3KFYA

Dynamic switching and partial occupancies of a small molecule inhibitor complex of dhfr
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR
rcsb
molecule tags Oxidoreductase
molecule keywords Dihydrofolate reductase
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2009-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3kfyA00
3NXRA 3OAFA 4DPHA 1DR1A 3F0QX 3FREX 3FQVA 3ROAA 1CZ3A 3RO9A 4I13A 1DRHA 3F0XX 1RX9A 1RA1A 4TU5X 1RA2A 4ELHA 5HF2X 3KJSA 1IA3A 3VCOA 1RX4A 4LAEX 3EEJA 4EIZA 3EELA 3INVA 4KLXA 4IXFX 4NX6A 1DYRA 1RA3A 1LY3A 1RF7A 5U27A 5HF0X 3IX9A 2D0KA 2BLCA 5HUIA 3FQFA 3UM8A 1DG7A 3TQAA 1SEJA 2W3VA 3JWKA 3FY8X 1RX3A 3S7AA 3EEKA 2DHFA 1KMSA 5EAJA 1MVSA 1DRBA 3FYWX 3DL6A 4P68A 4XECX 2W3WA 3EX8A 1KLKA 3ZPCA 4OSGA 3SRUX 1DR7A 2L28A 3NXYA 4H98A 5HQZA 2O7PA 6DFRA 2INQA 3NZBX 1HFQA 1LY4A 3HJ3A 3TQ8A 2BLAA 2JYBA 3JWMA 4G8ZX 3NZAX 1PD9A 2QK8A 3OCHA 1RE7A 2C2SA 3KJRA 1DHFA 3UM5A 4QI9A 4LAHX 4KAKA 3DGAA 2BL9A 1J3KA 4DDRA 3LG4A 1S3VA 1U70A 3SR5X 1DR2A 3GHWA 3D80A 5JG0X 4KFJA 3S9UA 1DYHA 3NZCX 3E0BA 1DG5A 2ANOA 1S3WA 2W9SA 3NZDA 1DYIA 4ECKA 3TD8A 4QLEA 3RG9A 1AOEA 5ECXA 1JOLA 3QLRA 3GI2A 1RG7A 3NXVA 3R33A 1DLRA 2ZZAA 3IRMA 3FQCA 4ELEA 1JOMA 3NXTA 1RA8A 4ELBA 4X5JA 4X5IA 2LF1A 1YHOA 1RB3A 3CSEA 4P3RA 1HFPA 4G95A 2XW7A 1S3UA 3FYVX 4H95A 3QLWA 2OIPA 3DAUA 1DHIA 4X5HA 1RX1A 5HVBA 1KMVA 4G3MA 4DFRA 5DFRA 4KD7A 4RGCA 3GHCA 3GYFA 1RD7A 2DRCA 3CL9A 8DFRA 1RC4A 1RX2A 4KY4A 4XT4A 3F8YA 5HI6A 1JUVA 2D5NA 3DRCA 3SH2A 4XT6A 4P3QA 4OR7A 1D1GA 3NZ6X 4KNEA 1M7AA 1IA2A 4Q0DA 1DR5A 2HM9A 4FHBA 2P4GA 1DF7A 3QL0A 4IXGX 3DG8A 2AZNA 4Q0EA 3KGYA 3FRFX 1VDRA 5CCCA 5JA3A 1LUDA 2W3MA 2W9HA 3NU0A 3F0BX 2BLBA 5HQYA 1RH3A 5U26A 5FDAA 4QHVA 3JWCA 4QJCA 2KGKA 5DXVA 5HT4A 2GD9A 3I3RA 4FGGA 1RA9A 5HSUA 3N0HA 1DREA 4ELFA 3M08A 3DFRA 3JW5A 4QJZD 4HA9A 