3QL0A

Crystal structure of n23pp/s148a mutant of e. coli dihydrofolate reductase
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
160
structure length
160
Chain Sequence
MISLIAALAVDRVIGMENAMPWPPLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNAHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 43
structure length 160
sequence length 160
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3ql0A00
1DR3A 3SRUX 4EIZA 1RX5A 3F0UX 3NXTA 3UM6A 2LF1A 4G3MA 7DFRA 1S3WA 1RF7A 1RD7A 1RB3A 3TQAA 4M7UA 1AI9A 1DYRA 3M09A 1DG5A 3F0BX 3NZBX 3VCOA 3K45A 3FQCA 1DYJA 1DHJA 4KEBA 1YHOA 2XW7A 3FY9X 2ANQA 3NZ9X 3RO9A 4KFJA 3FQFA 1KMSA 4H95A 4HOFA 4XECX 3KJSA 4P3QA 4KY4A 3Q1HA 1MVTA 1DR6A 2ANOA 3QG2A 3F0XX 3S7AA 2D5NA 1S3UA 4EJ1A 4X5GA 2W3VA 4QLGA 1KMVA 1LY3A 3L3RA 3QL0A 3TD8A 3SR5X 3DFRA 4HOEA 1DLSA 3KGYA 1AOEA 4XT5A 1ZDRA 4H98A 4HA9A 1RX7A 3SQYX 3FREX 3QYOA 3FQVA 1J3KA 3F0QX 4G8ZX 2CIGA 4IXED 4KAKA 1RC4A 3NTZA 1PDBA 2H2QA 1DRHA 1DYHA 2FZHA 3N0HA 4QJZD 3JW3A 2HM9A 4Q6AA 4ELBA 4PDJA 3QLRA 1RB2A 5HQYA 3CD2A 5U26A 4OSGA 3SAIA 4FGHA 3EEMA 2BLAA 2C2SA 3EX8A 1RH3A 2HXVA 3DL5A 1DG7A 5HT4A 2W9GA 1IA2A 1IA1A 1BZFA 3FY8X 3SH2A 1DR5A 2BL9A 2D0KA 4KL9A 1DISA 4QLFA 1DR2A 3FQ0A 1RE7A 4EIGA 1RA8A 1RX1A 1TDRA 3SRRX 1DG8A 3FYWX 3F0VX 4XRBA 1JOMA 3QL3A 3K74A 4X5JA 3ZPGA 1SEJA 2QK8A 4GH8A 8DFRA 4XT8A 4LEKX 4ELEA 1HFRA 1RX3A 4XT7A 1DREA 4P3RA 3SRSX 4G95A 5EAJA 4M6KA 3NZ6X 4Q0DA 1OHJA 2B3ZA 3JW5A 4PSSA 1J3IA 4KJKA 5HI6A 4M6LA 4X5IA 3EEJA 1RA3A 5DXVA 5HPBA 4KD7A 1PD8A 3NZCX 4PTJA 2ITHA 2HQPA 2W3MA 4NX6A 3F0SX 4PSYA 3DGAA 1MVSA 3NRRA 3D80A 1U72A 3FRFX 4IXFX 2W3AA 1D1GA 1HFPA 4KYAA 3LG4A 4DPDA 4DPHA 3FRBX 3FL9A 3GHCA 3DATA 4QJCA 4FGGA 3QLXA 2ZZAA 3UM5A 4P66A 4DP3A 1RX2A 3K47A 4DDRA 5FDAA 1DRBA 1IA4A 2BLBA 3FQOA 3JWFA 3NXVA 3QGTA 4I13A 3JWCA 2OBCA 3IA5A 1VDRA 1RA1A 1RA9A 3D84X 4LAGX 4LAHX 3NZDA 1HFQA 1RX4A 2W9HA 2JYBA 1U71A 3QLWA 5JA3A 5HVEA 5CCCA 2BLCA 3JWMA 1BOZA 1PD9A 2CD2A 3EELA 4CD2A 4KBNA 3I8AX 6DFRA 3SRQX 3SA2A 3KFYA 1DR7A 3FQZA 3TQBA 1JOLA 4KM2A 3GI2A 3SRWX 1AO8A 3JTWA 4M7VA 5DFRA 1M7AA 3S9UA 3IX9A 3QLZA 4FHBA 3R33A 1VJ3A 4KJLA 4X5HA 3GHVA 2GD9A 4Q67A 5CC9A 1OHKA 3HBBA 4PSTA 1RX9A 3GHWA 1S3VA 5HSRA 3UM8A 4KY8A 1RX8A 1DDRA 1IA3A 1DAJA 3F8ZA 2DRCA 1DR4A 4X5FA 4NX7A 2C2TA 1DHFA 4Q0EA 4M2XA 3EEKA 4OR7A 2G6VA 1DR1A 4LAEX 3QFXA 3NU0A 5ECCA 2AZNA 1LUDA 3SA1A 3GYFA 3JWKA 4TU5X 2W9TA 5HQZA 3QLSA 3FRAX 3INVA 3FYVX 4H96A 1DIUA 5HF0X 1DRFA 4ELHA 1CD2A 4ECKA 2KGKA 3OAFA 3S3VA 3DL6A 4XE6X 3NXYA 3NXRA 4KLXA 3JSUA 3DG8A 3F8YA 3KY8A 4QLEA 2DHFA 1JUVA 5HT5A 4KM0A 3IRMA 4QHVA 5HUIA 3IA4A 3F91A 2INQA 4I1NA 3CSEA 3SGYA 