3F0SX

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Complexes of Wildtype and Mutant MRSA DHFR Reveal Interactions for Lead Design
rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 43
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-10-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3f0sX00
4KNEA 1DR4A 1RA9A 3UM5A 1DYRA 4KL9A 4M6LA 1DREA 1IA3A 5HT5A 3F0VX 1DRHA 4DPDA 1DR2A 2HM9A 4GH8A 3NTZA 4IXFX 3NZBX 2CD2A 1RB2A 3NU0A 4EILA 3TQ9A 3NZAX 5HSUA 3JWCA 1RX5A 3GHVA 3F8YA 5U26A 2QK8A 4KJJA 2DRCA 1DG8A 3S7AA 7DFRA 1DR1A 3FQCA 3QLWA 1DYJA 1CZ3A 4PSYA 1HFPA 1DHFA 2W9GA 4KJKA 3CSEA 1VJ3A 5U27A 1M78A 4X5IA 2FZIA 4M6JA 4IXGX 3F8ZA 1RG7A 1RA2A 4DPHA 5ECCA 3ZPGA 1JOLA 4FGHA 4XRBA 4QJCA 4M7UA 4X5JA 4LAGX 3EEKA 3JW5A 3TQAA 1AOEA 3TQ8A 1DR6A 2P4GA 3S9UA 3FREX 3VCOA 1J3JA 4Q67A 2LF1A 3FYVX 4XT4A 4KEBA 4FHBA 4QLGA 4ELEA 1DDSA 4ELGA 1JUVA 3S3VA 4PDJA 4P68A 5HF2X 5HVBA 1AO8A 5ECXA 3F0BX 4DP3A 4P66A 2W3BA 3GHWA 1OHKA 1U71A 2XW7A 3EEJA 4Q0EA 1JOMA 1TDRA 4NX6A 1DF7A 1D1GA 2C2SA 1RC4A 3DL6A 4I1NA 3QLZA 2G6VA 3IA4A 2OIPA 4ECKA 3R33A 2CIGA 3K74A 4X5GA 3NXTA 1RA8A 1J3KA 1RB3A 4DFRA 3DFRA 3UM8A 4H96A 3GYFA 2ANQA 3QLXA 1IA4A 2GD9A 3KJSA 3DAUA 4XT5A 3NZCX 4DDRA 3QLRA 4EJ1A 1DR3A 4KJLA 1DYIA 4LAEX 4EIZA 3SA2A 4XECX 1AI9A 1U70A 1DLRA 1RF7A 3FRFX 3F0QX 1RX1A 5CC9A 3NXOA 2ITHA 6DFRA 2W3MA 3JWMA 3IX9A 1DIUA 4H95A 3FQVA 5HPBA 5HSRA 1RA1A 4IXED 1DRFA 1DLSA 3UM6A 3FRBX 3FY8X 5HI6A 3QLSA 4M2XA 3IRNA 1RD7A 4XT8A 5HUIA 2HQPA 2W3WA 3F0UX 3NXRA 1S3UA 1YHOA 2HXVA 3IA5A 3SR5X 1RX7A 3E0BA 3F91A 4KM2A 2W9HA 2B3ZA 4G3MA 3K47A 1RX9A 4KD7A 4CD2A 3CL9A 1CD2A 3FRDX 4KAKA 3Q1HA 3EIGA 1J3IA 1QZFA 3QYLA 3N0HA 4G95A 3KJRA 1MVSA 3NXXA 1DISA 3ZPCA 4KLXA 4PTHA 1KMVA 4KFJA 5HF0X 3DRCA 1RX8A 3I8AX 1DG7A 4HOEA 4Q6AA 2O7PA 4XT6A 5EAJA 5DFRA 1HFRA 4LEKX 3FQOA 3INVA 3DGAA 4RGCA 3SRQX 3QFXA 4PTJA 2ZZAA 3EELA 3SRUX 4P3QA 3NZDA 4FGGA 1M79A 3SGYA 3KFYA 3DG8A 3FQFA 1LY4A 1LUDA 3DL5A 4ELFA 5DXVA 1OHJA 1DHIA 1DRAA 4HOGA 2D5NA 2W9SA 3FQZA 5E8QA 2ANOA 4P3RA 3M09A 3LG4A 3JWKA 3JSUA 3NZ9X 3NZ6X 4KY4A 3KGYA 1RX6A 3DATA 3TQBA 4QHVA 3NXVA 2W3VA 4HOFA 5CCCA 3HBBA 4TU5X 2JYBA 1RX2A 3JVXA 3SQYX 3FRAX 3M08A 3K2HA 3F0XX 2D0KA 3OCHA 3QL0A 2BLCA 3SRSX 5FDAA 4QJZD 3NXYA 1E26A 3D80A 1PDBA 3JWFA 4H98A 3FQ0A 1DG5A 3RO9A 3SRRX 1RE7A 3FL9A 4G8ZX 2AZNA 1DHJA 4NX7A 4X5FA 1RX4A 4HA7A 4KM0A 2BLAA 5HQYA 3FL8A 3IRMA 3D84X 5HQZA 1S3YA 1IA2A 1U72A 5HVEA 4OR7A 1S3WA 4HA9A 8DFRA 2DHFA 1SEJA 1DR5A 1DRBA 3KY8A 3EEMA 4KY8A 2H2QA 3CD2A 1BZFA 1MVTA 4M7VA 4KBNA 3JW3A 3IROA 3QGTA 4ELHA 1IA1A 1RX3A 1DAJA 2OBCA 1BOZA 1DDRA 3NRRA 5JG0X 5JA3A 3QYOA 1LY3A 