3JWCA

Crystal structure of bacillus anthracis (y102f) dihydrofolate reductase complexed with nadph and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (ucp120a)
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
165
structure length
165
Chain Sequence
HHHMRVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIFDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Bacillus anthracis
publication title Targeted Mutations in Bacillus anthracis Dihydrofolate Reductase Condense Complex Structure-Activity Relationships
rcsb
molecule keywords Dihydrofolate reductase
total genus 44
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3jwcA00
1S3WA 2BLAA 1DDRA 2AZNA 3DL5A 3IROA 4ELFA 3NZAX 4ELGA 3QL3A 4QI9A 2BLBA 2FZJA 1DHFA 2DRCA 4X5FA 3TQAA 3M08A 2LF1A 3SAIA 4LAHX 3S3VA 1S3YA 1DHJA 1S3VA 3SRUX 3JW3A 4LEKX 3SA1A 4KLXA 1IA3A 1DLRA 8DFRA 4ELEA 3INVA 2W9HA 4EJ1A 5DFRA 1HFPA 4X5JA 3DL6A 1KMSA 1RA3A 3NXYA 2FZHA 4KAKA 3CLBA 5HSUA 1DG7A 1RA9A 1BOZA 3I3RA 4FGHA 1KMVA 3IA4A 1M79A 5EAJA 1RC4A 2W3MA 3QLSA 2ANOA 5HT5A 3OAFA 2HXVA 1DR7A 3EX8A 3RG9A 3QYOA 1JOMA 4FHBA 1QZFA 4QJCA 3F0SX 4DP3A 2G6VA 2FZIA 4LAEX 1DR3A 1VJ3A 5HSRA 1AI9A 3FRAX 3FL8A 3S7AA 3JSUA 3N0HA 3F91A 3ROAA 3FRBX 4LAGX 3SRWX 4H95A 3SA2A 1DHIA 4M7UA 2HQPA 1DR2A 1DR6A 1ZDRA 3DFRA 2B3ZA 4ECKA 1RA1A 3SRQX 2KGKA 4Q6AA 3FQFA 4KEBA 1RF7A 1DRBA 3NXOA 4FGGA 4P66A 2GD9A 4QHVA 3NZBX 3FREX 1HFRA 5HF2X 4XT5A 3EELA 5HI6A 3GHVA 3TQBA 1S3UA 3CSEA 5HPBA 4X5HA 2OIPA 3SH2A 3JW5A 4QJZD 3QGTA 3S9UA 3FYVX 4HOFA 2W9TA 1U72A 1DF7A 2DHFA 3NZDA 2W3VA 3QL0A 3LG4A 3F0QX 1PDBA 3KJRA 3IRNA 3IRMA 1MVTA 5ECXA 1DR1A 4H98A 4H96A 3KFYA 3DGAA 4KNEA 3EEMA 1DR4A 2D0KA 1AO8A 1D1GA 3D84X 3KY8A 4IXFX 3UM5A 2ANQA 1M78A 4PDJA 3FYWX 3TQ8A 1JUVA 3SGYA 1J3IA 3CL9A 2W3BA 2BLCA 3E0BA 1IA1A 3FQZA 3HBBA 1RA8A 3GHWA 1VDRA 4I1NA 3K47A 1DRHA 1AOEA 3F0BX 3DG8A 2W9GA 4KFJA 3QLXA 3F8ZA 1DLSA 2W3AA 3NTZA 4M6JA 1CZ3A 3QLYA 3F0XX 4HA7A 1YHOA 4PTHA 1U70A 2CD2A 3JWKA 3FY9X 4G95A 2BL9A 4PTJA 1MVSA 2CIGA 4EILA 4HOEA 4I13A 3R33A 3UM6A 4DFRA 2O7PA 1DG5A 4M6LA 4KJLA 1RD7A 3CD2A 4PSYA 3FQ0A 3M09A 4NX6A 4DDRA 1J3KA 4KM2A 2C2TA 3GI2A 1RG7A 3JVXA 3FRDX 3TD8A 4XT7A 4XE6X 4KBNA 7DFRA 4H97A 4XT4A 5ECCA 1M7AA 3NRRA 2D5NA 1RE7A 1HFQA 5HVBA 1DAJA 4OSGA 2L28A 3NXVA 5CCCA 1RA2A 3VCOA 3FS6A 4Q0EA 4DPDA 3NZ9X 3FQCA 4M6KA 3QLWA 5HQYA 3EIGA 5U27A 1CD2A 3K74A 1LY4A 1DIUA 3K2HA 3OCHA 5U26A 1RX6A 4HA9A 1DRAA 4OR7A 3JWCA 4IXED 1SEJA 3HJ3A 2H2QA 3SQYX 3GYFA 5E8QA 5DXVA 4KYAA 5HF0X 5HUIA 3JWMA 4DPHA 1RB2A 4QLFA 1JOLA 1DRFA 4CD2A 1TDRA 4PSSA 1DREA 1RX7A 3NU0A 3NXTA 3F8YA 3IA5A 1LY3A 1DG8A 1RX9A 4EIGA 3K45A 3DAUA 2INQA 3NXRA 4KL9A 4RGCA 4XECX 