5ECXA 4H98A 3IX9A 2QK8A 4XT6A 4G95A 1RX5A 5HQYA 4EJ1A 2W9HA 2FZJA 2W3BA 1DDRA 3Q1HA 3IROA 3K45A 4H95A 3KJSA 2LF1A 3F0XX 4M6KA 4GH8A 1RA8A 4ELHA 1DIUA 4PTJA 1D1GA 3DL5A 1RB3A 4M7UA 2AZNA 3HBBA 3NXYA 1DHJA 7DFRA 5CC9A 1M78A 3KY8A 4PSSA 3NXOA 3SH2A 3QLWA 1HFRA 4HOGA 4CD2A 3NXVA 1DDSA 4HOFA 3K74A 4P3QA 4KAKA 3JWFA 4G8ZX 4KM0A 1U71A 1RD7A 3UM6A 1AOEA 3NZCX 1RA3A 1JOLA 3NRRA 4Q6AA 3I3RA 5CCCA 3TQBA 1DYJA 1J3IA 3FQ0A 4ELEA 1RX4A 1M7AA 1RE7A 1M79A 3NXRA 1DRHA 5ECCA 4QJZD 2HXVA 3QLYA 3F0SX 3ZPGA 3S9UA 1RH3A 4DP3A 2DRCA 2GD9A 2P4GA 4QLGA 1DR5A 3INVA 3NZBX 3CL9A 3RG9A 3LG4A 3FRDX 2O7PA 4LAGX 2D5NA 3TD8A 2B3ZA 3TQAA 3FQFA 2W3MA 4LAEX 3FL8A 4PSTA 3I8AX 3KGYA 1RA9A 4LEKX 3D80A 1VDRA 4RGCA 2ANQA 3QGTA 3UM8A 3QFXA 4NX6A 3SRSX 3N0HA 4XT4A 3EIGA 1CD2A 4KY8A 4X5FA 1HFQA 1VJ3A 5HT4A 3FY9X 3FRFX 3F0BX 3QL3A 5FDAA 3CLBA 4P66A 1PDBA 3FRBX 3CD2A 4KJLA 3S3VA 1DRBA 1RX2A 1RG7A 2CD2A 1DR2A 3KJRA 1DYIA 3QYOA 1DYHA 4OR7A 3JW3A 5DFRA 1KLKA 3JWKA 2W9SA 5HSUA 4P3RA 4FGHA 3QYLA 4DPDA 3NU0A 2L28A 3F0VX 4OSGA 4KLXA 1AI9A 3K47A 3QL0A 1DF7A 4IXFX 1RX7A 3M09A 1LY3A 4KEBA 2C2SA 1KMVA 4XT7A 5HPBA 1DG8A 3SR5X 4EILA 4KY4A 3L3RA 4QJCA 3GHCA 1S3WA 1IA3A 4QHVA 2FZHA 2ANOA 3DAUA 1DG7A 4EIGA 3QLXA 3JSUA 3NZ6X 1RX6A 3FQCA 1JUVA 4XT8A 1S3VA 1DYRA 3NXTA 3SQYX 1IA4A 1DR4A 1RF7A 3M08A 1DREA 4ELGA 1U70A 1S3UA 4ECKA 1DG5A 3FS6A 3FRAX 2HQPA 3SRWX 4G3MA 4QLFA 1DAJA 5HI6A 3EEMA 4PTHA 3F91A 1JOMA 1E26A 3SA2A 3JW5A 3IRNA 5HVBA 4KJJA 4M7VA 3QLRA 1DISA 2H2QA 3NTZA 3SRUX 3VCOA 1MVTA 3ROAA 3GHVA 1DR6A 1RX3A 4H96A 4TU5X 8DFRA 3FY8X 1AO8A 3QG2A
chains in the Genus database with same CATH topology
1HFPA 4Q0EA 4I13A 2W9GA 3FQVA 3OCHA 5HVEA 3EELA 1RA2A 4DFRA 3SRRX 1IA1A 1DRFA 1DHFA 2BLAA 3DRCA 4QI9A 1PD9A 4HOEA 4HA9A 4KJKA 3E0BA 3FL9A 3DFRA 2ITHA 2BL9A 3IRMA 5U27A 1RC4A 2XW7A 4QLEA 2JYBA 5HT5A 5HQZA 1DR7A 1BOZA 2KGKA 2W3VA 4X5IA 2OBCA 3IA4A 4P68A 3R33A 2DHFA 3F0UX 3EX8A 2FZIA 4KM2A 3F8YA 3F0QX 5EAJA 1RB2A 4KBNA 4KL9A 5U26A 3TQ8A 4Q0DA 3CSEA 2CIGA 1RX9A 3JTWA 1QZFA 3NZDA 6DFRA 1SEJA 3FQOA 4KFJA 3EEKA 3FYWX 4KYAA 1U72A 3K2HA 4ELFA 4XECX 