3F0UX

Staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 44
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-10-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3f0uX00
1U71A 4KNEA 4DP3A 3QLYA 1DRAA 1RD7A 4G3MA 3GHWA 4Q0DA 3F0QX 1RX7A 1RX9A 1DRBA 1S3UA 1RB3A 3SRUX 3GHCA 5HQYA 2BLCA 3FQOA 3E0BA 3NU0A 3R33A 2DHFA 3VCOA 1S3VA 3EIGA 3F8ZA 3JVXA 2D0KA 4XT6A 4M7UA 3JWCA 1DR4A 2BLAA 5HI6A 1RA2A 3NZDA 4H97A 3QLRA 1RX2A 3F0BX 3SA1A 4X5JA 3DL6A 4X5FA 2HXVA 4Q0EA 4QLFA 1RX8A 1DIUA 2W9TA 3ROAA 5HT4A 3NZBX 1DG5A 1LUDA 2B3ZA 3CSEA 1DG8A 2W3AA 3UM8A 3K74A 2ANOA 3OAFA 2ITHA 3EELA 5JG0X 1LY4A 1DYIA 4EIGA 3CL9A 1HFQA 1RX6A 2O7PA 4KEBA 3FQ0A 2INQA 1DLSA 2H2QA 7DFRA 1BZFA 1RC4A 3NRRA 1DR1A 4KJJA 3TQBA 3SR5X 4KJKA 3F0VX 2ANQA 4EJ1A 1KLKA 4ELBA 4M6LA 1KMSA 4P66A 3FQCA 3FQVA 1RA3A 4P68A 4FHBA 3F0SX 4DPDA 3SRRX 3HJ3A 4OR7A 3FYVX 3QGTA 3SRSX 4CD2A 1PDBA 2CIGA 3EEJA 3QYOA 3UM5A 1AI9A 4LAGX 4QHVA 1AO8A 1E26A 3JSUA 4M6KA 4H96A 1RX5A 3QFXA 1DR5A 3DRCA 3NTZA 1BOZA 1KMVA 3EX8A 3JTWA 4LAHX 3JW5A 5HT5A 2OBCA 4X5HA 2FZHA 4IXGX 3FL9A 4KYAA 3K47A 3FS6A 3CLBA 3M09A 1RX3A 3IA4A 1IA3A 1DHJA 4X5GA 1HFPA 1SEJA 3NZ9X 3I3RA 4KM2A 1J3JA 3IRNA 4KY4A 1VDRA 4KLXA 3FY8X 1DISA 4PSTA 3NXVA 4PSSA 2W9SA 4LEKX 1JOMA 4KFJA 2W9GA 4G95A 3KJRA 4KD7A 2G6VA 1IA4A 5CCCA 1OHKA 3OCHA 4XECX 1U72A 4Q67A 3NXTA 3IRMA 3QYLA 4PSYA 1PD8A 1RX4A 4NX7A 4XT7A 1M78A 4XT8A 2CD2A 2W9HA 3FQZA 2DRCA 4TU5X 1DYHA 3NXRA 2FZJA 5HPBA 3F0UX 4OSGA 1LY3A 1DYJA 3DG8A 3QLWA 4ELEA 4LAEX 4XT4A 3DATA 2P4GA 1RB2A 5DXVA 3GHVA 3UM6A 3SA2A 1DR2A 1DLRA 4M6JA 4Q6AA 1YHOA 3S3VA 3DL5A 3NZ6X 1DDRA 3DAUA 2BLBA 1DREA 3DGAA 5JA3A 1MVSA 5U26A 4ECKA 4GH8A 5FDAA 4KY8A 3DFRA 2GD9A 3ZPCA 5HSRA 2LF1A 3K45A 2W3BA 1DG7A 3QL0A 5ECCA 3FRBX 3N0HA 4RGCA 5E8QA 2W3VA 1DHFA 2JYBA 3SAIA 2W3WA 3GI2A 5EAJA 1DHIA 1RE7A 3JWMA 3D80A 3JW3A 4IXED 2XW7A 3TQ9A 4XT5A 4KL9A 3NXYA 3L3RA 1RA1A 2C2SA 1RA9A 3F91A 4IXFX 1M79A 3KY8A 4EIZA 3QLSA 4H98A 4HA9A 3NZAX 3FREX 3RG9A 3SQYX 4KBNA 2ZZAA 3SRWX 1DAJA 3QG2A 4HOFA 1DDSA 8DFRA 1JOLA 1DRHA 4ELGA 4FGHA 3K2HA 4EILA 5CC9A 5HVBA 4P3RA 1VJ3A 4PDJA 4QI9A 1J3KA 4M7VA 3FYWX 2C2TA 3SH2A 4H95A 4P3QA 1OHJA 3FRDX 1IA1A 1IA2A 3JWKA 2OIPA 4HOGA 2AZNA 3RO9A 3JWFA 3LG4A 4QJCA 4KM0A 3S7AA 1CZ3A 3I8AX 1J3IA 5DFRA 2KGKA 4HA7A 3KGYA 3F8YA 5HVEA 4PTJA 2D5NA 3GYFA 4PTHA 3FRAX 4XRBA 4KAKA 3IX9A 4X5IA 1RG7A 5U27A 6DFRA 3Q1HA 2HM9A 1RH3A 3TQ8A 4HOEA 1S3WA 3KFYA 3KJSA 5HUIA 3SRQX 4I1NA 3FY9X 1DYRA 1ZDRA 1HFRA 2HQPA 3M08A 4FGGA 1CD2A 2L28A 3F0XX 4QLEA 1RF7A 3EEMA 3IROA 1DR3A 2FZIA 4M2XA 4DFRA 4XE6X 5HQZA 3QLXA 3ZPGA 2BL9A 1JUVA 4ELFA 1RX1A 3FRFX 3CD2A 1DRFA 3QLZA 1DR6A 4I13A 1S3YA 5ECXA 1U70A 3SGYA 1TDRA 3QL3A 3NXXA 1D1GA 3FQFA 3S9UA 1AOEA 1M7AA 3EEKA 1QZFA 4NX6A 1DR7A 4DDRA 4G8ZX 5HSUA 3TD8A 3FL8A 4QJZD 4ELHA 1RA8A 3HBBA 2QK8A 2W3MA 3D84X 3NXOA 5HF2X 4DPHA 4KJLA 3TQAA 3NZCX 1MVTA 4QLGA 5HF0X 3IA5A 1PD9A 1DF7A 3INVA
