3DRCA

Investigation of the functional role of tryptophan-22 in escherichia coli dihydrofolate reductase by site-directed mutagenesis
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 44
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1992-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3drcA00
3FQ0A 4G8ZX 6DFRA 4KY4A 1KMSA 3NU0A 1QZFA 3QLYA 3IROA 1DR5A 3JWFA 3OCHA 2XW7A 3K45A 3CLBA 1M7AA 4PSTA 3CSEA 1S3UA 4HOEA 1RE7A 2W9SA 3NXOA 4DDRA 3SRSX 1DLRA 3FQVA 3FY9X 4XT7A 5HVBA 4DP3A 4OR7A 3FYVX 2P4GA 1HFRA 4P68A 3UM8A 3DG8A 3SH2A 1DAJA 4ELFA 1LY3A 4KBNA 3NZBX 2INQA 4EIZA 4RGCA 4LAGX 3KY8A 3F0XX 4KJKA 4XE6X 1JOLA 4M6LA 3I3RA 3FQCA 4XT4A 1J3KA 1CD2A 3JWKA 1DIUA 3EX8A 3DAUA 3NZ6X 3NZAX 4M7VA 3KGYA 3FQOA 3UM6A 4PSYA 3DRCA 1DR7A 5FDAA 1DHJA 2CD2A 3HBBA 3EIGA 3GHWA 1DISA 4KY8A 4X5HA 5CCCA 5U27A 4DFRA 1J3JA 3I8AX 3CL9A 3JTWA 4LAEX 3Q1HA 3KFYA 4KLXA 5E8QA 3VCOA 4KM0A 1DYRA 3JWCA 4HOFA 3NXYA 4H95A 5HUIA 3KJRA 1AOEA 3IX9A 3EEJA 1RB3A 2BLAA 1RX7A 1RG7A 1RF7A 1RX1A 1OHJA 1RC4A 2ZZAA 1RX2A 3JW5A 3KJSA 4M7UA 1BOZA 3NRRA 3SRWX 4HA9A 2KGKA 2W3MA 4IXGX 4M6KA 4DPHA 3IA5A 1J3IA 1DYHA 1JOMA 2ANOA 2CIGA 3NZDA 1RX8A 3QFXA 3FL8A 2FZHA 5HT5A 3F0SX 1RX5A 1DREA 3EEMA 3IRMA 4PTJA 3D84X 3SRUX 1AO8A 3F0UX 1HFPA 2C2SA 4H96A 1S3WA 4H97A 4X5GA 3TQ8A 4ELHA 4KL9A 5CC9A 5HVEA 5HI6A 3K2HA 1DR6A 1PD9A 4ELGA 2BL9A 5DFRA 4G3MA 3EELA 1YHOA 3DL6A 3EEKA 1M78A 4KEBA 2DHFA 3N0HA 1U70A 3QYLA 3TQ9A 4QLFA 4XT8A 5HSRA 4QJZD 3DFRA 2HXVA 3FS6A 3JWMA 4FGHA 1RA9A 2DRCA 2FZJA 4PSSA 1DR4A 3NZ9X 4KM2A 4Q0EA 3SQYX 1RX3A 3QL3A 5HSUA 2ANQA 4X5JA 3IA4A 4QHVA 1DG7A 4FGGA 1U71A 3SRQX 3QLWA 1IA4A 1PDBA 1RA2A 1RD7A 1JUVA 4NX6A 3FYWX 5EAJA 3QLXA 3FRAX 3GI2A 1IA1A 4IXFX 3S3VA 5HF2X 1PD8A 3QLSA 1RB2A 2OBCA 1RX4A 2BLCA 2C2TA 2AZNA 3DL5A 1RX9A 4ELEA 1IA2A 5HF0X 1S3VA 3NXXA 1KLKA 3TD8A 2OIPA 3K47A 1DRBA 3QGTA 3HJ3A 3F0VX 4IXED 1M79A 1RA8A 3FQFA 2G6VA 1DDRA 3F0BX 4KJJA 4EILA 3RG9A 3F8YA 4LAHX 1S3YA 4PTHA 3JW3A 2LF1A 5DXVA 3K74A 4OSGA 4QLEA 4G95A 1VDRA 3CD2A 4M2XA 3NXRA 1DR1A 1DDSA 1TDRA 1LY4A 3JVXA 4KD7A 2BLBA 1DHFA 2W9GA 3INVA 5ECCA 4KFJA 3GYFA 2ITHA 1DYJA 4XECX 1KMVA 1DG5A 4H98A 1IA3A 3QL0A 4P3RA 3R33A 4M6JA 3TQAA 2W3VA 3GHVA 4Q0DA 3S9UA 1DRHA 4QJCA 3SGYA 3NZCX 4XRBA 1DR3A 3JSUA 4CD2A 4ELBA 1BZFA 3LG4A 1LUDA 3NXTA 1RA3A 1DHIA 2QK8A 2W3BA 3E0BA 2B3ZA 3OAFA 3FREX 5HQYA 3F91A 3D80A 4X5IA 4TU5X 5HQZA 2D0KA 5HT4A 1DF7A 3FY8X 3SR5X 1SEJA 4P66A 4X5FA 4XT6A 1DRAA 1AI9A 2W3WA 3IRNA 1RA1A 5U26A 1MVSA 1DRFA 3NTZA 1DR2A 3SAIA 2D5NA 4KYAA 4HA7A 4HOGA 1VJ3A 1DYIA 2HM9A 2L28A 1HFQA 3M09A 2HQPA 2W3AA 8DFRA 4KJLA 4EJ1A 4GH8A 3S7AA 1CZ3A 3F0QX 