3NXOA 1KLKA 3E0BA 3NZAX 4IXGX 3CLBA 4ELFA 3QLYA 3KJRA 2O7PA 3ZPCA 3EIGA 3OCHA 5HF2X 1DRAA 1RA2A 4PTHA 3JVXA 3CL9A 1M79A 5HVBA 4HOGA 4ELGA 4HA7A 1J3JA 1DYIA 4EILA 3TQ8A 3ROAA 4H97A 4RGCA 3FRDX 4P68A 3NXXA 3HJ3A 3TQ9A 4DFRA 5HSUA 3IROA 1RG7A 1U70A 4XT6A 3FL8A 1QZFA 2L28A 1CZ3A 3DAUA 4KJJA 2FZIA 1M78A 2FZJA 4QI9A 3RG9A 1S3YA 3IRNA 1DLRA 5JG0X 3K2HA 3DRCA 2W3WA 2W9SA 3FS6A 5U27A 1DF7A 2P4GA 5E8QA 1DHIA 3QYLA 3M08A 1E26A 3I3RA 2OIPA 1DDSA 1RX6A 4KNEA 2W3BA 4M6JA 4XT4A 1LY4A 5ECXA
chains in the Genus database with same CATH superfamily
1DR3A 3SRUX 4EIZA 1RX5A 3F0UX 3NXTA 3UM6A 2LF1A 4G3MA 7DFRA 1S3WA 1RF7A 1RD7A 1RB3A 3TQAA 4M7UA 1AI9A 1DYRA 3M09A 1DG5A 3F0BX 3NZBX 3VCOA 3K45A 3FQCA 1DYJA 1DHJA 4KEBA 1YHOA 2XW7A 3FY9X 2ANQA 3NZ9X 3RO9A 4KFJA 3FQFA 1KMSA 4H95A 4HOFA 4XECX 3KJSA 4P3QA 4KY4A 3Q1HA 1MVTA 1DR6A 2ANOA 3QG2A 3F0XX 3S7AA 2D5NA 1S3UA 4EJ1A 4X5GA 2W3VA 4QLGA 1KMVA 1LY3A 3L3RA 3QL0A 3TD8A 3SR5X 3DFRA 4HOEA 1DLSA 3KGYA 1AOEA 4XT5A 1ZDRA 4H98A 4HA9A 1RX7A 3SQYX 3FREX 3QYOA 3FQVA 1J3KA 3F0QX 4G8ZX 2CIGA 4IXED 4KAKA 1RC4A 3NTZA 1PDBA 2H2QA 1DRHA 1DYHA 2FZHA 3N0HA 4QJZD 3JW3A 2HM9A 4Q6AA 4ELBA 4PDJA 3QLRA 1RB2A 5HQYA 3CD2A 5U26A 4OSGA 3SAIA 4FGHA 3EEMA 2BLAA 2C2SA 3EX8A 1RH3A 2HXVA 3DL5A 1DG7A 5HT4A 2W9GA 1IA2A 1IA1A 1BZFA 3FY8X 3SH2A 1DR5A 2BL9A 2D0KA 4KL9A 1DISA 4QLFA 1DR2A 3FQ0A 1RE7A 4EIGA 1RA8A 1RX1A 1TDRA 3SRRX 1DG8A 3FYWX 3F0VX 4XRBA 1JOMA 3QL3A 3K74A 4X5JA 3ZPGA 1SEJA 2QK8A 4GH8A 8DFRA 4XT8A 4LEKX 4ELEA 1HFRA 1RX3A 4XT7A 1DREA 4P3RA 3SRSX 4G95A 5EAJA 4M6KA 3NZ6X 4Q0DA 1OHJA 2B3ZA 3JW5A 4PSSA 1J3IA 4KJKA 5HI6A 4M6LA 4X5IA 3EEJA 1RA3A 5DXVA 5HPBA 4KD7A 1PD8A 3NZCX 4PTJA 2ITHA 2HQPA 2W3MA 4NX6A 3F0SX 4PSYA 3DGAA 1MVSA 3NRRA 3D80A 1U72A 3FRFX 4IXFX 2W3AA 1D1GA 1HFPA 4KYAA 3LG4A 4DPDA 4DPHA 3FRBX 3FL9A 3GHCA 3DATA 4QJCA 4FGGA 3QLXA 2ZZAA 3UM5A 4P66A 4DP3A 1RX2A 3K47A 4DDRA 5FDAA 1DRBA 1IA4A 2BLBA 3FQOA 3JWFA 3NXVA 3QGTA 4I13A 3JWCA 2OBCA 3IA5A 1VDRA 1RA1A 1RA9A 3D84X 4LAGX 4LAHX 3NZDA 1HFQA 1RX4A 2W9HA 2JYBA 1U71A 3QLWA 5JA3A 5HVEA 5CCCA 2BLCA 3JWMA 1BOZA 1PD9A 2CD2A 3EELA 4CD2A 4KBNA 3I8AX 6DFRA 3SRQX 3SA2A 3KFYA 1DR7A 3FQZA 3TQBA 1JOLA 4KM2A 3GI2A 3SRWX 1AO8A 3JTWA 4M7VA 5DFRA 1M7AA 3S9UA 3IX9A 3QLZA 4FHBA 3R33A 1VJ3A 4KJLA 4X5HA 3GHVA 2GD9A 4Q67A 5CC9A 1OHKA 3HBBA 4PSTA 1RX9A 3GHWA 1S3VA 5HSRA 3UM8A 4KY8A 1RX8A 1DDRA 1IA3A 1DAJA 3F8ZA 2DRCA 1DR4A 4X5FA 4NX7A 2C2TA 1DHFA 4Q0EA 4M2XA 3EEKA 4OR7A 2G6VA 1DR1A 4LAEX 3QFXA 3NU0A 5ECCA 2AZNA 1LUDA 3SA1A 3GYFA 3JWKA 4TU5X 2W9TA 5HQZA 3QLSA 3FRAX 3INVA 3FYVX 4H96A 1DIUA 5HF0X 1DRFA 4ELHA 1CD2A 4ECKA 2KGKA 3OAFA 3S3VA 3DL6A 4XE6X 3NXYA 