3F0BX

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-10-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3f0bX00
3ZPCA 1HFQA 3EIGA 4G8ZX 1U70A 5HQZA 1RX8A 4ELGA 3SA2A 3NXOA 4ELEA 2BL9A 4DPHA 1S3VA 3F0VX 1DHIA 1DYRA 4P66A 1HFRA 4X5FA 3JWKA 5HPBA 3F0XX 3I3RA 4KFJA 3IRNA 2QK8A 1DRFA 4KNEA 4I1NA 4OSGA 3KY8A 1IA2A 4P68A 1D1GA 3NXTA 4M6LA 3N0HA 3NXXA 1KLKA 1TDRA 4XECX 3GHWA 4XT6A 7DFRA 3NXYA 2BLBA 1DR6A 3TQ9A 4FHBA 3EELA 1DISA 2INQA 4PDJA 4KD7A 1DRBA 1SEJA 5HT4A 4M2XA 3FREX 5CC9A 1RA3A 3K74A 4XE6X 2BLCA 3QG2A 5HUIA 3DG8A 5ECCA 3GHVA 2GD9A 3SAIA 1DYIA 5HF2X 3CD2A 3IX9A 2H2QA 3VCOA 2D5NA 3EEJA 4LAGX 3FRDX 3R33A 4M7UA 3SRSX 5HI6A 4KBNA 4PSSA 4QLEA 2W9HA 3DGAA 4EJ1A 4HOGA 3QLWA 4EIZA 4HOEA 5HF0X 1DHFA 5ECXA 2W3WA 4X5GA 1DR7A 3OAFA 1YHOA 3L3RA 1DRHA 3FS6A 3JWMA 4TU5X 1RA8A 1RX1A 1DR3A 1PDBA 4RGCA 2FZHA 2XW7A 3SRQX 3Q1HA 4I13A 1RC4A 4PSYA 2W3BA 1DG5A 4LAHX 4QI9A 3NRRA 4ELHA 5DFRA 1DIUA 3NU0A 2DRCA 4HOFA 1S3YA 3F8YA 3JTWA 4Q67A 4M6JA 1CZ3A 1M7AA 3FYWX 5JA3A 1VDRA 1LY4A 1DR2A 3NZBX 3TD8A 3FL9A 1U71A 3M09A 4XRBA 3FRAX 4KL9A 2C2SA 3NZ6X 3KFYA 4PTHA 4ELFA 3FQ0A 1LY3A 3JVXA 1DREA 1AOEA 2CD2A 4CD2A 1RX9A 2P4GA 3SGYA 1J3JA 1RX5A 2C2TA 4KAKA 3JSUA 4X5IA 1RX7A 3IA5A 3FRFX 1RX3A 3K2HA 3FQZA 2ZZAA 2O7PA 3HJ3A 4M6KA 4QLGA 3E0BA 1E26A 3NZDA 3KGYA 1DYJA 4IXED 4DFRA 4DPDA 2W3VA 1S3WA 3INVA 4LAEX 1RB3A 1JOLA 2CIGA 3IROA 4M7VA 1ZDRA 2G6VA 4DDRA 2B3ZA 1RG7A 3NZAX 1MVSA 2FZJA 3ZPGA 3F8ZA 4X5JA 3TQBA 4KY8A 1DR5A 3NTZA 1M78A 2OBCA 1JOMA 5FDAA 6DFRA 3F0UX 3M08A 3FY8X 5CCCA 2BLAA 3SA1A 3JWCA 3NXVA 2OIPA 4HA7A 1BZFA 3QYLA 5EAJA 1RH3A 2W9GA 4NX6A 3QLSA 4P3QA 3FYVX 3TQ8A 1RA1A 2W3AA 1DHJA 1DR1A 4LEKX 3EEKA 4QHVA 4KJKA 5JG0X 1AO8A 4HA9A 4Q0EA 4G95A 1VJ3A 3SRWX 1DDSA 4ECKA 1DF7A 4KY4A 3FQCA 2W3MA 1RX6A 3CLBA 3KJRA 3F0SX 2AZNA 3IRMA 3F91A 8DFRA 2DHFA 2KGKA 4H97A 4H98A 3FQFA 3SQYX 1KMSA 4GH8A 3DFRA 2HM9A 1MVTA 3F0BX 2ANOA 3OCHA 3UM8A 4EIGA 1M79A 1JUVA 2LF1A 4PTJA 4KJJA 2HXVA 3F0QX 2FZIA 3CSEA 4NX7A 1DG8A 4KM2A 3JW5A 4Q0DA 3ROAA 1IA1A 1U72A 1OHKA 3QLZA 3CL9A 4OR7A 4IXFX 3EX8A 1DLRA 3GI2A 4Q6AA 4QJZD 4DP3A 3EEMA 4QLFA 1J3KA 2ITHA 3SH2A 3UM5A 4G3MA 3S7AA 2HQPA 3FL8A 1J3IA 1KMVA 1PD9A 5U27A 3RO9A 3LG4A 1RE7A 1DYHA 3S9UA 1QZFA 3FQVA 4EILA 4XT5A 2JYBA 3FRBX 2D0KA 1S3UA 3FQOA 3QGTA 2W9TA 5HVEA 3DRCA 5HSUA 3KJSA 3K47A 4FGGA 3FY9X 3QLRA 3DATA 4IXGX 1DAJA 4H95A 3SR5X 1LUDA 1DRAA 3DAUA 4KLXA 3HBBA 2W9SA 5HQYA 1BOZA 1DG7A 3NXRA 4H96A 1PD8A 4KJLA 3K45A 3QL0A 1RA2A 1RF7A 5U26A 4KEBA 3DL6A 4P3RA 2ANQA 1HFPA 1IA3A 2L28A 1RD7A 3QLYA 3RG9A 5HVBA 3S3VA 3SRUX 3NZ9X 3D80A 3IA4A 1RA9A 4X5HA 3I8AX 4XT4A 4PSTA 4KM0A 4FGHA 5E8QA 1DDRA 1RB2A 3QL3A 3JW3A 3D84X 5HSRA 3TQAA 1RX2A 3DL5A 3NZCX 3GYFA 3JWFA 4ELBA 1OHJA 3SRRX 4KYAA 4XT8A 3QFXA 1DR4A 4XT7A 1IA4A 3QYOA 1DLSA 3GHCA 1CD2A 1AI9A 5DXVA 1RX4A 4QJCA 5HT5A 3UM6A 3QLXA
