3NZBX

Structural analysis of pneumocystis carinii and human dhfr complexes with nadph and a series of potent 5-(omega-carboxyl(alkyloxy)pyrido[2,-d]pyrimidine derivatives
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
206
structure length
206
Chain Sequence
MNQQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQFRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-([omega]-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Pneumocystis carinii
molecule keywords Dihydrofolate reductase
total genus 57
structure length 206
sequence length 206
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3nzbX00
3FQ0A 4IXGX 1DR7A 4KLXA 2W3MA 4KM0A 3SR5X 4H98A 3I8AX 5CC9A 2B3ZA 3CD2A 3F0SX 1D1GA 1RA3A 4M7VA 4X5IA 2GD9A 4KJKA 3F0UX 3KGYA 1DF7A 2BLBA 1PD8A 5CCCA 1AO8A 4X5GA 2HQPA 3EIGA 3FREX 1U70A 1DISA 1J3KA 4FGHA 4EILA 5HUIA 1BOZA 5HVBA 3SH2A 3CLBA 3F8YA 4M6LA 1DR5A 1S3WA 1PDBA 4QHVA 3DATA 2W3WA 3CL9A 2OBCA 3FQOA 3NXVA 3IX9A 3F8ZA 1DDSA 5HT4A 4DPDA 1VDRA 1RX2A 1RX3A 1OHJA 4KJJA 2C2TA 1JOLA 3JWMA 1HFQA 1DHIA 4P3QA 1DR2A 2L28A 3QLZA 2QK8A 3FY8X 5EAJA 1DYHA 2BL9A 3DAUA 4HA7A 5DXVA 4Q0DA 2W9GA 4ELFA 4LAHX 3TQ9A 4KD7A 3JSUA 4KYAA 2W9SA 3EEKA 3Q1HA 3TD8A 1QZFA 3SA2A 4M6JA 4KFJA 3K74A 1M78A 6DFRA 4Q6AA 4KL9A 3KJRA 1RX5A 1DRAA 2H2QA 1LUDA 1JOMA 3GHCA 4HOGA 4Q67A 3NXTA 4G95A 4NX7A 3SRQX 3FRDX 3QLWA 3VCOA 1DG8A 5ECCA 3IA4A 3UM6A 1CD2A 3FQCA 3EELA 4P66A 5HVEA 3OCHA 1LY3A 3N0HA 4XT7A 1BZFA 5ECXA 1DHFA 1DG5A 1RC4A 3JTWA 4KNEA 3FY9X 4G8ZX 3QFXA 5HT5A 4XT5A 4OSGA 2W3BA 8DFRA 4TU5X 5HQYA 4XT8A 4HOFA 2FZHA 3FL9A 4QLGA 3SQYX 4HOEA 3QLSA 1RG7A 3DL5A 4PSSA 4ELEA 3S7AA 1DG7A 4KEBA 3D84X 4QLFA 5DFRA 2JYBA 2W9TA 1JUVA 3D80A 3DG8A 1U72A 3F0XX 3SRRX 3NXXA 1YHOA 3K2HA 7DFRA 2C2SA 4PSTA 4PTHA 5HF2X 3S9UA 1DYIA 1RA9A 3JW3A 1DRHA 1RH3A 1RX1A 4KM2A 2W3AA 4IXED 3SRSX 1ZDRA 1RE7A 4KBNA 3SA1A 3F91A 4GH8A 1IA3A 1HFPA 3M09A 3TQAA 1RB3A 2DRCA 2INQA 1S3UA 4KY8A 1SEJA 4M6KA 4ELBA 4XT6A 5HSUA 4G3MA 5E8QA 4ELGA 1LY4A 3NZCX 1RA8A 5JG0X 4RGCA 1DRBA 4KJLA 5U27A 3JWKA 3FQZA 3NXRA 4X5FA 4IXFX 3KY8A 3NZBX 4KY4A 4QJZD 1S3YA 4M7UA 3DFRA 3TQ8A 2XW7A 3IRMA 3IRNA 4ELHA 3K45A 3QLXA 3R33A 2KGKA 4PDJA 3TQBA 4EJ1A 4QJCA 4P3RA 3M08A 3F0BX 5HPBA 4PSYA 1AI9A 3EEMA 3NZ6X 1RX9A 1RX7A 3IROA 5HSRA 3RG9A 4NX6A 1M7AA 3QL0A 1RA1A 3FQVA 5JA3A 2W9HA 3KJSA 1M79A 4CD2A 4FHBA 1DAJA 1S3VA 3ZPGA 3FYWX 1IA4A 2G6VA 2HM9A 4DDRA 2ANQA 2BLCA 2ZZAA 3E0BA 1RX8A 3NZAX 4H97A 1DHJA 1RX4A 3HJ3A 4QI9A 1IA2A 2OIPA 4QLEA 2BLAA 1DR4A 5HF0X 1DREA 3QLYA 2LF1A 3QL3A 3DRCA 1CZ3A 4EIZA 1RD7A 1KMVA 3DL6A 4Q0EA 3NZDA 3EEJA 3RO9A 1PD9A 5HI6A 3SGYA 1U71A 2FZJA 3SRUX 3JWCA 3NZ9X 3I3RA 3FRBX 1DYRA 