3RG9A

Trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with wr99210
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
218
structure length
218
Chain Sequence
RPPLRPFSVVVASDEKGGIGDGGTIPWEIPEDMQYFRRVTTNLRGKNVKPSPSKRNAVVMGRKTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGIPDPIKRAEAANDVVAVNGGLEDALRMLVSKEHTSSIETVFCIGGGTIYKQALCAPCVNVLQAIHRTVVRPASNSCSVFFDIPAAGTKTPEGLELVRESITDERVSTGAGGKKYQFEKLVPRN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Trypanosomal dihydrofolate reductase reveals natural antifolate resistance
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Trypanosoma brucei rhodesiense
molecule keywords Bifunctional dihydrofolate reductase-thymidylate synthase
total genus 58
structure length 218
sequence length 218
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-04-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3rg9A00
4ELFA 1RA9A 1DG7A 3D84X 3FL8A 3CD2A 4LAEX 2LF1A 2W3WA 2O7PA 4IXGX 3OCHA 2D0KA 3JVXA 3EX8A 3ZPGA 5HSUA 4ELBA 3E0BA 4XT5A 3NXOA 1DHFA 2HM9A 4M7VA 3TQ8A 1RX3A 2BLAA 3FRFX 3Q1HA 2W9TA 3TQ9A 5FDAA 1JOMA 3JWFA 5E8QA 4Q0DA 1RA8A 3JW3A 3CL9A 3QLRA 3EEJA 3L3RA 1OHKA 4PDJA 3NZ6X 5DFRA 1DLRA 3QYLA 4KY4A 3KGYA 3EELA 4NX6A 3FYWX 4DPDA 3FL9A 3QLSA 3K45A 3NXYA 3LG4A 4KFJA 4XECX 4I1NA 1YHOA 1IA2A 1S3UA 2HQPA 3DL6A 3JW5A 3SAIA 4XT4A 3FQVA 3DATA 4HA9A 1DR1A 2ANOA 3KY8A 1PD8A 3FQOA 5ECCA 3QL0A 4NX7A 1DDRA 4KNEA 4CD2A 4KLXA 3TD8A 1RA2A 4X5FA 2C2TA 2H2QA 4DDRA 3SRWX 1DREA 3KFYA 2G6VA 2B3ZA 3SR5X 1RG7A 1DRHA 1RX7A 1DR6A 1DR5A 3IRNA 3EIGA 3TQBA 3KJSA 1BZFA 3CLBA 1DR3A 1M79A 3F0SX 3QFXA 1S3YA 3UM8A 3NZBX 3CSEA 2W3VA 4DFRA 2AZNA 4LAGX 4DPHA 3DAUA 1VDRA 2OBCA 4FGHA 1E26A 2FZIA 4QLGA 3F0UX 4PSTA 3EEMA 1RF7A 2INQA 3OAFA 4EILA 1AI9A 4LEKX 1IA3A 3SGYA 4QJZD 1AO8A 2QK8A 3F8ZA 1DRAA 3M08A 1KLKA 1HFQA 6DFRA 5HI6A 3I8AX 3DFRA 3KJRA 1U71A 2CIGA 5JA3A 2XW7A 1DR4A 4FGGA 5DXVA 3RO9A 3S9UA 3NXXA 1DR7A 3SA1A 2W9HA 4QLEA 4Q67A 5JG0X 4HOGA 5HUIA 4QI9A 5HVBA 2ZZAA 2BLBA 5HT5A 1JOLA 1RX1A 1DIUA 5HF2X 5CCCA 1RA3A 4KY8A 4TU5X 4OR7A 4XRBA 5HF0X 4XE6X 4G3MA 1DRFA 1DHIA 1MVTA 2FZHA 2W3MA 2BLCA 2HXVA 1AOEA 1RD7A 3NXVA 4GH8A 1DLSA 3K74A 4M6JA 1DRBA 4X5HA 3SA2A 4Q6AA 4KM0A 3F0VX 4X5JA 1RE7A 1RA1A 4P3QA 3FRDX 1MVSA 1DYIA 3FQCA 1PD9A 1IA4A 4G95A 4H96A 5HVEA 2W9SA 1RB2A 1CZ3A 4KBNA 1RX4A 4ELGA 1DDSA 1VJ3A 4XT6A 3DRCA 3IROA 3JWCA 5HT4A 3SRSX 1KMVA 1DYJA 4EIZA 1CD2A 4RGCA 3I3RA 3QLWA 1S3VA 3JSUA 3F0BX 3IA5A 2P4GA 3JWKA 1DYRA 3SQYX 2BL9A 2OIPA 3GI2A 3QYOA 1RX9A 5ECXA 1DG5A 1RC4A 1S3WA 5HQZA 3QG2A 1RH3A 3N0HA 3FREX 3DL5A 5HPBA 1J3JA 1DF7A 3GHWA 1DAJA 1RX8A 4M7UA 3F91A 3FRBX 1RB3A 4ECKA 5HSRA 3FQFA 3FYVX 4X5IA 4P66A 4G8ZX 3SRUX 3VCOA 1TDRA 