3NXVA

Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the e- and z-isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with nadph and human dihydrofolate reductase
Total Genus 57
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Dihydrofolate reductase
total genus 57
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2010-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3nxvA00
3JWFA 3QLYA 1DLRA 3D80A 3QL0A 3QLZA 4FHBA 2HXVA 4ELHA 3SAIA 1RA1A 1RD7A 3EEJA 5E8QA 2W9HA 4X5GA 3NXVA 4ELBA 1CD2A 3NRRA 1PD9A 1RX2A 5HUIA 3UM6A 3QLRA 1D1GA 1RA8A 2W9GA 3DFRA 1VDRA 3SRSX 8DFRA 4P66A 3FRAX 2ZZAA 4I13A 2DHFA 1JUVA 1DLSA 5HQYA 4HOGA 4KM2A 3SRWX 3JSUA 4KJJA 3NXYA 1U72A 4Q67A 4DDRA 1SEJA 5U27A 3NXTA 3SR5X 2HQPA 1OHKA 4ELFA 3CLBA 1M78A 4H96A 2JYBA 4XRBA 2W9TA 1RX4A 1AI9A 4XECX 2BLAA 3F0VX 3OCHA 4KD7A 1RX1A 4Q0EA 3TD8A 2ANOA 2CIGA 3ZPCA 4IXFX 4OR7A 3GI2A 4KFJA 2KGKA 4M7VA 1IA2A 3F8ZA 3QFXA 3DGAA 3FS6A 2C2SA 3F0BX 4NX7A 1RX7A 1DR4A 2W3AA 1DRAA 4RGCA 2W9SA 1IA1A 3M09A 4PSSA 3NZAX 4PTHA 5DXVA 1KMSA 3QLSA 2OBCA 3DL6A 3F91A 3HBBA 2BLBA 2DRCA 3IRMA 3KJSA 1DF7A 3LG4A 1RX5A 4KAKA 5ECCA 3ZPGA 1RG7A 5HVEA 3FL9A 4LAEX 3NZBX 1DR2A 1DYHA 3SH2A 1DHIA 3NZDA 3EX8A 1DRBA 3S7AA 3R33A 2W3MA 1LY3A 3F0SX 1QZFA 3IRNA 3OAFA 3SQYX 3GHWA 1RF7A 1M79A 1HFQA 4X5IA 4M7UA 1RX6A 5CCCA 1DISA 5DFRA 2W3WA 4PSYA 3FQFA 4HOFA 4X5JA 1HFPA 2FZHA 4H98A 3FQZA 5HF2X 4M6KA 1KLKA 2B3ZA 3F0UX 2BL9A 4P3QA 4KY8A 3DG8A 3EELA 3JWKA 4KM0A 1LY4A 3NXOA 4QLGA 3FYWX 1J3IA 1DR3A 3Q1HA 3RG9A 2W3VA 3NXXA 5HPBA 4HA7A 1RC4A 3GHCA 3L3RA 3TQ8A 1RX9A 4QLFA 1OHJA 3FREX 4KLXA 1DHFA 3FYVX 4XT7A 4FGHA 5HT4A 4QJZD 4DPHA 2D0KA 1S3VA 1DRHA 4QI9A 4XE6X 4QLEA 1YHOA 2P4GA 3QGTA 3UM5A 4IXGX 5HT5A 1HFRA 3FL8A 3SA1A 1MVSA 3QYLA 2D5NA 3QLWA 2XW7A 1RB3A 4QHVA 4EILA 2W3BA 3FRDX 4OSGA 1IA3A 3S3VA 1RA9A 1JOMA 3TQBA 4EJ1A 2OIPA 3INVA 4ELEA 1DG8A 3N0HA 3SRUX 3FQCA 2CD2A 4QJCA 1J3JA 4XT8A 1DR6A 3HJ3A 1S3YA 1DR5A 3IROA 1IA4A 1LUDA 3DATA 3I3RA 4DP3A 3I8AX 1DYJA 2LF1A 4NX6A 1RB2A 3NU0A 3KY8A 3NTZA 1AOEA 1M7AA 1JOLA 2QK8A 3CL9A 5U26A 3DRCA 3F0XX 3SRRX 4EIZA 4HA9A 4KY4A 2ANQA 4ECKA 1S3WA 3JW5A 6DFRA 3DAUA 4KJKA 1PD8A 3UM8A 4M6JA 3JVXA 4M2XA 5JG0X 1DR1A 4I1NA 3FQVA 3IA4A 1BZFA 3NZ9X 4Q6AA 3JWMA 2H2QA 4DPDA 2GD9A 3K45A 1MVTA 5HSRA 1BOZA 4XT5A 4H95A 3FQ0A 1DIUA 2G6VA 1J3KA 1RX8A 3K47A 3FRBX 1RH3A 2FZJA 3D84X 1DRFA 5HSUA 3F0QX 4TU5X 1DYIA 3IX9A 4XT6A 4H97A 3JTWA 1VJ3A 5HQZA 2O7PA 2ITHA 4GH8A 2HM9A 4G3MA 4P3RA 1RA2A 3EEMA 4EIGA 4KL9A 4KNEA 2C2TA 4ELGA 3M08A 3IA5A 1KMVA 4KBNA 2L28A 1U70A 3SGYA 5HF0X 4G8ZX 3FY8X 4X5FA 3RO9A 3QYOA 3SRQX 3DL5A 4HOEA 3JWCA 3KJRA 4KYAA 