3F0VX

Staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Complexes of Wildtype and Mutant MRSA DHFR Reveal Interactions for Lead Design
rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2008-10-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3f0vX00
3DG8A 3GHWA 3UM5A 1HFRA 5U27A 3SRWX 3GYFA 1DG8A 5JG0X 2ANOA 4G8ZX 2G6VA 2DHFA 4PDJA 5DXVA 3TD8A 1IA4A 2H2QA 3CLBA 1RB3A 4ELBA 1DISA 3SAIA 4XT5A 4Q0DA 3SRRX 4GH8A 3JSUA 3DL6A 2W3MA 4H97A 2D5NA 3CL9A 1RA3A 1BOZA 4Q6AA 4PTHA 4KFJA 3QLSA 3FY8X 3SRQX 2W9GA 3SRUX 3M09A 1RX1A 3NXTA 4H98A 2W3BA 5HF2X 3F0BX 4LAEX 3DGAA 3DATA 1JOMA 3E0BA 3FREX 3NZCX 1DLSA 2AZNA 5EAJA 1S3VA 4H96A 3F0UX 2O7PA 1CD2A 3FQOA 4M6JA 3K2HA 1IA3A 3SA1A 3QLZA 1PD8A 4OR7A 1KLKA 1DR6A 1BZFA 3FYVX 3JW5A 5JA3A 3S9UA 4NX6A 5HQYA 1TDRA 1HFPA 5HUIA 4DPDA 5U26A 3JWKA 2W9TA 5HT5A 3UM6A 3NXXA 3GHVA 3QFXA 4X5IA 1RX7A 3Q1HA 3EX8A 1U72A 3EEKA 4EILA 3F0XX 1DR3A 4EJ1A 3CSEA 2XW7A 4IXGX 1RG7A 1DREA 3TQAA 5HSUA 1DHIA 1DF7A 1DHFA 4LAHX 2CD2A 3IA5A 3EEJA 1LY4A 4P3QA 3SH2A 2ANQA 4M2XA 2OIPA 1DG5A 1S3YA 2QK8A 3S7AA 3IA4A 1RD7A 1RX5A 3GHCA 3R33A 3TQ8A 1E26A 4DDRA 3SQYX 3FS6A 3F8ZA 4LAGX 3NZDA 3NZAX 4TU5X 3NZ6X 3INVA 1RA1A 3KY8A 2LF1A 3SGYA 4DFRA 4QJZD 4KAKA 4ELFA 4XT6A 3NXYA 1MVTA 4KY8A 4I13A 2CIGA 4X5FA 5DFRA 4QLEA 4KYAA 4KY4A 1SEJA 3EIGA 1VDRA 4ELHA 5HI6A 3JWCA 4I1NA 1DR7A 3KJRA 3QYLA 3ZPGA 1RX6A 3QG2A 7DFRA 5ECCA 3QL0A 2W9HA 4QI9A 1D1GA 4P3RA 1RB2A 1OHJA 5ECXA 4DP3A 1RX8A 4G3MA 4XE6X 3F91A 2W3WA 4QLGA 4XT8A 3JVXA 4HA9A 2HXVA 4M6LA 5FDAA 1RA8A 4LEKX 4ELGA 1IA2A 3JWMA 1U70A 4XECX 3QLYA 1RX3A 3IX9A 1DRFA 3UM8A 4XT7A 4Q67A 5HF0X 3VCOA 1S3WA 3QLRA 2BLCA 1DRBA 3EEMA 3L3RA 3KFYA 2ITHA 2OBCA 1JUVA 3FQ0A 1ZDRA 3GI2A 4KEBA 4DPHA 3F8YA 2FZJA 2BL9A 3NU0A 4PTJA 1CZ3A 1MVSA 4X5GA 3FL9A 4QLFA 2HQPA 4NX7A 4PSYA 4HOGA 3SRSX 2C2SA 3DAUA 1PDBA 3D84X 3QGTA 3NXVA 1DYJA 4KJKA 2HM9A 3DL5A 1HFQA 1LUDA 3DFRA 1RE7A 4P66A 3ZPCA 4XT4A 4FGGA 1AI9A 1DYRA 3M08A 3FRAX 3FL8A 3K47A 3NZBX 4FHBA 1J3IA 3HBBA 3TQ9A 3JTWA 3NXRA 3SA2A 3F0QX 3OCHA 4G95A 3RG9A 1QZFA 3NTZA 4Q0EA 1DRAA 1KMVA 1YHOA 2L28A 3FRFX 4KNEA 1RA2A 3K74A 3TQBA 4KBNA 1VJ3A 4CD2A 4PSSA 3OAFA 4QHVA 1RA9A 1DDRA 4ELEA 1PD9A 1DLRA 2INQA 1J3KA 1DAJA 2JYBA 3F0VX 3I8AX 4KD7A 1M78A 3K45A 3SR5X 3S3VA 4RGCA 3IRMA 1DYHA 3NRRA 1S3UA 1KMSA 3FYWX 3QLXA 1DIUA 5HT4A 3D80A 3QYOA 1J3JA 5HQZA 3NXOA 1RH3A 3CD2A 2C2TA 3JWFA 4ECKA 4QJCA 8DFRA 4OSGA 3FQZA 4IXED 2DRCA 1LY3A 3KGYA 3FY9X 1AO8A 6DFRA 5HPBA 5CC9A 2B3ZA 3JW3A 4M7VA 2FZIA 1DR5A 4HOEA 4KJLA 2KGKA 3F0SX 3RO9A 4HOFA 1OHKA 1IA1A 2GD9A 1M7AA 1RC4A 4IXFX 1M79A 4EIGA 5CCCA 4KM2A 4KLXA 1DR1A 3HJ3A 4FGHA 1DDSA 3NZ9X 1DHJA 4X5JA 3DRCA 3N0HA 4M6KA 1DYIA 1RF7A 3I3RA 3QLWA 3FQCA 2BLBA 1DRHA 4H95A 4PSTA 1U71A 1JOLA 4KJJA 1RX9A 4KL9A 2D0KA 3IROA 4HA7A 2P4GA 3FQFA 5HVEA 4EIZA 5HSRA 5E8QA 3FQVA 3ROAA 3FRDX 2W3AA 3LG4A 1DR4A 3FRBX 2W9SA 1DR2A 4XRBA 1RX2A 4KM0A 1AOEA 3QL3A 1DG7A 2FZHA 5HVBA 2W3VA 4M7UA 3IRNA 3EELA 2ZZAA 1RX4A 4X5HA 4P68A 3KJSA 2BLAA