4HOFA 4QHVA 1M7AA 2ANQA 1ZDRA 3FQZA 4ELEA 4P3RA 4M2XA 2DHFA 1BOZA 1D1GA 3NZ9X 3QL3A 1HFPA 1OHJA 3FY8X 3NZAX 3UM6A 4M6KA 3IRMA 3M09A 1DYHA 2KGKA 3F8YA 4PSSA 4KJJA 4PTHA 1M78A 3DGAA 4IXFX 4EIGA 3K47A 1RX2A 3HJ3A 3R33A 3ZPCA 3SRRX 3IX9A 3F0QX 4OSGA 1U70A 5U26A 4KJKA 3GHVA 3RG9A 4H97A 4Q0EA 3ROAA 2DRCA 4PTJA 4XT8A 1LY3A 3IA4A 3NTZA 3QLZA 1IA1A 1J3IA 1QZFA 4P68A 2C2SA 3K2HA 1DISA 3NRRA 1RX5A 3JWMA 1LY4A 2JYBA 1SEJA 3GHCA 3SH2A 2ITHA 5HQYA 4KM2A 4FHBA 1DR2A 3QLXA 4QLFA 2CD2A 3EEKA 4EJ1A 3UM5A 3F0XX 4HA7A 4I13A 3NXRA 3S3VA 2W3AA 3JTWA 3NZDA 4M6LA 1KMSA 1U72A 4KAKA 3D80A 1DHJA 2W3BA 3NU0A 1DG8A 3FRAX 3NZCX 4KJLA 3S7AA 3QLYA 2W9GA 8DFRA 3FS6A 4KD7A 1JUVA 4H98A 4KEBA 3DG8A 7DFRA 4QJCA 4LAHX 3FY9X 2L28A 3INVA 1HFRA 3SRQX 4H95A 2FZJA 5CC9A 1J3KA 3FQ0A 4DP3A 3QGTA 4XT7A 3TQAA 5U27A 1RX6A 2GD9A 4X5GA 5EAJA 1PDBA 4KYAA 4HOEA 2D5NA 4PSYA 3HBBA 3GYFA 3NXTA 1LUDA 4ELHA 4KL9A 4IXED
chains in the Genus database with same CATH superfamily
4ELFA 1RA9A 1DG7A 3D84X 3FL8A 3CD2A 4LAEX 2LF1A 2W3WA 2O7PA 4IXGX 3OCHA 2D0KA 3JVXA 3EX8A 3ZPGA 5HSUA 4ELBA 3E0BA 4XT5A 3NXOA 1DHFA 2HM9A 4M7VA 3TQ8A 1RX3A 2BLAA 3FRFX 3Q1HA 2W9TA 3TQ9A 5FDAA 1JOMA 3JWFA 5E8QA 4Q0DA 1RA8A 3JW3A 3CL9A 3QLRA 3EEJA 3L3RA 1OHKA 4PDJA 3NZ6X 5DFRA 1DLRA 3QYLA 4KY4A 3KGYA 3EELA 4NX6A 3FYWX 4DPDA 3FL9A 3QLSA 3K45A 3NXYA 3LG4A 4KFJA 4XECX 4I1NA 1YHOA 1IA2A 1S3UA 2HQPA 3DL6A 3JW5A 3SAIA 4XT4A 3FQVA 3DATA 4HA9A 1DR1A 2ANOA 3KY8A 1PD8A 3FQOA 5ECCA 3QL0A 4NX7A 1DDRA 4KNEA 4CD2A 4KLXA 3TD8A 1RA2A 4X5FA 2C2TA 2H2QA 4DDRA 3SRWX 1DREA 3KFYA 2G6VA 2B3ZA 3SR5X 1RG7A 1DRHA 1RX7A 1DR6A 1DR5A 3IRNA 3EIGA 3TQBA 3KJSA 1BZFA 3CLBA 1DR3A 1M79A 3F0SX 3QFXA 1S3YA 3UM8A 3NZBX 3CSEA 2W3VA 4DFRA 2AZNA 4LAGX 4DPHA 3DAUA 1VDRA 2OBCA 4FGHA 1E26A 2FZIA 4QLGA 3F0UX 4PSTA 3EEMA 1RF7A 2INQA 3OAFA 4EILA 1AI9A 4LEKX 1IA3A 3SGYA 4QJZD 1AO8A 2QK8A 3F8ZA 1DRAA 3M08A 1KLKA 1HFQA 6DFRA 5HI6A 3I8AX 3DFRA 3KJRA 1U71A 2CIGA 5JA3A 2XW7A 1DR4A 4FGGA 5DXVA 3RO9A 3S9UA 3NXXA 1DR7A 3SA1A 2W9HA 4QLEA 4Q67A 5JG0X 4HOGA 5HUIA 4QI9A 5HVBA 2ZZAA 2BLBA 5HT5A 1JOLA 1RX1A 1DIUA 5HF2X 5CCCA 1RA3A 4KY8A 4TU5X 4OR7A 4XRBA 5HF0X 4XE6X 4G3MA 1DRFA 1DHIA 1MVTA 2FZHA 2W3MA 2BLCA 2HXVA 1AOEA 1RD7A 3NXVA 4GH8A 1DLSA 3K74A 4M6JA 1DRBA 4X5HA 3SA2A 4Q6AA 4KM0A 3F0VX 4X5JA 1RE7A 1RA1A 4P3QA 3FRDX 1MVSA 1DYIA 3FQCA 1PD9A 1IA4A 4G95A 4H96A 5HVEA 2W9SA 1RB2A 1CZ3A 4KBNA 1RX4A 4ELGA 1DDSA 1VJ3A 4XT6A 3DRCA 3IROA 3JWCA 5HT4A 3SRSX 1KMVA 1DYJA 4EIZA 1CD2A 4RGCA 3I3RA 3QLWA 1S3VA 3JSUA 3F0BX 3IA5A 2P4GA 3JWKA 1DYRA 3SQYX 2BL9A 2OIPA 3GI2A 3QYOA 1RX9A 5ECXA 1DG5A 1RC4A 1S3WA 5HQZA 3QG2A 1RH3A 3N0HA 3FREX 3DL5A 5HPBA 1J3JA 1DF7A 3GHWA 1DAJA 1RX8A 4M7UA 3F91A 3FRBX 