3I8AX

Staphylococcus aureus h30n, f98y dihydrofolate reductase complexed with nadph and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (ucp120b)
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKNVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Staphylococcus aureus
molecule keywords Dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3i8aX00
1DR7A 2D5NA 4HOEA 1RX9A 3JTWA 3QLSA 3F0XX 2FZJA 1D1GA 1RX8A 3TQBA 3FREX 1DR5A 3N0HA 2W3BA 3JWKA 3QL3A 1DR1A 3M08A 4PSTA 1AI9A 1RD7A 3Q1HA 1DR3A 5EAJA 3I8AX 4KLXA 1J3IA 3K45A 3NZCX 4KEBA 3SRWX 5HVEA 1E26A 4LAGX 1RX5A 4XECX 5CCCA 3DATA 3EX8A 4IXFX 3FYVX 2INQA 3NZ9X 3RO9A 3NZBX 4GH8A 2W9TA 4QI9A 3QGTA 3FRDX 1RX1A 3EEKA 3ZPCA 4M6LA 4TU5X 3F91A 3ZPGA 2BLBA 4HOGA 4FGGA 3JWCA 1DRBA 3K74A 3UM5A 4M6KA 4DFRA 3FQOA 4P66A 4PSSA 3SRRX 3EIGA 2HQPA 4Q6AA 3GHCA 5HSUA 3CLBA 1YHOA 3CD2A 3NZ6X 4M2XA 1ZDRA 3GHVA 4IXED 4KD7A 1DHFA 2ITHA 3FS6A 3DG8A 3IA4A 3SA1A 3NXVA 2C2TA 4ECKA 4P3RA 1DG8A 1DG7A 4FGHA 4QLFA 1CD2A 1DRHA 1S3YA 2ZZAA 5FDAA 3GYFA 3INVA 1RB2A 1RG7A 4RGCA 4H95A 2W9HA 1BZFA 2W3WA 4XT5A 1HFPA 4P3QA 3NXYA 3SA2A 3E0BA 3IA5A 5HI6A 3FQVA 5HT4A 3L3RA 1DHIA 4H96A 4ELBA 1DHJA 1RE7A 4X5IA 2DRCA 3F8YA 4KJKA 3QYLA 3NTZA 1KLKA 5ECCA 5HF0X 5U26A 1RA9A 3SRSX 1AOEA 4M6JA 1IA4A 3JW3A 2DHFA 2HXVA 5DFRA 4KYAA 2KGKA 3FQFA 3FRBX 1DAJA 1OHKA 5JA3A 3DFRA 3QLWA 2CD2A 3FL8A 1S3VA 4P68A 3SH2A 2HM9A 2W3MA 2OBCA 5JG0X 2W9GA 3SRQX 2BL9A 2P4GA 3NXRA 3KJSA 1RA3A 4ELHA 2C2SA 5E8QA 3IROA 1IA2A 7DFRA 3SGYA 1J3KA 3DRCA 4FHBA 2W3VA 6DFRA 4NX6A 3EELA 4Q0EA 3QLXA 3KGYA 3OAFA 4X5HA 3TQAA 2O7PA 1LUDA 4DDRA 3TQ9A 1RF7A 1DR2A 5DXVA 3S9UA 3DL5A 1JOLA 1RB3A 3QL0A 3S7AA 3FRFX 1RA2A 1JOMA 5HVBA 4G95A 3NZAX 2AZNA 3IX9A 4IXGX 1DYRA 5HQYA 3S3VA 3K47A 1DREA 4I1NA 3EEJA 4HOFA 1M78A 4X5FA 3DL6A 1DYJA 3JW5A 4H98A 3FYWX 4M7VA 1RX3A 3NXXA 3GHWA 3NZDA 3FRAX 1S3WA 4PTHA 3HJ3A 4OR7A 2W9SA 4KY4A 4X5GA 2XW7A 5HT5A 3IRMA 3KJRA 3OCHA 4KAKA 4QLGA 3JWFA 1PD8A 4DPDA 1RH3A 1CZ3A 1SEJA 3JVXA 5HSRA 1DYHA 3NXOA 4ELFA 1PDBA 3UM6A 2BLAA 3FL9A 2GD9A 4QLEA 3QLRA 3NRRA 1U71A 3SRUX 5U27A 3KFYA 3CL9A 1VDRA 4DP3A 1DLSA 4EJ1A 3SR5X 2D0KA 1DG5A 4KY8A 3QLZA 4KM2A 3UM8A 2B3ZA 3KY8A 2LF1A 1J3JA 2OIPA 1LY3A 3F0VX 3VCOA 1DR6A 4CD2A 1S3UA 4LAEX 3M09A 1DRFA 4XT4A 4ELEA 1DDRA 1LY4A 4OSGA 1M7AA 1IA3A 4PDJA 3F0UX 4X5JA 3F0QX 3IRNA 1RX2A 2G6VA 3FQ0A 4HA9A 4NX7A 3JWMA 3FQCA 4G8ZX 4QHVA 1DRAA 1KMVA 3SQYX 3CSEA 3ROAA 4LEKX 3RG9A 1JUVA 3FQZA 4QJZD 1PD9A 4LAHX 2ANOA 1HFQA 4XT6A 1RA1A 1M79A 3I3RA 4HA7A 4ELGA 2W3AA 3D84X 3R33A 3TQ8A 2H2QA 4EILA 1RX6A 4KJLA 2FZIA 5CC9A 1AO8A 2QK8A 4KJJA 4KFJA 5HQZA 3LG4A 1DIUA 1KMSA 3HBBA 