3EEMA

Candida glabrata dihydrofolate reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)prop-1-ynyl]-6-methylpyrimidine(ucp111d26m) and nadph
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
225
structure length
225
Chain Sequence
KVPVVGIVAALLPEMGIGFQGNLPWRLAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQKFRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGEIYRQSMDLADHWLITKIMPLPETTIPQMDTFLQKQELEQRFYDNSDKLVDFLPSSIQLEGRLTSQEWNGELVKGLPVQEKGYQFYFTLYTKKLEHHHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Candida glabrata
molecule keywords Dihydrofolate reductase
total genus 60
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3eemA00
1RX1A 5HF0X 3KY8A 4KBNA 1HFRA 3K2HA 3FRAX 1HFPA 1BZFA 1DDRA 2CD2A 1JUVA 1DLRA 4P66A 2GD9A 1PD8A 3QYLA 3QLYA 4G8ZX 4G95A 8DFRA 4M7UA 4KD7A 4H95A 4HOEA 4OSGA 3K45A 3DATA 1SEJA 3NU0A 4ELGA 5HT5A 3TQBA 1S3YA 1DYIA 4H97A 1RA2A 3ROAA 3IA4A 1U71A 4LAGX 1KMSA 1PDBA 4Q0DA 5ECXA 4KJLA 5HQZA 2W3AA 2B3ZA 2HXVA 3FS6A 4QJZD 3SRWX 3QLWA 3NZAX 4H96A 4FGHA 3M08A 2G6VA 3NXVA 3GYFA 3NXRA 3NTZA 1KMVA 3FQCA 2ANOA 3HJ3A 1M79A 4IXFX 4X5FA 2C2SA 1DG8A 1DF7A 1DRAA 4DP3A 3QG2A 1RX2A 3JTWA 4XT4A 3CD2A 2W9GA 1JOMA 2W3MA 3QLZA 5HUIA 4EIZA 4PTJA 3K74A 3NXTA 1VDRA 1PD9A 1QZFA 4NX6A 4XT5A 3R33A 1DREA 1MVSA 5CCCA 4HOGA 1E26A 3IRNA 4KJJA 4OR7A 2D5NA 1S3VA 3GHCA 5CC9A 1DIUA 4FHBA 3F91A 3KFYA 1U72A 3QL0A 1RX5A 4M7VA 3TQ9A 1DHFA 1DG5A 1DR1A 3DRCA 1CD2A 3QFXA 3JW3A 5U27A 3EEMA 1RD7A 3KJSA 3I3RA 3NXOA 4QI9A 1VJ3A 3EEJA 3FYVX 3JWCA 1IA4A 1LY4A 4I13A 5DXVA 2C2TA 4ELHA 3CL9A 4XRBA 1RX9A 2DHFA 1DR5A 3SRQX 1RH3A 3D84X 3NZ9X 2FZIA 3TQ8A 1DYHA 3QL3A 4X5IA 3S3VA 3KGYA 3CLBA 3ZPCA 3RO9A 3IROA 4M6JA 1U70A 3Q1HA 3L3RA 5E8QA 2ZZAA 2FZJA 4XECX 4ECKA 1ZDRA 3SH2A 1S3WA 3F0QX 1DHIA 2HM9A 3FY9X 2INQA 3QLRA 4PTHA 3EIGA 1RF7A 3F0BX 4ELFA 1DR4A 1AO8A 4KLXA 4KM2A 1DR7A 4KY8A 1RA1A 4X5GA 1YHOA 4P3QA 1J3KA 2AZNA 4ELBA 3JWMA 4ELEA 3UM5A 3UM8A 3NZ6X 3F8ZA 3FL8A 4KAKA 3DGAA 5HSRA 4DDRA 3FRFX 2W3WA 3LG4A 5HF2X 1TDRA 1OHKA 3VCOA 1DISA 5HPBA 3DAUA 3FQVA 2BLAA 1DRHA 4XT6A 1JOLA 2W9SA 1J3IA 2KGKA 4LEKX 3F0XX 3OCHA 1D1GA 5U26A 4IXED 4I1NA 4KY4A 3FQZA 5HVEA 5ECCA 1DR3A 3DL5A 3FQOA 3FRDX 4PSSA 2LF1A 3F0UX 1S3UA 4XE6X 3F0VX 4EJ1A 4KM0A 4M2XA 1RX6A 3INVA 5EAJA 4EILA 4GH8A 3FRBX 1LY3A 1OHJA 4DPHA 3UM6A 3QGTA 3CSEA 3SRSX 3FREX 2O7PA 2DRCA 3F0SX 3NXXA 1LUDA 1IA3A 3FYWX 5HI6A 4HA9A 3ZPGA 1RA8A 3EEKA 5HSUA 3GI2A 3F8YA 2OBCA 3FQFA 1MVTA 3IA5A 2BLBA 4CD2A 3N0HA 3JW5A 4KFJA 3KJRA 4P68A 1DLSA 3JVXA 3NZDA 3EX8A 3SAIA 3SRRX 2BLCA 3JSUA 1DR6A 4DPDA 3S7AA 1M78A 1RX7A 4QLEA 1RC4A 3NZCX 4QLGA 1DYJA 1DAJA 3TQAA 2H2QA 4IXGX 3TD8A 4HOFA 3SQYX 