3FQVA

Staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 39
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fqvA00
1DRBA 2BL9A 3QLYA 3SH2A 3KJRA 3S9UA 5HF2X 3SA2A 4X5FA 2INQA 1DR5A 1KLKA 1IA2A 4XT4A 3S7AA 4PTHA 3Q1HA 3GI2A 3VCOA 3F8YA 3SR5X 4HOEA 3QLZA 3FYVX 4H96A 1CZ3A 2ZZAA 3UM5A 4P66A 3EX8A 5E8QA 4ELEA 3JWKA 1RD7A 3SRSX 1DAJA 5FDAA 5ECXA 1DRHA 2W3AA 3IX9A 3QLWA 4X5HA 3SAIA 1RC4A 4KM0A 3M09A 3NZAX 1DHJA 3JW3A 5U27A 3UM8A 2CIGA 2P4GA 1AOEA 4DP3A 3F0QX 5HPBA 3QYLA 1RX3A 2BLCA 2DRCA 1OHJA 4PSSA 3NRRA 4EIGA 3FL9A 3NU0A 3FRFX 2W9SA 4EILA 3NZ9X 1HFQA 2O7PA 3JWFA 1RA9A 3GHCA 1DDSA 2W3WA 5U26A 2ANQA 3QL3A 1RF7A 1J3KA 3DATA 5HVBA 3K45A 2FZHA 3TQAA 3TQ9A 2B3ZA 1YHOA 1PD9A 4EIZA 3N0HA 5JG0X 1RA8A 4KJJA 4XT6A 3K47A 1IA3A 3JWCA 3SGYA 3IRNA 3SRWX 4Q0DA 1DR7A 4DFRA 4LAGX 4QJCA 2DHFA 3RG9A 1DR3A 2HQPA 3HBBA 4X5JA 5HSRA 2ITHA 3EEJA 4G3MA 4M7UA 5EAJA 5HI6A 3DG8A 4I1NA 3DGAA 3FY8X 1RX1A 3DRCA 4ECKA 4GH8A 1DG8A 3KGYA 3RO9A 3FRAX 4XT8A 4XRBA 2LF1A 3FY9X 1IA4A 4KBNA 3EELA 1MVTA 2HXVA 3HJ3A 4ELBA 1RX9A 4PDJA 1KMSA 1BZFA 3JWMA 2FZIA 3IA5A 4IXED 1D1GA 3FYWX 4XECX 1LY4A 4M6KA 4X5IA 3K74A 5HUIA 4CD2A 4Q0EA 3F0BX 3GHVA 3QLXA 3K2HA 1DIUA 3E0BA 2W9HA 1RX6A 3TQ8A 1HFRA 1RX4A 4G8ZX 3SQYX 4PTJA 4FHBA 1AO8A 4IXFX 3DL6A 3CL9A 3F0UX 4H98A 1RE7A 1U71A 3FS6A 5HSUA 1RA2A 1S3VA 4M2XA 4ELFA 1RB2A 3S3VA 3I3RA 4Q6AA 4P3QA 2OIPA 3JSUA 4XT7A 2QK8A 1DR4A 3FQVA 8DFRA 4KJLA 3TQBA 2BLBA 3OCHA 1HFPA 1E26A 2W3MA 1BOZA 7DFRA 3DL5A 4FGGA 3QFXA 3NXVA 3ZPGA 4KAKA 4M6JA 1LUDA 3F8ZA 2JYBA 4QHVA 4KEBA 1DF7A 2GD9A 1RX7A 6DFRA 1RA1A 3CD2A 2G6VA 2L28A 1DR1A 2BLAA 3DAUA 1DHIA 1VDRA 4HA9A 4OR7A 1VJ3A 3FREX 5HT4A 5HQZA 1M7AA 5HT5A 3FQZA 1RG7A 4M7VA 4EJ1A 3FQCA 1JUVA 3IRMA 2W9TA 3OAFA 1PDBA 1RX8A 2W3BA 1JOLA 1DRAA 4QJZD 3ZPCA 4DPHA 5DXVA 4DPDA 3L3RA 1S3YA 1DG5A 4KNEA 2D0KA 3SRRX 1DR6A 5ECCA 1DR2A 3JW5A 1KMVA 4HOFA 2FZJA 3NXXA 2C2SA 1MVSA 4H95A 5CC9A 4Q67A 2W9GA 3D80A 4ELHA 4ELGA 4DDRA 3FQOA 3SRQX 1DYHA 2D5NA 3SRUX 3NZCX 1U70A 1DYRA 5HVEA 3GYFA 1SEJA 1J3JA 4KD7A 3ROAA 1J3IA 1S3UA 4RGCA 4NX6A 3QL0A 4KLXA 2CD2A 3EEMA 3LG4A 2KGKA 4KJKA 4QLFA 5JA3A 1DLRA 1DISA 4X5GA 4QLEA 4LAEX 3NXOA 3NXTA 1DLSA 1S3WA 4P3RA 4H97A 4QLGA 3GHWA 3CSEA 3QGTA 3TD8A 4KFJA 3F0VX 1OHKA 1ZDRA 3FL8A 3QLRA 3KFYA 2ANOA 2H2QA 1IA1A 1U72A 3QLSA 4XT5A 1DHFA 4QI9A 1LY3A 3QYOA 1DRFA 3FRDX 3IROA 2C2TA 4KL9A 5DFRA 4NX7A 4KYAA 1M79A 1DG7A 4PSTA 3NZ6X 4XE6X 1M78A 1RX2A 3F0SX 4TU5X 4KY8A 5CCCA 4P68A 3NZDA 1RB3A 4M6LA 3R33A 4HOGA 3FQ0A 3I8AX 3KJSA 4I13A 1JOMA 1RA3A 1DREA 3FRBX 2XW7A 3KY8A 3NXRA 1DYIA 3NZBX 3SA1A 1DDRA 3DFRA 1RH3A 3JVXA 1QZFA 4LAHX 1PD8A 2W3VA 3F91A 5HF0X 3FQFA 3M08A 1CD2A 3NXYA 1DYJA 3JTWA 3QG2A 2OBCA 4KM2A 4KY4A 1TDRA 3EIGA 5HQYA 4G95A 3D84X 4FGHA 4IXGX 4PSYA 3CLBA 3NTZA 3INVA 1RX5A 4LEKX 2HM9A 3UM6A 3F0XX 4HA7A 3IA4A 1AI9A 3EEKA 2AZNA 4OSGA
