3D80A

Structural analysis of a holo enzyme complex of mouse dihydrofolate reductase with nadph and a ternary complex wtih the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine
Total Genus 51
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
186
structure length
186
Chain Sequence
VRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYEKKD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mus musculus
molecule keywords Dihydrofolate reductase
total genus 51
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3d80A00
3K47A 1BZFA 2G6VA 3D80A 4KYAA 1AO8A 3FRFX 3QLWA 4PSSA 3NXXA 3DL5A 1E26A 4IXED 1VDRA 3DL6A 4ELHA 3DATA 3IRMA 4KAKA 4RGCA 3EEKA 4IXFX 1PD8A 1RF7A 3GI2A 3M08A 3F0SX 4DP3A 3SA2A 2CD2A 2D0KA 1DF7A 3OCHA 1DISA 3EELA 4KLXA 3DAUA 3CD2A 3NXVA 5CC9A 3JTWA 3JVXA 4P68A 8DFRA 3NZDA 1DHIA 4KY4A 1HFRA 5HF0X 5FDAA 3UM6A 4KJJA 1DR6A 3EEJA 4PTJA 3EEMA 1DHFA 1DHJA 4XT5A 1RX5A 1M7AA 4P3QA 1QZFA 3DGAA 1HFPA 1RX1A 2D5NA 4XT4A 3QFXA 4G3MA 3TQBA 4H97A 3KGYA 5HT5A 3FQFA 3QLXA 1DR2A 1AI9A 3F0UX 1J3IA 1U71A 3DFRA 3TD8A 3SAIA 3QLRA 3CSEA 2W9GA 4Q67A 3QLSA 3QL0A 4QLFA 4FHBA 5ECXA 4DPHA 2BLCA 3KJRA 4H98A 2C2TA 2W3WA 5HQZA 1RX4A 3K2HA 3QYLA 4G8ZX 5HSRA 1M79A 2W9SA 2LF1A 3FRAX 1DG8A 1OHJA 4PDJA 2BLBA 4XT7A 1CZ3A 4EILA 4DDRA 3NXYA 4XT6A 3JWFA 1DYIA 4ELEA 3UM8A 3K74A 2L28A 1RX2A 1RX7A 3FQZA 2W9HA 3ZPGA 1DRAA 2O7PA 4M6KA 1ZDRA 1RA9A 1LY4A 3SQYX 3I3RA 5HVBA 1YHOA 4KJKA 5DXVA 4ELGA 1AOEA 4Q0EA 3EX8A 1HFQA 3SRWX 4QI9A 1M78A 3VCOA 4M6LA 3FY8X 2OBCA 3FQ0A 1RC4A 2HXVA 3QG2A 5CCCA 1IA4A 5HT4A 3FYWX 4EIZA 1DREA 4KM0A 5HUIA 3E0BA 3NTZA 1CD2A 3OAFA 3FREX 4IXGX 3F8ZA 5HVEA 4M6JA 4QHVA 4HA7A 4HOEA 1TDRA 1D1GA 2CIGA 1MVTA 1RD7A 2ANQA 3N0HA 3GHCA 2W3MA 4EJ1A 2KGKA 4X5HA 3SGYA 4GH8A 1S3UA 4KM2A 4CD2A 4G95A 3JW5A 1DDRA 2FZHA 4X5IA 2XW7A 2W3BA 3EIGA 1LY3A 3QYOA 3FRBX 3SRQX 3IRNA 1MVSA 1SEJA 3SRSX 1DRBA 4NX6A 4H95A 3FS6A 2HM9A 5U26A 4KFJA 1KMSA 3NZ9X 3F91A 1DIUA 3QGTA 1RX3A 3INVA 3L3RA 4HOGA 1DYJA 4OR7A 4I13A 1DDSA 2ITHA 1DR5A 1RA8A 2FZIA 3M09A 2GD9A 1VJ3A 4LAHX 3FY9X 1S3VA 3DG8A 3TQ9A 3UM5A 4KL9A 2W3VA 4LAEX 3TQ8A 3NZAX 5U27A 1KMVA 3GHWA 1LUDA 3SA1A 3CLBA 4QLEA 3SRUX 1U70A 2DHFA 4QLGA 2P4GA 2HQPA 1DG5A 2BL9A 3KFYA 3SH2A 1RX8A 1IA2A 3KY8A 1IA3A 3R33A 4DFRA 3NZCX 3I8AX 1DYHA 2W3AA 3NU0A 4Q6AA 2QK8A 1S3WA 2FZJA 1PD9A 1RA3A 4LEKX 3F0VX 1JOLA 2ANOA 1DRFA 4ELBA 3NXTA 4TU5X 3HJ3A 3FQOA 4FGHA 1U72A 3FRDX 1RX9A 1J3JA 3IROA 1J3KA 4NX7A 4KNEA 3NZBX 3ZPCA 4M2XA 3SRRX 4X5JA 1BOZA 3RG9A 1DLRA 3IX9A 4KBNA 3FQVA 1RE7A 4KY8A 4M7UA 3CL9A 4QJCA 1DAJA 4I1NA 4KEBA 2ZZAA 5HPBA 4ECKA 4XT8A 3F0BX 1RH3A 1DLSA 1DR7A 5HF2X 1OHKA 1RX6A 2INQA 