chains in the Genus database with same CATH superfamily
1U71A 4KNEA 4DP3A 3QLYA 1DRAA 1RD7A 4G3MA 3GHWA 4Q0DA 3F0QX 1RX7A 1RX9A 1DRBA 1S3UA 1RB3A 3SRUX 3GHCA 5HQYA 2BLCA 3FQOA 3E0BA 3NU0A 3R33A 2DHFA 3VCOA 1S3VA 3EIGA 3F8ZA 3JVXA 2D0KA 4XT6A 4M7UA 3JWCA 1DR4A 2BLAA 5HI6A 1RA2A 3NZDA 4H97A 3QLRA 1RX2A 3F0BX 3SA1A 4X5JA 3DL6A 4X5FA 2HXVA 4Q0EA 4QLFA 1RX8A 1DIUA 2W9TA 3ROAA 5HT4A 3NZBX 1DG5A 1LUDA 2B3ZA 3CSEA 1DG8A 2W3AA 3UM8A 3K74A 2ANOA 3OAFA 2ITHA 3EELA 5JG0X 1LY4A 1DYIA 4EIGA 3CL9A 1HFQA 1RX6A 2O7PA 4KEBA 3FQ0A 2INQA 1DLSA 2H2QA 7DFRA 1BZFA 1RC4A 3NRRA 1DR1A 4KJJA 3TQBA 3SR5X 4KJKA 3F0VX 2ANQA 4EJ1A 1KLKA 4ELBA 4M6LA 1KMSA 4P66A 3FQCA 3FQVA 1RA3A 4P68A 4FHBA 3F0SX 4DPDA 3SRRX 3HJ3A 4OR7A 3FYVX 3QGTA 3SRSX 4CD2A 1PDBA 2CIGA 3EEJA 3QYOA 3UM5A 1AI9A 4LAGX 4QHVA 1AO8A 1E26A 3JSUA 4M6KA 4H96A 1RX5A 3QFXA 1DR5A 3DRCA 3NTZA 1BOZA 1KMVA 3EX8A 3JTWA 4LAHX 3JW5A 5HT5A 2OBCA 4X5HA 2FZHA 4IXGX 3FL9A 4KYAA 3K47A 3FS6A 3CLBA 3M09A 1RX3A 3IA4A 1IA3A 1DHJA 4X5GA 1HFPA 1SEJA 3NZ9X 3I3RA 4KM2A 1J3JA 3IRNA 4KY4A 1VDRA 4KLXA 3FY8X 1DISA 4PSTA 3NXVA 4PSSA 2W9SA 4LEKX 1JOMA 4KFJA 2W9GA 4G95A 3KJRA 4KD7A 2G6VA 1IA4A 5CCCA 1OHKA 3OCHA 4XECX 1U72A 4Q67A 3NXTA 3IRMA 3QYLA 4PSYA 1PD8A 1RX4A 4NX7A 4XT7A 1M78A 4XT8A 2CD2A 2W9HA 3FQZA 2DRCA 4TU5X 1DYHA 3NXRA 2FZJA 5HPBA 3F0UX 4OSGA 1LY3A 1DYJA 3DG8A 3QLWA 4ELEA 4LAEX 4XT4A 3DATA 2P4GA 1RB2A 5DXVA 3GHVA 3UM6A 3SA2A 1DR2A 1DLRA 4M6JA 4Q6AA 1YHOA 3S3VA 3DL5A 3NZ6X 1DDRA 3DAUA 2BLBA 1DREA 3DGAA 5JA3A 1MVSA 5U26A 4ECKA 4GH8A 5FDAA 4KY8A 3DFRA 2GD9A 3ZPCA 5HSRA 2LF1A 3K45A 2W3BA 1DG7A 3QL0A 5ECCA 3FRBX 3N0HA 4RGCA 5E8QA 2W3VA 1DHFA 2JYBA 3SAIA 2W3WA 3GI2A 5EAJA 1DHIA 1RE7A 3JWMA 3D80A 3JW3A 4IXED 2XW7A 3TQ9A 4XT5A 4KL9A 3NXYA 3L3RA 1RA1A 2C2SA 1RA9A 3F91A 4IXFX 1M79A 3KY8A 4EIZA 3QLSA 4H98A 4HA9A 3NZAX 3FREX 3RG9A 3SQYX 4KBNA 2ZZAA 3SRWX 1DAJA 3QG2A 4HOFA 1DDSA 8DFRA 1JOLA 1DRHA 4ELGA 4FGHA 3K2HA 4EILA 5CC9A 5HVBA 4P3RA 1VJ3A 4PDJA 4QI9A 1J3KA 4M7VA 3FYWX 2C2TA 3SH2A 4H95A 4P3QA 1OHJA 3FRDX 1IA1A 1IA2A 3JWKA 2OIPA 4HOGA 2AZNA 3RO9A 3JWFA 3LG4A 4QJCA 4KM0A 3S7AA 1CZ3A 3I8AX 1J3IA 5DFRA 2KGKA 4HA7A 3KGYA 3F8YA 5HVEA 4PTJA 2D5NA 3GYFA 4PTHA 3FRAX 4XRBA 4KAKA 3IX9A 4X5IA 1RG7A 5U27A 6DFRA 3Q1HA 2HM9A 1RH3A 3TQ8A 4HOEA 1S3WA 3KFYA 3KJSA 5HUIA 3SRQX 4I1NA 3FY9X 1DYRA 