3TQBA 3DGAA 1D1GA 4QI9A 4KAKA 1DLSA 3FRBX 4XT5A 2GD9A 4FHBA 3M08A 1ZDRA 3ZPGA 3UM5A 2W9TA 3SA2A 3F8ZA 3ZPCA 1DG8A 3DATA 2JYBA 3SRRX 2W9HA 2H2QA 5ECXA 3FRFX 3SA1A 1OHKA 3QLRA 4LEKX 4Q6AA 3FRDX 1RH3A 5JG0X 5HPBA 3ROAA 4I13A 4KNEA 3QG2A 2FZIA 4PDJA 3FL9A 3GHCA 4DPDA 3L3RA 7DFRA 2O7PA 3QYOA 3NXVA 1RX6A 4NX7A 4EIGA 4P3QA 1MVTA 4I1NA 3RO9A 4ECKA 4Q67A 4QLGA 5JA3A 3QLZA 3FQZA 1E26A 1U72A
chains in the Genus database with same CATH superfamily
3FQ0A 4G8ZX 6DFRA 4KY4A 1KMSA 3NU0A 1QZFA 3QLYA 3IROA 1DR5A 3JWFA 3OCHA 2XW7A 3K45A 3CLBA 1M7AA 4PSTA 3CSEA 1S3UA 4HOEA 1RE7A 2W9SA 3NXOA 4DDRA 3SRSX 1DLRA 3FQVA 3FY9X 4XT7A 5HVBA 4DP3A 4OR7A 3FYVX 2P4GA 1HFRA 4P68A 3UM8A 3DG8A 3SH2A 1DAJA 4ELFA 1LY3A 4KBNA 3NZBX 2INQA 4EIZA 4RGCA 4LAGX 3KY8A 3F0XX 4KJKA 4XE6X 1JOLA 4M6LA 3I3RA 3FQCA 4XT4A 1J3KA 1CD2A 3JWKA 1DIUA 3EX8A 3DAUA 3NZ6X 3NZAX 4M7VA 3KGYA 3FQOA 3UM6A 4PSYA 3DRCA 1DR7A 5FDAA 1DHJA 2CD2A 3HBBA 3EIGA 3GHWA 1DISA 4KY8A 4X5HA 5CCCA 5U27A 4DFRA 1J3JA 3I8AX 3CL9A 3JTWA 4LAEX 3Q1HA 3KFYA 4KLXA 5E8QA 3VCOA 4KM0A 1DYRA 3JWCA 4HOFA 3NXYA 4H95A 5HUIA 3KJRA 1AOEA 3IX9A 3EEJA 1RB3A 2BLAA 1RX7A 1RG7A 1RF7A 1RX1A 1OHJA 1RC4A 2ZZAA 1RX2A 3JW5A 3KJSA 4M7UA 1BOZA 3NRRA 3SRWX 4HA9A 2KGKA 2W3MA 4IXGX 4M6KA 4DPHA 3IA5A 1J3IA 1DYHA 1JOMA 2ANOA 2CIGA 3NZDA 1RX8A 3QFXA 3FL8A 2FZHA 5HT5A 3F0SX 1RX5A 1DREA 3EEMA 3IRMA 4PTJA 3D84X 3SRUX 1AO8A 3F0UX 1HFPA 2C2SA 4H96A 1S3WA 4H97A 4X5GA 3TQ8A 4ELHA 4KL9A 5CC9A 5HVEA 5HI6A 3K2HA 1DR6A 1PD9A 4ELGA 2BL9A 5DFRA 4G3MA 3EELA 1YHOA 3DL6A 3EEKA 1M78A 4KEBA 2DHFA 3N0HA 1U70A 3QYLA 3TQ9A 4QLFA 4XT8A 5HSRA 4QJZD 3DFRA 2HXVA 3FS6A 3JWMA 4FGHA 1RA9A 2DRCA 2FZJA 4PSSA 1DR4A 3NZ9X 4KM2A 4Q0EA 3SQYX 1RX3A 3QL3A 5HSUA 2ANQA 4X5JA 3IA4A 4QHVA 1DG7A 4FGGA 1U71A 3SRQX 3QLWA 1IA4A 1PDBA 1RA2A 1RD7A 1JUVA 4NX6A 3FYWX 5EAJA 3QLXA 3FRAX 3GI2A 1IA1A 4IXFX 3S3VA 5HF2X 1PD8A 3QLSA 1RB2A 2OBCA 1RX4A 2BLCA 2C2TA 2AZNA 3DL5A 1RX9A 4ELEA 1IA2A 5HF0X 1S3VA 3NXXA 1KLKA 3TD8A 2OIPA 3K47A 1DRBA 3QGTA 3HJ3A 3F0VX 4IXED 1M79A 1RA8A 3FQFA 2G6VA 1DDRA 3F0BX 4KJJA 4EILA 3RG9A 3F8YA 4LAHX 1S3YA 4PTHA 3JW3A 2LF1A 5DXVA 3K74A 4OSGA 4QLEA 4G95A 1VDRA 3CD2A 4M2XA 3NXRA 1DR1A 1DDSA 1TDRA 1LY4A 3JVXA 4KD7A 2BLBA 1DHFA 2W9GA 3INVA 5ECCA 4KFJA 3GYFA 2ITHA 1DYJA 4XECX 1KMVA 1DG5A 4H98A 1IA3A 3QL0A 4P3RA 3R33A 4M6JA 3TQAA 2W3VA 3GHVA 4Q0DA 3S9UA 1DRHA 4QJCA 3SGYA 3NZCX 4XRBA 1DR3A 3JSUA 4CD2A 4ELBA 1BZFA 3LG4A 1LUDA 3NXTA 1RA3A 1DHIA 2QK8A 2W3BA 3E0BA 2B3ZA 3OAFA 3FREX 5HQYA 3F91A 3D80A 4X5IA 4TU5X 5HQZA 2D0KA 5HT4A 1DF7A 3FY8X 3SR5X 1SEJA 4P66A 4X5FA 4XT6A 1DRAA 1AI9A 2W3WA 3IRNA 1RA1A 5U26A 1MVSA 1DRFA 