1RB3A 4ECKA 5HSRA 3FQFA 3FYVX 4X5IA 4P66A 4G8ZX 3SRUX 3VCOA 1TDRA 4HOFA 4QHVA 1M7AA 2ANQA 1ZDRA 3FQZA 4ELEA 4P3RA 4M2XA 2DHFA 1BOZA 1D1GA 3NZ9X 3QL3A 1HFPA 1OHJA 3FY8X 3NZAX 3UM6A 4M6KA 3IRMA 3M09A 1DYHA 2KGKA 3F8YA 4PSSA 4KJJA 4PTHA 1M78A 3DGAA 4IXFX 4EIGA 3K47A 1RX2A 3HJ3A 3R33A 3ZPCA 3SRRX 3IX9A 3F0QX 4OSGA 1U70A 5U26A 4KJKA 3GHVA 3RG9A 4H97A 4Q0EA 3ROAA 2DRCA 4PTJA 4XT8A 1LY3A 3IA4A 3NTZA 3QLZA 1IA1A 1J3IA 1QZFA 4P68A 2C2SA 3K2HA 1DISA 3NRRA 1RX5A 3JWMA 1LY4A 2JYBA 1SEJA 3GHCA 3SH2A 2ITHA 5HQYA 4KM2A 4FHBA 1DR2A 3QLXA 4QLFA 2CD2A 3EEKA 4EJ1A 3UM5A 3F0XX 4HA7A 4I13A 3NXRA 3S3VA 2W3AA 3JTWA 3NZDA 4M6LA 1KMSA 1U72A 4KAKA 3D80A 1DHJA 2W3BA 3NU0A 1DG8A 3FRAX 3NZCX 4KJLA 3S7AA 3QLYA 2W9GA 8DFRA 3FS6A 4KD7A 1JUVA 4H98A 4KEBA 3DG8A 7DFRA 4QJCA 4LAHX 3FY9X 2L28A 3INVA 1HFRA 3SRQX 4H95A 2FZJA 5CC9A 1J3KA 3FQ0A 4DP3A 3QGTA 4XT7A 3TQAA 5U27A 1RX6A 2GD9A 4X5GA 5EAJA 1PDBA 4KYAA 4HOEA 2D5NA 4PSYA 3HBBA 3GYFA 3NXTA 1LUDA 4ELHA 4KL9A 4IXED
chains in the Genus database with same CATH topology
4ELFA 1RA9A 1DG7A 3D84X 3FL8A 3CD2A 4LAEX 2LF1A 2W3WA 2O7PA 4IXGX 3OCHA 2D0KA 3JVXA 3EX8A 3ZPGA 5HSUA 4ELBA 3E0BA 4XT5A 3NXOA 1DHFA 2HM9A 4M7VA 3TQ8A 1RX3A 2BLAA 3FRFX 3Q1HA 2W9TA 3TQ9A 5FDAA 1JOMA 3JWFA 5E8QA 4Q0DA 1RA8A 3JW3A 3CL9A 3QLRA 3EEJA 3L3RA 1OHKA 4PDJA 3NZ6X 5DFRA 1DLRA 3QYLA 4KY4A 3KGYA 3EELA 4NX6A 3FYWX 4DPDA 3FL9A 3QLSA 3K45A 3NXYA 3LG4A 4KFJA 4XECX 4I1NA 1YHOA 1IA2A 1S3UA 2HQPA 3DL6A 3JW5A 3SAIA 4XT4A 3FQVA 3DATA 4HA9A 1DR1A 2ANOA 3KY8A 1PD8A 3FQOA 5ECCA 3QL0A 4NX7A 1DDRA 4KNEA 4CD2A 4KLXA 3TD8A 1RA2A 4X5FA 2C2TA 2H2QA 4DDRA 3SRWX 1DREA 3KFYA 2G6VA 2B3ZA 3SR5X 1RG7A 1DRHA 1RX7A 1DR6A 1DR5A 3IRNA 3EIGA 3TQBA 3KJSA 1BZFA 3CLBA 1DR3A 1M79A 3F0SX 3QFXA 1S3YA 3UM8A 3NZBX 3CSEA 2W3VA 4DFRA 2AZNA 4LAGX 4DPHA 3DAUA 1VDRA 2OBCA 4FGHA 1E26A 2FZIA 4QLGA 3F0UX 4PSTA 3EEMA 1RF7A 2INQA 3OAFA 4EILA 1AI9A 4LEKX 1IA3A 3SGYA 4QJZD 1AO8A 2QK8A 3F8ZA 1DRAA 3M08A 1KLKA 1HFQA 6DFRA 5HI6A 3I8AX 3DFRA 3KJRA 1U71A 2CIGA 5JA3A 2XW7A 1DR4A 4FGGA 5DXVA 3RO9A 3S9UA 3NXXA 1DR7A 3SA1A 2W9HA 4QLEA 4Q67A 5JG0X 4HOGA 5HUIA 4QI9A 5HVBA 2ZZAA 2BLBA 5HT5A 1JOLA 1RX1A 1DIUA 5HF2X 5CCCA 1RA3A 4KY8A 4TU5X 4OR7A 4XRBA 5HF0X 4XE6X 4G3MA 1DRFA 1DHIA 1MVTA 2FZHA 2W3MA 2BLCA 2HXVA 1AOEA 1RD7A 3NXVA 4GH8A 1DLSA 3K74A 4M6JA 1DRBA 4X5HA 3SA2A 4Q6AA 4KM0A 3F0VX 4X5JA 1RE7A 1RA1A 4P3QA 3FRDX 1MVSA 1DYIA 3FQCA 1PD9A 1IA4A 4G95A 4H96A 5HVEA 2W9SA 1RB2A 1CZ3A 4KBNA 1RX4A 4ELGA 1DDSA 1VJ3A 4XT6A 3DRCA 3IROA 3JWCA 5HT4A 3SRSX 1KMVA 1DYJA 4EIZA 1CD2A 4RGCA 3I3RA 3QLWA 1S3VA 3JSUA 3F0BX 3IA5A 2P4GA 3JWKA 1DYRA 3SQYX 2BL9A 2OIPA 3GI2A 3QYOA 1RX9A 5ECXA 1DG5A 1RC4A 1S3WA 5HQZA 3QG2A 1RH3A 3N0HA 3FREX 3DL5A 