1ZDRA 1HFRA 2HQPA 3M08A 4FGGA 1CD2A 2L28A 3F0XX 4QLEA 1RF7A 3EEMA 3IROA 1DR3A 2FZIA 4M2XA 4DFRA 4XE6X 5HQZA 3QLXA 3ZPGA 2BL9A 1JUVA 4ELFA 1RX1A 3FRFX 3CD2A 1DRFA 3QLZA 1DR6A 4I13A 1S3YA 5ECXA 1U70A 3SGYA 1TDRA 3QL3A 3NXXA 1D1GA 3FQFA 3S9UA 1AOEA 1M7AA 3EEKA 1QZFA 4NX6A 1DR7A 4DDRA 4G8ZX 5HSUA 3TD8A 3FL8A 4QJZD 4ELHA 1RA8A 3HBBA 2QK8A 2W3MA 3D84X 3NXOA 5HF2X 4DPHA 4KJLA 3TQAA 3NZCX 1MVTA 4QLGA 5HF0X 3IA5A 1PD9A 1DF7A 3INVA
chains in the Genus database with same CATH topology
1U71A 4KNEA 4DP3A 3QLYA 1DRAA 1RD7A 4G3MA 3GHWA 4Q0DA 3F0QX 1RX7A 1RX9A 1DRBA 1S3UA 1RB3A 3SRUX 3GHCA 5HQYA 2BLCA 3FQOA 3E0BA 3NU0A 3R33A 2DHFA 3VCOA 1S3VA 3EIGA 3F8ZA 3JVXA 2D0KA 4XT6A 4M7UA 3JWCA 1DR4A 2BLAA 5HI6A 1RA2A 3NZDA 4H97A 3QLRA 1RX2A 3F0BX 3SA1A 4X5JA 3DL6A 4X5FA 2HXVA 4Q0EA 4QLFA 1RX8A 1DIUA 2W9TA 3ROAA 5HT4A 3NZBX 1DG5A 1LUDA 2B3ZA 3CSEA 1DG8A 2W3AA 3UM8A 3K74A 2ANOA 3OAFA 2ITHA 3EELA 5JG0X 1LY4A 1DYIA 4EIGA 3CL9A 1HFQA 1RX6A 2O7PA 4KEBA 3FQ0A 2INQA 1DLSA 2H2QA 7DFRA 1BZFA 1RC4A 3NRRA 1DR1A 4KJJA 3TQBA 3SR5X 4KJKA 3F0VX 2ANQA 4EJ1A 1KLKA 4ELBA 4M6LA 1KMSA 4P66A 3FQCA 3FQVA 1RA3A 4P68A 4FHBA 3F0SX 4DPDA 3SRRX 3HJ3A 4OR7A 3FYVX 3QGTA 3SRSX 4CD2A 1PDBA 2CIGA 3EEJA 3QYOA 3UM5A 1AI9A 4LAGX 4QHVA 1AO8A 1E26A 3JSUA 4M6KA 4H96A 1RX5A 3QFXA 1DR5A 3DRCA 3NTZA 1BOZA 1KMVA 3EX8A 3JTWA 4LAHX 3JW5A 5HT5A 2OBCA 4X5HA 2FZHA 4IXGX 3FL9A 4KYAA 3K47A 3FS6A 3CLBA 3M09A 1RX3A 3IA4A 1IA3A 1DHJA 4X5GA 1HFPA 1SEJA 3NZ9X 3I3RA 4KM2A 1J3JA 3IRNA 4KY4A 1VDRA 4KLXA 3FY8X 1DISA 4PSTA 3NXVA 4PSSA 2W9SA 4LEKX 1JOMA 4KFJA 2W9GA 4G95A 3KJRA 4KD7A 2G6VA 1IA4A 5CCCA 1OHKA 3OCHA 4XECX 1U72A 4Q67A 3NXTA 3IRMA 3QYLA 4PSYA 1PD8A 1RX4A 4NX7A 4XT7A 1M78A 4XT8A 2CD2A 2W9HA 3FQZA 2DRCA 4TU5X 1DYHA 3NXRA 2FZJA 5HPBA 3F0UX 4OSGA 1LY3A 1DYJA 3DG8A 3QLWA 4ELEA 4LAEX 4XT4A 3DATA 2P4GA 1RB2A 5DXVA 3GHVA 3UM6A 3SA2A 1DR2A 1DLRA 4M6JA 4Q6AA 1YHOA 3S3VA 3DL5A 3NZ6X 1DDRA 3DAUA 2BLBA 1DREA 3DGAA 5JA3A 1MVSA 5U26A 4ECKA 4GH8A 5FDAA 4KY8A 3DFRA 2GD9A 3ZPCA 5HSRA 2LF1A 3K45A 2W3BA 1DG7A 3QL0A 5ECCA 3FRBX 3N0HA 4RGCA 5E8QA 2W3VA 1DHFA 2JYBA 3SAIA 2W3WA 3GI2A 5EAJA 1DHIA 1RE7A 3JWMA 3D80A 3JW3A 4IXED 2XW7A 3TQ9A 4XT5A 4KL9A 3NXYA 3L3RA 1RA1A 2C2SA 1RA9A 3F91A 4IXFX 1M79A 3KY8A 4EIZA 3QLSA 4H98A 4HA9A 3NZAX 3FREX 3RG9A 3SQYX 4KBNA 2ZZAA 3SRWX 1DAJA 3QG2A 4HOFA 1DDSA 8DFRA 1JOLA 1DRHA 4ELGA 4FGHA 3K2HA 4EILA 5CC9A 5HVBA 4P3RA 1VJ3A 4PDJA 4QI9A 1J3KA 4M7VA 3FYWX 2C2TA 3SH2A 4H95A 4P3QA 1OHJA 3FRDX 1IA1A 1IA2A 3JWKA 2OIPA 4HOGA 2AZNA 3RO9A 3JWFA 3LG4A 4QJCA 4KM0A 3S7AA 1CZ3A 3I8AX 1J3IA 5DFRA 2KGKA 4HA7A 3KGYA 3F8YA 5HVEA 4PTJA 