chains in the Genus database with same CATH superfamily
3DG8A 3GHWA 3UM5A 1HFRA 5U27A 3SRWX 3GYFA 1DG8A 5JG0X 2ANOA 4G8ZX 2G6VA 2DHFA 4PDJA 5DXVA 3TD8A 1IA4A 2H2QA 3CLBA 1RB3A 4ELBA 1DISA 3SAIA 4XT5A 4Q0DA 3SRRX 4GH8A 3JSUA 3DL6A 2W3MA 4H97A 2D5NA 3CL9A 1RA3A 1BOZA 4Q6AA 4PTHA 4KFJA 3QLSA 3FY8X 3SRQX 2W9GA 3SRUX 3M09A 1RX1A 3NXTA 4H98A 2W3BA 5HF2X 3F0BX 4LAEX 3DGAA 3DATA 1JOMA 3E0BA 3FREX 3NZCX 1DLSA 2AZNA 5EAJA 1S3VA 4H96A 3F0UX 2O7PA 1CD2A 3FQOA 4M6JA 3K2HA 1IA3A 3SA1A 3QLZA 1PD8A 4OR7A 1KLKA 1DR6A 1BZFA 3FYVX 3JW5A 5JA3A 3S9UA 4NX6A 5HQYA 1TDRA 1HFPA 5HUIA 4DPDA 5U26A 3JWKA 2W9TA 5HT5A 3UM6A 3NXXA 3GHVA 3QFXA 4X5IA 1RX7A 3Q1HA 3EX8A 1U72A 3EEKA 4EILA 3F0XX 1DR3A 4EJ1A 3CSEA 2XW7A 4IXGX 1RG7A 1DREA 3TQAA 5HSUA 1DHIA 1DF7A 1DHFA 4LAHX 2CD2A 3IA5A 3EEJA 1LY4A 4P3QA 3SH2A 2ANQA 4M2XA 2OIPA 1DG5A 1S3YA 2QK8A 3S7AA 3IA4A 1RD7A 1RX5A 3GHCA 3R33A 3TQ8A 1E26A 4DDRA 3SQYX 3FS6A 3F8ZA 4LAGX 3NZDA 3NZAX 4TU5X 3NZ6X 3INVA 1RA1A 3KY8A 2LF1A 3SGYA 4DFRA 4QJZD 4KAKA 4ELFA 4XT6A 3NXYA 1MVTA 4KY8A 4I13A 2CIGA 4X5FA 5DFRA 4QLEA 4KYAA 4KY4A 1SEJA 3EIGA 1VDRA 4ELHA 5HI6A 3JWCA 4I1NA 1DR7A 3KJRA 3QYLA 3ZPGA 1RX6A 3QG2A 7DFRA 5ECCA 3QL0A 2W9HA 4QI9A 1D1GA 4P3RA 1RB2A 1OHJA 5ECXA 4DP3A 1RX8A 4G3MA 4XE6X 3F91A 2W3WA 4QLGA 4XT8A 3JVXA 4HA9A 2HXVA 4M6LA 5FDAA 1RA8A 4LEKX 4ELGA 1IA2A 3JWMA 1U70A 4XECX 3QLYA 1RX3A 3IX9A 1DRFA 3UM8A 4XT7A 4Q67A 5HF0X 3VCOA 1S3WA 3QLRA 2BLCA 1DRBA 3EEMA 3L3RA 3KFYA 2ITHA 2OBCA 1JUVA 3FQ0A 1ZDRA 3GI2A 4KEBA 4DPHA 3F8YA 2FZJA 2BL9A 3NU0A 4PTJA 1CZ3A 1MVSA 4X5GA 3FL9A 4QLFA 2HQPA 4NX7A 4PSYA 4HOGA 3SRSX 2C2SA 3DAUA 1PDBA 3D84X 3QGTA 3NXVA 1DYJA 4KJKA 2HM9A 3DL5A 1HFQA 1LUDA 3DFRA 1RE7A 4P66A 3ZPCA 4XT4A 4FGGA 1AI9A 1DYRA 3M08A 3FRAX 3FL8A 3K47A 3NZBX 4FHBA 1J3IA 3HBBA 3TQ9A 3JTWA 3NXRA 3SA2A 3F0QX 3OCHA 4G95A 3RG9A 1QZFA 3NTZA 4Q0EA 1DRAA 1KMVA 1YHOA 2L28A 3FRFX 4KNEA 1RA2A 3K74A 3TQBA 4KBNA 1VJ3A 4CD2A 4PSSA 3OAFA 4QHVA 1RA9A 1DDRA 4ELEA 1PD9A 1DLRA 2INQA 1J3KA 1DAJA 2JYBA 3F0VX 3I8AX 4KD7A 1M78A 3K45A 3SR5X 3S3VA 4RGCA 3IRMA 1DYHA 3NRRA 1S3UA 1KMSA 3FYWX 3QLXA 1DIUA 5HT4A 3D80A 3QYOA 1J3JA 5HQZA 3NXOA 1RH3A 3CD2A 2C2TA 3JWFA 4ECKA 4QJCA 8DFRA 4OSGA 3FQZA 4IXED 2DRCA 1LY3A 3KGYA 3FY9X 1AO8A 6DFRA 5HPBA 5CC9A 2B3ZA 