3TQBA 4M6LA 3QLYA 3QYLA 2ITHA 3QG2A 3NXOA 1AI9A 5HSRA 3I8AX 3QLSA 3S3VA 4FGHA 3QGTA 3SRSX 3NRRA 4XT8A 3KFYA 1DRAA 3K74A 3TQ9A 7DFRA 3FS6A 3ZPGA 4HOFA 4M6KA 5ECCA 3SRQX 3F8ZA 4H97A 3F0VX 1E26A 1PD8A 3SQYX 2W9GA 3HBBA 3UM6A 4XT5A 3JW3A 1DYJA 1J3JA 1J3IA 5HPBA 4KY8A 4PTJA 3IA4A 1BZFA 3QLZA 2CD2A 3SA1A 1S3YA 3SRRX 4M7UA 4EJ1A 1DHJA 3JSUA 3FQOA 1OHKA 3NXXA 3SGYA 3SA2A 3K45A 3QLXA 4HOEA 3FQZA 4XE6X 1RX5A 4KM2A 1PDBA 3CD2A 5HVEA 4PSYA 2FZHA 4KJJA 1DDSA 4I1NA 4KJLA 3F91A 3QYOA 2FZIA 4X5FA 4HA7A 1RX6A 4NX7A 4KEBA 2W3AA 3FRBX 3FL9A 1IA4A 3IRNA 4KJKA 4HOGA 3EIGA 2W3BA 1M78A 4M6JA 4PDJA 3KY8A 3CLBA 4QLGA 1RX8A 1DR4A 3K47A 1CD2A 3Q1HA 4EIGA 3FRAX 1HFRA 4CD2A 1OHJA 4M2XA 1BOZA 3EEMA 4ELGA 3QFXA 4Q6AA 3FL8A 3GHVA 2G6VA 5CC9A 4QLFA 2W9TA 1RX7A 3IROA 3FRDX 2ANQA 4M7VA 1AO8A 1ZDRA 2C2TA 3DATA 1DR3A 2B3ZA 4P66A 1DRFA 3JVXA 3FY9X 1VJ3A 4EILA 3NZ9X 3F0UX 4XRBA 3JWFA 3M09A 4DPDA 4LEKX 4KL9A 2HXVA 1U71A 4IXED 3NTZA 4X5GA 1MVTA 1DDRA 1IA1A 5HT5A 3FQ0A 4KYAA 4GH8A 1U72A 1DAJA 3K2HA 4Q67A 1DISA 4KBNA 4LAGX 3SAIA 4XT7A 3IA5A 4PTHA 4PSTA 4PSSA 1M79A 3F0SX 1DIUA 2H2QA 1RB2A 1DR6A 3D84X 2HQPA 1DLSA 5E8QA 3JTWA 2FZJA 3L3RA 1TDRA 1DG8A 1QZFA 4KM0A 3QL3A 3SRWX 4DP3A 4H96A 2CIGA 3DL5A 2OBCA
chains in the Genus database with same CATH superfamily
3NXRA 3OAFA 4DPHA 1DR1A 3F0QX 3FREX 3FQVA 3ROAA 1CZ3A 3RO9A 4I13A 1DRHA 3F0XX 1RX9A 1RA1A 4TU5X 1RA2A 4ELHA 5HF2X 3KJSA 1IA3A 3VCOA 1RX4A 4LAEX 3EEJA 4EIZA 3EELA 3INVA 4KLXA 4IXFX 4NX6A 1DYRA 1RA3A 1LY3A 1RF7A 5U27A 5HF0X 3IX9A 2D0KA 2BLCA 5HUIA 3FQFA 3UM8A 1DG7A 3TQAA 1SEJA 2W3VA 3JWKA 3FY8X 1RX3A 3S7AA 3EEKA 2DHFA 1KMSA 5EAJA 1MVSA 1DRBA 3FYWX 3DL6A 4P68A 4XECX 2W3WA 3EX8A 1KLKA 3ZPCA 4OSGA 3SRUX 1DR7A 2L28A 3NXYA 4H98A 5HQZA 2O7PA 6DFRA 2INQA 3NZBX 1HFQA 1LY4A 3HJ3A 3TQ8A 2BLAA 2JYBA 3JWMA 4G8ZX 3NZAX 1PD9A 2QK8A 