3S9UA 2AZNA 3HBBA 5DFRA 5EAJA 1DR4A 3NXOA 3F8YA 3K45A 4P3RA 5HI6A 3NZ6X 1KLKA 1RA1A 4DPDA 3LG4A 1DG7A 3FYVX 4XRBA 1RA2A 3JWKA 3GYFA 3RO9A 1JOMA 3JW3A 5E8QA 2BLAA 3S7AA 3DRCA 3QLYA 4P66A 4HA9A 3TQAA 4KJLA 2H2QA 3KJSA 2OIPA 1RB2A 3FQCA 4LAGX 3D84X 4EIGA 3NRRA 3F0QX 4OSGA 4PTHA 4H96A 4XECX 1JUVA 3JSUA 3ROAA 2C2SA 3JWMA 2B3ZA 6DFRA 3NXRA 4HOFA 4PSYA 2JYBA 3F0XX 3IA4A 4QJZD 4M7VA 5JA3A 4X5FA 1DR3A 1PDBA 5HSUA 4KD7A 7DFRA 1IA1A 4X5GA 3S3VA 3SR5X 4PSTA 5JG0X 2DRCA 4ELFA 5HQYA 4XE6X 3GHVA 1DRHA 1DR1A 3JWCA 3FL8A 4FGGA 1RB3A 3QL3A 3QLZA 3IA5A 3FL9A 1DYRA 2W9TA 3Q1HA 1RG7A 4Q0DA 5ECCA 1S3YA
chains in the Genus database with same CATH superfamily
3K47A 1BZFA 2G6VA 3D80A 4KYAA 1AO8A 3FRFX 3QLWA 4PSSA 3NXXA 3DL5A 1E26A 4IXED 1VDRA 3DL6A 4ELHA 3DATA 3IRMA 4KAKA 4RGCA 3EEKA 4IXFX 1PD8A 1RF7A 3GI2A 3M08A 3F0SX 4DP3A 3SA2A 2CD2A 2D0KA 1DF7A 3OCHA 1DISA 3EELA 4KLXA 3DAUA 3CD2A 3NXVA 5CC9A 3JTWA 3JVXA 4P68A 8DFRA 3NZDA 1DHIA 4KY4A 1HFRA 5HF0X 5FDAA 3UM6A 4KJJA 1DR6A 3EEJA 4PTJA 3EEMA 1DHFA 1DHJA 4XT5A 1RX5A 1M7AA 4P3QA 1QZFA 3DGAA 1HFPA 1RX1A 2D5NA 4XT4A 3QFXA 4G3MA 3TQBA 4H97A 3KGYA 5HT5A 3FQFA 3QLXA 1DR2A 1AI9A 3F0UX 1J3IA 1U71A 3DFRA 3TD8A 3SAIA 3QLRA 3CSEA 2W9GA 4Q67A 3QLSA 3QL0A 4QLFA 4FHBA 5ECXA 4DPHA 2BLCA 3KJRA 4H98A 2C2TA 2W3WA 5HQZA 1RX4A 3K2HA 3QYLA 4G8ZX 5HSRA 1M79A 2W9SA 2LF1A 3FRAX 1DG8A 1OHJA 4PDJA 2BLBA 4XT7A 1CZ3A 4EILA 4DDRA 3NXYA 4XT6A 3JWFA 1DYIA 4ELEA 3UM8A 3K74A 2L28A 1RX2A 1RX7A 3FQZA 2W9HA 3ZPGA 1DRAA 2O7PA 4M6KA 1ZDRA 1RA9A 1LY4A 3SQYX 3I3RA 5HVBA 1YHOA 4KJKA 5DXVA 4ELGA 1AOEA 4Q0EA 3EX8A 1HFQA 3SRWX 4QI9A 1M78A 3VCOA 4M6LA 3FY8X 2OBCA 3FQ0A 1RC4A 2HXVA 3QG2A 5CCCA 1IA4A 5HT4A 3FYWX 4EIZA 1DREA 4KM0A 5HUIA 3E0BA 3NTZA 1CD2A 3OAFA 3FREX 4IXGX 3F8ZA 5HVEA 4M6JA 4QHVA 4HA7A 4HOEA 1TDRA 1D1GA 2CIGA 1MVTA 1RD7A 2ANQA 3N0HA 3GHCA 2W3MA 4EJ1A 2KGKA 4X5HA 3SGYA 4GH8A 1S3UA 4KM2A 4CD2A 4G95A 3JW5A 1DDRA 2FZHA 4X5IA 2XW7A 2W3BA 3EIGA 1LY3A 3QYOA 3FRBX 3SRQX 3IRNA 1MVSA 1SEJA 3SRSX 1DRBA 4NX6A 4H95A 3FS6A 2HM9A 5U26A 4KFJA 1KMSA 3NZ9X 3F91A 1DIUA 3QGTA 1RX3A 3INVA 3L3RA 4HOGA 1DYJA 4OR7A 4I13A 1DDSA 2ITHA 1DR5A 1RA8A 2FZIA 3M09A 2GD9A 1VJ3A 4LAHX 3FY9X 1S3VA 3DG8A 3TQ9A 3UM5A 4KL9A 2W3VA 4LAEX 3TQ8A 3NZAX 5U27A 1KMVA 3GHWA 1LUDA 3SA1A 3CLBA 4QLEA 3SRUX 1U70A 2DHFA 4QLGA 2P4GA 2HQPA 1DG5A 2BL9A 3KFYA 3SH2A 1RX8A 1IA2A 3KY8A 1IA3A 3R33A 4DFRA 3NZCX 3I8AX 1DYHA 2W3AA 3NU0A 4Q6AA 2QK8A 1S3WA 2FZJA 1PD9A 1RA3A 4LEKX 3F0VX 1JOLA 2ANOA 1DRFA 4ELBA 3NXTA 4TU5X 3HJ3A 3FQOA 4FGHA 1U72A 3FRDX 1RX9A 1J3JA 3IROA 1J3KA 4NX7A 4KNEA 3NZBX 3ZPCA 4M2XA 3SRRX 4X5JA 1BOZA 3RG9A 1DLRA 3IX9A 4KBNA 3FQVA 1RE7A 