3FQ0A

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (ucp120b)
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 42
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fq0A00
3NXOA 1DDRA 4ELEA 7DFRA 2XW7A 3SRRX 3SR5X 1DR6A 4XT5A 3FQ0A 1S3WA 2B3ZA 1S3UA 3FQOA 3HBBA 1JOMA 1RX2A 1RX5A 3K2HA 1DYHA 4RGCA 3SRSX 3EELA 3FRBX 1DHFA 3FY8X 1IA4A 3CLBA 3VCOA 2KGKA 4FGGA 1TDRA 1AOEA 2C2SA 4G95A 2GD9A 3D84X 3INVA 3RO9A 4Q0DA 3F8YA 4KJKA 4X5IA 3DG8A 4KAKA 1J3JA 4I1NA 3FY9X 3JVXA 1DG7A 2DHFA 3QLYA 2C2TA 4DPDA 2W9HA 3IRMA 1M78A 1HFPA 3JWMA 3QL3A 1RB3A 1PD8A 4H98A 2QK8A 4G8ZX 3NRRA 4QHVA 1IA3A 1J3KA 3NZDA 4KY8A 1PDBA 1DHIA 2CIGA 1YHOA 1RA2A 3UM5A 8DFRA 1RX1A 3KY8A 2W3WA 4IXGX 4DP3A 1M79A 1DRAA 3DFRA 1DYIA 1DR3A 1AI9A 2ANOA 3K74A 1VJ3A 3DL6A 5HI6A 3JW5A 5HT4A 3SRQX 3DRCA 3NU0A 1QZFA 2G6VA 4X5GA 3QGTA 3EX8A 1MVSA 4KLXA 2OIPA 1BOZA 3TD8A 3R33A 1RD7A 4PSYA 4H95A 2W9GA 1DHJA 3GI2A 1DAJA 1RA9A 4OSGA 3RG9A 1SEJA 2W9SA 4XT4A 3DAUA 3SA2A 3M08A 3CL9A 1LUDA 4KJJA 3S7AA 1RF7A 1DF7A 3QL0A 4ELFA 3SA1A 3S9UA 4KD7A 4M2XA 3DGAA 3IX9A 3FQCA 5HT5A 1DR7A 3OAFA 3N0HA 3QLWA 4HOFA 3FQZA 3FL8A 3EEMA 2W9TA 1RX4A 2HQPA 1OHKA 1HFRA 2ZZAA 3NXYA 1RX8A 3SRWX 4ELGA 4KY4A 3FS6A 1HFQA 2CD2A 2H2QA 4P68A 4X5HA 1DRHA 1RC4A 4KBNA 4KEBA 3FL9A 5EAJA 3IRNA 4X5JA 4LEKX 4P3QA 2W3BA 2FZIA 3JSUA 4OR7A 2W3MA 4KYAA 3GHWA 4M6LA 1M7AA 4XECX 6DFRA 3FRFX 3UM6A 3KFYA 3K47A 2D0KA 5HPBA 3SH2A 3M09A 5U26A 4G3MA 4DPHA 3KJSA 4NX6A 1AO8A 1DRFA 4H97A 4Q67A 4XT7A 3JW3A 1KLKA 3NXVA 4EJ1A 1CD2A 1DR1A 2O7PA 3QFXA 5HQZA 4LAHX 3SQYX 5CC9A 2DRCA 5DXVA 1DDSA 1LY4A 3NZCX 3GHVA 4M6JA 4EIGA 5E8QA 2W3VA 3NXXA 1DG8A 1JUVA 4QLGA 1PD9A 3F0BX 1KMVA 2AZNA 3D80A 3FYVX 3FREX 5HSUA 2INQA 3LG4A 4EIZA 3JWFA 4XRBA 2HM9A 1DYJA 2P4GA 4P3RA 1RA1A 3F0SX 3TQAA 5HSRA 4HOGA 3NZ9X 3KJRA 4DFRA 4FGHA 2HXVA 4QJZD 1MVTA 1JOLA 4KL9A 4EILA 3DATA 4Q6AA 4LAEX 3IA4A 3QLRA 3EEJA 5HVBA 4LAGX 3UM8A 3FYWX 4GH8A 4ECKA 3EIGA 1D1GA 4H96A 4CD2A 3FRDX 4DDRA 4HA7A 5HQYA 1ZDRA 3Q1HA 3HJ3A 3NZ6X 1CZ3A 1DR4A 4I13A 3QYOA 4QLEA 1DYRA 3NTZA 4M6KA 5ECCA 1RG7A 3F0UX 1RH3A 4KNEA 4KJLA 3TQ8A 3K45A 3EEKA 3SGYA 4ELHA 4KFJA 1J3IA 3SRUX 4XE6X 3NZAX 5DFRA 4QJCA 1DISA 3I8AX 3ZPCA 3GHCA 3OCHA 3L3RA 5ECXA 3E0BA 4PTHA 3DL5A 5HF0X 1RX6A 3QLSA 1RA3A 3QLXA 3F0QX 2OBCA 4M7VA 3TQBA 3I3RA 1IA2A 5U27A 3JWKA 1OHJA 2W3AA 1BZFA 2D5NA 2FZHA 4TU5X 3FQVA 3F0XX 2LF1A 5CCCA 3F0VX 1RX7A 3GYFA 4FHBA 4PSSA 4PSTA 2JYBA 1KMSA 3CD2A 2BLBA 1U70A 1DLRA 3F8ZA 3JWCA 2BLAA 3IROA 1RX9A 3S3VA 2BL9A 1S3YA 5HUIA 4IXED 3ZPGA 1IA1A 2FZJA 1DLSA 1U72A 1RB2A 3FRAX 3NXTA 3JTWA 3CSEA 4X5FA 1DRBA 1VDRA 4QLFA 4XT8A 3F91A 3QG2A 1DR2A 2ITHA 5FDAA 3ROAA 1E26A 3TQ9A 1DIUA 4M7UA 4PTJA 4KM2A 4ELBA 3SAIA 4PDJA 3IA5A 4NX7A 2BLCA 5HF2X 5JG0X 4KM0A 1S3VA 3QYLA 5JA3A 1RX3A 4Q0EA 3NZBX 1U71A 5HVEA 2L28A 1RE7A 4QI9A 3QLZA 4IXFX 2ANQA 3KGYA 1RA8A 3NXRA 1LY3A 4HA9A 1DR5A 1DG5A 4HOEA 1DREA 3FQFA 4XT6A 4P66A