3NXRA 4KLXA 3JSUA 3DG8A 3F8YA 3KY8A 4QLEA 2DHFA 1JUVA 5HT5A 4KM0A 3IRMA 4QHVA 5HUIA 3IA4A 3F91A 2INQA 4I1NA 3CSEA 3SGYA 3NXOA 1KLKA 3E0BA 3NZAX 4IXGX 3CLBA 4ELFA 3QLYA 3KJRA 2O7PA 3ZPCA 3EIGA 3OCHA 5HF2X 1DRAA 1RA2A 4PTHA 3JVXA 3CL9A 1M79A 5HVBA 4HOGA 4ELGA 4HA7A 1J3JA 1DYIA 4EILA 3TQ8A 3ROAA 4H97A 4RGCA 3FRDX 4P68A 3NXXA 3HJ3A 3TQ9A 4DFRA 5HSUA 3IROA 1RG7A 1U70A 4XT6A 3FL8A 1QZFA 2L28A 1CZ3A 3DAUA 4KJJA 2FZIA 1M78A 2FZJA 4QI9A 3RG9A 1S3YA 3IRNA 1DLRA 5JG0X 3K2HA 3DRCA 2W3WA 2W9SA 3FS6A 5U27A 1DF7A 2P4GA 5E8QA 1DHIA 3QYLA 3M08A 1E26A 3I3RA 2OIPA 1DDSA 1RX6A 4KNEA 2W3BA 4M6JA 4XT4A 1LY4A 5ECXA
chains in the Genus database with same CATH topology
1DR3A 3SRUX 4EIZA 1RX5A 3F0UX 3NXTA 3UM6A 2LF1A 4G3MA 7DFRA 1S3WA 1RF7A 1RD7A 1RB3A 3TQAA 4M7UA 1AI9A 1DYRA 3M09A 1DG5A 3F0BX 3NZBX 3VCOA 3K45A 3FQCA 1DYJA 1DHJA 4KEBA 1YHOA 2XW7A 3FY9X 2ANQA 3NZ9X 3RO9A 4KFJA 3FQFA 1KMSA 4H95A 4HOFA 4XECX 3KJSA 4P3QA 4KY4A 3Q1HA 1MVTA 1DR6A 2ANOA 3QG2A 3F0XX 3S7AA 2D5NA 1S3UA 4EJ1A 4X5GA 2W3VA 4QLGA 1KMVA 1LY3A 3L3RA 3QL0A 3TD8A 3SR5X 3DFRA 4HOEA 1DLSA 3KGYA 1AOEA 4XT5A 1ZDRA 4H98A 4HA9A 1RX7A 3SQYX 3FREX 3QYOA 3FQVA 1J3KA 3F0QX 4G8ZX 2CIGA 4IXED 4KAKA 1RC4A 3NTZA 1PDBA 2H2QA 1DRHA 1DYHA 2FZHA 3N0HA 4QJZD 3JW3A 2HM9A 4Q6AA 4ELBA 4PDJA 3QLRA 1RB2A 5HQYA 3CD2A 5U26A 4OSGA 3SAIA 4FGHA 3EEMA 2BLAA 2C2SA 3EX8A 1RH3A 2HXVA 3DL5A 1DG7A 5HT4A 2W9GA 1IA2A 1IA1A 1BZFA 3FY8X 3SH2A 1DR5A 2BL9A 2D0KA 4KL9A 1DISA 4QLFA 1DR2A 3FQ0A 1RE7A 4EIGA 1RA8A 1RX1A 1TDRA 3SRRX 1DG8A 3FYWX 3F0VX 4XRBA 1JOMA 3QL3A 3K74A 4X5JA 3ZPGA 1SEJA 2QK8A 4GH8A 8DFRA 4XT8A 4LEKX 4ELEA 1HFRA 1RX3A 4XT7A 1DREA 4P3RA 3SRSX 4G95A 5EAJA 4M6KA 3NZ6X 4Q0DA 1OHJA 2B3ZA 3JW5A 4PSSA 1J3IA 4KJKA 5HI6A 4M6LA 4X5IA 3EEJA 1RA3A 5DXVA 5HPBA 4KD7A 1PD8A 3NZCX 4PTJA 2ITHA 2HQPA 2W3MA 4NX6A 3F0SX 4PSYA 3DGAA 1MVSA 3NRRA 3D80A 1U72A 3FRFX 4IXFX 2W3AA 1D1GA 1HFPA 4KYAA 3LG4A 4DPDA 4DPHA 3FRBX 3FL9A 3GHCA 3DATA 4QJCA 4FGGA 3QLXA 2ZZAA 3UM5A 4P66A 4DP3A 1RX2A 3K47A 4DDRA 5FDAA 1DRBA 1IA4A 2BLBA 3FQOA 3JWFA 3NXVA 3QGTA 4I13A 3JWCA 2OBCA 3IA5A 1VDRA 1RA1A 1RA9A 3D84X 4LAGX 4LAHX 3NZDA 1HFQA 1RX4A 2W9HA 2JYBA 1U71A 3QLWA 5JA3A 5HVEA 5CCCA 2BLCA 3JWMA 1BOZA 1PD9A 2CD2A 3EELA 4CD2A 4KBNA 3I8AX 6DFRA 3SRQX 3SA2A 3KFYA 1DR7A 3FQZA 3TQBA 1JOLA 4KM2A 3GI2A 3SRWX 1AO8A 3JTWA 4M7VA 5DFRA 1M7AA 3S9UA 3IX9A 3QLZA 4FHBA 3R33A 1VJ3A 4KJLA 4X5HA 3GHVA 2GD9A 4Q67A 5CC9A 1OHKA 3HBBA 4PSTA 1RX9A 3GHWA 1S3VA 5HSRA 3UM8A 4KY8A 1RX8A 1DDRA 1IA3A 1DAJA 3F8ZA 2DRCA 1DR4A 4X5FA 4NX7A 2C2TA 1DHFA 4Q0EA 4M2XA 3EEKA 4OR7A 2G6VA 1DR1A 4LAEX 3QFXA 3NU0A 5ECCA 2AZNA 1LUDA 3SA1A 3GYFA 3JWKA 4TU5X 