3IX9A

Crystal structure of streptococcus pneumoniae dihydrofolate reductase - sp9 mutant
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
166
structure length
166
Chain Sequence
TKKIVAIWAQDEEGVIGKDNRLPWYLPAELQHFKETTLNHAILMGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFHDVQSVLDWYSAQEKNLYIVGGKQIFQAFEPYLDEVIVTHIHARVEGDTYFPAEFDLSLFETVSSKFYTKDEKNPYDFTIQYRKRKE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptococcus pneumoniae
molecule keywords Dihydrofolate reductase
total genus 44
structure length 166
sequence length 166
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-09-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3ix9A00
3FRFX 2OIPA 1DYRA 3KGYA 1S3WA 2G6VA 3I8AX 4KJLA 4PSTA 3R33A 1M79A 4QJZD 4X5JA 4LAEX 3NZ9X 4H97A 1PD9A 1RX4A 2O7PA 2LF1A 3QLYA 4KM2A 3SRUX 2D0KA 4XE6X 2HXVA 7DFRA 4KJKA 2BLAA 1DREA 2W9TA 1IA3A 4HA7A 4ELHA 4G3MA 2ANOA 3DRCA 4M6KA 1OHJA 4XT8A 4QI9A 1RA2A 4ELFA 3ZPGA 4PSSA 1VDRA 1E26A 1CD2A 3FQCA 3NXVA 3NXYA 3DL5A 3DATA 1HFRA 1AO8A 2W9GA 3FS6A 5CCCA 2XW7A 3NXOA 3IX9A 4ELEA 1PDBA 3JW5A 1RB3A 1HFQA 3QLZA 1RX8A 4I1NA 1DISA 1AI9A 1DDSA 1DG7A 3GHVA 2DRCA 3F8YA 4KBNA 3IA5A 1DYJA 4KFJA 1DR3A 1RF7A 1MVSA 1DR5A 1S3VA 1S3YA 2HM9A 2L28A 5ECXA 1KMVA 3TQ8A 4P3QA 3UM8A 2FZJA 2D5NA 4HOGA 4XECX 3GHWA 1BZFA 3DFRA 2B3ZA 1M7AA 1CZ3A 3JVXA 1DAJA 3D84X 4X5FA 4QHVA 4PSYA 4M7UA 2W3VA 4EJ1A 3F8ZA 4Q0DA 4EIGA 2C2SA 4X5IA 2ZZAA 4IXGX 1RC4A 3F91A 1PD8A 4KD7A 3EX8A 5HF2X 4KAKA 4P68A 2DHFA 3GI2A 3CLBA 5HT5A 4Q67A 4OR7A 5DXVA 3QLRA 1RA3A 4LAGX 3K2HA 3JWMA 4RGCA 3D80A 1RX2A 4OSGA 3SQYX 1QZFA 1RX9A 3SR5X 3SRQX 3SRWX 2W3AA 4I13A 2C2TA 4XT4A 2ITHA 5HQYA 4H95A 5HUIA 4HOFA 1J3IA 3EEJA 4LAHX 4XT7A 4KEBA 4QLEA 2INQA 2W9SA 3LG4A 1HFPA 1RX1A 3RG9A 3OCHA 4KNEA 5ECCA 1DG5A 1TDRA 3QGTA 1JOMA 5HF0X 5HQZA 3RO9A 3S3VA 3EEKA 3ZPCA 4NX7A 3FRBX 3NU0A 1U70A 4XRBA 3JWFA 3NTZA 1LUDA 4LEKX 1BOZA 2HQPA 5JA3A 4NX6A 3S7AA 2CD2A 1ZDRA 1DRFA 1SEJA 3SAIA 1DIUA 3FY8X 1OHKA 2W3MA 4PTJA 3SA1A 3I3RA 3FQFA 3NRRA 4KL9A 1AOEA 5HSRA 3F0SX 3JW3A 3FRDX 3E0BA 4PDJA 4ECKA 1U72A 1DHFA 2GD9A 3K45A 4EILA 3SGYA 3CL9A 4PTHA 4XT6A 3QFXA 3JSUA 3TD8A 2H2QA 3KFYA 3QLWA 2ANQA 1U71A 3INVA 4H98A 1DRAA 4TU5X 5HI6A 3QG2A 3QLXA 4M7VA 3M09A 1RX6A 3CD2A 4DPHA 3FQOA 2BLCA 3FQVA 3NZDA 1DG8A 1DF7A 3F0VX 4HA9A 1RB2A 1S3UA 4G95A 1RE7A 2CIGA 5HVEA 4M6JA 4DDRA 2W3BA 5HT4A 1JOLA 3K47A 1RH3A 1LY3A 3JTWA 3EIGA 3FRAX 1RX5A 3UM5A 3F0QX 3NZCX 3NZAX 3IA4A 5U27A 4HOEA 1RA8A 3DAUA 4QLGA 3NZ6X 4ELBA 1DDRA 2FZHA 1DRHA 3FY9X 3QL3A 4H96A 1IA1A 3CSEA 5EAJA 4FGGA 3NXRA 3HBBA 4P66A 4ELGA 4DFRA 3QL0A 1YHOA 3SRRX 3QYOA 3GHCA 3K74A 3EEMA 4DP3A 2BLBA 3TQ9A 1RG7A 3NZBX 1DHIA 1DR7A 