3DL6A 3S9UA 4QHVA 3HBBA 4TU5X 1IA1A 3DG8A 3IRMA 4PSTA 1AI9A 4P3RA 1DHJA 1RX3A 4KL9A 4KEBA 1RA3A 1DDSA 3NZBX 1RX4A 4QLFA 3NXYA 5JA3A 4Q6AA 2W3VA 4M6LA 3JWFA 3D80A 1RX8A 3OAFA 4M6KA 3FL9A 4LAEX 3EELA 4X5JA 1DRFA 1AOEA 2W9TA 1RB2A 3QYOA 2CIGA 3FQ0A 2FZHA 1RA9A 3SR5X 5HT4A 2XW7A 1KLKA 3GHWA 4FGGA 4PSYA 2BL9A 3QLXA 4DFRA 3SA1A 2ANQA 3JWKA 4PDJA 2P4GA 1BOZA 1CZ3A 1IA2A 4Q0EA 5DFRA 1RG7A 4HA7A 3IX9A 4XT7A 1DG7A 4RGCA 1DRBA 3SA2A 4H98A 5FDAA 3DFRA 4KJKA 3K47A 3GHVA 2W9HA 1RE7A 1DYRA 3E0BA 1RB3A 5JG0X 2ITHA 6DFRA 3M09A 3SRUX 4XT8A 3NRRA 1M7AA 4QJCA 4LAHX 4EIGA 5HVBA 3I8AX 4X5HA 3SGYA 2JYBA 4G3MA 1J3JA 2D0KA 1DR2A 2W3BA 1HFQA 3RG9A 3FY8X 2HQPA 7DFRA 2OIPA 4Q67A 2QK8A 4KYAA 2L28A 5HQYA 4NX7A 3QLSA 4KNEA
chains in the Genus database with same CATH superfamily
1RX1A 5HF0X 3KY8A 4KBNA 1HFRA 3K2HA 3FRAX 1HFPA 1BZFA 1DDRA 2CD2A 1JUVA 1DLRA 4P66A 2GD9A 1PD8A 3QYLA 3QLYA 4G8ZX 4G95A 8DFRA 4M7UA 4KD7A 4H95A 4HOEA 4OSGA 3K45A 3DATA 1SEJA 3NU0A 4ELGA 5HT5A 3TQBA 1S3YA 1DYIA 4H97A 1RA2A 3ROAA 3IA4A 1U71A 4LAGX 1KMSA 1PDBA 4Q0DA 5ECXA 4KJLA 5HQZA 2W3AA 2B3ZA 2HXVA 3FS6A 4QJZD 3SRWX 3QLWA 3NZAX 4H96A 4FGHA 3M08A 2G6VA 3NXVA 3GYFA 3NXRA 3NTZA 1KMVA 3FQCA 2ANOA 3HJ3A 1M79A 4IXFX 4X5FA 2C2SA 1DG8A 1DF7A 1DRAA 4DP3A 3QG2A 1RX2A 3JTWA 4XT4A 3CD2A 2W9GA 1JOMA 2W3MA 3QLZA 5HUIA 4EIZA 4PTJA 3K74A 3NXTA 1VDRA 1PD9A 1QZFA 4NX6A 4XT5A 3R33A 1DREA 1MVSA 5CCCA 4HOGA 1E26A 3IRNA 4KJJA 4OR7A 2D5NA 1S3VA 3GHCA 5CC9A 1DIUA 4FHBA 3F91A 3KFYA 1U72A 3QL0A 1RX5A 4M7VA 3TQ9A 1DHFA 1DG5A 1DR1A 3DRCA 1CD2A 3QFXA 3JW3A 5U27A 3EEMA 1RD7A 3KJSA 3I3RA 3NXOA 4QI9A 1VJ3A 3EEJA 3FYVX 3JWCA 1IA4A 1LY4A 4I13A 5DXVA 2C2TA 4ELHA 3CL9A 4XRBA 1RX9A 2DHFA 1DR5A 3SRQX 1RH3A 3D84X 3NZ9X 2FZIA 3TQ8A 1DYHA 3QL3A 4X5IA 3S3VA 3KGYA 3CLBA 3ZPCA 3RO9A 3IROA 4M6JA 1U70A 3Q1HA 3L3RA 5E8QA 2ZZAA 2FZJA 4XECX 4ECKA 1ZDRA 3SH2A 1S3WA 3F0QX 1DHIA 2HM9A 3FY9X 2INQA 3QLRA 4PTHA 3EIGA 1RF7A 3F0BX 4ELFA 1DR4A 1AO8A 4KLXA 4KM2A 1DR7A 4KY8A 1RA1A 4X5GA 1YHOA 4P3QA 1J3KA 2AZNA 4ELBA 3JWMA 4ELEA 3UM5A 3UM8A 3NZ6X 3F8ZA 3FL8A 4KAKA 3DGAA 5HSRA 4DDRA 3FRFX 2W3WA 3LG4A 5HF2X 1TDRA 1OHKA 3VCOA 1DISA 5HPBA 3DAUA 3FQVA 2BLAA 1DRHA 4XT6A 1JOLA 2W9SA 1J3IA 2KGKA 4LEKX 3F0XX 3OCHA 1D1GA 5U26A 4IXED 4I1NA 4KY4A 3FQZA 5HVEA 5ECCA 1DR3A 3DL5A 3FQOA 3FRDX 4PSSA 2LF1A 3F0UX 1S3UA 4XE6X 3F0VX 4EJ1A 4KM0A 4M2XA 1RX6A 3INVA 5EAJA 4EILA 4GH8A 3FRBX 1LY3A 1OHJA 4DPHA 3UM6A 3QGTA 3CSEA 3SRSX 3FREX 2O7PA 2DRCA 3F0SX 3NXXA 1LUDA 1IA3A 3FYWX 5HI6A 4HA9A 3ZPGA 1RA8A 3EEKA 5HSUA 3GI2A 3F8YA 2OBCA 3FQFA 1MVTA 3IA5A 2BLBA 4CD2A 3N0HA 3JW5A 4KFJA 3KJRA 4P68A 1DLSA 3JVXA 3NZDA 3EX8A 3SAIA 3SRRX 2BLCA 3JSUA 1DR6A 4DPDA 3S7AA 