1DLRA 4XT8A 3SAIA 1QZFA 2L28A 3F8ZA 1RX7A 3DAUA 1RA8A 4H97A 3FY8X 4KNEA 1DYIA 3EEMA 5HPBA 3QFXA 4M7UA 1DF7A 3K2HA 3NXTA 3JSUA 4KM0A 5HUIA 1RC4A 3FY9X 4KBNA 2ANQA 3GI2A 3DGAA 4XE6X 3QYOA 4KL9A 1U72A 4I13A 1VJ3A 5HF2X 1U70A 5ECXA 4DPHA 4EIGA 1TDRA 1DDSA 4XT7A 4G3MA 4Q67A 3NU0A 3TD8A 3F0SX 1MVTA 1HFRA 1BOZA 3F0BX 1IA1A 1OHJA 2CIGA 2FZHA 4PTJA 1DR4A 3QLYA 2JYBA 1DISA 4QJCA 8DFRA 3QG2A 1MVSA 1RX4A 4XRBA 4Q0DA 4PSYA 2BLCA 3D80A 4EIZA
chains in the Genus database with same CATH superfamily
1DR7A 2D5NA 4HOEA 1RX9A 3JTWA 3QLSA 3F0XX 2FZJA 1D1GA 1RX8A 3TQBA 3FREX 1DR5A 3N0HA 2W3BA 3JWKA 3QL3A 1DR1A 3M08A 4PSTA 1AI9A 1RD7A 3Q1HA 1DR3A 5EAJA 3I8AX 4KLXA 1J3IA 3K45A 3NZCX 4KEBA 3SRWX 5HVEA 1E26A 4LAGX 1RX5A 4XECX 5CCCA 3DATA 3EX8A 4IXFX 3FYVX 2INQA 3NZ9X 3RO9A 3NZBX 4GH8A 2W9TA 4QI9A 3QGTA 3FRDX 1RX1A 3EEKA 3ZPCA 4M6LA 4TU5X 3F91A 3ZPGA 2BLBA 4HOGA 4FGGA 3JWCA 1DRBA 3K74A 3UM5A 4M6KA 4DFRA 3FQOA 4P66A 4PSSA 3SRRX 3EIGA 2HQPA 4Q6AA 3GHCA 5HSUA 3CLBA 1YHOA 3CD2A 3NZ6X 4M2XA 1ZDRA 3GHVA 4IXED 4KD7A 1DHFA 2ITHA 3FS6A 3DG8A 3IA4A 3SA1A 3NXVA 2C2TA 4ECKA 4P3RA 1DG8A 1DG7A 4FGHA 4QLFA 1CD2A 1DRHA 1S3YA 2ZZAA 5FDAA 3GYFA 3INVA 1RB2A 1RG7A 4RGCA 4H95A 2W9HA 1BZFA 2W3WA 4XT5A 1HFPA 4P3QA 3NXYA 3SA2A 3E0BA 3IA5A 5HI6A 3FQVA 5HT4A 3L3RA 1DHIA 4H96A 4ELBA 1DHJA 1RE7A 4X5IA 2DRCA 3F8YA 4KJKA 3QYLA 3NTZA 1KLKA 5ECCA 5HF0X 5U26A 1RA9A 3SRSX 1AOEA 4M6JA 1IA4A 3JW3A 2DHFA 2HXVA 5DFRA 4KYAA 2KGKA 3FQFA 3FRBX 1DAJA 1OHKA 5JA3A 3DFRA 3QLWA 2CD2A 3FL8A 1S3VA 4P68A 3SH2A 2HM9A 2W3MA 2OBCA 5JG0X 2W9GA 3SRQX 2BL9A 2P4GA 3NXRA 3KJSA 1RA3A 4ELHA 2C2SA 5E8QA 3IROA 1IA2A 7DFRA 3SGYA 1J3KA 3DRCA 4FHBA 2W3VA 6DFRA 4NX6A 3EELA 4Q0EA 3QLXA 3KGYA 3OAFA 4X5HA 3TQAA 2O7PA 1LUDA 4DDRA 3TQ9A 1RF7A 1DR2A 5DXVA 3S9UA 3DL5A 1JOLA 1RB3A 3QL0A 3S7AA 3FRFX 1RA2A 1JOMA 5HVBA 4G95A 3NZAX 2AZNA 3IX9A 4IXGX 1DYRA 5HQYA 3S3VA 3K47A 1DREA 4I1NA 3EEJA 4HOFA 1M78A 4X5FA 3DL6A 1DYJA 3JW5A 4H98A 3FYWX 4M7VA 1RX3A 3NXXA 3GHWA 3NZDA 3FRAX 1S3WA 4PTHA 3HJ3A 4OR7A 2W9SA 4KY4A 4X5GA 2XW7A 5HT5A 3IRMA 3KJRA 3OCHA 4KAKA 4QLGA 3JWFA 1PD8A 4DPDA 1RH3A 1CZ3A 1SEJA 3JVXA 5HSRA 1DYHA 3NXOA 4ELFA 1PDBA 3UM6A 2BLAA 3FL9A 2GD9A 4QLEA 3QLRA 3NRRA 1U71A 3SRUX 5U27A 3KFYA 3CL9A 1VDRA 4DP3A 1DLSA 4EJ1A 3SR5X 2D0KA 1DG5A 4KY8A 3QLZA 4KM2A 3UM8A 2B3ZA 3KY8A 2LF1A 1J3JA 2OIPA 1LY3A 3F0VX 3VCOA 1DR6A 4CD2A 1S3UA 4LAEX 3M09A 1DRFA 4XT4A 4ELEA 1DDRA 1LY4A 4OSGA 1M7AA 1IA3A 4PDJA 3F0UX 4X5JA 3F0QX 3IRNA 1RX2A 2G6VA 3FQ0A 4HA9A 4NX7A 3JWMA 3FQCA 4G8ZX 4QHVA 1DRAA 1KMVA 3SQYX 3CSEA 3ROAA 4LEKX 3RG9A 1JUVA 3FQZA 4QJZD 1PD9A 4LAHX 2ANOA 1HFQA 4XT6A 1RA1A 1M79A 3I3RA 