5HT4A 4HOGA 1J3JA 3FQOA 3NXXA 4KJKA 2QK8A 4IXGX 1RX2A 4P68A 5CC9A 2P4GA 3QLZA 3KJSA 3JTWA 1RX8A 2C2SA 4NX7A 4ELBA 3EEKA 4KJJA 3EEJA 3NZ6X 1RX5A 4KM0A 3I8AX 3QG2A 4P3QA 3F0UX 1LUDA 5JA3A 3JWFA 4GH8A 3L3RA 4Q67A 4PSTA 3SR5X 4ELHA 1E26A 1RH3A 4X5GA 4XT6A 4M7VA 1OHJA 3QYLA 5HVEA 2XW7A 3DRCA 1RX1A 3QFXA 1DYHA 1RB3A 4X5IA 4QLEA 4KY4A 3SRSX 1RX4A 4EIZA 3ZPGA 3DATA 6DFRA 3TQ9A 5JG0X 3Q1HA 3FL9A 3F0VX 3RO9A 4G3MA 3KGYA 1DYJA 4M2XA 5HQZA 1PD9A 1DYRA 3IX9A 2ZZAA 4KD7A 3D80A 1U71A 1RX3A 1DYIA 4TU5X 3FY8X 3UM8A 2ITHA 2OBCA 1IA2A 2HM9A 3NZCX 2W3WA 1DDSA 1KLKA 3FRFX 4Q0DA 3ZPCA 4G8ZX 4KY8A 1PD8A 1BZFA 1DISA 3QLRA 4XRBA 3FQVA 4XT8A 5FDAA 3SRRX 1OHKA 2JYBA 1IA4A 2W9SA 3GHCA 4QLGA 4P3RA 1DR5A
chains in the Genus database with same CATH superfamily
1S3WA 2BLAA 1DDRA 2AZNA 3DL5A 3IROA 4ELFA 3NZAX 4ELGA 3QL3A 4QI9A 2BLBA 2FZJA 1DHFA 2DRCA 4X5FA 3TQAA 3M08A 2LF1A 3SAIA 4LAHX 3S3VA 1S3YA 1DHJA 1S3VA 3SRUX 3JW3A 4LEKX 3SA1A 4KLXA 1IA3A 1DLRA 8DFRA 4ELEA 3INVA 2W9HA 4EJ1A 5DFRA 1HFPA 4X5JA 3DL6A 1KMSA 1RA3A 3NXYA 2FZHA 4KAKA 3CLBA 5HSUA 1DG7A 1RA9A 1BOZA 3I3RA 4FGHA 1KMVA 3IA4A 1M79A 5EAJA 1RC4A 2W3MA 3QLSA 2ANOA 5HT5A 3OAFA 2HXVA 1DR7A 3EX8A 3RG9A 3QYOA 1JOMA 4FHBA 1QZFA 4QJCA 3F0SX 4DP3A 2G6VA 2FZIA 4LAEX 1DR3A 1VJ3A 5HSRA 1AI9A 3FRAX 3FL8A 3S7AA 3JSUA 3N0HA 3F91A 3ROAA 3FRBX 4LAGX 3SRWX 4H95A 3SA2A 1DHIA 4M7UA 2HQPA 1DR2A 1DR6A 1ZDRA 3DFRA 2B3ZA 4ECKA 1RA1A 3SRQX 2KGKA 4Q6AA 3FQFA 4KEBA 1RF7A 1DRBA 3NXOA 4FGGA 4P66A 2GD9A 4QHVA 3NZBX 3FREX 1HFRA 5HF2X 4XT5A 3EELA 5HI6A 3GHVA 3TQBA 1S3UA 3CSEA 5HPBA 4X5HA 2OIPA 3SH2A 3JW5A 4QJZD 3QGTA 3S9UA 3FYVX 4HOFA 2W9TA 1U72A 1DF7A 2DHFA 3NZDA 2W3VA 3QL0A 3LG4A 3F0QX 1PDBA 3KJRA 3IRNA 3IRMA 1MVTA 5ECXA 1DR1A 4H98A 4H96A 3KFYA 3DGAA 4KNEA 3EEMA 1DR4A 2D0KA 1AO8A 1D1GA 3D84X 3KY8A 4IXFX 3UM5A 2ANQA 1M78A 4PDJA 3FYWX 3TQ8A 1JUVA 3SGYA 1J3IA 3CL9A 2W3BA 2BLCA 3E0BA 1IA1A 3FQZA 3HBBA 1RA8A 3GHWA 1VDRA 4I1NA 3K47A 1DRHA 1AOEA 3F0BX 3DG8A 2W9GA 4KFJA 3QLXA 3F8ZA 1DLSA 2W3AA 3NTZA 4M6JA 1CZ3A 3QLYA 3F0XX 4HA7A 1YHOA 4PTHA 1U70A 2CD2A 3JWKA 3FY9X 4G95A 2BL9A 4PTJA 1MVSA 2CIGA 4EILA 4HOEA 4I13A 3R33A 3UM6A 4DFRA 2O7PA 1DG5A 4M6LA 4KJLA 1RD7A 3CD2A 4PSYA 3FQ0A 3M09A 4NX6A 4DDRA 1J3KA 4KM2A 2C2TA 3GI2A 1RG7A 3JVXA 3FRDX 3TD8A 4XT7A 4XE6X 4KBNA 7DFRA 4H97A 4XT4A 5ECCA 1M7AA 3NRRA 2D5NA 1RE7A 1HFQA 5HVBA 1DAJA 4OSGA 2L28A 3NXVA 5CCCA 1RA2A 3VCOA 3FS6A 4Q0EA 4DPDA 3NZ9X 3FQCA 4M6KA 3QLWA 5HQYA 3EIGA 5U27A 1CD2A 3K74A 1LY4A 1DIUA 3K2HA 3OCHA 5U26A 1RX6A 4HA9A 1DRAA 4OR7A 3JWCA 4IXED 1SEJA 3HJ3A 2H2QA 3SQYX 3GYFA 5E8QA 5DXVA 4KYAA 5HF0X 5HUIA 3JWMA 4DPHA 1RB2A 4QLFA 1JOLA 1DRFA 4CD2A 1TDRA 4PSSA 1DREA 1RX7A 