5HT4A 1PD9A 3ROAA 4PSSA 2FZJA 1KMSA 2L28A 3CLBA 4QLFA 1M7AA 2W9TA 4M6KA 4XT7A 4ELBA 4LAHX 3GI2A 4XE6X 3QL3A 1ZDRA 1S3VA 3K45A 1HFQA 4EIGA 3SH2A 3RG9A 1RH3A 3FY9X 3EX8A 3HJ3A 1PD8A 3GHCA 4KYAA 2BLBA 3I3RA 3F0SX 2BL9A 3JTWA 3QLYA 1DYHA 3SA1A 3SAIA 3QG2A 3SRWX 4X5HA 3TD8A 4H97A 3FYWX 1DR7A 4Q0DA 1RA3A 4I13A 3FS6A 1KLKA 4OSGA 4PSTA 3OAFA 4QI9A 2C2TA 2INQA 1VDRA 2FZHA 3L3RA 4QLEA 2W3AA 2KGKA
chains in the Genus database with same CATH superfamily
4KNEA 1DR4A 1RA9A 3UM5A 1DYRA 4KL9A 4M6LA 1DREA 1IA3A 5HT5A 3F0VX 1DRHA 4DPDA 1DR2A 2HM9A 4GH8A 3NTZA 4IXFX 3NZBX 2CD2A 1RB2A 3NU0A 4EILA 3TQ9A 3NZAX 5HSUA 3JWCA 1RX5A 3GHVA 3F8YA 5U26A 2QK8A 4KJJA 2DRCA 1DG8A 3S7AA 7DFRA 1DR1A 3FQCA 3QLWA 1DYJA 1CZ3A 4PSYA 1HFPA 1DHFA 2W9GA 4KJKA 3CSEA 1VJ3A 5U27A 1M78A 4X5IA 2FZIA 4M6JA 4IXGX 3F8ZA 1RG7A 1RA2A 4DPHA 5ECCA 3ZPGA 1JOLA 4FGHA 4XRBA 4QJCA 4M7UA 4X5JA 4LAGX 3EEKA 3JW5A 3TQAA 1AOEA 3TQ8A 1DR6A 2P4GA 3S9UA 3FREX 3VCOA 1J3JA 4Q67A 2LF1A 3FYVX 4XT4A 4KEBA 4FHBA 4QLGA 4ELEA 1DDSA 4ELGA 1JUVA 3S3VA 4PDJA 4P68A 5HF2X 5HVBA 1AO8A 5ECXA 3F0BX 4DP3A 4P66A 2W3BA 3GHWA 1OHKA 1U71A 2XW7A 3EEJA 4Q0EA 1JOMA 1TDRA 4NX6A 1DF7A 1D1GA 2C2SA 1RC4A 3DL6A 4I1NA 3QLZA 2G6VA 3IA4A 2OIPA 4ECKA 3R33A 2CIGA 3K74A 4X5GA 3NXTA 1RA8A 1J3KA 1RB3A 4DFRA 3DFRA 3UM8A 4H96A 3GYFA 2ANQA 3QLXA 1IA4A 2GD9A 3KJSA 3DAUA 4XT5A 3NZCX 4DDRA 3QLRA 4EJ1A 1DR3A 4KJLA 1DYIA 4LAEX 4EIZA 3SA2A 4XECX 1AI9A 1U70A 1DLRA 1RF7A 3FRFX 3F0QX 1RX1A 5CC9A 3NXOA 2ITHA 6DFRA 2W3MA 3JWMA 3IX9A 1DIUA 4H95A 3FQVA 5HPBA 5HSRA 1RA1A 4IXED 1DRFA 1DLSA 3UM6A 3FRBX 3FY8X 5HI6A 3QLSA 4M2XA 3IRNA 1RD7A 4XT8A 5HUIA 2HQPA 2W3WA 3F0UX 3NXRA 1S3UA 1YHOA 2HXVA 3IA5A 3SR5X 1RX7A 3E0BA 3F91A 4KM2A 2W9HA 2B3ZA 4G3MA 3K47A 1RX9A 4KD7A 4CD2A 3CL9A 1CD2A 3FRDX 4KAKA 3Q1HA 3EIGA 1J3IA 1QZFA 3QYLA 3N0HA 4G95A 3KJRA 1MVSA 3NXXA 1DISA 3ZPCA 4KLXA 4PTHA 1KMVA 4KFJA 5HF0X 3DRCA 1RX8A 3I8AX 1DG7A 4HOEA 4Q6AA 2O7PA 4XT6A 5EAJA 5DFRA 1HFRA 4LEKX 3FQOA 3INVA 3DGAA 4RGCA 3SRQX 3QFXA 4PTJA 2ZZAA 3EELA 3SRUX 4P3QA 3NZDA 4FGGA 1M79A 3SGYA 3KFYA 3DG8A 3FQFA 1LY4A 1LUDA 3DL5A 4ELFA 5DXVA 1OHJA 1DHIA 1DRAA 4HOGA 2D5NA 2W9SA 3FQZA 5E8QA 2ANOA 4P3RA 3M09A 3LG4A 3JWKA 3JSUA 3NZ9X 3NZ6X 4KY4A 3KGYA 1RX6A 3DATA 3TQBA 4QHVA 3NXVA 2W3VA 4HOFA 5CCCA 3HBBA 4TU5X 2JYBA 1RX2A 3JVXA 3SQYX 3FRAX 3M08A 3K2HA 3F0XX 2D0KA 3OCHA 3QL0A 2BLCA 3SRSX 5FDAA 4QJZD 3NXYA 1E26A 3D80A 1PDBA 3JWFA 4H98A 3FQ0A 1DG5A 3RO9A 3SRRX 1RE7A 3FL9A 4G8ZX 2AZNA 1DHJA 4NX7A 4X5FA 1RX4A 4HA7A 4KM0A 2BLAA 5HQYA 3FL8A 3IRMA 3D84X 5HQZA 1S3YA 1IA2A 1U72A 5HVEA 4OR7A 1S3WA 4HA9A 8DFRA 2DHFA 1SEJA 1DR5A 1DRBA 3KY8A 3EEMA 