4M2XA 4KYAA 5HVBA 5HPBA 4QLFA 3F0XX 3F0BX 4KLXA 3JWKA 4DPDA 3KJSA 1DYIA 3DL6A 1KLKA 2OBCA 3QLSA 3TQAA 4FHBA 4GH8A 5U26A 3VCOA 1MVTA 1DR2A 3QYLA 4X5GA 3FQZA 3S9UA 3DG8A 4KY8A 5DFRA 3FYVX 2QK8A 1M78A 3FL8A 3IRNA 3ROAA 1LY4A 2JYBA 2P4GA 3Q1HA 1RD7A 3M08A 4KM0A 1DLRA 3HJ3A 3TQBA 1DLSA 1IA2A 2AZNA 1DHJA 4CD2A 4KJJA 3FL9A 2BL9A 4EIZA 1DRBA 3NXXA 1J3JA 5E8QA 1IA4A 3L3RA 3IRMA 3SH2A 3KY8A 3F0UX 1RX3A 1DR1A 3SRSX 4P3RA 3UM6A 1DR6A 1D1GA 4G8ZX 4Q6AA 5JG0X 1VJ3A 1KMSA 4KY4A 4Q0EA 1RA1A 2W3WA 5CC9A 1RA9A 3IROA 4IXFX 4M6LA 4X5HA 4XT5A 1DR4A 3JWCA 1RX7A 3FQ0A 2W9HA 6DFRA 1J3KA 3SA2A 3EELA 3GYFA 2KGKA 2FZIA 3N0HA 3OAFA 5HSUA 1JUVA 3FYWX 4QJCA 8DFRA 3DGAA 4IXED 3FREX 5FDAA 3NXTA 4FGHA 1DYHA 3KJRA
chains in the Genus database with same CATH superfamily
3FRFX 2OIPA 1DYRA 3KGYA 1S3WA 2G6VA 3I8AX 4KJLA 4PSTA 3R33A 1M79A 4QJZD 4X5JA 4LAEX 3NZ9X 4H97A 1PD9A 1RX4A 2O7PA 2LF1A 3QLYA 4KM2A 3SRUX 2D0KA 4XE6X 2HXVA 7DFRA 4KJKA 2BLAA 1DREA 2W9TA 1IA3A 4HA7A 4ELHA 4G3MA 2ANOA 3DRCA 4M6KA 1OHJA 4XT8A 4QI9A 1RA2A 4ELFA 3ZPGA 4PSSA 1VDRA 1E26A 1CD2A 3FQCA 3NXVA 3NXYA 3DL5A 3DATA 1HFRA 1AO8A 2W9GA 3FS6A 5CCCA 2XW7A 3NXOA 3IX9A 4ELEA 1PDBA 3JW5A 1RB3A 1HFQA 3QLZA 1RX8A 4I1NA 1DISA 1AI9A 1DDSA 1DG7A 3GHVA 2DRCA 3F8YA 4KBNA 3IA5A 1DYJA 4KFJA 1DR3A 1RF7A 1MVSA 1DR5A 1S3VA 1S3YA 2HM9A 2L28A 5ECXA 1KMVA 3TQ8A 4P3QA 3UM8A 2FZJA 2D5NA 4HOGA 4XECX 3GHWA 1BZFA 3DFRA 2B3ZA 1M7AA 1CZ3A 3JVXA 1DAJA 3D84X 4X5FA 4QHVA 4PSYA 4M7UA 2W3VA 4EJ1A 3F8ZA 4Q0DA 4EIGA 2C2SA 4X5IA 2ZZAA 4IXGX 1RC4A 3F91A 1PD8A 4KD7A 3EX8A 5HF2X 4KAKA 4P68A 2DHFA 3GI2A 3CLBA 5HT5A 4Q67A 4OR7A 5DXVA 3QLRA 1RA3A 4LAGX 3K2HA 3JWMA 4RGCA 3D80A 1RX2A 4OSGA 3SQYX 1QZFA 1RX9A 3SR5X 3SRQX 3SRWX 2W3AA 4I13A 2C2TA 4XT4A 2ITHA 5HQYA 4H95A 5HUIA 4HOFA 1J3IA 3EEJA 4LAHX 4XT7A 4KEBA 4QLEA 2INQA 2W9SA 3LG4A 1HFPA 1RX1A 3RG9A 3OCHA 4KNEA 5ECCA 1DG5A 1TDRA 3QGTA 1JOMA 5HF0X 5HQZA 3RO9A 3S3VA 3EEKA 3ZPCA 4NX7A 3FRBX 3NU0A 1U70A 4XRBA 3JWFA 3NTZA 1LUDA 4LEKX 1BOZA 2HQPA 5JA3A 4NX6A 3S7AA 2CD2A 1ZDRA 1DRFA 1SEJA 3SAIA 1DIUA 3FY8X 1OHKA 2W3MA 4PTJA 3SA1A 3I3RA 3FQFA 3NRRA 4KL9A 1AOEA 5HSRA 3F0SX 3JW3A 3FRDX 3E0BA 4PDJA 4ECKA 1U72A 1DHFA 2GD9A 3K45A 4EILA 3SGYA 3CL9A 4PTHA 4XT6A 3QFXA 3JSUA 3TD8A 2H2QA 3KFYA 3QLWA 2ANQA 1U71A 3INVA 4H98A 1DRAA 4TU5X 5HI6A 3QG2A 3QLXA 4M7VA 3M09A 1RX6A 3CD2A 4DPHA 3FQOA 2BLCA 3FQVA 3NZDA 1DG8A 1DF7A 3F0VX 4HA9A 1RB2A 1S3UA 4G95A 1RE7A 2CIGA 5HVEA 4M6JA 4DDRA 2W3BA 5HT4A 1JOLA 3K47A 1RH3A 1LY3A 3JTWA 3EIGA 3FRAX 1RX5A 3UM5A 3F0QX 3NZCX 3NZAX 3IA4A 5U27A 4HOEA 1RA8A 3DAUA 4QLGA 3NZ6X 4ELBA 1DDRA 2FZHA 1DRHA 3FY9X 3QL3A 4H96A 1IA1A 3CSEA 5EAJA 4FGGA 3NXRA 3HBBA 4P66A 4ELGA 