4KY8A 4M7UA 3CL9A 4QJCA 1DAJA 4I1NA 4KEBA 2ZZAA 5HPBA 4ECKA 4XT8A 3F0BX 1RH3A 1DLSA 1DR7A 5HF2X 1OHKA 1RX6A 2INQA 3S9UA 2AZNA 3HBBA 5DFRA 5EAJA 1DR4A 3NXOA 3F8YA 3K45A 4P3RA 5HI6A 3NZ6X 1KLKA 1RA1A 4DPDA 3LG4A 1DG7A 3FYVX 4XRBA 1RA2A 3JWKA 3GYFA 3RO9A 1JOMA 3JW3A 5E8QA 2BLAA 3S7AA 3DRCA 3QLYA 4P66A 4HA9A 3TQAA 4KJLA 2H2QA 3KJSA 2OIPA 1RB2A 3FQCA 4LAGX 3D84X 4EIGA 3NRRA 3F0QX 4OSGA 4PTHA 4H96A 4XECX 1JUVA 3JSUA 3ROAA 2C2SA 3JWMA 2B3ZA 6DFRA 3NXRA 4HOFA 4PSYA 2JYBA 3F0XX 3IA4A 4QJZD 4M7VA 5JA3A 4X5FA 1DR3A 1PDBA 5HSUA 4KD7A 7DFRA 1IA1A 4X5GA 3S3VA 3SR5X 4PSTA 5JG0X 2DRCA 4ELFA 5HQYA 4XE6X 3GHVA 1DRHA 1DR1A 3JWCA 3FL8A 4FGGA 1RB3A 3QL3A 3QLZA 3IA5A 3FL9A 1DYRA 2W9TA 3Q1HA 1RG7A 4Q0DA 5ECCA 1S3YA
chains in the Genus database with same CATH topology
3K47A 1BZFA 2G6VA 3D80A 4KYAA 1AO8A 3FRFX 3QLWA 4PSSA 3NXXA 3DL5A 1E26A 4IXED 1VDRA 3DL6A 4ELHA 3DATA 3IRMA 4KAKA 4RGCA 3EEKA 4IXFX 1PD8A 1RF7A 3GI2A 3M08A 3F0SX 4DP3A 3SA2A 2CD2A 2D0KA 1DF7A 3OCHA 1DISA 3EELA 4KLXA 3DAUA 3CD2A 3NXVA 5CC9A 3JTWA 3JVXA 4P68A 8DFRA 3NZDA 1DHIA 4KY4A 1HFRA 5HF0X 5FDAA 3UM6A 4KJJA 1DR6A 3EEJA 4PTJA 3EEMA 1DHFA 1DHJA 4XT5A 1RX5A 1M7AA 4P3QA 1QZFA 3DGAA 1HFPA 1RX1A 2D5NA 4XT4A 3QFXA 4G3MA 3TQBA 4H97A 3KGYA 5HT5A 3FQFA 3QLXA 1DR2A 1AI9A 3F0UX 1J3IA 1U71A 3DFRA 3TD8A 3SAIA 3QLRA 3CSEA 2W9GA 4Q67A 3QLSA 3QL0A 4QLFA 4FHBA 5ECXA 4DPHA 2BLCA 3KJRA 4H98A 2C2TA 2W3WA 5HQZA 1RX4A 3K2HA 3QYLA 4G8ZX 5HSRA 1M79A 2W9SA 2LF1A 3FRAX 1DG8A 1OHJA 4PDJA 2BLBA 4XT7A 1CZ3A 4EILA 4DDRA 3NXYA 4XT6A 3JWFA 1DYIA 4ELEA 3UM8A 3K74A 2L28A 1RX2A 1RX7A 3FQZA 2W9HA 3ZPGA 1DRAA 2O7PA 4M6KA 1ZDRA 1RA9A 1LY4A 3SQYX 3I3RA 5HVBA 1YHOA 4KJKA 5DXVA 4ELGA 1AOEA 4Q0EA 3EX8A 1HFQA 3SRWX 4QI9A 1M78A 3VCOA 4M6LA 3FY8X 2OBCA 3FQ0A 1RC4A 2HXVA 3QG2A 5CCCA 1IA4A 5HT4A 3FYWX 4EIZA 1DREA 4KM0A 5HUIA 3E0BA 3NTZA 1CD2A 3OAFA 3FREX 4IXGX 3F8ZA 5HVEA 4M6JA 4QHVA 4HA7A 4HOEA 1TDRA 1D1GA 2CIGA 1MVTA 1RD7A 2ANQA 3N0HA 3GHCA 2W3MA 4EJ1A 2KGKA 4X5HA 3SGYA 4GH8A 1S3UA 4KM2A 4CD2A 4G95A 3JW5A 1DDRA 2FZHA 4X5IA 2XW7A 2W3BA 3EIGA 1LY3A 3QYOA 3FRBX 3SRQX 3IRNA 1MVSA 1SEJA 3SRSX 1DRBA 4NX6A 4H95A 3FS6A 2HM9A 5U26A 4KFJA 1KMSA 3NZ9X 3F91A 1DIUA 3QGTA 1RX3A 3INVA 3L3RA 4HOGA 1DYJA 4OR7A 4I13A 1DDSA 2ITHA 1DR5A 1RA8A 2FZIA 3M09A 2GD9A 1VJ3A 4LAHX 3FY9X 1S3VA 3DG8A 3TQ9A 3UM5A 4KL9A 2W3VA 4LAEX 3TQ8A 3NZAX 5U27A 1KMVA 3GHWA 1LUDA 3SA1A 3CLBA 4QLEA 3SRUX 1U70A 2DHFA 4QLGA 2P4GA 2HQPA 1DG5A 2BL9A 3KFYA 3SH2A 1RX8A 1IA2A 3KY8A 1IA3A 3R33A 4DFRA 3NZCX 3I8AX 1DYHA 2W3AA 3NU0A 4Q6AA 2QK8A 1S3WA 2FZJA 1PD9A 1RA3A 4LEKX 3F0VX 1JOLA 2ANOA 1DRFA 4ELBA 3NXTA 4TU5X 3HJ3A 3FQOA 4FGHA 1U72A 3FRDX 