4KY8A 2H2QA 3CD2A 1BZFA 1MVTA 4M7VA 4KBNA 3JW3A 3IROA 3QGTA 4ELHA 1IA1A 1RX3A 1DAJA 2OBCA 1BOZA 1DDRA 3NRRA 5JG0X 5JA3A 3QYOA 1LY3A 5HT4A 1PD9A 3ROAA 4PSSA 2FZJA 1KMSA 2L28A 3CLBA 4QLFA 1M7AA 2W9TA 4M6KA 4XT7A 4ELBA 4LAHX 3GI2A 4XE6X 3QL3A 1ZDRA 1S3VA 3K45A 1HFQA 4EIGA 3SH2A 3RG9A 1RH3A 3FY9X 3EX8A 3HJ3A 1PD8A 3GHCA 4KYAA 2BLBA 3I3RA 3F0SX 2BL9A 3JTWA 3QLYA 1DYHA 3SA1A 3SAIA 3QG2A 3SRWX 4X5HA 3TD8A 4H97A 3FYWX 1DR7A 4Q0DA 1RA3A 4I13A 3FS6A 1KLKA 4OSGA 4PSTA 3OAFA 4QI9A 2C2TA 2INQA 1VDRA 2FZHA 3L3RA 4QLEA 2W3AA 2KGKA
chains in the Genus database with same CATH topology
4KNEA 1DR4A 1RA9A 3UM5A 1DYRA 4KL9A 4M6LA 1DREA 1IA3A 5HT5A 3F0VX 1DRHA 4DPDA 1DR2A 2HM9A 4GH8A 3NTZA 4IXFX 3NZBX 2CD2A 1RB2A 3NU0A 4EILA 3TQ9A 3NZAX 5HSUA 3JWCA 1RX5A 3GHVA 3F8YA 5U26A 2QK8A 4KJJA 2DRCA 1DG8A 3S7AA 7DFRA 1DR1A 3FQCA 3QLWA 1DYJA 1CZ3A 4PSYA 1HFPA 1DHFA 2W9GA 4KJKA 3CSEA 1VJ3A 5U27A 1M78A 4X5IA 2FZIA 4M6JA 4IXGX 3F8ZA 1RG7A 1RA2A 4DPHA 5ECCA 3ZPGA 1JOLA 4FGHA 4XRBA 4QJCA 4M7UA 4X5JA 4LAGX 3EEKA 3JW5A 3TQAA 1AOEA 3TQ8A 1DR6A 2P4GA 3S9UA 3FREX 3VCOA 1J3JA 4Q67A 2LF1A 3FYVX 4XT4A 4KEBA 4FHBA 4QLGA 4ELEA 1DDSA 4ELGA 1JUVA 3S3VA 4PDJA 4P68A 5HF2X 5HVBA 1AO8A 5ECXA 3F0BX 4DP3A 4P66A 2W3BA 3GHWA 1OHKA 1U71A 2XW7A 3EEJA 4Q0EA 1JOMA 1TDRA 4NX6A 1DF7A 1D1GA 2C2SA 1RC4A 3DL6A 4I1NA 3QLZA 2G6VA 3IA4A 2OIPA 4ECKA 3R33A 2CIGA 3K74A 4X5GA 3NXTA 1RA8A 1J3KA 1RB3A 4DFRA 3DFRA 3UM8A 4H96A 3GYFA 2ANQA 3QLXA 1IA4A 2GD9A 3KJSA 3DAUA 4XT5A 3NZCX 4DDRA 3QLRA 4EJ1A 1DR3A 4KJLA 1DYIA 4LAEX 4EIZA 3SA2A 4XECX 1AI9A 1U70A 1DLRA 1RF7A 3FRFX 3F0QX 1RX1A 5CC9A 3NXOA 2ITHA 6DFRA 2W3MA 3JWMA 3IX9A 1DIUA 4H95A 3FQVA 5HPBA 5HSRA 1RA1A 4IXED 1DRFA 1DLSA 3UM6A 3FRBX 3FY8X 5HI6A 3QLSA 4M2XA 3IRNA 1RD7A 4XT8A 5HUIA 2HQPA 2W3WA 3F0UX 3NXRA 1S3UA 1YHOA 2HXVA 3IA5A 3SR5X 1RX7A 3E0BA 3F91A 4KM2A 2W9HA 2B3ZA 4G3MA 3K47A 1RX9A 4KD7A 4CD2A 3CL9A 1CD2A 3FRDX 4KAKA 3Q1HA 3EIGA 1J3IA 1QZFA 3QYLA 3N0HA 4G95A 3KJRA 1MVSA 3NXXA 1DISA 3ZPCA 4KLXA 4PTHA 1KMVA 4KFJA 5HF0X 3DRCA 1RX8A 3I8AX 1DG7A 4HOEA 4Q6AA 2O7PA 4XT6A 5EAJA 5DFRA 1HFRA 4LEKX 3FQOA 3INVA 3DGAA 4RGCA 3SRQX 3QFXA 4PTJA 2ZZAA 3EELA 3SRUX 4P3QA 3NZDA 4FGGA 1M79A 3SGYA 3KFYA 3DG8A 3FQFA 1LY4A 1LUDA 3DL5A 4ELFA 5DXVA 1OHJA 1DHIA 1DRAA 4HOGA 2D5NA 2W9SA 3FQZA 5E8QA 2ANOA 4P3RA 3M09A 3LG4A 3JWKA 3JSUA 3NZ9X 3NZ6X 4KY4A 3KGYA 1RX6A 3DATA 3TQBA 4QHVA 3NXVA 2W3VA 4HOFA 5CCCA 3HBBA 4TU5X 2JYBA 1RX2A 3JVXA 3SQYX 3FRAX 3M08A 3K2HA 3F0XX 2D0KA 3OCHA 3QL0A 2BLCA 3SRSX 5FDAA 4QJZD 3NXYA 1E26A 3D80A 1PDBA 3JWFA 4H98A 3FQ0A 1DG5A 3RO9A 3SRRX 1RE7A 3FL9A 4G8ZX 2AZNA 1DHJA 4NX7A 4X5FA 1RX4A 