3JW3A 4M7VA 2FZIA 1DR5A 4HOEA 4KJLA 2KGKA 3F0SX 3RO9A 4HOFA 1OHKA 1IA1A 2GD9A 1M7AA 1RC4A 4IXFX 1M79A 4EIGA 5CCCA 4KM2A 4KLXA 1DR1A 3HJ3A 4FGHA 1DDSA 3NZ9X 1DHJA 4X5JA 3DRCA 3N0HA 4M6KA 1DYIA 1RF7A 3I3RA 3QLWA 3FQCA 2BLBA 1DRHA 4H95A 4PSTA 1U71A 1JOLA 4KJJA 1RX9A 4KL9A 2D0KA 3IROA 4HA7A 2P4GA 3FQFA 5HVEA 4EIZA 5HSRA 5E8QA 3FQVA 3ROAA 3FRDX 2W3AA 3LG4A 1DR4A 3FRBX 2W9SA 1DR2A 4XRBA 1RX2A 4KM0A 1AOEA 3QL3A 1DG7A 2FZHA 5HVBA 2W3VA 4M7UA 3IRNA 3EELA 2ZZAA 1RX4A 4X5HA 4P68A 3KJSA 2BLAA
chains in the Genus database with same CATH topology
3DG8A 3GHWA 3UM5A 1HFRA 5U27A 3SRWX 3GYFA 1DG8A 5JG0X 2ANOA 4G8ZX 2G6VA 2DHFA 4PDJA 5DXVA 3TD8A 1IA4A 2H2QA 3CLBA 1RB3A 4ELBA 1DISA 3SAIA 4XT5A 4Q0DA 3SRRX 4GH8A 3JSUA 3DL6A 2W3MA 4H97A 2D5NA 3CL9A 1RA3A 1BOZA 4Q6AA 4PTHA 4KFJA 3QLSA 3FY8X 3SRQX 2W9GA 3SRUX 3M09A 1RX1A 3NXTA 4H98A 2W3BA 5HF2X 3F0BX 4LAEX 3DGAA 3DATA 1JOMA 3E0BA 3FREX 3NZCX 1DLSA 2AZNA 5EAJA 1S3VA 4H96A 3F0UX 2O7PA 1CD2A 3FQOA 4M6JA 3K2HA 1IA3A 3SA1A 3QLZA 1PD8A 4OR7A 1KLKA 1DR6A 1BZFA 3FYVX 3JW5A 5JA3A 3S9UA 4NX6A 5HQYA 1TDRA 1HFPA 5HUIA 4DPDA 5U26A 3JWKA 2W9TA 5HT5A 3UM6A 3NXXA 3GHVA 3QFXA 4X5IA 1RX7A 3Q1HA 3EX8A 1U72A 3EEKA 4EILA 3F0XX 1DR3A 4EJ1A 3CSEA 2XW7A 4IXGX 1RG7A 1DREA 3TQAA 5HSUA 1DHIA 1DF7A 1DHFA 4LAHX 2CD2A 3IA5A 3EEJA 1LY4A 4P3QA 3SH2A 2ANQA 4M2XA 2OIPA 1DG5A 1S3YA 2QK8A 3S7AA 3IA4A 1RD7A 1RX5A 3GHCA 3R33A 3TQ8A 1E26A 4DDRA 3SQYX 3FS6A 3F8ZA 4LAGX 3NZDA 3NZAX 4TU5X 3NZ6X 3INVA 1RA1A 3KY8A 2LF1A 3SGYA 4DFRA 4QJZD 4KAKA 4ELFA 4XT6A 3NXYA 1MVTA 4KY8A 4I13A 2CIGA 4X5FA 5DFRA 4QLEA 4KYAA 4KY4A 1SEJA 3EIGA 1VDRA 4ELHA 5HI6A 3JWCA 4I1NA 1DR7A 3KJRA 3QYLA 3ZPGA 1RX6A 3QG2A 7DFRA 5ECCA 3QL0A 2W9HA 4QI9A 1D1GA 4P3RA 1RB2A 1OHJA 5ECXA 4DP3A 1RX8A 4G3MA 4XE6X 3F91A 2W3WA 4QLGA 4XT8A 3JVXA 4HA9A 2HXVA 4M6LA 5FDAA 1RA8A 4LEKX 4ELGA 1IA2A 3JWMA 1U70A 4XECX 3QLYA 1RX3A 3IX9A 1DRFA 3UM8A 4XT7A 4Q67A 5HF0X 3VCOA 1S3WA 3QLRA 2BLCA 1DRBA 3EEMA 3L3RA 3KFYA 2ITHA 2OBCA 1JUVA 3FQ0A 1ZDRA 3GI2A 4KEBA 4DPHA 3F8YA 2FZJA 2BL9A 3NU0A 4PTJA 1CZ3A 1MVSA 4X5GA 3FL9A 4QLFA 2HQPA 4NX7A 4PSYA 4HOGA 3SRSX 2C2SA 3DAUA 1PDBA 3D84X 3QGTA 3NXVA 1DYJA 4KJKA 2HM9A 3DL5A 1HFQA 1LUDA 3DFRA 1RE7A 4P66A 3ZPCA 4XT4A 4FGGA 1AI9A 1DYRA 3M08A 3FRAX 3FL8A 3K47A 3NZBX 4FHBA 1J3IA 3HBBA 3TQ9A 3JTWA 3NXRA 3SA2A 3F0QX 3OCHA 4G95A 3RG9A 1QZFA 3NTZA 4Q0EA 1DRAA 1KMVA 1YHOA 2L28A 3FRFX 4KNEA 1RA2A 3K74A 3TQBA 4KBNA 1VJ3A 4CD2A 4PSSA 3OAFA 4QHVA 1RA9A 1DDRA 4ELEA 1PD9A 1DLRA 2INQA 1J3KA 1DAJA 2JYBA 3F0VX 3I8AX 4KD7A 1M78A 3K45A 3SR5X 3S3VA 4RGCA 3IRMA 1DYHA 3NRRA 1S3UA 1KMSA 3FYWX 3QLXA 1DIUA 5HT4A 3D80A 