2D5NA 3GYFA 4PTHA 3FRAX 4XRBA 4KAKA 3IX9A 4X5IA 1RG7A 5U27A 6DFRA 3Q1HA 2HM9A 1RH3A 3TQ8A 4HOEA 1S3WA 3KFYA 3KJSA 5HUIA 3SRQX 4I1NA 3FY9X 1DYRA 1ZDRA 1HFRA 2HQPA 3M08A 4FGGA 1CD2A 2L28A 3F0XX 4QLEA 1RF7A 3EEMA 3IROA 1DR3A 2FZIA 4M2XA 4DFRA 4XE6X 5HQZA 3QLXA 3ZPGA 2BL9A 1JUVA 4ELFA 1RX1A 3FRFX 3CD2A 1DRFA 3QLZA 1DR6A 4I13A 1S3YA 5ECXA 1U70A 3SGYA 1TDRA 3QL3A 3NXXA 1D1GA 3FQFA 3S9UA 1AOEA 1M7AA 3EEKA 1QZFA 4NX6A 1DR7A 4DDRA 4G8ZX 5HSUA 3TD8A 3FL8A 4QJZD 4ELHA 1RA8A 3HBBA 2QK8A 2W3MA 3D84X 3NXOA 5HF2X 4DPHA 4KJLA 3TQAA 3NZCX 1MVTA 4QLGA 5HF0X 3IA5A 1PD9A 1DF7A 3INVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U71 A;  4KNE A;  4DP3 A;  3QLY A;  1DRA A;  1RD7 A;  4G3M A;  3GHW A;  4Q0D A;  3F0Q X;  1RX7 A;  1RX9 A;  1DRB A;  1S3U A;  1RB3 A;  3SRU X;  3GHC A;  5HQY A;  2BLC A;  3FQO A;  3E0B A;  3NU0 A;  3R33 A;  2DHF A;  3VCO A;  1S3V A;  3EIG A;  3F8Z A;  3JVX A;  2D0K A;  4XT6 A;  4M7U A;  3JWC A;  1DR4 A;  2BLA A;  5HI6 A;  1RA2 A;  3NZD A;  4H97 A;  3QLR A;  1RX2 A;  3F0B X;  3SA1 A;  4X5J A;  3DL6 A;  4X5F A;  2HXV A;  4Q0E A;  4QLF A;  1RX8 A;  1DIU A;  2W9T A;  3ROA A;  5HT4 A;  3NZB X;  1DG5 A;  1LUD A;  2B3Z A;  3CSE A;  1DG8 A;  2W3A A;  3UM8 A;  3K74 A;  2ANO A;  3OAF A;  2ITH A;  3EEL A;  5JG0 X;  1LY4 A;  1DYI A;  4EIG A;  3CL9 A;  1HFQ A;  1RX6 A;  2O7P A;  4KEB A;  3FQ0 A;  2INQ A;  1DLS A;  2H2Q A;  7DFR A;  1BZF A;  1RC4 A;  3NRR A;  1DR1 A;  4KJJ A;  3TQB A;  3SR5 X;  4KJK A;  3F0V X;  2ANQ A;  4EJ1 A;  1KLK A;  4ELB A;  4M6L A;  1KMS A;  4P66 A;  3FQC A;  3FQV A;  1RA3 A;  4P68 A;  4FHB A;  3F0S X;  4DPD A;  3SRR X;  3HJ3 A;  4OR7 A;  3FYV X;  3QGT A;  3SRS X;  4CD2 A;  1PDB A;  2CIG A;  3EEJ A;  3QYO A;  3UM5 A;  1AI9 A;  4LAG X;  4QHV A;  1AO8 A;  1E26 A;  3JSU A;  4M6K A;  4H96 A;  1RX5 A;  3QFX A;  1DR5 A;  3DRC A;  3NTZ A;  1BOZ A;  1KMV A;  3EX8 A;  3JTW A;  4LAH X;  3JW5 A;  5HT5 A;  2OBC A;  4X5H A;  2FZH A;  4IXG X;  3FL9 A;  4KYA A;  3K47 A;  3FS6 A;  3CLB A;  3M09 A;  1RX3 A;  3IA4 A;  1IA3 A;  1DHJ A;  4X5G A;  1HFP A;  1SEJ A;  3NZ9 X;  3I3R A;  4KM2 A;  1J3J A;  3IRN A;  4KY4 A;  1VDR A;  4KLX A;  3FY8 X;  1DIS A;  4PST A;  3NXV A;  4PSS A;  2W9S A;  4LEK X;  1JOM A;  4KFJ A;  2W9G A;  4G95 A;  3KJR A;  4KD7 A;  2G6V A;  1IA4 A;  5CCC A;  1OHK A;  3OCH A;  4XEC X;  1U72 A;  4Q67 A;  3NXT A;  3IRM A;  3QYL A;  4PSY A;  1PD8 A;  1RX4 A;  4NX7 A;  4XT7 A;  1M78 A;  4XT8 A;  2CD2 A;  2W9H A;  3FQZ A;  2DRC A;  4TU5 X;  1DYH A;  3NXR A;  2FZJ A;  5HPB A;  3F0U X;  4OSG A;  1LY3 A;  1DYJ A;  3DG8 A;  3QLW A;  4ELE A;  