3NTZA 1DR2A 3SAIA 2D5NA 4KYAA 4HA7A 4HOGA 1VJ3A 1DYIA 2HM9A 2L28A 1HFQA 3M09A 2HQPA 2W3AA 8DFRA 4KJLA 4EJ1A 4GH8A 3S7AA 1CZ3A 3F0QX 3TQBA 3DGAA 1D1GA 4QI9A 4KAKA 1DLSA 3FRBX 4XT5A 2GD9A 4FHBA 3M08A 1ZDRA 3ZPGA 3UM5A 2W9TA 3SA2A 3F8ZA 3ZPCA 1DG8A 3DATA 2JYBA 3SRRX 2W9HA 2H2QA 5ECXA 3FRFX 3SA1A 1OHKA 3QLRA 4LEKX 4Q6AA 3FRDX 1RH3A 5JG0X 5HPBA 3ROAA 4I13A 4KNEA 3QG2A 2FZIA 4PDJA 3FL9A 3GHCA 4DPDA 3L3RA 7DFRA 2O7PA 3QYOA 3NXVA 1RX6A 4NX7A 4EIGA 4P3QA 1MVTA 4I1NA 3RO9A 4ECKA 4Q67A 4QLGA 5JA3A 3QLZA 3FQZA 1E26A 1U72A
chains in the Genus database with same CATH topology
3FQ0A 4G8ZX 6DFRA 4KY4A 1KMSA 3NU0A 1QZFA 3QLYA 3IROA 1DR5A 3JWFA 3OCHA 2XW7A 3K45A 3CLBA 1M7AA 4PSTA 3CSEA 1S3UA 4HOEA 1RE7A 2W9SA 3NXOA 4DDRA 3SRSX 1DLRA 3FQVA 3FY9X 4XT7A 5HVBA 4DP3A 4OR7A 3FYVX 2P4GA 1HFRA 4P68A 3UM8A 3DG8A 3SH2A 1DAJA 4ELFA 1LY3A 4KBNA 3NZBX 2INQA 4EIZA 4RGCA 4LAGX 3KY8A 3F0XX 4KJKA 4XE6X 1JOLA 4M6LA 3I3RA 3FQCA 4XT4A 1J3KA 1CD2A 3JWKA 1DIUA 3EX8A 3DAUA 3NZ6X 3NZAX 4M7VA 3KGYA 3FQOA 3UM6A 4PSYA 3DRCA 1DR7A 5FDAA 1DHJA 2CD2A 3HBBA 3EIGA 3GHWA 1DISA 4KY8A 4X5HA 5CCCA 5U27A 4DFRA 1J3JA 3I8AX 3CL9A 3JTWA 4LAEX 3Q1HA 3KFYA 4KLXA 5E8QA 3VCOA 4KM0A 1DYRA 3JWCA 4HOFA 3NXYA 4H95A 5HUIA 3KJRA 1AOEA 3IX9A 3EEJA 1RB3A 2BLAA 1RX7A 1RG7A 1RF7A 1RX1A 1OHJA 1RC4A 2ZZAA 1RX2A 3JW5A 3KJSA 4M7UA 1BOZA 3NRRA 3SRWX 4HA9A 2KGKA 2W3MA 4IXGX 4M6KA 4DPHA 3IA5A 1J3IA 1DYHA 1JOMA 2ANOA 2CIGA 3NZDA 1RX8A 3QFXA 3FL8A 2FZHA 5HT5A 3F0SX 1RX5A 1DREA 3EEMA 3IRMA 4PTJA 3D84X 3SRUX 1AO8A 3F0UX 1HFPA 2C2SA 4H96A 1S3WA 4H97A 4X5GA 3TQ8A 4ELHA 4KL9A 5CC9A 5HVEA 5HI6A 3K2HA 1DR6A 1PD9A 4ELGA 2BL9A 5DFRA 4G3MA 3EELA 1YHOA 3DL6A 3EEKA 1M78A 4KEBA 2DHFA 3N0HA 1U70A 3QYLA 3TQ9A 4QLFA 4XT8A 5HSRA 4QJZD 3DFRA 2HXVA 3FS6A 3JWMA 4FGHA 1RA9A 2DRCA 2FZJA 4PSSA 1DR4A 3NZ9X 4KM2A 4Q0EA 3SQYX 1RX3A 3QL3A 5HSUA 2ANQA 4X5JA 3IA4A 4QHVA 1DG7A 4FGGA 1U71A 3SRQX 3QLWA 1IA4A 1PDBA 1RA2A 1RD7A 1JUVA 4NX6A 3FYWX 5EAJA 3QLXA 3FRAX 3GI2A 1IA1A 4IXFX 3S3VA 5HF2X 1PD8A 3QLSA 1RB2A 2OBCA 1RX4A 2BLCA 2C2TA 2AZNA 3DL5A 1RX9A 4ELEA 1IA2A 5HF0X 1S3VA 3NXXA 1KLKA 3TD8A 2OIPA 3K47A 1DRBA 3QGTA 3HJ3A 3F0VX 4IXED 1M79A 1RA8A 3FQFA 2G6VA 1DDRA 3F0BX 4KJJA 4EILA 3RG9A 3F8YA 4LAHX 1S3YA 4PTHA 3JW3A 2LF1A 5DXVA 3K74A 4OSGA 4QLEA 4G95A 1VDRA 3CD2A 4M2XA 3NXRA 1DR1A 1DDSA 1TDRA 1LY4A 3JVXA 4KD7A 2BLBA 1DHFA 2W9GA 3INVA 5ECCA 4KFJA 3GYFA 2ITHA 1DYJA 4XECX 1KMVA 1DG5A 4H98A 1IA3A 3QL0A 4P3RA 3R33A 4M6JA 3TQAA 2W3VA 3GHVA 4Q0DA 3S9UA 1DRHA 4QJCA 3SGYA 3NZCX 4XRBA 1DR3A 3JSUA 4CD2A 4ELBA 1BZFA 3LG4A 1LUDA 3NXTA 1RA3A 1DHIA 2QK8A 2W3BA 3E0BA 2B3ZA 3OAFA 3FREX 5HQYA 