3NU0A 3NXTA 3F8YA 3IA5A 1LY3A 1DG8A 1RX9A 4EIGA 3K45A 3DAUA 2INQA 3NXRA 4KL9A 4RGCA 4XECX 5HT4A 4HOGA 1J3JA 3FQOA 3NXXA 4KJKA 2QK8A 4IXGX 1RX2A 4P68A 5CC9A 2P4GA 3QLZA 3KJSA 3JTWA 1RX8A 2C2SA 4NX7A 4ELBA 3EEKA 4KJJA 3EEJA 3NZ6X 1RX5A 4KM0A 3I8AX 3QG2A 4P3QA 3F0UX 1LUDA 5JA3A 3JWFA 4GH8A 3L3RA 4Q67A 4PSTA 3SR5X 4ELHA 1E26A 1RH3A 4X5GA 4XT6A 4M7VA 1OHJA 3QYLA 5HVEA 2XW7A 3DRCA 1RX1A 3QFXA 1DYHA 1RB3A 4X5IA 4QLEA 4KY4A 3SRSX 1RX4A 4EIZA 3ZPGA 3DATA 6DFRA 3TQ9A 5JG0X 3Q1HA 3FL9A 3F0VX 3RO9A 4G3MA 3KGYA 1DYJA 4M2XA 5HQZA 1PD9A 1DYRA 3IX9A 2ZZAA 4KD7A 3D80A 1U71A 1RX3A 1DYIA 4TU5X 3FY8X 3UM8A 2ITHA 2OBCA 1IA2A 2HM9A 3NZCX 2W3WA 1DDSA 1KLKA 3FRFX 4Q0DA 3ZPCA 4G8ZX 4KY8A 1PD8A 1BZFA 1DISA 3QLRA 4XRBA 3FQVA 4XT8A 5FDAA 3SRRX 1OHKA 2JYBA 1IA4A 2W9SA 3GHCA 4QLGA 4P3RA 1DR5A
chains in the Genus database with same CATH topology
1S3WA 2BLAA 1DDRA 2AZNA 3DL5A 3IROA 4ELFA 3NZAX 4ELGA 3QL3A 4QI9A 2BLBA 2FZJA 1DHFA 2DRCA 4X5FA 3TQAA 3M08A 2LF1A 3SAIA 4LAHX 3S3VA 1S3YA 1DHJA 1S3VA 3SRUX 3JW3A 4LEKX 3SA1A 4KLXA 1IA3A 1DLRA 8DFRA 4ELEA 3INVA 2W9HA 4EJ1A 5DFRA 1HFPA 4X5JA 3DL6A 1KMSA 1RA3A 3NXYA 2FZHA 4KAKA 3CLBA 5HSUA 1DG7A 1RA9A 1BOZA 3I3RA 4FGHA 1KMVA 3IA4A 1M79A 5EAJA 1RC4A 2W3MA 3QLSA 2ANOA 5HT5A 3OAFA 2HXVA 1DR7A 3EX8A 3RG9A 3QYOA 1JOMA 4FHBA 1QZFA 4QJCA 3F0SX 4DP3A 2G6VA 2FZIA 4LAEX 1DR3A 1VJ3A 5HSRA 1AI9A 3FRAX 3FL8A 3S7AA 3JSUA 3N0HA 3F91A 3ROAA 3FRBX 4LAGX 3SRWX 4H95A 3SA2A 1DHIA 4M7UA 2HQPA 1DR2A 1DR6A 1ZDRA 3DFRA 2B3ZA 4ECKA 1RA1A 3SRQX 2KGKA 4Q6AA 3FQFA 4KEBA 1RF7A 1DRBA 3NXOA 4FGGA 4P66A 2GD9A 4QHVA 3NZBX 3FREX 1HFRA 5HF2X 4XT5A 3EELA 5HI6A 3GHVA 3TQBA 1S3UA 3CSEA 5HPBA 4X5HA 2OIPA 3SH2A 3JW5A 4QJZD 3QGTA 3S9UA 3FYVX 4HOFA 2W9TA 1U72A 1DF7A 2DHFA 3NZDA 2W3VA 3QL0A 3LG4A 3F0QX 1PDBA 3KJRA 3IRNA 3IRMA 1MVTA 5ECXA 1DR1A 4H98A 4H96A 3KFYA 3DGAA 4KNEA 3EEMA 1DR4A 2D0KA 1AO8A 1D1GA 3D84X 3KY8A 4IXFX 3UM5A 2ANQA 1M78A 4PDJA 3FYWX 3TQ8A 1JUVA 3SGYA 1J3IA 3CL9A 2W3BA 2BLCA 3E0BA 1IA1A 3FQZA 3HBBA 1RA8A 3GHWA 1VDRA 4I1NA 3K47A 1DRHA 1AOEA 3F0BX 3DG8A 2W9GA 4KFJA 3QLXA 3F8ZA 1DLSA 2W3AA 3NTZA 4M6JA 1CZ3A 3QLYA 3F0XX 4HA7A 1YHOA 4PTHA 1U70A 2CD2A 3JWKA 3FY9X 4G95A 2BL9A 4PTJA 1MVSA 2CIGA 4EILA 4HOEA 4I13A 3R33A 3UM6A 4DFRA 2O7PA 1DG5A 4M6LA 4KJLA 1RD7A 3CD2A 4PSYA 3FQ0A 3M09A 4NX6A 4DDRA 1J3KA 4KM2A 2C2TA 3GI2A 1RG7A 3JVXA 3FRDX 3TD8A 4XT7A 4XE6X 4KBNA 7DFRA 4H97A 4XT4A 5ECCA 1M7AA 3NRRA 2D5NA 1RE7A 1HFQA 5HVBA 1DAJA 4OSGA 2L28A 3NXVA 5CCCA 1RA2A 3VCOA 3FS6A 4Q0EA 4DPDA 3NZ9X 3FQCA 4M6KA 3QLWA 5HQYA 3EIGA 5U27A 1CD2A 3K74A 1LY4A 1DIUA 3K2HA 3OCHA 5U26A 1RX6A 4HA9A 1DRAA 4OR7A 3JWCA 4IXED 1SEJA 3HJ3A 2H2QA 3SQYX 3GYFA 5E8QA 