3FQZA

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus rf122
molecule keywords Trimethoprim-sensitive dihydrofolate reductase
total genus 40
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-01-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3fqzA00
3EEMA 2HM9A 1VJ3A 2DHFA 3JSUA 3F91A 4G95A 4KJLA 1DYIA 1DR4A 4KAKA 1RB2A 4H96A 4X5HA 2W3AA 3FQOA 1RD7A 2ZZAA 3FQZA 5HT5A 1PD8A 1RC4A 3KJRA 3JWFA 1RX7A 2ANQA 1D1GA 3N0HA 1LUDA 3DAUA 5DXVA 3ZPGA 4X5FA 3FYWX 3SR5X 3CD2A 2W3VA 2HQPA 3F0BX 3NXYA 4OSGA 2BLBA 4Q6AA 1RX6A 1PDBA 3IROA 4P68A 4ELHA 1RE7A 3E0BA 1VDRA 3FRFX 4HOFA 2C2SA 4X5JA 5DFRA 4EIZA 3HJ3A 3CL9A 2W9HA 1HFRA 4XT6A 1RA3A 5E8QA 3NRRA 5HUIA 4FGHA 1HFPA 3L3RA 3IRNA 4P3QA 2FZHA 3QLWA 3M09A 1U70A 4QHVA 3DGAA 3R33A 3IRMA 3K2HA 5HQZA 1LY3A 7DFRA 4M6LA 2LF1A 3TQBA 3JWMA 3FY8X 1DRBA 3FRAX 4XRBA 1DR2A 3GHVA 1DR7A 1DISA 4HOEA 3IX9A 4XE6X 4KJKA 1RX3A 5ECCA 2FZJA 2ITHA 4XT7A 5HT4A 2CIGA 4FGGA 3EELA 1RF7A 4G3MA 1DREA 3FQ0A 4EIGA 1CZ3A 1KMSA 3GHWA 4DPHA 4HOGA 5FDAA 3S7AA 2W9GA 3QLRA 4KY8A 5HQYA 4ECKA 1CD2A 2P4GA 4KYAA 4IXFX 3DL6A 5JG0X 1HFQA 4QI9A 3RO9A 4RGCA 4KD7A 4XT5A 3JWKA 3Q1HA 3QG2A 4G8ZX 3DFRA 3JW3A 3GI2A 1AO8A 4KNEA 4XECX 4I13A 3SRSX 3FL9A 1DG5A 1DLSA 2D0KA 3DG8A 3S3VA 4H95A 2W3MA 3TQAA 4ELGA 4OR7A 4QLFA 4XT8A 3INVA 3TQ8A 3JVXA 1S3UA 4DPDA 3UM5A 3KJSA 3NXTA 3JWCA 3F0SX 5HF2X 2W3BA 5EAJA 5U26A 4HA9A 5HPBA 1MVTA 5HSRA 2INQA 3IA4A 3ROAA 2CD2A 4KLXA 3NXXA 3QYOA 3NZ6X 2W9TA 1RA1A 1BOZA 3IA5A 1OHJA 1LY4A 1DYJA 3D80A 5JA3A 2C2TA 2BLAA 4KBNA 1RX4A 4TU5X 3FS6A 4QLGA 1DDRA 3JW5A 1DYHA 3UM6A 1RA8A 3K74A 2AZNA 1S3VA 4KM2A 3JTWA 4X5IA 3QL3A 3D84X 3NXVA 3GYFA 1TDRA 1DR5A 2BL9A 4LAGX 4HA7A 4LAEX 4PSSA 2D5NA 3SGYA 1DHJA 2XW7A 3EEJA 2W3WA 3SAIA 5U27A 3FQFA 4DFRA 2ANOA 2W9SA 4P66A 1KLKA 4GH8A 1U71A 4Q0EA 2B3ZA 1DG8A 1J3KA 3OCHA 3SRUX 1DRAA 4EILA 3CSEA 3KY8A 4KM0A 1RA9A 1DF7A 4M7VA 3K45A 3SA2A 1MVSA 3KGYA 2O7PA 4CD2A 4PDJA 3EX8A 5CC9A 3RG9A 3GHCA 3F0VX 5ECXA 3ZPCA 3QYLA 1RG7A 3SRQX 1DRFA 1DR6A 1DYRA 1JOMA 1S3YA 1DR1A 3NZDA 3UM8A 1ZDRA 3VCOA 2DRCA 4KFJA 2OIPA 1M78A 2JYBA 3NTZA 3F8YA 3SRRX 4M6JA 3SA1A 1J3JA 2FZIA 3NXRA 3SH2A 4FHBA 1RX1A 3KFYA 3QGTA 3F8ZA 6DFRA 4P3RA 1RX5A 3QLZA 4KJJA 1DG7A 1M79A 5HSUA 1DLRA 4IXED 3QLXA 1DRHA 4M7UA 3SQYX 3F0XX 4M2XA 1RH3A 1DAJA 3FL8A 3FREX 3NZAX 4NX7A 4ELEA 1KMVA 3QFXA 4KEBA 4M6KA 3S9UA 4ELBA 4KL9A 2KGKA 8DFRA 3EIGA 1RB3A 3LG4A 3SRWX 4QJZD 2OBCA 1IA2A 4H97A 3M08A 3I8AX 4EJ1A 1S3WA 4QJCA 4PTHA 2H2QA 1OHKA 3FRDX 3F0UX 4LAHX 2BLCA 3FQCA 4XT4A 4Q67A 1J3IA 1BZFA 3F0QX 3TD8A 4PSYA 3QLSA 1YHOA 2L28A 3NZBX 4LEKX 1E26A 1IA4A 1IA1A 2GD9A 1DHFA 1RX9A 3CLBA 5CCCA 3FY9X 4ELFA 1AOEA 3QL0A 3NZCX 4DP3A 1RA2A 4PTJA 2HXVA 3FYVX 5HVEA 4H98A 4QLEA 3HBBA 1IA3A 1DIUA 3EEKA 3QLYA 1DHIA 3NZ9X 4IXGX 2G6VA 3DRCA 1RX2A 1AI9A 3TQ9A 1PD9A 1DDSA 1M7AA 1SEJA 5HF0X 4X5GA 3NXOA 3OAFA 4I1NA 4DDRA 2QK8A 3NU0A 5HVBA 4KY4A 1JOLA 1DR3A 4NX6A 3FQVA 3DATA 1RX8A 1U72A 3DL5A 4PSTA 4Q0DA 3FRBX 5HI6A 3I3RA 1JUVA 1QZFA 3K47A