4LAE X;  4XT4 A;  3DAT A;  2P4G A;  1RB2 A;  5DXV A;  3GHV A;  3UM6 A;  3SA2 A;  1DR2 A;  1DLR A;  4M6J A;  4Q6A A;  1YHO A;  3S3V A;  3DL5 A;  3NZ6 X;  1DDR A;  3DAU A;  2BLB A;  1DRE A;  3DGA A;  5JA3 A;  1MVS A;  5U26 A;  4ECK A;  4GH8 A;  5FDA A;  4KY8 A;  3DFR A;  2GD9 A;  3ZPC A;  5HSR A;  2LF1 A;  3K45 A;  2W3B A;  1DG7 A;  3QL0 A;  5ECC A;  3FRB X;  3N0H A;  4RGC A;  5E8Q A;  2W3V A;  1DHF A;  2JYB A;  3SAI A;  2W3W A;  3GI2 A;  5EAJ A;  1DHI A;  1RE7 A;  3JWM A;  3D80 A;  3JW3 A;  4IXE D;  2XW7 A;  3TQ9 A;  4XT5 A;  4KL9 A;  3NXY A;  3L3R A;  1RA1 A;  2C2S A;  1RA9 A;  3F91 A;  4IXF X;  1M79 A;  3KY8 A;  4EIZ A;  3QLS A;  4H98 A;  4HA9 A;  3NZA X;  3FRE X;  3RG9 A;  3SQY X;  4KBN A;  2ZZA A;  3SRW X;  1DAJ A;  3QG2 A;  4HOF A;  1DDS A;  8DFR A;  1JOL A;  1DRH A;  4ELG A;  4FGH A;  3K2H A;  4EIL A;  5CC9 A;  5HVB A;  4P3R A;  1VJ3 A;  4PDJ A;  4QI9 A;  1J3K A;  4M7V A;  3FYW X;  2C2T A;  3SH2 A;  4H95 A;  4P3Q A;  1OHJ A;  3FRD X;  1IA1 A;  1IA2 A;  3JWK A;  2OIP A;  4HOG A;  2AZN A;  3RO9 A;  3JWF A;  3LG4 A;  4QJC A;  4KM0 A;  3S7A A;  1CZ3 A;  3I8A X;  1J3I A;  5DFR A;  2KGK A;  4HA7 A;  3KGY A;  3F8Y A;  5HVE A;  4PTJ A;  2D5N A;  3GYF A;  4PTH A;  3FRA X;  4XRB A;  4KAK A;  3IX9 A;  4X5I A;  1RG7 A;  5U27 A;  6DFR A;  3Q1H A;  2HM9 A;  1RH3 A;  3TQ8 A;  4HOE A;  1S3W A;  3KFY A;  3KJS A;  5HUI A;  3SRQ X;  4I1N A;  3FY9 X;  1DYR A;  1ZDR A;  1HFR A;  2HQP A;  3M08 A;  4FGG A;  1CD2 A;  2L28 A;  3F0X X;  4QLE A;  1RF7 A;  3EEM A;  3IRO A;  1DR3 A;  2FZI A;  4M2X A;  4DFR A;  4XE6 X;  5HQZ A;  3QLX A;  3ZPG A;  2BL9 A;  1JUV A;  4ELF A;  1RX1 A;  3FRF X;  3CD2 A;  1DRF A;  3QLZ A;  1DR6 A;  4I13 A;  1S3Y A;  5ECX A;  1U70 A;  3SGY A;  1TDR A;  3QL3 A;  3NXX A;  1D1G A;  3FQF A;  3S9U A;  1AOE A;  1M7A A;  3EEK A;  1QZF A;  4NX6 A;  1DR7 A;  4DDR A;  4G8Z X;  5HSU A;  3TD8 A;  3FL8 A;  4QJZ D;  4ELH A;  1RA8 A;  3HBB A;  2QK8 A;  2W3M A;  3D84 X;  3NXO A;  5HF2 X;  4DPH A;  4KJL A;  3TQA A;  3NZC X;  1MVT A;  4QLG A;  5HF0 X;  3IA5 A;  1PD9 A;  1DF7 A;  3INV A; 
#chains in the Genus database with same CATH topology
 1U71 A;  4KNE A;  4DP3 A;  3QLY A;  1DRA A;  1RD7 A;  4G3M A;  3GHW A;  4Q0D A;  3F0Q X;  1RX7 A;  1RX9 A;  1DRB A;  1S3U A;  1RB3 A;  3SRU X;  3GHC A;  5HQY A;  2BLC A;  3FQO A;  3E0B A;  3NU0 A;  3R33 A;  2DHF A;  3VCO A;  1S3V A;  3EIG A;  3F8Z A;  3JVX A;  2D0K A;  4XT6 A;  4M7U A;  3JWC A;  1DR4 A;  2BLA A;  5HI6 A;  1RA2 A;  3NZD A;  4H97 A;  3QLR A;  1RX2 A;  3F0B X;  3SA1 A;  4X5J A;  3DL6 A;  4X5F A;  2HXV A;  4Q0E A;  