5DXVA 4KYAA 5HF0X 5HUIA 3JWMA 4DPHA 1RB2A 4QLFA 1JOLA 1DRFA 4CD2A 1TDRA 4PSSA 1DREA 1RX7A 3NU0A 3NXTA 3F8YA 3IA5A 1LY3A 1DG8A 1RX9A 4EIGA 3K45A 3DAUA 2INQA 3NXRA 4KL9A 4RGCA 4XECX 5HT4A 4HOGA 1J3JA 3FQOA 3NXXA 4KJKA 2QK8A 4IXGX 1RX2A 4P68A 5CC9A 2P4GA 3QLZA 3KJSA 3JTWA 1RX8A 2C2SA 4NX7A 4ELBA 3EEKA 4KJJA 3EEJA 3NZ6X 1RX5A 4KM0A 3I8AX 3QG2A 4P3QA 3F0UX 1LUDA 5JA3A 3JWFA 4GH8A 3L3RA 4Q67A 4PSTA 3SR5X 4ELHA 1E26A 1RH3A 4X5GA 4XT6A 4M7VA 1OHJA 3QYLA 5HVEA 2XW7A 3DRCA 1RX1A 3QFXA 1DYHA 1RB3A 4X5IA 4QLEA 4KY4A 3SRSX 1RX4A 4EIZA 3ZPGA 3DATA 6DFRA 3TQ9A 5JG0X 3Q1HA 3FL9A 3F0VX 3RO9A 4G3MA 3KGYA 1DYJA 4M2XA 5HQZA 1PD9A 1DYRA 3IX9A 2ZZAA 4KD7A 3D80A 1U71A 1RX3A 1DYIA 4TU5X 3FY8X 3UM8A 2ITHA 2OBCA 1IA2A 2HM9A 3NZCX 2W3WA 1DDSA 1KLKA 3FRFX 4Q0DA 3ZPCA 4G8ZX 4KY8A 1PD8A 1BZFA 1DISA 3QLRA 4XRBA 3FQVA 4XT8A 5FDAA 3SRRX 1OHKA 2JYBA 1IA4A 2W9SA 3GHCA 4QLGA 4P3RA 1DR5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S3W A;  2BLA A;  1DDR A;  2AZN A;  3DL5 A;  3IRO A;  4ELF A;  3NZA X;  4ELG A;  3QL3 A;  4QI9 A;  2BLB A;  2FZJ A;  1DHF A;  2DRC A;  4X5F A;  3TQA A;  3M08 A;  2LF1 A;  3SAI A;  4LAH X;  3S3V A;  1S3Y A;  1DHJ A;  1S3V A;  3SRU X;  3JW3 A;  4LEK X;  3SA1 A;  4KLX A;  1IA3 A;  1DLR A;  8DFR A;  4ELE A;  3INV A;  2W9H A;  4EJ1 A;  5DFR A;  1HFP A;  4X5J A;  3DL6 A;  1KMS A;  1RA3 A;  3NXY A;  2FZH A;  4KAK A;  3CLB A;  5HSU A;  1DG7 A;  1RA9 A;  1BOZ A;  3I3R A;  4FGH A;  1KMV A;  3IA4 A;  1M79 A;  5EAJ A;  1RC4 A;  2W3M A;  3QLS A;  2ANO A;  5HT5 A;  3OAF A;  2HXV A;  1DR7 A;  3EX8 A;  3RG9 A;  3QYO A;  1JOM A;  4FHB A;  1QZF A;  4QJC A;  3F0S X;  4DP3 A;  2G6V A;  2FZI A;  4LAE X;  1DR3 A;  1VJ3 A;  5HSR A;  1AI9 A;  3FRA X;  3FL8 A;  3S7A A;  3JSU A;  3N0H A;  3F91 A;  3ROA A;  3FRB X;  4LAG X;  3SRW X;  4H95 A;  3SA2 A;  1DHI A;  4M7U A;  2HQP A;  1DR2 A;  1DR6 A;  1ZDR A;  3DFR A;  2B3Z A;  4ECK A;  1RA1 A;  3SRQ X;  2KGK A;  4Q6A A;  3FQF A;  4KEB A;  1RF7 A;  1DRB A;  3NXO A;  4FGG A;  4P66 A;  2GD9 A;  4QHV A;  3NZB X;  3FRE X;  1HFR A;  5HF2 X;  4XT5 A;  3EEL A;  5HI6 A;  3GHV A;  3TQB A;  1S3U A;  3CSE A;  5HPB A;  4X5H A;  2OIP A;  3SH2 A;  3JW5 A;  4QJZ D;  3QGT A;  3S9U A;  3FYV X;  4HOF A;  2W9T A;  1U72 A;  1DF7 A;  2DHF A;  3NZD A;  2W3V A;  3QL0 A;  3LG4 A;  3F0Q X;  1PDB A;  3KJR A;  3IRN A;  3IRM A;  1MVT A;  5ECX A;  1DR1 A;  4H98 A;  4H96 A;  3KFY A;  3DGA A;  4KNE A;  3EEM A;  1DR4 A;  2D0K A;  1AO8 A;  1D1G A;  3D84 X;  3KY8 A;  4IXF X;  3UM5 A;  2ANQ A;  1M78 A;  4PDJ A;  3FYW X;  3TQ8 A;  1JUV A;  3SGY A;  1J3I A;  3CL9 A;  2W3B A;  2BLC A;  3E0B A;  1IA1 A;  3FQZ A;  3HBB A;  1RA8 A;  