2W9TA 5HQZA 3QLSA 3FRAX 3INVA 3FYVX 4H96A 1DIUA 5HF0X 1DRFA 4ELHA 1CD2A 4ECKA 2KGKA 3OAFA 3S3VA 3DL6A 4XE6X 3NXYA 3NXRA 4KLXA 3JSUA 3DG8A 3F8YA 3KY8A 4QLEA 2DHFA 1JUVA 5HT5A 4KM0A 3IRMA 4QHVA 5HUIA 3IA4A 3F91A 2INQA 4I1NA 3CSEA 3SGYA 3NXOA 1KLKA 3E0BA 3NZAX 4IXGX 3CLBA 4ELFA 3QLYA 3KJRA 2O7PA 3ZPCA 3EIGA 3OCHA 5HF2X 1DRAA 1RA2A 4PTHA 3JVXA 3CL9A 1M79A 5HVBA 4HOGA 4ELGA 4HA7A 1J3JA 1DYIA 4EILA 3TQ8A 3ROAA 4H97A 4RGCA 3FRDX 4P68A 3NXXA 3HJ3A 3TQ9A 4DFRA 5HSUA 3IROA 1RG7A 1U70A 4XT6A 3FL8A 1QZFA 2L28A 1CZ3A 3DAUA 4KJJA 2FZIA 1M78A 2FZJA 4QI9A 3RG9A 1S3YA 3IRNA 1DLRA 5JG0X 3K2HA 3DRCA 2W3WA 2W9SA 3FS6A 5U27A 1DF7A 2P4GA 5E8QA 1DHIA 3QYLA 3M08A 1E26A 3I3RA 2OIPA 1DDSA 1RX6A 4KNEA 2W3BA 4M6JA 4XT4A 1LY4A 5ECXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DR3 A;  3SRU X;  4EIZ A;  1RX5 A;  3F0U X;  3NXT A;  3UM6 A;  2LF1 A;  4G3M A;  7DFR A;  1S3W A;  1RF7 A;  1RD7 A;  1RB3 A;  3TQA A;  4M7U A;  1AI9 A;  1DYR A;  3M09 A;  1DG5 A;  3F0B X;  3NZB X;  3VCO A;  3K45 A;  3FQC A;  1DYJ A;  1DHJ A;  4KEB A;  1YHO A;  2XW7 A;  3FY9 X;  2ANQ A;  3NZ9 X;  3RO9 A;  4KFJ A;  3FQF A;  1KMS A;  4H95 A;  4HOF A;  4XEC X;  3KJS A;  4P3Q A;  4KY4 A;  3Q1H A;  1MVT A;  1DR6 A;  2ANO A;  3QG2 A;  3F0X X;  3S7A A;  2D5N A;  1S3U A;  4EJ1 A;  4X5G A;  2W3V A;  4QLG A;  1KMV A;  1LY3 A;  3L3R A;  3QL0 A;  3TD8 A;  3SR5 X;  3DFR A;  4HOE A;  1DLS A;  3KGY A;  1AOE A;  4XT5 A;  1ZDR A;  4H98 A;  4HA9 A;  1RX7 A;  3SQY X;  3FRE X;  3QYO A;  3FQV A;  1J3K A;  3F0Q X;  4G8Z X;  2CIG A;  4IXE D;  4KAK A;  1RC4 A;  3NTZ A;  1PDB A;  2H2Q A;  1DRH A;  1DYH A;  2FZH A;  3N0H A;  4QJZ D;  3JW3 A;  2HM9 A;  4Q6A A;  4ELB A;  4PDJ A;  3QLR A;  1RB2 A;  5HQY A;  3CD2 A;  5U26 A;  4OSG A;  3SAI A;  4FGH A;  3EEM A;  2BLA A;  2C2S A;  3EX8 A;  1RH3 A;  2HXV A;  3DL5 A;  1DG7 A;  5HT4 A;  2W9G A;  1IA2 A;  1IA1 A;  1BZF A;  3FY8 X;  3SH2 A;  1DR5 A;  2BL9 A;  2D0K A;  4KL9 A;  1DIS A;  4QLF A;  1DR2 A;  3FQ0 A;  1RE7 A;  4EIG A;  1RA8 A;  1RX1 A;  1TDR A;  3SRR X;  1DG8 A;  3FYW X;  3F0V X;  4XRB A;  1JOM A;  3QL3 A;  3K74 A;  4X5J A;  3ZPG A;  1SEJ A;  2QK8 A;  4GH8 A;  8DFR A;  4XT8 A;  4LEK X;  4ELE A;  1HFR A;  1RX3 A;  4XT7 A;  1DRE A;  4P3R A;  3SRS X;  4G95 A;  5EAJ A;  4M6K A;  3NZ6 X;  4Q0D A;  1OHJ A;  2B3Z A;  3JW5 A;  4PSS A;  1J3I A;  4KJK A;  5HI6 A;  4M6L A;  4X5I A;  3EEJ A;  1RA3 A;  5DXV A;  5HPB A;  4KD7 A;  1PD8 A;  3NZC X;  4PTJ A;  2ITH A;  2HQP A;  2W3M A;  4NX6 A;  3F0S X;  4PSY A;  3DGA A;  1MVS A;  3NRR A;  3D80 A;  1U72 A;  3FRF X;  4IXF X;  2W3A A;  1D1G A;  1HFP A;  4KYA A;  3LG4 A;  