chains in the Genus database with same CATH superfamily
3NXOA 1DDRA 4ELEA 7DFRA 2XW7A 3SRRX 3SR5X 1DR6A 4XT5A 3FQ0A 1S3WA 2B3ZA 1S3UA 3FQOA 3HBBA 1JOMA 1RX2A 1RX5A 3K2HA 1DYHA 4RGCA 3SRSX 3EELA 3FRBX 1DHFA 3FY8X 1IA4A 3CLBA 3VCOA 2KGKA 4FGGA 1TDRA 1AOEA 2C2SA 4G95A 2GD9A 3D84X 3INVA 3RO9A 4Q0DA 3F8YA 4KJKA 4X5IA 3DG8A 4KAKA 1J3JA 4I1NA 3FY9X 3JVXA 1DG7A 2DHFA 3QLYA 2C2TA 4DPDA 2W9HA 3IRMA 1M78A 1HFPA 3JWMA 3QL3A 1RB3A 1PD8A 4H98A 2QK8A 4G8ZX 3NRRA 4QHVA 1IA3A 1J3KA 3NZDA 4KY8A 1PDBA 1DHIA 2CIGA 1YHOA 1RA2A 3UM5A 8DFRA 1RX1A 3KY8A 2W3WA 4IXGX 4DP3A 1M79A 1DRAA 3DFRA 1DYIA 1DR3A 1AI9A 2ANOA 3K74A 1VJ3A 3DL6A 5HI6A 3JW5A 5HT4A 3SRQX 3DRCA 3NU0A 1QZFA 2G6VA 4X5GA 3QGTA 3EX8A 1MVSA 4KLXA 2OIPA 1BOZA 3TD8A 3R33A 1RD7A 4PSYA 4H95A 2W9GA 1DHJA 3GI2A 1DAJA 1RA9A 4OSGA 3RG9A 1SEJA 2W9SA 4XT4A 3DAUA 3SA2A 3M08A 3CL9A 1LUDA 4KJJA 3S7AA 1RF7A 1DF7A 3QL0A 4ELFA 3SA1A 3S9UA 4KD7A 4M2XA 3DGAA 3IX9A 3FQCA 5HT5A 1DR7A 3OAFA 3N0HA 3QLWA 4HOFA 3FQZA 3FL8A 3EEMA 2W9TA 1RX4A 2HQPA 1OHKA 1HFRA 2ZZAA 3NXYA 1RX8A 3SRWX 4ELGA 4KY4A 3FS6A 1HFQA 2CD2A 2H2QA 4P68A 4X5HA 1DRHA 1RC4A 4KBNA 4KEBA 3FL9A 5EAJA 3IRNA 4X5JA 4LEKX 4P3QA 2W3BA 2FZIA 3JSUA 4OR7A 2W3MA 4KYAA 3GHWA 4M6LA 1M7AA 4XECX 6DFRA 3FRFX 3UM6A 3KFYA 3K47A 2D0KA 5HPBA 3SH2A 3M09A 5U26A 4G3MA 4DPHA 3KJSA 4NX6A 1AO8A 1DRFA 4H97A 4Q67A 4XT7A 3JW3A 1KLKA 3NXVA 4EJ1A 1CD2A 1DR1A 2O7PA 3QFXA 5HQZA 4LAHX 3SQYX 5CC9A 2DRCA 5DXVA 1DDSA 1LY4A 3NZCX 3GHVA 4M6JA 4EIGA 5E8QA 2W3VA 3NXXA 1DG8A 1JUVA 4QLGA 1PD9A 3F0BX 1KMVA 2AZNA 3D80A 3FYVX 3FREX 5HSUA 2INQA 3LG4A 4EIZA 3JWFA 4XRBA 2HM9A 1DYJA 2P4GA 4P3RA 1RA1A 3F0SX 3TQAA 5HSRA 4HOGA 3NZ9X 3KJRA 4DFRA 4FGHA 2HXVA 4QJZD 1MVTA 1JOLA 4KL9A 4EILA 3DATA 4Q6AA 4LAEX 3IA4A 3QLRA 3EEJA 5HVBA 4LAGX 3UM8A 3FYWX 4GH8A 4ECKA 3EIGA 1D1GA 4H96A 4CD2A 3FRDX 4DDRA 4HA7A 5HQYA 1ZDRA 3Q1HA 3HJ3A 3NZ6X 1CZ3A 1DR4A 4I13A 3QYOA 4QLEA 1DYRA 3NTZA 4M6KA 5ECCA 1RG7A 3F0UX 1RH3A 4KNEA 4KJLA 3TQ8A 3K45A 3EEKA 3SGYA 4ELHA 4KFJA 1J3IA 3SRUX 4XE6X 3NZAX 5DFRA 4QJCA 1DISA 3I8AX 3ZPCA 3GHCA 3OCHA 3L3RA 5ECXA 3E0BA 4PTHA 3DL5A 5HF0X 1RX6A 3QLSA 1RA3A 3QLXA 3F0QX 2OBCA 4M7VA 3TQBA 3I3RA 1IA2A 5U27A 3JWKA 1OHJA 2W3AA 1BZFA 2D5NA 2FZHA 4TU5X 3FQVA 3F0XX 2LF1A 5CCCA 3F0VX 1RX7A 3GYFA 4FHBA 4PSSA 4PSTA 2JYBA 1KMSA 3CD2A 2BLBA 1U70A 1DLRA 3F8ZA 