1RX1A 4I1NA 2ZZAA 1MVSA 4X5GA 4IXGX 4X5HA 2W3WA 3NZAX 3S7AA 1CZ3A 4ELBA 3JVXA 5JA3A 3D84X 1LUDA 3DL6A 2BLBA 4IXED 1DR3A 4XT5A 1IA2A 5JG0X 4EIZA 3QLSA 3QLZA 5HF2X 4FHBA 4PSYA 3RO9A 1LY4A 3UM5A 3SAIA 3DG8A 3EEJA 5HF0X 3KFYA 4DPHA 3JWMA 4DDRA 1YHOA 2W3AA 1DLRA 3DGAA 2W9TA 2INQA 1J3JA 3GHWA 4M6JA 5DXVA 3SGYA 4Q67A 1DRAA 3DATA 4HA7A 1PD8A 3F8ZA 4FGGA 5HUIA 1J3KA 4M2XA 3OAFA 4XE6X 1OHJA 4NX7A 4PDJA 3ZPCA 1DLSA 5HSRA 3SA1A 4KD7A 2D0KA 1ZDRA 2C2TA 1DR1A 3NXXA 3TQ9A 2BLCA 3FQZA 1OHKA 3HJ3A 4KNEA 1RA1A 3GYFA 1DHIA 1S3YA 5E8QA 2HM9A 4M6LA 3FREX 4X5JA 3IA5A 4H97A 2OIPA 3SRQX 1RX8A 3GI2A 3JWCA 3FYVX 1TDRA 3NZ9X 4XRBA 1KMSA 2G6VA 1BZFA 4LAHX 5ECXA 4H98A 3IX9A 2QK8A 4XT6A 4G95A 1RX5A 5HQYA 4EJ1A 2W9HA 2FZJA 2W3BA 1DDRA 3Q1HA 3IROA 3K45A 4H95A 3KJSA 2LF1A 3F0XX 4M6KA 4GH8A 1RA8A 4ELHA 1DIUA 4PTJA 1D1GA 3DL5A 1RB3A 4M7UA 2AZNA 3HBBA 3NXYA 1DHJA 7DFRA 5CC9A 1M78A 3KY8A 4PSSA 3NXOA 3SH2A 3QLWA 1HFRA 4HOGA 4CD2A 3NXVA 1DDSA 4HOFA 3K74A 4P3QA 4KAKA 3JWFA 4G8ZX 4KM0A 1U71A 1RD7A 3UM6A 1AOEA 3NZCX 1RA3A 1JOLA 3NRRA 4Q6AA 3I3RA 5CCCA 3TQBA 1DYJA 1J3IA 3FQ0A 4ELEA 1RX4A 1M7AA 1RE7A 1M79A 3NXRA 1DRHA 5ECCA 4QJZD 2HXVA 3QLYA 3F0SX 3ZPGA 3S9UA 1RH3A 4DP3A 2DRCA 2GD9A 2P4GA 4QLGA 1DR5A 3INVA 3NZBX 3CL9A 3RG9A 3LG4A 3FRDX 2O7PA 4LAGX 2D5NA 3TD8A 2B3ZA 3TQAA 3FQFA 2W3MA 4LAEX 3FL8A 4PSTA 3I8AX 3KGYA 1RA9A 4LEKX 3D80A 1VDRA 4RGCA 2ANQA 3QGTA 3UM8A 3QFXA 4NX6A 3SRSX 3N0HA 4XT4A 3EIGA 1CD2A 4KY8A 4X5FA 1HFQA 1VJ3A 5HT4A 3FY9X 3FRFX 3F0BX 3QL3A 5FDAA 3CLBA 4P66A 1PDBA 3FRBX 3CD2A 4KJLA 3S3VA 1DRBA 1RX2A 1RG7A 2CD2A 1DR2A 3KJRA 1DYIA 3QYOA 1DYHA 4OR7A 3JW3A 5DFRA 1KLKA 3JWKA 2W9SA 5HSUA 4P3RA 4FGHA 3QYLA 4DPDA 3NU0A 2L28A 3F0VX 4OSGA 4KLXA 1AI9A 3K47A 3QL0A 1DF7A 4IXFX 1RX7A 3M09A 1LY3A 4KEBA 2C2SA 1KMVA 4XT7A 5HPBA 1DG8A 3SR5X 4EILA 4KY4A 3L3RA 4QJCA 3GHCA 1S3WA 1IA3A 4QHVA 2FZHA 2ANOA 3DAUA 1DG7A 4EIGA 3QLXA 3JSUA 3NZ6X 1RX6A 3FQCA 1JUVA 4XT8A 1S3VA 1DYRA 3NXTA 3SQYX 1IA4A 1DR4A 1RF7A 3M08A 1DREA 4ELGA 1U70A 1S3UA 4ECKA 1DG5A 3FS6A 3FRAX 2HQPA 3SRWX 4G3MA 4QLFA 1DAJA 5HI6A 3EEMA 4PTHA 3F91A 1JOMA 1E26A 3SA2A 