4HA7A 4ELGA 2W3AA 3D84X 3R33A 3TQ8A 2H2QA 4EILA 1RX6A 4KJLA 2FZIA 5CC9A 1AO8A 2QK8A 4KJJA 4KFJA 5HQZA 3LG4A 1DIUA 1KMSA 3HBBA 1DLRA 4XT8A 3SAIA 1QZFA 2L28A 3F8ZA 1RX7A 3DAUA 1RA8A 4H97A 3FY8X 4KNEA 1DYIA 3EEMA 5HPBA 3QFXA 4M7UA 1DF7A 3K2HA 3NXTA 3JSUA 4KM0A 5HUIA 1RC4A 3FY9X 4KBNA 2ANQA 3GI2A 3DGAA 4XE6X 3QYOA 4KL9A 1U72A 4I13A 1VJ3A 5HF2X 1U70A 5ECXA 4DPHA 4EIGA 1TDRA 1DDSA 4XT7A 4G3MA 4Q67A 3NU0A 3TD8A 3F0SX 1MVTA 1HFRA 1BOZA 3F0BX 1IA1A 1OHJA 2CIGA 2FZHA 4PTJA 1DR4A 3QLYA 2JYBA 1DISA 4QJCA 8DFRA 3QG2A 1MVSA 1RX4A 4XRBA 4Q0DA 4PSYA 2BLCA 3D80A 4EIZA
chains in the Genus database with same CATH topology
1DR7A 2D5NA 4HOEA 1RX9A 3JTWA 3QLSA 3F0XX 2FZJA 1D1GA 1RX8A 3TQBA 3FREX 1DR5A 3N0HA 2W3BA 3JWKA 3QL3A 1DR1A 3M08A 4PSTA 1AI9A 1RD7A 3Q1HA 1DR3A 5EAJA 3I8AX 4KLXA 1J3IA 3K45A 3NZCX 4KEBA 3SRWX 5HVEA 1E26A 4LAGX 1RX5A 4XECX 5CCCA 3DATA 3EX8A 4IXFX 3FYVX 2INQA 3NZ9X 3RO9A 3NZBX 4GH8A 2W9TA 4QI9A 3QGTA 3FRDX 1RX1A 3EEKA 3ZPCA 4M6LA 4TU5X 3F91A 3ZPGA 2BLBA 4HOGA 4FGGA 3JWCA 1DRBA 3K74A 3UM5A 4M6KA 4DFRA 3FQOA 4P66A 4PSSA 3SRRX 3EIGA 2HQPA 4Q6AA 3GHCA 5HSUA 3CLBA 1YHOA 3CD2A 3NZ6X 4M2XA 1ZDRA 3GHVA 4IXED 4KD7A 1DHFA 2ITHA 3FS6A 3DG8A 3IA4A 3SA1A 3NXVA 2C2TA 4ECKA 4P3RA 1DG8A 1DG7A 4FGHA 4QLFA 1CD2A 1DRHA 1S3YA 2ZZAA 5FDAA 3GYFA 3INVA 1RB2A 1RG7A 4RGCA 4H95A 2W9HA 1BZFA 2W3WA 4XT5A 1HFPA 4P3QA 3NXYA 3SA2A 3E0BA 3IA5A 5HI6A 3FQVA 5HT4A 3L3RA 1DHIA 4H96A 4ELBA 1DHJA 1RE7A 4X5IA 2DRCA 3F8YA 4KJKA 3QYLA 3NTZA 1KLKA 5ECCA 5HF0X 5U26A 1RA9A 3SRSX 1AOEA 4M6JA 1IA4A 3JW3A 2DHFA 2HXVA 5DFRA 4KYAA 2KGKA 3FQFA 3FRBX 1DAJA 1OHKA 5JA3A 3DFRA 3QLWA 2CD2A 3FL8A 1S3VA 4P68A 3SH2A 2HM9A 2W3MA 2OBCA 5JG0X 2W9GA 3SRQX 2BL9A 2P4GA 3NXRA 3KJSA 1RA3A 4ELHA 2C2SA 5E8QA 3IROA 1IA2A 7DFRA 3SGYA 1J3KA 3DRCA 4FHBA 2W3VA 6DFRA 4NX6A 3EELA 4Q0EA 3QLXA 3KGYA 3OAFA 4X5HA 3TQAA 2O7PA 1LUDA 4DDRA 3TQ9A 1RF7A 1DR2A 5DXVA 3S9UA 3DL5A 1JOLA 1RB3A 3QL0A 3S7AA 3FRFX 1RA2A 1JOMA 5HVBA 4G95A 3NZAX 2AZNA 3IX9A 4IXGX 1DYRA 5HQYA 3S3VA 3K47A 1DREA 4I1NA 3EEJA 4HOFA 1M78A 4X5FA 3DL6A 1DYJA 3JW5A 4H98A 3FYWX 4M7VA 1RX3A 3NXXA 3GHWA 3NZDA 3FRAX 1S3WA 4PTHA 3HJ3A 4OR7A 2W9SA 4KY4A 4X5GA 2XW7A 5HT5A 3IRMA 3KJRA 3OCHA 4KAKA 4QLGA 3JWFA 1PD8A 4DPDA 1RH3A 1CZ3A 1SEJA 3JVXA 5HSRA 1DYHA 3NXOA 4ELFA 1PDBA 3UM6A 2BLAA 3FL9A 2GD9A 4QLEA 3QLRA 3NRRA 1U71A 3SRUX 5U27A 3KFYA 3CL9A 1VDRA 4DP3A 1DLSA 4EJ1A 3SR5X 2D0KA 1DG5A 4KY8A 3QLZA 4KM2A 3UM8A 2B3ZA 3KY8A 2LF1A 1J3JA 2OIPA 1LY3A 3F0VX 3VCOA 1DR6A 4CD2A 1S3UA 4LAEX 3M09A 1DRFA 4XT4A 4ELEA 1DDRA 1LY4A 4OSGA 1M7AA 1IA3A 4PDJA 3F0UX 4X5JA 3F0QX 3IRNA 1RX2A 2G6VA 3FQ0A 4HA9A 4NX7A 3JWMA 