3F91A 3D80A 4X5IA 4TU5X 5HQZA 2D0KA 5HT4A 1DF7A 3FY8X 3SR5X 1SEJA 4P66A 4X5FA 4XT6A 1DRAA 1AI9A 2W3WA 3IRNA 1RA1A 5U26A 1MVSA 1DRFA 3NTZA 1DR2A 3SAIA 2D5NA 4KYAA 4HA7A 4HOGA 1VJ3A 1DYIA 2HM9A 2L28A 1HFQA 3M09A 2HQPA 2W3AA 8DFRA 4KJLA 4EJ1A 4GH8A 3S7AA 1CZ3A 3F0QX 3TQBA 3DGAA 1D1GA 4QI9A 4KAKA 1DLSA 3FRBX 4XT5A 2GD9A 4FHBA 3M08A 1ZDRA 3ZPGA 3UM5A 2W9TA 3SA2A 3F8ZA 3ZPCA 1DG8A 3DATA 2JYBA 3SRRX 2W9HA 2H2QA 5ECXA 3FRFX 3SA1A 1OHKA 3QLRA 4LEKX 4Q6AA 3FRDX 1RH3A 5JG0X 5HPBA 3ROAA 4I13A 4KNEA 3QG2A 2FZIA 4PDJA 3FL9A 3GHCA 4DPDA 3L3RA 7DFRA 2O7PA 3QYOA 3NXVA 1RX6A 4NX7A 4EIGA 4P3QA 1MVTA 4I1NA 3RO9A 4ECKA 4Q67A 4QLGA 5JA3A 3QLZA 3FQZA 1E26A 1U72A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FQ0 A;  4G8Z X;  6DFR A;  4KY4 A;  1KMS A;  3NU0 A;  1QZF A;  3QLY A;  3IRO A;  1DR5 A;  3JWF A;  3OCH A;  2XW7 A;  3K45 A;  3CLB A;  1M7A A;  4PST A;  3CSE A;  1S3U A;  4HOE A;  1RE7 A;  2W9S A;  3NXO A;  4DDR A;  3SRS X;  1DLR A;  3FQV A;  3FY9 X;  4XT7 A;  5HVB A;  4DP3 A;  4OR7 A;  3FYV X;  2P4G A;  1HFR A;  4P68 A;  3UM8 A;  3DG8 A;  3SH2 A;  1DAJ A;  4ELF A;  1LY3 A;  4KBN A;  3NZB X;  2INQ A;  4EIZ A;  4RGC A;  4LAG X;  3KY8 A;  3F0X X;  4KJK A;  4XE6 X;  1JOL A;  4M6L A;  3I3R A;  3FQC A;  4XT4 A;  1J3K A;  1CD2 A;  3JWK A;  1DIU A;  3EX8 A;  3DAU A;  3NZ6 X;  3NZA X;  4M7V A;  3KGY A;  3FQO A;  3UM6 A;  4PSY A;  3DRC A;  1DR7 A;  5FDA A;  1DHJ A;  2CD2 A;  3HBB A;  3EIG A;  3GHW A;  1DIS A;  4KY8 A;  4X5H A;  5CCC A;  5U27 A;  4DFR A;  1J3J A;  3I8A X;  3CL9 A;  3JTW A;  4LAE X;  3Q1H A;  3KFY A;  4KLX A;  5E8Q A;  3VCO A;  4KM0 A;  1DYR A;  3JWC A;  4HOF A;  3NXY A;  4H95 A;  5HUI A;  3KJR A;  1AOE A;  3IX9 A;  3EEJ A;  1RB3 A;  2BLA A;  1RX7 A;  1RG7 A;  1RF7 A;  1RX1 A;  1OHJ A;  1RC4 A;  2ZZA A;  1RX2 A;  3JW5 A;  3KJS A;  4M7U A;  1BOZ A;  3NRR A;  3SRW X;  4HA9 A;  2KGK A;  2W3M A;  4IXG X;  4M6K A;  4DPH A;  3IA5 A;  1J3I A;  1DYH A;  1JOM A;  2ANO A;  2CIG A;  3NZD A;  1RX8 A;  3QFX A;  3FL8 A;  2FZH A;  5HT5 A;  3F0S X;  1RX5 A;  1DRE A;  3EEM A;  3IRM A;  4PTJ A;  3D84 X;  3SRU X;  1AO8 A;  3F0U X;  1HFP A;  2C2S A;  4H96 A;  1S3W A;  4H97 A;  4X5G A;  3TQ8 A;  4ELH A;  4KL9 A;  5CC9 A;  5HVE A;  5HI6 A;  3K2H A;  1DR6 A;  1PD9 A;  4ELG A;  2BL9 A;  5DFR A;  4G3M A;  3EEL A;  1YHO A;  3DL6 A;  3EEK A;  1M78 A;  4KEB A;  2DHF A;  3N0H A;  1U70 A;  3QYL A;  3TQ9 A;  4QLF A;  4XT8 A;  5HSR A;  4QJZ D;  3DFR A;  2HXV A;  3FS6 A;  3JWM A;  4FGH A;  1RA9 A;  2DRC A;  2FZJ A;  4PSS A;  1DR4 A;  3NZ9 X;  4KM2 A;  4Q0E A;  3SQY X;  1RX3 A;  3QL3 A;  5HSU A;  2ANQ A;  