chains in the Genus database with same CATH superfamily
3ZPCA 1HFQA 3EIGA 4G8ZX 1U70A 5HQZA 1RX8A 4ELGA 3SA2A 3NXOA 4ELEA 2BL9A 4DPHA 1S3VA 3F0VX 1DHIA 1DYRA 4P66A 1HFRA 4X5FA 3JWKA 5HPBA 3F0XX 3I3RA 4KFJA 3IRNA 2QK8A 1DRFA 4KNEA 4I1NA 4OSGA 3KY8A 1IA2A 4P68A 1D1GA 3NXTA 4M6LA 3N0HA 3NXXA 1KLKA 1TDRA 4XECX 3GHWA 4XT6A 7DFRA 3NXYA 2BLBA 1DR6A 3TQ9A 4FHBA 3EELA 1DISA 2INQA 4PDJA 4KD7A 1DRBA 1SEJA 5HT4A 4M2XA 3FREX 5CC9A 1RA3A 3K74A 4XE6X 2BLCA 3QG2A 5HUIA 3DG8A 5ECCA 3GHVA 2GD9A 3SAIA 1DYIA 5HF2X 3CD2A 3IX9A 2H2QA 3VCOA 2D5NA 3EEJA 4LAGX 3FRDX 3R33A 4M7UA 3SRSX 5HI6A 4KBNA 4PSSA 4QLEA 2W9HA 3DGAA 4EJ1A 4HOGA 3QLWA 4EIZA 4HOEA 5HF0X 1DHFA 5ECXA 2W3WA 4X5GA 1DR7A 3OAFA 1YHOA 3L3RA 1DRHA 3FS6A 3JWMA 4TU5X 1RA8A 1RX1A 1DR3A 1PDBA 4RGCA 2FZHA 2XW7A 3SRQX 3Q1HA 4I13A 1RC4A 4PSYA 2W3BA 1DG5A 4LAHX 4QI9A 3NRRA 4ELHA 5DFRA 1DIUA 3NU0A 2DRCA 4HOFA 1S3YA 3F8YA 3JTWA 4Q67A 4M6JA 1CZ3A 1M7AA 3FYWX 5JA3A 1VDRA 1LY4A 1DR2A 3NZBX 3TD8A 3FL9A 1U71A 3M09A 4XRBA 3FRAX 4KL9A 2C2SA 3NZ6X 3KFYA 4PTHA 4ELFA 3FQ0A 1LY3A 3JVXA 1DREA 1AOEA 2CD2A 4CD2A 1RX9A 2P4GA 3SGYA 1J3JA 1RX5A 2C2TA 4KAKA 3JSUA 4X5IA 1RX7A 3IA5A 3FRFX 1RX3A 3K2HA 3FQZA 2ZZAA 2O7PA 3HJ3A 4M6KA 4QLGA 3E0BA 1E26A 3NZDA 3KGYA 1DYJA 4IXED 4DFRA 4DPDA 2W3VA 1S3WA 3INVA 4LAEX 1RB3A 1JOLA 2CIGA 3IROA 4M7VA 1ZDRA 2G6VA 4DDRA 2B3ZA 1RG7A 3NZAX 1MVSA 2FZJA 3ZPGA 3F8ZA 4X5JA 3TQBA 4KY8A 1DR5A 3NTZA 1M78A 2OBCA 1JOMA 5FDAA 6DFRA 3F0UX 3M08A 3FY8X 5CCCA 2BLAA 3SA1A 3JWCA 3NXVA 2OIPA 4HA7A 1BZFA 3QYLA 5EAJA 1RH3A 2W9GA 4NX6A 3QLSA 4P3QA 3FYVX 3TQ8A 1RA1A 2W3AA 1DHJA 1DR1A 4LEKX 3EEKA 4QHVA 4KJKA 5JG0X 1AO8A 4HA9A 4Q0EA 4G95A 1VJ3A 3SRWX 1DDSA 4ECKA 1DF7A 4KY4A 3FQCA 2W3MA 1RX6A 3CLBA 3KJRA 3F0SX 2AZNA 3IRMA 3F91A 8DFRA 2DHFA 2KGKA 4H97A 4H98A 3FQFA 3SQYX 1KMSA 4GH8A 3DFRA 2HM9A 1MVTA 3F0BX 2ANOA 3OCHA 3UM8A 4EIGA 1M79A 1JUVA 2LF1A 4PTJA 4KJJA 2HXVA 3F0QX 2FZIA 3CSEA 4NX7A 1DG8A 4KM2A 3JW5A 4Q0DA 3ROAA 1IA1A 1U72A 1OHKA 3QLZA 3CL9A 4OR7A 4IXFX 3EX8A 1DLRA 3GI2A 4Q6AA 4QJZD 4DP3A 3EEMA 4QLFA 1J3KA 2ITHA 3SH2A 3UM5A 4G3MA 3S7AA 2HQPA 3FL8A 1J3IA 1KMVA 1PD9A 5U27A 3RO9A 3LG4A 1RE7A 1DYHA 3S9UA 1QZFA 3FQVA 4EILA 4XT5A 2JYBA 3FRBX 2D0KA 1S3UA 3FQOA 3QGTA 2W9TA 5HVEA 3DRCA 5HSUA 3KJSA 3K47A 4FGGA 3FY9X 3QLRA 3DATA 4IXGX 1DAJA 4H95A 3SR5X 1LUDA 1DRAA 3DAUA 4KLXA 3HBBA 2W9SA 5HQYA 1BOZA 1DG7A 3NXRA 4H96A 