3FQCA 4G8ZX 4QHVA 1DRAA 1KMVA 3SQYX 3CSEA 3ROAA 4LEKX 3RG9A 1JUVA 3FQZA 4QJZD 1PD9A 4LAHX 2ANOA 1HFQA 4XT6A 1RA1A 1M79A 3I3RA 4HA7A 4ELGA 2W3AA 3D84X 3R33A 3TQ8A 2H2QA 4EILA 1RX6A 4KJLA 2FZIA 5CC9A 1AO8A 2QK8A 4KJJA 4KFJA 5HQZA 3LG4A 1DIUA 1KMSA 3HBBA 1DLRA 4XT8A 3SAIA 1QZFA 2L28A 3F8ZA 1RX7A 3DAUA 1RA8A 4H97A 3FY8X 4KNEA 1DYIA 3EEMA 5HPBA 3QFXA 4M7UA 1DF7A 3K2HA 3NXTA 3JSUA 4KM0A 5HUIA 1RC4A 3FY9X 4KBNA 2ANQA 3GI2A 3DGAA 4XE6X 3QYOA 4KL9A 1U72A 4I13A 1VJ3A 5HF2X 1U70A 5ECXA 4DPHA 4EIGA 1TDRA 1DDSA 4XT7A 4G3MA 4Q67A 3NU0A 3TD8A 3F0SX 1MVTA 1HFRA 1BOZA 3F0BX 1IA1A 1OHJA 2CIGA 2FZHA 4PTJA 1DR4A 3QLYA 2JYBA 1DISA 4QJCA 8DFRA 3QG2A 1MVSA 1RX4A 4XRBA 4Q0DA 4PSYA 2BLCA 3D80A 4EIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DR7 A;  2D5N A;  4HOE A;  1RX9 A;  3JTW A;  3QLS A;  3F0X X;  2FZJ A;  1D1G A;  1RX8 A;  3TQB A;  3FRE X;  1DR5 A;  3N0H A;  2W3B A;  3JWK A;  3QL3 A;  1DR1 A;  3M08 A;  4PST A;  1AI9 A;  1RD7 A;  3Q1H A;  1DR3 A;  5EAJ A;  3I8A X;  4KLX A;  1J3I A;  3K45 A;  3NZC X;  4KEB A;  3SRW X;  5HVE A;  1E26 A;  4LAG X;  1RX5 A;  4XEC X;  5CCC A;  3DAT A;  3EX8 A;  4IXF X;  3FYV X;  2INQ A;  3NZ9 X;  3RO9 A;  3NZB X;  4GH8 A;  2W9T A;  4QI9 A;  3QGT A;  3FRD X;  1RX1 A;  3EEK A;  3ZPC A;  4M6L A;  4TU5 X;  3F91 A;  3ZPG A;  2BLB A;  4HOG A;  4FGG A;  3JWC A;  1DRB A;  3K74 A;  3UM5 A;  4M6K A;  4DFR A;  3FQO A;  4P66 A;  4PSS A;  3SRR X;  3EIG A;  2HQP A;  4Q6A A;  3GHC A;  5HSU A;  3CLB A;  1YHO A;  3CD2 A;  3NZ6 X;  4M2X A;  1ZDR A;  3GHV A;  4IXE D;  4KD7 A;  1DHF A;  2ITH A;  3FS6 A;  3DG8 A;  3IA4 A;  3SA1 A;  3NXV A;  2C2T A;  4ECK A;  4P3R A;  1DG8 A;  1DG7 A;  4FGH A;  4QLF A;  1CD2 A;  1DRH A;  1S3Y A;  2ZZA A;  5FDA A;  3GYF A;  3INV A;  1RB2 A;  1RG7 A;  4RGC A;  4H95 A;  2W9H A;  1BZF A;  2W3W A;  4XT5 A;  1HFP A;  4P3Q A;  3NXY A;  3SA2 A;  3E0B A;  3IA5 A;  5HI6 A;  3FQV A;  5HT4 A;  3L3R A;  1DHI A;  4H96 A;  4ELB A;  1DHJ A;  1RE7 A;  4X5I A;  2DRC A;  3F8Y A;  4KJK A;  3QYL A;  3NTZ A;  1KLK A;  5ECC A;  5HF0 X;  5U26 A;  1RA9 A;  3SRS X;  1AOE A;  4M6J A;  1IA4 A;  3JW3 A;  2DHF A;  2HXV A;  5DFR A;  4KYA A;  2KGK A;  3FQF A;  3FRB X;  1DAJ A;  1OHK A;  5JA3 A;  3DFR A;  3QLW A;  2CD2 A;  3FL8 A;  1S3V A;  4P68 A;  3SH2 A;  2HM9 A;  2W3M A;  2OBC A;  5JG0 X;  2W9G A;  3SRQ X;  2BL9 A;  2P4G A;  3NXR A;  3KJS A;  1RA3 A;  4ELH A;  2C2S A;  5E8Q A;  3IRO A;  1IA2 A;  7DFR A;  3SGY A;  1J3K A;  3DRC A;  4FHB A;  2W3V A;  6DFR A;  4NX6 A;  3EEL A;  4Q0E A;  3QLX A;  3KGY A;  3OAF A;  4X5H A;  3TQA A;  2O7P A;  1LUD A;  4DDR A;  3TQ9 A;  1RF7 A;  