3JWCA 2BLAA 3IROA 1RX9A 3S3VA 2BL9A 1S3YA 5HUIA 4IXED 3ZPGA 1IA1A 2FZJA 1DLSA 1U72A 1RB2A 3FRAX 3NXTA 3JTWA 3CSEA 4X5FA 1DRBA 1VDRA 4QLFA 4XT8A 3F91A 3QG2A 1DR2A 2ITHA 5FDAA 3ROAA 1E26A 3TQ9A 1DIUA 4M7UA 4PTJA 4KM2A 4ELBA 3SAIA 4PDJA 3IA5A 4NX7A 2BLCA 5HF2X 5JG0X 4KM0A 1S3VA 3QYLA 5JA3A 1RX3A 4Q0EA 3NZBX 1U71A 5HVEA 2L28A 1RE7A 4QI9A 3QLZA 4IXFX 2ANQA 3KGYA 1RA8A 3NXRA 1LY3A 4HA9A 1DR5A 1DG5A 4HOEA 1DREA 3FQFA 4XT6A 4P66A
chains in the Genus database with same CATH topology
3NXOA 1DDRA 4ELEA 7DFRA 2XW7A 3SRRX 3SR5X 1DR6A 4XT5A 3FQ0A 1S3WA 2B3ZA 1S3UA 3FQOA 3HBBA 1JOMA 1RX2A 1RX5A 3K2HA 1DYHA 4RGCA 3SRSX 3EELA 3FRBX 1DHFA 3FY8X 1IA4A 3CLBA 3VCOA 2KGKA 4FGGA 1TDRA 1AOEA 2C2SA 4G95A 2GD9A 3D84X 3INVA 3RO9A 4Q0DA 3F8YA 4KJKA 4X5IA 3DG8A 4KAKA 1J3JA 4I1NA 3FY9X 3JVXA 1DG7A 2DHFA 3QLYA 2C2TA 4DPDA 2W9HA 3IRMA 1M78A 1HFPA 3JWMA 3QL3A 1RB3A 1PD8A 4H98A 2QK8A 4G8ZX 3NRRA 4QHVA 1IA3A 1J3KA 3NZDA 4KY8A 1PDBA 1DHIA 2CIGA 1YHOA 1RA2A 3UM5A 8DFRA 1RX1A 3KY8A 2W3WA 4IXGX 4DP3A 1M79A 1DRAA 3DFRA 1DYIA 1DR3A 1AI9A 2ANOA 3K74A 1VJ3A 3DL6A 5HI6A 3JW5A 5HT4A 3SRQX 3DRCA 3NU0A 1QZFA 2G6VA 4X5GA 3QGTA 3EX8A 1MVSA 4KLXA 2OIPA 1BOZA 3TD8A 3R33A 1RD7A 4PSYA 4H95A 2W9GA 1DHJA 3GI2A 1DAJA 1RA9A 4OSGA 3RG9A 1SEJA 2W9SA 4XT4A 3DAUA 3SA2A 3M08A 3CL9A 1LUDA 4KJJA 3S7AA 1RF7A 1DF7A 3QL0A 4ELFA 3SA1A 3S9UA 4KD7A 4M2XA 3DGAA 3IX9A 3FQCA 5HT5A 1DR7A 3OAFA 3N0HA 3QLWA 4HOFA 3FQZA 3FL8A 3EEMA 2W9TA 1RX4A 2HQPA 1OHKA 1HFRA 2ZZAA 3NXYA 1RX8A 3SRWX 4ELGA 4KY4A 3FS6A 1HFQA 2CD2A 2H2QA 4P68A 4X5HA 1DRHA 1RC4A 4KBNA 4KEBA 3FL9A 5EAJA 3IRNA 4X5JA 4LEKX 4P3QA 2W3BA 2FZIA 3JSUA 4OR7A 2W3MA 4KYAA 3GHWA 4M6LA 1M7AA 4XECX 6DFRA 3FRFX 3UM6A 3KFYA 3K47A 2D0KA 5HPBA 3SH2A 3M09A 5U26A 4G3MA 4DPHA 3KJSA 4NX6A 1AO8A 1DRFA 4H97A 4Q67A 4XT7A 3JW3A 1KLKA 3NXVA 4EJ1A 1CD2A 1DR1A 2O7PA 3QFXA 5HQZA 4LAHX 3SQYX 5CC9A 2DRCA 5DXVA 1DDSA 1LY4A 3NZCX 3GHVA 4M6JA 4EIGA 5E8QA 2W3VA 3NXXA 1DG8A 1JUVA 4QLGA 1PD9A 3F0BX 1KMVA 2AZNA 3D80A 3FYVX 3FREX 5HSUA 2INQA 3LG4A 4EIZA 3JWFA 4XRBA 2HM9A 1DYJA 2P4GA 4P3RA 1RA1A 3F0SX 3TQAA 5HSRA 4HOGA 3NZ9X 3KJRA 4DFRA 4FGHA 2HXVA 4QJZD 1MVTA 1JOLA 4KL9A 4EILA 3DATA 4Q6AA 4LAEX 3IA4A 3QLRA 3EEJA 5HVBA 4LAGX 3UM8A 3FYWX 4GH8A 4ECKA 3EIGA 1D1GA 4H96A 4CD2A 3FRDX 4DDRA 4HA7A 5HQYA 1ZDRA 3Q1HA 3HJ3A 3NZ6X 1CZ3A 1DR4A 4I13A 3QYOA 4QLEA 1DYRA 3NTZA 4M6KA 5ECCA 1RG7A 3F0UX 1RH3A 4KNEA 4KJLA 3TQ8A 3K45A 3EEKA 3SGYA 4ELHA 4KFJA 1J3IA 3SRUX 4XE6X 3NZAX 5DFRA 4QJCA 1DISA 3I8AX 3ZPCA 3GHCA 3OCHA 3L3RA 5ECXA 3E0BA 4PTHA 3DL5A 5HF0X 1RX6A 3QLSA 1RA3A 3QLXA 3F0QX 2OBCA 4M7VA 3TQBA 3I3RA 1IA2A 5U27A 