chains in the Genus database with same CATH superfamily
3EEMA 2HM9A 1VJ3A 2DHFA 3JSUA 3F91A 4G95A 4KJLA 1DYIA 1DR4A 4KAKA 1RB2A 4H96A 4X5HA 2W3AA 3FQOA 1RD7A 2ZZAA 3FQZA 5HT5A 1PD8A 1RC4A 3KJRA 3JWFA 1RX7A 2ANQA 1D1GA 3N0HA 1LUDA 3DAUA 5DXVA 3ZPGA 4X5FA 3FYWX 3SR5X 3CD2A 2W3VA 2HQPA 3F0BX 3NXYA 4OSGA 2BLBA 4Q6AA 1RX6A 1PDBA 3IROA 4P68A 4ELHA 1RE7A 3E0BA 1VDRA 3FRFX 4HOFA 2C2SA 4X5JA 5DFRA 4EIZA 3HJ3A 3CL9A 2W9HA 1HFRA 4XT6A 1RA3A 5E8QA 3NRRA 5HUIA 4FGHA 1HFPA 3L3RA 3IRNA 4P3QA 2FZHA 3QLWA 3M09A 1U70A 4QHVA 3DGAA 3R33A 3IRMA 3K2HA 5HQZA 1LY3A 7DFRA 4M6LA 2LF1A 3TQBA 3JWMA 3FY8X 1DRBA 3FRAX 4XRBA 1DR2A 3GHVA 1DR7A 1DISA 4HOEA 3IX9A 4XE6X 4KJKA 1RX3A 5ECCA 2FZJA 2ITHA 4XT7A 5HT4A 2CIGA 4FGGA 3EELA 1RF7A 4G3MA 1DREA 3FQ0A 4EIGA 1CZ3A 1KMSA 3GHWA 4DPHA 4HOGA 5FDAA 3S7AA 2W9GA 3QLRA 4KY8A 5HQYA 4ECKA 1CD2A 2P4GA 4KYAA 4IXFX 3DL6A 5JG0X 1HFQA 4QI9A 3RO9A 4RGCA 4KD7A 4XT5A 3JWKA 3Q1HA 3QG2A 4G8ZX 3DFRA 3JW3A 3GI2A 1AO8A 4KNEA 4XECX 4I13A 3SRSX 3FL9A 1DG5A 1DLSA 2D0KA 3DG8A 3S3VA 4H95A 2W3MA 3TQAA 4ELGA 4OR7A 4QLFA 4XT8A 3INVA 3TQ8A 3JVXA 1S3UA 4DPDA 3UM5A 3KJSA 3NXTA 3JWCA 3F0SX 5HF2X 2W3BA 5EAJA 5U26A 4HA9A 5HPBA 1MVTA 5HSRA 2INQA 3IA4A 3ROAA 2CD2A 4KLXA 3NXXA 3QYOA 3NZ6X 2W9TA 1RA1A 1BOZA 3IA5A 1OHJA 1LY4A 1DYJA 3D80A 5JA3A 2C2TA 2BLAA 4KBNA 1RX4A 4TU5X 3FS6A 4QLGA 1DDRA 3JW5A 1DYHA 3UM6A 1RA8A 3K74A 2AZNA 1S3VA 4KM2A 3JTWA 4X5IA 3QL3A 3D84X 3NXVA 3GYFA 1TDRA 1DR5A 2BL9A 4LAGX 4HA7A 4LAEX 4PSSA 2D5NA 3SGYA 1DHJA 2XW7A 3EEJA 2W3WA 3SAIA 5U27A 3FQFA 4DFRA 2ANOA 2W9SA 4P66A 1KLKA 4GH8A 1U71A 4Q0EA 2B3ZA 1DG8A 1J3KA 3OCHA 3SRUX 1DRAA 4EILA 3CSEA 3KY8A 4KM0A 1RA9A 1DF7A 4M7VA 3K45A 3SA2A 1MVSA 3KGYA 2O7PA 4CD2A 4PDJA 3EX8A 5CC9A 3RG9A 3GHCA 3F0VX 5ECXA 3ZPCA 3QYLA 1RG7A 3SRQX 1DRFA 1DR6A 1DYRA 1JOMA 1S3YA 1DR1A 3NZDA 3UM8A 1ZDRA 3VCOA 2DRCA 4KFJA 2OIPA 1M78A 2JYBA 3NTZA 3F8YA 3SRRX 4M6JA 3SA1A 1J3JA 2FZIA 3NXRA 3SH2A 4FHBA 1RX1A 3KFYA 3QGTA 3F8ZA 6DFRA 4P3RA 1RX5A 3QLZA 4KJJA 1DG7A 1M79A 5HSUA 1DLRA 4IXED 3QLXA 1DRHA 4M7UA 3SQYX 3F0XX 4M2XA 1RH3A 1DAJA 3FL8A 3FREX 3NZAX 4NX7A 4ELEA 1KMVA 3QFXA 4KEBA 4M6KA 3S9UA 4ELBA 4KL9A 2KGKA 8DFRA 3EIGA 1RB3A 3LG4A 3SRWX 4QJZD 2OBCA 1IA2A 4H97A 3M08A 3I8AX 4EJ1A 1S3WA 4QJCA 4PTHA 2H2QA 1OHKA 