1M78A 1RX7A 4QLEA 1RC4A 3NZCX 4QLGA 1DYJA 1DAJA 3TQAA 2H2QA 4IXGX 3TD8A 4HOFA 3SQYX 3DL6A 3S9UA 4QHVA 3HBBA 4TU5X 1IA1A 3DG8A 3IRMA 4PSTA 1AI9A 4P3RA 1DHJA 1RX3A 4KL9A 4KEBA 1RA3A 1DDSA 3NZBX 1RX4A 4QLFA 3NXYA 5JA3A 4Q6AA 2W3VA 4M6LA 3JWFA 3D80A 1RX8A 3OAFA 4M6KA 3FL9A 4LAEX 3EELA 4X5JA 1DRFA 1AOEA 2W9TA 1RB2A 3QYOA 2CIGA 3FQ0A 2FZHA 1RA9A 3SR5X 5HT4A 2XW7A 1KLKA 3GHWA 4FGGA 4PSYA 2BL9A 3QLXA 4DFRA 3SA1A 2ANQA 3JWKA 4PDJA 2P4GA 1BOZA 1CZ3A 1IA2A 4Q0EA 5DFRA 1RG7A 4HA7A 3IX9A 4XT7A 1DG7A 4RGCA 1DRBA 3SA2A 4H98A 5FDAA 3DFRA 4KJKA 3K47A 3GHVA 2W9HA 1RE7A 1DYRA 3E0BA 1RB3A 5JG0X 2ITHA 6DFRA 3M09A 3SRUX 4XT8A 3NRRA 1M7AA 4QJCA 4LAHX 4EIGA 5HVBA 3I8AX 4X5HA 3SGYA 2JYBA 4G3MA 1J3JA 2D0KA 1DR2A 2W3BA 1HFQA 3RG9A 3FY8X 2HQPA 7DFRA 2OIPA 4Q67A 2QK8A 4KYAA 2L28A 5HQYA 4NX7A 3QLSA 4KNEA
chains in the Genus database with same CATH topology
1RX1A 5HF0X 3KY8A 4KBNA 1HFRA 3K2HA 3FRAX 1HFPA 1BZFA 1DDRA 2CD2A 1JUVA 1DLRA 4P66A 2GD9A 1PD8A 3QYLA 3QLYA 4G8ZX 4G95A 8DFRA 4M7UA 4KD7A 4H95A 4HOEA 4OSGA 3K45A 3DATA 1SEJA 3NU0A 4ELGA 5HT5A 3TQBA 1S3YA 1DYIA 4H97A 1RA2A 3ROAA 3IA4A 1U71A 4LAGX 1KMSA 1PDBA 4Q0DA 5ECXA 4KJLA 5HQZA 2W3AA 2B3ZA 2HXVA 3FS6A 4QJZD 3SRWX 3QLWA 3NZAX 4H96A 4FGHA 3M08A 2G6VA 3NXVA 3GYFA 3NXRA 3NTZA 1KMVA 3FQCA 2ANOA 3HJ3A 1M79A 4IXFX 4X5FA 2C2SA 1DG8A 1DF7A 1DRAA 4DP3A 3QG2A 1RX2A 3JTWA 4XT4A 3CD2A 2W9GA 1JOMA 2W3MA 3QLZA 5HUIA 4EIZA 4PTJA 3K74A 3NXTA 1VDRA 1PD9A 1QZFA 4NX6A 4XT5A 3R33A 1DREA 1MVSA 5CCCA 4HOGA 1E26A 3IRNA 4KJJA 4OR7A 2D5NA 1S3VA 3GHCA 5CC9A 1DIUA 4FHBA 3F91A 3KFYA 1U72A 3QL0A 1RX5A 4M7VA 3TQ9A 1DHFA 1DG5A 1DR1A 3DRCA 1CD2A 3QFXA 3JW3A 5U27A 3EEMA 1RD7A 3KJSA 3I3RA 3NXOA 4QI9A 1VJ3A 3EEJA 3FYVX 3JWCA 1IA4A 1LY4A 4I13A 5DXVA 2C2TA 4ELHA 3CL9A 4XRBA 1RX9A 2DHFA 1DR5A 3SRQX 1RH3A 3D84X 3NZ9X 2FZIA 3TQ8A 1DYHA 3QL3A 4X5IA 3S3VA 3KGYA 3CLBA 3ZPCA 3RO9A 3IROA 4M6JA 1U70A 3Q1HA 3L3RA 5E8QA 2ZZAA 2FZJA 4XECX 4ECKA 1ZDRA 3SH2A 1S3WA 3F0QX 1DHIA 2HM9A 3FY9X 2INQA 3QLRA 4PTHA 3EIGA 1RF7A 3F0BX 4ELFA 1DR4A 1AO8A 4KLXA 4KM2A 1DR7A 4KY8A 1RA1A 4X5GA 1YHOA 4P3QA 1J3KA 2AZNA 4ELBA 3JWMA 4ELEA 3UM5A 3UM8A 3NZ6X 3F8ZA 3FL8A 4KAKA 3DGAA 5HSRA 4DDRA 3FRFX 2W3WA 3LG4A 5HF2X 1TDRA 1OHKA 3VCOA 1DISA 5HPBA 3DAUA 3FQVA 2BLAA 1DRHA 4XT6A 1JOLA 2W9SA 1J3IA 2KGKA 4LEKX 3F0XX 3OCHA 1D1GA 5U26A 4IXED 4I1NA 4KY4A 3FQZA 5HVEA 5ECCA 1DR3A 3DL5A 3FQOA 3FRDX 4PSSA 2LF1A 3F0UX 1S3UA 4XE6X 3F0VX 4EJ1A 4KM0A 4M2XA 1RX6A 3INVA 5EAJA 4EILA 4GH8A 3FRBX 1LY3A 1OHJA 4DPHA 3UM6A 3QGTA 3CSEA 3SRSX 3FREX 2O7PA 2DRCA 3F0SX 3NXXA 1LUDA 1IA3A 3FYWX 5HI6A 4HA9A 3ZPGA 1RA8A 3EEKA 5HSUA 3GI2A 3F8YA 2OBCA 3FQFA 1MVTA 3IA5A 2BLBA 4CD2A 3N0HA 3JW5A 