3GHW A;  1VDR A;  4I1N A;  3K47 A;  1DRH A;  1AOE A;  3F0B X;  3DG8 A;  2W9G A;  4KFJ A;  3QLX A;  3F8Z A;  1DLS A;  2W3A A;  3NTZ A;  4M6J A;  1CZ3 A;  3QLY A;  3F0X X;  4HA7 A;  1YHO A;  4PTH A;  1U70 A;  2CD2 A;  3JWK A;  3FY9 X;  4G95 A;  2BL9 A;  4PTJ A;  1MVS A;  2CIG A;  4EIL A;  4HOE A;  4I13 A;  3R33 A;  3UM6 A;  4DFR A;  2O7P A;  1DG5 A;  4M6L A;  4KJL A;  1RD7 A;  3CD2 A;  4PSY A;  3FQ0 A;  3M09 A;  4NX6 A;  4DDR A;  1J3K A;  4KM2 A;  2C2T A;  3GI2 A;  1RG7 A;  3JVX A;  3FRD X;  3TD8 A;  4XT7 A;  4XE6 X;  4KBN A;  7DFR A;  4H97 A;  4XT4 A;  5ECC A;  1M7A A;  3NRR A;  2D5N A;  1RE7 A;  1HFQ A;  5HVB A;  1DAJ A;  4OSG A;  2L28 A;  3NXV A;  5CCC A;  1RA2 A;  3VCO A;  3FS6 A;  4Q0E A;  4DPD A;  3NZ9 X;  3FQC A;  4M6K A;  3QLW A;  5HQY A;  3EIG A;  5U27 A;  1CD2 A;  3K74 A;  1LY4 A;  1DIU A;  3K2H A;  3OCH A;  5U26 A;  1RX6 A;  4HA9 A;  1DRA A;  4OR7 A;  3JWC A;  4IXE D;  1SEJ A;  3HJ3 A;  2H2Q A;  3SQY X;  3GYF A;  5E8Q A;  5DXV A;  4KYA A;  5HF0 X;  5HUI A;  3JWM A;  4DPH A;  1RB2 A;  4QLF A;  1JOL A;  1DRF A;  4CD2 A;  1TDR A;  4PSS A;  1DRE A;  1RX7 A;  3NU0 A;  3NXT A;  3F8Y A;  3IA5 A;  1LY3 A;  1DG8 A;  1RX9 A;  4EIG A;  3K45 A;  3DAU A;  2INQ A;  3NXR A;  4KL9 A;  4RGC A;  4XEC X;  5HT4 A;  4HOG A;  1J3J A;  3FQO A;  3NXX A;  4KJK A;  2QK8 A;  4IXG X;  1RX2 A;  4P68 A;  5CC9 A;  2P4G A;  3QLZ A;  3KJS A;  3JTW A;  1RX8 A;  2C2S A;  4NX7 A;  4ELB A;  3EEK A;  4KJJ A;  3EEJ A;  3NZ6 X;  1RX5 A;  4KM0 A;  3I8A X;  3QG2 A;  4P3Q A;  3F0U X;  1LUD A;  5JA3 A;  3JWF A;  4GH8 A;  3L3R A;  4Q67 A;  4PST A;  3SR5 X;  4ELH A;  1E26 A;  1RH3 A;  4X5G A;  4XT6 A;  4M7V A;  1OHJ A;  3QYL A;  5HVE A;  2XW7 A;  3DRC A;  1RX1 A;  3QFX A;  1DYH A;  1RB3 A;  4X5I A;  4QLE A;  4KY4 A;  3SRS X;  1RX4 A;  4EIZ A;  3ZPG A;  3DAT A;  6DFR A;  3TQ9 A;  5JG0 X;  3Q1H A;  3FL9 A;  3F0V X;  3RO9 A;  4G3M A;  3KGY A;  1DYJ A;  4M2X A;  5HQZ A;  1PD9 A;  1DYR A;  3IX9 A;  2ZZA A;  4KD7 A;  3D80 A;  1U71 A;  1RX3 A;  1DYI A;  4TU5 X;  3FY8 X;  3UM8 A;  2ITH A;  2OBC A;  1IA2 A;  2HM9 A;  3NZC X;  2W3W A;  1DDS A;  1KLK A;  3FRF X;  4Q0D A;  3ZPC A;  4G8Z X;  4KY8 A;  1PD8 A;  1BZF A;  1DIS A;  3QLR A;  4XRB A;  3FQV A;  4XT8 A;  5FDA A;  3SRR X;  1OHK A;  2JYB A;  1IA4 A;  2W9S A;  3GHC A;  4QLG A;  4P3R A;  1DR5 A; 
#chains in the Genus database with same CATH topology