1PD8A 4KJLA 3K45A 3QL0A 1RA2A 1RF7A 5U26A 4KEBA 3DL6A 4P3RA 2ANQA 1HFPA 1IA3A 2L28A 1RD7A 3QLYA 3RG9A 5HVBA 3S3VA 3SRUX 3NZ9X 3D80A 3IA4A 1RA9A 4X5HA 3I8AX 4XT4A 4PSTA 4KM0A 4FGHA 5E8QA 1DDRA 1RB2A 3QL3A 3JW3A 3D84X 5HSRA 3TQAA 1RX2A 3DL5A 3NZCX 3GYFA 3JWFA 4ELBA 1OHJA 3SRRX 4KYAA 4XT8A 3QFXA 1DR4A 4XT7A 1IA4A 3QYOA 1DLSA 3GHCA 1CD2A 1AI9A 5DXVA 1RX4A 4QJCA 5HT5A 3UM6A 3QLXA
chains in the Genus database with same CATH topology
3ZPCA 1HFQA 3EIGA 4G8ZX 1U70A 5HQZA 1RX8A 4ELGA 3SA2A 3NXOA 4ELEA 2BL9A 4DPHA 1S3VA 3F0VX 1DHIA 1DYRA 4P66A 1HFRA 4X5FA 3JWKA 5HPBA 3F0XX 3I3RA 4KFJA 3IRNA 2QK8A 1DRFA 4KNEA 4I1NA 4OSGA 3KY8A 1IA2A 4P68A 1D1GA 3NXTA 4M6LA 3N0HA 3NXXA 1KLKA 1TDRA 4XECX 3GHWA 4XT6A 7DFRA 3NXYA 2BLBA 1DR6A 3TQ9A 4FHBA 3EELA 1DISA 2INQA 4PDJA 4KD7A 1DRBA 1SEJA 5HT4A 4M2XA 3FREX 5CC9A 1RA3A 3K74A 4XE6X 2BLCA 3QG2A 5HUIA 3DG8A 5ECCA 3GHVA 2GD9A 3SAIA 1DYIA 5HF2X 3CD2A 3IX9A 2H2QA 3VCOA 2D5NA 3EEJA 4LAGX 3FRDX 3R33A 4M7UA 3SRSX 5HI6A 4KBNA 4PSSA 4QLEA 2W9HA 3DGAA 4EJ1A 4HOGA 3QLWA 4EIZA 4HOEA 5HF0X 1DHFA 5ECXA 2W3WA 4X5GA 1DR7A 3OAFA 1YHOA 3L3RA 1DRHA 3FS6A 3JWMA 4TU5X 1RA8A 1RX1A 1DR3A 1PDBA 4RGCA 2FZHA 2XW7A 3SRQX 3Q1HA 4I13A 1RC4A 4PSYA 2W3BA 1DG5A 4LAHX 4QI9A 3NRRA 4ELHA 5DFRA 1DIUA 3NU0A 2DRCA 4HOFA 1S3YA 3F8YA 3JTWA 4Q67A 4M6JA 1CZ3A 1M7AA 3FYWX 5JA3A 1VDRA 1LY4A 1DR2A 3NZBX 3TD8A 3FL9A 1U71A 3M09A 4XRBA 3FRAX 4KL9A 2C2SA 3NZ6X 3KFYA 4PTHA 4ELFA 3FQ0A 1LY3A 3JVXA 1DREA 1AOEA 2CD2A 4CD2A 1RX9A 2P4GA 3SGYA 1J3JA 1RX5A 2C2TA 4KAKA 3JSUA 4X5IA 1RX7A 3IA5A 3FRFX 1RX3A 3K2HA 3FQZA 2ZZAA 2O7PA 3HJ3A 4M6KA 4QLGA 3E0BA 1E26A 3NZDA 3KGYA 1DYJA 4IXED 4DFRA 4DPDA 2W3VA 1S3WA 3INVA 4LAEX 1RB3A 1JOLA 2CIGA 3IROA 4M7VA 1ZDRA 2G6VA 4DDRA 2B3ZA 1RG7A 3NZAX 1MVSA 2FZJA 3ZPGA 3F8ZA 4X5JA 3TQBA 4KY8A 1DR5A 3NTZA 1M78A 2OBCA 1JOMA 5FDAA 6DFRA 3F0UX 3M08A 3FY8X 5CCCA 2BLAA 3SA1A 3JWCA 3NXVA 2OIPA 4HA7A 1BZFA 3QYLA 5EAJA 1RH3A 2W9GA 4NX6A 3QLSA 4P3QA 3FYVX 3TQ8A 1RA1A 2W3AA 1DHJA 1DR1A 4LEKX 3EEKA 4QHVA 4KJKA 5JG0X 1AO8A 4HA9A 4Q0EA 4G95A 1VJ3A 3SRWX 1DDSA 4ECKA 1DF7A 4KY4A 3FQCA 2W3MA 1RX6A 3CLBA 3KJRA 3F0SX 2AZNA 3IRMA 3F91A 8DFRA 2DHFA 2KGKA 4H97A 4H98A 3FQFA 3SQYX 1KMSA 4GH8A 3DFRA 2HM9A 1MVTA 3F0BX 2ANOA 3OCHA 3UM8A 4EIGA 1M79A 1JUVA 2LF1A 4PTJA 4KJJA 2HXVA 3F0QX 2FZIA 3CSEA 4NX7A 1DG8A 4KM2A 3JW5A 4Q0DA 3ROAA 1IA1A 1U72A 1OHKA 3QLZA 3CL9A 4OR7A 4IXFX 3EX8A 1DLRA 3GI2A 4Q6AA 4QJZD 4DP3A 3EEMA 4QLFA 1J3KA 2ITHA 3SH2A 3UM5A 4G3MA 3S7AA 2HQPA 3FL8A 1J3IA 1KMVA 1PD9A 5U27A 3RO9A 3LG4A 1RE7A 1DYHA 3S9UA 1QZFA 3FQVA 4EILA 4XT5A 2JYBA 3FRBX 2D0KA 1S3UA 3FQOA 