1RX9A 1J3JA 3IROA 1J3KA 4NX7A 4KNEA 3NZBX 3ZPCA 4M2XA 3SRRX 4X5JA 1BOZA 3RG9A 1DLRA 3IX9A 4KBNA 3FQVA 1RE7A 4KY8A 4M7UA 3CL9A 4QJCA 1DAJA 4I1NA 4KEBA 2ZZAA 5HPBA 4ECKA 4XT8A 3F0BX 1RH3A 1DLSA 1DR7A 5HF2X 1OHKA 1RX6A 2INQA 3S9UA 2AZNA 3HBBA 5DFRA 5EAJA 1DR4A 3NXOA 3F8YA 3K45A 4P3RA 5HI6A 3NZ6X 1KLKA 1RA1A 4DPDA 3LG4A 1DG7A 3FYVX 4XRBA 1RA2A 3JWKA 3GYFA 3RO9A 1JOMA 3JW3A 5E8QA 2BLAA 3S7AA 3DRCA 3QLYA 4P66A 4HA9A 3TQAA 4KJLA 2H2QA 3KJSA 2OIPA 1RB2A 3FQCA 4LAGX 3D84X 4EIGA 3NRRA 3F0QX 4OSGA 4PTHA 4H96A 4XECX 1JUVA 3JSUA 3ROAA 2C2SA 3JWMA 2B3ZA 6DFRA 3NXRA 4HOFA 4PSYA 2JYBA 3F0XX 3IA4A 4QJZD 4M7VA 5JA3A 4X5FA 1DR3A 1PDBA 5HSUA 4KD7A 7DFRA 1IA1A 4X5GA 3S3VA 3SR5X 4PSTA 5JG0X 2DRCA 4ELFA 5HQYA 4XE6X 3GHVA 1DRHA 1DR1A 3JWCA 3FL8A 4FGGA 1RB3A 3QL3A 3QLZA 3IA5A 3FL9A 1DYRA 2W9TA 3Q1HA 1RG7A 4Q0DA 5ECCA 1S3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K47 A;  1BZF A;  2G6V A;  3D80 A;  4KYA A;  1AO8 A;  3FRF X;  3QLW A;  4PSS A;  3NXX A;  3DL5 A;  1E26 A;  4IXE D;  1VDR A;  3DL6 A;  4ELH A;  3DAT A;  3IRM A;  4KAK A;  4RGC A;  3EEK A;  4IXF X;  1PD8 A;  1RF7 A;  3GI2 A;  3M08 A;  3F0S X;  4DP3 A;  3SA2 A;  2CD2 A;  2D0K A;  1DF7 A;  3OCH A;  1DIS A;  3EEL A;  4KLX A;  3DAU A;  3CD2 A;  3NXV A;  5CC9 A;  3JTW A;  3JVX A;  4P68 A;  8DFR A;  3NZD A;  1DHI A;  4KY4 A;  1HFR A;  5HF0 X;  5FDA A;  3UM6 A;  4KJJ A;  1DR6 A;  3EEJ A;  4PTJ A;  3EEM A;  1DHF A;  1DHJ A;  4XT5 A;  1RX5 A;  1M7A A;  4P3Q A;  1QZF A;  3DGA A;  1HFP A;  1RX1 A;  2D5N A;  4XT4 A;  3QFX A;  4G3M A;  3TQB A;  4H97 A;  3KGY A;  5HT5 A;  3FQF A;  3QLX A;  1DR2 A;  1AI9 A;  3F0U X;  1J3I A;  1U71 A;  3DFR A;  3TD8 A;  3SAI A;  3QLR A;  3CSE A;  2W9G A;  4Q67 A;  3QLS A;  3QL0 A;  4QLF A;  4FHB A;  5ECX A;  4DPH A;  2BLC A;  3KJR A;  4H98 A;  2C2T A;  2W3W A;  5HQZ A;  1RX4 A;  3K2H A;  3QYL A;  4G8Z X;  5HSR A;  1M79 A;  2W9S A;  2LF1 A;  3FRA X;  1DG8 A;  1OHJ A;  4PDJ A;  2BLB A;  4XT7 A;  1CZ3 A;  4EIL A;  4DDR A;  3NXY A;  4XT6 A;  3JWF A;  1DYI A;  4ELE A;  3UM8 A;  3K74 A;  2L28 A;  1RX2 A;  1RX7 A;  3FQZ A;  2W9H A;  3ZPG A;  1DRA A;  2O7P A;  4M6K A;  1ZDR A;  1RA9 A;  1LY4 A;  3SQY X;  3I3R A;  5HVB A;  1YHO A;  4KJK A;  5DXV A;  4ELG A;  1AOE A;  4Q0E A;  3EX8 A;  1HFQ A;  3SRW X;  4QI9 A;  1M78 A;  3VCO A;  4M6L A;  3FY8 X;  2OBC A;  3FQ0 A;  1RC4 A;  2HXV A;  3QG2 A;  5CCC A;  1IA4 A;  5HT4 A;  3FYW X;  4EIZ A;  1DRE A;  4KM0 A;  5HUI A;  3E0B A;  3NTZ A;  1CD2 A;  3OAF A;  3FRE X;  4IXG X;  3F8Z A;  5HVE A;  4M6J A;  4QHV A;  4HA7 A;  4HOE A;  1TDR A;  1D1G A;  2CIG A;  1MVT A;  1RD7 A;  2ANQ A;  3N0H A;  3GHC A;  