3FRDX 3F0UX 4LAHX 2BLCA 3FQCA 4XT4A 4Q67A 1J3IA 1BZFA 3F0QX 3TD8A 4PSYA 3QLSA 1YHOA 2L28A 3NZBX 4LEKX 1E26A 1IA4A 1IA1A 2GD9A 1DHFA 1RX9A 3CLBA 5CCCA 3FY9X 4ELFA 1AOEA 3QL0A 3NZCX 4DP3A 1RA2A 4PTJA 2HXVA 3FYVX 5HVEA 4H98A 4QLEA 3HBBA 1IA3A 1DIUA 3EEKA 3QLYA 1DHIA 3NZ9X 4IXGX 2G6VA 3DRCA 1RX2A 1AI9A 3TQ9A 1PD9A 1DDSA 1M7AA 1SEJA 5HF0X 4X5GA 3NXOA 3OAFA 4I1NA 4DDRA 2QK8A 3NU0A 5HVBA 4KY4A 1JOLA 1DR3A 4NX6A 3FQVA 3DATA 1RX8A 1U72A 3DL5A 4PSTA 4Q0DA 3FRBX 5HI6A 3I3RA 1JUVA 1QZFA 3K47A
chains in the Genus database with same CATH topology
3EEMA 2HM9A 1VJ3A 2DHFA 3JSUA 3F91A 4G95A 4KJLA 1DYIA 1DR4A 4KAKA 1RB2A 4H96A 4X5HA 2W3AA 3FQOA 1RD7A 2ZZAA 3FQZA 5HT5A 1PD8A 1RC4A 3KJRA 3JWFA 1RX7A 2ANQA 1D1GA 3N0HA 1LUDA 3DAUA 5DXVA 3ZPGA 4X5FA 3FYWX 3SR5X 3CD2A 2W3VA 2HQPA 3F0BX 3NXYA 4OSGA 2BLBA 4Q6AA 1RX6A 1PDBA 3IROA 4P68A 4ELHA 1RE7A 3E0BA 1VDRA 3FRFX 4HOFA 2C2SA 4X5JA 5DFRA 4EIZA 3HJ3A 3CL9A 2W9HA 1HFRA 4XT6A 1RA3A 5E8QA 3NRRA 5HUIA 4FGHA 1HFPA 3L3RA 3IRNA 4P3QA 2FZHA 3QLWA 3M09A 1U70A 4QHVA 3DGAA 3R33A 3IRMA 3K2HA 5HQZA 1LY3A 7DFRA 4M6LA 2LF1A 3TQBA 3JWMA 3FY8X 1DRBA 3FRAX 4XRBA 1DR2A 3GHVA 1DR7A 1DISA 4HOEA 3IX9A 4XE6X 4KJKA 1RX3A 5ECCA 2FZJA 2ITHA 4XT7A 5HT4A 2CIGA 4FGGA 3EELA 1RF7A 4G3MA 1DREA 3FQ0A 4EIGA 1CZ3A 1KMSA 3GHWA 4DPHA 4HOGA 5FDAA 3S7AA 2W9GA 3QLRA 4KY8A 5HQYA 4ECKA 1CD2A 2P4GA 4KYAA 4IXFX 3DL6A 5JG0X 1HFQA 4QI9A 3RO9A 4RGCA 4KD7A 4XT5A 3JWKA 3Q1HA 3QG2A 4G8ZX 3DFRA 3JW3A 3GI2A 1AO8A 4KNEA 4XECX 4I13A 3SRSX 3FL9A 1DG5A 1DLSA 2D0KA 3DG8A 3S3VA 4H95A 2W3MA 3TQAA 4ELGA 4OR7A 4QLFA 4XT8A 3INVA 3TQ8A 3JVXA 1S3UA 4DPDA 3UM5A 3KJSA 3NXTA 3JWCA 3F0SX 5HF2X 2W3BA 5EAJA 5U26A 4HA9A 5HPBA 1MVTA 5HSRA 2INQA 3IA4A 3ROAA 2CD2A 4KLXA 3NXXA 3QYOA 3NZ6X 2W9TA 1RA1A 1BOZA 3IA5A 1OHJA 1LY4A 1DYJA 3D80A 5JA3A 2C2TA 2BLAA 4KBNA 1RX4A 4TU5X 3FS6A 4QLGA 1DDRA 3JW5A 1DYHA 3UM6A 1RA8A 3K74A 2AZNA 1S3VA 4KM2A 3JTWA 4X5IA 3QL3A 3D84X 3NXVA 3GYFA 1TDRA 1DR5A 2BL9A 4LAGX 4HA7A 4LAEX 4PSSA 2D5NA 3SGYA 1DHJA 2XW7A 3EEJA 2W3WA 3SAIA 5U27A 3FQFA 4DFRA 2ANOA 2W9SA 4P66A 1KLKA 4GH8A 1U71A 4Q0EA 2B3ZA 1DG8A 1J3KA 3OCHA 3SRUX 1DRAA 4EILA 3CSEA 3KY8A 4KM0A 1RA9A 1DF7A 4M7VA 3K45A 3SA2A 1MVSA 3KGYA 2O7PA 4CD2A 4PDJA 3EX8A 5CC9A 3RG9A 3GHCA 3F0VX 5ECXA 3ZPCA 3QYLA 1RG7A 3SRQX 1DRFA 1DR6A 1DYRA 1JOMA 1S3YA 1DR1A 3NZDA 3UM8A 1ZDRA 3VCOA 2DRCA 4KFJA 2OIPA 1M78A 2JYBA 3NTZA 3F8YA 3SRRX 4M6JA 3SA1A 1J3JA 2FZIA 3NXRA 3SH2A 4FHBA 1RX1A 3KFYA 3QGTA 3F8ZA 6DFRA 4P3RA 1RX5A 3QLZA 4KJJA 1DG7A 1M79A 5HSUA 1DLRA 4IXED 3QLXA 1DRHA 4M7UA 3SQYX 3F0XX 4M2XA 1RH3A 1DAJA 3FL8A 3FREX 3NZAX 4NX7A 4ELEA 1KMVA 3QFXA 