4QLF A;  1RX8 A;  1DIU A;  2W9T A;  3ROA A;  5HT4 A;  3NZB X;  1DG5 A;  1LUD A;  2B3Z A;  3CSE A;  1DG8 A;  2W3A A;  3UM8 A;  3K74 A;  2ANO A;  3OAF A;  2ITH A;  3EEL A;  5JG0 X;  1LY4 A;  1DYI A;  4EIG A;  3CL9 A;  1HFQ A;  1RX6 A;  2O7P A;  4KEB A;  3FQ0 A;  2INQ A;  1DLS A;  2H2Q A;  7DFR A;  1BZF A;  1RC4 A;  3NRR A;  1DR1 A;  4KJJ A;  3TQB A;  3SR5 X;  4KJK A;  3F0V X;  2ANQ A;  4EJ1 A;  1KLK A;  4ELB A;  4M6L A;  1KMS A;  4P66 A;  3FQC A;  3FQV A;  1RA3 A;  4P68 A;  4FHB A;  3F0S X;  4DPD A;  3SRR X;  3HJ3 A;  4OR7 A;  3FYV X;  3QGT A;  3SRS X;  4CD2 A;  1PDB A;  2CIG A;  3EEJ A;  3QYO A;  3UM5 A;  1AI9 A;  4LAG X;  4QHV A;  1AO8 A;  1E26 A;  3JSU A;  4M6K A;  4H96 A;  1RX5 A;  3QFX A;  1DR5 A;  3DRC A;  3NTZ A;  1BOZ A;  1KMV A;  3EX8 A;  3JTW A;  4LAH X;  3JW5 A;  5HT5 A;  2OBC A;  4X5H A;  2FZH A;  4IXG X;  3FL9 A;  4KYA A;  3K47 A;  3FS6 A;  3CLB A;  3M09 A;  1RX3 A;  3IA4 A;  1IA3 A;  1DHJ A;  4X5G A;  1HFP A;  1SEJ A;  3NZ9 X;  3I3R A;  4KM2 A;  1J3J A;  3IRN A;  4KY4 A;  1VDR A;  4KLX A;  3FY8 X;  1DIS A;  4PST A;  3NXV A;  4PSS A;  2W9S A;  4LEK X;  1JOM A;  4KFJ A;  2W9G A;  4G95 A;  3KJR A;  4KD7 A;  2G6V A;  1IA4 A;  5CCC A;  1OHK A;  3OCH A;  4XEC X;  1U72 A;  4Q67 A;  3NXT A;  3IRM A;  3QYL A;  4PSY A;  1PD8 A;  1RX4 A;  4NX7 A;  4XT7 A;  1M78 A;  4XT8 A;  2CD2 A;  2W9H A;  3FQZ A;  2DRC A;  4TU5 X;  1DYH A;  3NXR A;  2FZJ A;  5HPB A;  3F0U X;  4OSG A;  1LY3 A;  1DYJ A;  3DG8 A;  3QLW A;  4ELE A;  4LAE X;  4XT4 A;  3DAT A;  2P4G A;  1RB2 A;  5DXV A;  3GHV A;  3UM6 A;  3SA2 A;  1DR2 A;  1DLR A;  4M6J A;  4Q6A A;  1YHO A;  3S3V A;  3DL5 A;  3NZ6 X;  1DDR A;  3DAU A;  2BLB A;  1DRE A;  3DGA A;  5JA3 A;  1MVS A;  5U26 A;  4ECK A;  4GH8 A;  5FDA A;  4KY8 A;  3DFR A;  2GD9 A;  3ZPC A;  5HSR A;  2LF1 A;  3K45 A;  2W3B A;  1DG7 A;  3QL0 A;  5ECC A;  3FRB X;  3N0H A;  4RGC A;  5E8Q A;  2W3V A;  1DHF A;  2JYB A;  3SAI A;  2W3W A;  3GI2 A;  5EAJ A;  1DHI A;  1RE7 A;  3JWM A;  3D80 A;  3JW3 A;  4IXE D;  2XW7 A;  3TQ9 A;  4XT5 A;  4KL9 A;  3NXY A;  3L3R A;  1RA1 A;  2C2S A;  1RA9 A;  3F91 A;  4IXF X;  1M79 A;  3KY8 A;  4EIZ A;  3QLS A;  4H98 A;  4HA9 A;  3NZA X;  3FRE X;  3RG9 A;  3SQY X;  4KBN A;  2ZZA A;  3SRW X;  1DAJ A;  3QG2 A;  4HOF A;  1DDS A;  8DFR A;  1JOL A;  1DRH A;  4ELG A;  4FGH A;  3K2H A;  4EIL A;  5CC9 A;  5HVB A;  4P3R A;  1VJ3 A;  4PDJ A;  4QI9 A;  1J3K A;  4M7V A;  3FYW X;  2C2T A;  3SH2 A;  4H95 A;  4P3Q A;  1OHJ A;  3FRD X;  1IA1 A;  1IA2 A;  3JWK A;  2OIP A;  4HOG A;  2AZN A;  3RO9 A;  3JWF A;  3LG4 A;  4QJC A;  4KM0 A;  