2W3M A;  4EJ1 A;  2KGK A;  4X5H A;  3SGY A;  4GH8 A;  1S3U A;  4KM2 A;  4CD2 A;  4G95 A;  3JW5 A;  1DDR A;  2FZH A;  4X5I A;  2XW7 A;  2W3B A;  3EIG A;  1LY3 A;  3QYO A;  3FRB X;  3SRQ X;  3IRN A;  1MVS A;  1SEJ A;  3SRS X;  1DRB A;  4NX6 A;  4H95 A;  3FS6 A;  2HM9 A;  5U26 A;  4KFJ A;  1KMS A;  3NZ9 X;  3F91 A;  1DIU A;  3QGT A;  1RX3 A;  3INV A;  3L3R A;  4HOG A;  1DYJ A;  4OR7 A;  4I13 A;  1DDS A;  2ITH A;  1DR5 A;  1RA8 A;  2FZI A;  3M09 A;  2GD9 A;  1VJ3 A;  4LAH X;  3FY9 X;  1S3V A;  3DG8 A;  3TQ9 A;  3UM5 A;  4KL9 A;  2W3V A;  4LAE X;  3TQ8 A;  3NZA X;  5U27 A;  1KMV A;  3GHW A;  1LUD A;  3SA1 A;  3CLB A;  4QLE A;  3SRU X;  1U70 A;  2DHF A;  4QLG A;  2P4G A;  2HQP A;  1DG5 A;  2BL9 A;  3KFY A;  3SH2 A;  1RX8 A;  1IA2 A;  3KY8 A;  1IA3 A;  3R33 A;  4DFR A;  3NZC X;  3I8A X;  1DYH A;  2W3A A;  3NU0 A;  4Q6A A;  2QK8 A;  1S3W A;  2FZJ A;  1PD9 A;  1RA3 A;  4LEK X;  3F0V X;  1JOL A;  2ANO A;  1DRF A;  4ELB A;  3NXT A;  4TU5 X;  3HJ3 A;  3FQO A;  4FGH A;  1U72 A;  3FRD X;  1RX9 A;  1J3J A;  3IRO A;  1J3K A;  4NX7 A;  4KNE A;  3NZB X;  3ZPC A;  4M2X A;  3SRR X;  4X5J A;  1BOZ A;  3RG9 A;  1DLR A;  3IX9 A;  4KBN A;  3FQV A;  1RE7 A;  4KY8 A;  4M7U A;  3CL9 A;  4QJC A;  1DAJ A;  4I1N A;  4KEB A;  2ZZA A;  5HPB A;  4ECK A;  4XT8 A;  3F0B X;  1RH3 A;  1DLS A;  1DR7 A;  5HF2 X;  1OHK A;  1RX6 A;  2INQ A;  3S9U A;  2AZN A;  3HBB A;  5DFR A;  5EAJ A;  1DR4 A;  3NXO A;  3F8Y A;  3K45 A;  4P3R A;  5HI6 A;  3NZ6 X;  1KLK A;  1RA1 A;  4DPD A;  3LG4 A;  1DG7 A;  3FYV X;  4XRB A;  1RA2 A;  3JWK A;  3GYF A;  3RO9 A;  1JOM A;  3JW3 A;  5E8Q A;  2BLA A;  3S7A A;  3DRC A;  3QLY A;  4P66 A;  4HA9 A;  3TQA A;  4KJL A;  2H2Q A;  3KJS A;  2OIP A;  1RB2 A;  3FQC A;  4LAG X;  3D84 X;  4EIG A;  3NRR A;  3F0Q X;  4OSG A;  4PTH A;  4H96 A;  4XEC X;  1JUV A;  3JSU A;  3ROA A;  2C2S A;  3JWM A;  2B3Z A;  6DFR A;  3NXR A;  4HOF A;  4PSY A;  2JYB A;  3F0X X;  3IA4 A;  4QJZ D;  4M7V A;  5JA3 A;  4X5F A;  1DR3 A;  1PDB A;  5HSU A;  4KD7 A;  7DFR A;  1IA1 A;  4X5G A;  3S3V A;  3SR5 X;  4PST A;  5JG0 X;  2DRC A;  4ELF A;  5HQY A;  4XE6 X;  3GHV A;  1DRH A;  1DR1 A;  3JWC A;  3FL8 A;  4FGG A;  1RB3 A;  3QL3 A;  3QLZ A;  3IA5 A;  3FL9 A;  1DYR A;  2W9T A;  3Q1H A;  1RG7 A;  4Q0D A;  5ECC A;  1S3Y A; 
#chains in the Genus database with same CATH topology