3OCHA 1RE7A 2C2SA 3KJRA 1DHFA 3UM5A 4QI9A 4LAHX 4KAKA 3DGAA 2BL9A 1J3KA 4DDRA 3LG4A 1S3VA 1U70A 3SR5X 1DR2A 3GHWA 3D80A 5JG0X 4KFJA 3S9UA 1DYHA 3NZCX 3E0BA 1DG5A 2ANOA 1S3WA 2W9SA 3NZDA 1DYIA 4ECKA 3TD8A 4QLEA 3RG9A 1AOEA 5ECXA 1JOLA 3QLRA 3GI2A 1RG7A 3NXVA 3R33A 1DLRA 2ZZAA 3IRMA 3FQCA 4ELEA 1JOMA 3NXTA 1RA8A 4ELBA 4X5JA 4X5IA 2LF1A 1YHOA 1RB3A 3CSEA 4P3RA 1HFPA 4G95A 2XW7A 1S3UA 3FYVX 4H95A 3QLWA 2OIPA 3DAUA 1DHIA 4X5HA 1RX1A 5HVBA 1KMVA 4G3MA 4DFRA 5DFRA 4KD7A 4RGCA 3GHCA 3GYFA 1RD7A 2DRCA 3CL9A 8DFRA 1RC4A 1RX2A 4KY4A 4XT4A 3F8YA 5HI6A 1JUVA 2D5NA 3DRCA 3SH2A 4XT6A 4P3QA 4OR7A 1D1GA 3NZ6X 4KNEA 1M7AA 1IA2A 4Q0DA 1DR5A 2HM9A 4FHBA 2P4GA 1DF7A 3QL0A 4IXGX 3DG8A 2AZNA 4Q0EA 3KGYA 3FRFX 1VDRA 5CCCA 5JA3A 1LUDA 2W3MA 2W9HA 3NU0A 3F0BX 2BLBA 5HQYA 1RH3A 5U26A 5FDAA 4QHVA 3JWCA 4QJCA 2KGKA 5DXVA 5HT4A 2GD9A 3I3RA 4FGGA 1RA9A 5HSUA 3N0HA 1DREA 4ELFA 3M08A 3DFRA 3JW5A 4QJZD 4HA9A 3TQBA 4M6LA 3QLYA 3QYLA 2ITHA 3QG2A 3NXOA 1AI9A 5HSRA 3I8AX 3QLSA 3S3VA 4FGHA 3QGTA 3SRSX 3NRRA 4XT8A 3KFYA 1DRAA 3K74A 3TQ9A 7DFRA 3FS6A 3ZPGA 4HOFA 4M6KA 5ECCA 3SRQX 3F8ZA 4H97A 3F0VX 1E26A 1PD8A 3SQYX 2W9GA 3HBBA 3UM6A 4XT5A 3JW3A 1DYJA 1J3JA 1J3IA 5HPBA 4KY8A 4PTJA 3IA4A 1BZFA 3QLZA 2CD2A 3SA1A 1S3YA 3SRRX 4M7UA 4EJ1A 1DHJA 3JSUA 3FQOA 1OHKA 3NXXA 3SGYA 3SA2A 3K45A 3QLXA 4HOEA 3FQZA 4XE6X 1RX5A 4KM2A 1PDBA 3CD2A 5HVEA 4PSYA 2FZHA 4KJJA 1DDSA 4I1NA 4KJLA 3F91A 3QYOA 2FZIA 4X5FA 4HA7A 1RX6A 4NX7A 4KEBA 2W3AA 3FRBX 3FL9A 1IA4A 3IRNA 4KJKA 4HOGA 3EIGA 2W3BA 1M78A 4M6JA 4PDJA 3KY8A 3CLBA 4QLGA 1RX8A 1DR4A 3K47A 1CD2A 3Q1HA 4EIGA 3FRAX 1HFRA 4CD2A 1OHJA 4M2XA 1BOZA 3EEMA 4ELGA 3QFXA 4Q6AA 3FL8A 3GHVA 2G6VA 5CC9A 4QLFA 2W9TA 1RX7A 3IROA 3FRDX 2ANQA 4M7VA 1AO8A 1ZDRA 2C2TA 3DATA 1DR3A 2B3ZA 4P66A 1DRFA 3JVXA 3FY9X 1VJ3A 4EILA 3NZ9X 3F0UX 4XRBA 3JWFA 3M09A 4DPDA 