1E26A 5JA3A 4PTJA 4KEBA 1RA3A 4P68A 4CD2A 4LAGX 1CZ3A 2FZIA 4FGGA 1TDRA 3F8YA 1DDSA 2INQA 3QL3A 3CD2A 4PSTA 3KFYA 4PDJA 5ECXA 4Q0DA 5HVBA 4M6LA 1U71A 3NZCX 1DREA 1DG7A 1PDBA 3S9UA 3NXRA 5CC9A 1DR7A 4DFRA 3NZ6X 3FY9X 1RX3A 3E0BA 4XT4A 2AZNA 3K2HA 5HI6A 3EEKA 1DHJA 3GYFA 3ROAA 1DYRA 3JW3A 3K74A 3QLXA 3KGYA 3FRFX 1RE7A 4IXED 7DFRA 1S3UA 3SA2A 1DDRA 3EIGA 1DG5A 4X5HA 5EAJA 3TQ9A 4LAHX 4LEKX 1ZDRA 4KJLA 5FDAA 3FQOA 3QG2A 3CSEA 3GHVA 1DAJA 4G95A 3VCOA 3TQAA 2BLCA 1AO8A
chains in the Genus database with same CATH superfamily
3JWFA 3QLYA 1DLRA 3D80A 3QL0A 3QLZA 4FHBA 2HXVA 4ELHA 3SAIA 1RA1A 1RD7A 3EEJA 5E8QA 2W9HA 4X5GA 3NXVA 4ELBA 1CD2A 3NRRA 1PD9A 1RX2A 5HUIA 3UM6A 3QLRA 1D1GA 1RA8A 2W9GA 3DFRA 1VDRA 3SRSX 8DFRA 4P66A 3FRAX 2ZZAA 4I13A 2DHFA 1JUVA 1DLSA 5HQYA 4HOGA 4KM2A 3SRWX 3JSUA 4KJJA 3NXYA 1U72A 4Q67A 4DDRA 1SEJA 5U27A 3NXTA 3SR5X 2HQPA 1OHKA 4ELFA 3CLBA 1M78A 4H96A 2JYBA 4XRBA 2W9TA 1RX4A 1AI9A 4XECX 2BLAA 3F0VX 3OCHA 4KD7A 1RX1A 4Q0EA 3TD8A 2ANOA 2CIGA 3ZPCA 4IXFX 4OR7A 3GI2A 4KFJA 2KGKA 4M7VA 1IA2A 3F8ZA 3QFXA 3DGAA 3FS6A 2C2SA 3F0BX 4NX7A 1RX7A 1DR4A 2W3AA 1DRAA 4RGCA 2W9SA 1IA1A 3M09A 4PSSA 3NZAX 4PTHA 5DXVA 1KMSA 3QLSA 2OBCA 3DL6A 3F91A 3HBBA 2BLBA 2DRCA 3IRMA 3KJSA 1DF7A 3LG4A 1RX5A 4KAKA 5ECCA 3ZPGA 1RG7A 5HVEA 3FL9A 4LAEX 3NZBX 1DR2A 1DYHA 3SH2A 1DHIA 3NZDA 3EX8A 1DRBA 3S7AA 3R33A 2W3MA 1LY3A 3F0SX 1QZFA 3IRNA 3OAFA 3SQYX 3GHWA 1RF7A 1M79A 1HFQA 4X5IA 4M7UA 1RX6A 5CCCA 1DISA 5DFRA 2W3WA 4PSYA 3FQFA 4HOFA 4X5JA 1HFPA 2FZHA 4H98A 3FQZA 5HF2X 4M6KA 1KLKA 2B3ZA 3F0UX 2BL9A 4P3QA 4KY8A 3DG8A 3EELA 3JWKA 4KM0A 1LY4A 3NXOA 4QLGA 3FYWX 1J3IA 1DR3A 3Q1HA 3RG9A 2W3VA 3NXXA 5HPBA 4HA7A 1RC4A 3GHCA 3L3RA 3TQ8A 1RX9A 4QLFA 1OHJA 3FREX 4KLXA 1DHFA 3FYVX 4XT7A 4FGHA 5HT4A 4QJZD 4DPHA 2D0KA 1S3VA 1DRHA 4QI9A 4XE6X 4QLEA 1YHOA 2P4GA 3QGTA 3UM5A 4IXGX 5HT5A 1HFRA 3FL8A 3SA1A 1MVSA 3QYLA 2D5NA 3QLWA 2XW7A 1RB3A 4QHVA 4EILA 2W3BA 3FRDX 4OSGA 1IA3A 3S3VA 1RA9A 1JOMA 3TQBA 4EJ1A 2OIPA 3INVA 4ELEA 1DG8A 3N0HA 3SRUX 3FQCA 2CD2A 4QJCA 1J3JA 4XT8A 1DR6A 3HJ3A 1S3YA 1DR5A 3IROA 1IA4A 1LUDA 3DATA 3I3RA 4DP3A 3I8AX 1DYJA 2LF1A 4NX6A 1RB2A 3NU0A 3KY8A 3NTZA 1AOEA 1M7AA 1JOLA 2QK8A 3CL9A 5U26A 3DRCA 3F0XX 3SRRX 4EIZA 4HA9A 4KY4A 2ANQA 4ECKA 1S3WA 3JW5A 6DFRA 3DAUA 4KJKA 1PD8A 3UM8A 4M6JA 3JVXA 4M2XA 5JG0X 1DR1A 4I1NA 3FQVA 3IA4A 1BZFA 3NZ9X 4Q6AA 3JWMA 2H2QA 4DPDA 2GD9A 3K45A 1MVTA 5HSRA 1BOZA 4XT5A 4H95A 3FQ0A 1DIUA 2G6VA 1J3KA 1RX8A 3K47A 3FRBX 1RH3A 2FZJA 3D84X 1DRFA 5HSUA 3F0QX 4TU5X 1DYIA 3IX9A 4XT6A 4H97A 3JTWA 1VJ3A 5HQZA 2O7PA 2ITHA 4GH8A 2HM9A 4G3MA 4P3RA 1RA2A 3EEMA 4EIGA 4KL9A 