3JWKA 1OHJA 2W3AA 1BZFA 2D5NA 2FZHA 4TU5X 3FQVA 3F0XX 2LF1A 5CCCA 3F0VX 1RX7A 3GYFA 4FHBA 4PSSA 4PSTA 2JYBA 1KMSA 3CD2A 2BLBA 1U70A 1DLRA 3F8ZA 3JWCA 2BLAA 3IROA 1RX9A 3S3VA 2BL9A 1S3YA 5HUIA 4IXED 3ZPGA 1IA1A 2FZJA 1DLSA 1U72A 1RB2A 3FRAX 3NXTA 3JTWA 3CSEA 4X5FA 1DRBA 1VDRA 4QLFA 4XT8A 3F91A 3QG2A 1DR2A 2ITHA 5FDAA 3ROAA 1E26A 3TQ9A 1DIUA 4M7UA 4PTJA 4KM2A 4ELBA 3SAIA 4PDJA 3IA5A 4NX7A 2BLCA 5HF2X 5JG0X 4KM0A 1S3VA 3QYLA 5JA3A 1RX3A 4Q0EA 3NZBX 1U71A 5HVEA 2L28A 1RE7A 4QI9A 3QLZA 4IXFX 2ANQA 3KGYA 1RA8A 3NXRA 1LY3A 4HA9A 1DR5A 1DG5A 4HOEA 1DREA 3FQFA 4XT6A 4P66A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NXO A;  1DDR A;  4ELE A;  7DFR A;  2XW7 A;  3SRR X;  3SR5 X;  1DR6 A;  4XT5 A;  3FQ0 A;  1S3W A;  2B3Z A;  1S3U A;  3FQO A;  3HBB A;  1JOM A;  1RX2 A;  1RX5 A;  3K2H A;  1DYH A;  4RGC A;  3SRS X;  3EEL A;  3FRB X;  1DHF A;  3FY8 X;  1IA4 A;  3CLB A;  3VCO A;  2KGK A;  4FGG A;  1TDR A;  1AOE A;  2C2S A;  4G95 A;  2GD9 A;  3D84 X;  3INV A;  3RO9 A;  4Q0D A;  3F8Y A;  4KJK A;  4X5I A;  3DG8 A;  4KAK A;  1J3J A;  4I1N A;  3FY9 X;  3JVX A;  1DG7 A;  2DHF A;  3QLY A;  2C2T A;  4DPD A;  2W9H A;  3IRM A;  1M78 A;  1HFP A;  3JWM A;  3QL3 A;  1RB3 A;  1PD8 A;  4H98 A;  2QK8 A;  4G8Z X;  3NRR A;  4QHV A;  1IA3 A;  1J3K A;  3NZD A;  4KY8 A;  1PDB A;  1DHI A;  2CIG A;  1YHO A;  1RA2 A;  3UM5 A;  8DFR A;  1RX1 A;  3KY8 A;  2W3W A;  4IXG X;  4DP3 A;  1M79 A;  1DRA A;  3DFR A;  1DYI A;  1DR3 A;  1AI9 A;  2ANO A;  3K74 A;  1VJ3 A;  3DL6 A;  5HI6 A;  3JW5 A;  5HT4 A;  3SRQ X;  3DRC A;  3NU0 A;  1QZF A;  2G6V A;  4X5G A;  3QGT A;  3EX8 A;  1MVS A;  4KLX A;  2OIP A;  1BOZ A;  3TD8 A;  3R33 A;  1RD7 A;  4PSY A;  4H95 A;  2W9G A;  1DHJ A;  3GI2 A;  1DAJ A;  1RA9 A;  4OSG A;  3RG9 A;  1SEJ A;  2W9S A;  4XT4 A;  3DAU A;  3SA2 A;  3M08 A;  3CL9 A;  1LUD A;  4KJJ A;  3S7A A;  1RF7 A;  1DF7 A;  3QL0 A;  4ELF A;  3SA1 A;  3S9U A;  4KD7 A;  4M2X A;  3DGA A;  3IX9 A;  3FQC A;  5HT5 A;  1DR7 A;  3OAF A;  3N0H A;  3QLW A;  4HOF A;  3FQZ A;  3FL8 A;  3EEM A;  2W9T A;  1RX4 A;  2HQP A;  1OHK A;  1HFR A;  2ZZA A;  3NXY A;  1RX8 A;  3SRW X;  4ELG A;  4KY4 A;  3FS6 A;  1HFQ A;  2CD2 A;  2H2Q A;  4P68 A;  4X5H A;  1DRH A;  1RC4 A;  4KBN A;  4KEB A;  3FL9 A;  5EAJ A;  3IRN A;  4X5J A;  4LEK X;  4P3Q A;  2W3B A;  2FZI A;  3JSU A;  4OR7 A;  2W3M A;  4KYA A;  3GHW A;  4M6L A;  1M7A A;  4XEC X;  6DFR A;  3FRF X;  3UM6 A;  3KFY A;  3K47 A;  2D0K A;  5HPB A;  3SH2 A;  3M09 A;  5U26 A;  4G3M A;  4DPH A;  3KJS A;  4NX6 A;  1AO8 A;  1DRF A;  4H97 A;  4Q67 A;  4XT7 A;  3JW3 A;  1KLK A;  