4LEKX 4KL9A 2HXVA 1U71A 4IXED 3NTZA 4X5GA 1MVTA 1DDRA 1IA1A 5HT5A 3FQ0A 4KYAA 4GH8A 1U72A 1DAJA 3K2HA 4Q67A 1DISA 4KBNA 4LAGX 3SAIA 4XT7A 3IA5A 4PTHA 4PSTA 4PSSA 1M79A 3F0SX 1DIUA 2H2QA 1RB2A 1DR6A 3D84X 2HQPA 1DLSA 5E8QA 3JTWA 2FZJA 3L3RA 1TDRA 1DG8A 1QZFA 4KM0A 3QL3A 3SRWX 4DP3A 4H96A 2CIGA 3DL5A 2OBCA
chains in the Genus database with same CATH topology
3NXRA 3OAFA 4DPHA 1DR1A 3F0QX 3FREX 3FQVA 3ROAA 1CZ3A 3RO9A 4I13A 1DRHA 3F0XX 1RX9A 1RA1A 4TU5X 1RA2A 4ELHA 5HF2X 3KJSA 1IA3A 3VCOA 1RX4A 4LAEX 3EEJA 4EIZA 3EELA 3INVA 4KLXA 4IXFX 4NX6A 1DYRA 1RA3A 1LY3A 1RF7A 5U27A 5HF0X 3IX9A 2D0KA 2BLCA 5HUIA 3FQFA 3UM8A 1DG7A 3TQAA 1SEJA 2W3VA 3JWKA 3FY8X 1RX3A 3S7AA 3EEKA 2DHFA 1KMSA 5EAJA 1MVSA 1DRBA 3FYWX 3DL6A 4P68A 4XECX 2W3WA 3EX8A 1KLKA 3ZPCA 4OSGA 3SRUX 1DR7A 2L28A 3NXYA 4H98A 5HQZA 2O7PA 6DFRA 2INQA 3NZBX 1HFQA 1LY4A 3HJ3A 3TQ8A 2BLAA 2JYBA 3JWMA 4G8ZX 3NZAX 1PD9A 2QK8A 3OCHA 1RE7A 2C2SA 3KJRA 1DHFA 3UM5A 4QI9A 4LAHX 4KAKA 3DGAA 2BL9A 1J3KA 4DDRA 3LG4A 1S3VA 1U70A 3SR5X 1DR2A 3GHWA 3D80A 5JG0X 4KFJA 3S9UA 1DYHA 3NZCX 3E0BA 1DG5A 2ANOA 1S3WA 2W9SA 3NZDA 1DYIA 4ECKA 3TD8A 4QLEA 3RG9A 1AOEA 5ECXA 1JOLA 3QLRA 3GI2A 1RG7A 3NXVA 3R33A 1DLRA 2ZZAA 3IRMA 3FQCA 4ELEA 1JOMA 3NXTA 1RA8A 4ELBA 4X5JA 4X5IA 2LF1A 1YHOA 1RB3A 3CSEA 4P3RA 1HFPA 4G95A 2XW7A 1S3UA 3FYVX 4H95A 3QLWA 2OIPA 3DAUA 1DHIA 4X5HA 1RX1A 5HVBA 1KMVA 4G3MA 4DFRA 5DFRA 4KD7A 4RGCA 3GHCA 3GYFA 1RD7A 2DRCA 3CL9A 8DFRA 1RC4A 1RX2A 4KY4A 4XT4A 3F8YA 5HI6A 1JUVA 2D5NA 3DRCA 3SH2A 4XT6A 4P3QA 4OR7A 1D1GA 3NZ6X 4KNEA 1M7AA 1IA2A 4Q0DA 1DR5A 2HM9A 4FHBA 2P4GA 1DF7A 3QL0A 4IXGX 3DG8A 2AZNA 4Q0EA 3KGYA 3FRFX 1VDRA 5CCCA 5JA3A 1LUDA 2W3MA 2W9HA 3NU0A 3F0BX 2BLBA 5HQYA 1RH3A 5U26A 5FDAA 4QHVA 3JWCA 4QJCA 2KGKA 5DXVA 5HT4A 2GD9A 3I3RA 4FGGA 1RA9A 5HSUA 3N0HA 1DREA 4ELFA 3M08A 3DFRA 3JW5A 