5HPBA 1J3JA 1DF7A 3GHWA 1DAJA 1RX8A 4M7UA 3F91A 3FRBX 1RB3A 4ECKA 5HSRA 3FQFA 3FYVX 4X5IA 4P66A 4G8ZX 3SRUX 3VCOA 1TDRA 4HOFA 4QHVA 1M7AA 2ANQA 1ZDRA 3FQZA 4ELEA 4P3RA 4M2XA 2DHFA 1BOZA 1D1GA 3NZ9X 3QL3A 1HFPA 1OHJA 3FY8X 3NZAX 3UM6A 4M6KA 3IRMA 3M09A 1DYHA 2KGKA 3F8YA 4PSSA 4KJJA 4PTHA 1M78A 3DGAA 4IXFX 4EIGA 3K47A 1RX2A 3HJ3A 3R33A 3ZPCA 3SRRX 3IX9A 3F0QX 4OSGA 1U70A 5U26A 4KJKA 3GHVA 3RG9A 4H97A 4Q0EA 3ROAA 2DRCA 4PTJA 4XT8A 1LY3A 3IA4A 3NTZA 3QLZA 1IA1A 1J3IA 1QZFA 4P68A 2C2SA 3K2HA 1DISA 3NRRA 1RX5A 3JWMA 1LY4A 2JYBA 1SEJA 3GHCA 3SH2A 2ITHA 5HQYA 4KM2A 4FHBA 1DR2A 3QLXA 4QLFA 2CD2A 3EEKA 4EJ1A 3UM5A 3F0XX 4HA7A 4I13A 3NXRA 3S3VA 2W3AA 3JTWA 3NZDA 4M6LA 1KMSA 1U72A 4KAKA 3D80A 1DHJA 2W3BA 3NU0A 1DG8A 3FRAX 3NZCX 4KJLA 3S7AA 3QLYA 2W9GA 8DFRA 3FS6A 4KD7A 1JUVA 4H98A 4KEBA 3DG8A 7DFRA 4QJCA 4LAHX 3FY9X 2L28A 3INVA 1HFRA 3SRQX 4H95A 2FZJA 5CC9A 1J3KA 3FQ0A 4DP3A 3QGTA 4XT7A 3TQAA 5U27A 1RX6A 2GD9A 4X5GA 5EAJA 1PDBA 4KYAA 4HOEA 2D5NA 4PSYA 3HBBA 3GYFA 3NXTA 1LUDA 4ELHA 4KL9A 4IXED
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ELF A;  1RA9 A;  1DG7 A;  3D84 X;  3FL8 A;  3CD2 A;  4LAE X;  2LF1 A;  2W3W A;  2O7P A;  4IXG X;  3OCH A;  2D0K A;  3JVX A;  3EX8 A;  3ZPG A;  5HSU A;  4ELB A;  3E0B A;  4XT5 A;  3NXO A;  1DHF A;  2HM9 A;  4M7V A;  3TQ8 A;  1RX3 A;  2BLA A;  3FRF X;  3Q1H A;  2W9T A;  3TQ9 A;  5FDA A;  1JOM A;  3JWF A;  5E8Q A;  4Q0D A;  1RA8 A;  3JW3 A;  3CL9 A;  3QLR A;  3EEJ A;  3L3R A;  1OHK A;  4PDJ A;  3NZ6 X;  5DFR A;  1DLR A;  3QYL A;  4KY4 A;  3KGY A;  3EEL A;  4NX6 A;  3FYW X;  4DPD A;  3FL9 A;  3QLS A;  3K45 A;  3NXY A;  3LG4 A;  4KFJ A;  4XEC X;  4I1N A;  1YHO A;  1IA2 A;  1S3U A;  2HQP A;  3DL6 A;  3JW5 A;  3SAI A;  4XT4 A;  3FQV A;  3DAT A;  4HA9 A;  1DR1 A;  2ANO A;  3KY8 A;  1PD8 A;  3FQO A;  5ECC A;  3QL0 A;  4NX7 A;  1DDR A;  4KNE A;  4CD2 A;  4KLX A;  3TD8 A;  1RA2 A;  4X5F A;  2C2T A;  2H2Q A;  4DDR A;  3SRW X;  1DRE A;  3KFY A;  2G6V A;  2B3Z A;  3SR5 X;  1RG7 A;  1DRH A;  1RX7 A;  1DR6 A;  1DR5 A;  3IRN A;  3EIG A;  3TQB A;  3KJS A;  1BZF A;  3CLB A;  1DR3 A;  1M79 A;  3F0S X;  3QFX A;  1S3Y A;  3UM8 A;  3NZB X;  3CSE A;  2W3V A;  4DFR A;  2AZN A;  4LAG X;  4DPH A;  3DAU A;  1VDR A;  2OBC A;  4FGH A;  1E26 A;  2FZI A;  4QLG A;  3F0U X;  4PST A;  3EEM A;  1RF7 A;  2INQ A;  3OAF A;  4EIL A;  1AI9 A;  4LEK X;  1IA3 A;  3SGY A;  4QJZ D;  1AO8 A;  2QK8 A;  3F8Z A;  1DRA A;  3M08 A;  1KLK A;  1HFQ A;  6DFR A;  5HI6 A;  3I8A X;  3DFR A;  3KJR A;  1U71 A;  2CIG A;  5JA3 A;  2XW7 A;  1DR4 A;  4FGG A;  5DXV A;  3RO9 A;  3S9U A;  3NXX A;  1DR7 A;  3SA1 A;  2W9H A;  4QLE A;  4Q67 A;  5JG0 X;  4HOG A;  5HUI A;  