4KEBA 4M6KA 3S9UA 4ELBA 4KL9A 2KGKA 8DFRA 3EIGA 1RB3A 3LG4A 3SRWX 4QJZD 2OBCA 1IA2A 4H97A 3M08A 3I8AX 4EJ1A 1S3WA 4QJCA 4PTHA 2H2QA 1OHKA 3FRDX 3F0UX 4LAHX 2BLCA 3FQCA 4XT4A 4Q67A 1J3IA 1BZFA 3F0QX 3TD8A 4PSYA 3QLSA 1YHOA 2L28A 3NZBX 4LEKX 1E26A 1IA4A 1IA1A 2GD9A 1DHFA 1RX9A 3CLBA 5CCCA 3FY9X 4ELFA 1AOEA 3QL0A 3NZCX 4DP3A 1RA2A 4PTJA 2HXVA 3FYVX 5HVEA 4H98A 4QLEA 3HBBA 1IA3A 1DIUA 3EEKA 3QLYA 1DHIA 3NZ9X 4IXGX 2G6VA 3DRCA 1RX2A 1AI9A 3TQ9A 1PD9A 1DDSA 1M7AA 1SEJA 5HF0X 4X5GA 3NXOA 3OAFA 4I1NA 4DDRA 2QK8A 3NU0A 5HVBA 4KY4A 1JOLA 1DR3A 4NX6A 3FQVA 3DATA 1RX8A 1U72A 3DL5A 4PSTA 4Q0DA 3FRBX 5HI6A 3I3RA 1JUVA 1QZFA 3K47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EEM A;  2HM9 A;  1VJ3 A;  2DHF A;  3JSU A;  3F91 A;  4G95 A;  4KJL A;  1DYI A;  1DR4 A;  4KAK A;  1RB2 A;  4H96 A;  4X5H A;  2W3A A;  3FQO A;  1RD7 A;  2ZZA A;  3FQZ A;  5HT5 A;  1PD8 A;  1RC4 A;  3KJR A;  3JWF A;  1RX7 A;  2ANQ A;  1D1G A;  3N0H A;  1LUD A;  3DAU A;  5DXV A;  3ZPG A;  4X5F A;  3FYW X;  3SR5 X;  3CD2 A;  2W3V A;  2HQP A;  3F0B X;  3NXY A;  4OSG A;  2BLB A;  4Q6A A;  1RX6 A;  1PDB A;  3IRO A;  4P68 A;  4ELH A;  1RE7 A;  3E0B A;  1VDR A;  3FRF X;  4HOF A;  2C2S A;  4X5J A;  5DFR A;  4EIZ A;  3HJ3 A;  3CL9 A;  2W9H A;  1HFR A;  4XT6 A;  1RA3 A;  5E8Q A;  3NRR A;  5HUI A;  4FGH A;  1HFP A;  3L3R A;  3IRN A;  4P3Q A;  2FZH A;  3QLW A;  3M09 A;  1U70 A;  4QHV A;  3DGA A;  3R33 A;  3IRM A;  3K2H A;  5HQZ A;  1LY3 A;  7DFR A;  4M6L A;  2LF1 A;  3TQB A;  3JWM A;  3FY8 X;  1DRB A;  3FRA X;  4XRB A;  1DR2 A;  3GHV A;  1DR7 A;  1DIS A;  4HOE A;  3IX9 A;  4XE6 X;  4KJK A;  1RX3 A;  5ECC A;  2FZJ A;  2ITH A;  4XT7 A;  5HT4 A;  2CIG A;  4FGG A;  3EEL A;  1RF7 A;  4G3M A;  1DRE A;  3FQ0 A;  4EIG A;  1CZ3 A;  1KMS A;  3GHW A;  4DPH A;  4HOG A;  5FDA A;  3S7A A;  2W9G A;  3QLR A;  4KY8 A;  5HQY A;  4ECK A;  1CD2 A;  2P4G A;  4KYA A;  4IXF X;  3DL6 A;  5JG0 X;  1HFQ A;  4QI9 A;  3RO9 A;  4RGC A;  4KD7 A;  4XT5 A;  3JWK A;  3Q1H A;  3QG2 A;  4G8Z X;  3DFR A;  3JW3 A;  3GI2 A;  1AO8 A;  4KNE A;  4XEC X;  4I13 A;  3SRS X;  3FL9 A;  1DG5 A;  1DLS A;  2D0K A;  3DG8 A;  3S3V A;  4H95 A;  2W3M A;  3TQA A;  4ELG A;  4OR7 A;  4QLF A;  4XT8 A;  3INV A;  3TQ8 A;  3JVX A;  1S3U A;  4DPD A;  3UM5 A;  3KJS A;  3NXT A;  3JWC A;  3F0S X;  5HF2 X;  2W3B A;  5EAJ A;  5U26 A;  4HA9 A;  5HPB A;  1MVT A;  5HSR A;  2INQ A;  3IA4 A;  3ROA A;  2CD2 A;  4KLX A;  3NXX A;  3QYO A;  3NZ6 X;  2W9T A;  1RA1 A;  1BOZ A;  3IA5 A;  1OHJ A;  1LY4 A;  1DYJ A;  3D80 A;  5JA3 A;  2C2T A;  2BLA A;  4KBN A;  1RX4 A;  4TU5 X;  3FS6 A;  4QLG