 1S3W A;  2BLA A;  1DDR A;  2AZN A;  3DL5 A;  3IRO A;  4ELF A;  3NZA X;  4ELG A;  3QL3 A;  4QI9 A;  2BLB A;  2FZJ A;  1DHF A;  2DRC A;  4X5F A;  3TQA A;  3M08 A;  2LF1 A;  3SAI A;  4LAH X;  3S3V A;  1S3Y A;  1DHJ A;  1S3V A;  3SRU X;  3JW3 A;  4LEK X;  3SA1 A;  4KLX A;  1IA3 A;  1DLR A;  8DFR A;  4ELE A;  3INV A;  2W9H A;  4EJ1 A;  5DFR A;  1HFP A;  4X5J A;  3DL6 A;  1KMS A;  1RA3 A;  3NXY A;  2FZH A;  4KAK A;  3CLB A;  5HSU A;  1DG7 A;  1RA9 A;  1BOZ A;  3I3R A;  4FGH A;  1KMV A;  3IA4 A;  1M79 A;  5EAJ A;  1RC4 A;  2W3M A;  3QLS A;  2ANO A;  5HT5 A;  3OAF A;  2HXV A;  1DR7 A;  3EX8 A;  3RG9 A;  3QYO A;  1JOM A;  4FHB A;  1QZF A;  4QJC A;  3F0S X;  4DP3 A;  2G6V A;  2FZI A;  4LAE X;  1DR3 A;  1VJ3 A;  5HSR A;  1AI9 A;  3FRA X;  3FL8 A;  3S7A A;  3JSU A;  3N0H A;  3F91 A;  3ROA A;  3FRB X;  4LAG X;  3SRW X;  4H95 A;  3SA2 A;  1DHI A;  4M7U A;  2HQP A;  1DR2 A;  1DR6 A;  1ZDR A;  3DFR A;  2B3Z A;  4ECK A;  1RA1 A;  3SRQ X;  2KGK A;  4Q6A A;  3FQF A;  4KEB A;  1RF7 A;  1DRB A;  3NXO A;  4FGG A;  4P66 A;  2GD9 A;  4QHV A;  3NZB X;  3FRE X;  1HFR A;  5HF2 X;  4XT5 A;  3EEL A;  5HI6 A;  3GHV A;  3TQB A;  1S3U A;  3CSE A;  5HPB A;  4X5H A;  2OIP A;  3SH2 A;  3JW5 A;  4QJZ D;  3QGT A;  3S9U A;  3FYV X;  4HOF A;  2W9T A;  1U72 A;  1DF7 A;  2DHF A;  3NZD A;  2W3V A;  3QL0 A;  3LG4 A;  3F0Q X;  1PDB A;  3KJR A;  3IRN A;  3IRM A;  1MVT A;  5ECX A;  1DR1 A;  4H98 A;  4H96 A;  3KFY A;  3DGA A;  4KNE A;  3EEM A;  1DR4 A;  2D0K A;  1AO8 A;  1D1G A;  3D84 X;  3KY8 A;  4IXF X;  3UM5 A;  2ANQ A;  1M78 A;  4PDJ A;  3FYW X;  3TQ8 A;  1JUV A;  3SGY A;  1J3I A;  3CL9 A;  2W3B A;  2BLC A;  3E0B A;  1IA1 A;  3FQZ A;  3HBB A;  1RA8 A;  3GHW A;  1VDR A;  4I1N A;  3K47 A;  1DRH A;  1AOE A;  3F0B X;  3DG8 A;  2W9G A;  4KFJ A;  3QLX A;  3F8Z A;  1DLS A;  2W3A A;  3NTZ A;  4M6J A;  1CZ3 A;  3QLY A;  3F0X X;  4HA7 A;  1YHO A;  4PTH A;  1U70 A;  2CD2 A;  3JWK A;  3FY9 X;  4G95 A;  2BL9 A;  4PTJ A;  1MVS A;  2CIG A;  4EIL A;  4HOE A;  4I13 A;  3R33 A;  3UM6 A;  4DFR A;  2O7P A;  1DG5 A;  4M6L A;  4KJL A;  1RD7 A;  3CD2 A;  4PSY A;  3FQ0 A;  3M09 A;  4NX6 A;  4DDR A;  1J3K A;  4KM2 A;  2C2T A;  3GI2 A;  1RG7 A;  3JVX A;  3FRD X;  3TD8 A;  4XT7 A;  4XE6 X;  4KBN A;  7DFR A;  4H97 A;  4XT4 A;  5ECC A;  1M7A A;  3NRR A;  2D5N A;  1RE7 A;  1HFQ A;  5HVB A;  1DAJ A;  4OSG A;  2L28 A;  3NXV A;  5CCC A;  1RA2 A;  3VCO A;  3FS6 A;  4Q0E A;  4DPD A;  3NZ9 X;  3FQC A;  4M6K A;  3QLW A;  5HQY A;  3EIG A;  5U27 A;  1CD2 A;  3K74 A;  1LY4 A;  1DIU A;  3K2H A;  3OCH A;  5U26 A;  1RX6 A;  4HA9 A;  1DRA A;  4OR7 A;  3JWC A;  4IXE D;  1SEJ A;  3HJ3 A;  2H2Q A;  3SQY X;  3GYF A;  5E8Q A;  5DXV A;  4KYA A;  5HF0 X;  5HUI A;  3JWM A;  4DPH A;  1RB2 A;  4QLF A;  1JOL A;  1DRF A;  4CD2 A;  1TDR A;  4PSS A;  1DRE A;  1RX7 A;  3NU0 A;  3NXT A;  3F8Y A;  3IA5 A;  1LY3 A;  1DG8 A;  1RX9 A;  4EIG A;  3K45 A;  3DAU A;  