4HA7A 4KM0A 2BLAA 5HQYA 3FL8A 3IRMA 3D84X 5HQZA 1S3YA 1IA2A 1U72A 5HVEA 4OR7A 1S3WA 4HA9A 8DFRA 2DHFA 1SEJA 1DR5A 1DRBA 3KY8A 3EEMA 4KY8A 2H2QA 3CD2A 1BZFA 1MVTA 4M7VA 4KBNA 3JW3A 3IROA 3QGTA 4ELHA 1IA1A 1RX3A 1DAJA 2OBCA 1BOZA 1DDRA 3NRRA 5JG0X 5JA3A 3QYOA 1LY3A 5HT4A 1PD9A 3ROAA 4PSSA 2FZJA 1KMSA 2L28A 3CLBA 4QLFA 1M7AA 2W9TA 4M6KA 4XT7A 4ELBA 4LAHX 3GI2A 4XE6X 3QL3A 1ZDRA 1S3VA 3K45A 1HFQA 4EIGA 3SH2A 3RG9A 1RH3A 3FY9X 3EX8A 3HJ3A 1PD8A 3GHCA 4KYAA 2BLBA 3I3RA 3F0SX 2BL9A 3JTWA 3QLYA 1DYHA 3SA1A 3SAIA 3QG2A 3SRWX 4X5HA 3TD8A 4H97A 3FYWX 1DR7A 4Q0DA 1RA3A 4I13A 3FS6A 1KLKA 4OSGA 4PSTA 3OAFA 4QI9A 2C2TA 2INQA 1VDRA 2FZHA 3L3RA 4QLEA 2W3AA 2KGKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KNE A;  1DR4 A;  1RA9 A;  3UM5 A;  1DYR A;  4KL9 A;  4M6L A;  1DRE A;  1IA3 A;  5HT5 A;  3F0V X;  1DRH A;  4DPD A;  1DR2 A;  2HM9 A;  4GH8 A;  3NTZ A;  4IXF X;  3NZB X;  2CD2 A;  1RB2 A;  3NU0 A;  4EIL A;  3TQ9 A;  3NZA X;  5HSU A;  3JWC A;  1RX5 A;  3GHV A;  3F8Y A;  5U26 A;  2QK8 A;  4KJJ A;  2DRC A;  1DG8 A;  3S7A A;  7DFR A;  1DR1 A;  3FQC A;  3QLW A;  1DYJ A;  1CZ3 A;  4PSY A;  1HFP A;  1DHF A;  2W9G A;  4KJK A;  3CSE A;  1VJ3 A;  5U27 A;  1M78 A;  4X5I A;  2FZI A;  4M6J A;  4IXG X;  3F8Z A;  1RG7 A;  1RA2 A;  4DPH A;  5ECC A;  3ZPG A;  1JOL A;  4FGH A;  4XRB A;  4QJC A;  4M7U A;  4X5J A;  4LAG X;  3EEK A;  3JW5 A;  3TQA A;  1AOE A;  3TQ8 A;  1DR6 A;  2P4G A;  3S9U A;  3FRE X;  3VCO A;  1J3J A;  4Q67 A;  2LF1 A;  3FYV X;  4XT4 A;  4KEB A;  4FHB A;  4QLG A;  4ELE A;  1DDS A;  4ELG A;  1JUV A;  3S3V A;  4PDJ A;  4P68 A;  5HF2 X;  5HVB A;  1AO8 A;  5ECX A;  3F0B X;  4DP3 A;  4P66 A;  2W3B A;  3GHW A;  1OHK A;  1U71 A;  2XW7 A;  3EEJ A;  4Q0E A;  1JOM A;  1TDR A;  4NX6 A;  1DF7 A;  1D1G A;  2C2S A;  1RC4 A;  3DL6 A;  4I1N A;  3QLZ A;  2G6V A;  3IA4 A;  2OIP A;  4ECK A;  3R33 A;  2CIG A;  3K74 A;  4X5G A;  3NXT A;  1RA8 A;  1J3K A;  1RB3 A;  4DFR A;  3DFR A;  3UM8 A;  4H96 A;  3GYF A;  2ANQ A;  3QLX A;  1IA4 A;  2GD9 A;  3KJS A;  3DAU A;  4XT5 A;  3NZC X;  4DDR A;  3QLR A;  4EJ1 A;  1DR3 A;  4KJL A;  1DYI A;  4LAE X;  4EIZ A;  3SA2 A;  4XEC X;  1AI9 A;  1U70 A;  1DLR A;  1RF7 A;  3FRF X;  3F0Q X;  1RX1 A;  5CC9 A;  3NXO A;  2ITH A;  6DFR A;  2W3M A;  3JWM A;  3IX9 A;  1DIU A;  4H95 A;  3FQV A;  5HPB A;  5HSR A;  1RA1 A;  4IXE D;  1DRF A;  1DLS A;  3UM6 A;  3FRB X;  3FY8 X;  5HI6 A;  3QLS A;  4M2X A;  3IRN A;  1RD7 A;  4XT8 A;  5HUI A;  2HQP A;  2W3W A;  3F0U X;  3NXR A;  1S3U A;  1YHO A;  2HXV A;  3IA5 A;  3SR5 X;  1RX7 A;  3E0B A;  3F91 A;  4KM2 A;  2W9H A;  2B3Z A;  4G3M A;  