4DFRA 3QL0A 1YHOA 3SRRX 3QYOA 3GHCA 3K74A 3EEMA 4DP3A 2BLBA 3TQ9A 1RG7A 3NZBX 1DHIA 1DR7A 4M2XA 4KYAA 5HVBA 5HPBA 4QLFA 3F0XX 3F0BX 4KLXA 3JWKA 4DPDA 3KJSA 1DYIA 3DL6A 1KLKA 2OBCA 3QLSA 3TQAA 4FHBA 4GH8A 5U26A 3VCOA 1MVTA 1DR2A 3QYLA 4X5GA 3FQZA 3S9UA 3DG8A 4KY8A 5DFRA 3FYVX 2QK8A 1M78A 3FL8A 3IRNA 3ROAA 1LY4A 2JYBA 2P4GA 3Q1HA 1RD7A 3M08A 4KM0A 1DLRA 3HJ3A 3TQBA 1DLSA 1IA2A 2AZNA 1DHJA 4CD2A 4KJJA 3FL9A 2BL9A 4EIZA 1DRBA 3NXXA 1J3JA 5E8QA 1IA4A 3L3RA 3IRMA 3SH2A 3KY8A 3F0UX 1RX3A 1DR1A 3SRSX 4P3RA 3UM6A 1DR6A 1D1GA 4G8ZX 4Q6AA 5JG0X 1VJ3A 1KMSA 4KY4A 4Q0EA 1RA1A 2W3WA 5CC9A 1RA9A 3IROA 4IXFX 4M6LA 4X5HA 4XT5A 1DR4A 3JWCA 1RX7A 3FQ0A 2W9HA 6DFRA 1J3KA 3SA2A 3EELA 3GYFA 2KGKA 2FZIA 3N0HA 3OAFA 5HSUA 1JUVA 3FYWX 4QJCA 8DFRA 3DGAA 4IXED 3FREX 5FDAA 3NXTA 4FGHA 1DYHA 3KJRA
chains in the Genus database with same CATH topology
3FRFX 2OIPA 1DYRA 3KGYA 1S3WA 2G6VA 3I8AX 4KJLA 4PSTA 3R33A 1M79A 4QJZD 4X5JA 4LAEX 3NZ9X 4H97A 1PD9A 1RX4A 2O7PA 2LF1A 3QLYA 4KM2A 3SRUX 2D0KA 4XE6X 2HXVA 7DFRA 4KJKA 2BLAA 1DREA 2W9TA 1IA3A 4HA7A 4ELHA 4G3MA 2ANOA 3DRCA 4M6KA 1OHJA 4XT8A 4QI9A 1RA2A 4ELFA 3ZPGA 4PSSA 1VDRA 1E26A 1CD2A 3FQCA 3NXVA 3NXYA 3DL5A 3DATA 1HFRA 1AO8A 2W9GA 3FS6A 5CCCA 2XW7A 3NXOA 3IX9A 4ELEA 1PDBA 3JW5A 1RB3A 1HFQA 3QLZA 1RX8A 4I1NA 1DISA 1AI9A 1DDSA 1DG7A 3GHVA 2DRCA 3F8YA 4KBNA 3IA5A 1DYJA 4KFJA 1DR3A 1RF7A 1MVSA 1DR5A 1S3VA 1S3YA 2HM9A 2L28A 5ECXA 1KMVA 3TQ8A 4P3QA 3UM8A 2FZJA 2D5NA 4HOGA 4XECX 3GHWA 1BZFA 3DFRA 2B3ZA 1M7AA 1CZ3A 3JVXA 1DAJA 3D84X 4X5FA 4QHVA 4PSYA 4M7UA 2W3VA 4EJ1A 3F8ZA 4Q0DA 4EIGA 2C2SA 4X5IA 2ZZAA 4IXGX 1RC4A 3F91A 1PD8A 4KD7A 3EX8A 5HF2X 4KAKA 4P68A 2DHFA 3GI2A 3CLBA 5HT5A 4Q67A 4OR7A 5DXVA 3QLRA 1RA3A 4LAGX 3K2HA 3JWMA 4RGCA 3D80A 1RX2A 4OSGA 3SQYX 1QZFA 1RX9A 3SR5X 3SRQX 3SRWX 2W3AA 4I13A 2C2TA 4XT4A 2ITHA 5HQYA 4H95A 5HUIA 4HOFA 1J3IA 3EEJA 4LAHX 4XT7A 4KEBA 4QLEA 2INQA 2W9SA 3LG4A 1HFPA 1RX1A 3RG9A 3OCHA 4KNEA 5ECCA 1DG5A 1TDRA 3QGTA 1JOMA 5HF0X 5HQZA 3RO9A 3S3VA 3EEKA 3ZPCA 4NX7A 3FRBX 3NU0A 1U70A 4XRBA 3JWFA 3NTZA 1LUDA 4LEKX 1BOZA 2HQPA 5JA3A 4NX6A 3S7AA 2CD2A 1ZDRA 1DRFA 1SEJA 3SAIA 1DIUA 3FY8X 1OHKA 2W3MA 4PTJA 3SA1A 3I3RA 3FQFA 3NRRA 4KL9A 1AOEA 5HSRA 3F0SX 3JW3A 3FRDX 3E0BA 4PDJA 4ECKA 1U72A 1DHFA 2GD9A 3K45A 4EILA 3SGYA 3CL9A 4PTHA 4XT6A 3QFXA 3JSUA 3TD8A 2H2QA 3KFYA 3QLWA 2ANQA 1U71A 3INVA 4H98A 1DRAA 4TU5X 5HI6A 3QG2A 3QLXA 4M7VA 3M09A 1RX6A 3CD2A 4DPHA 3FQOA 2BLCA 3FQVA 3NZDA 1DG8A 1DF7A 3F0VX 4HA9A 1RB2A 1S3UA 4G95A 1RE7A 2CIGA 5HVEA 4M6JA 4DDRA 2W3BA 5HT4A 1JOLA 3K47A 1RH3A 1LY3A 3JTWA 3EIGA 3FRAX 1RX5A 3UM5A 3F0QX 3NZCX 3NZAX 3IA4A 5U27A 4HOEA 1RA8A 3DAUA 4QLGA 3NZ6X 