3FS6A 3QGTA 3GHWA 4OR7A 1DR6A 1DRFA 1DIUA 3L3RA 4HA9A 4X5JA 4I13A 2AZNA 1KMSA 3FL8A 2CD2A 3KFYA 3QYOA 3NXOA 3NTZA 3SRWX 3UM5A 3QG2A 3ZPCA 1MVTA 4XRBA 1KLKA 1DR3A 3FYVX 2CIGA 4LAEX 3EX8A 4ECKA 3F0VX 2HXVA 3SAIA 3FQFA 3FRFX 2FZIA 3IA5A 1RA2A 3LG4A 1HFRA 2W3VA 4LEKX 4DP3A 1MVSA 4H96A 1TDRA 3GHVA 4DPHA 3INVA 3OAFA 4I1NA 4DFRA 1DYJA 1RB2A 3DGAA 4P68A 3HBBA 3QYLA 5FDAA 4EIGA 3K47A 4M2XA 2DHFA 3ROAA 3CSEA 3FRAX 3NRRA 3S3VA 3GI2A 1J3IA 3JWFA 1DLRA 3QLRA 3NXYA 2D0KA 2ANOA 4FGGA 5U26A 1IA1A 2ITHA 2D5NA 1RF7A 4KAKA 4XECX 4H95A 3NU0A 3F0QX 3UM8A 2P4GA 3JVXA 1OHKA 1VJ3A 4LAGX 5HQZA 3JW5A 4X5HA 1RX6A 4XE6X 4PTJA 1DLSA 1E26A 1AOEA 2O7PA 4XT4A 1DR1A 1J3JA 3GYFA 1DDRA
chains in the Genus database with same CATH superfamily
3FQ0A 4IXGX 1DR7A 4KLXA 2W3MA 4KM0A 3SR5X 4H98A 3I8AX 5CC9A 2B3ZA 3CD2A 3F0SX 1D1GA 1RA3A 4M7VA 4X5IA 2GD9A 4KJKA 3F0UX 3KGYA 1DF7A 2BLBA 1PD8A 5CCCA 1AO8A 4X5GA 2HQPA 3EIGA 3FREX 1U70A 1DISA 1J3KA 4FGHA 4EILA 5HUIA 1BOZA 5HVBA 3SH2A 3CLBA 3F8YA 4M6LA 1DR5A 1S3WA 1PDBA 4QHVA 3DATA 2W3WA 3CL9A 2OBCA 3FQOA 3NXVA 3IX9A 3F8ZA 1DDSA 5HT4A 4DPDA 1VDRA 1RX2A 1RX3A 1OHJA 4KJJA 2C2TA 1JOLA 3JWMA 1HFQA 1DHIA 4P3QA 1DR2A 2L28A 3QLZA 2QK8A 3FY8X 5EAJA 1DYHA 2BL9A 3DAUA 4HA7A 5DXVA 4Q0DA 2W9GA 4ELFA 4LAHX 3TQ9A 4KD7A 3JSUA 4KYAA 2W9SA 3EEKA 3Q1HA 3TD8A 1QZFA 3SA2A 4M6JA 4KFJA 3K74A 1M78A 6DFRA 4Q6AA 4KL9A 3KJRA 1RX5A 1DRAA 2H2QA 1LUDA 1JOMA 3GHCA 4HOGA 4Q67A 3NXTA 4G95A 4NX7A 3SRQX 3FRDX 3QLWA 3VCOA 1DG8A 5ECCA 3IA4A 3UM6A 1CD2A 3FQCA 3EELA 4P66A 5HVEA 3OCHA 1LY3A 3N0HA 4XT7A 1BZFA 5ECXA 1DHFA 1DG5A 1RC4A 3JTWA 4KNEA 3FY9X 4G8ZX 3QFXA 5HT5A 4XT5A 4OSGA 2W3BA 8DFRA 4TU5X 5HQYA 4XT8A 4HOFA 2FZHA 3FL9A 4QLGA 3SQYX 4HOEA 3QLSA 1RG7A 3DL5A 4PSSA 4ELEA 3S7AA 1DG7A 4KEBA 3D84X 4QLFA 5DFRA 2JYBA 2W9TA 1JUVA 3D80A 3DG8A 1U72A 3F0XX 3SRRX 3NXXA 1YHOA 3K2HA 7DFRA 2C2SA 4PSTA 4PTHA 5HF2X 3S9UA 1DYIA 1RA9A 3JW3A 1DRHA 1RH3A 1RX1A 4KM2A 2W3AA 4IXED 3SRSX 1ZDRA 1RE7A 4KBNA 3SA1A 3F91A 4GH8A 1IA3A 1HFPA 3M09A 3TQAA 1RB3A 2DRCA 2INQA 1S3UA 4KY8A 1SEJA 4M6KA 4ELBA 4XT6A 5HSUA 4G3MA 5E8QA 4ELGA 1LY4A 3NZCX 1RA8A 5JG0X 4RGCA 1DRBA 4KJLA 5U27A 3JWKA 3FQZA 3NXRA 4X5FA 4IXFX 3KY8A 3NZBX 4KY4A 4QJZD 1S3YA 4M7UA 3DFRA 3TQ8A 2XW7A 3IRMA 3IRNA 4ELHA 3K45A 3QLXA 3R33A 2KGKA 4PDJA 3TQBA 4EJ1A 4QJCA 4P3RA 3M08A 3F0BX 5HPBA 4PSYA 1AI9A 3EEMA 3NZ6X 1RX9A 1RX7A 3IROA 5HSRA 3RG9A 4NX6A 1M7AA 3QL0A 1RA1A 3FQVA 5JA3A 2W9HA 3KJSA 1M79A 4CD2A 4FHBA 1DAJA 1S3VA 3ZPGA 3FYWX 1IA4A 2G6VA 2HM9A 4DDRA 2ANQA 2BLCA 2ZZAA 3E0BA 1RX8A 3NZAX 4H97A 1DHJA 1RX4A 3HJ3A 4QI9A 1IA2A 2OIPA 4QLEA 2BLAA 1DR4A 5HF0X 1DREA 3QLYA 2LF1A 3QL3A 3DRCA 1CZ3A 4EIZA 1RD7A 1KMVA 