3K47 A;  1RX9 A;  4KD7 A;  4CD2 A;  3CL9 A;  1CD2 A;  3FRD X;  4KAK A;  3Q1H A;  3EIG A;  1J3I A;  1QZF A;  3QYL A;  3N0H A;  4G95 A;  3KJR A;  1MVS A;  3NXX A;  1DIS A;  3ZPC A;  4KLX A;  4PTH A;  1KMV A;  4KFJ A;  5HF0 X;  3DRC A;  1RX8 A;  3I8A X;  1DG7 A;  4HOE A;  4Q6A A;  2O7P A;  4XT6 A;  5EAJ A;  5DFR A;  1HFR A;  4LEK X;  3FQO A;  3INV A;  3DGA A;  4RGC A;  3SRQ X;  3QFX A;  4PTJ A;  2ZZA A;  3EEL A;  3SRU X;  4P3Q A;  3NZD A;  4FGG A;  1M79 A;  3SGY A;  3KFY A;  3DG8 A;  3FQF A;  1LY4 A;  1LUD A;  3DL5 A;  4ELF A;  5DXV A;  1OHJ A;  1DHI A;  1DRA A;  4HOG A;  2D5N A;  2W9S A;  3FQZ A;  5E8Q A;  2ANO A;  4P3R A;  3M09 A;  3LG4 A;  3JWK A;  3JSU A;  3NZ9 X;  3NZ6 X;  4KY4 A;  3KGY A;  1RX6 A;  3DAT A;  3TQB A;  4QHV A;  3NXV A;  2W3V A;  4HOF A;  5CCC A;  3HBB A;  4TU5 X;  2JYB A;  1RX2 A;  3JVX A;  3SQY X;  3FRA X;  3M08 A;  3K2H A;  3F0X X;  2D0K A;  3OCH A;  3QL0 A;  2BLC A;  3SRS X;  5FDA A;  4QJZ D;  3NXY A;  1E26 A;  3D80 A;  1PDB A;  3JWF A;  4H98 A;  3FQ0 A;  1DG5 A;  3RO9 A;  3SRR X;  1RE7 A;  3FL9 A;  4G8Z X;  2AZN A;  1DHJ A;  4NX7 A;  4X5F A;  1RX4 A;  4HA7 A;  4KM0 A;  2BLA A;  5HQY A;  3FL8 A;  3IRM A;  3D84 X;  5HQZ A;  1S3Y A;  1IA2 A;  1U72 A;  5HVE A;  4OR7 A;  1S3W A;  4HA9 A;  8DFR A;  2DHF A;  1SEJ A;  1DR5 A;  1DRB A;  3KY8 A;  3EEM A;  4KY8 A;  2H2Q A;  3CD2 A;  1BZF A;  1MVT A;  4M7V A;  4KBN A;  3JW3 A;  3IRO A;  3QGT A;  4ELH A;  1IA1 A;  1RX3 A;  1DAJ A;  2OBC A;  1BOZ A;  1DDR A;  3NRR A;  5JG0 X;  5JA3 A;  3QYO A;  1LY3 A;  5HT4 A;  1PD9 A;  3ROA A;  4PSS A;  2FZJ A;  1KMS A;  2L28 A;  3CLB A;  4QLF A;  1M7A A;  2W9T A;  4M6K A;  4XT7 A;  4ELB A;  4LAH X;  3GI2 A;  4XE6 X;  3QL3 A;  1ZDR A;  1S3V A;  3K45 A;  1HFQ A;  4EIG A;  3SH2 A;  3RG9 A;  1RH3 A;  3FY9 X;  3EX8 A;  3HJ3 A;  1PD8 A;  3GHC A;  4KYA A;  2BLB A;  3I3R A;  3F0S X;  2BL9 A;  3JTW A;  3QLY A;  1DYH A;  3SA1 A;  3SAI A;  3QG2 A;  3SRW X;  4X5H A;  3TD8 A;  4H97 A;  3FYW X;  1DR7 A;  4Q0D A;  1RA3 A;  4I13 A;  3FS6 A;  1KLK A;  4OSG A;  4PST A;  3OAF A;  4QI9 A;  2C2T A;  2INQ A;  1VDR A;  2FZH A;  3L3R A;  4QLE A;  2W3A A;  2KGK A; 
#chains in the Genus database with same CATH topology
 4KNE A;  1DR4 A;  1RA9 A;  3UM5 A;  1DYR A;  4KL9 A;  4M6L A;  1DRE A;  1IA3 A;  5HT5 A;  3F0V X;  1DRH A;  4DPD A;  1DR2 A;  2HM9 A;  4GH8 A;  3NTZ A;  4IXF X;  3NZB X;  2CD2 A;  1RB2 A;  3NU0 A;  4EIL A;  3TQ9 A;  3NZA X;  5HSU A;  3JWC A;  1RX5 A;  3GHV A;  3F8Y A;  5U26 A;  2QK8 A;  4KJJ A;  2DRC A;  1DG8 A;  3S7A A;  7DFR A;  1DR1 A;  3FQC A;  3QLW A;  1DYJ A;  1CZ3 A;  4PSY