chains in the Genus database with same CATH superfamily
1DRBA 2BL9A 3QLYA 3SH2A 3KJRA 3S9UA 5HF2X 3SA2A 4X5FA 2INQA 1DR5A 1KLKA 1IA2A 4XT4A 3S7AA 4PTHA 3Q1HA 3GI2A 3VCOA 3F8YA 3SR5X 4HOEA 3QLZA 3FYVX 4H96A 1CZ3A 2ZZAA 3UM5A 4P66A 3EX8A 5E8QA 4ELEA 3JWKA 1RD7A 3SRSX 1DAJA 5FDAA 5ECXA 1DRHA 2W3AA 3IX9A 3QLWA 4X5HA 3SAIA 1RC4A 4KM0A 3M09A 3NZAX 1DHJA 3JW3A 5U27A 3UM8A 2CIGA 2P4GA 1AOEA 4DP3A 3F0QX 5HPBA 3QYLA 1RX3A 2BLCA 2DRCA 1OHJA 4PSSA 3NRRA 4EIGA 3FL9A 3NU0A 3FRFX 2W9SA 4EILA 3NZ9X 1HFQA 2O7PA 3JWFA 1RA9A 3GHCA 1DDSA 2W3WA 5U26A 2ANQA 3QL3A 1RF7A 1J3KA 3DATA 5HVBA 3K45A 2FZHA 3TQAA 3TQ9A 2B3ZA 1YHOA 1PD9A 4EIZA 3N0HA 5JG0X 1RA8A 4KJJA 4XT6A 3K47A 1IA3A 3JWCA 3SGYA 3IRNA 3SRWX 4Q0DA 1DR7A 4DFRA 4LAGX 4QJCA 2DHFA 3RG9A 1DR3A 2HQPA 3HBBA 4X5JA 5HSRA 2ITHA 3EEJA 4G3MA 4M7UA 5EAJA 5HI6A 3DG8A 4I1NA 3DGAA 3FY8X 1RX1A 3DRCA 4ECKA 4GH8A 1DG8A 3KGYA 3RO9A 3FRAX 4XT8A 4XRBA 2LF1A 3FY9X 1IA4A 4KBNA 3EELA 1MVTA 2HXVA 3HJ3A 4ELBA 1RX9A 4PDJA 1KMSA 1BZFA 3JWMA 2FZIA 3IA5A 4IXED 1D1GA 3FYWX 4XECX 1LY4A 4M6KA 4X5IA 3K74A 5HUIA 4CD2A 4Q0EA 3F0BX 3GHVA 3QLXA 3K2HA 1DIUA 3E0BA 2W9HA 1RX6A 3TQ8A 1HFRA 1RX4A 4G8ZX 3SQYX 4PTJA 4FHBA 1AO8A 4IXFX 3DL6A 3CL9A 3F0UX 4H98A 1RE7A 1U71A 3FS6A 5HSUA 1RA2A 1S3VA 4M2XA 4ELFA 1RB2A 3S3VA 3I3RA 4Q6AA 4P3QA 2OIPA 3JSUA 4XT7A 2QK8A 1DR4A 3FQVA 8DFRA 4KJLA 3TQBA 2BLBA 3OCHA 1HFPA 1E26A 2W3MA 1BOZA 7DFRA 3DL5A 4FGGA 3QFXA 3NXVA 3ZPGA 4KAKA 4M6JA 1LUDA 3F8ZA 2JYBA 4QHVA 4KEBA 1DF7A 2GD9A 1RX7A 6DFRA 1RA1A 3CD2A 2G6VA 2L28A 1DR1A 2BLAA 3DAUA 1DHIA 1VDRA 4HA9A 4OR7A 1VJ3A 3FREX 5HT4A 5HQZA 1M7AA 5HT5A 3FQZA 1RG7A 4M7VA 4EJ1A 3FQCA 1JUVA 3IRMA 2W9TA 3OAFA 1PDBA 1RX8A 2W3BA 1JOLA 1DRAA 4QJZD 3ZPCA 4DPHA 5DXVA 4DPDA 3L3RA 1S3YA 1DG5A 4KNEA 2D0KA 3SRRX 1DR6A 5ECCA 1DR2A 3JW5A 1KMVA 4HOFA 2FZJA 3NXXA 2C2SA 1MVSA 4H95A 5CC9A 4Q67A 2W9GA 3D80A 4ELHA 4ELGA 4DDRA 3FQOA 3SRQX 1DYHA 2D5NA 3SRUX 3NZCX 1U70A 1DYRA 5HVEA 3GYFA 1SEJA 1J3JA 4KD7A 3ROAA 1J3IA 1S3UA 4RGCA 4NX6A 3QL0A 4KLXA 2CD2A 3EEMA 3LG4A 2KGKA 4KJKA 4QLFA 5JA3A 1DLRA 1DISA 4X5GA 4QLEA 4LAEX 3NXOA 3NXTA 1DLSA 1S3WA 4P3RA 4H97A 4QLGA 3GHWA 3CSEA 3QGTA 3TD8A 4KFJA 3F0VX 1OHKA 1ZDRA 3FL8A 3QLRA 3KFYA 2ANOA 2H2QA 1IA1A 1U72A 3QLSA 4XT5A 1DHFA 4QI9A 1LY3A 3QYOA 1DRFA 3FRDX 3IROA 2C2TA 4KL9A 5DFRA 4NX7A 4KYAA 1M79A 1DG7A 4PSTA 3NZ6X 4XE6X 1M78A 1RX2A 3F0SX 4TU5X 