3JW5A 3IRNA 5HVBA 4KJJA 4M7VA 3QLRA 1DISA 2H2QA 3NTZA 3SRUX 3VCOA 1MVTA 3ROAA 3GHVA 1DR6A 1RX3A 4H96A 4TU5X 8DFRA 3FY8X 1AO8A 3QG2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HFP A;  4Q0E A;  4I13 A;  2W9G A;  3FQV A;  3OCH A;  5HVE A;  3EEL A;  1RA2 A;  4DFR A;  3SRR X;  1IA1 A;  1DRF A;  1DHF A;  2BLA A;  3DRC A;  4QI9 A;  1PD9 A;  4HOE A;  4HA9 A;  4KJK A;  3E0B A;  3FL9 A;  3DFR A;  2ITH A;  2BL9 A;  3IRM A;  5U27 A;  1RC4 A;  2XW7 A;  4QLE A;  2JYB A;  5HT5 A;  5HQZ A;  1DR7 A;  1BOZ A;  2KGK A;  2W3V A;  4X5I A;  2OBC A;  3IA4 A;  4P68 A;  3R33 A;  2DHF A;  3F0U X;  3EX8 A;  2FZI A;  4KM2 A;  3F8Y A;  3F0Q X;  5EAJ A;  1RB2 A;  4KBN A;  4KL9 A;  5U26 A;  3TQ8 A;  4Q0D A;  3CSE A;  2CIG A;  1RX9 A;  3JTW A;  1QZF A;  3NZD A;  6DFR A;  1SEJ A;  3FQO A;  4KFJ A;  3EEK A;  3FYW X;  4KYA A;  1U72 A;  3K2H A;  4ELF A;  4XEC X;  1RX1 A;  4I1N A;  2ZZA A;  1MVS A;  4X5G A;  4IXG X;  4X5H A;  2W3W A;  3NZA X;  3S7A A;  1CZ3 A;  4ELB A;  3JVX A;  5JA3 A;  3D84 X;  1LUD A;  3DL6 A;  2BLB A;  4IXE D;  1DR3 A;  4XT5 A;  1IA2 A;  5JG0 X;  4EIZ A;  3QLS A;  3QLZ A;  5HF2 X;  4FHB A;  4PSY A;  3RO9 A;  1LY4 A;  3UM5 A;  3SAI A;  3DG8 A;  3EEJ A;  5HF0 X;  3KFY A;  4DPH A;  3JWM A;  4DDR A;  1YHO A;  2W3A A;  1DLR A;  3DGA A;  2W9T A;  2INQ A;  1J3J A;  3GHW A;  4M6J A;  5DXV A;  3SGY A;  4Q67 A;  1DRA A;  3DAT A;  4HA7 A;  1PD8 A;  3F8Z A;  4FGG A;  5HUI A;  1J3K A;  4M2X A;  3OAF A;  4XE6 X;  1OHJ A;  4NX7 A;  4PDJ A;  3ZPC A;  1DLS A;  5HSR A;  3SA1 A;  4KD7 A;  2D0K A;  1ZDR A;  2C2T A;  1DR1 A;  3NXX A;  3TQ9 A;  2BLC A;  3FQZ A;  1OHK A;  3HJ3 A;  4KNE A;  1RA1 A;  3GYF A;  1DHI A;  1S3Y A;  5E8Q A;  2HM9 A;  4M6L A;  3FRE X;  4X5J A;  3IA5 A;  4H97 A;  2OIP A;  3SRQ X;  1RX8 A;  3GI2 A;  3JWC A;  3FYV X;  1TDR A;  3NZ9 X;  4XRB A;  1KMS A;  2G6V A;  1BZF A;  4LAH X;  5ECX A;  4H98 A;  3IX9 A;  2QK8 A;  4XT6 A;  4G95 A;  1RX5 A;  5HQY A;  4EJ1 A;  2W9H A;  2FZJ A;  2W3B A;  1DDR A;  3Q1H A;  3IRO A;  3K45 A;  4H95 A;  3KJS A;  2LF1 A;  3F0X X;  4M6K A;  4GH8 A;  1RA8 