1DR2 A;  5DXV A;  3S9U A;  3DL5 A;  1JOL A;  1RB3 A;  3QL0 A;  3S7A A;  3FRF X;  1RA2 A;  1JOM A;  5HVB A;  4G95 A;  3NZA X;  2AZN A;  3IX9 A;  4IXG X;  1DYR A;  5HQY A;  3S3V A;  3K47 A;  1DRE A;  4I1N A;  3EEJ A;  4HOF A;  1M78 A;  4X5F A;  3DL6 A;  1DYJ A;  3JW5 A;  4H98 A;  3FYW X;  4M7V A;  1RX3 A;  3NXX A;  3GHW A;  3NZD A;  3FRA X;  1S3W A;  4PTH A;  3HJ3 A;  4OR7 A;  2W9S A;  4KY4 A;  4X5G A;  2XW7 A;  5HT5 A;  3IRM A;  3KJR A;  3OCH A;  4KAK A;  4QLG A;  3JWF A;  1PD8 A;  4DPD A;  1RH3 A;  1CZ3 A;  1SEJ A;  3JVX A;  5HSR A;  1DYH A;  3NXO A;  4ELF A;  1PDB A;  3UM6 A;  2BLA A;  3FL9 A;  2GD9 A;  4QLE A;  3QLR A;  3NRR A;  1U71 A;  3SRU X;  5U27 A;  3KFY A;  3CL9 A;  1VDR A;  4DP3 A;  1DLS A;  4EJ1 A;  3SR5 X;  2D0K A;  1DG5 A;  4KY8 A;  3QLZ A;  4KM2 A;  3UM8 A;  2B3Z A;  3KY8 A;  2LF1 A;  1J3J A;  2OIP A;  1LY3 A;  3F0V X;  3VCO A;  1DR6 A;  4CD2 A;  1S3U A;  4LAE X;  3M09 A;  1DRF A;  4XT4 A;  4ELE A;  1DDR A;  1LY4 A;  4OSG A;  1M7A A;  1IA3 A;  4PDJ A;  3F0U X;  4X5J A;  3F0Q X;  3IRN A;  1RX2 A;  2G6V A;  3FQ0 A;  4HA9 A;  4NX7 A;  3JWM A;  3FQC A;  4G8Z X;  4QHV A;  1DRA A;  1KMV A;  3SQY X;  3CSE A;  3ROA A;  4LEK X;  3RG9 A;  1JUV A;  3FQZ A;  4QJZ D;  1PD9 A;  4LAH X;  2ANO A;  1HFQ A;  4XT6 A;  1RA1 A;  1M79 A;  3I3R A;  4HA7 A;  4ELG A;  2W3A A;  3D84 X;  3R33 A;  3TQ8 A;  2H2Q A;  4EIL A;  1RX6 A;  4KJL A;  2FZI A;  5CC9 A;  1AO8 A;  2QK8 A;  4KJJ A;  4KFJ A;  5HQZ A;  3LG4 A;  1DIU A;  1KMS A;  3HBB A;  1DLR A;  4XT8 A;  3SAI A;  1QZF A;  2L28 A;  3F8Z A;  1RX7 A;  3DAU A;  1RA8 A;  4H97 A;  3FY8 X;  4KNE A;  1DYI A;  3EEM A;  5HPB A;  3QFX A;  4M7U A;  1DF7 A;  3K2H A;  3NXT A;  3JSU A;  4KM0 A;  5HUI A;  1RC4 A;  3FY9 X;  4KBN A;  2ANQ A;  3GI2 A;  3DGA A;  4XE6 X;  3QYO A;  4KL9 A;  1U72 A;  4I13 A;  1VJ3 A;  5HF2 X;  1U70 A;  5ECX A;  4DPH A;  4EIG A;  1TDR A;  1DDS A;  4XT7 A;  4G3M A;  4Q67 A;  3NU0 A;  3TD8 A;  3F0S X;  1MVT A;  1HFR A;  1BOZ A;  3F0B X;  1IA1 A;  1OHJ A;  2CIG A;  2FZH A;  4PTJ A;  1DR4 A;  3QLY A;  2JYB A;  1DIS A;  4QJC A;  8DFR A;  3QG2 A;  1MVS A;  1RX4 A;  4XRB A;  4Q0D A;  4PSY A;  2BLC A;  3D80 A;  4EIZ A; 
#chains in the Genus database with same CATH topology