4KY8A 5CCCA 4P68A 3NZDA 1RB3A 4M6LA 3R33A 4HOGA 3FQ0A 3I8AX 3KJSA 4I13A 1JOMA 1RA3A 1DREA 3FRBX 2XW7A 3KY8A 3NXRA 1DYIA 3NZBX 3SA1A 1DDRA 3DFRA 1RH3A 3JVXA 1QZFA 4LAHX 1PD8A 2W3VA 3F91A 5HF0X 3FQFA 3M08A 1CD2A 3NXYA 1DYJA 3JTWA 3QG2A 2OBCA 4KM2A 4KY4A 1TDRA 3EIGA 5HQYA 4G95A 3D84X 4FGHA 4IXGX 4PSYA 3CLBA 3NTZA 3INVA 1RX5A 4LEKX 2HM9A 3UM6A 3F0XX 4HA7A 3IA4A 1AI9A 3EEKA 2AZNA 4OSGA
chains in the Genus database with same CATH topology
1DRBA 2BL9A 3QLYA 3SH2A 3KJRA 3S9UA 5HF2X 3SA2A 4X5FA 2INQA 1DR5A 1KLKA 1IA2A 4XT4A 3S7AA 4PTHA 3Q1HA 3GI2A 3VCOA 3F8YA 3SR5X 4HOEA 3QLZA 3FYVX 4H96A 1CZ3A 2ZZAA 3UM5A 4P66A 3EX8A 5E8QA 4ELEA 3JWKA 1RD7A 3SRSX 1DAJA 5FDAA 5ECXA 1DRHA 2W3AA 3IX9A 3QLWA 4X5HA 3SAIA 1RC4A 4KM0A 3M09A 3NZAX 1DHJA 3JW3A 5U27A 3UM8A 2CIGA 2P4GA 1AOEA 4DP3A 3F0QX 5HPBA 3QYLA 1RX3A 2BLCA 2DRCA 1OHJA 4PSSA 3NRRA 4EIGA 3FL9A 3NU0A 3FRFX 2W9SA 4EILA 3NZ9X 1HFQA 2O7PA 3JWFA 1RA9A 3GHCA 1DDSA 2W3WA 5U26A 2ANQA 3QL3A 1RF7A 1J3KA 3DATA 5HVBA 3K45A 2FZHA 3TQAA 3TQ9A 2B3ZA 1YHOA 1PD9A 4EIZA 3N0HA 5JG0X 1RA8A 4KJJA 4XT6A 3K47A 1IA3A 3JWCA 3SGYA 3IRNA 3SRWX 4Q0DA 1DR7A 4DFRA 4LAGX 4QJCA 2DHFA 3RG9A 1DR3A 2HQPA 3HBBA 4X5JA 5HSRA 2ITHA 3EEJA 4G3MA 4M7UA 5EAJA 5HI6A 3DG8A 4I1NA 3DGAA 3FY8X 1RX1A 3DRCA 4ECKA 4GH8A 1DG8A 3KGYA 3RO9A 3FRAX 4XT8A 4XRBA 2LF1A 3FY9X 1IA4A 4KBNA 3EELA 1MVTA 2HXVA 3HJ3A 4ELBA 1RX9A 4PDJA 1KMSA 1BZFA 3JWMA 2FZIA 3IA5A 4IXED 1D1GA 3FYWX 4XECX 1LY4A 4M6KA 4X5IA 3K74A 5HUIA 4CD2A 4Q0EA 3F0BX 3GHVA 3QLXA 3K2HA 1DIUA 3E0BA 2W9HA 1RX6A 3TQ8A 1HFRA 1RX4A 4G8ZX 3SQYX 4PTJA 4FHBA 1AO8A 4IXFX 3DL6A 3CL9A 3F0UX 4H98A 1RE7A 1U71A 3FS6A 5HSUA 1RA2A 1S3VA 4M2XA 4ELFA 1RB2A 3S3VA 3I3RA 4Q6AA 4P3QA 2OIPA 3JSUA 4XT7A 2QK8A 1DR4A 3FQVA 8DFRA 4KJLA 3TQBA 2BLBA 3OCHA 1HFPA 1E26A 2W3MA 1BOZA 7DFRA 3DL5A 4FGGA 3QFXA 3NXVA 3ZPGA 4KAKA 4M6JA 1LUDA 3F8ZA 2JYBA 4QHVA 4KEBA 1DF7A 2GD9A 1RX7A 6DFRA 1RA1A 3CD2A 2G6VA 2L28A 1DR1A 2BLAA 3DAUA 1DHIA 1VDRA 4HA9A 4OR7A 1VJ3A 3FREX 5HT4A 5HQZA 1M7AA 5HT5A 3FQZA 1RG7A 4M7VA 4EJ1A 3FQCA 1JUVA 3IRMA 2W9TA 3OAFA 1PDBA 1RX8A 2W3BA 1JOLA 1DRAA 4QJZD 3ZPCA 4DPHA 5DXVA 4DPDA 3L3RA 1S3YA 1DG5A 4KNEA 2D0KA 3SRRX 1DR6A 5ECCA 1DR2A 3JW5A 1KMVA 4HOFA 2FZJA 3NXXA 2C2SA 1MVSA 4H95A 5CC9A 4Q67A 2W9GA 3D80A 4ELHA 4ELGA 4DDRA 3FQOA 3SRQX 1DYHA 2D5NA 3SRUX 3NZCX 1U70A 1DYRA 5HVEA 3GYFA 1SEJA 1J3JA 4KD7A 3ROAA 1J3IA 1S3UA 4RGCA 4NX6A 3QL0A 4KLXA 2CD2A 3EEMA 3LG4A 2KGKA 4KJKA 4QLFA 5JA3A 1DLRA 1DISA 4X5GA 4QLEA 4LAEX 3NXOA 3NXTA 1DLSA 1S3WA 4P3RA 4H97A 4QLGA 3GHWA 3CSEA 3QGTA 3TD8A 4KFJA 3F0VX 1OHKA 1ZDRA 3FL8A 3QLRA 3KFYA 2ANOA 2H2QA 