3NXV A;  4EJ1 A;  1CD2 A;  1DR1 A;  2O7P A;  3QFX A;  5HQZ A;  4LAH X;  3SQY X;  5CC9 A;  2DRC A;  5DXV A;  1DDS A;  1LY4 A;  3NZC X;  3GHV A;  4M6J A;  4EIG A;  5E8Q A;  2W3V A;  3NXX A;  1DG8 A;  1JUV A;  4QLG A;  1PD9 A;  3F0B X;  1KMV A;  2AZN A;  3D80 A;  3FYV X;  3FRE X;  5HSU A;  2INQ A;  3LG4 A;  4EIZ A;  3JWF A;  4XRB A;  2HM9 A;  1DYJ A;  2P4G A;  4P3R A;  1RA1 A;  3F0S X;  3TQA A;  5HSR A;  4HOG A;  3NZ9 X;  3KJR A;  4DFR A;  4FGH A;  2HXV A;  4QJZ D;  1MVT A;  1JOL A;  4KL9 A;  4EIL A;  3DAT A;  4Q6A A;  4LAE X;  3IA4 A;  3QLR A;  3EEJ A;  5HVB A;  4LAG X;  3UM8 A;  3FYW X;  4GH8 A;  4ECK A;  3EIG A;  1D1G A;  4H96 A;  4CD2 A;  3FRD X;  4DDR A;  4HA7 A;  5HQY A;  1ZDR A;  3Q1H A;  3HJ3 A;  3NZ6 X;  1CZ3 A;  1DR4 A;  4I13 A;  3QYO A;  4QLE A;  1DYR A;  3NTZ A;  4M6K A;  5ECC A;  1RG7 A;  3F0U X;  1RH3 A;  4KNE A;  4KJL A;  3TQ8 A;  3K45 A;  3EEK A;  3SGY A;  4ELH A;  4KFJ A;  1J3I A;  3SRU X;  4XE6 X;  3NZA X;  5DFR A;  4QJC A;  1DIS A;  3I8A X;  3ZPC A;  3GHC A;  3OCH A;  3L3R A;  5ECX A;  3E0B A;  4PTH A;  3DL5 A;  5HF0 X;  1RX6 A;  3QLS A;  1RA3 A;  3QLX A;  3F0Q X;  2OBC A;  4M7V A;  3TQB A;  3I3R A;  1IA2 A;  5U27 A;  3JWK A;  1OHJ A;  2W3A A;  1BZF A;  2D5N A;  2FZH A;  4TU5 X;  3FQV A;  3F0X X;  2LF1 A;  5CCC A;  3F0V X;  1RX7 A;  3GYF A;  4FHB A;  4PSS A;  4PST A;  2JYB A;  1KMS A;  3CD2 A;  2BLB A;  1U70 A;  1DLR A;  3F8Z A;  3JWC A;  2BLA A;  3IRO A;  1RX9 A;  3S3V A;  2BL9 A;  1S3Y A;  5HUI A;  4IXE D;  3ZPG A;  1IA1 A;  2FZJ A;  1DLS A;  1U72 A;  1RB2 A;  3FRA X;  3NXT A;  3JTW A;  3CSE A;  4X5F A;  1DRB A;  1VDR A;  4QLF A;  4XT8 A;  3F91 A;  3QG2 A;  1DR2 A;  2ITH A;  5FDA A;  3ROA A;  1E26 A;  3TQ9 A;  1DIU A;  4M7U A;  4PTJ A;  4KM2 A;  4ELB A;  3SAI A;  4PDJ A;  3IA5 A;  4NX7 A;  2BLC A;  5HF2 X;  5JG0 X;  4KM0 A;  1S3V A;  3QYL A;  5JA3 A;  1RX3 A;  4Q0E A;  3NZB X;  1U71 A;  5HVE A;  2L28 A;  1RE7 A;  4QI9 A;  3QLZ A;  4IXF X;  2ANQ A;  3KGY A;  1RA8 A;  3NXR A;  1LY3 A;  4HA9 A;  1DR5 A;  1DG5 A;  4HOE A;  1DRE A;  3FQF A;  4XT6 A;  4P66 A; 
#chains in the Genus database with same CATH topology
 3NXO A;  1DDR A;  4ELE A;  7DFR A;  2XW7 A;  3SRR X;  3SR5 X;  1DR6 A;  4XT5 A;  3FQ0 A;  1S3W A;  2B3Z A;  1S3U A;  3FQO A;  3HBB A;  1JOM A;  1RX2 A;  1RX5 A;  3K2H A;  1DYH A;  4RGC A;  3SRS X;  3EEL A;  3FRB X;  1DHF A;  3FY8 X;  1IA4 A;  3CLB A;  3VCO A;  2KGK A;  4FGG A;  1TDR A;  1AOE A;  2C2S A;  4G95 A;  2GD9 A;  3D84 X;  3INV A;  3RO9 A;  4Q0D A;  3F8Y A;  4KJK A;  4X5I A;  3DG8 A;  4KAK A;  1J3J A;  4I1N A;  3FY9 X;  