4QJZD 4HA9A 3TQBA 4M6LA 3QLYA 3QYLA 2ITHA 3QG2A 3NXOA 1AI9A 5HSRA 3I8AX 3QLSA 3S3VA 4FGHA 3QGTA 3SRSX 3NRRA 4XT8A 3KFYA 1DRAA 3K74A 3TQ9A 7DFRA 3FS6A 3ZPGA 4HOFA 4M6KA 5ECCA 3SRQX 3F8ZA 4H97A 3F0VX 1E26A 1PD8A 3SQYX 2W9GA 3HBBA 3UM6A 4XT5A 3JW3A 1DYJA 1J3JA 1J3IA 5HPBA 4KY8A 4PTJA 3IA4A 1BZFA 3QLZA 2CD2A 3SA1A 1S3YA 3SRRX 4M7UA 4EJ1A 1DHJA 3JSUA 3FQOA 1OHKA 3NXXA 3SGYA 3SA2A 3K45A 3QLXA 4HOEA 3FQZA 4XE6X 1RX5A 4KM2A 1PDBA 3CD2A 5HVEA 4PSYA 2FZHA 4KJJA 1DDSA 4I1NA 4KJLA 3F91A 3QYOA 2FZIA 4X5FA 4HA7A 1RX6A 4NX7A 4KEBA 2W3AA 3FRBX 3FL9A 1IA4A 3IRNA 4KJKA 4HOGA 3EIGA 2W3BA 1M78A 4M6JA 4PDJA 3KY8A 3CLBA 4QLGA 1RX8A 1DR4A 3K47A 1CD2A 3Q1HA 4EIGA 3FRAX 1HFRA 4CD2A 1OHJA 4M2XA 1BOZA 3EEMA 4ELGA 3QFXA 4Q6AA 3FL8A 3GHVA 2G6VA 5CC9A 4QLFA 2W9TA 1RX7A 3IROA 3FRDX 2ANQA 4M7VA 1AO8A 1ZDRA 2C2TA 3DATA 1DR3A 2B3ZA 4P66A 1DRFA 3JVXA 3FY9X 1VJ3A 4EILA 3NZ9X 3F0UX 4XRBA 3JWFA 3M09A 4DPDA 4LEKX 4KL9A 2HXVA 1U71A 4IXED 3NTZA 4X5GA 1MVTA 1DDRA 1IA1A 5HT5A 3FQ0A 4KYAA 4GH8A 1U72A 1DAJA 3K2HA 4Q67A 1DISA 4KBNA 4LAGX 3SAIA 4XT7A 3IA5A 4PTHA 4PSTA 4PSSA 1M79A 3F0SX 1DIUA 2H2QA 1RB2A 1DR6A 3D84X 2HQPA 1DLSA 5E8QA 3JTWA 2FZJA 3L3RA 1TDRA 1DG8A 1QZFA 4KM0A 3QL3A 3SRWX 4DP3A 4H96A 2CIGA 3DL5A 2OBCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NXR A;  3OAF A;  4DPH A;  1DR1 A;  3F0Q X;  3FRE X;  3FQV A;  3ROA A;  1CZ3 A;  3RO9 A;  4I13 A;  1DRH A;  3F0X X;  1RX9 A;  1RA1 A;  4TU5 X;  1RA2 A;  4ELH A;  5HF2 X;  3KJS A;  1IA3 A;  3VCO A;  1RX4 A;  4LAE X;  3EEJ A;  4EIZ A;  3EEL A;  3INV A;  4KLX A;  4IXF X;  4NX6 A;  1DYR A;  1RA3 A;  1LY3 A;  1RF7 A;  5U27 A;  5HF0 X;  3IX9 A;  2D0K A;  2BLC A;  5HUI A;  3FQF A;  3UM8 A;  1DG7 A;  3TQA A;  1SEJ A;  2W3V A;  3JWK A;  3FY8 X;  1RX3 A;  3S7A A;  3EEK A;  2DHF A;  1KMS A;  5EAJ A;  1MVS A;  1DRB A;  3FYW