4DPD A;  4DPH A;  3FRB X;  3FL9 A;  3GHC A;  3DAT A;  4QJC A;  4FGG A;  3QLX A;  2ZZA A;  3UM5 A;  4P66 A;  4DP3 A;  1RX2 A;  3K47 A;  4DDR A;  5FDA A;  1DRB A;  1IA4 A;  2BLB A;  3FQO A;  3JWF A;  3NXV A;  3QGT A;  4I13 A;  3JWC A;  2OBC A;  3IA5 A;  1VDR A;  1RA1 A;  1RA9 A;  3D84 X;  4LAG X;  4LAH X;  3NZD A;  1HFQ A;  1RX4 A;  2W9H A;  2JYB A;  1U71 A;  3QLW A;  5JA3 A;  5HVE A;  5CCC A;  2BLC A;  3JWM A;  1BOZ A;  1PD9 A;  2CD2 A;  3EEL A;  4CD2 A;  4KBN A;  3I8A X;  6DFR A;  3SRQ X;  3SA2 A;  3KFY A;  1DR7 A;  3FQZ A;  3TQB A;  1JOL A;  4KM2 A;  3GI2 A;  3SRW X;  1AO8 A;  3JTW A;  4M7V A;  5DFR A;  1M7A A;  3S9U A;  3IX9 A;  3QLZ A;  4FHB A;  3R33 A;  1VJ3 A;  4KJL A;  4X5H A;  3GHV A;  2GD9 A;  4Q67 A;  5CC9 A;  1OHK A;  3HBB A;  4PST A;  1RX9 A;  3GHW A;  1S3V A;  5HSR A;  3UM8 A;  4KY8 A;  1RX8 A;  1DDR A;  1IA3 A;  1DAJ A;  3F8Z A;  2DRC A;  1DR4 A;  4X5F A;  4NX7 A;  2C2T A;  1DHF A;  4Q0E A;  4M2X A;  3EEK A;  4OR7 A;  2G6V A;  1DR1 A;  4LAE X;  3QFX A;  3NU0 A;  5ECC A;  2AZN A;  1LUD A;  3SA1 A;  3GYF A;  3JWK A;  4TU5 X;  2W9T A;  5HQZ A;  3QLS A;  3FRA X;  3INV A;  3FYV X;  4H96 A;  1DIU A;  5HF0 X;  1DRF A;  4ELH A;  1CD2 A;  4ECK A;  2KGK A;  3OAF A;  3S3V A;  3DL6 A;  4XE6 X;  3NXY A;  3NXR A;  4KLX A;  3JSU A;  3DG8 A;  3F8Y A;  3KY8 A;  4QLE A;  2DHF A;  1JUV A;  5HT5 A;  4KM0 A;  3IRM A;  4QHV A;  5HUI A;  3IA4 A;  3F91 A;  2INQ A;  4I1N A;  3CSE A;  3SGY A;  3NXO A;  1KLK A;  3E0B A;  3NZA X;  4IXG X;  3CLB A;  4ELF A;  3QLY A;  3KJR A;  2O7P A;  3ZPC A;  3EIG A;  3OCH A;  5HF2 X;  1DRA A;  1RA2 A;  4PTH A;  3JVX A;  3CL9 A;  1M79 A;  5HVB A;  4HOG A;  4ELG A;  4HA7 A;  1J3J A;  1DYI A;  4EIL A;  3TQ8 A;  3ROA A;  4H97 A;  4RGC A;  3FRD X;  4P68 A;  3NXX A;  3HJ3 A;  3TQ9 A;  4DFR A;  5HSU A;  3IRO A;  1RG7 A;  1U70 A;  4XT6 A;  3FL8 A;  1QZF A;  2L28 A;  1CZ3 A;  3DAU A;  4KJJ A;  2FZI A;  1M78 A;  2FZJ A;  4QI9 A;  3RG9 A;  1S3Y A;  3IRN A;  1DLR A;  5JG0 X;  3K2H A;  3DRC A;  2W3W A;  2W9S A;  3FS6 A;  5U27 A;  1DF7 A;  2P4G A;  5E8Q A;  1DHI A;  3QYL A;  3M08 A;  1E26 A;  3I3R A;  2OIP A;  1DDS A;  1RX6 A;  4KNE A;  2W3B A;  4M6J A;  4XT4 A;  1LY4 A;  5ECX A; 
#chains in the Genus database with same CATH topology