3S7A A;  1CZ3 A;  3I8A X;  1J3I A;  5DFR A;  2KGK A;  4HA7 A;  3KGY A;  3F8Y A;  5HVE A;  4PTJ A;  2D5N A;  3GYF A;  4PTH A;  3FRA X;  4XRB A;  4KAK A;  3IX9 A;  4X5I A;  1RG7 A;  5U27 A;  6DFR A;  3Q1H A;  2HM9 A;  1RH3 A;  3TQ8 A;  4HOE A;  1S3W A;  3KFY A;  3KJS A;  5HUI A;  3SRQ X;  4I1N A;  3FY9 X;  1DYR A;  1ZDR A;  1HFR A;  2HQP A;  3M08 A;  4FGG A;  1CD2 A;  2L28 A;  3F0X X;  4QLE A;  1RF7 A;  3EEM A;  3IRO A;  1DR3 A;  2FZI A;  4M2X A;  4DFR A;  4XE6 X;  5HQZ A;  3QLX A;  3ZPG A;  2BL9 A;  1JUV A;  4ELF A;  1RX1 A;  3FRF X;  3CD2 A;  1DRF A;  3QLZ A;  1DR6 A;  4I13 A;  1S3Y A;  5ECX A;  1U70 A;  3SGY A;  1TDR A;  3QL3 A;  3NXX A;  1D1G A;  3FQF A;  3S9U A;  1AOE A;  1M7A A;  3EEK A;  1QZF A;  4NX6 A;  1DR7 A;  4DDR A;  4G8Z X;  5HSU A;  3TD8 A;  3FL8 A;  4QJZ D;  4ELH A;  1RA8 A;  3HBB A;  2QK8 A;  2W3M A;  3D84 X;  3NXO A;  5HF2 X;  4DPH A;  4KJL A;  3TQA A;  3NZC X;  1MVT A;  4QLG A;  5HF0 X;  3IA5 A;  1PD9 A;  1DF7 A;  3INV A; 
#chains in the Genus database with same CATH homology
 1U71 A;  4KNE A;  4DP3 A;  3QLY A;  1DRA A;  1RD7 A;  4G3M A;  3GHW A;  4Q0D A;  3F0Q X;  1RX7 A;  1RX9 A;  1DRB A;  1S3U A;  1RB3 A;  3SRU X;  3GHC A;  5HQY A;  2BLC A;  3FQO A;  3E0B A;  3NU0 A;  3R33 A;  2DHF A;  3VCO A;  1S3V A;  3EIG A;  3F8Z A;  3JVX A;  2D0K A;  4XT6 A;  4M7U A;  3JWC A;  1DR4 A;  2BLA A;  5HI6 A;  1RA2 A;  3NZD A;  4H97 A;  3QLR A;  1RX2 A;  3F0B X;  3SA1 A;  4X5J A;  3DL6 A;  4X5F A;  2HXV A;  4Q0E A;  4QLF A;  1RX8 A;  1DIU A;  2W9T A;  3ROA A;  5HT4 A;  3NZB X;  1DG5 A;  1LUD A;  2B3Z A;  3CSE A;  1DG8 A;  2W3A A;  3UM8 A;  3K74 A;  2ANO A;  3OAF A;  2ITH A;  3EEL A;  5JG0 X;  1LY4 A;  1DYI A;  4EIG A;  3CL9 A;  1HFQ A;  1RX6 A;  2O7P A;  4KEB A;  3FQ0 A;  2INQ A;  1DLS A;  2H2Q A;  7DFR A;  1BZF A;  1RC4 A;  3NRR A;  1DR1 A;  4KJJ A;  3TQB A;  3SR5 X;  4KJK A;  3F0V X;  2ANQ A;  4EJ1 A;  1KLK A;  4ELB A;  4M6L A;  1KMS A;  4P66 A;  3FQC A;  3FQV A;  1RA3 A;  4P68 A;  4FHB A;  3F0S X;  4DPD A;  3SRR X;  3HJ3 A;  4OR7 A;  3FYV X;  3QGT A;  3SRS X;  4CD2 A;  1PDB A;  2CIG A;  3EEJ A;  3QYO A;  3UM5 A;  1AI9 A;  4LAG X;  4QHV A;  1AO8 A;  1E26 A;  3JSU A;  4M6K A;  4H96 A;  1RX5 A;  3QFX A;  1DR5 A;  3DRC A;  3NTZ A;  1BOZ A;  1KMV A;  3EX8 A;  3JTW A;  4LAH X;  3JW5 A;  5HT5 A;  2OBC A;  4X5H A;  2FZH A;  4IXG X;  3FL9 A;  4KYA A;  3K47 A;  3FS6 A;  3CLB A;  3M09 A;  1RX3 A;  3IA4 A;  1IA3 A;  1DHJ A;  4X5G A;  1HFP A;  1SEJ A;  3NZ9 X;  3I3R A;  4KM2 A;  1J3J A;  3IRN A;  4KY4 A;  1VDR A;  4KLX A;  3FY8 X;  1DIS A;  4PST A;  3NXV A;  