4KNEA 2C2TA 4ELGA 3M08A 3IA5A 1KMVA 4KBNA 2L28A 1U70A 3SGYA 5HF0X 4G8ZX 3FY8X 4X5FA 3RO9A 3QYOA 3SRQX 3DL5A 4HOEA 3JWCA 3KJRA 4KYAA 1E26A 5JA3A 4PTJA 4KEBA 1RA3A 4P68A 4CD2A 4LAGX 1CZ3A 2FZIA 4FGGA 1TDRA 3F8YA 1DDSA 2INQA 3QL3A 3CD2A 4PSTA 3KFYA 4PDJA 5ECXA 4Q0DA 5HVBA 4M6LA 1U71A 3NZCX 1DREA 1DG7A 1PDBA 3S9UA 3NXRA 5CC9A 1DR7A 4DFRA 3NZ6X 3FY9X 1RX3A 3E0BA 4XT4A 2AZNA 3K2HA 5HI6A 3EEKA 1DHJA 3GYFA 3ROAA 1DYRA 3JW3A 3K74A 3QLXA 3KGYA 3FRFX 1RE7A 4IXED 7DFRA 1S3UA 3SA2A 1DDRA 3EIGA 1DG5A 4X5HA 5EAJA 3TQ9A 4LAHX 4LEKX 1ZDRA 4KJLA 5FDAA 3FQOA 3QG2A 3CSEA 3GHVA 1DAJA 4G95A 3VCOA 3TQAA 2BLCA 1AO8A
chains in the Genus database with same CATH topology
3JWFA 3QLYA 1DLRA 3D80A 3QL0A 3QLZA 4FHBA 2HXVA 4ELHA 3SAIA 1RA1A 1RD7A 3EEJA 5E8QA 2W9HA 4X5GA 3NXVA 4ELBA 1CD2A 3NRRA 1PD9A 1RX2A 5HUIA 3UM6A 3QLRA 1D1GA 1RA8A 2W9GA 3DFRA 1VDRA 3SRSX 8DFRA 4P66A 3FRAX 2ZZAA 4I13A 2DHFA 1JUVA 1DLSA 5HQYA 4HOGA 4KM2A 3SRWX 3JSUA 4KJJA 3NXYA 1U72A 4Q67A 4DDRA 1SEJA 5U27A 3NXTA 3SR5X 2HQPA 1OHKA 4ELFA 3CLBA 1M78A 4H96A 2JYBA 4XRBA 2W9TA 1RX4A 1AI9A 4XECX 2BLAA 3F0VX 3OCHA 4KD7A 1RX1A 4Q0EA 3TD8A 2ANOA 2CIGA 3ZPCA 4IXFX 4OR7A 3GI2A 4KFJA 2KGKA 4M7VA 1IA2A 3F8ZA 3QFXA 3DGAA 3FS6A 2C2SA 3F0BX 4NX7A 1RX7A 1DR4A 2W3AA 1DRAA 4RGCA 2W9SA 1IA1A 3M09A 4PSSA 3NZAX 4PTHA 5DXVA 1KMSA 3QLSA 2OBCA 3DL6A 3F91A 3HBBA 2BLBA 2DRCA 3IRMA 3KJSA 1DF7A 3LG4A 1RX5A 4KAKA 5ECCA 3ZPGA 1RG7A 5HVEA 3FL9A 4LAEX 3NZBX 1DR2A 1DYHA 3SH2A 1DHIA 3NZDA 3EX8A 1DRBA 3S7AA 3R33A 2W3MA 1LY3A 3F0SX 1QZFA 3IRNA 3OAFA 3SQYX 3GHWA 1RF7A 1M79A 1HFQA 4X5IA 4M7UA 1RX6A 5CCCA 1DISA 5DFRA 2W3WA 4PSYA 3FQFA 4HOFA 4X5JA 1HFPA 2FZHA 4H98A 3FQZA 5HF2X 4M6KA 1KLKA 2B3ZA 3F0UX 2BL9A 4P3QA 4KY8A 3DG8A 3EELA 3JWKA 4KM0A 1LY4A 3NXOA 4QLGA 3FYWX 1J3IA 1DR3A 3Q1HA 3RG9A 2W3VA 3NXXA 5HPBA 4HA7A 1RC4A 3GHCA 3L3RA 3TQ8A 1RX9A 4QLFA 1OHJA 3FREX 4KLXA 1DHFA 3FYVX 4XT7A 4FGHA 5HT4A 4QJZD 4DPHA 2D0KA 1S3VA 1DRHA 4QI9A 4XE6X 4QLEA 1YHOA 2P4GA 3QGTA 3UM5A 4IXGX 5HT5A 1HFRA 3FL8A 3SA1A 1MVSA 3QYLA 2D5NA 3QLWA 2XW7A 1RB3A 4QHVA 4EILA 2W3BA 3FRDX 4OSGA 1IA3A 3S3VA 1RA9A 1JOMA 3TQBA 4EJ1A 2OIPA 3INVA 4ELEA 1DG8A 3N0HA 3SRUX 3FQCA 2CD2A 4QJCA 1J3JA 4XT8A 1DR6A 3HJ3A 1S3YA 1DR5A 3IROA 1IA4A 1LUDA 3DATA 3I3RA 4DP3A 3I8AX 1DYJA 2LF1A 4NX6A 1RB2A 3NU0A 3KY8A 3NTZA 1AOEA 1M7AA 1JOLA 2QK8A 3CL9A 5U26A 3DRCA 3F0XX 3SRRX 4EIZA 4HA9A 4KY4A 2ANQA 4ECKA 1S3WA 3JW5A 6DFRA 3DAUA 4KJKA 1PD8A 3UM8A 4M6JA 3JVXA 4M2XA 5JG0X 1DR1A 4I1NA 3FQVA 3IA4A 1BZFA 3NZ9X 4Q6AA 3JWMA 2H2QA 4DPDA 2GD9A 3K45A 1MVTA 5HSRA 1BOZA 4XT5A 4H95A 3FQ0A 1DIUA 2G6VA 1J3KA 1RX8A 3K47A 3FRBX 1RH3A 2FZJA 3D84X 1DRFA 