 3K47 A;  1BZF A;  2G6V A;  3D80 A;  4KYA A;  1AO8 A;  3FRF X;  3QLW A;  4PSS A;  3NXX A;  3DL5 A;  1E26 A;  4IXE D;  1VDR A;  3DL6 A;  4ELH A;  3DAT A;  3IRM A;  4KAK A;  4RGC A;  3EEK A;  4IXF X;  1PD8 A;  1RF7 A;  3GI2 A;  3M08 A;  3F0S X;  4DP3 A;  3SA2 A;  2CD2 A;  2D0K A;  1DF7 A;  3OCH A;  1DIS A;  3EEL A;  4KLX A;  3DAU A;  3CD2 A;  3NXV A;  5CC9 A;  3JTW A;  3JVX A;  4P68 A;  8DFR A;  3NZD A;  1DHI A;  4KY4 A;  1HFR A;  5HF0 X;  5FDA A;  3UM6 A;  4KJJ A;  1DR6 A;  3EEJ A;  4PTJ A;  3EEM A;  1DHF A;  1DHJ A;  4XT5 A;  1RX5 A;  1M7A A;  4P3Q A;  1QZF A;  3DGA A;  1HFP A;  1RX1 A;  2D5N A;  4XT4 A;  3QFX A;  4G3M A;  3TQB A;  4H97 A;  3KGY A;  5HT5 A;  3FQF A;  3QLX A;  1DR2 A;  1AI9 A;  3F0U X;  1J3I A;  1U71 A;  3DFR A;  3TD8 A;  3SAI A;  3QLR A;  3CSE A;  2W9G A;  4Q67 A;  3QLS A;  3QL0 A;  4QLF A;  4FHB A;  5ECX A;  4DPH A;  2BLC A;  3KJR A;  4H98 A;  2C2T A;  2W3W A;  5HQZ A;  1RX4 A;  3K2H A;  3QYL A;  4G8Z X;  5HSR A;  1M79 A;  2W9S A;  2LF1 A;  3FRA X;  1DG8 A;  1OHJ A;  4PDJ A;  2BLB A;  4XT7 A;  1CZ3 A;  4EIL A;  4DDR A;  3NXY A;  4XT6 A;  3JWF A;  1DYI A;  4ELE A;  3UM8 A;  3K74 A;  2L28 A;  1RX2 A;  1RX7 A;  3FQZ A;  2W9H A;  3ZPG A;  1DRA A;  2O7P A;  4M6K A;  1ZDR A;  1RA9 A;  1LY4 A;  3SQY X;  3I3R A;  5HVB A;  1YHO A;  4KJK A;  5DXV A;  4ELG A;  1AOE A;  4Q0E A;  3EX8 A;  1HFQ A;  3SRW X;  4QI9 A;  1M78 A;  3VCO A;  4M6L A;  3FY8 X;  2OBC A;  3FQ0 A;  1RC4 A;  2HXV A;  3QG2 A;  5CCC A;  1IA4 A;  5HT4 A;  3FYW X;  4EIZ A;  1DRE A;  4KM0 A;  5HUI A;  3E0B A;  3NTZ A;  1CD2 A;  3OAF A;  3FRE X;  4IXG X;  3F8Z A;  5HVE A;  4M6J A;  4QHV A;  4HA7 A;  4HOE A;  1TDR A;  1D1G A;  2CIG A;  1MVT A;  1RD7 A;  2ANQ A;  3N0H A;  3GHC A;  2W3M A;  4EJ1 A;  2KGK A;  4X5H A;  3SGY A;  4GH8 A;  1S3U A;  4KM2 A;  4CD2 A;  4G95 A;  3JW5 A;  1DDR A;  2FZH A;  4X5I A;  2XW7 A;  2W3B A;  3EIG A;  1LY3 A;  3QYO A;  3FRB X;  3SRQ X;  3IRN A;  1MVS A;  1SEJ A;  3SRS X;  1DRB A;  4NX6 A;  4H95 A;  3FS6 A;  2HM9 A;  5U26 A;  4KFJ A;  1KMS A;  3NZ9 X;  3F91 A;  1DIU A;  3QGT A;  1RX3 A;  3INV A;  3L3R A;  4HOG A;  1DYJ A;  4OR7 A;  4I13 A;  1DDS A;  2ITH A;  1DR5 A;  1RA8 A;  2FZI A;  3M09 A;  2GD9 A;  1VJ3 A;  4LAH X;  3FY9 X;  1S3V A;  3DG8 A;  3TQ9 A;  3UM5 A;  4KL9 A;  2W3V A;  4LAE X;  3TQ8 A;  3NZA X;  5U27 A;  1KMV A;  3GHW A;  1LUD A;  3SA1 A;  3CLB A;  4QLE A;  3SRU X;  1U70 A;  2DHF A;  4QLG A;  2P4G A;  2HQP A;  1DG5 A;  2BL9 A;  3KFY A;  3SH2 A;  1RX8 A;  1IA2 A;  3KY8 A;  1IA3 A;  3R33 A;  4DFR A;  3NZC X;  3I8A X;  1DYH A;  2W3A A;  3NU0 A;  4Q6A A;  2QK8 A;  1S3W A;  2FZJ A;  1PD9 A;  1RA3 A;  4LEK X;  3F0V X;  1JOL A;  2ANO A;  1DRF A;  4ELB A;  3NXT A;  4TU5 X;  3HJ3 A;  3FQO A;  4FGH A;  1U72 A;  3FRD X;  1RX9 A;  1J3J A;  3IRO A;  1J3K A;  4NX7 A;  4KNE A;  3NZB X;  3ZPC A;  4M2X A;  3SRR X;  4X5J A;  1BOZ A;  3RG9 A;  1DLR A;  3IX9 A;  4KBN