 1DR7 A;  2D5N A;  4HOE A;  1RX9 A;  3JTW A;  3QLS A;  3F0X X;  2FZJ A;  1D1G A;  1RX8 A;  3TQB A;  3FRE X;  1DR5 A;  3N0H A;  2W3B A;  3JWK A;  3QL3 A;  1DR1 A;  3M08 A;  4PST A;  1AI9 A;  1RD7 A;  3Q1H A;  1DR3 A;  5EAJ A;  3I8A X;  4KLX A;  1J3I A;  3K45 A;  3NZC X;  4KEB A;  3SRW X;  5HVE A;  1E26 A;  4LAG X;  1RX5 A;  4XEC X;  5CCC A;  3DAT A;  3EX8 A;  4IXF X;  3FYV X;  2INQ A;  3NZ9 X;  3RO9 A;  3NZB X;  4GH8 A;  2W9T A;  4QI9 A;  3QGT A;  3FRD X;  1RX1 A;  3EEK A;  3ZPC A;  4M6L A;  4TU5 X;  3F91 A;  3ZPG A;  2BLB A;  4HOG A;  4FGG A;  3JWC A;  1DRB A;  3K74 A;  3UM5 A;  4M6K A;  4DFR A;  3FQO A;  4P66 A;  4PSS A;  3SRR X;  3EIG A;  2HQP A;  4Q6A A;  3GHC A;  5HSU A;  3CLB A;  1YHO A;  3CD2 A;  3NZ6 X;  4M2X A;  1ZDR A;  3GHV A;  4IXE D;  4KD7 A;  1DHF A;  2ITH A;  3FS6 A;  3DG8 A;  3IA4 A;  3SA1 A;  3NXV A;  2C2T A;  4ECK A;  4P3R A;  1DG8 A;  1DG7 A;  4FGH A;  4QLF A;  1CD2 A;  1DRH A;  1S3Y A;  2ZZA A;  5FDA A;  3GYF A;  3INV A;  1RB2 A;  1RG7 A;  4RGC A;  4H95 A;  2W9H A;  1BZF A;  2W3W A;  4XT5 A;  1HFP A;  4P3Q A;  3NXY A;  3SA2 A;  3E0B A;  3IA5 A;  5HI6 A;  3FQV A;  5HT4 A;  3L3R A;  1DHI A;  4H96 A;  4ELB A;  1DHJ A;  1RE7 A;  4X5I A;  2DRC A;  3F8Y A;  4KJK A;  3QYL A;  3NTZ A;  1KLK A;  5ECC A;  5HF0 X;  5U26 A;  1RA9 A;  3SRS X;  1AOE A;  4M6J A;  1IA4 A;  3JW3 A;  2DHF A;  2HXV A;  5DFR A;  4KYA A;  2KGK A;  3FQF A;  3FRB X;  1DAJ A;  1OHK A;  5JA3 A;  3DFR A;  3QLW A;  2CD2 A;  3FL8 A;  1S3V A;  4P68 A;  3SH2 A;  2HM9 A;  2W3M A;  2OBC A;  5JG0 X;  2W9G A;  3SRQ X;  2BL9 A;  2P4G A;  3NXR A;  3KJS A;  1RA3 A;  4ELH A;  2C2S A;  5E8Q A;  3IRO A;  1IA2 A;  7DFR A;  3SGY A;  1J3K A;  3DRC A;  4FHB A;  2W3V A;  6DFR A;  4NX6 A;  3EEL A;  4Q0E A;  3QLX A;  3KGY A;  3OAF A;  4X5H A;  3TQA A;  2O7P A;  1LUD A;  4DDR A;  3TQ9 A;  1RF7 A;  1DR2 A;  5DXV A;  3S9U A;  3DL5 A;  1JOL A;  1RB3 A;  3QL0 A;  3S7A A;  3FRF X;  1RA2 A;  1JOM A;  5HVB A;  4G95 A;  3NZA X;  2AZN A;  3IX9 A;  4IXG X;  1DYR A;  5HQY A;  3S3V A;  3K47 A;  1DRE A;  4I1N A;  3EEJ A;  4HOF A;  1M78 A;  4X5F A;  3DL6 A;  1DYJ A;  3JW5 A;  4H98 A;  3FYW X;  4M7V A;  1RX3 A;  3NXX A;  3GHW A;  3NZD A;  3FRA X;  1S3W A;  4PTH A;  3HJ3 A;  4OR7 A;  2W9S A;  4KY4 A;  4X5G A;  2XW7 A;  5HT5 A;  3IRM A;  3KJR A;  3OCH A;  4KAK A;  4QLG A;  3JWF A;  1PD8 A;  4DPD A;  1RH3 A;  1CZ3 A;  1SEJ A;  3JVX A;  5HSR A;  1DYH A;  3NXO A;  4ELF A;  1PDB A;  3UM6 A;  2BLA A;  3FL9 A;  2GD9 A;  4QLE A;  3QLR A;  3NRR A;  1U71 A;  3SRU X;  5U27 A;  3KFY A;  3CL9 A;  1VDR A;  4DP3 A;  1DLS A;  4EJ1 A;  3SR5 X;  2D0K A;  1DG5 A;  4KY8 A;  3QLZ A;  4KM2 A;  3UM8 A;  2B3Z A;  3KY8 A;  2LF1 A;  1J3J A;  2OIP A;  1LY3 A;  3F0V X;  3VCO A;  1DR6 A;  4CD2 A;  1S3U A;  4LAE X;  3M09 A;  1DRF A;  4XT4 A;  4ELE A;  1DDR A;  1LY4 A;  4OSG A;  1M7A A;  1IA3 A;  4PDJ A;  3F0U X;  4X5J A;  3F0Q X;  3IRN A;  1RX2 A;  2G6V A;  3FQ0 A;  4HA9 A;  4NX7 A;  3JWM A;  3FQC A;  4G8Z X;  4QHV A;  