5HSUA 3F0QX 4TU5X 1DYIA 3IX9A 4XT6A 4H97A 3JTWA 1VJ3A 5HQZA 2O7PA 2ITHA 4GH8A 2HM9A 4G3MA 4P3RA 1RA2A 3EEMA 4EIGA 4KL9A 4KNEA 2C2TA 4ELGA 3M08A 3IA5A 1KMVA 4KBNA 2L28A 1U70A 3SGYA 5HF0X 4G8ZX 3FY8X 4X5FA 3RO9A 3QYOA 3SRQX 3DL5A 4HOEA 3JWCA 3KJRA 4KYAA 1E26A 5JA3A 4PTJA 4KEBA 1RA3A 4P68A 4CD2A 4LAGX 1CZ3A 2FZIA 4FGGA 1TDRA 3F8YA 1DDSA 2INQA 3QL3A 3CD2A 4PSTA 3KFYA 4PDJA 5ECXA 4Q0DA 5HVBA 4M6LA 1U71A 3NZCX 1DREA 1DG7A 1PDBA 3S9UA 3NXRA 5CC9A 1DR7A 4DFRA 3NZ6X 3FY9X 1RX3A 3E0BA 4XT4A 2AZNA 3K2HA 5HI6A 3EEKA 1DHJA 3GYFA 3ROAA 1DYRA 3JW3A 3K74A 3QLXA 3KGYA 3FRFX 1RE7A 4IXED 7DFRA 1S3UA 3SA2A 1DDRA 3EIGA 1DG5A 4X5HA 5EAJA 3TQ9A 4LAHX 4LEKX 1ZDRA 4KJLA 5FDAA 3FQOA 3QG2A 3CSEA 3GHVA 1DAJA 4G95A 3VCOA 3TQAA 2BLCA 1AO8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JWF A;  3QLY A;  1DLR A;  3D80 A;  3QL0 A;  3QLZ A;  4FHB A;  2HXV A;  4ELH A;  3SAI A;  1RA1 A;  1RD7 A;  3EEJ A;  5E8Q A;  2W9H A;  4X5G A;  3NXV A;  4ELB A;  1CD2 A;  3NRR A;  1PD9 A;  1RX2 A;  5HUI A;  3UM6 A;  3QLR A;  1D1G A;  1RA8 A;  2W9G A;  3DFR A;  1VDR A;  3SRS X;  8DFR A;  4P66 A;  3FRA X;  2ZZA A;  4I13 A;  2DHF A;  1JUV A;  1DLS A;  5HQY A;  4HOG A;  4KM2 A;  3SRW X;  3JSU A;  4KJJ A;  3NXY A;  1U72 A;  4Q67 A;  4DDR A;  1SEJ A;  5U27 A;  3NXT A;  3SR5 X;  2HQP A;  1OHK A;  4ELF A;  3CLB A;  1M78 A;  4H96 A;  2JYB A;  4XRB A;  2W9T A;  1RX4 A;  1AI9 A;  4XEC X;  2BLA A;  3F0V X;  3OCH A;  4KD7 A;  1RX1 A;  4Q0E A;  3TD8 A;  2ANO A;  2CIG A;  3ZPC A;  4IXF X;  4OR7 A;  3GI2 A;  4KFJ A;  2KGK A;  4M7V A;  1IA2 A;  3F8Z A;  3QFX A;  3DGA A;  3FS6 A;  2C2S A;  3F0B X;  4NX7 A;  1RX7 A;  1DR4 A;  2W3A A;  1DRA A;  4RGC A;  2W9S A;  1IA1 A;  3M09 A;  4PSS A;  3NZA X;  4PTH A;  5DXV A;  1KMS A;  3QLS A;  2OBC A;  3DL6 A;  3F91 A;  3HBB A;  2BLB A;  2DRC A;  3IRM A;  3KJS A;  1DF7 A;  3LG4 A;  1RX5 A;  4KAK A;  5ECC A;  3ZPG A;  1RG7 A;  5HVE A;  3FL9 A;  4LAE X;  3NZB X;  1DR2 A;  1DYH A;  3SH2 A;  1DHI A;  3NZD A;  3EX8 A;  1DRB A;  3S7A A;  3R33 A;  2W3M A;  1LY3 A;  3F0S X;  1QZF A;  3IRN A;  3OAF A;  3SQY X;  3GHW A;  1RF7 A;  1M79 A;  1HFQ A;  4X5I A;  4M7U A;  1RX6 A;  5CCC A;  1DIS A;  5DFR A;  2W3W A;  4PSY A;  3FQF A;  4HOF A;  4X5J A;  1HFP A;  2FZH A;  4H98 A;  3FQZ A;  5HF2 X;  4M6K A;  1KLK A;  2B3Z A;  3F0U X;  2BL9 A;  4P3Q A;  4KY8 A;  3DG8 A;  3EEL A;  3JWK A;  4KM0 A;  1LY4 A;  3NXO A;  4QLG A;  3FYW X;  1J3I A;  1DR3 A;  3Q1H A;  3RG9 A;  2W3V A;  3NXX A;  5HPB A;  4HA7 A;  1RC4 A;  3GHC A;  3L3R A;  3TQ8 A;  1RX9 A;  4QLF A;  1OHJ A;  3FRE X;  4KLX A;  1DHF A;  3FYV X;  4XT7 A;  4FGH