1IA1A 1U72A 3QLSA 4XT5A 1DHFA 4QI9A 1LY3A 3QYOA 1DRFA 3FRDX 3IROA 2C2TA 4KL9A 5DFRA 4NX7A 4KYAA 1M79A 1DG7A 4PSTA 3NZ6X 4XE6X 1M78A 1RX2A 3F0SX 4TU5X 4KY8A 5CCCA 4P68A 3NZDA 1RB3A 4M6LA 3R33A 4HOGA 3FQ0A 3I8AX 3KJSA 4I13A 1JOMA 1RA3A 1DREA 3FRBX 2XW7A 3KY8A 3NXRA 1DYIA 3NZBX 3SA1A 1DDRA 3DFRA 1RH3A 3JVXA 1QZFA 4LAHX 1PD8A 2W3VA 3F91A 5HF0X 3FQFA 3M08A 1CD2A 3NXYA 1DYJA 3JTWA 3QG2A 2OBCA 4KM2A 4KY4A 1TDRA 3EIGA 5HQYA 4G95A 3D84X 4FGHA 4IXGX 4PSYA 3CLBA 3NTZA 3INVA 1RX5A 4LEKX 2HM9A 3UM6A 3F0XX 4HA7A 3IA4A 1AI9A 3EEKA 2AZNA 4OSGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DRB A;  2BL9 A;  3QLY A;  3SH2 A;  3KJR A;  3S9U A;  5HF2 X;  3SA2 A;  4X5F A;  2INQ A;  1DR5 A;  1KLK A;  1IA2 A;  4XT4 A;  3S7A A;  4PTH A;  3Q1H A;  3GI2 A;  3VCO A;  3F8Y A;  3SR5 X;  4HOE A;  3QLZ A;  3FYV X;  4H96 A;  1CZ3 A;  2ZZA A;  3UM5 A;  4P66 A;  3EX8 A;  5E8Q A;  4ELE A;  3JWK A;  1RD7 A;  3SRS X;  1DAJ A;  5FDA A;  5ECX A;  1DRH A;  2W3A A;  3IX9 A;  3QLW A;  4X5H A;  3SAI A;  1RC4 A;  4KM0 A;  3M09 A;  3NZA X;  1DHJ A;  3JW3 A;  5U27 A;  3UM8 A;  2CIG A;  2P4G A;  1AOE A;  4DP3 A;  3F0Q X;  5HPB A;  3QYL A;  1RX3 A;  2BLC A;  2DRC A;  1OHJ A;  4PSS A;  3NRR A;  4EIG A;  3FL9 A;  3NU0 A;  3FRF X;  2W9S A;  4EIL A;  3NZ9 X;  1HFQ A;  2O7P A;  3JWF A;  1RA9 A;  3GHC A;  1DDS A;  2W3W A;  5U26 A;  2ANQ A;  3QL3 A;  1RF7 A;  1J3K A;  3DAT A;  5HVB A;  3K45 A;  2FZH A;  3TQA A;  3TQ9 A;  2B3Z A;  1YHO A;  1PD9 A;  4EIZ A;  3N0H A;  5JG0 X;  1RA8 A;  4KJJ A;  4XT6 A;  3K47 A;  1IA3 A;  3JWC A;  3SGY A;  3IRN A;  3SRW X;  4Q0D A;  1DR7 A;  4DFR A;  4LAG X;  4QJC A;  2DHF A;  3RG9 A;  1DR3 A;  2HQP A;  3HBB A;  4X5J A;  5HSR A;  2ITH A;  3EEJ A;  4G3M A;  4M7U A;  5EAJ A;  5HI6 A;  3DG8 A;  4I1N A;  3DGA A;  3FY8 X;  1RX1 A;  3DRC A;  4ECK A;  4GH8 A;  1DG8 A;  3KGY A;  3RO9 A;  3FRA X;  4XT8 A;  4XRB A;  2LF1 A;  3FY9 X;  1IA4 A;  4KBN A;  3EEL A;  1MVT A;  2HXV A;  3HJ3 A;  4ELB A;  1RX9 A;  4PDJ A;  1KMS A;  1BZF A;  3JWM A;  2FZI A;  3IA5 A;  4IXE D;  1D1G A;  3FYW X;  4XEC X;  1LY4 A;  4M6K A;  4X5I A;  3K74 A;  5HUI A;  4CD2 A;  4Q0E A;  3F0B X;  3GHV A;  3QLX A;  3K2H A;  1DIU A;  3E0B A;  2W9H A;  1RX6 A;  3TQ8 A;  1HFR A;  1RX4 A;  4G8Z X;  3SQY X;  4PTJ A;  4FHB A;  1AO8 A;  4IXF X;  3DL6 A;  3CL9 A;  3F0U X;  4H98 A;  1RE7 A;  1U71 A;  3FS6 A;  5HSU A;  1RA2 A;  1S3V A;  4M2X A;  4ELF A;  1RB2 A;  3S3V A;  3I3R A;  4Q6A A;  4P3Q A;  2OIP A;  3JSU A;  4XT7 A;  2QK8 A;  1DR4 A;  3FQV A;  8DFR A;  4KJL A;  3TQB A;  2BLB A;  3OCH A;  1HFP A;  1E26 A;  2W3M