4KFJA 3KJRA 4P68A 1DLSA 3JVXA 3NZDA 3EX8A 3SAIA 3SRRX 2BLCA 3JSUA 1DR6A 4DPDA 3S7AA 1M78A 1RX7A 4QLEA 1RC4A 3NZCX 4QLGA 1DYJA 1DAJA 3TQAA 2H2QA 4IXGX 3TD8A 4HOFA 3SQYX 3DL6A 3S9UA 4QHVA 3HBBA 4TU5X 1IA1A 3DG8A 3IRMA 4PSTA 1AI9A 4P3RA 1DHJA 1RX3A 4KL9A 4KEBA 1RA3A 1DDSA 3NZBX 1RX4A 4QLFA 3NXYA 5JA3A 4Q6AA 2W3VA 4M6LA 3JWFA 3D80A 1RX8A 3OAFA 4M6KA 3FL9A 4LAEX 3EELA 4X5JA 1DRFA 1AOEA 2W9TA 1RB2A 3QYOA 2CIGA 3FQ0A 2FZHA 1RA9A 3SR5X 5HT4A 2XW7A 1KLKA 3GHWA 4FGGA 4PSYA 2BL9A 3QLXA 4DFRA 3SA1A 2ANQA 3JWKA 4PDJA 2P4GA 1BOZA 1CZ3A 1IA2A 4Q0EA 5DFRA 1RG7A 4HA7A 3IX9A 4XT7A 1DG7A 4RGCA 1DRBA 3SA2A 4H98A 5FDAA 3DFRA 4KJKA 3K47A 3GHVA 2W9HA 1RE7A 1DYRA 3E0BA 1RB3A 5JG0X 2ITHA 6DFRA 3M09A 3SRUX 4XT8A 3NRRA 1M7AA 4QJCA 4LAHX 4EIGA 5HVBA 3I8AX 4X5HA 3SGYA 2JYBA 4G3MA 1J3JA 2D0KA 1DR2A 2W3BA 1HFQA 3RG9A 3FY8X 2HQPA 7DFRA 2OIPA 4Q67A 2QK8A 4KYAA 2L28A 5HQYA 4NX7A 3QLSA 4KNEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RX1 A;  5HF0 X;  3KY8 A;  4KBN A;  1HFR A;  3K2H A;  3FRA X;  1HFP A;  1BZF A;  1DDR A;  2CD2 A;  1JUV A;  1DLR A;  4P66 A;  2GD9 A;  1PD8 A;  3QYL A;  3QLY A;  4G8Z X;  4G95 A;  8DFR A;  4M7U A;  4KD7 A;  4H95 A;  4HOE A;  4OSG A;  3K45 A;  3DAT A;  1SEJ A;  3NU0 A;  4ELG A;  5HT5 A;  3TQB A;  1S3Y A;  1DYI A;  4H97 A;  1RA2 A;  3ROA A;  3IA4 A;  1U71 A;  4LAG X;  1KMS A;  1PDB A;  4Q0D A;  5ECX A;  4KJL A;  5HQZ A;  2W3A A;  2B3Z A;  2HXV A;  3FS6 A;  4QJZ D;  3SRW X;  3QLW A;  3NZA X;  4H96 A;  4FGH A;  3M08 A;  2G6V A;  3NXV A;  3GYF A;  3NXR A;  3NTZ A;  1KMV A;  3FQC A;  2ANO A;  3HJ3 A;  1M79 A;  4IXF X;  4X5F A;  2C2S A;  1DG8 A;  1DF7 A;  1DRA A;  4DP3 A;  3QG2 A;  1RX2 A;  3JTW A;  4XT4 A;  3CD2 A;  2W9G A;  1JOM A;  2W3M A;  3QLZ A;  5HUI A;  4EIZ A;  4PTJ A;  3K74 A;  3NXT A;  1VDR A;  1PD9 A;  1QZF A;  4NX6 A;  4XT5 A;  3R33 A;  1DRE A;  1MVS A;  5CCC A;  4HOG A;  1E26 A;  3IRN A;  4KJJ A;  4OR7 A;  2D5N A;  1S3V A;  3GHC A;  5CC9 A;  1DIU A;  4FHB A;  3F91 A;  3KFY A;  1U72 A;  3QL0 A;  1RX5 A;  4M7V A;  3TQ9 A;  1DHF A;  1DG5 A;  1DR1 A;  3DRC A;  1CD2 A;  3QFX A;  3JW3 A;  5U27 A;  3EEM A;  1RD7 A;  3KJS A;  3I3R A;  3NXO A;  4QI9 A;  1VJ3 A;  3EEJ A;  3FYV X;  3JWC A;  1IA4 A;  1LY4 A;  4I13 A;  5DXV A;  2C2T A;  4ELH A;  3CL9 A;  4XRB A;  1RX9 A;  2DHF A;  1DR5 A;  3SRQ X;  1RH3 A;  3D84 X;  3NZ9 X;  2FZI A;  3TQ8 A;  1DYH A;  3QL3 A;  4X5I A;  3S3V A;  3KGY A;  3CLB A;  3ZPC A;  3RO9 A;  3IRO A;  4M6J A;  1U70 A;  3Q1H A;  3L3R A;  5E8Q A;  2ZZA A;  2FZJ A;  4XEC X;  4ECK A;  1ZDR A;  3SH2 A;  1S3W A;  3F0Q X;  1DHI A;  2HM9 A;  3FY9 X;  2INQ A;  3QLR A;  4PTH A;  3EIG A;  1RF7 A;  3F0B