X;  3DL6 A;  4P68 A;  4XEC X;  2W3W A;  3EX8 A;  1KLK A;  3ZPC A;  4OSG A;  3SRU X;  1DR7 A;  2L28 A;  3NXY A;  4H98 A;  5HQZ A;  2O7P A;  6DFR A;  2INQ A;  3NZB X;  1HFQ A;  1LY4 A;  3HJ3 A;  3TQ8 A;  2BLA A;  2JYB A;  3JWM A;  4G8Z X;  3NZA X;  1PD9 A;  2QK8 A;  3OCH A;  1RE7 A;  2C2S A;  3KJR A;  1DHF A;  3UM5 A;  4QI9 A;  4LAH X;  4KAK A;  3DGA A;  2BL9 A;  1J3K A;  4DDR A;  3LG4 A;  1S3V A;  1U70 A;  3SR5 X;  1DR2 A;  3GHW A;  3D80 A;  5JG0 X;  4KFJ A;  3S9U A;  1DYH A;  3NZC X;  3E0B A;  1DG5 A;  2ANO A;  1S3W A;  2W9S A;  3NZD A;  1DYI A;  4ECK A;  3TD8 A;  4QLE A;  3RG9 A;  1AOE A;  5ECX A;  1JOL A;  3QLR A;  3GI2 A;  1RG7 A;  3NXV A;  3R33 A;  1DLR A;  2ZZA A;  3IRM A;  3FQC A;  4ELE A;  1JOM A;  3NXT A;  1RA8 A;  4ELB A;  4X5J A;  4X5I A;  2LF1 A;  1YHO A;  1RB3 A;  3CSE A;  4P3R A;  1HFP A;  4G95 A;  2XW7 A;  1S3U A;  3FYV X;  4H95 A;  3QLW A;  2OIP A;  3DAU A;  1DHI A;  4X5H A;  1RX1 A;  5HVB A;  1KMV A;  4G3M A;  4DFR A;  5DFR A;  4KD7 A;  4RGC A;  3GHC A;  3GYF A;  1RD7 A;  2DRC A;  3CL9 A;  8DFR A;  1RC4 A;  1RX2 A;  4KY4 A;  4XT4 A;  3F8Y A;  5HI6 A;  1JUV A;  2D5N A;  3DRC A;  3SH2 A;  4XT6 A;  4P3Q A;  4OR7 A;  1D1G A;  3NZ6 X;  4KNE A;  1M7A A;  1IA2 A;  4Q0D A;  1DR5 A;  2HM9 A;  4FHB A;  2P4G A;  1DF7 A;  3QL0 A;  4IXG X;  3DG8 A;  2AZN A;  4Q0E A;  3KGY A;  3FRF X;  1VDR A;  5CCC A;  5JA3 A;  1LUD A;  2W3M A;  2W9H A;  3NU0 A;  3F0B X;  2BLB A;  5HQY A;  1RH3 A;  5U26 A;  5FDA A;  4QHV A;  3JWC A;  4QJC A;  2KGK A;  5DXV A;  5HT4 A;  2GD9 A;  3I3R A;  4FGG A;  1RA9 A;  5HSU A;  3N0H A;  1DRE A;  4ELF A;  3M08 A;  3DFR A;  3JW5 A;  4QJZ D;  4HA9 A;  3TQB A;  4M6L A;  3QLY A;  3QYL A;  2ITH A;  3QG2 A;  3NXO A;  1AI9 A;  5HSR A;  3I8A X;  3QLS A;  3S3V A;  4FGH A;  3QGT A;  3SRS X;  3NRR A;  4XT8 A;  3KFY