A;  1DDR A;  3JW5 A;  1DYH A;  3UM6 A;  1RA8 A;  3K74 A;  2AZN A;  1S3V A;  4KM2 A;  3JTW A;  4X5I A;  3QL3 A;  3D84 X;  3NXV A;  3GYF A;  1TDR A;  1DR5 A;  2BL9 A;  4LAG X;  4HA7 A;  4LAE X;  4PSS A;  2D5N A;  3SGY A;  1DHJ A;  2XW7 A;  3EEJ A;  2W3W A;  3SAI A;  5U27 A;  3FQF A;  4DFR A;  2ANO A;  2W9S A;  4P66 A;  1KLK A;  4GH8 A;  1U71 A;  4Q0E A;  2B3Z A;  1DG8 A;  1J3K A;  3OCH A;  3SRU X;  1DRA A;  4EIL A;  3CSE A;  3KY8 A;  4KM0 A;  1RA9 A;  1DF7 A;  4M7V A;  3K45 A;  3SA2 A;  1MVS A;  3KGY A;  2O7P A;  4CD2 A;  4PDJ A;  3EX8 A;  5CC9 A;  3RG9 A;  3GHC A;  3F0V X;  5ECX A;  3ZPC A;  3QYL A;  1RG7 A;  3SRQ X;  1DRF A;  1DR6 A;  1DYR A;  1JOM A;  1S3Y A;  1DR1 A;  3NZD A;  3UM8 A;  1ZDR A;  3VCO A;  2DRC A;  4KFJ A;  2OIP A;  1M78 A;  2JYB A;  3NTZ A;  3F8Y A;  3SRR X;  4M6J A;  3SA1 A;  1J3J A;  2FZI A;  3NXR A;  3SH2 A;  4FHB A;  1RX1 A;  3KFY A;  3QGT A;  3F8Z A;  6DFR A;  4P3R A;  1RX5 A;  3QLZ A;  4KJJ A;  1DG7 A;  1M79 A;  5HSU A;  1DLR A;  4IXE D;  3QLX A;  1DRH A;  4M7U A;  3SQY X;  3F0X X;  4M2X A;  1RH3 A;  1DAJ A;  3FL8 A;  3FRE X;  3NZA X;  4NX7 A;  4ELE A;  1KMV A;  3QFX A;  4KEB A;  4M6K A;  3S9U A;  4ELB A;  4KL9 A;  2KGK A;  8DFR A;  3EIG A;  1RB3 A;  3LG4 A;  3SRW X;  4QJZ D;  2OBC A;  1IA2 A;  4H97 A;  3M08 A;  3I8A X;  4EJ1 A;  1S3W A;  4QJC A;  4PTH A;  2H2Q A;  1OHK A;  3FRD X;  3F0U X;  4LAH X;  2BLC A;  3FQC A;  4XT4 A;  4Q67 A;  1J3I A;  1BZF A;  3F0Q X;  3TD8 A;  4PSY A;  3QLS A;  1YHO A;  2L28 A;  3NZB X;  4LEK X;  1E26 A;  1IA4 A;  1IA1 A;  2GD9 A;  1DHF A;  1RX9 A;  3CLB A;  5CCC A;  3FY9 X;  4ELF A;  1AOE A;  3QL0 A;  3NZC X;  4DP3 A;  1RA2 A;  4PTJ A;  2HXV A;  3FYV X;  5HVE A;  4H98 A;  4QLE A;  3HBB A;  1IA3 A;  1DIU A;  3EEK A;  3QLY A;  1DHI A;  3NZ9 X;  4IXG X;  2G6V A;  3DRC A;  1RX2 A;  1AI9 A;  3TQ9 A;  1PD9 A;  1DDS A;  1M7A A;  1SEJ A;  5HF0 X;  4X5G A;  3NXO A;  3OAF A;  4I1N A;  4DDR A;  2QK8 A;  3NU0 A;  5HVB A;  4KY4 A;  1JOL A;  1DR3 A;  4NX6 A;  3FQV A;  3DAT A;  1RX8 A;  1U72 A;  3DL5 A;  4PST A;  4Q0D A;  3FRB X;  5HI6 A;  3I3R A;  1JUV A;  1QZF A;  3K47 A; 
#chains in the Genus database with same CATH topology
 3EEM A;  2HM9 A;  1VJ3 A;  2DHF A;  3JSU A;  3F91 A;  4G95 A;  4KJL A;  1DYI A;  1DR4 A;  4KAK A;  1RB2 A;  4H96 A;  4X5H A;  2W3A A;  3FQO A;  1RD7 A;  2ZZA A;  3FQZ A;  5HT5 A;  1PD8 A;  1RC4 A;  3KJR A;  3JWF A;  1RX7 A;  2ANQ A;  1D1G A;  3N0H A;  1LUD A;  3DAU A;  5DXV A;  3ZPG A;  4X5F A;  3FYW X;  3SR5 X;  3CD2 A;  2W3V A;  2HQP A;  3F0B X;  3NXY A;  4OSG A;  2BLB A;  4Q6A A;  1RX6 A;  1PDB