3DL6A 4Q0EA 3NZDA 3EEJA 3RO9A 1PD9A 5HI6A 3SGYA 1U71A 2FZJA 3SRUX 3JWCA 3NZ9X 3I3RA 3FRBX 1DYRA 3FS6A 3QGTA 3GHWA 4OR7A 1DR6A 1DRFA 1DIUA 3L3RA 4HA9A 4X5JA 4I13A 2AZNA 1KMSA 3FL8A 2CD2A 3KFYA 3QYOA 3NXOA 3NTZA 3SRWX 3UM5A 3QG2A 3ZPCA 1MVTA 4XRBA 1KLKA 1DR3A 3FYVX 2CIGA 4LAEX 3EX8A 4ECKA 3F0VX 2HXVA 3SAIA 3FQFA 3FRFX 2FZIA 3IA5A 1RA2A 3LG4A 1HFRA 2W3VA 4LEKX 4DP3A 1MVSA 4H96A 1TDRA 3GHVA 4DPHA 3INVA 3OAFA 4I1NA 4DFRA 1DYJA 1RB2A 3DGAA 4P68A 3HBBA 3QYLA 5FDAA 4EIGA 3K47A 4M2XA 2DHFA 3ROAA 3CSEA 3FRAX 3NRRA 3S3VA 3GI2A 1J3IA 3JWFA 1DLRA 3QLRA 3NXYA 2D0KA 2ANOA 4FGGA 5U26A 1IA1A 2ITHA 2D5NA 1RF7A 4KAKA 4XECX 4H95A 3NU0A 3F0QX 3UM8A 2P4GA 3JVXA 1OHKA 1VJ3A 4LAGX 5HQZA 3JW5A 4X5HA 1RX6A 4XE6X 4PTJA 1DLSA 1E26A 1AOEA 2O7PA 4XT4A 1DR1A 1J3JA 3GYFA 1DDRA
chains in the Genus database with same CATH topology
3FQ0A 4IXGX 1DR7A 4KLXA 2W3MA 4KM0A 3SR5X 4H98A 3I8AX 5CC9A 2B3ZA 3CD2A 3F0SX 1D1GA 1RA3A 4M7VA 4X5IA 2GD9A 4KJKA 3F0UX 3KGYA 1DF7A 2BLBA 1PD8A 5CCCA 1AO8A 4X5GA 2HQPA 3EIGA 3FREX 1U70A 1DISA 1J3KA 4FGHA 4EILA 5HUIA 1BOZA 5HVBA 3SH2A 3CLBA 3F8YA 4M6LA 1DR5A 1S3WA 1PDBA 4QHVA 3DATA 2W3WA 3CL9A 2OBCA 3FQOA 3NXVA 3IX9A 3F8ZA 1DDSA 5HT4A 4DPDA 1VDRA 1RX2A 1RX3A 1OHJA 4KJJA 2C2TA 1JOLA 3JWMA 1HFQA 1DHIA 4P3QA 1DR2A 2L28A 3QLZA 2QK8A 3FY8X 5EAJA 1DYHA 2BL9A 3DAUA 4HA7A 5DXVA 4Q0DA 2W9GA 4ELFA 4LAHX 3TQ9A 4KD7A 3JSUA 4KYAA 2W9SA 3EEKA 3Q1HA 3TD8A 1QZFA 3SA2A 4M6JA 4KFJA 3K74A 1M78A 6DFRA 4Q6AA 4KL9A 3KJRA 1RX5A 1DRAA 2H2QA 1LUDA 1JOMA 3GHCA 4HOGA 4Q67A 3NXTA 4G95A 4NX7A 3SRQX 3FRDX 3QLWA 3VCOA 1DG8A 5ECCA 3IA4A 3UM6A 1CD2A 3FQCA 3EELA 4P66A 5HVEA 3OCHA 1LY3A 3N0HA 4XT7A 1BZFA 5ECXA 1DHFA 1DG5A 1RC4A 3JTWA 4KNEA 3FY9X 4G8ZX 3QFXA 5HT5A 4XT5A 4OSGA 2W3BA 8DFRA 4TU5X 5HQYA 4XT8A 4HOFA 2FZHA 3FL9A 4QLGA 3SQYX 4HOEA 3QLSA 1RG7A 3DL5A 4PSSA 4ELEA 3S7AA 1DG7A 4KEBA 3D84X 4QLFA 5DFRA 2JYBA 2W9TA 1JUVA 3D80A 3DG8A 1U72A 3F0XX 3SRRX 3NXXA 1YHOA 3K2HA 7DFRA 2C2SA 4PSTA 4PTHA 5HF2X 3S9UA 1DYIA 1RA9A 3JW3A 1DRHA 1RH3A 1RX1A 4KM2A 2W3AA 4IXED 3SRSX 1ZDRA 1RE7A 4KBNA 3SA1A 3F91A 4GH8A 1IA3A 1HFPA 3M09A 3TQAA 1RB3A 2DRCA 2INQA 1S3UA 4KY8A 1SEJA 4M6KA 4ELBA 4XT6A 5HSUA 4G3MA 5E8QA 4ELGA 1LY4A 3NZCX 1RA8A 5JG0X 4RGCA 1DRBA 4KJLA 5U27A 3JWKA 3FQZA 3NXRA 4X5FA 4IXFX 3KY8A 3NZBX 4KY4A 4QJZD 1S3YA 4M7UA 3DFRA 3TQ8A 2XW7A 3IRMA 3IRNA 4ELHA 3K45A 3QLXA 3R33A 2KGKA 4PDJA 3TQBA 4EJ1A 4QJCA 4P3RA 3M08A 3F0BX 5HPBA 4PSYA 1AI9A 3EEMA 3NZ6X 1RX9A 1RX7A 3IROA 5HSRA 3RG9A 4NX6A 1M7AA 3QL0A 1RA1A 3FQVA 5JA3A 2W9HA 3KJSA 1M79A 4CD2A 4FHBA 1DAJA 1S3VA 3ZPGA 3FYWX 1IA4A 2G6VA 2HM9A 4DDRA 2ANQA 2BLCA 2ZZAA 3E0BA 1RX8A 3NZAX 4H97A 1DHJA 1RX4A 3HJ3A 4QI9A 