A;  1BOZ A;  7DFR A;  3DL5 A;  4FGG A;  3QFX A;  3NXV A;  3ZPG A;  4KAK A;  4M6J A;  1LUD A;  3F8Z A;  2JYB A;  4QHV A;  4KEB A;  1DF7 A;  2GD9 A;  1RX7 A;  6DFR A;  1RA1 A;  3CD2 A;  2G6V A;  2L28 A;  1DR1 A;  2BLA A;  3DAU A;  1DHI A;  1VDR A;  4HA9 A;  4OR7 A;  1VJ3 A;  3FRE X;  5HT4 A;  5HQZ A;  1M7A A;  5HT5 A;  3FQZ A;  1RG7 A;  4M7V A;  4EJ1 A;  3FQC A;  1JUV A;  3IRM A;  2W9T A;  3OAF A;  1PDB A;  1RX8 A;  2W3B A;  1JOL A;  1DRA A;  4QJZ D;  3ZPC A;  4DPH A;  5DXV A;  4DPD A;  3L3R A;  1S3Y A;  1DG5 A;  4KNE A;  2D0K A;  3SRR X;  1DR6 A;  5ECC A;  1DR2 A;  3JW5 A;  1KMV A;  4HOF A;  2FZJ A;  3NXX A;  2C2S A;  1MVS A;  4H95 A;  5CC9 A;  4Q67 A;  2W9G A;  3D80 A;  4ELH A;  4ELG A;  4DDR A;  3FQO A;  3SRQ X;  1DYH A;  2D5N A;  3SRU X;  3NZC X;  1U70 A;  1DYR A;  5HVE A;  3GYF A;  1SEJ A;  1J3J A;  4KD7 A;  3ROA A;  1J3I A;  1S3U A;  4RGC A;  4NX6 A;  3QL0 A;  4KLX A;  2CD2 A;  3EEM A;  3LG4 A;  2KGK A;  4KJK A;  4QLF A;  5JA3 A;  1DLR A;  1DIS A;  4X5G A;  4QLE A;  4LAE X;  3NXO A;  3NXT A;  1DLS A;  1S3W A;  4P3R A;  4H97 A;  4QLG A;  3GHW A;  3CSE A;  3QGT A;  3TD8 A;  4KFJ A;  3F0V X;  1OHK A;  1ZDR A;  3FL8 A;  3QLR A;  3KFY A;  2ANO A;  2H2Q A;  1IA1 A;  1U72 A;  3QLS A;  4XT5 A;  1DHF A;  4QI9 A;  1LY3 A;  3QYO A;  1DRF A;  3FRD X;  3IRO A;  2C2T A;  4KL9 A;  5DFR A;  4NX7 A;  4KYA A;  1M79 A;  1DG7 A;  4PST A;  3NZ6 X;  4XE6 X;  1M78 A;  1RX2 A;  3F0S X;  4TU5 X;  4KY8 A;  5CCC A;  4P68 A;  3NZD A;  1RB3 A;  4M6L A;  3R33 A;  4HOG A;  3FQ0 A;  3I8A X;  3KJS A;  4I13 A;  1JOM A;  1RA3 A;  1DRE A;  3FRB X;  2XW7 A;  3KY8 A;  3NXR A;  1DYI A;  3NZB X;  3SA1 A;  1DDR A;  3DFR A;  1RH3 A;  3JVX A;  1QZF A;  4LAH X;  1PD8 A;  2W3V A;  3F91 A;  5HF0 X;  3FQF A;  3M08 A;  1CD2 A;  3NXY A;  1DYJ A;  3JTW A;  3QG2 A;  2OBC A;  4KM2 A;  4KY4 A;  1TDR A;  3EIG A;  5HQY A;  4G95 A;  3D84 X;  4FGH A;  4IXG X;  4PSY A;  3CLB A;  3NTZ A;  3INV A;  1RX5 A;  4LEK X;  2HM9 A;  3UM6 A;  3F0X X;  4HA7 A;  3IA4 A;  1AI9 A;  3EEK A;  2AZN A;  4OSG A; 
#chains in the Genus database with same CATH topology
 1DRB A;  2BL9 A;  3QLY A;  3SH2 A;  3KJR A;  3S9U A;  5HF2 X;  3SA2 A;  4X5F A;  2INQ A;  1DR5 A;  1KLK A;  1IA2 A;  4XT4 A;  3S7A A;  4PTH A;  3Q1H A;  3GI2 A;  3VCO A;  3F8Y A;  3SR5 X;  4HOE A;  3QLZ A;  3FYV X;  4H96 A;  1CZ3 A;  2ZZA A;  3UM5 A;  4P66 A;  3EX8 A;  5E8Q A;  4ELE A;  3JWK A;  1RD7 A;  3SRS X;  1DAJ A;  5FDA A;  5ECX A;  1DRH A;  2W3A A;  3IX9 A;  3QLW A;  4X5H A;  3SAI A;  1RC4 A;  4KM0 A;  3M09 A;  3NZA X;  1DHJ A;  3JW3 A;  5U27 