A;  3IRO A;  4P68 A;  4ELH A;  1RE7 A;  3E0B A;  1VDR A;  3FRF X;  4HOF A;  2C2S A;  4X5J A;  5DFR A;  4EIZ A;  3HJ3 A;  3CL9 A;  2W9H A;  1HFR A;  4XT6 A;  1RA3 A;  5E8Q A;  3NRR A;  5HUI A;  4FGH A;  1HFP A;  3L3R A;  3IRN A;  4P3Q A;  2FZH A;  3QLW A;  3M09 A;  1U70 A;  4QHV A;  3DGA A;  3R33 A;  3IRM A;  3K2H A;  5HQZ A;  1LY3 A;  7DFR A;  4M6L A;  2LF1 A;  3TQB A;  3JWM A;  3FY8 X;  1DRB A;  3FRA X;  4XRB A;  1DR2 A;  3GHV A;  1DR7 A;  1DIS A;  4HOE A;  3IX9 A;  4XE6 X;  4KJK A;  1RX3 A;  5ECC A;  2FZJ A;  2ITH A;  4XT7 A;  5HT4 A;  2CIG A;  4FGG A;  3EEL A;  1RF7 A;  4G3M A;  1DRE A;  3FQ0 A;  4EIG A;  1CZ3 A;  1KMS A;  3GHW A;  4DPH A;  4HOG A;  5FDA A;  3S7A A;  2W9G A;  3QLR A;  4KY8 A;  5HQY A;  4ECK A;  1CD2 A;  2P4G A;  4KYA A;  4IXF X;  3DL6 A;  5JG0 X;  1HFQ A;  4QI9 A;  3RO9 A;  4RGC A;  4KD7 A;  4XT5 A;  3JWK A;  3Q1H A;  3QG2 A;  4G8Z X;  3DFR A;  3JW3 A;  3GI2 A;  1AO8 A;  4KNE A;  4XEC X;  4I13 A;  3SRS X;  3FL9 A;  1DG5 A;  1DLS A;  2D0K A;  3DG8 A;  3S3V A;  4H95 A;  2W3M A;  3TQA A;  4ELG A;  4OR7 A;  4QLF A;  4XT8 A;  3INV A;  3TQ8 A;  3JVX A;  1S3U A;  4DPD A;  3UM5 A;  3KJS A;  3NXT A;  3JWC A;  3F0S X;  5HF2 X;  2W3B A;  5EAJ A;  5U26 A;  4HA9 A;  5HPB A;  1MVT A;  5HSR A;  2INQ A;  3IA4 A;  3ROA A;  2CD2 A;  4KLX A;  3NXX A;  3QYO A;  3NZ6 X;  2W9T A;  1RA1 A;  1BOZ A;  3IA5 A;  1OHJ A;  1LY4 A;  1DYJ A;  3D80 A;  5JA3 A;  2C2T A;  2BLA A;  4KBN A;  1RX4 A;  4TU5 X;  3FS6 A;  4QLG A;  1DDR A;  3JW5 A;  1DYH A;  3UM6 A;  1RA8 A;  3K74 A;  2AZN A;  1S3V A;  4KM2 A;  3JTW A;  4X5I A;  3QL3 A;  3D84 X;  3NXV A;  3GYF A;  1TDR A;  1DR5 A;  2BL9 A;  4LAG X;  4HA7 A;  4LAE X;  4PSS A;  2D5N A;  3SGY A;  1DHJ A;  2XW7 A;  3EEJ A;  2W3W A;  3SAI A;  5U27 A;  3FQF A;  4DFR A;  2ANO A;  2W9S A;  4P66 A;  1KLK A;  4GH8 A;  1U71 A;  4Q0E A;  2B3Z A;  1DG8 A;  1J3K A;  3OCH A;  3SRU X;  1DRA A;  4EIL A;  3CSE A;  3KY8 A;  4KM0 A;  1RA9 A;  1DF7 A;  4M7V A;  3K45 A;  3SA2 A;  1MVS A;  3KGY A;  2O7P A;  4CD2 A;  4PDJ A;  3EX8 A;  5CC9 A;  3RG9 A;  3GHC A;  3F0V X;  5ECX A;  3ZPC A;  3QYL A;  1RG7 A;  3SRQ X;  1DRF A;  1DR6 A;  1DYR A;  1JOM A;  1S3Y A;  1DR1 A;  3NZD A;  3UM8 A;  1ZDR A;  3VCO A;  2DRC A;  4KFJ A;  2OIP A;  1M78 A;  2JYB A;  3NTZ A;  3F8Y A;  3SRR X;  4M6J A;  3SA1 A;  1J3J A;  2FZI A;  3NXR A;  3SH2 A;  4FHB A;  1RX1 A;  3KFY A;  3QGT A;  3F8Z A;  6DFR A;  4P3R A;  1RX5 A;  3QLZ A;  4KJJ A;  1DG7 A;  1M79 A;  5HSU A;  1DLR A;  4IXE D;  3QLX A;  1DRH A;  4M7U A;  3SQY X;  3F0X X;  4M2X A;  1RH3 A;  1DAJ A;  3FL8 A;  3FRE X;  3NZA X;  