3QGTA 2W9TA 5HVEA 3DRCA 5HSUA 3KJSA 3K47A 4FGGA 3FY9X 3QLRA 3DATA 4IXGX 1DAJA 4H95A 3SR5X 1LUDA 1DRAA 3DAUA 4KLXA 3HBBA 2W9SA 5HQYA 1BOZA 1DG7A 3NXRA 4H96A 1PD8A 4KJLA 3K45A 3QL0A 1RA2A 1RF7A 5U26A 4KEBA 3DL6A 4P3RA 2ANQA 1HFPA 1IA3A 2L28A 1RD7A 3QLYA 3RG9A 5HVBA 3S3VA 3SRUX 3NZ9X 3D80A 3IA4A 1RA9A 4X5HA 3I8AX 4XT4A 4PSTA 4KM0A 4FGHA 5E8QA 1DDRA 1RB2A 3QL3A 3JW3A 3D84X 5HSRA 3TQAA 1RX2A 3DL5A 3NZCX 3GYFA 3JWFA 4ELBA 1OHJA 3SRRX 4KYAA 4XT8A 3QFXA 1DR4A 4XT7A 1IA4A 3QYOA 1DLSA 3GHCA 1CD2A 1AI9A 5DXVA 1RX4A 4QJCA 5HT5A 3UM6A 3QLXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZPC A;  1HFQ A;  3EIG A;  4G8Z X;  1U70 A;  5HQZ A;  1RX8 A;  4ELG A;  3SA2 A;  3NXO A;  4ELE A;  2BL9 A;  4DPH A;  1S3V A;  3F0V X;  1DHI A;  1DYR A;  4P66 A;  1HFR A;  4X5F A;  3JWK A;  5HPB A;  3F0X X;  3I3R A;  4KFJ A;  3IRN A;  2QK8 A;  1DRF A;  4KNE A;  4I1N A;  4OSG A;  3KY8 A;  1IA2 A;  4P68 A;  1D1G A;  3NXT A;  4M6L A;  3N0H A;  3NXX A;  1KLK A;  1TDR A;  4XEC X;  3GHW A;  4XT6 A;  7DFR A;  3NXY A;  2BLB A;  1DR6 A;  3TQ9 A;  4FHB A;  3EEL A;  1DIS A;  2INQ A;  4PDJ A;  4KD7 A;  1DRB A;  1SEJ A;  5HT4 A;  4M2X A;  3FRE X;  5CC9 A;  1RA3 A;  3K74 A;  4XE6 X;  2BLC A;  3QG2 A;  5HUI A;  3DG8 A;  5ECC A;  3GHV A;  2GD9 A;  3SAI A;  1DYI A;  5HF2 X;  3CD2 A;  3IX9 A;  2H2Q A;  3VCO A;  2D5N A;  3EEJ A;  4LAG X;  3FRD X;  3R33 A;  4M7U A;  3SRS X;  5HI6 A;  4KBN A;  4PSS A;  4QLE A;  2W9H A;  3DGA A;  4EJ1 A;  4HOG A;  3QLW A;  4EIZ A;  4HOE A;  5HF0 X;  1DHF A;  5ECX A;  2W3W A;  4X5G A;  1DR7 A;  3OAF A;  1YHO A;  3L3R A;  1DRH A;  3FS6 A;  3JWM A;  4TU5 X;  1RA8 A;  1RX1 A;  1DR3 A;  1PDB A;  4RGC A;  2FZH A;  2XW7 A;  3SRQ X;  3Q1H A;  4I13 A;  1RC4 A;  4PSY A;  2W3B A;  1DG5 A;  4LAH X;  4QI9 A;  3NRR A;  4ELH A;  5DFR A;  1DIU A;  3NU0 A;  2DRC A;  4HOF A;  1S3Y A;  3F8Y A;  3JTW A;  4Q67 A;  4M6J A;  1CZ3 A;  1M7A A;  3FYW X;  5JA3 A;  1VDR A;  1LY4 A;  1DR2 A;  3NZB X;  3TD8 A;  3FL9 A;  1U71 A;  3M09 A;  4XRB A;  3FRA X;  4KL9 A;  2C2S A;  3NZ6 X;  3KFY A;  4PTH A;  4ELF A;  3FQ0 A;  1LY3 A;  3JVX A;  1DRE A;  1AOE A;  2CD2 A;  4CD2 A;  1RX9 A;  2P4G A;  3SGY A;  1J3J A;  1RX5 A;  2C2T A;  4KAK A;  3JSU A;  4X5I A;  1RX7 A;  3IA5 A;  3FRF X;  1RX3 A;  3K2H A;  3FQZ A;  2ZZA A;  2O7P A;  3HJ3 A;  4M6K A;  4QLG A;  3E0B A;  1E26 A;  3NZD A;  3KGY A;  1DYJ A;  4IXE D;  4DFR A;  4DPD A;  2W3V A;  1S3W A;  3INV A;  4LAE X;  1RB3 A;  1JOL A;  2CIG A;  3IRO A;  4M7V A;  1ZDR A;  2G6V A;  4DDR A;  2B3Z A;  1RG7 A;  3NZA X;  1MVS A;  2FZJ A;  3ZPG A;  3F8Z A;  4X5J