4PSS A;  2W9S A;  4LEK X;  1JOM A;  4KFJ A;  2W9G A;  4G95 A;  3KJR A;  4KD7 A;  2G6V A;  1IA4 A;  5CCC A;  1OHK A;  3OCH A;  4XEC X;  1U72 A;  4Q67 A;  3NXT A;  3IRM A;  3QYL A;  4PSY A;  1PD8 A;  1RX4 A;  4NX7 A;  4XT7 A;  1M78 A;  4XT8 A;  2CD2 A;  2W9H A;  3FQZ A;  2DRC A;  4TU5 X;  1DYH A;  3NXR A;  2FZJ A;  5HPB A;  3F0U X;  4OSG A;  1LY3 A;  1DYJ A;  3DG8 A;  3QLW A;  4ELE A;  4LAE X;  4XT4 A;  3DAT A;  2P4G A;  1RB2 A;  5DXV A;  3GHV A;  3UM6 A;  3SA2 A;  1DR2 A;  1DLR A;  4M6J A;  4Q6A A;  1YHO A;  3S3V A;  3DL5 A;  3NZ6 X;  1DDR A;  3DAU A;  2BLB A;  1DRE A;  3DGA A;  5JA3 A;  1MVS A;  5U26 A;  4ECK A;  4GH8 A;  5FDA A;  4KY8 A;  3DFR A;  2GD9 A;  3ZPC A;  5HSR A;  2LF1 A;  3K45 A;  2W3B A;  1DG7 A;  3QL0 A;  5ECC A;  3FRB X;  3N0H A;  4RGC A;  5E8Q A;  2W3V A;  1DHF A;  2JYB A;  3SAI A;  2W3W A;  3GI2 A;  5EAJ A;  1DHI A;  1RE7 A;  3JWM A;  3D80 A;  3JW3 A;  4IXE D;  2XW7 A;  3TQ9 A;  4XT5 A;  4KL9 A;  3NXY A;  3L3R A;  1RA1 A;  2C2S A;  1RA9 A;  3F91 A;  4IXF X;  1M79 A;  3KY8 A;  4EIZ A;  3QLS A;  4H98 A;  4HA9 A;  3NZA X;  3FRE X;  3RG9 A;  3SQY X;  4KBN A;  2ZZA A;  3SRW X;  1DAJ A;  3QG2 A;  4HOF A;  1DDS A;  8DFR A;  1JOL A;  1DRH A;  4ELG A;  4FGH A;  3K2H A;  4EIL A;  5CC9 A;  5HVB A;  4P3R A;  1VJ3 A;  4PDJ A;  4QI9 A;  1J3K A;  4M7V A;  3FYW X;  2C2T A;  3SH2 A;  4H95 A;  4P3Q A;  1OHJ A;  3FRD X;  1IA1 A;  1IA2 A;  3JWK A;  2OIP A;  4HOG A;  2AZN A;  3RO9 A;  3JWF A;  3LG4 A;  4QJC A;  4KM0 A;  3S7A A;  1CZ3 A;  3I8A X;  1J3I A;  5DFR A;  2KGK A;  4HA7 A;  3KGY A;  3F8Y A;  5HVE A;  4PTJ A;  2D5N A;  3GYF A;  4PTH A;  3FRA X;  4XRB A;  4KAK A;  3IX9 A;  4X5I A;  1RG7 A;  5U27 A;  6DFR A;  3Q1H A;  2HM9 A;  1RH3 A;  3TQ8 A;  4HOE A;  1S3W A;  3KFY A;  3KJS A;  5HUI A;  3SRQ X;  4I1N A;  3FY9 X;  1DYR A;  1ZDR A;  1HFR A;  2HQP A;  3M08 A;  4FGG A;  1CD2 A;  2L28 A;  3F0X X;  4QLE A;  1RF7 A;  3EEM A;  3IRO A;  1DR3 A;  2FZI A;  4M2X A;  4DFR A;  4XE6 X;  5HQZ A;  3QLX A;  3ZPG A;  2BL9 A;  1JUV A;  4ELF A;  1RX1 A;  3FRF X;  3CD2 A;  1DRF A;  3QLZ A;  1DR6 A;  4I13 A;  1S3Y A;  5ECX A;  1U70 A;  3SGY A;  1TDR A;  3QL3 A;  3NXX A;  1D1G A;  3FQF A;  3S9U A;  1AOE A;  1M7A A;  3EEK A;  1QZF A;  4NX6 A;  1DR7 A;  4DDR A;  4G8Z X;  5HSU A;  3TD8 A;  3FL8 A;  4QJZ D;  4ELH A;  1RA8 A;  3HBB A;  2QK8 A;  2W3M A;  3D84 X;  3NXO A;  5HF2 X;  4DPH A;  4KJL A;  3TQA A;  3NZC X;  1MVT A;  4QLG A;  5HF0 X;  3IA5 A;  1PD9 A;  1DF7 A;  3INV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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