3JVX A;  1DG7 A;  2DHF A;  3QLY A;  2C2T A;  4DPD A;  2W9H A;  3IRM A;  1M78 A;  1HFP A;  3JWM A;  3QL3 A;  1RB3 A;  1PD8 A;  4H98 A;  2QK8 A;  4G8Z X;  3NRR A;  4QHV A;  1IA3 A;  1J3K A;  3NZD A;  4KY8 A;  1PDB A;  1DHI A;  2CIG A;  1YHO A;  1RA2 A;  3UM5 A;  8DFR A;  1RX1 A;  3KY8 A;  2W3W A;  4IXG X;  4DP3 A;  1M79 A;  1DRA A;  3DFR A;  1DYI A;  1DR3 A;  1AI9 A;  2ANO A;  3K74 A;  1VJ3 A;  3DL6 A;  5HI6 A;  3JW5 A;  5HT4 A;  3SRQ X;  3DRC A;  3NU0 A;  1QZF A;  2G6V A;  4X5G A;  3QGT A;  3EX8 A;  1MVS A;  4KLX A;  2OIP A;  1BOZ A;  3TD8 A;  3R33 A;  1RD7 A;  4PSY A;  4H95 A;  2W9G A;  1DHJ A;  3GI2 A;  1DAJ A;  1RA9 A;  4OSG A;  3RG9 A;  1SEJ A;  2W9S A;  4XT4 A;  3DAU A;  3SA2 A;  3M08 A;  3CL9 A;  1LUD A;  4KJJ A;  3S7A A;  1RF7 A;  1DF7 A;  3QL0 A;  4ELF A;  3SA1 A;  3S9U A;  4KD7 A;  4M2X A;  3DGA A;  3IX9 A;  3FQC A;  5HT5 A;  1DR7 A;  3OAF A;  3N0H A;  3QLW A;  4HOF A;  3FQZ A;  3FL8 A;  3EEM A;  2W9T A;  1RX4 A;  2HQP A;  1OHK A;  1HFR A;  2ZZA A;  3NXY A;  1RX8 A;  3SRW X;  4ELG A;  4KY4 A;  3FS6 A;  1HFQ A;  2CD2 A;  2H2Q A;  4P68 A;  4X5H A;  1DRH A;  1RC4 A;  4KBN A;  4KEB A;  3FL9 A;  5EAJ A;  3IRN A;  4X5J A;  4LEK X;  4P3Q A;  2W3B A;  2FZI A;  3JSU A;  4OR7 A;  2W3M A;  4KYA A;  3GHW A;  4M6L A;  1M7A A;  4XEC X;  6DFR A;  3FRF X;  3UM6 A;  3KFY A;  3K47 A;  2D0K A;  5HPB A;  3SH2 A;  3M09 A;  5U26 A;  4G3M A;  4DPH A;  3KJS A;  4NX6 A;  1AO8 A;  1DRF A;  4H97 A;  4Q67 A;  4XT7 A;  3JW3 A;  1KLK A;  3NXV A;  4EJ1 A;  1CD2 A;  1DR1 A;  2O7P A;  3QFX A;  5HQZ A;  4LAH X;  3SQY X;  5CC9 A;  2DRC A;  5DXV A;  1DDS A;  1LY4 A;  3NZC X;  3GHV A;  4M6J A;  4EIG A;  5E8Q A;  2W3V A;  3NXX A;  1DG8 A;  1JUV A;  4QLG A;  1PD9 A;  3F0B X;  1KMV A;  2AZN A;  3D80 A;  3FYV X;  3FRE X;  5HSU A;  2INQ A;  3LG4 A;  4EIZ A;  3JWF A;  4XRB A;  2HM9 A;  1DYJ A;  2P4G A;  4P3R A;  1RA1 A;  3F0S X;  3TQA A;  5HSR A;  4HOG A;  3NZ9 X;  3KJR A;  4DFR A;  4FGH A;  2HXV A;  4QJZ D;  1MVT A;  1JOL A;  4KL9 A;  4EIL A;  3DAT A;  4Q6A A;  4LAE X;  3IA4 A;  3QLR A;  3EEJ A;  5HVB A;  4LAG X;  3UM8 A;  3FYW X;  4GH8 A;  4ECK A;  3EIG A;  1D1G A;  4H96 A;  4CD2 A;  3FRD X;  4DDR A;  4HA7 A;  5HQY A;  1ZDR A;  3Q1H A;  3HJ3 A;  3NZ6 X;  1CZ3 A;  1DR4 A;  4I13 A;  3QYO A;  4QLE A;  1DYR A;  3NTZ A;  4M6K A;  5ECC A;  1RG7 A;  3F0U X;  1RH3 A;  4KNE A;  4KJL A;  3TQ8 A;  3K45 A;  3EEK A;  3SGY A;  4ELH A;  4KFJ A;  1J3I A;  3SRU X;  4XE6 X;  3NZA X;  5DFR A;  4QJC A;  1DIS A;  3I8A X;  3ZPC A;  3GHC A;  3OCH A;  3L3R A;  5ECX A;  3E0B A;  4PTH A;  3DL5 A;  5HF0 X;  