4ELBA 1DDRA 2FZHA 1DRHA 3FY9X 3QL3A 4H96A 1IA1A 3CSEA 5EAJA 4FGGA 3NXRA 3HBBA 4P66A 4ELGA 4DFRA 3QL0A 1YHOA 3SRRX 3QYOA 3GHCA 3K74A 3EEMA 4DP3A 2BLBA 3TQ9A 1RG7A 3NZBX 1DHIA 1DR7A 4M2XA 4KYAA 5HVBA 5HPBA 4QLFA 3F0XX 3F0BX 4KLXA 3JWKA 4DPDA 3KJSA 1DYIA 3DL6A 1KLKA 2OBCA 3QLSA 3TQAA 4FHBA 4GH8A 5U26A 3VCOA 1MVTA 1DR2A 3QYLA 4X5GA 3FQZA 3S9UA 3DG8A 4KY8A 5DFRA 3FYVX 2QK8A 1M78A 3FL8A 3IRNA 3ROAA 1LY4A 2JYBA 2P4GA 3Q1HA 1RD7A 3M08A 4KM0A 1DLRA 3HJ3A 3TQBA 1DLSA 1IA2A 2AZNA 1DHJA 4CD2A 4KJJA 3FL9A 2BL9A 4EIZA 1DRBA 3NXXA 1J3JA 5E8QA 1IA4A 3L3RA 3IRMA 3SH2A 3KY8A 3F0UX 1RX3A 1DR1A 3SRSX 4P3RA 3UM6A 1DR6A 1D1GA 4G8ZX 4Q6AA 5JG0X 1VJ3A 1KMSA 4KY4A 4Q0EA 1RA1A 2W3WA 5CC9A 1RA9A 3IROA 4IXFX 4M6LA 4X5HA 4XT5A 1DR4A 3JWCA 1RX7A 3FQ0A 2W9HA 6DFRA 1J3KA 3SA2A 3EELA 3GYFA 2KGKA 2FZIA 3N0HA 3OAFA 5HSUA 1JUVA 3FYWX 4QJCA 8DFRA 3DGAA 4IXED 3FREX 5FDAA 3NXTA 4FGHA 1DYHA 3KJRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FRF X;  2OIP A;  1DYR A;  3KGY A;  1S3W A;  2G6V A;  3I8A X;  4KJL A;  4PST A;  3R33 A;  1M79 A;  4QJZ D;  4X5J A;  4LAE X;  3NZ9 X;  4H97 A;  1PD9 A;  1RX4 A;  2O7P A;  2LF1 A;  3QLY A;  4KM2 A;  3SRU X;  2D0K A;  4XE6 X;  2HXV A;  7DFR A;  4KJK A;  2BLA A;  1DRE A;  2W9T A;  1IA3 A;  4HA7 A;  4ELH A;  4G3M A;  2ANO A;  3DRC A;  4M6K A;  1OHJ A;  4XT8 A;  4QI9 A;  1RA2 A;  4ELF A;  3ZPG A;  4PSS A;  1VDR A;  1E26 A;  1CD2 A;  3FQC A;  3NXV A;  3NXY A;  3DL5 A;  3DAT A;  1HFR A;  1AO8 A;  2W9G A;  3FS6 A;  5CCC A;  2XW7 A;  3NXO A;  3IX9 A;  4ELE A;  1PDB A;  3JW5 A;  1RB3 A;  1HFQ A;  3QLZ A;  1RX8 A;  4I1N A;  1DIS A;  1AI9 A;  1DDS A;  1DG7 A;  3GHV A;  2DRC A;  3F8Y A;  4KBN A;  3IA5 A;  1DYJ A;  4KFJ A;  1DR3 A;  1RF7 A;  1MVS A;  1DR5 A;  1S3V A;  1S3Y A;  2HM9 A;  2L28 A;  5ECX A;  1KMV A;  3TQ8 A;  4P3Q A;  3UM8 A;  2FZJ A;  2D5N A;  4HOG A;  4XEC X;  3GHW A;  1BZF A;  3DFR A;  2B3Z A;  1M7A A;  1CZ3 A;  3JVX A;  1DAJ A;  3D84 X;  4X5F A;  4QHV A;  4PSY A;  4M7U A;  2W3V A;  4EJ1 A;  3F8Z A;  4Q0D A;  4EIG A;  2C2S A;  4X5I A;  2ZZA A;  4IXG X;  1RC4 A;  3F91 A;  1PD8 A;  4KD7 A;  3EX8 A;  5HF2 X;  4KAK A;  4P68 A;  2DHF A;  3GI2 A;  3CLB A;  5HT5 A;  4Q67 A;  4OR7 A;  5DXV A;  3QLR A;  1RA3 A;  4LAG X;  3K2H A;  3JWM A;  4RGC A;  3D80 A;  1RX2 A;  4OSG A;  3SQY X;  1QZF A;  1RX9 A;  3SR5 X;  3SRQ X;  3SRW X;  2W3A A;  4I13 A;  2C2T A;  4XT4 A;  2ITH A;  5HQY A;  4H95 A;  5HUI A;  4HOF A;  1J3I A;  3EEJ A;  4LAH X;  4XT7 A;  4KEB A;  4QLE A;  2INQ A;  2W9S A;  3LG4 A;  1HFP A;  1RX1 A;  3RG9 A;  3OCH A;  4KNE A;  5ECC A;  1DG5 A;  1TDR A;  3QGT A;  1JOM A;  5HF0 X;  5HQZ A;  3RO9 A;  3S3V A;  3EEK