1DRA A;  1KMV A;  3SQY X;  3CSE A;  3ROA A;  4LEK X;  3RG9 A;  1JUV A;  3FQZ A;  4QJZ D;  1PD9 A;  4LAH X;  2ANO A;  1HFQ A;  4XT6 A;  1RA1 A;  1M79 A;  3I3R A;  4HA7 A;  4ELG A;  2W3A A;  3D84 X;  3R33 A;  3TQ8 A;  2H2Q A;  4EIL A;  1RX6 A;  4KJL A;  2FZI A;  5CC9 A;  1AO8 A;  2QK8 A;  4KJJ A;  4KFJ A;  5HQZ A;  3LG4 A;  1DIU A;  1KMS A;  3HBB A;  1DLR A;  4XT8 A;  3SAI A;  1QZF A;  2L28 A;  3F8Z A;  1RX7 A;  3DAU A;  1RA8 A;  4H97 A;  3FY8 X;  4KNE A;  1DYI A;  3EEM A;  5HPB A;  3QFX A;  4M7U A;  1DF7 A;  3K2H A;  3NXT A;  3JSU A;  4KM0 A;  5HUI A;  1RC4 A;  3FY9 X;  4KBN A;  2ANQ A;  3GI2 A;  3DGA A;  4XE6 X;  3QYO A;  4KL9 A;  1U72 A;  4I13 A;  1VJ3 A;  5HF2 X;  1U70 A;  5ECX A;  4DPH A;  4EIG A;  1TDR A;  1DDS A;  4XT7 A;  4G3M A;  4Q67 A;  3NU0 A;  3TD8 A;  3F0S X;  1MVT A;  1HFR A;  1BOZ A;  3F0B X;  1IA1 A;  1OHJ A;  2CIG A;  2FZH A;  4PTJ A;  1DR4 A;  3QLY A;  2JYB A;  1DIS A;  4QJC A;  8DFR A;  3QG2 A;  1MVS A;  1RX4 A;  4XRB A;  4Q0D A;  4PSY A;  2BLC A;  3D80 A;  4EIZ A; 
#chains in the Genus database with same CATH homology
 1DR7 A;  2D5N A;  4HOE A;  1RX9 A;  3JTW A;  3QLS A;  3F0X X;  2FZJ A;  1D1G A;  1RX8 A;  3TQB A;  3FRE X;  1DR5 A;  3N0H A;  2W3B A;  3JWK A;  3QL3 A;  1DR1 A;  3M08 A;  4PST A;  1AI9 A;  1RD7 A;  3Q1H A;  1DR3 A;  5EAJ A;  3I8A X;  4KLX A;  1J3I A;  3K45 A;  3NZC X;  4KEB A;  3SRW X;  5HVE A;  1E26 A;  4LAG X;  1RX5 A;  4XEC X;  5CCC A;  3DAT A;  3EX8 A;  4IXF X;  3FYV X;  2INQ A;  3NZ9 X;  3RO9 A;  3NZB X;  4GH8 A;  2W9T A;  4QI9 A;  3QGT A;  3FRD X;  1RX1 A;  3EEK A;  3ZPC A;  4M6L A;  4TU5 X;  3F91 A;  3ZPG A;  2BLB A;  4HOG A;  4FGG A;  3JWC A;  1DRB A;  3K74 A;  3UM5 A;  4M6K A;  4DFR A;  3FQO A;  4P66 A;  4PSS A;  3SRR X;  3EIG A;  2HQP A;  4Q6A A;  3GHC A;  5HSU A;  3CLB A;  1YHO A;  3CD2 A;  3NZ6 X;  4M2X A;  1ZDR A;  3GHV A;  4IXE D;  4KD7 A;  1DHF A;  2ITH A;  3FS6 A;  3DG8 A;  3IA4 A;  3SA1 A;  3NXV A;  2C2T A;  4ECK A;  4P3R A;  1DG8 A;  1DG7 A;  4FGH A;  4QLF A;  1CD2 A;  1DRH A;  1S3Y A;  2ZZA A;  5FDA A;  3GYF A;  3INV A;  1RB2 A;  1RG7 A;  4RGC A;  4H95 A;  2W9H A;  1BZF A;  2W3W A;  4XT5 A;  1HFP A;  4P3Q A;  3NXY A;  3SA2 A;  3E0B A;  3IA5 A;  5HI6 A;  3FQV A;  5HT4 A;  3L3R A;  1DHI A;  4H96 A;  4ELB A;  1DHJ A;  1RE7 A;  4X5I A;  2DRC A;  3F8Y A;  4KJK A;  3QYL A;  3NTZ A;  1KLK A;  5ECC A;  5HF0 X;  5U26 A;  1RA9 A;  3SRS X;  1AOE A;  4M6J A;  1IA4 A;  3JW3 A;  2DHF A;  2HXV A;  5DFR A;  4KYA A;  2KGK A;  3FQF A;  3FRB X;  1DAJ A;  1OHK A;  5JA3 A;  3DFR A;  3QLW A;  2CD2 A;  3FL8 A;  1S3V A;  4P68 A;  3SH2 A;  2HM9 