4NX7 A;  4ELE A;  1KMV A;  3QFX A;  4KEB A;  4M6K A;  3S9U A;  4ELB A;  4KL9 A;  2KGK A;  8DFR A;  3EIG A;  1RB3 A;  3LG4 A;  3SRW X;  4QJZ D;  2OBC A;  1IA2 A;  4H97 A;  3M08 A;  3I8A X;  4EJ1 A;  1S3W A;  4QJC A;  4PTH A;  2H2Q A;  1OHK A;  3FRD X;  3F0U X;  4LAH X;  2BLC A;  3FQC A;  4XT4 A;  4Q67 A;  1J3I A;  1BZF A;  3F0Q X;  3TD8 A;  4PSY A;  3QLS A;  1YHO A;  2L28 A;  3NZB X;  4LEK X;  1E26 A;  1IA4 A;  1IA1 A;  2GD9 A;  1DHF A;  1RX9 A;  3CLB A;  5CCC A;  3FY9 X;  4ELF A;  1AOE A;  3QL0 A;  3NZC X;  4DP3 A;  1RA2 A;  4PTJ A;  2HXV A;  3FYV X;  5HVE A;  4H98 A;  4QLE A;  3HBB A;  1IA3 A;  1DIU A;  3EEK A;  3QLY A;  1DHI A;  3NZ9 X;  4IXG X;  2G6V A;  3DRC A;  1RX2 A;  1AI9 A;  3TQ9 A;  1PD9 A;  1DDS A;  1M7A A;  1SEJ A;  5HF0 X;  4X5G A;  3NXO A;  3OAF A;  4I1N A;  4DDR A;  2QK8 A;  3NU0 A;  5HVB A;  4KY4 A;  1JOL A;  1DR3 A;  4NX6 A;  3FQV A;  3DAT A;  1RX8 A;  1U72 A;  3DL5 A;  4PST A;  4Q0D A;  3FRB X;  5HI6 A;  3I3R A;  1JUV A;  1QZF A;  3K47 A; 
#chains in the Genus database with same CATH homology
 3EEM A;  2HM9 A;  1VJ3 A;  2DHF A;  3JSU A;  3F91 A;  4G95 A;  4KJL A;  1DYI A;  1DR4 A;  4KAK A;  1RB2 A;  4H96 A;  4X5H A;  2W3A A;  3FQO A;  1RD7 A;  2ZZA A;  3FQZ A;  5HT5 A;  1PD8 A;  1RC4 A;  3KJR A;  3JWF A;  1RX7 A;  2ANQ A;  1D1G A;  3N0H A;  1LUD A;  3DAU A;  5DXV A;  3ZPG A;  4X5F A;  3FYW X;  3SR5 X;  3CD2 A;  2W3V A;  2HQP A;  3F0B X;  3NXY A;  4OSG A;  2BLB A;  4Q6A A;  1RX6 A;  1PDB A;  3IRO A;  4P68 A;  4ELH A;  1RE7 A;  3E0B A;  1VDR A;  3FRF X;  4HOF A;  2C2S A;  4X5J A;  5DFR A;  4EIZ A;  3HJ3 A;  3CL9 A;  2W9H A;  1HFR A;  4XT6 A;  1RA3 A;  5E8Q A;  3NRR A;  5HUI A;  4FGH A;  1HFP A;  3L3R A;  3IRN A;  4P3Q A;  2FZH A;  3QLW A;  3M09 A;  1U70 A;  4QHV A;  3DGA A;  3R33 A;  3IRM A;  3K2H A;  5HQZ A;  1LY3 A;  7DFR A;  4M6L A;  2LF1 A;  3TQB A;  3JWM A;  3FY8 X;  1DRB A;  3FRA X;  4XRB A;  1DR2 A;  3GHV A;  1DR7 A;  1DIS A;  4HOE A;  3IX9 A;  4XE6 X;  4KJK A;  1RX3 A;  5ECC A;  2FZJ A;  2ITH A;  4XT7 A;  5HT4 A;  2CIG A;  4FGG A;  3EEL A;  1RF7 A;  4G3M A;  1DRE A;  3FQ0 A;  4EIG A;  1CZ3 A;  1KMS A;  3GHW A;  4DPH A;  4HOG A;  5FDA A;  3S7A A;  2W9G A;  3QLR A;  4KY8 A;  5HQY A;  4ECK A;  1CD2 A;  2P4G A;  4KYA A;  4IXF X;  3DL6 A;  5JG0 X;  1HFQ A;  4QI9 A;  3RO9 A;  4RGC A;  4KD7 A;  4XT5 A;  3JWK A;  3Q1H A;  3QG2 A;  4G8Z X;  3DFR A;  3JW3 A;  3GI2 A;  1AO8 A;  4KNE A;  4XEC X;  4I13 A;  3SRS X;  3FL9 A;  1DG5 A;  1DLS A;  2D0K A;  3DG8 A;  3S3V A;  4H95 A;  2W3M A;  3TQA A;  4ELG A;  4OR7 A;  4QLF A;  4XT8 A;  3INV A;  3TQ8 A;  