1IA2A 2OIPA 4QLEA 2BLAA 1DR4A 5HF0X 1DREA 3QLYA 2LF1A 3QL3A 3DRCA 1CZ3A 4EIZA 1RD7A 1KMVA 3DL6A 4Q0EA 3NZDA 3EEJA 3RO9A 1PD9A 5HI6A 3SGYA 1U71A 2FZJA 3SRUX 3JWCA 3NZ9X 3I3RA 3FRBX 1DYRA 3FS6A 3QGTA 3GHWA 4OR7A 1DR6A 1DRFA 1DIUA 3L3RA 4HA9A 4X5JA 4I13A 2AZNA 1KMSA 3FL8A 2CD2A 3KFYA 3QYOA 3NXOA 3NTZA 3SRWX 3UM5A 3QG2A 3ZPCA 1MVTA 4XRBA 1KLKA 1DR3A 3FYVX 2CIGA 4LAEX 3EX8A 4ECKA 3F0VX 2HXVA 3SAIA 3FQFA 3FRFX 2FZIA 3IA5A 1RA2A 3LG4A 1HFRA 2W3VA 4LEKX 4DP3A 1MVSA 4H96A 1TDRA 3GHVA 4DPHA 3INVA 3OAFA 4I1NA 4DFRA 1DYJA 1RB2A 3DGAA 4P68A 3HBBA 3QYLA 5FDAA 4EIGA 3K47A 4M2XA 2DHFA 3ROAA 3CSEA 3FRAX 3NRRA 3S3VA 3GI2A 1J3IA 3JWFA 1DLRA 3QLRA 3NXYA 2D0KA 2ANOA 4FGGA 5U26A 1IA1A 2ITHA 2D5NA 1RF7A 4KAKA 4XECX 4H95A 3NU0A 3F0QX 3UM8A 2P4GA 3JVXA 1OHKA 1VJ3A 4LAGX 5HQZA 3JW5A 4X5HA 1RX6A 4XE6X 4PTJA 1DLSA 1E26A 1AOEA 2O7PA 4XT4A 1DR1A 1J3JA 3GYFA 1DDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FQ0 A;  4IXG X;  1DR7 A;  4KLX A;  2W3M A;  4KM0 A;  3SR5 X;  4H98 A;  3I8A X;  5CC9 A;  2B3Z A;  3CD2 A;  3F0S X;  1D1G A;  1RA3 A;  4M7V A;  4X5I A;  2GD9 A;  4KJK A;  3F0U X;  3KGY A;  1DF7 A;  2BLB A;  1PD8 A;  5CCC A;  1AO8 A;  4X5G A;  2HQP A;  3EIG A;  3FRE X;  1U70 A;  1DIS A;  1J3K A;  4FGH A;  4EIL A;  5HUI A;  1BOZ A;  5HVB A;  3SH2 A;  3CLB A;  3F8Y A;  4M6L A;  1DR5 A;  1S3W A;  1PDB A;  4QHV A;  3DAT A;  2W3W A;  3CL9 A;  2OBC A;  3FQO A;  3NXV A;  3IX9 A;  3F8Z A;  1DDS A;  5HT4 A;  4DPD A;  1VDR A;  1RX2 A;  1RX3 A;  1OHJ A;  4KJJ A;  2C2T A;  1JOL A;  3JWM A;  1HFQ A;  1DHI A;  4P3Q A;  1DR2 A;  2L28 A;  3QLZ A;  2QK8 A;  3FY8 X;  5EAJ A;  1DYH A;  2BL9 A;  3DAU A;  4HA7 A;  5DXV A;  4Q0D A;  2W9G A;  4ELF A;  4LAH X;  3TQ9 A;  4KD7 A;  3JSU A;  4KYA A;  2W9S A;  3EEK A;  3Q1H A;  3TD8 A;  1QZF A;  3SA2 A;  4M6J A;  4KFJ A;  3K74 A;  1M78 A;  6DFR A;  4Q6A A;  4KL9 A;  3KJR A;  1RX5 A;  1DRA A;  2H2Q A;  1LUD A;  1JOM A;  3GHC A;  4HOG A;  4Q67 A;  3NXT A;  4G95 A;  4NX7 A;  3SRQ X;  3FRD X;  3QLW A;  3VCO A;  1DG8 A;  5ECC A;  3IA4 A;  3UM6 A;  1CD2 A;  3FQC A;  3EEL A;  4P66 A;  5HVE A;  3OCH A;  1LY3 A;  3N0H A;  4XT7 A;  1BZF A;  5ECX A;  1DHF A;  1DG5 A;  1RC4 A;  3JTW A;  4KNE A;  3FY9 X;  4G8Z X;  3QFX A;  5HT5 A;  4XT5 A;  4OSG A;  2W3B A;  8DFR A;  4TU5 X;  5HQY A;  4XT8 A;  4HOF A;  2FZH A;  3FL9 A;  4QLG A;  3SQY X;  4HOE A;  3QLS A;  1RG7 A;  3DL5 A;  4PSS A;  4ELE A;  3S7A A;  1DG7 A;  4KEB A;  3D84 X;  4QLF A;  5DFR A;  2JYB A;  2W9T A;  1JUV A;  3D80 A;  3DG8 A;  1U72 A;  3F0X X;  3SRR X;  3NXX A;  1YHO A;  3K2H A;  7DFR A;  2C2S A;  4PST A;  4PTH A;  5HF2 X;  3S9U A;  1DYI A;  1RA9 A;  3JW3 A;  