4X5J A;  3IA4 A;  4QHV A;  1DG7 A;  4FGG A;  1U71 A;  3SRQ X;  3QLW A;  1IA4 A;  1PDB A;  1RA2 A;  1RD7 A;  1JUV A;  4NX6 A;  3FYW X;  5EAJ A;  3QLX A;  3FRA X;  3GI2 A;  1IA1 A;  4IXF X;  3S3V A;  5HF2 X;  1PD8 A;  3QLS A;  1RB2 A;  2OBC A;  1RX4 A;  2BLC A;  2C2T A;  2AZN A;  3DL5 A;  1RX9 A;  4ELE A;  1IA2 A;  5HF0 X;  1S3V A;  3NXX A;  1KLK A;  3TD8 A;  2OIP A;  3K47 A;  1DRB A;  3QGT A;  3HJ3 A;  3F0V X;  4IXE D;  1M79 A;  1RA8 A;  3FQF A;  2G6V A;  1DDR A;  3F0B X;  4KJJ A;  4EIL A;  3RG9 A;  3F8Y A;  4LAH X;  1S3Y A;  4PTH A;  3JW3 A;  2LF1 A;  5DXV A;  3K74 A;  4OSG A;  4QLE A;  4G95 A;  1VDR A;  3CD2 A;  4M2X A;  3NXR A;  1DR1 A;  1DDS A;  1TDR A;  1LY4 A;  3JVX A;  4KD7 A;  2BLB A;  1DHF A;  2W9G A;  3INV A;  5ECC A;  4KFJ A;  3GYF A;  2ITH A;  1DYJ A;  4XEC X;  1KMV A;  1DG5 A;  4H98 A;  1IA3 A;  3QL0 A;  4P3R A;  3R33 A;  4M6J A;  3TQA A;  2W3V A;  3GHV A;  4Q0D A;  3S9U A;  1DRH A;  4QJC A;  3SGY A;  3NZC X;  4XRB A;  1DR3 A;  3JSU A;  4CD2 A;  4ELB A;  1BZF A;  3LG4 A;  1LUD A;  3NXT A;  1RA3 A;  1DHI A;  2QK8 A;  2W3B A;  3E0B A;  2B3Z A;  3OAF A;  3FRE X;  5HQY A;  3F91 A;  3D80 A;  4X5I A;  4TU5 X;  5HQZ A;  2D0K A;  5HT4 A;  1DF7 A;  3FY8 X;  3SR5 X;  1SEJ A;  4P66 A;  4X5F A;  4XT6 A;  1DRA A;  1AI9 A;  2W3W A;  3IRN A;  1RA1 A;  5U26 A;  1MVS A;  1DRF A;  3NTZ A;  1DR2 A;  3SAI A;  2D5N A;  4KYA A;  4HA7 A;  4HOG A;  1VJ3 A;  1DYI A;  2HM9 A;  2L28 A;  1HFQ A;  3M09 A;  2HQP A;  2W3A A;  8DFR A;  4KJL A;  4EJ1 A;  4GH8 A;  3S7A A;  1CZ3 A;  3F0Q X;  3TQB A;  3DGA A;  1D1G A;  4QI9 A;  4KAK A;  1DLS A;  3FRB X;  4XT5 A;  2GD9 A;  4FHB A;  3M08 A;  1ZDR A;  3ZPG A;  3UM5 A;  2W9T A;  3SA2 A;  3F8Z A;  3ZPC A;  1DG8 A;  3DAT A;  2JYB A;  3SRR X;  2W9H A;  2H2Q A;  5ECX A;  3FRF X;  3SA1 A;  1OHK A;  3QLR A;  4LEK X;  4Q6A A;  3FRD X;  1RH3 A;  5JG0 X;  5HPB A;  3ROA A;  4I13 A;  4KNE A;  3QG2 A;  2FZI A;  4PDJ A;  3FL9 A;  3GHC A;  4DPD A;  3L3R A;  7DFR A;  2O7P A;  3QYO A;  3NXV A;  1RX6 A;  4NX7 A;  4EIG A;  4P3Q A;  1MVT A;  4I1N A;  3RO9 A;  4ECK A;  4Q67 A;  4QLG A;  5JA3 A;  3QLZ A;  3FQZ A;  1E26 A;  1U72 A; 
#chains in the Genus database with same CATH topology
 3FQ0 A;  4G8Z X;  6DFR A;  4KY4 A;  1KMS A;  3NU0 A;  1QZF A;  3QLY A;  3IRO A;  1DR5 A;  3JWF A;  3OCH A;  2XW7 A;  3K45 A;  3CLB A;  1M7A A;  4PST A;  3CSE A;  1S3U A;  4HOE A;  1RE7 A;  2W9S A;  3NXO A;  4DDR A;  3SRS X;  1DLR A;  3FQV A;  3FY9 X;  4XT7 A;  5HVB A;  4DP3 A;  4OR7 A;  3FYV X;  2P4G A;  1HFR A;  4P68 A;  3UM8 A;  3DG8 A;  3SH2 A;  1DAJ A;  4ELF A;  1LY3 A;  4KBN A;  