A;  4ELH A;  1DIU A;  4PTJ A;  1D1G A;  3DL5 A;  1RB3 A;  4M7U A;  2AZN A;  3HBB A;  3NXY A;  1DHJ A;  7DFR A;  5CC9 A;  1M78 A;  3KY8 A;  4PSS A;  3NXO A;  3SH2 A;  3QLW A;  1HFR A;  4HOG A;  4CD2 A;  3NXV A;  1DDS A;  4HOF A;  3K74 A;  4P3Q A;  4KAK A;  3JWF A;  4G8Z X;  4KM0 A;  1U71 A;  1RD7 A;  3UM6 A;  1AOE A;  3NZC X;  1RA3 A;  1JOL A;  3NRR A;  4Q6A A;  3I3R A;  5CCC A;  3TQB A;  1DYJ A;  1J3I A;  3FQ0 A;  4ELE A;  1RX4 A;  1M7A A;  1RE7 A;  1M79 A;  3NXR A;  1DRH A;  5ECC A;  4QJZ D;  2HXV A;  3QLY A;  3F0S X;  3ZPG A;  3S9U A;  1RH3 A;  4DP3 A;  2DRC A;  2GD9 A;  2P4G A;  4QLG A;  1DR5 A;  3INV A;  3NZB X;  3CL9 A;  3RG9 A;  3LG4 A;  3FRD X;  2O7P A;  4LAG X;  2D5N A;  3TD8 A;  2B3Z A;  3TQA A;  3FQF A;  2W3M A;  4LAE X;  3FL8 A;  4PST A;  3I8A X;  3KGY A;  1RA9 A;  4LEK X;  3D80 A;  1VDR A;  4RGC A;  2ANQ A;  3QGT A;  3UM8 A;  3QFX A;  4NX6 A;  3SRS X;  3N0H A;  4XT4 A;  3EIG A;  1CD2 A;  4KY8 A;  4X5F A;  1HFQ A;  1VJ3 A;  5HT4 A;  3FY9 X;  3FRF X;  3F0B X;  3QL3 A;  5FDA A;  3CLB A;  4P66 A;  1PDB A;  3FRB X;  3CD2 A;  4KJL A;  3S3V A;  1DRB A;  1RX2 A;  1RG7 A;  2CD2 A;  1DR2 A;  3KJR A;  1DYI A;  3QYO A;  1DYH A;  4OR7 A;  3JW3 A;  5DFR A;  1KLK A;  3JWK A;  2W9S A;  5HSU A;  4P3R A;  4FGH A;  3QYL A;  4DPD A;  3NU0 A;  2L28 A;  3F0V X;  4OSG A;  4KLX A;  1AI9 A;  3K47 A;  3QL0 A;  1DF7 A;  4IXF X;  1RX7 A;  3M09 A;  1LY3 A;  4KEB A;  2C2S A;  1KMV A;  4XT7 A;  5HPB A;  1DG8 A;  3SR5 X;  4EIL A;  4KY4 A;  3L3R A;  4QJC A;  3GHC A;  1S3W A;  1IA3 A;  4QHV A;  2FZH A;  2ANO A;  3DAU A;  1DG7 A;  4EIG A;  3QLX A;  3JSU A;  3NZ6 X;  1RX6 A;  3FQC A;  1JUV A;  4XT8 A;  1S3V A;  1DYR A;  3NXT A;  3SQY X;  1IA4 A;  1DR4 A;  1RF7 A;  3M08 A;  1DRE A;  4ELG A;  1U70 A;  1S3U A;  4ECK A;  1DG5 A;  3FS6 A;  3FRA X;  2HQP A;  3SRW X;  4G3M A;  4QLF A;  1DAJ A;  5HI6 A;  3EEM A;  4PTH A;  3F91 A;  1JOM A;  1E26 A;  3SA2 A;  3JW5 A;  3IRN A;  5HVB A;  4KJJ A;  4M7V A;  3QLR A;  1DIS A;  2H2Q A;  3NTZ A;  3SRU X;  3VCO A;  1MVT A;  3ROA A;  3GHV A;  1DR6 A;  1RX3 A;  4H96 A;  4TU5 X;  8DFR A;  3FY8 X;  1AO8 A;  3QG2 A; 