1DRH A;  1RH3 A;  1RX1 A;  4KM2 A;  2W3A A;  4IXE D;  3SRS X;  1ZDR A;  1RE7 A;  4KBN A;  3SA1 A;  3F91 A;  4GH8 A;  1IA3 A;  1HFP A;  3M09 A;  3TQA A;  1RB3 A;  2DRC A;  2INQ A;  1S3U A;  4KY8 A;  1SEJ A;  4M6K A;  4ELB A;  4XT6 A;  5HSU A;  4G3M A;  5E8Q A;  4ELG A;  1LY4 A;  3NZC X;  1RA8 A;  5JG0 X;  4RGC A;  1DRB A;  4KJL A;  5U27 A;  3JWK A;  3FQZ A;  3NXR A;  4X5F A;  4IXF X;  3KY8 A;  3NZB X;  4KY4 A;  4QJZ D;  1S3Y A;  4M7U A;  3DFR A;  3TQ8 A;  2XW7 A;  3IRM A;  3IRN A;  4ELH A;  3K45 A;  3QLX A;  3R33 A;  2KGK A;  4PDJ A;  3TQB A;  4EJ1 A;  4QJC A;  4P3R A;  3M08 A;  3F0B X;  5HPB A;  4PSY A;  1AI9 A;  3EEM A;  3NZ6 X;  1RX9 A;  1RX7 A;  3IRO A;  5HSR A;  3RG9 A;  4NX6 A;  1M7A A;  3QL0 A;  1RA1 A;  3FQV A;  5JA3 A;  2W9H A;  3KJS A;  1M79 A;  4CD2 A;  4FHB A;  1DAJ A;  1S3V A;  3ZPG A;  3FYW X;  1IA4 A;  2G6V A;  2HM9 A;  4DDR A;  2ANQ A;  2BLC A;  2ZZA A;  3E0B A;  1RX8 A;  3NZA X;  4H97 A;  1DHJ A;  1RX4 A;  3HJ3 A;  4QI9 A;  1IA2 A;  2OIP A;  4QLE A;  2BLA A;  1DR4 A;  5HF0 X;  1DRE A;  3QLY A;  2LF1 A;  3QL3 A;  3DRC A;  1CZ3 A;  4EIZ A;  1RD7 A;  1KMV A;  3DL6 A;  4Q0E A;  3NZD A;  3EEJ A;  3RO9 A;  1PD9 A;  5HI6 A;  3SGY A;  1U71 A;  2FZJ A;  3SRU X;  3JWC A;  3NZ9 X;  3I3R A;  3FRB X;  1DYR A;  3FS6 A;  3QGT A;  3GHW A;  4OR7 A;  1DR6 A;  1DRF A;  1DIU A;  3L3R A;  4HA9 A;  4X5J A;  4I13 A;  2AZN A;  1KMS A;  3FL8 A;  2CD2 A;  3KFY A;  3QYO A;  3NXO A;  3NTZ A;  3SRW X;  3UM5 A;  3QG2 A;  3ZPC A;  1MVT A;  4XRB A;  1KLK A;  1DR3 A;  3FYV X;  2CIG A;  4LAE X;  3EX8 A;  4ECK A;  3F0V X;  2HXV A;  3SAI A;  3FQF A;  3FRF X;  2FZI A;  3IA5 A;  1RA2 A;  3LG4 A;  1HFR A;  2W3V A;  4LEK X;  4DP3 A;  1MVS A;  4H96 A;  1TDR A;  3GHV A;  4DPH A;  3INV A;  3OAF A;  4I1N A;  4DFR A;  1DYJ A;  1RB2 A;  3DGA A;  4P68 A;  3HBB A;  3QYL A;  5FDA A;  4EIG A;  3K47 A;  4M2X A;  2DHF A;  3ROA A;  3CSE A;  3FRA X;  3NRR A;  3S3V A;  3GI2 A;  1J3I A;  3JWF A;  1DLR A;  3QLR A;  3NXY A;  2D0K A;  2ANO A;  4FGG A;  5U26 A;  1IA1 A;  2ITH A;  2D5N A;  1RF7 A;  4KAK A;  4XEC X;  4H95 A;  3NU0 A;  3F0Q X;  3UM8 A;  2P4G A;  3JVX A;  1OHK A;  1VJ3 A;  4LAG X;  5HQZ A;  3JW5 A;  4X5H A;  1RX6 A;  4XE6 X;  4PTJ A;  1DLS A;  1E26 A;  1AOE A;  2O7P A;  4XT4 A;  1DR1 A;  1J3J A;  3GYF A;  1DDR A; 
#chains in the Genus database with same CATH topology