4QI9 A;  5HVB A;  2ZZA A;  2BLB A;  5HT5 A;  1JOL A;  1RX1 A;  1DIU A;  5HF2 X;  5CCC A;  1RA3 A;  4KY8 A;  4TU5 X;  4OR7 A;  4XRB A;  5HF0 X;  4XE6 X;  4G3M A;  1DRF A;  1DHI A;  1MVT A;  2FZH A;  2W3M A;  2BLC A;  2HXV A;  1AOE A;  1RD7 A;  3NXV A;  4GH8 A;  1DLS A;  3K74 A;  4M6J A;  1DRB A;  4X5H A;  3SA2 A;  4Q6A A;  4KM0 A;  3F0V X;  4X5J A;  1RE7 A;  1RA1 A;  4P3Q A;  3FRD X;  1MVS A;  1DYI A;  3FQC A;  1PD9 A;  1IA4 A;  4G95 A;  4H96 A;  5HVE A;  2W9S A;  1RB2 A;  1CZ3 A;  4KBN A;  1RX4 A;  4ELG A;  1DDS A;  1VJ3 A;  4XT6 A;  3DRC A;  3IRO A;  3JWC A;  5HT4 A;  3SRS X;  1KMV A;  1DYJ A;  4EIZ A;  1CD2 A;  4RGC A;  3I3R A;  3QLW A;  1S3V A;  3JSU A;  3F0B X;  3IA5 A;  2P4G A;  3JWK A;  1DYR A;  3SQY X;  2BL9 A;  2OIP A;  3GI2 A;  3QYO A;  1RX9 A;  5ECX A;  1DG5 A;  1RC4 A;  1S3W A;  5HQZ A;  3QG2 A;  1RH3 A;  3N0H A;  3FRE X;  3DL5 A;  5HPB A;  1J3J A;  1DF7 A;  3GHW A;  1DAJ A;  1RX8 A;  4M7U A;  3F91 A;  3FRB X;  1RB3 A;  4ECK A;  5HSR A;  3FQF A;  3FYV X;  4X5I A;  4P66 A;  4G8Z X;  3SRU X;  3VCO A;  1TDR A;  4HOF A;  4QHV A;  1M7A A;  2ANQ A;  1ZDR A;  3FQZ A;  4ELE A;  4P3R A;  4M2X A;  2DHF A;  1BOZ A;  1D1G A;  3NZ9 X;  3QL3 A;  1HFP A;  1OHJ A;  3FY8 X;  3NZA X;  3UM6 A;  4M6K A;  3IRM A;  3M09 A;  1DYH A;  2KGK A;  3F8Y A;  4PSS A;  4KJJ A;  4PTH A;  1M78 A;  3DGA A;  4IXF X;  4EIG A;  3K47 A;  1RX2 A;  3HJ3 A;  3R33 A;  3ZPC A;  3SRR X;  3IX9 A;  3F0Q X;  4OSG A;  1U70 A;  5U26 A;  4KJK A;  3GHV A;  3RG9 A;  4H97 A;  4Q0E A;  3ROA A;  2DRC A;  4PTJ A;  4XT8 A;  1LY3 A;  3IA4 A;  3NTZ A;  3QLZ A;  1IA1 A;  1J3I A;  1QZF A;  4P68 A;  2C2S A;  3K2H A;  1DIS A;  3NRR A;  1RX5 A;  3JWM A;  1LY4 A;  2JYB A;  1SEJ A;  3GHC A;  3SH2 A;  2ITH A;  5HQY A;  4KM2 A;  4FHB A;  1DR2 A;  3QLX A;  4QLF A;  2CD2 A;  3EEK A;  4EJ1 A;  3UM5 A;  3F0X X;  4HA7 A;  4I13 A;  3NXR A;  3S3V A;  2W3A A;  3JTW A;  3NZD A;  4M6L A;  1KMS A;  1U72 A;  4KAK A;  3D80 A;  1DHJ A;  2W3B A;  3NU0 A;  1DG8 A;  3FRA X;  3NZC X;  4KJL A;  3S7A A;  3QLY A;  2W9G A;  8DFR A;  3FS6 A;  4KD7 A;  1JUV A;  4H98 A;  4KEB A;  3DG8 A;  7DFR A;  4QJC A;  4LAH X;  3FY9 X;  2L28 A;  3INV A;  1HFR A;  3SRQ X;  4H95 A;  2FZJ A;  5CC9 A;  1J3K A;  3FQ0 A;  4DP3 A;  3QGT A;  4XT7 A;  3TQA A;  5U27 A;  1RX6 A;  2GD9 A;  4X5G A;  5EAJ A;  1PDB A;  4KYA A;  4HOE A;  2D5N A;  4PSY A;  3HBB A;  3GYF A;  3NXT A;  1LUD A;  4ELH A;  4KL9 A;  4IXE D; 
#chains in the Genus database with same CATH topology