2INQ A;  3NXR A;  4KL9 A;  4RGC A;  4XEC X;  5HT4 A;  4HOG A;  1J3J A;  3FQO A;  3NXX A;  4KJK A;  2QK8 A;  4IXG X;  1RX2 A;  4P68 A;  5CC9 A;  2P4G A;  3QLZ A;  3KJS A;  3JTW A;  1RX8 A;  2C2S A;  4NX7 A;  4ELB A;  3EEK A;  4KJJ A;  3EEJ A;  3NZ6 X;  1RX5 A;  4KM0 A;  3I8A X;  3QG2 A;  4P3Q A;  3F0U X;  1LUD A;  5JA3 A;  3JWF A;  4GH8 A;  3L3R A;  4Q67 A;  4PST A;  3SR5 X;  4ELH A;  1E26 A;  1RH3 A;  4X5G A;  4XT6 A;  4M7V A;  1OHJ A;  3QYL A;  5HVE A;  2XW7 A;  3DRC A;  1RX1 A;  3QFX A;  1DYH A;  1RB3 A;  4X5I A;  4QLE A;  4KY4 A;  3SRS X;  1RX4 A;  4EIZ A;  3ZPG A;  3DAT A;  6DFR A;  3TQ9 A;  5JG0 X;  3Q1H A;  3FL9 A;  3F0V X;  3RO9 A;  4G3M A;  3KGY A;  1DYJ A;  4M2X A;  5HQZ A;  1PD9 A;  1DYR A;  3IX9 A;  2ZZA A;  4KD7 A;  3D80 A;  1U71 A;  1RX3 A;  1DYI A;  4TU5 X;  3FY8 X;  3UM8 A;  2ITH A;  2OBC A;  1IA2 A;  2HM9 A;  3NZC X;  2W3W A;  1DDS A;  1KLK A;  3FRF X;  4Q0D A;  3ZPC A;  4G8Z X;  4KY8 A;  1PD8 A;  1BZF A;  1DIS A;  3QLR A;  4XRB A;  3FQV A;  4XT8 A;  5FDA A;  3SRR X;  1OHK A;  2JYB A;  1IA4 A;  2W9S A;  3GHC A;  4QLG A;  4P3R A;  1DR5 A; 
#chains in the Genus database with same CATH homology
 1S3W A;  2BLA A;  1DDR A;  2AZN A;  3DL5 A;  3IRO A;  4ELF A;  3NZA X;  4ELG A;  3QL3 A;  4QI9 A;  2BLB A;  2FZJ A;  1DHF A;  2DRC A;  4X5F A;  3TQA A;  3M08 A;  2LF1 A;  3SAI A;  4LAH X;  3S3V A;  1S3Y A;  1DHJ A;  1S3V A;  3SRU X;  3JW3 A;  4LEK X;  3SA1 A;  4KLX A;  1IA3 A;  1DLR A;  8DFR A;  4ELE A;  3INV A;  2W9H A;  4EJ1 A;  5DFR A;  1HFP A;  4X5J A;  3DL6 A;  1KMS A;  1RA3 A;  3NXY A;  2FZH A;  4KAK A;  3CLB A;  5HSU A;  1DG7 A;  1RA9 A;  1BOZ A;  3I3R A;  4FGH A;  1KMV A;  3IA4 A;  1M79 A;  5EAJ A;  1RC4 A;  2W3M A;  3QLS A;  2ANO A;  5HT5 A;  3OAF A;  2HXV A;  1DR7 A;  3EX8 A;  3RG9 A;  3QYO A;  1JOM A;  4FHB A;  1QZF A;  4QJC A;  3F0S X;  4DP3 A;  2G6V A;  2FZI A;  4LAE X;  1DR3 A;  1VJ3 A;  5HSR A;  1AI9 A;  3FRA X;  3FL8 A;  3S7A A;  3JSU A;  3N0H A;  3F91 A;  3ROA A;  3FRB X;  4LAG X;  3SRW X;  4H95 A;  3SA2 A;  1DHI A;  4M7U A;  2HQP A;  1DR2 A;  1DR6 A;  1ZDR A;  3DFR A;  2B3Z A;  4ECK A;  1RA1 A;  3SRQ X;  2KGK A;  4Q6A A;  3FQF A;  4KEB A;  1RF7 A;  1DRB A;  3NXO A;  4FGG A;  4P66 A;  2GD9 A;  4QHV A;  3NZB X;  3FRE X;  1HFR A;  5HF2 X;  4XT5 A;  3EEL A;  5HI6 A;  3GHV A;  3TQB A;  1S3U A;  3CSE A;  5HPB A;  4X5H A;  2OIP A;  3SH2 A;  3JW5 A;  4QJZ D;  3QGT A;  3S9U A;  3FYV X;  4HOF A;  2W9T A;  1U72 A;  1DF7 A;  2DHF A;  3NZD A;  2W3V A;  3QL0 A;  3LG4 A;  3F0Q X;  1PDB A;  3KJR A;  3IRN A;  3IRM A;  1MVT A;  5ECX A;  1DR1 A;  4H98 A;  4H96 A;  3KFY A;  3DGA A;  4KNE A;  3EEM A;  1DR4 