A;  3ZPC A;  4NX7 A;  3FRB X;  3NU0 A;  1U70 A;  4XRB A;  3JWF A;  3NTZ A;  1LUD A;  4LEK X;  1BOZ A;  2HQP A;  5JA3 A;  4NX6 A;  3S7A A;  2CD2 A;  1ZDR A;  1DRF A;  1SEJ A;  3SAI A;  1DIU A;  3FY8 X;  1OHK A;  2W3M A;  4PTJ A;  3SA1 A;  3I3R A;  3FQF A;  3NRR A;  4KL9 A;  1AOE A;  5HSR A;  3F0S X;  3JW3 A;  3FRD X;  3E0B A;  4PDJ A;  4ECK A;  1U72 A;  1DHF A;  2GD9 A;  3K45 A;  4EIL A;  3SGY A;  3CL9 A;  4PTH A;  4XT6 A;  3QFX A;  3JSU A;  3TD8 A;  2H2Q A;  3KFY A;  3QLW A;  2ANQ A;  1U71 A;  3INV A;  4H98 A;  1DRA A;  4TU5 X;  5HI6 A;  3QG2 A;  3QLX A;  4M7V A;  3M09 A;  1RX6 A;  3CD2 A;  4DPH A;  3FQO A;  2BLC A;  3FQV A;  3NZD A;  1DG8 A;  1DF7 A;  3F0V X;  4HA9 A;  1RB2 A;  1S3U A;  4G95 A;  1RE7 A;  2CIG A;  5HVE A;  4M6J A;  4DDR A;  2W3B A;  5HT4 A;  1JOL A;  3K47 A;  1RH3 A;  1LY3 A;  3JTW A;  3EIG A;  3FRA X;  1RX5 A;  3UM5 A;  3F0Q X;  3NZC X;  3NZA X;  3IA4 A;  5U27 A;  4HOE A;  1RA8 A;  3DAU A;  4QLG A;  3NZ6 X;  4ELB A;  1DDR A;  2FZH A;  1DRH A;  3FY9 X;  3QL3 A;  4H96 A;  1IA1 A;  3CSE A;  5EAJ A;  4FGG A;  3NXR A;  3HBB A;  4P66 A;  4ELG A;  4DFR A;  3QL0 A;  1YHO A;  3SRR X;  3QYO A;  3GHC A;  3K74 A;  3EEM A;  4DP3 A;  2BLB A;  3TQ9 A;  1RG7 A;  3NZB X;  1DHI A;  1DR7 A;  4M2X A;  4KYA A;  5HVB A;  5HPB A;  4QLF A;  3F0X X;  3F0B X;  4KLX A;  3JWK A;  4DPD A;  3KJS A;  1DYI A;  3DL6 A;  1KLK A;  2OBC A;  3QLS A;  3TQA A;  4FHB A;  4GH8 A;  5U26 A;  3VCO A;  1MVT A;  1DR2 A;  3QYL A;  4X5G A;  3FQZ A;  3S9U A;  3DG8 A;  4KY8 A;  5DFR A;  3FYV X;  2QK8 A;  1M78 A;  3FL8 A;  3IRN A;  3ROA A;  1LY4 A;  2JYB A;  2P4G A;  3Q1H A;  1RD7 A;  3M08 A;  4KM0 A;  1DLR A;  3HJ3 A;  3TQB A;  1DLS A;  1IA2 A;  2AZN A;  1DHJ A;  4CD2 A;  4KJJ A;  3FL9 A;  2BL9 A;  4EIZ A;  1DRB A;  3NXX A;  1J3J A;  5E8Q A;  1IA4 A;  3L3R A;  3IRM A;  3SH2 A;  3KY8 A;  3F0U X;  1RX3 A;  1DR1 A;  3SRS X;  4P3R A;  3UM6 A;  1DR6 A;  1D1G A;  4G8Z X;  4Q6A A;  5JG0 X;  1VJ3 A;  1KMS A;  4KY4 A;  4Q0E A;  1RA1 A;  2W3W A;  5CC9 A;  1RA9 A;  3IRO A;  4IXF X;  4M6L A;  4X5H A;  4XT5 A;  1DR4 A;  3JWC A;  1RX7 A;  3FQ0 A;  2W9H A;  6DFR A;  1J3K A;  3SA2 A;  3EEL A;  3GYF A;  2KGK A;  2FZI A;  3N0H A;  3OAF A;  5HSU A;  1JUV A;  3FYW X;  4QJC A;  8DFR A;  3DGA A;  4IXE D;  3FRE X;  5FDA A;  3NXT A;  4FGH A;  1DYH A;  3KJR A; 
#chains in the Genus database with same CATH topology