A;  5HT4 A;  4QJZ D;  4DPH A;  2D0K A;  1S3V A;  1DRH A;  4QI9 A;  4XE6 X;  4QLE A;  1YHO A;  2P4G A;  3QGT A;  3UM5 A;  4IXG X;  5HT5 A;  1HFR A;  3FL8 A;  3SA1 A;  1MVS A;  3QYL A;  2D5N A;  3QLW A;  2XW7 A;  1RB3 A;  4QHV A;  4EIL A;  2W3B A;  3FRD X;  4OSG A;  1IA3 A;  3S3V A;  1RA9 A;  1JOM A;  3TQB A;  4EJ1 A;  2OIP A;  3INV A;  4ELE A;  1DG8 A;  3N0H A;  3SRU X;  3FQC A;  2CD2 A;  4QJC A;  1J3J A;  4XT8 A;  1DR6 A;  3HJ3 A;  1S3Y A;  1DR5 A;  3IRO A;  1IA4 A;  1LUD A;  3DAT A;  3I3R A;  4DP3 A;  3I8A X;  1DYJ A;  2LF1 A;  4NX6 A;  1RB2 A;  3NU0 A;  3KY8 A;  3NTZ A;  1AOE A;  1M7A A;  1JOL A;  2QK8 A;  3CL9 A;  5U26 A;  3DRC A;  3F0X X;  3SRR X;  4EIZ A;  4HA9 A;  4KY4 A;  2ANQ A;  4ECK A;  1S3W A;  3JW5 A;  6DFR A;  3DAU A;  4KJK A;  1PD8 A;  3UM8 A;  4M6J A;  3JVX A;  4M2X A;  5JG0 X;  1DR1 A;  4I1N A;  3FQV A;  3IA4 A;  1BZF A;  3NZ9 X;  4Q6A A;  3JWM A;  2H2Q A;  4DPD A;  2GD9 A;  3K45 A;  1MVT A;  5HSR A;  1BOZ A;  4XT5 A;  4H95 A;  3FQ0 A;  1DIU A;  2G6V A;  1J3K A;  1RX8 A;  3K47 A;  3FRB X;  1RH3 A;  2FZJ A;  3D84 X;  1DRF A;  5HSU A;  3F0Q X;  4TU5 X;  1DYI A;  3IX9 A;  4XT6 A;  4H97 A;  3JTW A;  1VJ3 A;  5HQZ A;  2O7P A;  2ITH A;  4GH8 A;  2HM9 A;  4G3M A;  4P3R A;  1RA2 A;  3EEM A;  4EIG A;  4KL9 A;  4KNE A;  2C2T A;  4ELG A;  3M08 A;  3IA5 A;  1KMV A;  4KBN A;  2L28 A;  1U70 A;  3SGY A;  5HF0 X;  4G8Z X;  3FY8 X;  4X5F A;  3RO9 A;  3QYO A;  3SRQ X;  3DL5 A;  4HOE A;  3JWC A;  3KJR A;  4KYA A;  1E26 A;  5JA3 A;  4PTJ A;  4KEB A;  1RA3 A;  4P68 A;  4CD2 A;  4LAG X;  1CZ3 A;  2FZI A;  4FGG A;  1TDR A;  3F8Y A;  1DDS A;  2INQ A;  3QL3 A;  3CD2 A;  4PST A;  3KFY A;  4PDJ A;  5ECX A;  4Q0D A;  5HVB A;  4M6L A;  1U71 A;  3NZC X;  1DRE A;  1DG7 A;  1PDB A;  3S9U A;  3NXR A;  5CC9 A;  1DR7 A;  4DFR A;  3NZ6 X;  3FY9 X;  1RX3 A;  3E0B A;  4XT4 A;  2AZN A;  3K2H A;  5HI6 A;  3EEK A;  1DHJ A;  3GYF A;  3ROA A;  1DYR A;  3JW3 A;  3K74 A;  3QLX A;  3KGY A;  3FRF X;  1RE7 A;  4IXE D;  7DFR A;  1S3U A;  3SA2 A;  1DDR A;  3EIG A;  1DG5 A;  4X5H A;  5EAJ A;  3TQ9 A;  4LAH X;  4LEK X;  1ZDR A;  4KJL A;  5FDA A;  3FQO A;  3QG2 A;  3CSE A;  3GHV A;  1DAJ A;  4G95 A;  3VCO A;  3TQA A;  2BLC A;  1AO8 A; 
#chains in the Genus database with same CATH topology