A;  3UM8 A;  2CIG A;  2P4G A;  1AOE A;  4DP3 A;  3F0Q X;  5HPB A;  3QYL A;  1RX3 A;  2BLC A;  2DRC A;  1OHJ A;  4PSS A;  3NRR A;  4EIG A;  3FL9 A;  3NU0 A;  3FRF X;  2W9S A;  4EIL A;  3NZ9 X;  1HFQ A;  2O7P A;  3JWF A;  1RA9 A;  3GHC A;  1DDS A;  2W3W A;  5U26 A;  2ANQ A;  3QL3 A;  1RF7 A;  1J3K A;  3DAT A;  5HVB A;  3K45 A;  2FZH A;  3TQA A;  3TQ9 A;  2B3Z A;  1YHO A;  1PD9 A;  4EIZ A;  3N0H A;  5JG0 X;  1RA8 A;  4KJJ A;  4XT6 A;  3K47 A;  1IA3 A;  3JWC A;  3SGY A;  3IRN A;  3SRW X;  4Q0D A;  1DR7 A;  4DFR A;  4LAG X;  4QJC A;  2DHF A;  3RG9 A;  1DR3 A;  2HQP A;  3HBB A;  4X5J A;  5HSR A;  2ITH A;  3EEJ A;  4G3M A;  4M7U A;  5EAJ A;  5HI6 A;  3DG8 A;  4I1N A;  3DGA A;  3FY8 X;  1RX1 A;  3DRC A;  4ECK A;  4GH8 A;  1DG8 A;  3KGY A;  3RO9 A;  3FRA X;  4XT8 A;  4XRB A;  2LF1 A;  3FY9 X;  1IA4 A;  4KBN A;  3EEL A;  1MVT A;  2HXV A;  3HJ3 A;  4ELB A;  1RX9 A;  4PDJ A;  1KMS A;  1BZF A;  3JWM A;  2FZI A;  3IA5 A;  4IXE D;  1D1G A;  3FYW X;  4XEC X;  1LY4 A;  4M6K A;  4X5I A;  3K74 A;  5HUI A;  4CD2 A;  4Q0E A;  3F0B X;  3GHV A;  3QLX A;  3K2H A;  1DIU A;  3E0B A;  2W9H A;  1RX6 A;  3TQ8 A;  1HFR A;  1RX4 A;  4G8Z X;  3SQY X;  4PTJ A;  4FHB A;  1AO8 A;  4IXF X;  3DL6 A;  3CL9 A;  3F0U X;  4H98 A;  1RE7 A;  1U71 A;  3FS6 A;  5HSU A;  1RA2 A;  1S3V A;  4M2X A;  4ELF A;  1RB2 A;  3S3V A;  3I3R A;  4Q6A A;  4P3Q A;  2OIP A;  3JSU A;  4XT7 A;  2QK8 A;  1DR4 A;  3FQV A;  8DFR A;  4KJL A;  3TQB A;  2BLB A;  3OCH A;  1HFP A;  1E26 A;  2W3M A;  1BOZ A;  7DFR A;  3DL5 A;  4FGG A;  3QFX A;  3NXV A;  3ZPG A;  4KAK A;  4M6J A;  1LUD A;  3F8Z A;  2JYB A;  4QHV A;  4KEB A;  1DF7 A;  2GD9 A;  1RX7 A;  6DFR A;  1RA1 A;  3CD2 A;  2G6V A;  2L28 A;  1DR1 A;  2BLA A;  3DAU A;  1DHI A;  1VDR A;  4HA9 A;  4OR7 A;  1VJ3 A;  3FRE X;  5HT4 A;  5HQZ A;  1M7A A;  5HT5 A;  3FQZ A;  1RG7 A;  4M7V A;  4EJ1 A;  3FQC A;  1JUV A;  3IRM A;  2W9T A;  3OAF A;  1PDB A;  1RX8 A;  2W3B A;  1JOL A;  1DRA A;  4QJZ D;  3ZPC A;  4DPH A;  5DXV A;  4DPD A;  3L3R A;  1S3Y A;  1DG5 A;  4KNE A;  2D0K A;  3SRR X;  1DR6 A;  5ECC A;  1DR2 A;  3JW5 A;  1KMV A;  4HOF A;  2FZJ A;  3NXX A;  2C2S A;  1MVS A;  4H95 A;  5CC9 A;  4Q67 A;  2W9G A;  3D80 A;  4ELH A;  4ELG A;  4DDR A;  3FQO A;  3SRQ X;  1DYH A;  2D5N A;  3SRU X;  3NZC X;  1U70 A;  1DYR A;  5HVE A;  3GYF A;  1SEJ A;  1J3J A;  4KD7 A;  3ROA A;  1J3I A;  1S3U A;  4RGC A;  4NX6 A;  3QL0 A;  4KLX A;  2CD2 A;  3EEM A;  3LG4 A;  2KGK A;  4KJK A;  4QLF A;  5JA3 A;  1DLR A;  1DIS A;  4X5G A;  4QLE A;  4LAE X;  3NXO A;  3NXT A;  1DLS A;  1S3W A;  4P3R