A;  3TQB A;  4KY8 A;  1DR5 A;  3NTZ A;  1M78 A;  2OBC A;  1JOM A;  5FDA A;  6DFR A;  3F0U X;  3M08 A;  3FY8 X;  5CCC A;  2BLA A;  3SA1 A;  3JWC A;  3NXV A;  2OIP A;  4HA7 A;  1BZF A;  3QYL A;  5EAJ A;  1RH3 A;  2W9G A;  4NX6 A;  3QLS A;  4P3Q A;  3FYV X;  3TQ8 A;  1RA1 A;  2W3A A;  1DHJ A;  1DR1 A;  4LEK X;  3EEK A;  4QHV A;  4KJK A;  5JG0 X;  1AO8 A;  4HA9 A;  4Q0E A;  4G95 A;  1VJ3 A;  3SRW X;  1DDS A;  4ECK A;  1DF7 A;  4KY4 A;  3FQC A;  2W3M A;  1RX6 A;  3CLB A;  3KJR A;  3F0S X;  2AZN A;  3IRM A;  3F91 A;  8DFR A;  2DHF A;  2KGK A;  4H97 A;  4H98 A;  3FQF A;  3SQY X;  1KMS A;  4GH8 A;  3DFR A;  2HM9 A;  1MVT A;  3F0B X;  2ANO A;  3OCH A;  3UM8 A;  4EIG A;  1M79 A;  1JUV A;  2LF1 A;  4PTJ A;  4KJJ A;  2HXV A;  3F0Q X;  2FZI A;  3CSE A;  4NX7 A;  1DG8 A;  4KM2 A;  3JW5 A;  4Q0D A;  3ROA A;  1IA1 A;  1U72 A;  1OHK A;  3QLZ A;  3CL9 A;  4OR7 A;  4IXF X;  3EX8 A;  1DLR A;  3GI2 A;  4Q6A A;  4QJZ D;  4DP3 A;  3EEM A;  4QLF A;  1J3K A;  2ITH A;  3SH2 A;  3UM5 A;  4G3M A;  3S7A A;  2HQP A;  3FL8 A;  1J3I A;  1KMV A;  1PD9 A;  5U27 A;  3RO9 A;  3LG4 A;  1RE7 A;  1DYH A;  3S9U A;  1QZF A;  3FQV A;  4EIL A;  4XT5 A;  2JYB A;  3FRB X;  2D0K A;  1S3U A;  3FQO A;  3QGT A;  2W9T A;  5HVE A;  3DRC A;  5HSU A;  3KJS A;  3K47 A;  4FGG A;  3FY9 X;  3QLR A;  3DAT A;  4IXG X;  1DAJ A;  4H95 A;  3SR5 X;  1LUD A;  1DRA A;  3DAU A;  4KLX A;  3HBB A;  2W9S A;  5HQY A;  1BOZ A;  1DG7 A;  3NXR A;  4H96 A;  1PD8 A;  4KJL A;  3K45 A;  3QL0 A;  1RA2 A;  1RF7 A;  5U26 A;  4KEB A;  3DL6 A;  4P3R A;  2ANQ A;  1HFP A;  1IA3 A;  2L28 A;  1RD7 A;  3QLY A;  3RG9 A;  5HVB A;  3S3V A;  3SRU X;  3NZ9 X;  3D80 A;  3IA4 A;  1RA9 A;  4X5H A;  3I8A X;  4XT4 A;  4PST A;  4KM0 A;  4FGH A;  5E8Q A;  1DDR A;  1RB2 A;  3QL3 A;  3JW3 A;  3D84 X;  5HSR A;  3TQA A;  1RX2 A;  3DL5 A;  3NZC X;  3GYF A;  3JWF A;  4ELB A;  1OHJ A;  3SRR X;  4KYA A;  4XT8 A;  3QFX A;  1DR4 A;  4XT7 A;  1IA4 A;  3QYO A;  1DLS A;  3GHC A;  1CD2 A;  1AI9 A;  5DXV A;  1RX4 A;  4QJC A;  5HT5 A;  3UM6 A;  3QLX A; 
#chains in the Genus database with same CATH topology
 3ZPC A;  1HFQ A;  3EIG A;  4G8Z X;  1U70 A;  5HQZ A;  1RX8 A;  4ELG A;  3SA2 A;  3NXO A;  4ELE A;  2BL9 A;  4DPH A;  1S3V A;  3F0V X;  1DHI A;  1DYR A;  4P66 A;  1HFR A;  4X5F A;  3JWK A;  5HPB A;  3F0X X;  3I3R A;  4KFJ A;  3IRN A;  2QK8 A;  1DRF A;  4KNE A;  4I1N A;  4OSG A;  3KY8 A;  1IA2 A;  4P68 A;  1D1G A;  3NXT A;  4M6L A;  3N0H A;  3NXX A;  1KLK A;  1TDR A;  4XEC X;  3GHW A;  4XT6 A;  7DFR A;  3NXY A;  2BLB A;  1DR6 A;  3TQ9 A;  4FHB A;  3EEL