A;  3FQV A;  1RE7 A;  4KY8 A;  4M7U A;  3CL9 A;  4QJC A;  1DAJ A;  4I1N A;  4KEB A;  2ZZA A;  5HPB A;  4ECK A;  4XT8 A;  3F0B X;  1RH3 A;  1DLS A;  1DR7 A;  5HF2 X;  1OHK A;  1RX6 A;  2INQ A;  3S9U A;  2AZN A;  3HBB A;  5DFR A;  5EAJ A;  1DR4 A;  3NXO A;  3F8Y A;  3K45 A;  4P3R A;  5HI6 A;  3NZ6 X;  1KLK A;  1RA1 A;  4DPD A;  3LG4 A;  1DG7 A;  3FYV X;  4XRB A;  1RA2 A;  3JWK A;  3GYF A;  3RO9 A;  1JOM A;  3JW3 A;  5E8Q A;  2BLA A;  3S7A A;  3DRC A;  3QLY A;  4P66 A;  4HA9 A;  3TQA A;  4KJL A;  2H2Q A;  3KJS A;  2OIP A;  1RB2 A;  3FQC A;  4LAG X;  3D84 X;  4EIG A;  3NRR A;  3F0Q X;  4OSG A;  4PTH A;  4H96 A;  4XEC X;  1JUV A;  3JSU A;  3ROA A;  2C2S A;  3JWM A;  2B3Z A;  6DFR A;  3NXR A;  4HOF A;  4PSY A;  2JYB A;  3F0X X;  3IA4 A;  4QJZ D;  4M7V A;  5JA3 A;  4X5F A;  1DR3 A;  1PDB A;  5HSU A;  4KD7 A;  7DFR A;  1IA1 A;  4X5G A;  3S3V A;  3SR5 X;  4PST A;  5JG0 X;  2DRC A;  4ELF A;  5HQY A;  4XE6 X;  3GHV A;  1DRH A;  1DR1 A;  3JWC A;  3FL8 A;  4FGG A;  1RB3 A;  3QL3 A;  3QLZ A;  3IA5 A;  3FL9 A;  1DYR A;  2W9T A;  3Q1H A;  1RG7 A;  4Q0D A;  5ECC A;  1S3Y A; 
#chains in the Genus database with same CATH homology
 3K47 A;  1BZF A;  2G6V A;  3D80 A;  4KYA A;  1AO8 A;  3FRF X;  3QLW A;  4PSS A;  3NXX A;  3DL5 A;  1E26 A;  4IXE D;  1VDR A;  3DL6 A;  4ELH A;  3DAT A;  3IRM A;  4KAK A;  4RGC A;  3EEK A;  4IXF X;  1PD8 A;  1RF7 A;  3GI2 A;  3M08 A;  3F0S X;  4DP3 A;  3SA2 A;  2CD2 A;  2D0K A;  1DF7 A;  3OCH A;  1DIS A;  3EEL A;  4KLX A;  3DAU A;  3CD2 A;  3NXV A;  5CC9 A;  3JTW A;  3JVX A;  4P68 A;  8DFR A;  3NZD A;  1DHI A;  4KY4 A;  1HFR A;  5HF0 X;  5FDA A;  3UM6 A;  4KJJ A;  1DR6 A;  3EEJ A;  4PTJ A;  3EEM A;  1DHF A;  1DHJ A;  4XT5 A;  1RX5 A;  1M7A A;  4P3Q A;  1QZF A;  3DGA A;  1HFP A;  1RX1 A;  2D5N A;  4XT4 A;  3QFX A;  4G3M A;  3TQB A;  4H97 A;  3KGY A;  5HT5 A;  3FQF A;  3QLX A;  1DR2 A;  1AI9 A;  3F0U X;  1J3I A;  1U71 A;  3DFR A;  3TD8 A;  3SAI A;  3QLR A;  3CSE A;  2W9G A;  4Q67 A;  3QLS A;  3QL0 A;  4QLF A;  4FHB A;  5ECX A;  4DPH A;  2BLC A;  3KJR A;  4H98 A;  2C2T A;  2W3W A;  5HQZ A;  1RX4 A;  3K2H A;  3QYL A;  4G8Z X;  5HSR A;  1M79 A;  2W9S A;  2LF1 A;  3FRA X;  1DG8 A;  1OHJ A;  4PDJ A;  2BLB A;  4XT7 A;  1CZ3 A;  4EIL A;  4DDR A;  3NXY A;  4XT6 A;  3JWF A;  1DYI A;  4ELE A;  3UM8 A;  3K74 A;  2L28 A;  1RX2 A;  1RX7 A;  3FQZ A;  2W9H A;  3ZPG A;  1DRA A;  2O7P A;  4M6K A;  1ZDR A;  1RA9 A;  1LY4 A;  3SQY X;  3I3R A;  5HVB A;  1YHO A;  4KJK A;  5DXV A;  4ELG A;  1AOE A;  4Q0E A;  3EX8 A;  1HFQ A;  3SRW X;  4QI9 A;  1M78 A;  3VCO A;  4M6L A;  3FY8 X;  2OBC A;  3FQ0 A;  1RC4 