A;  4H97 A;  4QLG A;  3GHW A;  3CSE A;  3QGT A;  3TD8 A;  4KFJ A;  3F0V X;  1OHK A;  1ZDR A;  3FL8 A;  3QLR A;  3KFY A;  2ANO A;  2H2Q A;  1IA1 A;  1U72 A;  3QLS A;  4XT5 A;  1DHF A;  4QI9 A;  1LY3 A;  3QYO A;  1DRF A;  3FRD X;  3IRO A;  2C2T A;  4KL9 A;  5DFR A;  4NX7 A;  4KYA A;  1M79 A;  1DG7 A;  4PST A;  3NZ6 X;  4XE6 X;  1M78 A;  1RX2 A;  3F0S X;  4TU5 X;  4KY8 A;  5CCC A;  4P68 A;  3NZD A;  1RB3 A;  4M6L A;  3R33 A;  4HOG A;  3FQ0 A;  3I8A X;  3KJS A;  4I13 A;  1JOM A;  1RA3 A;  1DRE A;  3FRB X;  2XW7 A;  3KY8 A;  3NXR A;  1DYI A;  3NZB X;  3SA1 A;  1DDR A;  3DFR A;  1RH3 A;  3JVX A;  1QZF A;  4LAH X;  1PD8 A;  2W3V A;  3F91 A;  5HF0 X;  3FQF A;  3M08 A;  1CD2 A;  3NXY A;  1DYJ A;  3JTW A;  3QG2 A;  2OBC A;  4KM2 A;  4KY4 A;  1TDR A;  3EIG A;  5HQY A;  4G95 A;  3D84 X;  4FGH A;  4IXG X;  4PSY A;  3CLB A;  3NTZ A;  3INV A;  1RX5 A;  4LEK X;  2HM9 A;  3UM6 A;  3F0X X;  4HA7 A;  3IA4 A;  1AI9 A;  3EEK A;  2AZN A;  4OSG A; 
#chains in the Genus database with same CATH homology
 1DRB A;  2BL9 A;  3QLY A;  3SH2 A;  3KJR A;  3S9U A;  5HF2 X;  3SA2 A;  4X5F A;  2INQ A;  1DR5 A;  1KLK A;  1IA2 A;  4XT4 A;  3S7A A;  4PTH A;  3Q1H A;  3GI2 A;  3VCO A;  3F8Y A;  3SR5 X;  4HOE A;  3QLZ A;  3FYV X;  4H96 A;  1CZ3 A;  2ZZA A;  3UM5 A;  4P66 A;  3EX8 A;  5E8Q A;  4ELE A;  3JWK A;  1RD7 A;  3SRS X;  1DAJ A;  5FDA A;  5ECX A;  1DRH A;  2W3A A;  3IX9 A;  3QLW A;  4X5H A;  3SAI A;  1RC4 A;  4KM0 A;  3M09 A;  3NZA X;  1DHJ A;  3JW3 A;  5U27 A;  3UM8 A;  2CIG A;  2P4G A;  1AOE A;  4DP3 A;  3F0Q X;  5HPB A;  3QYL A;  1RX3 A;  2BLC A;  2DRC A;  1OHJ A;  4PSS A;  3NRR A;  4EIG A;  3FL9 A;  3NU0 A;  3FRF X;  2W9S A;  4EIL A;  3NZ9 X;  1HFQ A;  2O7P A;  3JWF A;  1RA9 A;  3GHC A;  1DDS A;  2W3W A;  5U26 A;  2ANQ A;  3QL3 A;  1RF7 A;  1J3K A;  3DAT A;  5HVB A;  3K45 A;  2FZH A;  3TQA A;  3TQ9 A;  2B3Z A;  1YHO A;  1PD9 A;  4EIZ A;  3N0H A;  5JG0 X;  1RA8 A;  4KJJ A;  4XT6 A;  3K47 A;  1IA3 A;  3JWC A;  3SGY A;  3IRN A;  3SRW X;  4Q0D A;  1DR7 A;  4DFR A;  4LAG X;  4QJC A;  2DHF A;  3RG9 A;  1DR3 A;  2HQP A;  3HBB A;  4X5J A;  5HSR A;  2ITH A;  3EEJ A;  4G3M A;  4M7U A;  5EAJ A;  5HI6 A;  3DG8 A;  4I1N A;  3DGA A;  3FY8 X;  1RX1 A;  3DRC A;  4ECK A;  4GH8 A;  1DG8 A;  3KGY A;  3RO9 A;  3FRA X;  4XT8 A;  4XRB A;  2LF1 A;  3FY9 X;  1IA4 A;  4KBN A;  3EEL A;  1MVT A;  2HXV A;  3HJ3 A;  4ELB A;  1RX9 A;  4PDJ A;  1KMS A;  1BZF A;  3JWM A;  2FZI A;  3IA5 A;  4IXE D;  1D1G A;  3FYW X;  4XEC X;  1LY4 A;  4M6K A;  4X5I A;  3K74 A;  5HUI A;  4CD2 A;  4Q0E A;  3F0B X;  3GHV A;  