3QYOA 1J3JA 5HQZA 3NXOA 1RH3A 3CD2A 2C2TA 3JWFA 4ECKA 4QJCA 8DFRA 4OSGA 3FQZA 4IXED 2DRCA 1LY3A 3KGYA 3FY9X 1AO8A 6DFRA 5HPBA 5CC9A 2B3ZA 3JW3A 4M7VA 2FZIA 1DR5A 4HOEA 4KJLA 2KGKA 3F0SX 3RO9A 4HOFA 1OHKA 1IA1A 2GD9A 1M7AA 1RC4A 4IXFX 1M79A 4EIGA 5CCCA 4KM2A 4KLXA 1DR1A 3HJ3A 4FGHA 1DDSA 3NZ9X 1DHJA 4X5JA 3DRCA 3N0HA 4M6KA 1DYIA 1RF7A 3I3RA 3QLWA 3FQCA 2BLBA 1DRHA 4H95A 4PSTA 1U71A 1JOLA 4KJJA 1RX9A 4KL9A 2D0KA 3IROA 4HA7A 2P4GA 3FQFA 5HVEA 4EIZA 5HSRA 5E8QA 3FQVA 3ROAA 3FRDX 2W3AA 3LG4A 1DR4A 3FRBX 2W9SA 1DR2A 4XRBA 1RX2A 4KM0A 1AOEA 3QL3A 1DG7A 2FZHA 5HVBA 2W3VA 4M7UA 3IRNA 3EELA 2ZZAA 1RX4A 4X5HA 4P68A 3KJSA 2BLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DG8 A;  3GHW A;  3UM5 A;  1HFR A;  5U27 A;  3SRW X;  3GYF A;  1DG8 A;  5JG0 X;  2ANO A;  4G8Z X;  2G6V A;  2DHF A;  4PDJ A;  5DXV A;  3TD8 A;  1IA4 A;  2H2Q A;  3CLB A;  1RB3 A;  4ELB A;  1DIS A;  3SAI A;  4XT5 A;  4Q0D A;  3SRR X;  4GH8 A;  3JSU A;  3DL6 A;  2W3M A;  4H97 A;  2D5N A;  3CL9 A;  1RA3 A;  1BOZ A;  4Q6A A;  4PTH A;  4KFJ A;  3QLS A;  3FY8 X;  3SRQ X;  2W9G A;  3SRU X;  3M09 A;  1RX1 A;  3NXT A;  4H98 A;  2W3B A;  5HF2 X;  3F0B X;  4LAE X;  3DGA A;  3DAT A;  1JOM A;  3E0B A;  3FRE X;  3NZC X;  1DLS A;  2AZN A;  5EAJ A;  1S3V A;  4H96 A;  3F0U X;  2O7P A;  1CD2 A;  3FQO A;  4M6J A;  3K2H A;  1IA3 A;  3SA1 A;  3QLZ A;  1PD8 A;  4OR7 A;  1KLK A;  1DR6 A;  1BZF A;  3FYV X;  3JW5 A;  5JA3 A;  3S9U A;  4NX6 A;  5HQY A;  1TDR A;  1HFP A;  5HUI A;  4DPD A;  5U26 A;  3JWK A;  2W9T A;  5HT5 A;  3UM6 A;  3NXX A;  3GHV A;  3QFX A;  4X5I A;  1RX7 A;  3Q1H A;  3EX8 A;  1U72 A;  3EEK A;  4EIL A;  3F0X X;  1DR3 A;  4EJ1 A;  3CSE A;  2XW7 A;  4IXG X;  1RG7 A;  1DRE A;  3TQA A;  5HSU A;  1DHI A;  1DF7 A;  1DHF A;  4LAH X;  2CD2 A;  3IA5 A;  3EEJ A;  1LY4 A;  4P3Q A;  3SH2 A;  2ANQ A;  4M2X A;  2OIP A;  1DG5 A;  1S3Y A;  2QK8 A;  3S7A A;  3IA4 A;  1RD7 A;  1RX5 A;  3GHC A;  3R33 A;  3TQ8 A;  1E26 A;  4DDR A;  3SQY X;  3FS6 A;  3F8Z A;  4LAG X;  3NZD A;  3NZA X;  4TU5 X;  3NZ6 X;  3INV A;  1RA1 A;  3KY8 A;  2LF1 A;  3SGY A;  4DFR A;  4QJZ D;  4KAK A;  4ELF A;  4XT6 A;  3NXY A;  1MVT A;  4KY8 A;  4I13 A;  2CIG A;  4X5F A;  5DFR A;  4QLE A;  4KYA A;  4KY4 A;  1SEJ A;  3EIG A;  1VDR A;  4ELH A;  5HI6 A;  3JWC A;  4I1N A;  1DR7 A;  3KJR A;  3QYL A;  3ZPG A;  1RX6 A;  3QG2 A;  7DFR A;  5ECC A;  3QL0 A;  2W9H A;  4QI9 A;  1D1G A;  4P3R A;  1RB2 A;  1OHJ A;  5ECX A;  4DP3 A;  1RX8 A;  4G3M A;  4XE6 X;  3F91 A;  2W3W A;  4QLG A;  4XT8 A;  3JVX A;  4HA9 A;  2HXV A;  4M6L A;  5FDA A;  1RA8 A;  4LEK X;  4ELG A;  1IA2 