 3FQ0 A;  4IXG X;  1DR7 A;  4KLX A;  2W3M A;  4KM0 A;  3SR5 X;  4H98 A;  3I8A X;  5CC9 A;  2B3Z A;  3CD2 A;  3F0S X;  1D1G A;  1RA3 A;  4M7V A;  4X5I A;  2GD9 A;  4KJK A;  3F0U X;  3KGY A;  1DF7 A;  2BLB A;  1PD8 A;  5CCC A;  1AO8 A;  4X5G A;  2HQP A;  3EIG A;  3FRE X;  1U70 A;  1DIS A;  1J3K A;  4FGH A;  4EIL A;  5HUI A;  1BOZ A;  5HVB A;  3SH2 A;  3CLB A;  3F8Y A;  4M6L A;  1DR5 A;  1S3W A;  1PDB A;  4QHV A;  3DAT A;  2W3W A;  3CL9 A;  2OBC A;  3FQO A;  3NXV A;  3IX9 A;  3F8Z A;  1DDS A;  5HT4 A;  4DPD A;  1VDR A;  1RX2 A;  1RX3 A;  1OHJ A;  4KJJ A;  2C2T A;  1JOL A;  3JWM A;  1HFQ A;  1DHI A;  4P3Q A;  1DR2 A;  2L28 A;  3QLZ A;  2QK8 A;  3FY8 X;  5EAJ A;  1DYH A;  2BL9 A;  3DAU A;  4HA7 A;  5DXV A;  4Q0D A;  2W9G A;  4ELF A;  4LAH X;  3TQ9 A;  4KD7 A;  3JSU A;  4KYA A;  2W9S A;  3EEK A;  3Q1H A;  3TD8 A;  1QZF A;  3SA2 A;  4M6J A;  4KFJ A;  3K74 A;  1M78 A;  6DFR A;  4Q6A A;  4KL9 A;  3KJR A;  1RX5 A;  1DRA A;  2H2Q A;  1LUD A;  1JOM A;  3GHC A;  4HOG A;  4Q67 A;  3NXT A;  4G95 A;  4NX7 A;  3SRQ X;  3FRD X;  3QLW A;  3VCO A;  1DG8 A;  5ECC A;  3IA4 A;  3UM6 A;  1CD2 A;  3FQC A;  3EEL A;  4P66 A;  5HVE A;  3OCH A;  1LY3 A;  3N0H A;  4XT7 A;  1BZF A;  5ECX A;  1DHF A;  1DG5 A;  1RC4 A;  3JTW A;  4KNE A;  3FY9 X;  4G8Z X;  3QFX A;  5HT5 A;  4XT5 A;  4OSG A;  2W3B A;  8DFR A;  4TU5 X;  5HQY A;  4XT8 A;  4HOF A;  2FZH A;  3FL9 A;  4QLG A;  3SQY X;  4HOE A;  3QLS A;  1RG7 A;  3DL5 A;  4PSS A;  4ELE A;  3S7A A;  1DG7 A;  4KEB A;  3D84 X;  4QLF A;  5DFR A;  2JYB A;  2W9T A;  1JUV A;  3D80 A;  3DG8 A;  1U72 A;  3F0X X;  3SRR X;  3NXX A;  1YHO A;  3K2H A;  7DFR A;  2C2S A;  4PST A;  4PTH A;  5HF2 X;  3S9U A;  1DYI A;  1RA9 A;  3JW3 A;  1DRH A;  1RH3 A;  1RX1 A;  4KM2 A;  2W3A A;  4IXE D;  3SRS X;  1ZDR A;  1RE7 A;  4KBN A;  3SA1 A;  3F91 A;  4GH8 A;  1IA3 A;  1HFP A;  3M09 A;  3TQA A;  1RB3 A;  2DRC A;  2INQ A;  1S3U A;  4KY8 A;  1SEJ A;  4M6K A;  4ELB A;  4XT6 A;  5HSU A;  4G3M A;  5E8Q A;  4ELG A;  1LY4 A;  3NZC X;  1RA8 A;  5JG0 X;  4RGC A;  1DRB A;  4KJL A;  5U27 A;  3JWK A;  3FQZ A;  3NXR A;  4X5F A;  4IXF X;  3KY8 A;  3NZB X;  4KY4 A;  4QJZ D;  1S3Y A;  4M7U A;  3DFR A;  3TQ8 A;  2XW7 A;  3IRM A;  3IRN A;  4ELH A;  3K45 A;  3QLX A;  3R33 A;  2KGK A;  4PDJ A;  3TQB A;  4EJ1 A;  4QJC A;  4P3R A;  3M08 A;  3F0B X;  5HPB A;  4PSY A;  1AI9 A;  3EEM A;  3NZ6 X;  1RX9 A;  1RX7 A;  3IRO A;  5HSR A;  3RG9 A;  4NX6 A;  1M7A A;  3QL0 A;  1RA1 A;  3FQV A;  5JA3 A;  2W9H A;  3KJS A;  1M79 A;  4CD2 A;  4FHB A;  1DAJ A;  1S3V A;  3ZPG A;  3FYW X;  1IA4 A;  2G6V A;  2HM9 A;  4DDR A;  2ANQ A;  2BLC A;  2ZZA A;  3E0B A;  1RX8 A;  3NZA X;  4H97 A;  1DHJ A;  1RX4 A;  3HJ3 A;  4QI9 A;  1IA2 A;  2OIP A;  4QLE A;  2BLA A;  1DR4 A;  5HF0 X;  1DRE A;  3QLY A;  2LF1 A;  3QL3 A;  3DRC A;  1CZ3 A;  4EIZ A;  1RD7 A;  1KMV A;  3DL6 A;  4Q0E A;  3NZD A;  3EEJ A;  3RO9 A;  1PD9 A;  5HI6 A;  3SGY A;  