X;  4ELF A;  1DR4 A;  1AO8 A;  4KLX A;  4KM2 A;  1DR7 A;  4KY8 A;  1RA1 A;  4X5G A;  1YHO A;  4P3Q A;  1J3K A;  2AZN A;  4ELB A;  3JWM A;  4ELE A;  3UM5 A;  3UM8 A;  3NZ6 X;  3F8Z A;  3FL8 A;  4KAK A;  3DGA A;  5HSR A;  4DDR A;  3FRF X;  2W3W A;  3LG4 A;  5HF2 X;  1TDR A;  1OHK A;  3VCO A;  1DIS A;  5HPB A;  3DAU A;  3FQV A;  2BLA A;  1DRH A;  4XT6 A;  1JOL A;  2W9S A;  1J3I A;  2KGK A;  4LEK X;  3F0X X;  3OCH A;  1D1G A;  5U26 A;  4IXE D;  4I1N A;  4KY4 A;  3FQZ A;  5HVE A;  5ECC A;  1DR3 A;  3DL5 A;  3FQO A;  3FRD X;  4PSS A;  2LF1 A;  3F0U X;  1S3U A;  4XE6 X;  3F0V X;  4EJ1 A;  4KM0 A;  4M2X A;  1RX6 A;  3INV A;  5EAJ A;  4EIL A;  4GH8 A;  3FRB X;  1LY3 A;  1OHJ A;  4DPH A;  3UM6 A;  3QGT A;  3CSE A;  3SRS X;  3FRE X;  2O7P A;  2DRC A;  3F0S X;  3NXX A;  1LUD A;  1IA3 A;  3FYW X;  5HI6 A;  4HA9 A;  3ZPG A;  1RA8 A;  3EEK A;  5HSU A;  3GI2 A;  3F8Y A;  2OBC A;  3FQF A;  1MVT A;  3IA5 A;  2BLB A;  4CD2 A;  3N0H A;  3JW5 A;  4KFJ A;  3KJR A;  4P68 A;  1DLS A;  3JVX A;  3NZD A;  3EX8 A;  3SAI A;  3SRR X;  2BLC A;  3JSU A;  1DR6 A;  4DPD A;  3S7A A;  1M78 A;  1RX7 A;  4QLE A;  1RC4 A;  3NZC X;  4QLG A;  1DYJ A;  1DAJ A;  3TQA A;  2H2Q A;  4IXG X;  3TD8 A;  4HOF A;  3SQY X;  3DL6 A;  3S9U A;  4QHV A;  3HBB A;  4TU5 X;  1IA1 A;  3DG8 A;  3IRM A;  4PST A;  1AI9 A;  4P3R A;  1DHJ A;  1RX3 A;  4KL9 A;  4KEB A;  1RA3 A;  1DDS A;  3NZB X;  1RX4 A;  4QLF A;  3NXY A;  5JA3 A;  4Q6A A;  2W3V A;  4M6L A;  3JWF A;  3D80 A;  1RX8 A;  3OAF A;  4M6K A;  3FL9 A;  4LAE X;  3EEL A;  4X5J A;  1DRF A;  1AOE A;  2W9T A;  1RB2 A;  3QYO A;  2CIG A;  3FQ0 A;  2FZH A;  1RA9 A;  3SR5 X;  5HT4 A;  2XW7 A;  1KLK A;  3GHW A;  4FGG A;  4PSY A;  2BL9 A;  3QLX A;  4DFR A;  3SA1 A;  2ANQ A;  3JWK A;  4PDJ A;  2P4G A;  1BOZ A;  1CZ3 A;  1IA2 A;  4Q0E A;  5DFR A;  1RG7 A;  4HA7 A;  3IX9 A;  4XT7 A;  1DG7 A;  4RGC A;  1DRB A;  3SA2 A;  4H98 A;  5FDA A;  3DFR A;  4KJK A;  3K47 A;  3GHV A;  2W9H A;  1RE7 A;  1DYR A;  3E0B A;  1RB3 A;  5JG0 X;  2ITH A;  6DFR A;  3M09 A;  3SRU X;  4XT8 A;  3NRR A;  1M7A A;  4QJC A;  4LAH X;  4EIG A;  5HVB A;  3I8A X;  4X5H A;  3SGY A;  2JYB A;  4G3M A;  1J3J A;  2D0K A;  1DR2 A;  2W3B A;  1HFQ A;  3RG9 A;  3FY8 X;  2HQP A;  7DFR A;  2OIP A;  4Q67 A;  2QK8 A;  4KYA A;  2L28 A;  5HQY A;  4NX7 A;  3QLS A;  4KNE A; 
#chains in the Genus database with same CATH topology