 4ELF A;  1RA9 A;  1DG7 A;  3D84 X;  3FL8 A;  3CD2 A;  4LAE X;  2LF1 A;  2W3W A;  2O7P A;  4IXG X;  3OCH A;  2D0K A;  3JVX A;  3EX8 A;  3ZPG A;  5HSU A;  4ELB A;  3E0B A;  4XT5 A;  3NXO A;  1DHF A;  2HM9 A;  4M7V A;  3TQ8 A;  1RX3 A;  2BLA A;  3FRF X;  3Q1H A;  2W9T A;  3TQ9 A;  5FDA A;  1JOM A;  3JWF A;  5E8Q A;  4Q0D A;  1RA8 A;  3JW3 A;  3CL9 A;  3QLR A;  3EEJ A;  3L3R A;  1OHK A;  4PDJ A;  3NZ6 X;  5DFR A;  1DLR A;  3QYL A;  4KY4 A;  3KGY A;  3EEL A;  4NX6 A;  3FYW X;  4DPD A;  3FL9 A;  3QLS A;  3K45 A;  3NXY A;  3LG4 A;  4KFJ A;  4XEC X;  4I1N A;  1YHO A;  1IA2 A;  1S3U A;  2HQP A;  3DL6 A;  3JW5 A;  3SAI A;  4XT4 A;  3FQV A;  3DAT A;  4HA9 A;  1DR1 A;  2ANO A;  3KY8 A;  1PD8 A;  3FQO A;  5ECC A;  3QL0 A;  4NX7 A;  1DDR A;  4KNE A;  4CD2 A;  4KLX A;  3TD8 A;  1RA2 A;  4X5F A;  2C2T A;  2H2Q A;  4DDR A;  3SRW X;  1DRE A;  3KFY A;  2G6V A;  2B3Z A;  3SR5 X;  1RG7 A;  1DRH A;  1RX7 A;  1DR6 A;  1DR5 A;  3IRN A;  3EIG A;  3TQB A;  3KJS A;  1BZF A;  3CLB A;  1DR3 A;  1M79 A;  3F0S X;  3QFX A;  1S3Y A;  3UM8 A;  3NZB X;  3CSE A;  2W3V A;  4DFR A;  2AZN A;  4LAG X;  4DPH A;  3DAU A;  1VDR A;  2OBC A;  4FGH A;  1E26 A;  2FZI A;  4QLG A;  3F0U X;  4PST A;  3EEM A;  1RF7 A;  2INQ A;  3OAF A;  4EIL A;  1AI9 A;  4LEK X;  1IA3 A;  3SGY A;  4QJZ D;  1AO8 A;  2QK8 A;  3F8Z A;  1DRA A;  3M08 A;  1KLK A;  1HFQ A;  6DFR A;  5HI6 A;  3I8A X;  3DFR A;  3KJR A;  1U71 A;  2CIG A;  5JA3 A;  2XW7 A;  1DR4 A;  4FGG A;  5DXV A;  3RO9 A;  3S9U A;  3NXX A;  1DR7 A;  3SA1 A;  2W9H A;  4QLE A;  4Q67 A;  5JG0 X;  4HOG A;  5HUI A;  4QI9 A;  5HVB A;  2ZZA A;  2BLB A;  5HT5 A;  1JOL A;  1RX1 A;  1DIU A;  5HF2 X;  5CCC A;  1RA3 A;  4KY8 A;  4TU5 X;  4OR7 A;  4XRB A;  5HF0 X;  4XE6 X;  4G3M A;  1DRF A;  1DHI A;  1MVT A;  2FZH A;  2W3M A;  2BLC A;  2HXV A;  1AOE A;  1RD7 A;  3NXV A;  4GH8 A;  1DLS A;  3K74 A;  4M6J A;  1DRB A;  4X5H A;  3SA2 A;  4Q6A A;  4KM0 A;  3F0V X;  4X5J A;  1RE7 A;  1RA1 A;  4P3Q A;  3FRD X;  1MVS A;  1DYI A;  3FQC A;  1PD9 A;  1IA4 A;  4G95 A;  4H96 A;  5HVE A;  2W9S A;  1RB2 A;  1CZ3 A;  4KBN A;  1RX4 A;  4ELG A;  1DDS A;  1VJ3 A;  4XT6 A;  3DRC A;  3IRO A;  3JWC A;  5HT4 A;  3SRS X;  1KMV A;  1DYJ A;  4EIZ A;  1CD2 A;  4RGC A;  3I3R A;  3QLW A;  1S3V A;  3JSU A;  3F0B X;  3IA5 A;  2P4G A;  3JWK A;  1DYR A;  3SQY X;  2BL9 A;  2OIP A;  3GI2 A;  3QYO A;  1RX9 A;  5ECX A;  1DG5 A;  1RC4 A;  1S3W A;  5HQZ A;  3QG2 A;  1RH3 A;  3N0H A;  3FRE X;  3DL5 A;  5HPB A;  1J3J A;  1DF7 A;  3GHW A;  1DAJ A;  1RX8 A;  4M7U A;  3F91 A;  3FRB X;  1RB3 A;  4ECK A;  5HSR A;  3FQF A;  3FYV X;  4X5I A;  4P66 A;  4G8Z X;  3SRU X;  3VCO A;  1TDR A;  4HOF A;  4QHV A;  1M7A A;  2ANQ A;  1ZDR A;  3FQZ A;  4ELE A;  4P3R A;  4M2X A;  2DHF A;  1BOZ A;  1D1G A;  3NZ9 X;  3QL3 A;  1HFP A;  1OHJ A;  3FY8 X;  3NZA X;  3UM6 A;  4M6K A;  3IRM A;  