3QLX A;  3K2H A;  1DIU A;  3E0B A;  2W9H A;  1RX6 A;  3TQ8 A;  1HFR A;  1RX4 A;  4G8Z X;  3SQY X;  4PTJ A;  4FHB A;  1AO8 A;  4IXF X;  3DL6 A;  3CL9 A;  3F0U X;  4H98 A;  1RE7 A;  1U71 A;  3FS6 A;  5HSU A;  1RA2 A;  1S3V A;  4M2X A;  4ELF A;  1RB2 A;  3S3V A;  3I3R A;  4Q6A A;  4P3Q A;  2OIP A;  3JSU A;  4XT7 A;  2QK8 A;  1DR4 A;  3FQV A;  8DFR A;  4KJL A;  3TQB A;  2BLB A;  3OCH A;  1HFP A;  1E26 A;  2W3M A;  1BOZ A;  7DFR A;  3DL5 A;  4FGG A;  3QFX A;  3NXV A;  3ZPG A;  4KAK A;  4M6J A;  1LUD A;  3F8Z A;  2JYB A;  4QHV A;  4KEB A;  1DF7 A;  2GD9 A;  1RX7 A;  6DFR A;  1RA1 A;  3CD2 A;  2G6V A;  2L28 A;  1DR1 A;  2BLA A;  3DAU A;  1DHI A;  1VDR A;  4HA9 A;  4OR7 A;  1VJ3 A;  3FRE X;  5HT4 A;  5HQZ A;  1M7A A;  5HT5 A;  3FQZ A;  1RG7 A;  4M7V A;  4EJ1 A;  3FQC A;  1JUV A;  3IRM A;  2W9T A;  3OAF A;  1PDB A;  1RX8 A;  2W3B A;  1JOL A;  1DRA A;  4QJZ D;  3ZPC A;  4DPH A;  5DXV A;  4DPD A;  3L3R A;  1S3Y A;  1DG5 A;  4KNE A;  2D0K A;  3SRR X;  1DR6 A;  5ECC A;  1DR2 A;  3JW5 A;  1KMV A;  4HOF A;  2FZJ A;  3NXX A;  2C2S A;  1MVS A;  4H95 A;  5CC9 A;  4Q67 A;  2W9G A;  3D80 A;  4ELH A;  4ELG A;  4DDR A;  3FQO A;  3SRQ X;  1DYH A;  2D5N A;  3SRU X;  3NZC X;  1U70 A;  1DYR A;  5HVE A;  3GYF A;  1SEJ A;  1J3J A;  4KD7 A;  3ROA A;  1J3I A;  1S3U A;  4RGC A;  4NX6 A;  3QL0 A;  4KLX A;  2CD2 A;  3EEM A;  3LG4 A;  2KGK A;  4KJK A;  4QLF A;  5JA3 A;  1DLR A;  1DIS A;  4X5G A;  4QLE A;  4LAE X;  3NXO A;  3NXT A;  1DLS A;  1S3W A;  4P3R A;  4H97 A;  4QLG A;  3GHW A;  3CSE A;  3QGT A;  3TD8 A;  4KFJ A;  3F0V X;  1OHK A;  1ZDR A;  3FL8 A;  3QLR A;  3KFY A;  2ANO A;  2H2Q A;  1IA1 A;  1U72 A;  3QLS A;  4XT5 A;  1DHF A;  4QI9 A;  1LY3 A;  3QYO A;  1DRF A;  3FRD X;  3IRO A;  2C2T A;  4KL9 A;  5DFR A;  4NX7 A;  4KYA A;  1M79 A;  1DG7 A;  4PST A;  3NZ6 X;  4XE6 X;  1M78 A;  1RX2 A;  3F0S X;  4TU5 X;  4KY8 A;  5CCC A;  4P68 A;  3NZD A;  1RB3 A;  4M6L A;  3R33 A;  4HOG A;  3FQ0 A;  3I8A X;  3KJS A;  4I13 A;  1JOM A;  1RA3 A;  1DRE A;  3FRB X;  2XW7 A;  3KY8 A;  3NXR A;  1DYI A;  3NZB X;  3SA1 A;  1DDR A;  3DFR A;  1RH3 A;  3JVX A;  1QZF A;  4LAH X;  1PD8 A;  2W3V A;  3F91 A;  5HF0 X;  3FQF A;  3M08 A;  1CD2 A;  3NXY A;  1DYJ A;  3JTW A;  3QG2 A;  2OBC A;  4KM2 A;  4KY4 A;  1TDR A;  3EIG A;  5HQY A;  4G95 A;  3D84 X;  4FGH A;  4IXG X;  4PSY A;  3CLB A;  3NTZ A;  3INV A;  1RX5 A;  4LEK X;  2HM9 A;  3UM6 A;  3F0X X;  4HA7 A;  3IA4 A;  1AI9 A;  3EEK A;  2AZN A;  4OSG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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