 3FRF X;  2OIP A;  1DYR A;  3KGY A;  1S3W A;  2G6V A;  3I8A X;  4KJL A;  4PST A;  3R33 A;  1M79 A;  4QJZ D;  4X5J A;  4LAE X;  3NZ9 X;  4H97 A;  1PD9 A;  1RX4 A;  2O7P A;  2LF1 A;  3QLY A;  4KM2 A;  3SRU X;  2D0K A;  4XE6 X;  2HXV A;  7DFR A;  4KJK A;  2BLA A;  1DRE A;  2W9T A;  1IA3 A;  4HA7 A;  4ELH A;  4G3M A;  2ANO A;  3DRC A;  4M6K A;  1OHJ A;  4XT8 A;  4QI9 A;  1RA2 A;  4ELF A;  3ZPG A;  4PSS A;  1VDR A;  1E26 A;  1CD2 A;  3FQC A;  3NXV A;  3NXY A;  3DL5 A;  3DAT A;  1HFR A;  1AO8 A;  2W9G A;  3FS6 A;  5CCC A;  2XW7 A;  3NXO A;  3IX9 A;  4ELE A;  1PDB A;  3JW5 A;  1RB3 A;  1HFQ A;  3QLZ A;  1RX8 A;  4I1N A;  1DIS A;  1AI9 A;  1DDS A;  1DG7 A;  3GHV A;  2DRC A;  3F8Y A;  4KBN A;  3IA5 A;  1DYJ A;  4KFJ A;  1DR3 A;  1RF7 A;  1MVS A;  1DR5 A;  1S3V A;  1S3Y A;  2HM9 A;  2L28 A;  5ECX A;  1KMV A;  3TQ8 A;  4P3Q A;  3UM8 A;  2FZJ A;  2D5N A;  4HOG A;  4XEC X;  3GHW A;  1BZF A;  3DFR A;  2B3Z A;  1M7A A;  1CZ3 A;  3JVX A;  1DAJ A;  3D84 X;  4X5F A;  4QHV A;  4PSY A;  4M7U A;  2W3V A;  4EJ1 A;  3F8Z A;  4Q0D A;  4EIG A;  2C2S A;  4X5I A;  2ZZA A;  4IXG X;  1RC4 A;  3F91 A;  1PD8 A;  4KD7 A;  3EX8 A;  5HF2 X;  4KAK A;  4P68 A;  2DHF A;  3GI2 A;  3CLB A;  5HT5 A;  4Q67 A;  4OR7 A;  5DXV A;  3QLR A;  1RA3 A;  4LAG X;  3K2H A;  3JWM A;  4RGC A;  3D80 A;  1RX2 A;  4OSG A;  3SQY X;  1QZF A;  1RX9 A;  3SR5 X;  3SRQ X;  3SRW X;  2W3A A;  4I13 A;  2C2T A;  4XT4 A;  2ITH A;  5HQY A;  4H95 A;  5HUI A;  4HOF A;  1J3I A;  3EEJ A;  4LAH X;  4XT7 A;  4KEB A;  4QLE A;  2INQ A;  2W9S A;  3LG4 A;  1HFP A;  1RX1 A;  3RG9 A;  3OCH A;  4KNE A;  5ECC A;  1DG5 A;  1TDR A;  3QGT A;  1JOM A;  5HF0 X;  5HQZ A;  3RO9 A;  3S3V A;  3EEK A;  3ZPC A;  4NX7 A;  3FRB X;  3NU0 A;  1U70 A;  4XRB A;  3JWF A;  3NTZ A;  1LUD A;  4LEK X;  1BOZ A;  2HQP A;  5JA3 A;  4NX6 A;  3S7A A;  2CD2 A;  1ZDR A;  1DRF A;  1SEJ A;  3SAI A;  1DIU A;  3FY8 X;  1OHK A;  2W3M A;  4PTJ A;  3SA1 A;  3I3R A;  3FQF A;  3NRR A;  4KL9 A;  1AOE A;  5HSR A;  3F0S X;  3JW3 A;  3FRD X;  3E0B A;  4PDJ A;  4ECK A;  1U72 A;  1DHF A;  2GD9 A;  3K45 A;  4EIL A;  3SGY A;  3CL9 A;  4PTH A;  4XT6 A;  3QFX A;  3JSU A;  3TD8 A;  2H2Q A;  3KFY A;  3QLW A;  2ANQ A;  1U71 A;  3INV A;  4H98 A;  1DRA A;  4TU5 X;  5HI6 A;  3QG2 A;  3QLX A;  4M7V A;  3M09 A;  1RX6 A;  3CD2 A;  4DPH A;  3FQO A;  2BLC A;  3FQV A;  3NZD A;  1DG8 A;  1DF7 A;  3F0V X;  4HA9 A;  1RB2 A;  1S3U A;  4G95 A;  1RE7 A;  2CIG A;  5HVE A;  4M6J A;  4DDR A;  2W3B A;  5HT4 A;  1JOL A;  3K47 A;  1RH3 A;  1LY3 A;  3JTW A;  3EIG A;  3FRA X;  1RX5 A;  3UM5 A;  3F0Q X;  3NZC X;  3NZA X;  3IA4 A;  5U27 A;  4HOE A;  1RA8 A;  3DAU A;  4QLG A;  3NZ6 X;  4ELB A;  1DDR A;  2FZH A;  1DRH A;  3FY9 X;  3QL3 A;  4H96 A;  1IA1 A;  3CSE A;  5EAJ A;  4FGG A;  3NXR A;  3HBB A;  4P66 A;  4ELG A;  4DFR A;  3QL0 A;  1YHO A;  3SRR X;  3QYO A;  3GHC A;  3K74 A;  3EEM A;  4DP3 A;  2BLB A;  3TQ9 A;  