A;  2W3M A;  2OBC A;  5JG0 X;  2W9G A;  3SRQ X;  2BL9 A;  2P4G A;  3NXR A;  3KJS A;  1RA3 A;  4ELH A;  2C2S A;  5E8Q A;  3IRO A;  1IA2 A;  7DFR A;  3SGY A;  1J3K A;  3DRC A;  4FHB A;  2W3V A;  6DFR A;  4NX6 A;  3EEL A;  4Q0E A;  3QLX A;  3KGY A;  3OAF A;  4X5H A;  3TQA A;  2O7P A;  1LUD A;  4DDR A;  3TQ9 A;  1RF7 A;  1DR2 A;  5DXV A;  3S9U A;  3DL5 A;  1JOL A;  1RB3 A;  3QL0 A;  3S7A A;  3FRF X;  1RA2 A;  1JOM A;  5HVB A;  4G95 A;  3NZA X;  2AZN A;  3IX9 A;  4IXG X;  1DYR A;  5HQY A;  3S3V A;  3K47 A;  1DRE A;  4I1N A;  3EEJ A;  4HOF A;  1M78 A;  4X5F A;  3DL6 A;  1DYJ A;  3JW5 A;  4H98 A;  3FYW X;  4M7V A;  1RX3 A;  3NXX A;  3GHW A;  3NZD A;  3FRA X;  1S3W A;  4PTH A;  3HJ3 A;  4OR7 A;  2W9S A;  4KY4 A;  4X5G A;  2XW7 A;  5HT5 A;  3IRM A;  3KJR A;  3OCH A;  4KAK A;  4QLG A;  3JWF A;  1PD8 A;  4DPD A;  1RH3 A;  1CZ3 A;  1SEJ A;  3JVX A;  5HSR A;  1DYH A;  3NXO A;  4ELF A;  1PDB A;  3UM6 A;  2BLA A;  3FL9 A;  2GD9 A;  4QLE A;  3QLR A;  3NRR A;  1U71 A;  3SRU X;  5U27 A;  3KFY A;  3CL9 A;  1VDR A;  4DP3 A;  1DLS A;  4EJ1 A;  3SR5 X;  2D0K A;  1DG5 A;  4KY8 A;  3QLZ A;  4KM2 A;  3UM8 A;  2B3Z A;  3KY8 A;  2LF1 A;  1J3J A;  2OIP A;  1LY3 A;  3F0V X;  3VCO A;  1DR6 A;  4CD2 A;  1S3U A;  4LAE X;  3M09 A;  1DRF A;  4XT4 A;  4ELE A;  1DDR A;  1LY4 A;  4OSG A;  1M7A A;  1IA3 A;  4PDJ A;  3F0U X;  4X5J A;  3F0Q X;  3IRN A;  1RX2 A;  2G6V A;  3FQ0 A;  4HA9 A;  4NX7 A;  3JWM A;  3FQC A;  4G8Z X;  4QHV A;  1DRA A;  1KMV A;  3SQY X;  3CSE A;  3ROA A;  4LEK X;  3RG9 A;  1JUV A;  3FQZ A;  4QJZ D;  1PD9 A;  4LAH X;  2ANO A;  1HFQ A;  4XT6 A;  1RA1 A;  1M79 A;  3I3R A;  4HA7 A;  4ELG A;  2W3A A;  3D84 X;  3R33 A;  3TQ8 A;  2H2Q A;  4EIL A;  1RX6 A;  4KJL A;  2FZI A;  5CC9 A;  1AO8 A;  2QK8 A;  4KJJ A;  4KFJ A;  5HQZ A;  3LG4 A;  1DIU A;  1KMS A;  3HBB A;  1DLR A;  4XT8 A;  3SAI A;  1QZF A;  2L28 A;  3F8Z A;  1RX7 A;  3DAU A;  1RA8 A;  4H97 A;  3FY8 X;  4KNE A;  1DYI A;  3EEM A;  5HPB A;  3QFX A;  4M7U A;  1DF7 A;  3K2H A;  3NXT A;  3JSU A;  4KM0 A;  5HUI A;  1RC4 A;  3FY9 X;  4KBN A;  2ANQ A;  3GI2 A;  3DGA A;  4XE6 X;  3QYO A;  4KL9 A;  1U72 A;  4I13 A;  1VJ3 A;  5HF2 X;  1U70 A;  5ECX A;  4DPH A;  4EIG A;  1TDR A;  1DDS A;  4XT7 A;  4G3M A;  4Q67 A;  3NU0 A;  3TD8 A;  3F0S X;  1MVT A;  1HFR A;  1BOZ A;  3F0B X;  1IA1 A;  1OHJ A;  2CIG A;  2FZH A;  4PTJ A;  1DR4 A;  3QLY A;  2JYB A;  1DIS A;  4QJC A;  8DFR A;  3QG2 A;  1MVS A;  1RX4 A;  4XRB A;  4Q0D A;  4PSY A;  2BLC A;  3D80 A;  4EIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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