1RX6 A;  3QLS A;  1RA3 A;  3QLX A;  3F0Q X;  2OBC A;  4M7V A;  3TQB A;  3I3R A;  1IA2 A;  5U27 A;  3JWK A;  1OHJ A;  2W3A A;  1BZF A;  2D5N A;  2FZH A;  4TU5 X;  3FQV A;  3F0X X;  2LF1 A;  5CCC A;  3F0V X;  1RX7 A;  3GYF A;  4FHB A;  4PSS A;  4PST A;  2JYB A;  1KMS A;  3CD2 A;  2BLB A;  1U70 A;  1DLR A;  3F8Z A;  3JWC A;  2BLA A;  3IRO A;  1RX9 A;  3S3V A;  2BL9 A;  1S3Y A;  5HUI A;  4IXE D;  3ZPG A;  1IA1 A;  2FZJ A;  1DLS A;  1U72 A;  1RB2 A;  3FRA X;  3NXT A;  3JTW A;  3CSE A;  4X5F A;  1DRB A;  1VDR A;  4QLF A;  4XT8 A;  3F91 A;  3QG2 A;  1DR2 A;  2ITH A;  5FDA A;  3ROA A;  1E26 A;  3TQ9 A;  1DIU A;  4M7U A;  4PTJ A;  4KM2 A;  4ELB A;  3SAI A;  4PDJ A;  3IA5 A;  4NX7 A;  2BLC A;  5HF2 X;  5JG0 X;  4KM0 A;  1S3V A;  3QYL A;  5JA3 A;  1RX3 A;  4Q0E A;  3NZB X;  1U71 A;  5HVE A;  2L28 A;  1RE7 A;  4QI9 A;  3QLZ A;  4IXF X;  2ANQ A;  3KGY A;  1RA8 A;  3NXR A;  1LY3 A;  4HA9 A;  1DR5 A;  1DG5 A;  4HOE A;  1DRE A;  3FQF A;  4XT6 A;  4P66 A; 
#chains in the Genus database with same CATH homology
 3NXO A;  1DDR A;  4ELE A;  7DFR A;  2XW7 A;  3SRR X;  3SR5 X;  1DR6 A;  4XT5 A;  3FQ0 A;  1S3W A;  2B3Z A;  1S3U A;  3FQO A;  3HBB A;  1JOM A;  1RX2 A;  1RX5 A;  3K2H A;  1DYH A;  4RGC A;  3SRS X;  3EEL A;  3FRB X;  1DHF A;  3FY8 X;  1IA4 A;  3CLB A;  3VCO A;  2KGK A;  4FGG A;  1TDR A;  1AOE A;  2C2S A;  4G95 A;  2GD9 A;  3D84 X;  3INV A;  3RO9 A;  4Q0D A;  3F8Y A;  4KJK A;  4X5I A;  3DG8 A;  4KAK A;  1J3J A;  4I1N A;  3FY9 X;  3JVX A;  1DG7 A;  2DHF A;  3QLY A;  2C2T A;  4DPD A;  2W9H A;  3IRM A;  1M78 A;  1HFP A;  3JWM A;  3QL3 A;  1RB3 A;  1PD8 A;  4H98 A;  2QK8 A;  4G8Z X;  3NRR A;  4QHV A;  1IA3 A;  1J3K A;  3NZD A;  4KY8 A;  1PDB A;  1DHI A;  2CIG A;  1YHO A;  1RA2 A;  3UM5 A;  8DFR A;  1RX1 A;  3KY8 A;  2W3W A;  4IXG X;  4DP3 A;  1M79 A;  1DRA A;  3DFR A;  1DYI A;  1DR3 A;  1AI9 A;  2ANO A;  3K74 A;  1VJ3 A;  3DL6 A;  5HI6 A;  3JW5 A;  5HT4 A;  3SRQ X;  3DRC A;  3NU0 A;  1QZF A;  2G6V A;  4X5G A;  3QGT A;  3EX8 A;  1MVS A;  4KLX A;  2OIP A;  1BOZ A;  3TD8 A;  3R33 A;  1RD7 A;  4PSY A;  4H95 A;  2W9G A;  1DHJ A;  3GI2 A;  1DAJ A;  1RA9 A;  4OSG A;  3RG9 A;  1SEJ A;  2W9S A;  4XT4 A;  3DAU A;  3SA2 A;  3M08 A;  3CL9 A;  1LUD A;  4KJJ A;  3S7A A;  1RF7 A;  1DF7 A;  3QL0 A;  4ELF A;  3SA1 A;  3S9U A;  4KD7 A;  4M2X A;  3DGA A;  3IX9 A;  3FQC A;  5HT5 A;  1DR7 A;  3OAF A;  3N0H A;  3QLW A;  4HOF A;  3FQZ A;  3FL8 A;  3EEM A;  2W9T A;  1RX4 A;  2HQP A;  1OHK A;  1HFR A;  2ZZA A;  3NXY A;  1RX8 A;  3SRW X;  4ELG A;  4KY4 A;  3FS6 A;  1HFQ A;  2CD2 A;  2H2Q A;  