1RG7 A;  3NZB X;  1DHI A;  1DR7 A;  4M2X A;  4KYA A;  5HVB A;  5HPB A;  4QLF A;  3F0X X;  3F0B X;  4KLX A;  3JWK A;  4DPD A;  3KJS A;  1DYI A;  3DL6 A;  1KLK A;  2OBC A;  3QLS A;  3TQA A;  4FHB A;  4GH8 A;  5U26 A;  3VCO A;  1MVT A;  1DR2 A;  3QYL A;  4X5G A;  3FQZ A;  3S9U A;  3DG8 A;  4KY8 A;  5DFR A;  3FYV X;  2QK8 A;  1M78 A;  3FL8 A;  3IRN A;  3ROA A;  1LY4 A;  2JYB A;  2P4G A;  3Q1H A;  1RD7 A;  3M08 A;  4KM0 A;  1DLR A;  3HJ3 A;  3TQB A;  1DLS A;  1IA2 A;  2AZN A;  1DHJ A;  4CD2 A;  4KJJ A;  3FL9 A;  2BL9 A;  4EIZ A;  1DRB A;  3NXX A;  1J3J A;  5E8Q A;  1IA4 A;  3L3R A;  3IRM A;  3SH2 A;  3KY8 A;  3F0U X;  1RX3 A;  1DR1 A;  3SRS X;  4P3R A;  3UM6 A;  1DR6 A;  1D1G A;  4G8Z X;  4Q6A A;  5JG0 X;  1VJ3 A;  1KMS A;  4KY4 A;  4Q0E A;  1RA1 A;  2W3W A;  5CC9 A;  1RA9 A;  3IRO A;  4IXF X;  4M6L A;  4X5H A;  4XT5 A;  1DR4 A;  3JWC A;  1RX7 A;  3FQ0 A;  2W9H A;  6DFR A;  1J3K A;  3SA2 A;  3EEL A;  3GYF A;  2KGK A;  2FZI A;  3N0H A;  3OAF A;  5HSU A;  1JUV A;  3FYW X;  4QJC A;  8DFR A;  3DGA A;  4IXE D;  3FRE X;  5FDA A;  3NXT A;  4FGH A;  1DYH A;  3KJR A; 
#chains in the Genus database with same CATH homology
 3FRF X;  2OIP A;  1DYR A;  3KGY A;  1S3W A;  2G6V A;  3I8A X;  4KJL A;  4PST A;  3R33 A;  1M79 A;  4QJZ D;  4X5J A;  4LAE X;  3NZ9 X;  4H97 A;  1PD9 A;  1RX4 A;  2O7P A;  2LF1 A;  3QLY A;  4KM2 A;  3SRU X;  2D0K A;  4XE6 X;  2HXV A;  7DFR A;  4KJK A;  2BLA A;  1DRE A;  2W9T A;  1IA3 A;  4HA7 A;  4ELH A;  4G3M A;  2ANO A;  3DRC A;  4M6K A;  1OHJ A;  4XT8 A;  4QI9 A;  1RA2 A;  4ELF A;  3ZPG A;  4PSS A;  1VDR A;  1E26 A;  1CD2 A;  3FQC A;  3NXV A;  3NXY A;  3DL5 A;  3DAT A;  1HFR A;  1AO8 A;  2W9G A;  3FS6 A;  5CCC A;  2XW7 A;  3NXO A;  3IX9 A;  4ELE A;  1PDB A;  3JW5 A;  1RB3 A;  1HFQ A;  3QLZ A;  1RX8 A;  4I1N A;  1DIS A;  1AI9 A;  1DDS A;  1DG7 A;  3GHV A;  2DRC A;  3F8Y A;  4KBN A;  3IA5 A;  1DYJ A;  4KFJ A;  1DR3 A;  1RF7 A;  1MVS A;  1DR5 A;  1S3V A;  1S3Y A;  2HM9 A;  2L28 A;  5ECX A;  1KMV A;  3TQ8 A;  4P3Q A;  3UM8 A;  2FZJ A;  2D5N A;  4HOG A;  4XEC X;  3GHW A;  1BZF A;  3DFR A;  2B3Z A;  1M7A A;  1CZ3 A;  3JVX A;  1DAJ A;  3D84 X;  4X5F A;  4QHV A;  4PSY A;  4M7U A;  2W3V A;  4EJ1 A;  3F8Z A;  4Q0D A;  4EIG A;  2C2S A;  4X5I A;  2ZZA A;  4IXG X;  1RC4 A;  3F91 A;  1PD8 A;  4KD7 A;  3EX8 A;  5HF2 X;  4KAK A;  4P68 A;  2DHF A;  3GI2 A;  3CLB A;  5HT5 A;  4Q67 A;  4OR7 A;  5DXV A;  3QLR A;  1RA3 A;  4LAG X;  3K2H A;  3JWM A;  4RGC A;  3D80 A;  1RX2 A;  4OSG A;  3SQY X;  1QZF A;  1RX9 A;  3SR5 X;  3SRQ X;  3SRW X;  2W3A A;  4I13 A;  2C2T A;  4XT4 A;  2ITH A;  5HQY A;  4H95 A;  5HUI A;  4HOF A;  1J3I