#chains in the Genus database with same CATH topology
 1HFP A;  4Q0E A;  4I13 A;  2W9G A;  3FQV A;  3OCH A;  5HVE A;  3EEL A;  1RA2 A;  4DFR A;  3SRR X;  1IA1 A;  1DRF A;  1DHF A;  2BLA A;  3DRC A;  4QI9 A;  1PD9 A;  4HOE A;  4HA9 A;  4KJK A;  3E0B A;  3FL9 A;  3DFR A;  2ITH A;  2BL9 A;  3IRM A;  5U27 A;  1RC4 A;  2XW7 A;  4QLE A;  2JYB A;  5HT5 A;  5HQZ A;  1DR7 A;  1BOZ A;  2KGK A;  2W3V A;  4X5I A;  2OBC A;  3IA4 A;  4P68 A;  3R33 A;  2DHF A;  3F0U X;  3EX8 A;  2FZI A;  4KM2 A;  3F8Y A;  3F0Q X;  5EAJ A;  1RB2 A;  4KBN A;  4KL9 A;  5U26 A;  3TQ8 A;  4Q0D A;  3CSE A;  2CIG A;  1RX9 A;  3JTW A;  1QZF A;  3NZD A;  6DFR A;  1SEJ A;  3FQO A;  4KFJ A;  3EEK A;  3FYW X;  4KYA A;  1U72 A;  3K2H A;  4ELF A;  4XEC X;  1RX1 A;  4I1N A;  2ZZA A;  1MVS A;  4X5G A;  4IXG X;  4X5H A;  2W3W A;  3NZA X;  3S7A A;  1CZ3 A;  4ELB A;  3JVX A;  5JA3 A;  3D84 X;  1LUD A;  3DL6 A;  2BLB A;  4IXE D;  1DR3 A;  4XT5 A;  1IA2 A;  5JG0 X;  4EIZ A;  3QLS A;  3QLZ A;  5HF2 X;  4FHB A;  4PSY A;  3RO9 A;  1LY4 A;  3UM5 A;  3SAI A;  3DG8 A;  3EEJ A;  5HF0 X;  3KFY A;  4DPH A;  3JWM A;  4DDR A;  1YHO A;  2W3A A;  1DLR A;  3DGA A;  2W9T A;  2INQ A;  1J3J A;  3GHW A;  4M6J A;  5DXV A;  3SGY A;  4Q67 A;  1DRA A;  3DAT A;  4HA7 A;  1PD8 A;  3F8Z A;  4FGG A;  5HUI A;  1J3K A;  4M2X A;  3OAF A;  4XE6 X;  1OHJ A;  4NX7 A;  4PDJ A;  3ZPC A;  1DLS A;  5HSR A;  3SA1 A;  4KD7 A;  2D0K A;  1ZDR A;  2C2T A;  1DR1 A;  3NXX A;  3TQ9 A;  2BLC A;  3FQZ A;  1OHK A;  3HJ3 A;  4KNE A;  1RA1 A;  3GYF A;  1DHI A;  1S3Y A;  5E8Q A;  2HM9 A;  4M6L A;  3FRE X;  4X5J A;  3IA5 A;  4H97 A;  2OIP A;  3SRQ X;  1RX8 A;  3GI2 A;  3JWC A;  3FYV X;  1TDR A;  3NZ9 X;  4XRB A;  1KMS A;  2G6V A;  1BZF A;  4LAH X;  5ECX A;  4H98 A;  3IX9 A;  2QK8 A;  4XT6 A;  4G95 A;  1RX5 A;  5HQY A;  4EJ1 A;  2W9H A;  2FZJ A;  2W3B A;  1DDR A;  3Q1H A;  3IRO A;  3K45 A;  4H95 A;  3KJS A;  2LF1 A;  3F0X X;  4M6K A;  4GH8 A;  1RA8 A;  4ELH A;  1DIU A;  4PTJ A;  1D1G A;  3DL5 A;  1RB3 A;  4M7U A;  2AZN A;  