 3JWF A;  3QLY A;  1DLR A;  3D80 A;  3QL0 A;  3QLZ A;  4FHB A;  2HXV A;  4ELH A;  3SAI A;  1RA1 A;  1RD7 A;  3EEJ A;  5E8Q A;  2W9H A;  4X5G A;  3NXV A;  4ELB A;  1CD2 A;  3NRR A;  1PD9 A;  1RX2 A;  5HUI A;  3UM6 A;  3QLR A;  1D1G A;  1RA8 A;  2W9G A;  3DFR A;  1VDR A;  3SRS X;  8DFR A;  4P66 A;  3FRA X;  2ZZA A;  4I13 A;  2DHF A;  1JUV A;  1DLS A;  5HQY A;  4HOG A;  4KM2 A;  3SRW X;  3JSU A;  4KJJ A;  3NXY A;  1U72 A;  4Q67 A;  4DDR A;  1SEJ A;  5U27 A;  3NXT A;  3SR5 X;  2HQP A;  1OHK A;  4ELF A;  3CLB A;  1M78 A;  4H96 A;  2JYB A;  4XRB A;  2W9T A;  1RX4 A;  1AI9 A;  4XEC X;  2BLA A;  3F0V X;  3OCH A;  4KD7 A;  1RX1 A;  4Q0E A;  3TD8 A;  2ANO A;  2CIG A;  3ZPC A;  4IXF X;  4OR7 A;  3GI2 A;  4KFJ A;  2KGK A;  4M7V A;  1IA2 A;  3F8Z A;  3QFX A;  3DGA A;  3FS6 A;  2C2S A;  3F0B X;  4NX7 A;  1RX7 A;  1DR4 A;  2W3A A;  1DRA A;  4RGC A;  2W9S A;  1IA1 A;  3M09 A;  4PSS A;  3NZA X;  4PTH A;  5DXV A;  1KMS A;  3QLS A;  2OBC A;  3DL6 A;  3F91 A;  3HBB A;  2BLB A;  2DRC A;  3IRM A;  3KJS A;  1DF7 A;  3LG4 A;  1RX5 A;  4KAK A;  5ECC A;  3ZPG A;  1RG7 A;  5HVE A;  3FL9 A;  4LAE X;  3NZB X;  1DR2 A;  1DYH A;  3SH2 A;  1DHI A;  3NZD A;  3EX8 A;  1DRB A;  3S7A A;  3R33 A;  2W3M A;  1LY3 A;  3F0S X;  1QZF A;  3IRN A;  3OAF A;  3SQY X;  3GHW A;  1RF7 A;  1M79 A;  1HFQ A;  4X5I A;  4M7U A;  1RX6 A;  5CCC A;  1DIS A;  5DFR A;  2W3W A;  4PSY A;  3FQF A;  4HOF A;  4X5J A;  1HFP A;  2FZH A;  4H98 A;  3FQZ A;  5HF2 X;  4M6K A;  1KLK A;  2B3Z A;  3F0U X;  2BL9 A;  4P3Q A;  4KY8 A;  3DG8 A;  3EEL A;  3JWK A;  4KM0 A;  1LY4 A;  3NXO A;  4QLG A;  3FYW X;  1J3I A;  1DR3 A;  3Q1H A;  3RG9 A;  2W3V A;  3NXX A;  5HPB A;  4HA7 A;  1RC4 A;  3GHC A;  3L3R A;  3TQ8 A;  1RX9 A;  4QLF A;  1OHJ A;  3FRE X;  4KLX A;  1DHF A;  3FYV X;  4XT7 A;  4FGH A;  5HT4 A;  4QJZ D;  4DPH A;  2D0K A;  1S3V A;  1DRH A;  4QI9 A;  4XE6 X;  4QLE A;  1YHO A;  2P4G A;  3QGT A;  3UM5 A;  4IXG X;  5HT5 A;  1HFR A;  3FL8 A;  3SA1 A;  1MVS A;  3QYL A;  2D5N A;  3QLW A;  2XW7 A;  1RB3 A;  4QHV A;  4EIL A;  2W3B A;  3FRD X;  4OSG A;  1IA3 A;  3S3V A;  1RA9 A;  1JOM A;  3TQB A;  4EJ1 A;  2OIP A;  3INV A;  4ELE A;  1DG8 A;  3N0H A;  3SRU X;  3FQC A;  2CD2 A;  4QJC A;  1J3J A;  4XT8 A;  1DR6 A;  3HJ3 A;  1S3Y A;  1DR5 A;  3IRO A;  1IA4 A;  1LUD A;  3DAT A;  3I3R A;  4DP3 A;  3I8A X;  1DYJ A;  2LF1 A;  4NX6 A;  1RB2 A;  3NU0 A;  3KY8 A;  3NTZ A;  1AOE A;  1M7A A;  1JOL A;  2QK8 A;  3CL9 A;  5U26 A;  3DRC A;  3F0X X;  3SRR X;  4EIZ A;  4HA9 A;  4KY4 A;  2ANQ A;  4ECK A;  1S3W A;  3JW5 A;  6DFR A;  3DAU A;  4KJK A;  1PD8 A;  3UM8 A;  4M6J A;  3JVX A;  4M2X A;  5JG0 X;  1DR1 A;  4I1N A;  3FQV A;  3IA4 A;  1BZF A;  3NZ9 X;  4Q6A A;  3JWM A;  2H2Q A;  4DPD A;  2GD9 A;  3K45 A;  1MVT A;  5HSR A;  1BOZ A;  4XT5 A;  4H95 A;  3FQ0 A;  1DIU A;  2G6V A;  1J3K A;  1RX8 A;  3K47 A;  3FRB X;  1RH3 A;  2FZJ A;  3D84 X;  1DRF A;  5HSU A;  3F0Q X;  4TU5 X;  1DYI A;  