A;  1HFP A;  1DHF A;  2W9G A;  4KJK A;  3CSE A;  1VJ3 A;  5U27 A;  1M78 A;  4X5I A;  2FZI A;  4M6J A;  4IXG X;  3F8Z A;  1RG7 A;  1RA2 A;  4DPH A;  5ECC A;  3ZPG A;  1JOL A;  4FGH A;  4XRB A;  4QJC A;  4M7U A;  4X5J A;  4LAG X;  3EEK A;  3JW5 A;  3TQA A;  1AOE A;  3TQ8 A;  1DR6 A;  2P4G A;  3S9U A;  3FRE X;  3VCO A;  1J3J A;  4Q67 A;  2LF1 A;  3FYV X;  4XT4 A;  4KEB A;  4FHB A;  4QLG A;  4ELE A;  1DDS A;  4ELG A;  1JUV A;  3S3V A;  4PDJ A;  4P68 A;  5HF2 X;  5HVB A;  1AO8 A;  5ECX A;  3F0B X;  4DP3 A;  4P66 A;  2W3B A;  3GHW A;  1OHK A;  1U71 A;  2XW7 A;  3EEJ A;  4Q0E A;  1JOM A;  1TDR A;  4NX6 A;  1DF7 A;  1D1G A;  2C2S A;  1RC4 A;  3DL6 A;  4I1N A;  3QLZ A;  2G6V A;  3IA4 A;  2OIP A;  4ECK A;  3R33 A;  2CIG A;  3K74 A;  4X5G A;  3NXT A;  1RA8 A;  1J3K A;  1RB3 A;  4DFR A;  3DFR A;  3UM8 A;  4H96 A;  3GYF A;  2ANQ A;  3QLX A;  1IA4 A;  2GD9 A;  3KJS A;  3DAU A;  4XT5 A;  3NZC X;  4DDR A;  3QLR A;  4EJ1 A;  1DR3 A;  4KJL A;  1DYI A;  4LAE X;  4EIZ A;  3SA2 A;  4XEC X;  1AI9 A;  1U70 A;  1DLR A;  1RF7 A;  3FRF X;  3F0Q X;  1RX1 A;  5CC9 A;  3NXO A;  2ITH A;  6DFR A;  2W3M A;  3JWM A;  3IX9 A;  1DIU A;  4H95 A;  3FQV A;  5HPB A;  5HSR A;  1RA1 A;  4IXE D;  1DRF A;  1DLS A;  3UM6 A;  3FRB X;  3FY8 X;  5HI6 A;  3QLS A;  4M2X A;  3IRN A;  1RD7 A;  4XT8 A;  5HUI A;  2HQP A;  2W3W A;  3F0U X;  3NXR A;  1S3U A;  1YHO A;  2HXV A;  3IA5 A;  3SR5 X;  1RX7 A;  3E0B A;  3F91 A;  4KM2 A;  2W9H A;  2B3Z A;  4G3M A;  3K47 A;  1RX9 A;  4KD7 A;  4CD2 A;  3CL9 A;  1CD2 A;  3FRD X;  4KAK A;  3Q1H A;  3EIG A;  1J3I A;  1QZF A;  3QYL A;  3N0H A;  4G95 A;  3KJR A;  1MVS A;  3NXX A;  1DIS A;  3ZPC A;  4KLX A;  4PTH A;  1KMV A;  4KFJ A;  5HF0 X;  3DRC A;  1RX8 A;  3I8A X;  1DG7 A;  4HOE A;  4Q6A A;  2O7P A;  4XT6 A;  5EAJ A;  5DFR A;  1HFR A;  4LEK X;  3FQO A;  3INV A;  3DGA A;  4RGC A;  3SRQ X;  3QFX A;  4PTJ A;  2ZZA A;  3EEL A;  3SRU X;  4P3Q A;  3NZD A;  4FGG A;  1M79 A;  3SGY A;  3KFY A;  3DG8 A;  3FQF A;  1LY4 A;  1LUD A;  3DL5 A;  4ELF A;  5DXV A;  1OHJ A;  1DHI A;  1DRA A;  4HOG A;  2D5N A;  2W9S A;  3FQZ A;  5E8Q A;  2ANO A;  4P3R A;  3M09 A;  3LG4 A;  3JWK A;  3JSU A;  3NZ9 X;  3NZ6 X;  4KY4 A;  3KGY A;  1RX6 A;  3DAT A;  3TQB A;  4QHV A;  3NXV A;  2W3V A;  4HOF A;  5CCC A;  3HBB A;  4TU5 X;  2JYB A;  1RX2 A;  3JVX A;  3SQY X;  3FRA X;  3M08 A;  3K2H A;  3F0X X;  2D0K A;  3OCH A;  3QL0 A;  2BLC A;  3SRS X;  5FDA A;  4QJZ D;  3NXY A;  1E26 A;  3D80 A;  1PDB A;  3JWF A;  4H98 A;  3FQ0 A;  1DG5 A;  3RO9 A;  3SRR X;  1RE7 A;  3FL9 A;  4G8Z X;  2AZN A;  1DHJ A;  4NX7 A;  4X5F A;  1RX4 