A;  3JWM A;  1U70 A;  4XEC X;  3QLY A;  1RX3 A;  3IX9 A;  1DRF A;  3UM8 A;  4XT7 A;  4Q67 A;  5HF0 X;  3VCO A;  1S3W A;  3QLR A;  2BLC A;  1DRB A;  3EEM A;  3L3R A;  3KFY A;  2ITH A;  2OBC A;  1JUV A;  3FQ0 A;  1ZDR A;  3GI2 A;  4KEB A;  4DPH A;  3F8Y A;  2FZJ A;  2BL9 A;  3NU0 A;  4PTJ A;  1CZ3 A;  1MVS A;  4X5G A;  3FL9 A;  4QLF A;  2HQP A;  4NX7 A;  4PSY A;  4HOG A;  3SRS X;  2C2S A;  3DAU A;  1PDB A;  3D84 X;  3QGT A;  3NXV A;  1DYJ A;  4KJK A;  2HM9 A;  3DL5 A;  1HFQ A;  1LUD A;  3DFR A;  1RE7 A;  4P66 A;  3ZPC A;  4XT4 A;  4FGG A;  1AI9 A;  1DYR A;  3M08 A;  3FRA X;  3FL8 A;  3K47 A;  3NZB X;  4FHB A;  1J3I A;  3HBB A;  3TQ9 A;  3JTW A;  3NXR A;  3SA2 A;  3F0Q X;  3OCH A;  4G95 A;  3RG9 A;  1QZF A;  3NTZ A;  4Q0E A;  1DRA A;  1KMV A;  1YHO A;  2L28 A;  3FRF X;  4KNE A;  1RA2 A;  3K74 A;  3TQB A;  4KBN A;  1VJ3 A;  4CD2 A;  4PSS A;  3OAF A;  4QHV A;  1RA9 A;  1DDR A;  4ELE A;  1PD9 A;  1DLR A;  2INQ A;  1J3K A;  1DAJ A;  2JYB A;  3F0V X;  3I8A X;  4KD7 A;  1M78 A;  3K45 A;  3SR5 X;  3S3V A;  4RGC A;  3IRM A;  1DYH A;  3NRR A;  1S3U A;  1KMS A;  3FYW X;  3QLX A;  1DIU A;  5HT4 A;  3D80 A;  3QYO A;  1J3J A;  5HQZ A;  3NXO A;  1RH3 A;  3CD2 A;  2C2T A;  3JWF A;  4ECK A;  4QJC A;  8DFR A;  4OSG A;  3FQZ A;  4IXE D;  2DRC A;  1LY3 A;  3KGY A;  3FY9 X;  1AO8 A;  6DFR A;  5HPB A;  5CC9 A;  2B3Z A;  3JW3 A;  4M7V A;  2FZI A;  1DR5 A;  4HOE A;  4KJL A;  2KGK A;  3F0S X;  3RO9 A;  4HOF A;  1OHK A;  1IA1 A;  2GD9 A;  1M7A A;  1RC4 A;  4IXF X;  1M79 A;  4EIG A;  5CCC A;  4KM2 A;  4KLX A;  1DR1 A;  3HJ3 A;  4FGH A;  1DDS A;  3NZ9 X;  1DHJ A;  4X5J A;  3DRC A;  3N0H A;  4M6K A;  1DYI A;  1RF7 A;  3I3R A;  3QLW A;  3FQC A;  2BLB A;  1DRH A;  4H95 A;  4PST A;  1U71 A;  1JOL A;  4KJJ A;  1RX9 A;  4KL9 A;  2D0K A;  3IRO A;  4HA7 A;  2P4G A;  3FQF A;  5HVE A;  4EIZ A;  5HSR A;  5E8Q A;  3FQV A;  3ROA A;  3FRD X;  2W3A A;  3LG4 A;  1DR4 A;  3FRB X;  2W9S A;  1DR2 A;  4XRB A;  1RX2 A;  4KM0 A;  1AOE A;  3QL3 A;  1DG7 A;  2FZH A;  5HVB A;  2W3V A;  4M7U A;  3IRN A;  3EEL A;  2ZZA A;  1RX4 A;  4X5H A;  4P68 A;  3KJS A;  2BLA A; 
#chains in the Genus database with same CATH topology
 3DG8 A;  3GHW A;  3UM5 A;  1HFR A;  5U27 A;  3SRW X;  3GYF A;  1DG8 A;  5JG0 X;  2ANO A;  4G8Z X;  2G6V A;  2DHF A;  4PDJ A;  5DXV A;  3TD8 A;  1IA4 A;  2H2Q A;  3CLB A;  1RB3 A;  4ELB A;  1DIS A;  3SAI A;  4XT5 A;  4Q0D A;  3SRR X;  4GH8 A;  3JSU A;  3DL6 A;  2W3M A;  4H97 A;  2D5N A;  3CL9 A;  1RA3 A;  1BOZ A;  4Q6A A;  4PTH A;  4KFJ A;  3QLS A;  3FY8 X;  3SRQ X;  2W9G A;  3SRU X;  3M09 A;  1RX1 