A;  3EEJ A;  4LAH X;  4XT7 A;  4KEB A;  4QLE A;  2INQ A;  2W9S A;  3LG4 A;  1HFP A;  1RX1 A;  3RG9 A;  3OCH A;  4KNE A;  5ECC A;  1DG5 A;  1TDR A;  3QGT A;  1JOM A;  5HF0 X;  5HQZ A;  3RO9 A;  3S3V A;  3EEK A;  3ZPC A;  4NX7 A;  3FRB X;  3NU0 A;  1U70 A;  4XRB A;  3JWF A;  3NTZ A;  1LUD A;  4LEK X;  1BOZ A;  2HQP A;  5JA3 A;  4NX6 A;  3S7A A;  2CD2 A;  1ZDR A;  1DRF A;  1SEJ A;  3SAI A;  1DIU A;  3FY8 X;  1OHK A;  2W3M A;  4PTJ A;  3SA1 A;  3I3R A;  3FQF A;  3NRR A;  4KL9 A;  1AOE A;  5HSR A;  3F0S X;  3JW3 A;  3FRD X;  3E0B A;  4PDJ A;  4ECK A;  1U72 A;  1DHF A;  2GD9 A;  3K45 A;  4EIL A;  3SGY A;  3CL9 A;  4PTH A;  4XT6 A;  3QFX A;  3JSU A;  3TD8 A;  2H2Q A;  3KFY A;  3QLW A;  2ANQ A;  1U71 A;  3INV A;  4H98 A;  1DRA A;  4TU5 X;  5HI6 A;  3QG2 A;  3QLX A;  4M7V A;  3M09 A;  1RX6 A;  3CD2 A;  4DPH A;  3FQO A;  2BLC A;  3FQV A;  3NZD A;  1DG8 A;  1DF7 A;  3F0V X;  4HA9 A;  1RB2 A;  1S3U A;  4G95 A;  1RE7 A;  2CIG A;  5HVE A;  4M6J A;  4DDR A;  2W3B A;  5HT4 A;  1JOL A;  3K47 A;  1RH3 A;  1LY3 A;  3JTW A;  3EIG A;  3FRA X;  1RX5 A;  3UM5 A;  3F0Q X;  3NZC X;  3NZA X;  3IA4 A;  5U27 A;  4HOE A;  1RA8 A;  3DAU A;  4QLG A;  3NZ6 X;  4ELB A;  1DDR A;  2FZH A;  1DRH A;  3FY9 X;  3QL3 A;  4H96 A;  1IA1 A;  3CSE A;  5EAJ A;  4FGG A;  3NXR A;  3HBB A;  4P66 A;  4ELG A;  4DFR A;  3QL0 A;  1YHO A;  3SRR X;  3QYO A;  3GHC A;  3K74 A;  3EEM A;  4DP3 A;  2BLB A;  3TQ9 A;  1RG7 A;  3NZB X;  1DHI A;  1DR7 A;  4M2X A;  4KYA A;  5HVB A;  5HPB A;  4QLF A;  3F0X X;  3F0B X;  4KLX A;  3JWK A;  4DPD A;  3KJS A;  1DYI A;  3DL6 A;  1KLK A;  2OBC A;  3QLS A;  3TQA A;  4FHB A;  4GH8 A;  5U26 A;  3VCO A;  1MVT A;  1DR2 A;  3QYL A;  4X5G A;  3FQZ A;  3S9U A;  3DG8 A;  4KY8 A;  5DFR A;  3FYV X;  2QK8 A;  1M78 A;  3FL8 A;  3IRN A;  3ROA A;  1LY4 A;  2JYB A;  2P4G A;  3Q1H A;  1RD7 A;  3M08 A;  4KM0 A;  1DLR A;  3HJ3 A;  3TQB A;  1DLS A;  1IA2 A;  2AZN A;  1DHJ A;  4CD2 A;  4KJJ A;  3FL9 A;  2BL9 A;  4EIZ A;  1DRB A;  3NXX A;  1J3J A;  5E8Q A;  1IA4 A;  3L3R A;  3IRM A;  3SH2 A;  3KY8 A;  3F0U X;  1RX3 A;  1DR1 A;  3SRS X;  4P3R A;  3UM6 A;  1DR6 A;  1D1G A;  4G8Z X;  4Q6A A;  5JG0 X;  1VJ3 A;  1KMS A;  4KY4 A;  4Q0E A;  1RA1 A;  2W3W A;  5CC9 A;  1RA9 A;  3IRO A;  4IXF X;  4M6L A;  4X5H A;  4XT5 A;  1DR4 A;  3JWC A;  1RX7 A;  3FQ0 A;  2W9H A;  6DFR A;  1J3K A;  3SA2 A;  3EEL A;  3GYF A;  2KGK A;  2FZI A;  3N0H A;  3OAF A;  5HSU A;  1JUV A;  3FYW X;  4QJC A;  8DFR A;  3DGA A;  4IXE D;  3FRE X;  5FDA A;  3NXT A;  4FGH A;  1DYH A;  3KJR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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