A;  2HXV A;  3QG2 A;  5CCC A;  1IA4 A;  5HT4 A;  3FYW X;  4EIZ A;  1DRE A;  4KM0 A;  5HUI A;  3E0B A;  3NTZ A;  1CD2 A;  3OAF A;  3FRE X;  4IXG X;  3F8Z A;  5HVE A;  4M6J A;  4QHV A;  4HA7 A;  4HOE A;  1TDR A;  1D1G A;  2CIG A;  1MVT A;  1RD7 A;  2ANQ A;  3N0H A;  3GHC A;  2W3M A;  4EJ1 A;  2KGK A;  4X5H A;  3SGY A;  4GH8 A;  1S3U A;  4KM2 A;  4CD2 A;  4G95 A;  3JW5 A;  1DDR A;  2FZH A;  4X5I A;  2XW7 A;  2W3B A;  3EIG A;  1LY3 A;  3QYO A;  3FRB X;  3SRQ X;  3IRN A;  1MVS A;  1SEJ A;  3SRS X;  1DRB A;  4NX6 A;  4H95 A;  3FS6 A;  2HM9 A;  5U26 A;  4KFJ A;  1KMS A;  3NZ9 X;  3F91 A;  1DIU A;  3QGT A;  1RX3 A;  3INV A;  3L3R A;  4HOG A;  1DYJ A;  4OR7 A;  4I13 A;  1DDS A;  2ITH A;  1DR5 A;  1RA8 A;  2FZI A;  3M09 A;  2GD9 A;  1VJ3 A;  4LAH X;  3FY9 X;  1S3V A;  3DG8 A;  3TQ9 A;  3UM5 A;  4KL9 A;  2W3V A;  4LAE X;  3TQ8 A;  3NZA X;  5U27 A;  1KMV A;  3GHW A;  1LUD A;  3SA1 A;  3CLB A;  4QLE A;  3SRU X;  1U70 A;  2DHF A;  4QLG A;  2P4G A;  2HQP A;  1DG5 A;  2BL9 A;  3KFY A;  3SH2 A;  1RX8 A;  1IA2 A;  3KY8 A;  1IA3 A;  3R33 A;  4DFR A;  3NZC X;  3I8A X;  1DYH A;  2W3A A;  3NU0 A;  4Q6A A;  2QK8 A;  1S3W A;  2FZJ A;  1PD9 A;  1RA3 A;  4LEK X;  3F0V X;  1JOL A;  2ANO A;  1DRF A;  4ELB A;  3NXT A;  4TU5 X;  3HJ3 A;  3FQO A;  4FGH A;  1U72 A;  3FRD X;  1RX9 A;  1J3J A;  3IRO A;  1J3K A;  4NX7 A;  4KNE A;  3NZB X;  3ZPC A;  4M2X A;  3SRR X;  4X5J A;  1BOZ A;  3RG9 A;  1DLR A;  3IX9 A;  4KBN A;  3FQV A;  1RE7 A;  4KY8 A;  4M7U A;  3CL9 A;  4QJC A;  1DAJ A;  4I1N A;  4KEB A;  2ZZA A;  5HPB A;  4ECK A;  4XT8 A;  3F0B X;  1RH3 A;  1DLS A;  1DR7 A;  5HF2 X;  1OHK A;  1RX6 A;  2INQ A;  3S9U A;  2AZN A;  3HBB A;  5DFR A;  5EAJ A;  1DR4 A;  3NXO A;  3F8Y A;  3K45 A;  4P3R A;  5HI6 A;  3NZ6 X;  1KLK A;  1RA1 A;  4DPD A;  3LG4 A;  1DG7 A;  3FYV X;  4XRB A;  1RA2 A;  3JWK A;  3GYF A;  3RO9 A;  1JOM A;  3JW3 A;  5E8Q A;  2BLA A;  3S7A A;  3DRC A;  3QLY A;  4P66 A;  4HA9 A;  3TQA A;  4KJL A;  2H2Q A;  3KJS A;  2OIP A;  1RB2 A;  3FQC A;  4LAG X;  3D84 X;  4EIG A;  3NRR A;  3F0Q X;  4OSG A;  4PTH A;  4H96 A;  4XEC X;  1JUV A;  3JSU A;  3ROA A;  2C2S A;  3JWM A;  2B3Z A;  6DFR A;  3NXR A;  4HOF A;  4PSY A;  2JYB A;  3F0X X;  3IA4 A;  4QJZ D;  4M7V A;  5JA3 A;  4X5F A;  1DR3 A;  1PDB A;  5HSU A;  4KD7 A;  7DFR A;  1IA1 A;  4X5G A;  3S3V A;  3SR5 X;  4PST A;  5JG0 X;  2DRC A;  4ELF A;  5HQY A;  4XE6 X;  3GHV A;  1DRH A;  1DR1 A;  3JWC A;  3FL8 A;  4FGG A;  1RB3 A;  3QL3 A;  3QLZ A;  3IA5 A;  3FL9 A;  1DYR A;  2W9T A;  3Q1H A;  1RG7 A;  4Q0D A;  5ECC A;  1S3Y A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...