 1DR3 A;  3SRU X;  4EIZ A;  1RX5 A;  3F0U X;  3NXT A;  3UM6 A;  2LF1 A;  4G3M A;  7DFR A;  1S3W A;  1RF7 A;  1RD7 A;  1RB3 A;  3TQA A;  4M7U A;  1AI9 A;  1DYR A;  3M09 A;  1DG5 A;  3F0B X;  3NZB X;  3VCO A;  3K45 A;  3FQC A;  1DYJ A;  1DHJ A;  4KEB A;  1YHO A;  2XW7 A;  3FY9 X;  2ANQ A;  3NZ9 X;  3RO9 A;  4KFJ A;  3FQF A;  1KMS A;  4H95 A;  4HOF A;  4XEC X;  3KJS A;  4P3Q A;  4KY4 A;  3Q1H A;  1MVT A;  1DR6 A;  2ANO A;  3QG2 A;  3F0X X;  3S7A A;  2D5N A;  1S3U A;  4EJ1 A;  4X5G A;  2W3V A;  4QLG A;  1KMV A;  1LY3 A;  3L3R A;  3QL0 A;  3TD8 A;  3SR5 X;  3DFR A;  4HOE A;  1DLS A;  3KGY A;  1AOE A;  4XT5 A;  1ZDR A;  4H98 A;  4HA9 A;  1RX7 A;  3SQY X;  3FRE X;  3QYO A;  3FQV A;  1J3K A;  3F0Q X;  4G8Z X;  2CIG A;  4IXE D;  4KAK A;  1RC4 A;  3NTZ A;  1PDB A;  2H2Q A;  1DRH A;  1DYH A;  2FZH A;  3N0H A;  4QJZ D;  3JW3 A;  2HM9 A;  4Q6A A;  4ELB A;  4PDJ A;  3QLR A;  1RB2 A;  5HQY A;  3CD2 A;  5U26 A;  4OSG A;  3SAI A;  4FGH A;  3EEM A;  2BLA A;  2C2S A;  3EX8 A;  1RH3 A;  2HXV A;  3DL5 A;  1DG7 A;  5HT4 A;  2W9G A;  1IA2 A;  1IA1 A;  1BZF A;  3FY8 X;  3SH2 A;  1DR5 A;  2BL9 A;  2D0K A;  4KL9 A;  1DIS A;  4QLF A;  1DR2 A;  3FQ0 A;  1RE7 A;  4EIG A;  1RA8 A;  1RX1 A;  1TDR A;  3SRR X;  1DG8 A;  3FYW X;  3F0V X;  4XRB A;  1JOM A;  3QL3 A;  3K74 A;  4X5J A;  3ZPG A;  1SEJ A;  2QK8 A;  4GH8 A;  8DFR A;  4XT8 A;  4LEK X;  4ELE A;  1HFR A;  1RX3 A;  4XT7 A;  1DRE A;  4P3R A;  3SRS X;  4G95 A;  5EAJ A;  4M6K A;  3NZ6 X;  4Q0D A;  1OHJ A;  2B3Z A;  3JW5 A;  4PSS A;  1J3I A;  4KJK A;  5HI6 A;  4M6L A;  4X5I A;  3EEJ A;  1RA3 A;  5DXV A;  5HPB A;  4KD7 A;  1PD8 A;  3NZC X;  4PTJ A;  2ITH A;  2HQP A;  2W3M A;  4NX6 A;  3F0S X;  4PSY A;  3DGA A;  1MVS A;  3NRR A;  3D80 A;  1U72 A;  3FRF X;  4IXF X;  2W3A A;  1D1G A;  1HFP A;  4KYA A;  3LG4 A;  4DPD A;  4DPH A;  3FRB X;  3FL9 A;  3GHC A;  3DAT A;  4QJC A;  4FGG A;  3QLX A;  2ZZA A;  3UM5 A;  4P66 A;  4DP3 A;  1RX2 A;  3K47 A;  4DDR A;  5FDA A;  1DRB A;  1IA4 A;  2BLB A;  3FQO A;  3JWF A;  3NXV A;  3QGT A;  4I13 A;  3JWC A;  2OBC A;  3IA5 A;  1VDR A;  1RA1 A;  1RA9 A;  3D84 X;  4LAG X;  4LAH X;  3NZD A;  1HFQ A;  1RX4 A;  2W9H A;  2JYB A;  1U71 A;  3QLW A;  5JA3 A;  5HVE A;  5CCC A;  2BLC A;  3JWM A;  1BOZ A;  1PD9 A;  2CD2 A;  3EEL A;  4CD2 A;  4KBN A;  3I8A X;  6DFR A;  3SRQ X;  3SA2 A;  3KFY A;  1DR7 A;  3FQZ A;  3TQB A;  1JOL A;  4KM2 A;  3GI2 A;  3SRW X;  1AO8 A;  3JTW A;  4M7V A;  5DFR A;  1M7A A;  3S9U A;  3IX9 A;  3QLZ A;  4FHB A;  3R33 A;  1VJ3 A;  4KJL A;  4X5H A;  3GHV A;  2GD9 A;  4Q67 A;  5CC9 A;  1OHK A;  3HBB A;  4PST A;  1RX9 A;  3GHW A;  1S3V A;  5HSR A;  3UM8 A;  4KY8 A;  1RX8 A;  1DDR A;  1IA3 A;  1DAJ A;  3F8Z A;  2DRC A;  1DR4 A;  4X5F A;  4NX7 A;  2C2T A;  1DHF A;  4Q0E A;  4M2X A;  3EEK A;  4OR7 A;  2G6V A;  1DR1 A;  4LAE X;  3QFX A;  3NU0 A;  5ECC A;  2AZN A;  1LUD A;  3SA1 A;  3GYF A;  3JWK A;  4TU5 X;  2W9T A;  5HQZ A;  3QLS A;  3FRA X;  3INV A;  3FYV X;  4H96 