A;  1DIS A;  2INQ A;  4PDJ A;  4KD7 A;  1DRB A;  1SEJ A;  5HT4 A;  4M2X A;  3FRE X;  5CC9 A;  1RA3 A;  3K74 A;  4XE6 X;  2BLC A;  3QG2 A;  5HUI A;  3DG8 A;  5ECC A;  3GHV A;  2GD9 A;  3SAI A;  1DYI A;  5HF2 X;  3CD2 A;  3IX9 A;  2H2Q A;  3VCO A;  2D5N A;  3EEJ A;  4LAG X;  3FRD X;  3R33 A;  4M7U A;  3SRS X;  5HI6 A;  4KBN A;  4PSS A;  4QLE A;  2W9H A;  3DGA A;  4EJ1 A;  4HOG A;  3QLW A;  4EIZ A;  4HOE A;  5HF0 X;  1DHF A;  5ECX A;  2W3W A;  4X5G A;  1DR7 A;  3OAF A;  1YHO A;  3L3R A;  1DRH A;  3FS6 A;  3JWM A;  4TU5 X;  1RA8 A;  1RX1 A;  1DR3 A;  1PDB A;  4RGC A;  2FZH A;  2XW7 A;  3SRQ X;  3Q1H A;  4I13 A;  1RC4 A;  4PSY A;  2W3B A;  1DG5 A;  4LAH X;  4QI9 A;  3NRR A;  4ELH A;  5DFR A;  1DIU A;  3NU0 A;  2DRC A;  4HOF A;  1S3Y A;  3F8Y A;  3JTW A;  4Q67 A;  4M6J A;  1CZ3 A;  1M7A A;  3FYW X;  5JA3 A;  1VDR A;  1LY4 A;  1DR2 A;  3NZB X;  3TD8 A;  3FL9 A;  1U71 A;  3M09 A;  4XRB A;  3FRA X;  4KL9 A;  2C2S A;  3NZ6 X;  3KFY A;  4PTH A;  4ELF A;  3FQ0 A;  1LY3 A;  3JVX A;  1DRE A;  1AOE A;  2CD2 A;  4CD2 A;  1RX9 A;  2P4G A;  3SGY A;  1J3J A;  1RX5 A;  2C2T A;  4KAK A;  3JSU A;  4X5I A;  1RX7 A;  3IA5 A;  3FRF X;  1RX3 A;  3K2H A;  3FQZ A;  2ZZA A;  2O7P A;  3HJ3 A;  4M6K A;  4QLG A;  3E0B A;  1E26 A;  3NZD A;  3KGY A;  1DYJ A;  4IXE D;  4DFR A;  4DPD A;  2W3V A;  1S3W A;  3INV A;  4LAE X;  1RB3 A;  1JOL A;  2CIG A;  3IRO A;  4M7V A;  1ZDR A;  2G6V A;  4DDR A;  2B3Z A;  1RG7 A;  3NZA X;  1MVS A;  2FZJ A;  3ZPG A;  3F8Z A;  4X5J A;  3TQB A;  4KY8 A;  1DR5 A;  3NTZ A;  1M78 A;  2OBC A;  1JOM A;  5FDA A;  6DFR A;  3F0U X;  3M08 A;  3FY8 X;  5CCC A;  2BLA A;  3SA1 A;  3JWC A;  3NXV A;  2OIP A;  4HA7 A;  1BZF A;  3QYL A;  5EAJ A;  1RH3 A;  2W9G A;  4NX6 A;  3QLS A;  4P3Q A;  3FYV X;  3TQ8 A;  1RA1 A;  2W3A A;  1DHJ A;  1DR1 A;  4LEK X;  3EEK A;  4QHV A;  4KJK A;  5JG0 X;  1AO8 A;  4HA9 A;  4Q0E A;  4G95 A;  1VJ3 A;  3SRW X;  1DDS A;  4ECK A;  1DF7 A;  4KY4 A;  3FQC A;  2W3M A;  1RX6 A;  3CLB A;  3KJR A;  3F0S X;  2AZN A;  3IRM A;  3F91 A;  8DFR A;  2DHF A;  2KGK A;  4H97 A;  4H98 A;  3FQF A;  3SQY X;  1KMS A;  4GH8 A;  3DFR A;  2HM9 A;  1MVT A;  3F0B X;  2ANO A;  3OCH A;  3UM8 A;  4EIG A;  1M79 A;  1JUV A;  2LF1 A;  4PTJ A;  4KJJ A;  2HXV A;  3F0Q X;  2FZI A;  3CSE A;  4NX7 A;  1DG8 A;  4KM2 A;  3JW5 A;  4Q0D A;  3ROA A;  1IA1 A;  1U72 A;  1OHK A;  3QLZ A;  3CL9 A;  4OR7 A;  4IXF X;  3EX8 A;  1DLR A;  3GI2 A;  4Q6A A;  4QJZ D;  4DP3 A;  3EEM A;  4QLF A;  1J3K A;  2ITH A;  3SH2 A;  3UM5 A;  4G3M A;  3S7A A;  2HQP A;  3FL8 A;  1J3I A;  1KMV A;  1PD9 A;  