3NZB X;  2INQ A;  4EIZ A;  4RGC A;  4LAG X;  3KY8 A;  3F0X X;  4KJK A;  4XE6 X;  1JOL A;  4M6L A;  3I3R A;  3FQC A;  4XT4 A;  1J3K A;  1CD2 A;  3JWK A;  1DIU A;  3EX8 A;  3DAU A;  3NZ6 X;  3NZA X;  4M7V A;  3KGY A;  3FQO A;  3UM6 A;  4PSY A;  3DRC A;  1DR7 A;  5FDA A;  1DHJ A;  2CD2 A;  3HBB A;  3EIG A;  3GHW A;  1DIS A;  4KY8 A;  4X5H A;  5CCC A;  5U27 A;  4DFR A;  1J3J A;  3I8A X;  3CL9 A;  3JTW A;  4LAE X;  3Q1H A;  3KFY A;  4KLX A;  5E8Q A;  3VCO A;  4KM0 A;  1DYR A;  3JWC A;  4HOF A;  3NXY A;  4H95 A;  5HUI A;  3KJR A;  1AOE A;  3IX9 A;  3EEJ A;  1RB3 A;  2BLA A;  1RX7 A;  1RG7 A;  1RF7 A;  1RX1 A;  1OHJ A;  1RC4 A;  2ZZA A;  1RX2 A;  3JW5 A;  3KJS A;  4M7U A;  1BOZ A;  3NRR A;  3SRW X;  4HA9 A;  2KGK A;  2W3M A;  4IXG X;  4M6K A;  4DPH A;  3IA5 A;  1J3I A;  1DYH A;  1JOM A;  2ANO A;  2CIG A;  3NZD A;  1RX8 A;  3QFX A;  3FL8 A;  2FZH A;  5HT5 A;  3F0S X;  1RX5 A;  1DRE A;  3EEM A;  3IRM A;  4PTJ A;  3D84 X;  3SRU X;  1AO8 A;  3F0U X;  1HFP A;  2C2S A;  4H96 A;  1S3W A;  4H97 A;  4X5G A;  3TQ8 A;  4ELH A;  4KL9 A;  5CC9 A;  5HVE A;  5HI6 A;  3K2H A;  1DR6 A;  1PD9 A;  4ELG A;  2BL9 A;  5DFR A;  4G3M A;  3EEL A;  1YHO A;  3DL6 A;  3EEK A;  1M78 A;  4KEB A;  2DHF A;  3N0H A;  1U70 A;  3QYL A;  3TQ9 A;  4QLF A;  4XT8 A;  5HSR A;  4QJZ D;  3DFR A;  2HXV A;  3FS6 A;  3JWM A;  4FGH A;  1RA9 A;  2DRC A;  2FZJ A;  4PSS A;  1DR4 A;  3NZ9 X;  4KM2 A;  4Q0E A;  3SQY X;  1RX3 A;  3QL3 A;  5HSU A;  2ANQ A;  4X5J A;  3IA4 A;  4QHV A;  1DG7 A;  4FGG A;  1U71 A;  3SRQ X;  3QLW A;  1IA4 A;  1PDB A;  1RA2 A;  1RD7 A;  1JUV A;  4NX6 A;  3FYW X;  5EAJ A;  3QLX A;  3FRA X;  3GI2 A;  1IA1 A;  4IXF X;  3S3V A;  5HF2 X;  1PD8 A;  3QLS A;  1RB2 A;  2OBC A;  1RX4 A;  2BLC A;  2C2T A;  2AZN A;  3DL5 A;  1RX9 A;  4ELE A;  1IA2 A;  5HF0 X;  1S3V A;  3NXX A;  1KLK A;  3TD8 A;  2OIP A;  3K47 A;  1DRB A;  3QGT A;  3HJ3 A;  3F0V X;  4IXE D;  1M79 A;  1RA8 A;  3FQF A;  2G6V A;  1DDR A;  3F0B X;  4KJJ A;  4EIL A;  3RG9 A;  3F8Y A;  4LAH X;  1S3Y A;  4PTH A;  3JW3 A;  2LF1 A;  5DXV A;  3K74 A;  4OSG A;  4QLE A;  4G95 A;  1VDR A;  3CD2 A;  4M2X A;  3NXR A;  1DR1 A;  1DDS A;  1TDR A;  1LY4 A;  3JVX A;  4KD7 A;  2BLB A;  1DHF A;  2W9G A;  3INV A;  5ECC A;  4KFJ A;  3GYF A;  2ITH A;  1DYJ A;  4XEC X;  1KMV A;  1DG5 A;  4H98 A;  1IA3 A;  3QL0 A;  4P3R A;  3R33 A;  4M6J A;  3TQA A;  2W3V A;  3GHV A;  4Q0D A;  3S9U A;  1DRH A;  4QJC A;  3SGY A;  3NZC X;  4XRB A;  1DR3 A;  3JSU A;  4CD2 A;  4ELB A;  1BZF A;  3LG4 A;  1LUD A;  3NXT A;  1RA3 A;  1DHI A;  2QK8 A;  2W3B A;  3E0B A;  2B3Z A;  3OAF A;  3FRE