3IX9 A;  4XT6 A;  4H97 A;  3JTW A;  1VJ3 A;  5HQZ A;  2O7P A;  2ITH A;  4GH8 A;  2HM9 A;  4G3M A;  4P3R A;  1RA2 A;  3EEM A;  4EIG A;  4KL9 A;  4KNE A;  2C2T A;  4ELG A;  3M08 A;  3IA5 A;  1KMV A;  4KBN A;  2L28 A;  1U70 A;  3SGY A;  5HF0 X;  4G8Z X;  3FY8 X;  4X5F A;  3RO9 A;  3QYO A;  3SRQ X;  3DL5 A;  4HOE A;  3JWC A;  3KJR A;  4KYA A;  1E26 A;  5JA3 A;  4PTJ A;  4KEB A;  1RA3 A;  4P68 A;  4CD2 A;  4LAG X;  1CZ3 A;  2FZI A;  4FGG A;  1TDR A;  3F8Y A;  1DDS A;  2INQ A;  3QL3 A;  3CD2 A;  4PST A;  3KFY A;  4PDJ A;  5ECX A;  4Q0D A;  5HVB A;  4M6L A;  1U71 A;  3NZC X;  1DRE A;  1DG7 A;  1PDB A;  3S9U A;  3NXR A;  5CC9 A;  1DR7 A;  4DFR A;  3NZ6 X;  3FY9 X;  1RX3 A;  3E0B A;  4XT4 A;  2AZN A;  3K2H A;  5HI6 A;  3EEK A;  1DHJ A;  3GYF A;  3ROA A;  1DYR A;  3JW3 A;  3K74 A;  3QLX A;  3KGY A;  3FRF X;  1RE7 A;  4IXE D;  7DFR A;  1S3U A;  3SA2 A;  1DDR A;  3EIG A;  1DG5 A;  4X5H A;  5EAJ A;  3TQ9 A;  4LAH X;  4LEK X;  1ZDR A;  4KJL A;  5FDA A;  3FQO A;  3QG2 A;  3CSE A;  3GHV A;  1DAJ A;  4G95 A;  3VCO A;  3TQA A;  2BLC A;  1AO8 A; 
#chains in the Genus database with same CATH homology
 3JWF A;  3QLY A;  1DLR A;  3D80 A;  3QL0 A;  3QLZ A;  4FHB A;  2HXV A;  4ELH A;  3SAI A;  1RA1 A;  1RD7 A;  3EEJ A;  5E8Q A;  2W9H A;  4X5G A;  3NXV A;  4ELB A;  1CD2 A;  3NRR A;  1PD9 A;  1RX2 A;  5HUI A;  3UM6 A;  3QLR A;  1D1G A;  1RA8 A;  2W9G A;  3DFR A;  1VDR A;  3SRS X;  8DFR A;  4P66 A;  3FRA X;  2ZZA A;  4I13 A;  2DHF A;  1JUV A;  1DLS A;  5HQY A;  4HOG A;  4KM2 A;  3SRW X;  3JSU A;  4KJJ A;  3NXY A;  1U72 A;  4Q67 A;  4DDR A;  1SEJ A;  5U27 A;  3NXT A;  3SR5 X;  2HQP A;  1OHK A;  4ELF A;  3CLB A;  1M78 A;  4H96 A;  2JYB A;  4XRB A;  2W9T A;  1RX4 A;  1AI9 A;  4XEC X;  2BLA A;  3F0V X;  3OCH A;  4KD7 A;  1RX1 A;  4Q0E A;  3TD8 A;  2ANO A;  2CIG A;  3ZPC A;  4IXF X;  4OR7 A;  3GI2 A;  4KFJ A;  2KGK A;  4M7V A;  1IA2 A;  3F8Z A;  3QFX A;  3DGA A;  3FS6 A;  2C2S A;  3F0B X;  4NX7 A;  1RX7 A;  1DR4 A;  2W3A A;  1DRA A;  4RGC A;  2W9S A;  1IA1 A;  3M09 A;  4PSS A;  3NZA X;  4PTH A;  5DXV A;  1KMS A;  3QLS A;  2OBC A;  3DL6 A;  3F91 A;  3HBB A;  2BLB A;  2DRC A;  3IRM A;  3KJS A;  1DF7 A;  3LG4 A;  1RX5 A;  4KAK A;  5ECC A;  3ZPG A;  1RG7 A;  5HVE A;  3FL9 A;  4LAE X;  3NZB X;  1DR2 A;  1DYH A;  3SH2 A;  1DHI A;  3NZD A;  3EX8 A;  1DRB A;  3S7A A;  3R33 A;  2W3M A;  1LY3 A;  3F0S X;  1QZF A;  3IRN A;  3OAF A;  3SQY X;  3GHW A;  1RF7 A;  1M79 A;  1HFQ A;  4X5I A;  4M7U A;  1RX6 A;  5CCC A;  1DIS A;  5DFR A;  2W3W A;  4PSY A;  3FQF A;  4HOF A;  4X5J A;  1HFP A;  2FZH A;  4H98 A;  3FQZ A;  5HF2 