A;  4HA7 A;  4KM0 A;  2BLA A;  5HQY A;  3FL8 A;  3IRM A;  3D84 X;  5HQZ A;  1S3Y A;  1IA2 A;  1U72 A;  5HVE A;  4OR7 A;  1S3W A;  4HA9 A;  8DFR A;  2DHF A;  1SEJ A;  1DR5 A;  1DRB A;  3KY8 A;  3EEM A;  4KY8 A;  2H2Q A;  3CD2 A;  1BZF A;  1MVT A;  4M7V A;  4KBN A;  3JW3 A;  3IRO A;  3QGT A;  4ELH A;  1IA1 A;  1RX3 A;  1DAJ A;  2OBC A;  1BOZ A;  1DDR A;  3NRR A;  5JG0 X;  5JA3 A;  3QYO A;  1LY3 A;  5HT4 A;  1PD9 A;  3ROA A;  4PSS A;  2FZJ A;  1KMS A;  2L28 A;  3CLB A;  4QLF A;  1M7A A;  2W9T A;  4M6K A;  4XT7 A;  4ELB A;  4LAH X;  3GI2 A;  4XE6 X;  3QL3 A;  1ZDR A;  1S3V A;  3K45 A;  1HFQ A;  4EIG A;  3SH2 A;  3RG9 A;  1RH3 A;  3FY9 X;  3EX8 A;  3HJ3 A;  1PD8 A;  3GHC A;  4KYA A;  2BLB A;  3I3R A;  3F0S X;  2BL9 A;  3JTW A;  3QLY A;  1DYH A;  3SA1 A;  3SAI A;  3QG2 A;  3SRW X;  4X5H A;  3TD8 A;  4H97 A;  3FYW X;  1DR7 A;  4Q0D A;  1RA3 A;  4I13 A;  3FS6 A;  1KLK A;  4OSG A;  4PST A;  3OAF A;  4QI9 A;  2C2T A;  2INQ A;  1VDR A;  2FZH A;  3L3R A;  4QLE A;  2W3A A;  2KGK A; 
#chains in the Genus database with same CATH homology
 4KNE A;  1DR4 A;  1RA9 A;  3UM5 A;  1DYR A;  4KL9 A;  4M6L A;  1DRE A;  1IA3 A;  5HT5 A;  3F0V X;  1DRH A;  4DPD A;  1DR2 A;  2HM9 A;  4GH8 A;  3NTZ A;  4IXF X;  3NZB X;  2CD2 A;  1RB2 A;  3NU0 A;  4EIL A;  3TQ9 A;  3NZA X;  5HSU A;  3JWC A;  1RX5 A;  3GHV A;  3F8Y A;  5U26 A;  2QK8 A;  4KJJ A;  2DRC A;  1DG8 A;  3S7A A;  7DFR A;  1DR1 A;  3FQC A;  3QLW A;  1DYJ A;  1CZ3 A;  4PSY A;  1HFP A;  1DHF A;  2W9G A;  4KJK A;  3CSE A;  1VJ3 A;  5U27 A;  1M78 A;  4X5I A;  2FZI A;  4M6J A;  4IXG X;  3F8Z A;  1RG7 A;  1RA2 A;  4DPH A;  5ECC A;  3ZPG A;  1JOL A;  4FGH A;  4XRB A;  4QJC A;  4M7U A;  4X5J A;  4LAG X;  3EEK A;  3JW5 A;  3TQA A;  1AOE A;  3TQ8 A;  1DR6 A;  2P4G A;  3S9U A;  3FRE X;  3VCO A;  1J3J A;  4Q67 A;  2LF1 A;  3FYV X;  4XT4 A;  4KEB A;  4FHB A;  4QLG A;  4ELE A;  1DDS A;  4ELG A;  1JUV A;  3S3V A;  4PDJ A;  4P68 A;  5HF2 X;  5HVB A;  1AO8 A;  5ECX A;  3F0B X;  4DP3 A;  4P66 A;  2W3B A;  3GHW A;  1OHK A;  1U71 A;  2XW7 A;  3EEJ A;  4Q0E A;  1JOM A;  1TDR A;  4NX6 A;  1DF7 A;  1D1G A;  2C2S A;  1RC4 A;  3DL6 A;  4I1N A;  3QLZ A;  2G6V A;  3IA4 A;  2OIP A;  4ECK A;  3R33 A;  2CIG A;  3K74 A;  4X5G A;  3NXT A;  1RA8 A;  1J3K A;  1RB3 A;  4DFR A;  3DFR A;  3UM8 A;  4H96 A;  3GYF A;  2ANQ A;  3QLX A;  1IA4 A;  2GD9 A;  3KJS A;  3DAU A;  4XT5 A;  3NZC X;  4DDR A;  3QLR A;  4EJ1 A;  1DR3 A;  4KJL A;  1DYI A;  4LAE X;  4EIZ A;  3SA2 A;  4XEC X;  1AI9 A;  1U70 A;  1DLR A;  1RF7 A;  3FRF X;  3F0Q X;  1RX1 A;  5CC9 A;  3NXO A;  2ITH A;  6DFR A;  2W3M