3M09 A;  1DYH A;  2KGK A;  3F8Y A;  4PSS A;  4KJJ A;  4PTH A;  1M78 A;  3DGA A;  4IXF X;  4EIG A;  3K47 A;  1RX2 A;  3HJ3 A;  3R33 A;  3ZPC A;  3SRR X;  3IX9 A;  3F0Q X;  4OSG A;  1U70 A;  5U26 A;  4KJK A;  3GHV A;  3RG9 A;  4H97 A;  4Q0E A;  3ROA A;  2DRC A;  4PTJ A;  4XT8 A;  1LY3 A;  3IA4 A;  3NTZ A;  3QLZ A;  1IA1 A;  1J3I A;  1QZF A;  4P68 A;  2C2S A;  3K2H A;  1DIS A;  3NRR A;  1RX5 A;  3JWM A;  1LY4 A;  2JYB A;  1SEJ A;  3GHC A;  3SH2 A;  2ITH A;  5HQY A;  4KM2 A;  4FHB A;  1DR2 A;  3QLX A;  4QLF A;  2CD2 A;  3EEK A;  4EJ1 A;  3UM5 A;  3F0X X;  4HA7 A;  4I13 A;  3NXR A;  3S3V A;  2W3A A;  3JTW A;  3NZD A;  4M6L A;  1KMS A;  1U72 A;  4KAK A;  3D80 A;  1DHJ A;  2W3B A;  3NU0 A;  1DG8 A;  3FRA X;  3NZC X;  4KJL A;  3S7A A;  3QLY A;  2W9G A;  8DFR A;  3FS6 A;  4KD7 A;  1JUV A;  4H98 A;  4KEB A;  3DG8 A;  7DFR A;  4QJC A;  4LAH X;  3FY9 X;  2L28 A;  3INV A;  1HFR A;  3SRQ X;  4H95 A;  2FZJ A;  5CC9 A;  1J3K A;  3FQ0 A;  4DP3 A;  3QGT A;  4XT7 A;  3TQA A;  5U27 A;  1RX6 A;  2GD9 A;  4X5G A;  5EAJ A;  1PDB A;  4KYA A;  4HOE A;  2D5N A;  4PSY A;  3HBB A;  3GYF A;  3NXT A;  1LUD A;  4ELH A;  4KL9 A;  4IXE D; 
#chains in the Genus database with same CATH homology
 4ELF A;  1RA9 A;  1DG7 A;  3D84 X;  3FL8 A;  3CD2 A;  4LAE X;  2LF1 A;  2W3W A;  2O7P A;  4IXG X;  3OCH A;  2D0K A;  3JVX A;  3EX8 A;  3ZPG A;  5HSU A;  4ELB A;  3E0B A;  4XT5 A;  3NXO A;  1DHF A;  2HM9 A;  4M7V A;  3TQ8 A;  1RX3 A;  2BLA A;  3FRF X;  3Q1H A;  2W9T A;  3TQ9 A;  5FDA A;  1JOM A;  3JWF A;  5E8Q A;  4Q0D A;  1RA8 A;  3JW3 A;  3CL9 A;  3QLR A;  3EEJ A;  3L3R A;  1OHK A;  4PDJ A;  3NZ6 X;  5DFR A;  1DLR A;  3QYL A;  4KY4 A;  3KGY A;  3EEL A;  4NX6 A;  3FYW X;  4DPD A;  3FL9 A;  3QLS A;  3K45 A;  3NXY A;  3LG4 A;  4KFJ A;  4XEC X;  4I1N A;  1YHO A;  1IA2 A;  1S3U A;  2HQP A;  3DL6 A;  3JW5 A;  3SAI A;  4XT4 A;  3FQV A;  3DAT A;  4HA9 A;  1DR1 A;  2ANO A;  3KY8 A;  1PD8 A;  3FQO A;  5ECC A;  3QL0 A;  4NX7 A;  1DDR A;  4KNE A;  4CD2 A;  4KLX A;  3TD8 A;  1RA2 A;  4X5F A;  2C2T A;  2H2Q A;  4DDR A;  3SRW X;  1DRE A;  3KFY A;  2G6V A;  2B3Z A;  3SR5 X;  1RG7 A;  1DRH A;  1RX7 A;  1DR6 A;  1DR5 A;  3IRN A;  3EIG A;  3TQB A;  3KJS A;  1BZF A;  3CLB A;  1DR3 A;  1M79 A;  3F0S X;  3QFX A;  1S3Y A;  3UM8 A;  3NZB X;  3CSE A;  2W3V A;  4DFR A;  2AZN A;  4LAG X;  4DPH A;  3DAU A;  1VDR A;  2OBC A;  4FGH A;  1E26 A;  2FZI A;  4QLG A;  3F0U X;  4PST A;  3EEM A;  1RF7 A;  2INQ A;  3OAF A;  4EIL A;  1AI9 A;  4LEK X;  1IA3 A;  3SGY A;  4QJZ D;  1AO8 A;  2QK8 A;  3F8Z A;  1DRA A;  3M08 A;  1KLK A;  1HFQ A;  6DFR A;  5HI6 A;  3I8A X;  3DFR A;  3KJR A;  1U71 A;  2CIG A;  5JA3 A;  2XW7 