A;  3NXT A;  4H98 A;  2W3B A;  5HF2 X;  3F0B X;  4LAE X;  3DGA A;  3DAT A;  1JOM A;  3E0B A;  3FRE X;  3NZC X;  1DLS A;  2AZN A;  5EAJ A;  1S3V A;  4H96 A;  3F0U X;  2O7P A;  1CD2 A;  3FQO A;  4M6J A;  3K2H A;  1IA3 A;  3SA1 A;  3QLZ A;  1PD8 A;  4OR7 A;  1KLK A;  1DR6 A;  1BZF A;  3FYV X;  3JW5 A;  5JA3 A;  3S9U A;  4NX6 A;  5HQY A;  1TDR A;  1HFP A;  5HUI A;  4DPD A;  5U26 A;  3JWK A;  2W9T A;  5HT5 A;  3UM6 A;  3NXX A;  3GHV A;  3QFX A;  4X5I A;  1RX7 A;  3Q1H A;  3EX8 A;  1U72 A;  3EEK A;  4EIL A;  3F0X X;  1DR3 A;  4EJ1 A;  3CSE A;  2XW7 A;  4IXG X;  1RG7 A;  1DRE A;  3TQA A;  5HSU A;  1DHI A;  1DF7 A;  1DHF A;  4LAH X;  2CD2 A;  3IA5 A;  3EEJ A;  1LY4 A;  4P3Q A;  3SH2 A;  2ANQ A;  4M2X A;  2OIP A;  1DG5 A;  1S3Y A;  2QK8 A;  3S7A A;  3IA4 A;  1RD7 A;  1RX5 A;  3GHC A;  3R33 A;  3TQ8 A;  1E26 A;  4DDR A;  3SQY X;  3FS6 A;  3F8Z A;  4LAG X;  3NZD A;  3NZA X;  4TU5 X;  3NZ6 X;  3INV A;  1RA1 A;  3KY8 A;  2LF1 A;  3SGY A;  4DFR A;  4QJZ D;  4KAK A;  4ELF A;  4XT6 A;  3NXY A;  1MVT A;  4KY8 A;  4I13 A;  2CIG A;  4X5F A;  5DFR A;  4QLE A;  4KYA A;  4KY4 A;  1SEJ A;  3EIG A;  1VDR A;  4ELH A;  5HI6 A;  3JWC A;  4I1N A;  1DR7 A;  3KJR A;  3QYL A;  3ZPG A;  1RX6 A;  3QG2 A;  7DFR A;  5ECC A;  3QL0 A;  2W9H A;  4QI9 A;  1D1G A;  4P3R A;  1RB2 A;  1OHJ A;  5ECX A;  4DP3 A;  1RX8 A;  4G3M A;  4XE6 X;  3F91 A;  2W3W A;  4QLG A;  4XT8 A;  3JVX A;  4HA9 A;  2HXV A;  4M6L A;  5FDA A;  1RA8 A;  4LEK X;  4ELG A;  1IA2 A;  3JWM A;  1U70 A;  4XEC X;  3QLY A;  1RX3 A;  3IX9 A;  1DRF A;  3UM8 A;  4XT7 A;  4Q67 A;  5HF0 X;  3VCO A;  1S3W A;  3QLR A;  2BLC A;  1DRB A;  3EEM A;  3L3R A;  3KFY A;  2ITH A;  2OBC A;  1JUV A;  3FQ0 A;  1ZDR A;  3GI2 A;  4KEB A;  4DPH A;  3F8Y A;  2FZJ A;  2BL9 A;  3NU0 A;  4PTJ A;  1CZ3 A;  1MVS A;  4X5G A;  3FL9 A;  4QLF A;  2HQP A;  4NX7 A;  4PSY A;  4HOG A;  3SRS X;  2C2S A;  3DAU A;  1PDB A;  3D84 X;  3QGT A;  3NXV A;  1DYJ A;  4KJK A;  2HM9 A;  3DL5 A;  1HFQ A;  1LUD A;  3DFR A;  1RE7 A;  4P66 A;  3ZPC A;  4XT4 A;  4FGG A;  1AI9 A;  1DYR A;  3M08 A;  3FRA X;  3FL8 A;  3K47 A;  3NZB X;  4FHB A;  1J3I A;  3HBB A;  3TQ9 A;  3JTW A;  3NXR A;  3SA2 A;  3F0Q X;  3OCH A;  4G95 A;  3RG9 A;  1QZF A;  3NTZ A;  4Q0E A;  1DRA A;  1KMV A;  1YHO A;  2L28 A;  3FRF X;  4KNE A;  1RA2 A;  3K74 A;  3TQB A;  4KBN A;  1VJ3 A;  4CD2 A;  4PSS A;  3OAF A;  4QHV A;  1RA9 A;  1DDR A;  4ELE A;  1PD9 A;  1DLR A;  2INQ A;  1J3K A;  1DAJ A;  2JYB A;  3F0V X;  3I8A X;  4KD7 A;  1M78 A;  3K45 A;  3SR5 X;  3S3V A;  4RGC A;  3IRM A;  1DYH A;  3NRR A;  1S3U A;  1KMS A;  3FYW X;  