A;  1DRA A;  3K74 A;  3TQ9 A;  7DFR A;  3FS6 A;  3ZPG A;  4HOF A;  4M6K A;  5ECC A;  3SRQ X;  3F8Z A;  4H97 A;  3F0V X;  1E26 A;  1PD8 A;  3SQY X;  2W9G A;  3HBB A;  3UM6 A;  4XT5 A;  3JW3 A;  1DYJ A;  1J3J A;  1J3I A;  5HPB A;  4KY8 A;  4PTJ A;  3IA4 A;  1BZF A;  3QLZ A;  2CD2 A;  3SA1 A;  1S3Y A;  3SRR X;  4M7U A;  4EJ1 A;  1DHJ A;  3JSU A;  3FQO A;  1OHK A;  3NXX A;  3SGY A;  3SA2 A;  3K45 A;  3QLX A;  4HOE A;  3FQZ A;  4XE6 X;  1RX5 A;  4KM2 A;  1PDB A;  3CD2 A;  5HVE A;  4PSY A;  2FZH A;  4KJJ A;  1DDS A;  4I1N A;  4KJL A;  3F91 A;  3QYO A;  2FZI A;  4X5F A;  4HA7 A;  1RX6 A;  4NX7 A;  4KEB A;  2W3A A;  3FRB X;  3FL9 A;  1IA4 A;  3IRN A;  4KJK A;  4HOG A;  3EIG A;  2W3B A;  1M78 A;  4M6J A;  4PDJ A;  3KY8 A;  3CLB A;  4QLG A;  1RX8 A;  1DR4 A;  3K47 A;  1CD2 A;  3Q1H A;  4EIG A;  3FRA X;  1HFR A;  4CD2 A;  1OHJ A;  4M2X A;  1BOZ A;  3EEM A;  4ELG A;  3QFX A;  4Q6A A;  3FL8 A;  3GHV A;  2G6V A;  5CC9 A;  4QLF A;  2W9T A;  1RX7 A;  3IRO A;  3FRD X;  2ANQ A;  4M7V A;  1AO8 A;  1ZDR A;  2C2T A;  3DAT A;  1DR3 A;  2B3Z A;  4P66 A;  1DRF A;  3JVX A;  3FY9 X;  1VJ3 A;  4EIL A;  3NZ9 X;  3F0U X;  4XRB A;  3JWF A;  3M09 A;  4DPD A;  4LEK X;  4KL9 A;  2HXV A;  1U71 A;  4IXE D;  3NTZ A;  4X5G A;  1MVT A;  1DDR A;  1IA1 A;  5HT5 A;  3FQ0 A;  4KYA A;  4GH8 A;  1U72 A;  1DAJ A;  3K2H A;  4Q67 A;  1DIS A;  4KBN A;  4LAG X;  3SAI A;  4XT7 A;  3IA5 A;  4PTH A;  4PST A;  4PSS A;  1M79 A;  3F0S X;  1DIU A;  2H2Q A;  1RB2 A;  1DR6 A;  3D84 X;  2HQP A;  1DLS A;  5E8Q A;  3JTW A;  2FZJ A;  3L3R A;  1TDR A;  1DG8 A;  1QZF A;  4KM0 A;  3QL3 A;  3SRW X;  4DP3 A;  4H96 A;  2CIG A;  3DL5 A;  2OBC A; 
#chains in the Genus database with same CATH topology