A;  1DR4 A;  4FGG A;  5DXV A;  3RO9 A;  3S9U A;  3NXX A;  1DR7 A;  3SA1 A;  2W9H A;  4QLE A;  4Q67 A;  5JG0 X;  4HOG A;  5HUI A;  4QI9 A;  5HVB A;  2ZZA A;  2BLB A;  5HT5 A;  1JOL A;  1RX1 A;  1DIU A;  5HF2 X;  5CCC A;  1RA3 A;  4KY8 A;  4TU5 X;  4OR7 A;  4XRB A;  5HF0 X;  4XE6 X;  4G3M A;  1DRF A;  1DHI A;  1MVT A;  2FZH A;  2W3M A;  2BLC A;  2HXV A;  1AOE A;  1RD7 A;  3NXV A;  4GH8 A;  1DLS A;  3K74 A;  4M6J A;  1DRB A;  4X5H A;  3SA2 A;  4Q6A A;  4KM0 A;  3F0V X;  4X5J A;  1RE7 A;  1RA1 A;  4P3Q A;  3FRD X;  1MVS A;  1DYI A;  3FQC A;  1PD9 A;  1IA4 A;  4G95 A;  4H96 A;  5HVE A;  2W9S A;  1RB2 A;  1CZ3 A;  4KBN A;  1RX4 A;  4ELG A;  1DDS A;  1VJ3 A;  4XT6 A;  3DRC A;  3IRO A;  3JWC A;  5HT4 A;  3SRS X;  1KMV A;  1DYJ A;  4EIZ A;  1CD2 A;  4RGC A;  3I3R A;  3QLW A;  1S3V A;  3JSU A;  3F0B X;  3IA5 A;  2P4G A;  3JWK A;  1DYR A;  3SQY X;  2BL9 A;  2OIP A;  3GI2 A;  3QYO A;  1RX9 A;  5ECX A;  1DG5 A;  1RC4 A;  1S3W A;  5HQZ A;  3QG2 A;  1RH3 A;  3N0H A;  3FRE X;  3DL5 A;  5HPB A;  1J3J A;  1DF7 A;  3GHW A;  1DAJ A;  1RX8 A;  4M7U A;  3F91 A;  3FRB X;  1RB3 A;  4ECK A;  5HSR A;  3FQF A;  3FYV X;  4X5I A;  4P66 A;  4G8Z X;  3SRU X;  3VCO A;  1TDR A;  4HOF A;  4QHV A;  1M7A A;  2ANQ A;  1ZDR A;  3FQZ A;  4ELE A;  4P3R A;  4M2X A;  2DHF A;  1BOZ A;  1D1G A;  3NZ9 X;  3QL3 A;  1HFP A;  1OHJ A;  3FY8 X;  3NZA X;  3UM6 A;  4M6K A;  3IRM A;  3M09 A;  1DYH A;  2KGK A;  3F8Y A;  4PSS A;  4KJJ A;  4PTH A;  1M78 A;  3DGA A;  4IXF X;  4EIG A;  3K47 A;  1RX2 A;  3HJ3 A;  3R33 A;  3ZPC A;  3SRR X;  3IX9 A;  3F0Q X;  4OSG A;  1U70 A;  5U26 A;  4KJK A;  3GHV A;  3RG9 A;  4H97 A;  4Q0E A;  3ROA A;  2DRC A;  4PTJ A;  4XT8 A;  1LY3 A;  3IA4 A;  3NTZ A;  3QLZ A;  1IA1 A;  1J3I A;  1QZF A;  4P68 A;  2C2S A;  3K2H A;  1DIS A;  3NRR A;  1RX5 A;  3JWM A;  1LY4 A;  2JYB A;  1SEJ A;  3GHC A;  3SH2 A;  2ITH A;  5HQY A;  4KM2 A;  4FHB A;  1DR2 A;  3QLX A;  4QLF A;  2CD2 A;  3EEK A;  4EJ1 A;  3UM5 A;  3F0X X;  4HA7 A;  4I13 A;  3NXR A;  3S3V A;  2W3A A;  3JTW A;  3NZD A;  4M6L A;  1KMS A;  1U72 A;  4KAK A;  3D80 A;  1DHJ A;  2W3B A;  3NU0 A;  1DG8 A;  3FRA X;  3NZC X;  4KJL A;  3S7A A;  3QLY A;  2W9G A;  8DFR A;  3FS6 A;  4KD7 A;  1JUV A;  4H98 A;  4KEB A;  3DG8 A;  7DFR A;  4QJC A;  4LAH X;  3FY9 X;  2L28 A;  3INV A;  1HFR A;  3SRQ X;  4H95 A;  2FZJ A;  5CC9 A;  1J3K A;  3FQ0 A;  4DP3 A;  3QGT A;  4XT7 A;  3TQA A;  5U27 A;  1RX6 A;  2GD9 A;  4X5G A;  5EAJ A;  1PDB A;  4KYA A;  4HOE A;  2D5N A;  4PSY A;  3HBB A;  3GYF A;  3NXT A;  1LUD A;  4ELH A;  4KL9 A;  4IXE D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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