5U27 A;  3RO9 A;  3LG4 A;  1RE7 A;  1DYH A;  3S9U A;  1QZF A;  3FQV A;  4EIL A;  4XT5 A;  2JYB A;  3FRB X;  2D0K A;  1S3U A;  3FQO A;  3QGT A;  2W9T A;  5HVE A;  3DRC A;  5HSU A;  3KJS A;  3K47 A;  4FGG A;  3FY9 X;  3QLR A;  3DAT A;  4IXG X;  1DAJ A;  4H95 A;  3SR5 X;  1LUD A;  1DRA A;  3DAU A;  4KLX A;  3HBB A;  2W9S A;  5HQY A;  1BOZ A;  1DG7 A;  3NXR A;  4H96 A;  1PD8 A;  4KJL A;  3K45 A;  3QL0 A;  1RA2 A;  1RF7 A;  5U26 A;  4KEB A;  3DL6 A;  4P3R A;  2ANQ A;  1HFP A;  1IA3 A;  2L28 A;  1RD7 A;  3QLY A;  3RG9 A;  5HVB A;  3S3V A;  3SRU X;  3NZ9 X;  3D80 A;  3IA4 A;  1RA9 A;  4X5H A;  3I8A X;  4XT4 A;  4PST A;  4KM0 A;  4FGH A;  5E8Q A;  1DDR A;  1RB2 A;  3QL3 A;  3JW3 A;  3D84 X;  5HSR A;  3TQA A;  1RX2 A;  3DL5 A;  3NZC X;  3GYF A;  3JWF A;  4ELB A;  1OHJ A;  3SRR X;  4KYA A;  4XT8 A;  3QFX A;  1DR4 A;  4XT7 A;  1IA4 A;  3QYO A;  1DLS A;  3GHC A;  1CD2 A;  1AI9 A;  5DXV A;  1RX4 A;  4QJC A;  5HT5 A;  3UM6 A;  3QLX A; 
#chains in the Genus database with same CATH homology
 3ZPC A;  1HFQ A;  3EIG A;  4G8Z X;  1U70 A;  5HQZ A;  1RX8 A;  4ELG A;  3SA2 A;  3NXO A;  4ELE A;  2BL9 A;  4DPH A;  1S3V A;  3F0V X;  1DHI A;  1DYR A;  4P66 A;  1HFR A;  4X5F A;  3JWK A;  5HPB A;  3F0X X;  3I3R A;  4KFJ A;  3IRN A;  2QK8 A;  1DRF A;  4KNE A;  4I1N A;  4OSG A;  3KY8 A;  1IA2 A;  4P68 A;  1D1G A;  3NXT A;  4M6L A;  3N0H A;  3NXX A;  1KLK A;  1TDR A;  4XEC X;  3GHW A;  4XT6 A;  7DFR A;  3NXY A;  2BLB A;  1DR6 A;  3TQ9 A;  4FHB A;  3EEL A;  1DIS A;  2INQ A;  4PDJ A;  4KD7 A;  1DRB A;  1SEJ A;  5HT4 A;  4M2X A;  3FRE X;  5CC9 A;  1RA3 A;  3K74 A;  4XE6 X;  2BLC A;  3QG2 A;  5HUI A;  3DG8 A;  5ECC A;  3GHV A;  2GD9 A;  3SAI A;  1DYI A;  5HF2 X;  3CD2 A;  3IX9 A;  2H2Q A;  3VCO A;  2D5N A;  3EEJ A;  4LAG X;  3FRD X;  3R33 A;  4M7U A;  3SRS X;  5HI6 A;  4KBN A;  4PSS A;  4QLE A;  2W9H A;  3DGA A;  4EJ1 A;  4HOG A;  3QLW A;  4EIZ A;  4HOE A;  5HF0 X;  1DHF A;  5ECX A;  2W3W A;  4X5G A;  1DR7 A;  3OAF A;  1YHO A;  3L3R A;  1DRH A;  3FS6 A;  3JWM A;  4TU5 X;  1RA8 A;  1RX1 A;  1DR3 A;  1PDB A;  4RGC A;  2FZH A;  2XW7 A;  3SRQ X;  3Q1H A;  4I13 A;  1RC4 A;  4PSY A;  2W3B A;  1DG5 A;  4LAH X;  4QI9 A;  3NRR A;  4ELH A;  5DFR A;  1DIU A;  3NU0 A;  2DRC A;  4HOF A;  1S3Y A;  3F8Y A;  3JTW A;  4Q67 A;  4M6J A;  1CZ3 A;  1M7A A;  3FYW X;  5JA3 A;  1VDR A;  1LY4 A;  1DR2 A;  3NZB X;  3TD8 A;  3FL9 A;  1U71 A;  3M09 A;  4XRB A;  3FRA X;  4KL9 A;  2C2S A;  3NZ6 X;  3KFY A;  4PTH A;  4ELF A;  3FQ0 A;  1LY3 A;  3JVX A;  1DRE A;  1AOE A;  2CD2 A;  4CD2 A;  1RX9 A;  2P4G A;  