X;  4M6K A;  1KLK A;  2B3Z A;  3F0U X;  2BL9 A;  4P3Q A;  4KY8 A;  3DG8 A;  3EEL A;  3JWK A;  4KM0 A;  1LY4 A;  3NXO A;  4QLG A;  3FYW X;  1J3I A;  1DR3 A;  3Q1H A;  3RG9 A;  2W3V A;  3NXX A;  5HPB A;  4HA7 A;  1RC4 A;  3GHC A;  3L3R A;  3TQ8 A;  1RX9 A;  4QLF A;  1OHJ A;  3FRE X;  4KLX A;  1DHF A;  3FYV X;  4XT7 A;  4FGH A;  5HT4 A;  4QJZ D;  4DPH A;  2D0K A;  1S3V A;  1DRH A;  4QI9 A;  4XE6 X;  4QLE A;  1YHO A;  2P4G A;  3QGT A;  3UM5 A;  4IXG X;  5HT5 A;  1HFR A;  3FL8 A;  3SA1 A;  1MVS A;  3QYL A;  2D5N A;  3QLW A;  2XW7 A;  1RB3 A;  4QHV A;  4EIL A;  2W3B A;  3FRD X;  4OSG A;  1IA3 A;  3S3V A;  1RA9 A;  1JOM A;  3TQB A;  4EJ1 A;  2OIP A;  3INV A;  4ELE A;  1DG8 A;  3N0H A;  3SRU X;  3FQC A;  2CD2 A;  4QJC A;  1J3J A;  4XT8 A;  1DR6 A;  3HJ3 A;  1S3Y A;  1DR5 A;  3IRO A;  1IA4 A;  1LUD A;  3DAT A;  3I3R A;  4DP3 A;  3I8A X;  1DYJ A;  2LF1 A;  4NX6 A;  1RB2 A;  3NU0 A;  3KY8 A;  3NTZ A;  1AOE A;  1M7A A;  1JOL A;  2QK8 A;  3CL9 A;  5U26 A;  3DRC A;  3F0X X;  3SRR X;  4EIZ A;  4HA9 A;  4KY4 A;  2ANQ A;  4ECK A;  1S3W A;  3JW5 A;  6DFR A;  3DAU A;  4KJK A;  1PD8 A;  3UM8 A;  4M6J A;  3JVX A;  4M2X A;  5JG0 X;  1DR1 A;  4I1N A;  3FQV A;  3IA4 A;  1BZF A;  3NZ9 X;  4Q6A A;  3JWM A;  2H2Q A;  4DPD A;  2GD9 A;  3K45 A;  1MVT A;  5HSR A;  1BOZ A;  4XT5 A;  4H95 A;  3FQ0 A;  1DIU A;  2G6V A;  1J3K A;  1RX8 A;  3K47 A;  3FRB X;  1RH3 A;  2FZJ A;  3D84 X;  1DRF A;  5HSU A;  3F0Q X;  4TU5 X;  1DYI A;  3IX9 A;  4XT6 A;  4H97 A;  3JTW A;  1VJ3 A;  5HQZ A;  2O7P A;  2ITH A;  4GH8 A;  2HM9 A;  4G3M A;  4P3R A;  1RA2 A;  3EEM A;  4EIG A;  4KL9 A;  4KNE A;  2C2T A;  4ELG A;  3M08 A;  3IA5 A;  1KMV A;  4KBN A;  2L28 A;  1U70 A;  3SGY A;  5HF0 X;  4G8Z X;  3FY8 X;  4X5F A;  3RO9 A;  3QYO A;  3SRQ X;  3DL5 A;  4HOE A;  3JWC A;  3KJR A;  4KYA A;  1E26 A;  5JA3 A;  4PTJ A;  4KEB A;  1RA3 A;  4P68 A;  4CD2 A;  4LAG X;  1CZ3 A;  2FZI A;  4FGG A;  1TDR A;  3F8Y A;  1DDS A;  2INQ A;  3QL3 A;  3CD2 A;  4PST A;  3KFY A;  4PDJ A;  5ECX A;  4Q0D A;  5HVB A;  4M6L A;  1U71 A;  3NZC X;  1DRE A;  1DG7 A;  1PDB A;  3S9U A;  3NXR A;  5CC9 A;  1DR7 A;  4DFR A;  3NZ6 X;  3FY9 X;  1RX3 A;  3E0B A;  4XT4 A;  2AZN A;  3K2H A;  5HI6 A;  3EEK A;  1DHJ A;  3GYF A;  3ROA A;  1DYR A;  3JW3 A;  3K74 A;  3QLX A;  3KGY A;  3FRF X;  1RE7 A;  4IXE D;  7DFR A;  1S3U A;  3SA2 A;  1DDR A;  3EIG A;  1DG5 A;  4X5H A;  5EAJ A;  3TQ9 A;  4LAH X;  4LEK X;  1ZDR A;  4KJL A;  5FDA A;  3FQO A;  3QG2 A;  3CSE A;  3GHV A;  1DAJ A;  4G95 A;  3VCO A;  3TQA A;  2BLC A;  1AO8 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...