1U71 A;  2FZJ A;  3SRU X;  3JWC A;  3NZ9 X;  3I3R A;  3FRB X;  1DYR A;  3FS6 A;  3QGT A;  3GHW A;  4OR7 A;  1DR6 A;  1DRF A;  1DIU A;  3L3R A;  4HA9 A;  4X5J A;  4I13 A;  2AZN A;  1KMS A;  3FL8 A;  2CD2 A;  3KFY A;  3QYO A;  3NXO A;  3NTZ A;  3SRW X;  3UM5 A;  3QG2 A;  3ZPC A;  1MVT A;  4XRB A;  1KLK A;  1DR3 A;  3FYV X;  2CIG A;  4LAE X;  3EX8 A;  4ECK A;  3F0V X;  2HXV A;  3SAI A;  3FQF A;  3FRF X;  2FZI A;  3IA5 A;  1RA2 A;  3LG4 A;  1HFR A;  2W3V A;  4LEK X;  4DP3 A;  1MVS A;  4H96 A;  1TDR A;  3GHV A;  4DPH A;  3INV A;  3OAF A;  4I1N A;  4DFR A;  1DYJ A;  1RB2 A;  3DGA A;  4P68 A;  3HBB A;  3QYL A;  5FDA A;  4EIG A;  3K47 A;  4M2X A;  2DHF A;  3ROA A;  3CSE A;  3FRA X;  3NRR A;  3S3V A;  3GI2 A;  1J3I A;  3JWF A;  1DLR A;  3QLR A;  3NXY A;  2D0K A;  2ANO A;  4FGG A;  5U26 A;  1IA1 A;  2ITH A;  2D5N A;  1RF7 A;  4KAK A;  4XEC X;  4H95 A;  3NU0 A;  3F0Q X;  3UM8 A;  2P4G A;  3JVX A;  1OHK A;  1VJ3 A;  4LAG X;  5HQZ A;  3JW5 A;  4X5H A;  1RX6 A;  4XE6 X;  4PTJ A;  1DLS A;  1E26 A;  1AOE A;  2O7P A;  4XT4 A;  1DR1 A;  1J3J A;  3GYF A;  1DDR A; 
#chains in the Genus database with same CATH homology
 3FQ0 A;  4IXG X;  1DR7 A;  4KLX A;  2W3M A;  4KM0 A;  3SR5 X;  4H98 A;  3I8A X;  5CC9 A;  2B3Z A;  3CD2 A;  3F0S X;  1D1G A;  1RA3 A;  4M7V A;  4X5I A;  2GD9 A;  4KJK A;  3F0U X;  3KGY A;  1DF7 A;  2BLB A;  1PD8 A;  5CCC A;  1AO8 A;  4X5G A;  2HQP A;  3EIG A;  3FRE X;  1U70 A;  1DIS A;  1J3K A;  4FGH A;  4EIL A;  5HUI A;  1BOZ A;  5HVB A;  3SH2 A;  3CLB A;  3F8Y A;  4M6L A;  1DR5 A;  1S3W A;  1PDB A;  4QHV A;  3DAT A;  2W3W A;  3CL9 A;  2OBC A;  3FQO A;  3NXV A;  3IX9 A;  3F8Z A;  1DDS A;  5HT4 A;  4DPD A;  1VDR A;  1RX2 A;  1RX3 A;  1OHJ A;  4KJJ A;  2C2T A;  1JOL A;  3JWM A;  1HFQ A;  1DHI A;  4P3Q A;  1DR2 A;  2L28 A;  3QLZ A;  2QK8 A;  3FY8 X;  5EAJ A;  1DYH A;  2BL9 A;  3DAU A;  4HA7 A;  5DXV A;  4Q0D A;  2W9G A;  4ELF A;  4LAH X;  3TQ9 A;  4KD7 A;  3JSU A;  4KYA A;  2W9S A;  3EEK A;  3Q1H A;  3TD8 A;  1QZF A;  3SA2 A;  4M6J A;  4KFJ A;  3K74 A;  1M78 A;  6DFR A;  4Q6A A;  4KL9 A;  3KJR A;  1RX5 A;  1DRA A;  2H2Q A;  1LUD A;  1JOM A;  3GHC A;  4HOG A;  4Q67 A;  3NXT A;  4G95 A;  4NX7 A;  3SRQ X;  3FRD X;  3QLW A;  3VCO A;  1DG8 A;  5ECC A;  3IA4 A;  3UM6 A;  1CD2 A;  3FQC A;  3EEL A;  4P66 A;  5HVE A;  3OCH A;  1LY3 A;  3N0H A;  4XT7 A;  1BZF A;  5ECX A;  1DHF A;  1DG5 A;  1RC4 A;  3JTW A;  4KNE A;  3FY9 X;  4G8Z X;  3QFX A;  5HT5 A;  4XT5 A;  4OSG A;  2W3B A;  8DFR A;  4TU5 X;  5HQY A;  4XT8 A;  4HOF A;  2FZH A;  3FL9 A;  4QLG A;  3SQY X;  4HOE A;  3QLS A;  1RG7 A;  3DL5 A;  4PSS A;  4ELE A;  3S7A A;  