 1RX1 A;  5HF0 X;  3KY8 A;  4KBN A;  1HFR A;  3K2H A;  3FRA X;  1HFP A;  1BZF A;  1DDR A;  2CD2 A;  1JUV A;  1DLR A;  4P66 A;  2GD9 A;  1PD8 A;  3QYL A;  3QLY A;  4G8Z X;  4G95 A;  8DFR A;  4M7U A;  4KD7 A;  4H95 A;  4HOE A;  4OSG A;  3K45 A;  3DAT A;  1SEJ A;  3NU0 A;  4ELG A;  5HT5 A;  3TQB A;  1S3Y A;  1DYI A;  4H97 A;  1RA2 A;  3ROA A;  3IA4 A;  1U71 A;  4LAG X;  1KMS A;  1PDB A;  4Q0D A;  5ECX A;  4KJL A;  5HQZ A;  2W3A A;  2B3Z A;  2HXV A;  3FS6 A;  4QJZ D;  3SRW X;  3QLW A;  3NZA X;  4H96 A;  4FGH A;  3M08 A;  2G6V A;  3NXV A;  3GYF A;  3NXR A;  3NTZ A;  1KMV A;  3FQC A;  2ANO A;  3HJ3 A;  1M79 A;  4IXF X;  4X5F A;  2C2S A;  1DG8 A;  1DF7 A;  1DRA A;  4DP3 A;  3QG2 A;  1RX2 A;  3JTW A;  4XT4 A;  3CD2 A;  2W9G A;  1JOM A;  2W3M A;  3QLZ A;  5HUI A;  4EIZ A;  4PTJ A;  3K74 A;  3NXT A;  1VDR A;  1PD9 A;  1QZF A;  4NX6 A;  4XT5 A;  3R33 A;  1DRE A;  1MVS A;  5CCC A;  4HOG A;  1E26 A;  3IRN A;  4KJJ A;  4OR7 A;  2D5N A;  1S3V A;  3GHC A;  5CC9 A;  1DIU A;  4FHB A;  3F91 A;  3KFY A;  1U72 A;  3QL0 A;  1RX5 A;  4M7V A;  3TQ9 A;  1DHF A;  1DG5 A;  1DR1 A;  3DRC A;  1CD2 A;  3QFX A;  3JW3 A;  5U27 A;  3EEM A;  1RD7 A;  3KJS A;  3I3R A;  3NXO A;  4QI9 A;  1VJ3 A;  3EEJ A;  3FYV X;  3JWC A;  1IA4 A;  1LY4 A;  4I13 A;  5DXV A;  2C2T A;  4ELH A;  3CL9 A;  4XRB A;  1RX9 A;  2DHF A;  1DR5 A;  3SRQ X;  1RH3 A;  3D84 X;  3NZ9 X;  2FZI A;  3TQ8 A;  1DYH A;  3QL3 A;  4X5I A;  3S3V A;  3KGY A;  3CLB A;  3ZPC A;  3RO9 A;  3IRO A;  4M6J A;  1U70 A;  3Q1H A;  3L3R A;  5E8Q A;  2ZZA A;  2FZJ A;  4XEC X;  4ECK A;  1ZDR A;  3SH2 A;  1S3W A;  3F0Q X;  1DHI A;  2HM9 A;  3FY9 X;  2INQ A;  3QLR A;  4PTH A;  3EIG A;  1RF7 A;  3F0B X;  4ELF A;  1DR4 A;  1AO8 A;  4KLX A;  4KM2 A;  1DR7 A;  4KY8 A;  1RA1 A;  4X5G A;  1YHO A;  4P3Q A;  1J3K A;  2AZN A;  4ELB A;  3JWM A;  4ELE A;  3UM5 A;  3UM8 A;  3NZ6 X;  3F8Z A;  3FL8 A;  4KAK A;  3DGA A;  5HSR A;  4DDR A;  3FRF X;  2W3W A;  3LG4 A;  5HF2 X;  1TDR A;  1OHK A;  3VCO A;  1DIS A;  5HPB A;  3DAU A;  3FQV A;  2BLA A;  1DRH A;  4XT6 A;  1JOL A;  2W9S A;  1J3I A;  2KGK A;  4LEK X;  3F0X X;  3OCH A;  1D1G A;  5U26 A;  4IXE D;  4I1N A;  4KY4 A;  3FQZ A;  5HVE A;  5ECC A;  1DR3 A;  3DL5 A;  3FQO A;  3FRD X;  4PSS A;  2LF1 A;  3F0U X;  1S3U A;  4XE6 X;  3F0V X;  4EJ1 A;  4KM0 A;  4M2X A;  1RX6 A;  3INV A;  5EAJ A;  4EIL A;  4GH8 A;  3FRB X;  1LY3 A;  1OHJ A;  4DPH A;  3UM6 A;  3QGT A;  3CSE A;  3SRS X;  3FRE X;  2O7P A;  2DRC A;  3F0S X;  3NXX A;  1LUD A;  1IA3 A;  3FYW X;  5HI6 A;  4HA9 A;  3ZPG A;  1RA8 A;  3EEK A;  5HSU A;  3GI2 A;  3F8Y A;  2OBC A;  3FQF A;  1MVT A;  3IA5 A;  2BLB A;  4CD2 A;  3N0H A;  3JW5 A;  4KFJ A;  3KJR A;  4P68 A;  1DLS A;  3JVX A;  3NZD A;  3EX8 A;  3SAI A;  3SRR X;  2BLC A;  3JSU A;  1DR6 A;  4DPD A;  3S7A A;  1M78 A;  1RX7 A;  4QLE A;  1RC4 A;  3NZC X;  4QLG A;  1DYJ A;  1DAJ A;  3TQA A;  2H2Q A;  4IXG X;  3TD8 