X;  5HQY A;  3F91 A;  3D80 A;  4X5I A;  4TU5 X;  5HQZ A;  2D0K A;  5HT4 A;  1DF7 A;  3FY8 X;  3SR5 X;  1SEJ A;  4P66 A;  4X5F A;  4XT6 A;  1DRA A;  1AI9 A;  2W3W A;  3IRN A;  1RA1 A;  5U26 A;  1MVS A;  1DRF A;  3NTZ A;  1DR2 A;  3SAI A;  2D5N A;  4KYA A;  4HA7 A;  4HOG A;  1VJ3 A;  1DYI A;  2HM9 A;  2L28 A;  1HFQ A;  3M09 A;  2HQP A;  2W3A A;  8DFR A;  4KJL A;  4EJ1 A;  4GH8 A;  3S7A A;  1CZ3 A;  3F0Q X;  3TQB A;  3DGA A;  1D1G A;  4QI9 A;  4KAK A;  1DLS A;  3FRB X;  4XT5 A;  2GD9 A;  4FHB A;  3M08 A;  1ZDR A;  3ZPG A;  3UM5 A;  2W9T A;  3SA2 A;  3F8Z A;  3ZPC A;  1DG8 A;  3DAT A;  2JYB A;  3SRR X;  2W9H A;  2H2Q A;  5ECX A;  3FRF X;  3SA1 A;  1OHK A;  3QLR A;  4LEK X;  4Q6A A;  3FRD X;  1RH3 A;  5JG0 X;  5HPB A;  3ROA A;  4I13 A;  4KNE A;  3QG2 A;  2FZI A;  4PDJ A;  3FL9 A;  3GHC A;  4DPD A;  3L3R A;  7DFR A;  2O7P A;  3QYO A;  3NXV A;  1RX6 A;  4NX7 A;  4EIG A;  4P3Q A;  1MVT A;  4I1N A;  3RO9 A;  4ECK A;  4Q67 A;  4QLG A;  5JA3 A;  3QLZ A;  3FQZ A;  1E26 A;  1U72 A; 
#chains in the Genus database with same CATH homology
 3FQ0 A;  4G8Z X;  6DFR A;  4KY4 A;  1KMS A;  3NU0 A;  1QZF A;  3QLY A;  3IRO A;  1DR5 A;  3JWF A;  3OCH A;  2XW7 A;  3K45 A;  3CLB A;  1M7A A;  4PST A;  3CSE A;  1S3U A;  4HOE A;  1RE7 A;  2W9S A;  3NXO A;  4DDR A;  3SRS X;  1DLR A;  3FQV A;  3FY9 X;  4XT7 A;  5HVB A;  4DP3 A;  4OR7 A;  3FYV X;  2P4G A;  1HFR A;  4P68 A;  3UM8 A;  3DG8 A;  3SH2 A;  1DAJ A;  4ELF A;  1LY3 A;  4KBN A;  3NZB X;  2INQ A;  4EIZ A;  4RGC A;  4LAG X;  3KY8 A;  3F0X X;  4KJK A;  4XE6 X;  1JOL A;  4M6L A;  3I3R A;  3FQC A;  4XT4 A;  1J3K A;  1CD2 A;  3JWK A;  1DIU A;  3EX8 A;  3DAU A;  3NZ6 X;  3NZA X;  4M7V A;  3KGY A;  3FQO A;  3UM6 A;  4PSY A;  3DRC A;  1DR7 A;  5FDA A;  1DHJ A;  2CD2 A;  3HBB A;  3EIG A;  3GHW A;  1DIS A;  4KY8 A;  4X5H A;  5CCC A;  5U27 A;  4DFR A;  1J3J A;  3I8A X;  3CL9 A;  3JTW A;  4LAE X;  3Q1H A;  3KFY A;  4KLX A;  5E8Q A;  3VCO A;  4KM0 A;  1DYR A;  3JWC A;  4HOF A;  3NXY A;  4H95 A;  5HUI A;  3KJR A;  1AOE A;  3IX9 A;  3EEJ A;  1RB3 A;  2BLA A;  1RX7 A;  1RG7 A;  1RF7 A;  1RX1 A;  1OHJ A;  1RC4 A;  2ZZA A;  1RX2 A;  3JW5 A;  3KJS A;  4M7U A;  1BOZ A;  3NRR A;  3SRW X;  4HA9 A;  2KGK A;  2W3M A;  4IXG X;  4M6K A;  4DPH A;  3IA5 A;  1J3I A;  1DYH A;  1JOM A;  2ANO A;  2CIG A;  3NZD A;  1RX8 A;  3QFX A;  3FL8 A;  2FZH A;  5HT5 A;  3F0S X;  1RX5 A;  1DRE A;  3EEM A;  3IRM A;  4PTJ A;  3D84 X;  3SRU X;  1AO8 A;  3F0U X;  1HFP A;  2C2S A;  4H96 A;  1S3W A;  4H97 A;  4X5G A;  3TQ8 A;  4ELH A;  4KL9 A;  5CC9 A;  5HVE A;  5HI6 A;  3K2H A;  1DR6 A;  1PD9 