1DG7 A;  4KEB A;  3D84 X;  4QLF A;  5DFR A;  2JYB A;  2W9T A;  1JUV A;  3D80 A;  3DG8 A;  1U72 A;  3F0X X;  3SRR X;  3NXX A;  1YHO A;  3K2H A;  7DFR A;  2C2S A;  4PST A;  4PTH A;  5HF2 X;  3S9U A;  1DYI A;  1RA9 A;  3JW3 A;  1DRH A;  1RH3 A;  1RX1 A;  4KM2 A;  2W3A A;  4IXE D;  3SRS X;  1ZDR A;  1RE7 A;  4KBN A;  3SA1 A;  3F91 A;  4GH8 A;  1IA3 A;  1HFP A;  3M09 A;  3TQA A;  1RB3 A;  2DRC A;  2INQ A;  1S3U A;  4KY8 A;  1SEJ A;  4M6K A;  4ELB A;  4XT6 A;  5HSU A;  4G3M A;  5E8Q A;  4ELG A;  1LY4 A;  3NZC X;  1RA8 A;  5JG0 X;  4RGC A;  1DRB A;  4KJL A;  5U27 A;  3JWK A;  3FQZ A;  3NXR A;  4X5F A;  4IXF X;  3KY8 A;  3NZB X;  4KY4 A;  4QJZ D;  1S3Y A;  4M7U A;  3DFR A;  3TQ8 A;  2XW7 A;  3IRM A;  3IRN A;  4ELH A;  3K45 A;  3QLX A;  3R33 A;  2KGK A;  4PDJ A;  3TQB A;  4EJ1 A;  4QJC A;  4P3R A;  3M08 A;  3F0B X;  5HPB A;  4PSY A;  1AI9 A;  3EEM A;  3NZ6 X;  1RX9 A;  1RX7 A;  3IRO A;  5HSR A;  3RG9 A;  4NX6 A;  1M7A A;  3QL0 A;  1RA1 A;  3FQV A;  5JA3 A;  2W9H A;  3KJS A;  1M79 A;  4CD2 A;  4FHB A;  1DAJ A;  1S3V A;  3ZPG A;  3FYW X;  1IA4 A;  2G6V A;  2HM9 A;  4DDR A;  2ANQ A;  2BLC A;  2ZZA A;  3E0B A;  1RX8 A;  3NZA X;  4H97 A;  1DHJ A;  1RX4 A;  3HJ3 A;  4QI9 A;  1IA2 A;  2OIP A;  4QLE A;  2BLA A;  1DR4 A;  5HF0 X;  1DRE A;  3QLY A;  2LF1 A;  3QL3 A;  3DRC A;  1CZ3 A;  4EIZ A;  1RD7 A;  1KMV A;  3DL6 A;  4Q0E A;  3NZD A;  3EEJ A;  3RO9 A;  1PD9 A;  5HI6 A;  3SGY A;  1U71 A;  2FZJ A;  3SRU X;  3JWC A;  3NZ9 X;  3I3R A;  3FRB X;  1DYR A;  3FS6 A;  3QGT A;  3GHW A;  4OR7 A;  1DR6 A;  1DRF A;  1DIU A;  3L3R A;  4HA9 A;  4X5J A;  4I13 A;  2AZN A;  1KMS A;  3FL8 A;  2CD2 A;  3KFY A;  3QYO A;  3NXO A;  3NTZ A;  3SRW X;  3UM5 A;  3QG2 A;  3ZPC A;  1MVT A;  4XRB A;  1KLK A;  1DR3 A;  3FYV X;  2CIG A;  4LAE X;  3EX8 A;  4ECK A;  3F0V X;  2HXV A;  3SAI A;  3FQF A;  3FRF X;  2FZI A;  3IA5 A;  1RA2 A;  3LG4 A;  1HFR A;  2W3V A;  4LEK X;  4DP3 A;  1MVS A;  4H96 A;  1TDR A;  3GHV A;  4DPH A;  3INV A;  3OAF A;  4I1N A;  4DFR A;  1DYJ A;  1RB2 A;  3DGA A;  4P68 A;  3HBB A;  3QYL A;  5FDA A;  4EIG A;  3K47 A;  4M2X A;  2DHF A;  3ROA A;  3CSE A;  3FRA X;  3NRR A;  3S3V A;  3GI2 A;  1J3I A;  3JWF A;  1DLR A;  3QLR A;  3NXY A;  2D0K A;  2ANO A;  4FGG A;  5U26 A;  1IA1 A;  2ITH A;  2D5N A;  1RF7 A;  4KAK A;  4XEC X;  4H95 A;  3NU0 A;  3F0Q X;  3UM8 A;  2P4G A;  3JVX A;  1OHK A;  1VJ3 A;  4LAG X;  5HQZ A;  3JW5 A;  4X5H A;  1RX6 A;  4XE6 X;  4PTJ A;  1DLS A;  1E26 A;  1AOE A;  2O7P A;  4XT4 A;  1DR1 A;  1J3J A;  3GYF A;  1DDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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