3JVX A;  1S3U A;  4DPD A;  3UM5 A;  3KJS A;  3NXT A;  3JWC A;  3F0S X;  5HF2 X;  2W3B A;  5EAJ A;  5U26 A;  4HA9 A;  5HPB A;  1MVT A;  5HSR A;  2INQ A;  3IA4 A;  3ROA A;  2CD2 A;  4KLX A;  3NXX A;  3QYO A;  3NZ6 X;  2W9T A;  1RA1 A;  1BOZ A;  3IA5 A;  1OHJ A;  1LY4 A;  1DYJ A;  3D80 A;  5JA3 A;  2C2T A;  2BLA A;  4KBN A;  1RX4 A;  4TU5 X;  3FS6 A;  4QLG A;  1DDR A;  3JW5 A;  1DYH A;  3UM6 A;  1RA8 A;  3K74 A;  2AZN A;  1S3V A;  4KM2 A;  3JTW A;  4X5I A;  3QL3 A;  3D84 X;  3NXV A;  3GYF A;  1TDR A;  1DR5 A;  2BL9 A;  4LAG X;  4HA7 A;  4LAE X;  4PSS A;  2D5N A;  3SGY A;  1DHJ A;  2XW7 A;  3EEJ A;  2W3W A;  3SAI A;  5U27 A;  3FQF A;  4DFR A;  2ANO A;  2W9S A;  4P66 A;  1KLK A;  4GH8 A;  1U71 A;  4Q0E A;  2B3Z A;  1DG8 A;  1J3K A;  3OCH A;  3SRU X;  1DRA A;  4EIL A;  3CSE A;  3KY8 A;  4KM0 A;  1RA9 A;  1DF7 A;  4M7V A;  3K45 A;  3SA2 A;  1MVS A;  3KGY A;  2O7P A;  4CD2 A;  4PDJ A;  3EX8 A;  5CC9 A;  3RG9 A;  3GHC A;  3F0V X;  5ECX A;  3ZPC A;  3QYL A;  1RG7 A;  3SRQ X;  1DRF A;  1DR6 A;  1DYR A;  1JOM A;  1S3Y A;  1DR1 A;  3NZD A;  3UM8 A;  1ZDR A;  3VCO A;  2DRC A;  4KFJ A;  2OIP A;  1M78 A;  2JYB A;  3NTZ A;  3F8Y A;  3SRR X;  4M6J A;  3SA1 A;  1J3J A;  2FZI A;  3NXR A;  3SH2 A;  4FHB A;  1RX1 A;  3KFY A;  3QGT A;  3F8Z A;  6DFR A;  4P3R A;  1RX5 A;  3QLZ A;  4KJJ A;  1DG7 A;  1M79 A;  5HSU A;  1DLR A;  4IXE D;  3QLX A;  1DRH A;  4M7U A;  3SQY X;  3F0X X;  4M2X A;  1RH3 A;  1DAJ A;  3FL8 A;  3FRE X;  3NZA X;  4NX7 A;  4ELE A;  1KMV A;  3QFX A;  4KEB A;  4M6K A;  3S9U A;  4ELB A;  4KL9 A;  2KGK A;  8DFR A;  3EIG A;  1RB3 A;  3LG4 A;  3SRW X;  4QJZ D;  2OBC A;  1IA2 A;  4H97 A;  3M08 A;  3I8A X;  4EJ1 A;  1S3W A;  4QJC A;  4PTH A;  2H2Q A;  1OHK A;  3FRD X;  3F0U X;  4LAH X;  2BLC A;  3FQC A;  4XT4 A;  4Q67 A;  1J3I A;  1BZF A;  3F0Q X;  3TD8 A;  4PSY A;  3QLS A;  1YHO A;  2L28 A;  3NZB X;  4LEK X;  1E26 A;  1IA4 A;  1IA1 A;  2GD9 A;  1DHF A;  1RX9 A;  3CLB A;  5CCC A;  3FY9 X;  4ELF A;  1AOE A;  3QL0 A;  3NZC X;  4DP3 A;  1RA2 A;  4PTJ A;  2HXV A;  3FYV X;  5HVE A;  4H98 A;  4QLE A;  3HBB A;  1IA3 A;  1DIU A;  3EEK A;  3QLY A;  1DHI A;  3NZ9 X;  4IXG X;  2G6V A;  3DRC A;  1RX2 A;  1AI9 A;  3TQ9 A;  1PD9 A;  1DDS A;  1M7A A;  1SEJ A;  5HF0 X;  4X5G A;  3NXO A;  3OAF A;  4I1N A;  4DDR A;  2QK8 A;  3NU0 A;  5HVB A;  4KY4 A;  1JOL A;  1DR3 A;  4NX6 A;  3FQV A;  3DAT A;  1RX8 A;  1U72 A;  3DL5 A;  4PST A;  4Q0D A;  3FRB X;  5HI6 A;  3I3R A;  1JUV A;  1QZF A;  3K47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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