3QLX A;  1DIU A;  5HT4 A;  3D80 A;  3QYO A;  1J3J A;  5HQZ A;  3NXO A;  1RH3 A;  3CD2 A;  2C2T A;  3JWF A;  4ECK A;  4QJC A;  8DFR A;  4OSG A;  3FQZ A;  4IXE D;  2DRC A;  1LY3 A;  3KGY A;  3FY9 X;  1AO8 A;  6DFR A;  5HPB A;  5CC9 A;  2B3Z A;  3JW3 A;  4M7V A;  2FZI A;  1DR5 A;  4HOE A;  4KJL A;  2KGK A;  3F0S X;  3RO9 A;  4HOF A;  1OHK A;  1IA1 A;  2GD9 A;  1M7A A;  1RC4 A;  4IXF X;  1M79 A;  4EIG A;  5CCC A;  4KM2 A;  4KLX A;  1DR1 A;  3HJ3 A;  4FGH A;  1DDS A;  3NZ9 X;  1DHJ A;  4X5J A;  3DRC A;  3N0H A;  4M6K A;  1DYI A;  1RF7 A;  3I3R A;  3QLW A;  3FQC A;  2BLB A;  1DRH A;  4H95 A;  4PST A;  1U71 A;  1JOL A;  4KJJ A;  1RX9 A;  4KL9 A;  2D0K A;  3IRO A;  4HA7 A;  2P4G A;  3FQF A;  5HVE A;  4EIZ A;  5HSR A;  5E8Q A;  3FQV A;  3ROA A;  3FRD X;  2W3A A;  3LG4 A;  1DR4 A;  3FRB X;  2W9S A;  1DR2 A;  4XRB A;  1RX2 A;  4KM0 A;  1AOE A;  3QL3 A;  1DG7 A;  2FZH A;  5HVB A;  2W3V A;  4M7U A;  3IRN A;  3EEL A;  2ZZA A;  1RX4 A;  4X5H A;  4P68 A;  3KJS A;  2BLA A; 
#chains in the Genus database with same CATH homology
 3DG8 A;  3GHW A;  3UM5 A;  1HFR A;  5U27 A;  3SRW X;  3GYF A;  1DG8 A;  5JG0 X;  2ANO A;  4G8Z X;  2G6V A;  2DHF A;  4PDJ A;  5DXV A;  3TD8 A;  1IA4 A;  2H2Q A;  3CLB A;  1RB3 A;  4ELB A;  1DIS A;  3SAI A;  4XT5 A;  4Q0D A;  3SRR X;  4GH8 A;  3JSU A;  3DL6 A;  2W3M A;  4H97 A;  2D5N A;  3CL9 A;  1RA3 A;  1BOZ A;  4Q6A A;  4PTH A;  4KFJ A;  3QLS A;  3FY8 X;  3SRQ X;  2W9G A;  3SRU X;  3M09 A;  1RX1 A;  3NXT A;  4H98 A;  2W3B A;  5HF2 X;  3F0B X;  4LAE X;  3DGA A;  3DAT A;  1JOM A;  3E0B A;  3FRE X;  3NZC X;  1DLS A;  2AZN A;  5EAJ A;  1S3V A;  4H96 A;  3F0U X;  2O7P A;  1CD2 A;  3FQO A;  4M6J A;  3K2H A;  1IA3 A;  3SA1 A;  3QLZ A;  1PD8 A;  4OR7 A;  1KLK A;  1DR6 A;  1BZF A;  3FYV X;  3JW5 A;  5JA3 A;  3S9U A;  4NX6 A;  5HQY A;  1TDR A;  1HFP A;  5HUI A;  4DPD A;  5U26 A;  3JWK A;  2W9T A;  5HT5 A;  3UM6 A;  3NXX A;  3GHV A;  3QFX A;  4X5I A;  1RX7 A;  3Q1H A;  3EX8 A;  1U72 A;  3EEK A;  4EIL A;  3F0X X;  1DR3 A;  4EJ1 A;  3CSE A;  2XW7 A;  4IXG X;  1RG7 A;  1DRE A;  3TQA A;  5HSU A;  1DHI A;  1DF7 A;  1DHF A;  4LAH X;  2CD2 A;  3IA5 A;  3EEJ A;  1LY4 A;  4P3Q A;  3SH2 A;  2ANQ A;  4M2X A;  2OIP A;  1DG5 A;  1S3Y A;  2QK8 A;  3S7A A;  3IA4 A;  1RD7 A;  1RX5 A;  3GHC A;  3R33 A;  3TQ8 A;  1E26 A;  4DDR A;  3SQY X;  3FS6 A;  3F8Z A;  4LAG X;  3NZD A;  3NZA X;  4TU5 X;  3NZ6 X;  3INV A;  1RA1 A;  3KY8 A;  2LF1 A;  3SGY A;  4DFR A;  4QJZ D;  4KAK A;  4ELF A;  4XT6 A;  3NXY A;  1MVT A;  4KY8 A;  4I13 A;  2CIG A;  4X5F A;  5DFR A;  4QLE A;  4KYA A;  4KY4 A;  