A;  2D0K A;  1AO8 A;  1D1G A;  3D84 X;  3KY8 A;  4IXF X;  3UM5 A;  2ANQ A;  1M78 A;  4PDJ A;  3FYW X;  3TQ8 A;  1JUV A;  3SGY A;  1J3I A;  3CL9 A;  2W3B A;  2BLC A;  3E0B A;  1IA1 A;  3FQZ A;  3HBB A;  1RA8 A;  3GHW A;  1VDR A;  4I1N A;  3K47 A;  1DRH A;  1AOE A;  3F0B X;  3DG8 A;  2W9G A;  4KFJ A;  3QLX A;  3F8Z A;  1DLS A;  2W3A A;  3NTZ A;  4M6J A;  1CZ3 A;  3QLY A;  3F0X X;  4HA7 A;  1YHO A;  4PTH A;  1U70 A;  2CD2 A;  3JWK A;  3FY9 X;  4G95 A;  2BL9 A;  4PTJ A;  1MVS A;  2CIG A;  4EIL A;  4HOE A;  4I13 A;  3R33 A;  3UM6 A;  4DFR A;  2O7P A;  1DG5 A;  4M6L A;  4KJL A;  1RD7 A;  3CD2 A;  4PSY A;  3FQ0 A;  3M09 A;  4NX6 A;  4DDR A;  1J3K A;  4KM2 A;  2C2T A;  3GI2 A;  1RG7 A;  3JVX A;  3FRD X;  3TD8 A;  4XT7 A;  4XE6 X;  4KBN A;  7DFR A;  4H97 A;  4XT4 A;  5ECC A;  1M7A A;  3NRR A;  2D5N A;  1RE7 A;  1HFQ A;  5HVB A;  1DAJ A;  4OSG A;  2L28 A;  3NXV A;  5CCC A;  1RA2 A;  3VCO A;  3FS6 A;  4Q0E A;  4DPD A;  3NZ9 X;  3FQC A;  4M6K A;  3QLW A;  5HQY A;  3EIG A;  5U27 A;  1CD2 A;  3K74 A;  1LY4 A;  1DIU A;  3K2H A;  3OCH A;  5U26 A;  1RX6 A;  4HA9 A;  1DRA A;  4OR7 A;  3JWC A;  4IXE D;  1SEJ A;  3HJ3 A;  2H2Q A;  3SQY X;  3GYF A;  5E8Q A;  5DXV A;  4KYA A;  5HF0 X;  5HUI A;  3JWM A;  4DPH A;  1RB2 A;  4QLF A;  1JOL A;  1DRF A;  4CD2 A;  1TDR A;  4PSS A;  1DRE A;  1RX7 A;  3NU0 A;  3NXT A;  3F8Y A;  3IA5 A;  1LY3 A;  1DG8 A;  1RX9 A;  4EIG A;  3K45 A;  3DAU A;  2INQ A;  3NXR A;  4KL9 A;  4RGC A;  4XEC X;  5HT4 A;  4HOG A;  1J3J A;  3FQO A;  3NXX A;  4KJK A;  2QK8 A;  4IXG X;  1RX2 A;  4P68 A;  5CC9 A;  2P4G A;  3QLZ A;  3KJS A;  3JTW A;  1RX8 A;  2C2S A;  4NX7 A;  4ELB A;  3EEK A;  4KJJ A;  3EEJ A;  3NZ6 X;  1RX5 A;  4KM0 A;  3I8A X;  3QG2 A;  4P3Q A;  3F0U X;  1LUD A;  5JA3 A;  3JWF A;  4GH8 A;  3L3R A;  4Q67 A;  4PST A;  3SR5 X;  4ELH A;  1E26 A;  1RH3 A;  4X5G A;  4XT6 A;  4M7V A;  1OHJ A;  3QYL A;  5HVE A;  2XW7 A;  3DRC A;  1RX1 A;  3QFX A;  1DYH A;  1RB3 A;  4X5I A;  4QLE A;  4KY4 A;  3SRS X;  1RX4 A;  4EIZ A;  3ZPG A;  3DAT A;  6DFR A;  3TQ9 A;  5JG0 X;  3Q1H A;  3FL9 A;  3F0V X;  3RO9 A;  4G3M A;  3KGY A;  1DYJ A;  4M2X A;  5HQZ A;  1PD9 A;  1DYR A;  3IX9 A;  2ZZA A;  4KD7 A;  3D80 A;  1U71 A;  1RX3 A;  1DYI A;  4TU5 X;  3FY8 X;  3UM8 A;  2ITH A;  2OBC A;  1IA2 A;  2HM9 A;  3NZC X;  2W3W A;  1DDS A;  1KLK A;  3FRF X;  4Q0D A;  3ZPC A;  4G8Z X;  4KY8 A;  1PD8 A;  1BZF A;  1DIS A;  3QLR A;  4XRB A;  3FQV A;  4XT8 A;  5FDA A;  3SRR X;  1OHK A;  2JYB A;  1IA4 A;  2W9S A;  3GHC A;  4QLG A;  4P3R A;  1DR5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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