3HBB A;  3NXY A;  1DHJ A;  7DFR A;  5CC9 A;  1M78 A;  3KY8 A;  4PSS A;  3NXO A;  3SH2 A;  3QLW A;  1HFR A;  4HOG A;  4CD2 A;  3NXV A;  1DDS A;  4HOF A;  3K74 A;  4P3Q A;  4KAK A;  3JWF A;  4G8Z X;  4KM0 A;  1U71 A;  1RD7 A;  3UM6 A;  1AOE A;  3NZC X;  1RA3 A;  1JOL A;  3NRR A;  4Q6A A;  3I3R A;  5CCC A;  3TQB A;  1DYJ A;  1J3I A;  3FQ0 A;  4ELE A;  1RX4 A;  1M7A A;  1RE7 A;  1M79 A;  3NXR A;  1DRH A;  5ECC A;  4QJZ D;  2HXV A;  3QLY A;  3F0S X;  3ZPG A;  3S9U A;  1RH3 A;  4DP3 A;  2DRC A;  2GD9 A;  2P4G A;  4QLG A;  1DR5 A;  3INV A;  3NZB X;  3CL9 A;  3RG9 A;  3LG4 A;  3FRD X;  2O7P A;  4LAG X;  2D5N A;  3TD8 A;  2B3Z A;  3TQA A;  3FQF A;  2W3M A;  4LAE X;  3FL8 A;  4PST A;  3I8A X;  3KGY A;  1RA9 A;  4LEK X;  3D80 A;  1VDR A;  4RGC A;  2ANQ A;  3QGT A;  3UM8 A;  3QFX A;  4NX6 A;  3SRS X;  3N0H A;  4XT4 A;  3EIG A;  1CD2 A;  4KY8 A;  4X5F A;  1HFQ A;  1VJ3 A;  5HT4 A;  3FY9 X;  3FRF X;  3F0B X;  3QL3 A;  5FDA A;  3CLB A;  4P66 A;  1PDB A;  3FRB X;  3CD2 A;  4KJL A;  3S3V A;  1DRB A;  1RX2 A;  1RG7 A;  2CD2 A;  1DR2 A;  3KJR A;  1DYI A;  3QYO A;  1DYH A;  4OR7 A;  3JW3 A;  5DFR A;  1KLK A;  3JWK A;  2W9S A;  5HSU A;  4P3R A;  4FGH A;  3QYL A;  4DPD A;  3NU0 A;  2L28 A;  3F0V X;  4OSG A;  4KLX A;  1AI9 A;  3K47 A;  3QL0 A;  1DF7 A;  4IXF X;  1RX7 A;  3M09 A;  1LY3 A;  4KEB A;  2C2S A;  1KMV A;  4XT7 A;  5HPB A;  1DG8 A;  3SR5 X;  4EIL A;  4KY4 A;  3L3R A;  4QJC A;  3GHC A;  1S3W A;  1IA3 A;  4QHV A;  2FZH A;  2ANO A;  3DAU A;  1DG7 A;  4EIG A;  3QLX A;  3JSU A;  3NZ6 X;  1RX6 A;  3FQC A;  1JUV A;  4XT8 A;  1S3V A;  1DYR A;  3NXT A;  3SQY X;  1IA4 A;  1DR4 A;  1RF7 A;  3M08 A;  1DRE A;  4ELG A;  1U70 A;  1S3U A;  4ECK A;  1DG5 A;  3FS6 A;  3FRA X;  2HQP A;  3SRW X;  4G3M A;  4QLF A;  1DAJ A;  5HI6 A;  3EEM A;  4PTH A;  3F91 A;  1JOM A;  1E26 A;  3SA2 A;  3JW5 A;  3IRN A;  5HVB A;  4KJJ A;  4M7V A;  3QLR A;  1DIS A;  2H2Q A;  3NTZ A;  3SRU X;  3VCO A;  1MVT A;  3ROA A;  3GHV A;  1DR6 A;  1RX3 A;  4H96 A;  4TU5 X;  8DFR A;  3FY8 X;  1AO8 A;  3QG2 A; 