A;  1DIU A;  5HF0 X;  1DRF A;  4ELH A;  1CD2 A;  4ECK A;  2KGK A;  3OAF A;  3S3V A;  3DL6 A;  4XE6 X;  3NXY A;  3NXR A;  4KLX A;  3JSU A;  3DG8 A;  3F8Y A;  3KY8 A;  4QLE A;  2DHF A;  1JUV A;  5HT5 A;  4KM0 A;  3IRM A;  4QHV A;  5HUI A;  3IA4 A;  3F91 A;  2INQ A;  4I1N A;  3CSE A;  3SGY A;  3NXO A;  1KLK A;  3E0B A;  3NZA X;  4IXG X;  3CLB A;  4ELF A;  3QLY A;  3KJR A;  2O7P A;  3ZPC A;  3EIG A;  3OCH A;  5HF2 X;  1DRA A;  1RA2 A;  4PTH A;  3JVX A;  3CL9 A;  1M79 A;  5HVB A;  4HOG A;  4ELG A;  4HA7 A;  1J3J A;  1DYI A;  4EIL A;  3TQ8 A;  3ROA A;  4H97 A;  4RGC A;  3FRD X;  4P68 A;  3NXX A;  3HJ3 A;  3TQ9 A;  4DFR A;  5HSU A;  3IRO A;  1RG7 A;  1U70 A;  4XT6 A;  3FL8 A;  1QZF A;  2L28 A;  1CZ3 A;  3DAU A;  4KJJ A;  2FZI A;  1M78 A;  2FZJ A;  4QI9 A;  3RG9 A;  1S3Y A;  3IRN A;  1DLR A;  5JG0 X;  3K2H A;  3DRC A;  2W3W A;  2W9S A;  3FS6 A;  5U27 A;  1DF7 A;  2P4G A;  5E8Q A;  1DHI A;  3QYL A;  3M08 A;  1E26 A;  3I3R A;  2OIP A;  1DDS A;  1RX6 A;  4KNE A;  2W3B A;  4M6J A;  4XT4 A;  1LY4 A;  5ECX A; 
#chains in the Genus database with same CATH homology
 1DR3 A;  3SRU X;  4EIZ A;  1RX5 A;  3F0U X;  3NXT A;  3UM6 A;  2LF1 A;  4G3M A;  7DFR A;  1S3W A;  1RF7 A;  1RD7 A;  1RB3 A;  3TQA A;  4M7U A;  1AI9 A;  1DYR A;  3M09 A;  1DG5 A;  3F0B X;  3NZB X;  3VCO A;  3K45 A;  3FQC A;  1DYJ A;  1DHJ A;  4KEB A;  1YHO A;  2XW7 A;  3FY9 X;  2ANQ A;  3NZ9 X;  3RO9 A;  4KFJ A;  3FQF A;  1KMS A;  4H95 A;  4HOF A;  4XEC X;  3KJS A;  4P3Q A;  4KY4 A;  3Q1H A;  1MVT A;  1DR6 A;  2ANO A;  3QG2 A;  3F0X X;  3S7A A;  2D5N A;  1S3U A;  4EJ1 A;  4X5G A;  2W3V A;  4QLG A;  1KMV A;  1LY3 A;  3L3R A;  3QL0 A;  3TD8 A;  3SR5 X;  3DFR A;  4HOE A;  1DLS A;  3KGY A;  1AOE A;  4XT5 A;  1ZDR A;  4H98 A;  4HA9 A;  1RX7 A;  3SQY X;  3FRE X;  3QYO A;  3FQV A;  1J3K A;  3F0Q X;  4G8Z X;  2CIG A;  4IXE D;  4KAK A;  1RC4 A;  3NTZ A;  1PDB A;  2H2Q A;  1DRH A;  1DYH A;  2FZH A;  3N0H A;  4QJZ D;  3JW3 A;  2HM9 A;  4Q6A A;  4ELB A;  4PDJ A;  3QLR A;  1RB2 A;  5HQY A;  3CD2 A;  5U26 A;  4OSG A;  3SAI A;  4FGH A;  3EEM A;  2BLA A;  2C2S A;  3EX8 A;  1RH3 A;  2HXV A;  3DL5 A;  1DG7 A;  5HT4 A;  2W9G A;  1IA2 A;  1IA1 A;  1BZF A;  3FY8 X;  3SH2 A;  1DR5 A;  2BL9 A;  2D0K A;  4KL9 A;  1DIS A;  4QLF A;  1DR2 A;  3FQ0 A;  1RE7 A;  4EIG A;  1RA8 A;  1RX1 A;  1TDR A;  3SRR X;  1DG8 A;  3FYW X;  3F0V X;  4XRB A;  1JOM A;  3QL3 A;  3K74 A;  4X5J A;  3ZPG A;  1SEJ A;  2QK8 A;  4GH8 A;  8DFR A;  4XT8 A;  4LEK X;  4ELE A;  1HFR A;  1RX3 A;  4XT7 A;  1DRE A;  4P3R A;  3SRS X;  4G95 A;  5EAJ A;  4M6K A;  3NZ6 X;  4Q0D A;  1OHJ A;  2B3Z A;  