A;  4ELG A;  2BL9 A;  5DFR A;  4G3M A;  3EEL A;  1YHO A;  3DL6 A;  3EEK A;  1M78 A;  4KEB A;  2DHF A;  3N0H A;  1U70 A;  3QYL A;  3TQ9 A;  4QLF A;  4XT8 A;  5HSR A;  4QJZ D;  3DFR A;  2HXV A;  3FS6 A;  3JWM A;  4FGH A;  1RA9 A;  2DRC A;  2FZJ A;  4PSS A;  1DR4 A;  3NZ9 X;  4KM2 A;  4Q0E A;  3SQY X;  1RX3 A;  3QL3 A;  5HSU A;  2ANQ A;  4X5J A;  3IA4 A;  4QHV A;  1DG7 A;  4FGG A;  1U71 A;  3SRQ X;  3QLW A;  1IA4 A;  1PDB A;  1RA2 A;  1RD7 A;  1JUV A;  4NX6 A;  3FYW X;  5EAJ A;  3QLX A;  3FRA X;  3GI2 A;  1IA1 A;  4IXF X;  3S3V A;  5HF2 X;  1PD8 A;  3QLS A;  1RB2 A;  2OBC A;  1RX4 A;  2BLC A;  2C2T A;  2AZN A;  3DL5 A;  1RX9 A;  4ELE A;  1IA2 A;  5HF0 X;  1S3V A;  3NXX A;  1KLK A;  3TD8 A;  2OIP A;  3K47 A;  1DRB A;  3QGT A;  3HJ3 A;  3F0V X;  4IXE D;  1M79 A;  1RA8 A;  3FQF A;  2G6V A;  1DDR A;  3F0B X;  4KJJ A;  4EIL A;  3RG9 A;  3F8Y A;  4LAH X;  1S3Y A;  4PTH A;  3JW3 A;  2LF1 A;  5DXV A;  3K74 A;  4OSG A;  4QLE A;  4G95 A;  1VDR A;  3CD2 A;  4M2X A;  3NXR A;  1DR1 A;  1DDS A;  1TDR A;  1LY4 A;  3JVX A;  4KD7 A;  2BLB A;  1DHF A;  2W9G A;  3INV A;  5ECC A;  4KFJ A;  3GYF A;  2ITH A;  1DYJ A;  4XEC X;  1KMV A;  1DG5 A;  4H98 A;  1IA3 A;  3QL0 A;  4P3R A;  3R33 A;  4M6J A;  3TQA A;  2W3V A;  3GHV A;  4Q0D A;  3S9U A;  1DRH A;  4QJC A;  3SGY A;  3NZC X;  4XRB A;  1DR3 A;  3JSU A;  4CD2 A;  4ELB A;  1BZF A;  3LG4 A;  1LUD A;  3NXT A;  1RA3 A;  1DHI A;  2QK8 A;  2W3B A;  3E0B A;  2B3Z A;  3OAF A;  3FRE X;  5HQY A;  3F91 A;  3D80 A;  4X5I A;  4TU5 X;  5HQZ A;  2D0K A;  5HT4 A;  1DF7 A;  3FY8 X;  3SR5 X;  1SEJ A;  4P66 A;  4X5F A;  4XT6 A;  1DRA A;  1AI9 A;  2W3W A;  3IRN A;  1RA1 A;  5U26 A;  1MVS A;  1DRF A;  3NTZ A;  1DR2 A;  3SAI A;  2D5N A;  4KYA A;  4HA7 A;  4HOG A;  1VJ3 A;  1DYI A;  2HM9 A;  2L28 A;  1HFQ A;  3M09 A;  2HQP A;  2W3A A;  8DFR A;  4KJL A;  4EJ1 A;  4GH8 A;  3S7A A;  1CZ3 A;  3F0Q X;  3TQB A;  3DGA A;  1D1G A;  4QI9 A;  4KAK A;  1DLS A;  3FRB X;  4XT5 A;  2GD9 A;  4FHB A;  3M08 A;  1ZDR A;  3ZPG A;  3UM5 A;  2W9T A;  3SA2 A;  3F8Z A;  3ZPC A;  1DG8 A;  3DAT A;  2JYB A;  3SRR X;  2W9H A;  2H2Q A;  5ECX A;  3FRF X;  3SA1 A;  1OHK A;  3QLR A;  4LEK X;  4Q6A A;  3FRD X;  1RH3 A;  5JG0 X;  5HPB A;  3ROA A;  4I13 A;  4KNE A;  3QG2 A;  2FZI A;  4PDJ A;  3FL9 A;  3GHC A;  4DPD A;  3L3R A;  7DFR A;  2O7P A;  3QYO A;  3NXV A;  1RX6 A;  4NX7 A;  4EIG A;  4P3Q A;  1MVT A;  4I1N A;  3RO9 A;  4ECK A;  4Q67 A;  4QLG A;  5JA3 A;  3QLZ A;  3FQZ A;  1E26 A;  1U72 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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