#chains in the Genus database with same CATH homology
 1HFP A;  4Q0E A;  4I13 A;  2W9G A;  3FQV A;  3OCH A;  5HVE A;  3EEL A;  1RA2 A;  4DFR A;  3SRR X;  1IA1 A;  1DRF A;  1DHF A;  2BLA A;  3DRC A;  4QI9 A;  1PD9 A;  4HOE A;  4HA9 A;  4KJK A;  3E0B A;  3FL9 A;  3DFR A;  2ITH A;  2BL9 A;  3IRM A;  5U27 A;  1RC4 A;  2XW7 A;  4QLE A;  2JYB A;  5HT5 A;  5HQZ A;  1DR7 A;  1BOZ A;  2KGK A;  2W3V A;  4X5I A;  2OBC A;  3IA4 A;  4P68 A;  3R33 A;  2DHF A;  3F0U X;  3EX8 A;  2FZI A;  4KM2 A;  3F8Y A;  3F0Q X;  5EAJ A;  1RB2 A;  4KBN A;  4KL9 A;  5U26 A;  3TQ8 A;  4Q0D A;  3CSE A;  2CIG A;  1RX9 A;  3JTW A;  1QZF A;  3NZD A;  6DFR A;  1SEJ A;  3FQO A;  4KFJ A;  3EEK A;  3FYW X;  4KYA A;  1U72 A;  3K2H A;  4ELF A;  4XEC X;  1RX1 A;  4I1N A;  2ZZA A;  1MVS A;  4X5G A;  4IXG X;  4X5H A;  2W3W A;  3NZA X;  3S7A A;  1CZ3 A;  4ELB A;  3JVX A;  5JA3 A;  3D84 X;  1LUD A;  3DL6 A;  2BLB A;  4IXE D;  1DR3 A;  4XT5 A;  1IA2 A;  5JG0 X;  4EIZ A;  3QLS A;  3QLZ A;  5HF2 X;  4FHB A;  4PSY A;  3RO9 A;  1LY4 A;  3UM5 A;  3SAI A;  3DG8 A;  3EEJ A;  5HF0 X;  3KFY A;  4DPH A;  3JWM A;  4DDR A;  1YHO A;  2W3A A;  1DLR A;  3DGA A;  2W9T A;  2INQ A;  1J3J A;  3GHW A;  4M6J A;  5DXV A;  3SGY A;  4Q67 A;  1DRA A;  3DAT A;  4HA7 A;  1PD8 A;  3F8Z A;  4FGG A;  5HUI A;  1J3K A;  4M2X A;  3OAF A;  4XE6 X;  1OHJ A;  4NX7 A;  4PDJ A;  3ZPC A;  1DLS A;  5HSR A;  3SA1 A;  4KD7 A;  2D0K A;  1ZDR A;  2C2T A;  1DR1 A;  3NXX A;  3TQ9 A;  2BLC A;  3FQZ A;  1OHK A;  3HJ3 A;  4KNE A;  1RA1 A;  3GYF A;  1DHI A;  1S3Y A;  5E8Q A;  2HM9 A;  4M6L A;  3FRE X;  4X5J A;  3IA5 A;  4H97 A;  2OIP A;  3SRQ X;  1RX8 A;  3GI2 A;  3JWC A;  3FYV X;  1TDR A;  3NZ9 X;  4XRB A;  1KMS A;  2G6V A;  1BZF A;  4LAH X;  5ECX A;  4H98 A;  3IX9 A;  2QK8 A;  4XT6 A;  4G95 A;  1RX5 A;  5HQY A;  4EJ1 A;  2W9H A;  2FZJ A;  2W3B A;  1DDR A;  3Q1H A;  3IRO A;  3K45 A;  4H95 A;  3KJS A;  2LF1 A;  3F0X X;  4M6K A;  4GH8 A;  1RA8 A;  4ELH A;  1DIU A;  4PTJ A;  1D1G A;  3DL5 A;  1RB3 A;  4M7U A;  2AZN A;  3HBB A;  3NXY A;  1DHJ A;  7DFR A;  5CC9 A;  1M78 A;  3KY8 A;  4PSS A;  3NXO