A;  4HOF A;  3SQY X;  3DL6 A;  3S9U A;  4QHV A;  3HBB A;  4TU5 X;  1IA1 A;  3DG8 A;  3IRM A;  4PST A;  1AI9 A;  4P3R A;  1DHJ A;  1RX3 A;  4KL9 A;  4KEB A;  1RA3 A;  1DDS A;  3NZB X;  1RX4 A;  4QLF A;  3NXY A;  5JA3 A;  4Q6A A;  2W3V A;  4M6L A;  3JWF A;  3D80 A;  1RX8 A;  3OAF A;  4M6K A;  3FL9 A;  4LAE X;  3EEL A;  4X5J A;  1DRF A;  1AOE A;  2W9T A;  1RB2 A;  3QYO A;  2CIG A;  3FQ0 A;  2FZH A;  1RA9 A;  3SR5 X;  5HT4 A;  2XW7 A;  1KLK A;  3GHW A;  4FGG A;  4PSY A;  2BL9 A;  3QLX A;  4DFR A;  3SA1 A;  2ANQ A;  3JWK A;  4PDJ A;  2P4G A;  1BOZ A;  1CZ3 A;  1IA2 A;  4Q0E A;  5DFR A;  1RG7 A;  4HA7 A;  3IX9 A;  4XT7 A;  1DG7 A;  4RGC A;  1DRB A;  3SA2 A;  4H98 A;  5FDA A;  3DFR A;  4KJK A;  3K47 A;  3GHV A;  2W9H A;  1RE7 A;  1DYR A;  3E0B A;  1RB3 A;  5JG0 X;  2ITH A;  6DFR A;  3M09 A;  3SRU X;  4XT8 A;  3NRR A;  1M7A A;  4QJC A;  4LAH X;  4EIG A;  5HVB A;  3I8A X;  4X5H A;  3SGY A;  2JYB A;  4G3M A;  1J3J A;  2D0K A;  1DR2 A;  2W3B A;  1HFQ A;  3RG9 A;  3FY8 X;  2HQP A;  7DFR A;  2OIP A;  4Q67 A;  2QK8 A;  4KYA A;  2L28 A;  5HQY A;  4NX7 A;  3QLS A;  4KNE A; 
#chains in the Genus database with same CATH homology
 1RX1 A;  5HF0 X;  3KY8 A;  4KBN A;  1HFR A;  3K2H A;  3FRA X;  1HFP A;  1BZF A;  1DDR A;  2CD2 A;  1JUV A;  1DLR A;  4P66 A;  2GD9 A;  1PD8 A;  3QYL A;  3QLY A;  4G8Z X;  4G95 A;  8DFR A;  4M7U A;  4KD7 A;  4H95 A;  4HOE A;  4OSG A;  3K45 A;  3DAT A;  1SEJ A;  3NU0 A;  4ELG A;  5HT5 A;  3TQB A;  1S3Y A;  1DYI A;  4H97 A;  1RA2 A;  3ROA A;  3IA4 A;  1U71 A;  4LAG X;  1KMS A;  1PDB A;  4Q0D A;  5ECX A;  4KJL A;  5HQZ A;  2W3A A;  2B3Z A;  2HXV A;  3FS6 A;  4QJZ D;  3SRW X;  3QLW A;  3NZA X;  4H96 A;  4FGH A;  3M08 A;  2G6V A;  3NXV A;  3GYF A;  3NXR A;  3NTZ A;  1KMV A;  3FQC A;  2ANO A;  3HJ3 A;  1M79 A;  4IXF X;  4X5F A;  2C2S A;  1DG8 A;  1DF7 A;  1DRA A;  4DP3 A;  3QG2 A;  1RX2 A;  3JTW A;  4XT4 A;  3CD2 A;  2W9G A;  1JOM A;  2W3M A;  3QLZ A;  5HUI A;  4EIZ A;  4PTJ A;  3K74 A;  3NXT A;  1VDR A;  1PD9 A;  1QZF A;  4NX6 A;  4XT5 A;  3R33 A;  1DRE A;  1MVS A;  5CCC A;  4HOG A;  1E26 A;  3IRN A;  4KJJ A;  4OR7 A;  2D5N A;  1S3V A;  3GHC A;  5CC9 A;  1DIU A;  4FHB A;  3F91 A;  3KFY A;  1U72 A;  3QL0 A;  1RX5 A;  4M7V A;  3TQ9 A;  1DHF A;  1DG5 A;  1DR1 A;  3DRC A;  1CD2 A;  3QFX A;  3JW3 A;  5U27 A;  3EEM A;  1RD7 A;  3KJS A;  3I3R A;  3NXO A;  4QI9 A;  1VJ3 A;  3EEJ A;  3FYV X;  3JWC A;  1IA4 A;  1LY4 A;  4I13 A;  5DXV A;  2C2T A;  4ELH A;  3CL9 A;  4XRB A;  1RX9 A;  2DHF A;  1DR5 A;  3SRQ X;  1RH3 A;  3D84 X;  3NZ9 X;  2FZI A;  3TQ8 A;  1DYH A;  3QL3 A;  4X5I A;  3S3V A;  3KGY A;  3CLB A;  3ZPC A;  3RO9 