3SGY A;  1J3J A;  1RX5 A;  2C2T A;  4KAK A;  3JSU A;  4X5I A;  1RX7 A;  3IA5 A;  3FRF X;  1RX3 A;  3K2H A;  3FQZ A;  2ZZA A;  2O7P A;  3HJ3 A;  4M6K A;  4QLG A;  3E0B A;  1E26 A;  3NZD A;  3KGY A;  1DYJ A;  4IXE D;  4DFR A;  4DPD A;  2W3V A;  1S3W A;  3INV A;  4LAE X;  1RB3 A;  1JOL A;  2CIG A;  3IRO A;  4M7V A;  1ZDR A;  2G6V A;  4DDR A;  2B3Z A;  1RG7 A;  3NZA X;  1MVS A;  2FZJ A;  3ZPG A;  3F8Z A;  4X5J A;  3TQB A;  4KY8 A;  1DR5 A;  3NTZ A;  1M78 A;  2OBC A;  1JOM A;  5FDA A;  6DFR A;  3F0U X;  3M08 A;  3FY8 X;  5CCC A;  2BLA A;  3SA1 A;  3JWC A;  3NXV A;  2OIP A;  4HA7 A;  1BZF A;  3QYL A;  5EAJ A;  1RH3 A;  2W9G A;  4NX6 A;  3QLS A;  4P3Q A;  3FYV X;  3TQ8 A;  1RA1 A;  2W3A A;  1DHJ A;  1DR1 A;  4LEK X;  3EEK A;  4QHV A;  4KJK A;  5JG0 X;  1AO8 A;  4HA9 A;  4Q0E A;  4G95 A;  1VJ3 A;  3SRW X;  1DDS A;  4ECK A;  1DF7 A;  4KY4 A;  3FQC A;  2W3M A;  1RX6 A;  3CLB A;  3KJR A;  3F0S X;  2AZN A;  3IRM A;  3F91 A;  8DFR A;  2DHF A;  2KGK A;  4H97 A;  4H98 A;  3FQF A;  3SQY X;  1KMS A;  4GH8 A;  3DFR A;  2HM9 A;  1MVT A;  3F0B X;  2ANO A;  3OCH A;  3UM8 A;  4EIG A;  1M79 A;  1JUV A;  2LF1 A;  4PTJ A;  4KJJ A;  2HXV A;  3F0Q X;  2FZI A;  3CSE A;  4NX7 A;  1DG8 A;  4KM2 A;  3JW5 A;  4Q0D A;  3ROA A;  1IA1 A;  1U72 A;  1OHK A;  3QLZ A;  3CL9 A;  4OR7 A;  4IXF X;  3EX8 A;  1DLR A;  3GI2 A;  4Q6A A;  4QJZ D;  4DP3 A;  3EEM A;  4QLF A;  1J3K A;  2ITH A;  3SH2 A;  3UM5 A;  4G3M A;  3S7A A;  2HQP A;  3FL8 A;  1J3I A;  1KMV A;  1PD9 A;  5U27 A;  3RO9 A;  3LG4 A;  1RE7 A;  1DYH A;  3S9U A;  1QZF A;  3FQV A;  4EIL A;  4XT5 A;  2JYB A;  3FRB X;  2D0K A;  1S3U A;  3FQO A;  3QGT A;  2W9T A;  5HVE A;  3DRC A;  5HSU A;  3KJS A;  3K47 A;  4FGG A;  3FY9 X;  3QLR A;  3DAT A;  4IXG X;  1DAJ A;  4H95 A;  3SR5 X;  1LUD A;  1DRA A;  3DAU A;  4KLX A;  3HBB A;  2W9S A;  5HQY A;  1BOZ A;  1DG7 A;  3NXR A;  4H96 A;  1PD8 A;  4KJL A;  3K45 A;  3QL0 A;  1RA2 A;  1RF7 A;  5U26 A;  4KEB A;  3DL6 A;  4P3R A;  2ANQ A;  1HFP A;  1IA3 A;  2L28 A;  1RD7 A;  3QLY A;  3RG9 A;  5HVB A;  3S3V A;  3SRU X;  3NZ9 X;  3D80 A;  3IA4 A;  1RA9 A;  4X5H A;  3I8A X;  4XT4 A;  4PST A;  4KM0 A;  4FGH A;  5E8Q A;  1DDR A;  1RB2 A;  3QL3 A;  3JW3 A;  3D84 X;  5HSR A;  3TQA A;  1RX2 A;  3DL5 A;  3NZC X;  3GYF A;  3JWF A;  4ELB A;  1OHJ A;  3SRR X;  4KYA A;  4XT8 A;  3QFX A;  1DR4 A;  4XT7 A;  1IA4 A;  3QYO A;  1DLS A;  3GHC A;  1CD2 A;  1AI9 A;  5DXV A;  1RX4 A;  4QJC A;  5HT5 A;  3UM6 A;  3QLX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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