1SEJ A;  3EIG A;  1VDR A;  4ELH A;  5HI6 A;  3JWC A;  4I1N A;  1DR7 A;  3KJR A;  3QYL A;  3ZPG A;  1RX6 A;  3QG2 A;  7DFR A;  5ECC A;  3QL0 A;  2W9H A;  4QI9 A;  1D1G A;  4P3R A;  1RB2 A;  1OHJ A;  5ECX A;  4DP3 A;  1RX8 A;  4G3M A;  4XE6 X;  3F91 A;  2W3W A;  4QLG A;  4XT8 A;  3JVX A;  4HA9 A;  2HXV A;  4M6L A;  5FDA A;  1RA8 A;  4LEK X;  4ELG A;  1IA2 A;  3JWM A;  1U70 A;  4XEC X;  3QLY A;  1RX3 A;  3IX9 A;  1DRF A;  3UM8 A;  4XT7 A;  4Q67 A;  5HF0 X;  3VCO A;  1S3W A;  3QLR A;  2BLC A;  1DRB A;  3EEM A;  3L3R A;  3KFY A;  2ITH A;  2OBC A;  1JUV A;  3FQ0 A;  1ZDR A;  3GI2 A;  4KEB A;  4DPH A;  3F8Y A;  2FZJ A;  2BL9 A;  3NU0 A;  4PTJ A;  1CZ3 A;  1MVS A;  4X5G A;  3FL9 A;  4QLF A;  2HQP A;  4NX7 A;  4PSY A;  4HOG A;  3SRS X;  2C2S A;  3DAU A;  1PDB A;  3D84 X;  3QGT A;  3NXV A;  1DYJ A;  4KJK A;  2HM9 A;  3DL5 A;  1HFQ A;  1LUD A;  3DFR A;  1RE7 A;  4P66 A;  3ZPC A;  4XT4 A;  4FGG A;  1AI9 A;  1DYR A;  3M08 A;  3FRA X;  3FL8 A;  3K47 A;  3NZB X;  4FHB A;  1J3I A;  3HBB A;  3TQ9 A;  3JTW A;  3NXR A;  3SA2 A;  3F0Q X;  3OCH A;  4G95 A;  3RG9 A;  1QZF A;  3NTZ A;  4Q0E A;  1DRA A;  1KMV A;  1YHO A;  2L28 A;  3FRF X;  4KNE A;  1RA2 A;  3K74 A;  3TQB A;  4KBN A;  1VJ3 A;  4CD2 A;  4PSS A;  3OAF A;  4QHV A;  1RA9 A;  1DDR A;  4ELE A;  1PD9 A;  1DLR A;  2INQ A;  1J3K A;  1DAJ A;  2JYB A;  3F0V X;  3I8A X;  4KD7 A;  1M78 A;  3K45 A;  3SR5 X;  3S3V A;  4RGC A;  3IRM A;  1DYH A;  3NRR A;  1S3U A;  1KMS A;  3FYW X;  3QLX A;  1DIU A;  5HT4 A;  3D80 A;  3QYO A;  1J3J A;  5HQZ A;  3NXO A;  1RH3 A;  3CD2 A;  2C2T A;  3JWF A;  4ECK A;  4QJC A;  8DFR A;  4OSG A;  3FQZ A;  4IXE D;  2DRC A;  1LY3 A;  3KGY A;  3FY9 X;  1AO8 A;  6DFR A;  5HPB A;  5CC9 A;  2B3Z A;  3JW3 A;  4M7V A;  2FZI A;  1DR5 A;  4HOE A;  4KJL A;  2KGK A;  3F0S X;  3RO9 A;  4HOF A;  1OHK A;  1IA1 A;  2GD9 A;  1M7A A;  1RC4 A;  4IXF X;  1M79 A;  4EIG A;  5CCC A;  4KM2 A;  4KLX A;  1DR1 A;  3HJ3 A;  4FGH A;  1DDS A;  3NZ9 X;  1DHJ A;  4X5J A;  3DRC A;  3N0H A;  4M6K A;  1DYI A;  1RF7 A;  3I3R A;  3QLW A;  3FQC A;  2BLB A;  1DRH A;  4H95 A;  4PST A;  1U71 A;  1JOL A;  4KJJ A;  1RX9 A;  4KL9 A;  2D0K A;  3IRO A;  4HA7 A;  2P4G A;  3FQF A;  5HVE A;  4EIZ A;  5HSR A;  5E8Q A;  3FQV A;  3ROA A;  3FRD X;  2W3A A;  3LG4 A;  1DR4 A;  3FRB X;  2W9S A;  1DR2 A;  4XRB A;  1RX2 A;  4KM0 A;  1AOE A;  3QL3 A;  1DG7 A;  2FZH A;  5HVB A;  2W3V A;  4M7U A;  3IRN A;  3EEL A;  2ZZA A;  1RX4 A;  4X5H A;  4P68 A;  3KJS A;  2BLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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