A;  3JWM A;  3IX9 A;  1DIU A;  4H95 A;  3FQV A;  5HPB A;  5HSR A;  1RA1 A;  4IXE D;  1DRF A;  1DLS A;  3UM6 A;  3FRB X;  3FY8 X;  5HI6 A;  3QLS A;  4M2X A;  3IRN A;  1RD7 A;  4XT8 A;  5HUI A;  2HQP A;  2W3W A;  3F0U X;  3NXR A;  1S3U A;  1YHO A;  2HXV A;  3IA5 A;  3SR5 X;  1RX7 A;  3E0B A;  3F91 A;  4KM2 A;  2W9H A;  2B3Z A;  4G3M A;  3K47 A;  1RX9 A;  4KD7 A;  4CD2 A;  3CL9 A;  1CD2 A;  3FRD X;  4KAK A;  3Q1H A;  3EIG A;  1J3I A;  1QZF A;  3QYL A;  3N0H A;  4G95 A;  3KJR A;  1MVS A;  3NXX A;  1DIS A;  3ZPC A;  4KLX A;  4PTH A;  1KMV A;  4KFJ A;  5HF0 X;  3DRC A;  1RX8 A;  3I8A X;  1DG7 A;  4HOE A;  4Q6A A;  2O7P A;  4XT6 A;  5EAJ A;  5DFR A;  1HFR A;  4LEK X;  3FQO A;  3INV A;  3DGA A;  4RGC A;  3SRQ X;  3QFX A;  4PTJ A;  2ZZA A;  3EEL A;  3SRU X;  4P3Q A;  3NZD A;  4FGG A;  1M79 A;  3SGY A;  3KFY A;  3DG8 A;  3FQF A;  1LY4 A;  1LUD A;  3DL5 A;  4ELF A;  5DXV A;  1OHJ A;  1DHI A;  1DRA A;  4HOG A;  2D5N A;  2W9S A;  3FQZ A;  5E8Q A;  2ANO A;  4P3R A;  3M09 A;  3LG4 A;  3JWK A;  3JSU A;  3NZ9 X;  3NZ6 X;  4KY4 A;  3KGY A;  1RX6 A;  3DAT A;  3TQB A;  4QHV A;  3NXV A;  2W3V A;  4HOF A;  5CCC A;  3HBB A;  4TU5 X;  2JYB A;  1RX2 A;  3JVX A;  3SQY X;  3FRA X;  3M08 A;  3K2H A;  3F0X X;  2D0K A;  3OCH A;  3QL0 A;  2BLC A;  3SRS X;  5FDA A;  4QJZ D;  3NXY A;  1E26 A;  3D80 A;  1PDB A;  3JWF A;  4H98 A;  3FQ0 A;  1DG5 A;  3RO9 A;  3SRR X;  1RE7 A;  3FL9 A;  4G8Z X;  2AZN A;  1DHJ A;  4NX7 A;  4X5F A;  1RX4 A;  4HA7 A;  4KM0 A;  2BLA A;  5HQY A;  3FL8 A;  3IRM A;  3D84 X;  5HQZ A;  1S3Y A;  1IA2 A;  1U72 A;  5HVE A;  4OR7 A;  1S3W A;  4HA9 A;  8DFR A;  2DHF A;  1SEJ A;  1DR5 A;  1DRB A;  3KY8 A;  3EEM A;  4KY8 A;  2H2Q A;  3CD2 A;  1BZF A;  1MVT A;  4M7V A;  4KBN A;  3JW3 A;  3IRO A;  3QGT A;  4ELH A;  1IA1 A;  1RX3 A;  1DAJ A;  2OBC A;  1BOZ A;  1DDR A;  3NRR A;  5JG0 X;  5JA3 A;  3QYO A;  1LY3 A;  5HT4 A;  1PD9 A;  3ROA A;  4PSS A;  2FZJ A;  1KMS A;  2L28 A;  3CLB A;  4QLF A;  1M7A A;  2W9T A;  4M6K A;  4XT7 A;  4ELB A;  4LAH X;  3GI2 A;  4XE6 X;  3QL3 A;  1ZDR A;  1S3V A;  3K45 A;  1HFQ A;  4EIG A;  3SH2 A;  3RG9 A;  1RH3 A;  3FY9 X;  3EX8 A;  3HJ3 A;  1PD8 A;  3GHC A;  4KYA A;  2BLB A;  3I3R A;  3F0S X;  2BL9 A;  3JTW A;  3QLY A;  1DYH A;  3SA1 A;  3SAI A;  3QG2 A;  3SRW X;  4X5H A;  3TD8 A;  4H97 A;  3FYW X;  1DR7 A;  4Q0D A;  1RA3 A;  4I13 A;  3FS6 A;  1KLK A;  4OSG A;  4PST A;  3OAF A;  4QI9 A;  2C2T A;  2INQ A;  1VDR A;  2FZH A;  3L3R A;  4QLE A;  2W3A A;  2KGK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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