A;  3SH2 A;  3QLW A;  1HFR A;  4HOG A;  4CD2 A;  3NXV A;  1DDS A;  4HOF A;  3K74 A;  4P3Q A;  4KAK A;  3JWF A;  4G8Z X;  4KM0 A;  1U71 A;  1RD7 A;  3UM6 A;  1AOE A;  3NZC X;  1RA3 A;  1JOL A;  3NRR A;  4Q6A A;  3I3R A;  5CCC A;  3TQB A;  1DYJ A;  1J3I A;  3FQ0 A;  4ELE A;  1RX4 A;  1M7A A;  1RE7 A;  1M79 A;  3NXR A;  1DRH A;  5ECC A;  4QJZ D;  2HXV A;  3QLY A;  3F0S X;  3ZPG A;  3S9U A;  1RH3 A;  4DP3 A;  2DRC A;  2GD9 A;  2P4G A;  4QLG A;  1DR5 A;  3INV A;  3NZB X;  3CL9 A;  3RG9 A;  3LG4 A;  3FRD X;  2O7P A;  4LAG X;  2D5N A;  3TD8 A;  2B3Z A;  3TQA A;  3FQF A;  2W3M A;  4LAE X;  3FL8 A;  4PST A;  3I8A X;  3KGY A;  1RA9 A;  4LEK X;  3D80 A;  1VDR A;  4RGC A;  2ANQ A;  3QGT A;  3UM8 A;  3QFX A;  4NX6 A;  3SRS X;  3N0H A;  4XT4 A;  3EIG A;  1CD2 A;  4KY8 A;  4X5F A;  1HFQ A;  1VJ3 A;  5HT4 A;  3FY9 X;  3FRF X;  3F0B X;  3QL3 A;  5FDA A;  3CLB A;  4P66 A;  1PDB A;  3FRB X;  3CD2 A;  4KJL A;  3S3V A;  1DRB A;  1RX2 A;  1RG7 A;  2CD2 A;  1DR2 A;  3KJR A;  1DYI A;  3QYO A;  1DYH A;  4OR7 A;  3JW3 A;  5DFR A;  1KLK A;  3JWK A;  2W9S A;  5HSU A;  4P3R A;  4FGH A;  3QYL A;  4DPD A;  3NU0 A;  2L28 A;  3F0V X;  4OSG A;  4KLX A;  1AI9 A;  3K47 A;  3QL0 A;  1DF7 A;  4IXF X;  1RX7 A;  3M09 A;  1LY3 A;  4KEB A;  2C2S A;  1KMV A;  4XT7 A;  5HPB A;  1DG8 A;  3SR5 X;  4EIL A;  4KY4 A;  3L3R A;  4QJC A;  3GHC A;  1S3W A;  1IA3 A;  4QHV A;  2FZH A;  2ANO A;  3DAU A;  1DG7 A;  4EIG A;  3QLX A;  3JSU A;  3NZ6 X;  1RX6 A;  3FQC A;  1JUV A;  4XT8 A;  1S3V A;  1DYR A;  3NXT A;  3SQY X;  1IA4 A;  1DR4 A;  1RF7 A;  3M08 A;  1DRE A;  4ELG A;  1U70 A;  1S3U A;  4ECK A;  1DG5 A;  3FS6 A;  3FRA X;  2HQP A;  3SRW X;  4G3M A;  4QLF A;  1DAJ A;  5HI6 A;  3EEM A;  4PTH A;  3F91 A;  1JOM A;  1E26 A;  3SA2 A;  3JW5 A;  3IRN A;  5HVB A;  4KJJ A;  4M7V A;  3QLR A;  1DIS A;  2H2Q A;  3NTZ A;  3SRU X;  3VCO A;  1MVT A;  3ROA A;  3GHV A;  1DR6 A;  1RX3 A;  4H96 A;  4TU5 X;  8DFR A;  3FY8 X;  1AO8 A;  3QG2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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