A;  3IRO A;  4M6J A;  1U70 A;  3Q1H A;  3L3R A;  5E8Q A;  2ZZA A;  2FZJ A;  4XEC X;  4ECK A;  1ZDR A;  3SH2 A;  1S3W A;  3F0Q X;  1DHI A;  2HM9 A;  3FY9 X;  2INQ A;  3QLR A;  4PTH A;  3EIG A;  1RF7 A;  3F0B X;  4ELF A;  1DR4 A;  1AO8 A;  4KLX A;  4KM2 A;  1DR7 A;  4KY8 A;  1RA1 A;  4X5G A;  1YHO A;  4P3Q A;  1J3K A;  2AZN A;  4ELB A;  3JWM A;  4ELE A;  3UM5 A;  3UM8 A;  3NZ6 X;  3F8Z A;  3FL8 A;  4KAK A;  3DGA A;  5HSR A;  4DDR A;  3FRF X;  2W3W A;  3LG4 A;  5HF2 X;  1TDR A;  1OHK A;  3VCO A;  1DIS A;  5HPB A;  3DAU A;  3FQV A;  2BLA A;  1DRH A;  4XT6 A;  1JOL A;  2W9S A;  1J3I A;  2KGK A;  4LEK X;  3F0X X;  3OCH A;  1D1G A;  5U26 A;  4IXE D;  4I1N A;  4KY4 A;  3FQZ A;  5HVE A;  5ECC A;  1DR3 A;  3DL5 A;  3FQO A;  3FRD X;  4PSS A;  2LF1 A;  3F0U X;  1S3U A;  4XE6 X;  3F0V X;  4EJ1 A;  4KM0 A;  4M2X A;  1RX6 A;  3INV A;  5EAJ A;  4EIL A;  4GH8 A;  3FRB X;  1LY3 A;  1OHJ A;  4DPH A;  3UM6 A;  3QGT A;  3CSE A;  3SRS X;  3FRE X;  2O7P A;  2DRC A;  3F0S X;  3NXX A;  1LUD A;  1IA3 A;  3FYW X;  5HI6 A;  4HA9 A;  3ZPG A;  1RA8 A;  3EEK A;  5HSU A;  3GI2 A;  3F8Y A;  2OBC A;  3FQF A;  1MVT A;  3IA5 A;  2BLB A;  4CD2 A;  3N0H A;  3JW5 A;  4KFJ A;  3KJR A;  4P68 A;  1DLS A;  3JVX A;  3NZD A;  3EX8 A;  3SAI A;  3SRR X;  2BLC A;  3JSU A;  1DR6 A;  4DPD A;  3S7A A;  1M78 A;  1RX7 A;  4QLE A;  1RC4 A;  3NZC X;  4QLG A;  1DYJ A;  1DAJ A;  3TQA A;  2H2Q A;  4IXG X;  3TD8 A;  4HOF A;  3SQY X;  3DL6 A;  3S9U A;  4QHV A;  3HBB A;  4TU5 X;  1IA1 A;  3DG8 A;  3IRM A;  4PST A;  1AI9 A;  4P3R A;  1DHJ A;  1RX3 A;  4KL9 A;  4KEB A;  1RA3 A;  1DDS A;  3NZB X;  1RX4 A;  4QLF A;  3NXY A;  5JA3 A;  4Q6A A;  2W3V A;  4M6L A;  3JWF A;  3D80 A;  1RX8 A;  3OAF A;  4M6K A;  3FL9 A;  4LAE X;  3EEL A;  4X5J A;  1DRF A;  1AOE A;  2W9T A;  1RB2 A;  3QYO A;  2CIG A;  3FQ0 A;  2FZH A;  1RA9 A;  3SR5 X;  5HT4 A;  2XW7 A;  1KLK A;  3GHW A;  4FGG A;  4PSY A;  2BL9 A;  3QLX A;  4DFR A;  3SA1 A;  2ANQ A;  3JWK A;  4PDJ A;  2P4G A;  1BOZ A;  1CZ3 A;  1IA2 A;  4Q0E A;  5DFR A;  1RG7 A;  4HA7 A;  3IX9 A;  4XT7 A;  1DG7 A;  4RGC A;  1DRB A;  3SA2 A;  4H98 A;  5FDA A;  3DFR A;  4KJK A;  3K47 A;  3GHV A;  2W9H A;  1RE7 A;  1DYR A;  3E0B A;  1RB3 A;  5JG0 X;  2ITH A;  6DFR A;  3M09 A;  3SRU X;  4XT8 A;  3NRR A;  1M7A A;  4QJC A;  4LAH X;  4EIG A;  5HVB A;  3I8A X;  4X5H A;  3SGY A;  2JYB A;  4G3M A;  1J3J A;  2D0K A;  1DR2 A;  2W3B A;  1HFQ A;  3RG9 A;  3FY8 X;  2HQP A;  7DFR A;  2OIP A;  4Q67 A;  2QK8 A;  4KYA A;  2L28 A;  5HQY A;  4NX7 A;  3QLS A;  4KNE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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