4P68 A;  4X5H A;  1DRH A;  1RC4 A;  4KBN A;  4KEB A;  3FL9 A;  5EAJ A;  3IRN A;  4X5J A;  4LEK X;  4P3Q A;  2W3B A;  2FZI A;  3JSU A;  4OR7 A;  2W3M A;  4KYA A;  3GHW A;  4M6L A;  1M7A A;  4XEC X;  6DFR A;  3FRF X;  3UM6 A;  3KFY A;  3K47 A;  2D0K A;  5HPB A;  3SH2 A;  3M09 A;  5U26 A;  4G3M A;  4DPH A;  3KJS A;  4NX6 A;  1AO8 A;  1DRF A;  4H97 A;  4Q67 A;  4XT7 A;  3JW3 A;  1KLK A;  3NXV A;  4EJ1 A;  1CD2 A;  1DR1 A;  2O7P A;  3QFX A;  5HQZ A;  4LAH X;  3SQY X;  5CC9 A;  2DRC A;  5DXV A;  1DDS A;  1LY4 A;  3NZC X;  3GHV A;  4M6J A;  4EIG A;  5E8Q A;  2W3V A;  3NXX A;  1DG8 A;  1JUV A;  4QLG A;  1PD9 A;  3F0B X;  1KMV A;  2AZN A;  3D80 A;  3FYV X;  3FRE X;  5HSU A;  2INQ A;  3LG4 A;  4EIZ A;  3JWF A;  4XRB A;  2HM9 A;  1DYJ A;  2P4G A;  4P3R A;  1RA1 A;  3F0S X;  3TQA A;  5HSR A;  4HOG A;  3NZ9 X;  3KJR A;  4DFR A;  4FGH A;  2HXV A;  4QJZ D;  1MVT A;  1JOL A;  4KL9 A;  4EIL A;  3DAT A;  4Q6A A;  4LAE X;  3IA4 A;  3QLR A;  3EEJ A;  5HVB A;  4LAG X;  3UM8 A;  3FYW X;  4GH8 A;  4ECK A;  3EIG A;  1D1G A;  4H96 A;  4CD2 A;  3FRD X;  4DDR A;  4HA7 A;  5HQY A;  1ZDR A;  3Q1H A;  3HJ3 A;  3NZ6 X;  1CZ3 A;  1DR4 A;  4I13 A;  3QYO A;  4QLE A;  1DYR A;  3NTZ A;  4M6K A;  5ECC A;  1RG7 A;  3F0U X;  1RH3 A;  4KNE A;  4KJL A;  3TQ8 A;  3K45 A;  3EEK A;  3SGY A;  4ELH A;  4KFJ A;  1J3I A;  3SRU X;  4XE6 X;  3NZA X;  5DFR A;  4QJC A;  1DIS A;  3I8A X;  3ZPC A;  3GHC A;  3OCH A;  3L3R A;  5ECX A;  3E0B A;  4PTH A;  3DL5 A;  5HF0 X;  1RX6 A;  3QLS A;  1RA3 A;  3QLX A;  3F0Q X;  2OBC A;  4M7V A;  3TQB A;  3I3R A;  1IA2 A;  5U27 A;  3JWK A;  1OHJ A;  2W3A A;  1BZF A;  2D5N A;  2FZH A;  4TU5 X;  3FQV A;  3F0X X;  2LF1 A;  5CCC A;  3F0V X;  1RX7 A;  3GYF A;  4FHB A;  4PSS A;  4PST A;  2JYB A;  1KMS A;  3CD2 A;  2BLB A;  1U70 A;  1DLR A;  3F8Z A;  3JWC A;  2BLA A;  3IRO A;  1RX9 A;  3S3V A;  2BL9 A;  1S3Y A;  5HUI A;  4IXE D;  3ZPG A;  1IA1 A;  2FZJ A;  1DLS A;  1U72 A;  1RB2 A;  3FRA X;  3NXT A;  3JTW A;  3CSE A;  4X5F A;  1DRB A;  1VDR A;  4QLF A;  4XT8 A;  3F91 A;  3QG2 A;  1DR2 A;  2ITH A;  5FDA A;  3ROA A;  1E26 A;  3TQ9 A;  1DIU A;  4M7U A;  4PTJ A;  4KM2 A;  4ELB A;  3SAI A;  4PDJ A;  3IA5 A;  4NX7 A;  2BLC A;  5HF2 X;  5JG0 X;  4KM0 A;  1S3V A;  3QYL A;  5JA3 A;  1RX3 A;  4Q0E A;  3NZB X;  1U71 A;  5HVE A;  2L28 A;  1RE7 A;  4QI9 A;  3QLZ A;  4IXF X;  2ANQ A;  3KGY A;  1RA8 A;  3NXR A;  1LY3 A;  4HA9 A;  1DR5 A;  1DG5 A;  4HOE A;  1DRE A;  3FQF A;  4XT6 A;  4P66 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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