3JW5 A;  4PSS A;  1J3I A;  4KJK A;  5HI6 A;  4M6L A;  4X5I A;  3EEJ A;  1RA3 A;  5DXV A;  5HPB A;  4KD7 A;  1PD8 A;  3NZC X;  4PTJ A;  2ITH A;  2HQP A;  2W3M A;  4NX6 A;  3F0S X;  4PSY A;  3DGA A;  1MVS A;  3NRR A;  3D80 A;  1U72 A;  3FRF X;  4IXF X;  2W3A A;  1D1G A;  1HFP A;  4KYA A;  3LG4 A;  4DPD A;  4DPH A;  3FRB X;  3FL9 A;  3GHC A;  3DAT A;  4QJC A;  4FGG A;  3QLX A;  2ZZA A;  3UM5 A;  4P66 A;  4DP3 A;  1RX2 A;  3K47 A;  4DDR A;  5FDA A;  1DRB A;  1IA4 A;  2BLB A;  3FQO A;  3JWF A;  3NXV A;  3QGT A;  4I13 A;  3JWC A;  2OBC A;  3IA5 A;  1VDR A;  1RA1 A;  1RA9 A;  3D84 X;  4LAG X;  4LAH X;  3NZD A;  1HFQ A;  1RX4 A;  2W9H A;  2JYB A;  1U71 A;  3QLW A;  5JA3 A;  5HVE A;  5CCC A;  2BLC A;  3JWM A;  1BOZ A;  1PD9 A;  2CD2 A;  3EEL A;  4CD2 A;  4KBN A;  3I8A X;  6DFR A;  3SRQ X;  3SA2 A;  3KFY A;  1DR7 A;  3FQZ A;  3TQB A;  1JOL A;  4KM2 A;  3GI2 A;  3SRW X;  1AO8 A;  3JTW A;  4M7V A;  5DFR A;  1M7A A;  3S9U A;  3IX9 A;  3QLZ A;  4FHB A;  3R33 A;  1VJ3 A;  4KJL A;  4X5H A;  3GHV A;  2GD9 A;  4Q67 A;  5CC9 A;  1OHK A;  3HBB A;  4PST A;  1RX9 A;  3GHW A;  1S3V A;  5HSR A;  3UM8 A;  4KY8 A;  1RX8 A;  1DDR A;  1IA3 A;  1DAJ A;  3F8Z A;  2DRC A;  1DR4 A;  4X5F A;  4NX7 A;  2C2T A;  1DHF A;  4Q0E A;  4M2X A;  3EEK A;  4OR7 A;  2G6V A;  1DR1 A;  4LAE X;  3QFX A;  3NU0 A;  5ECC A;  2AZN A;  1LUD A;  3SA1 A;  3GYF A;  3JWK A;  4TU5 X;  2W9T A;  5HQZ A;  3QLS A;  3FRA X;  3INV A;  3FYV X;  4H96 A;  1DIU A;  5HF0 X;  1DRF A;  4ELH A;  1CD2 A;  4ECK A;  2KGK A;  3OAF A;  3S3V A;  3DL6 A;  4XE6 X;  3NXY A;  3NXR A;  4KLX A;  3JSU A;  3DG8 A;  3F8Y A;  3KY8 A;  4QLE A;  2DHF A;  1JUV A;  5HT5 A;  4KM0 A;  3IRM A;  4QHV A;  5HUI A;  3IA4 A;  3F91 A;  2INQ A;  4I1N A;  3CSE A;  3SGY A;  3NXO A;  1KLK A;  3E0B A;  3NZA X;  4IXG X;  3CLB A;  4ELF A;  3QLY A;  3KJR A;  2O7P A;  3ZPC A;  3EIG A;  3OCH A;  5HF2 X;  1DRA A;  1RA2 A;  4PTH A;  3JVX A;  3CL9 A;  1M79 A;  5HVB A;  4HOG A;  4ELG A;  4HA7 A;  1J3J A;  1DYI A;  4EIL A;  3TQ8 A;  3ROA A;  4H97 A;  4RGC A;  3FRD X;  4P68 A;  3NXX A;  3HJ3 A;  3TQ9 A;  4DFR A;  5HSU A;  3IRO A;  1RG7 A;  1U70 A;  4XT6 A;  3FL8 A;  1QZF A;  2L28 A;  1CZ3 A;  3DAU A;  4KJJ A;  2FZI A;  1M78 A;  2FZJ A;  4QI9 A;  3RG9 A;  1S3Y A;  3IRN A;  1DLR A;  5JG0 X;  3K2H A;  3DRC A;  2W3W A;  2W9S A;  3FS6 A;  5U27 A;  1DF7 A;  2P4G A;  5E8Q A;  1DHI A;  3QYL A;  3M08 A;  1E26 A;  3I3R A;  2OIP A;  1DDS A;  1RX6 A;  4KNE A;  2W3B A;  4M6J A;  4XT4 A;  1LY4 A;  5ECX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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