 3NXR A;  3OAF A;  4DPH A;  1DR1 A;  3F0Q X;  3FRE X;  3FQV A;  3ROA A;  1CZ3 A;  3RO9 A;  4I13 A;  1DRH A;  3F0X X;  1RX9 A;  1RA1 A;  4TU5 X;  1RA2 A;  4ELH A;  5HF2 X;  3KJS A;  1IA3 A;  3VCO A;  1RX4 A;  4LAE X;  3EEJ A;  4EIZ A;  3EEL A;  3INV A;  4KLX A;  4IXF X;  4NX6 A;  1DYR A;  1RA3 A;  1LY3 A;  1RF7 A;  5U27 A;  5HF0 X;  3IX9 A;  2D0K A;  2BLC A;  5HUI A;  3FQF A;  3UM8 A;  1DG7 A;  3TQA A;  1SEJ A;  2W3V A;  3JWK A;  3FY8 X;  1RX3 A;  3S7A A;  3EEK A;  2DHF A;  1KMS A;  5EAJ A;  1MVS A;  1DRB A;  3FYW X;  3DL6 A;  4P68 A;  4XEC X;  2W3W A;  3EX8 A;  1KLK A;  3ZPC A;  4OSG A;  3SRU X;  1DR7 A;  2L28 A;  3NXY A;  4H98 A;  5HQZ A;  2O7P A;  6DFR A;  2INQ A;  3NZB X;  1HFQ A;  1LY4 A;  3HJ3 A;  3TQ8 A;  2BLA A;  2JYB A;  3JWM A;  4G8Z X;  3NZA X;  1PD9 A;  2QK8 A;  3OCH A;  1RE7 A;  2C2S A;  3KJR A;  1DHF A;  3UM5 A;  4QI9 A;  4LAH X;  4KAK A;  3DGA A;  2BL9 A;  1J3K A;  4DDR A;  3LG4 A;  1S3V A;  1U70 A;  3SR5 X;  1DR2 A;  3GHW A;  3D80 A;  5JG0 X;  4KFJ A;  3S9U A;  1DYH A;  3NZC X;  3E0B A;  1DG5 A;  2ANO A;  1S3W A;  2W9S A;  3NZD A;  1DYI A;  4ECK A;  3TD8 A;  4QLE A;  3RG9 A;  1AOE A;  5ECX A;  1JOL A;  3QLR A;  3GI2 A;  1RG7 A;  3NXV A;  3R33 A;  1DLR A;  2ZZA A;  3IRM A;  3FQC A;  4ELE A;  1JOM A;  3NXT A;  1RA8 A;  4ELB A;  4X5J A;  4X5I A;  2LF1 A;  1YHO A;  1RB3 A;  3CSE A;  4P3R A;  1HFP A;  4G95 A;  2XW7 A;  1S3U A;  3FYV X;  4H95 A;  3QLW A;  2OIP A;  3DAU A;  1DHI A;  4X5H A;  1RX1 A;  5HVB A;  1KMV A;  4G3M A;  4DFR A;  5DFR A;  4KD7 A;  4RGC A;  3GHC A;  3GYF A;  1RD7 A;  2DRC A;  3CL9 A;  8DFR A;  1RC4 A;  1RX2 A;  4KY4 A;  4XT4 A;  3F8Y A;  5HI6 A;  1JUV A;  2D5N A;  3DRC A;  3SH2 A;  4XT6 A;  4P3Q A;  4OR7 A;  1D1G A;  3NZ6 X;  4KNE A;  1M7A A;  1IA2 A;  4Q0D A;  1DR5 A;  2HM9 A;  4FHB A;  2P4G A;  1DF7 A;  3QL0 A;  4IXG X;  3DG8 A;  2AZN A;  4Q0E A;  3KGY A;  3FRF X;  1VDR A;  5CCC A;  5JA3 A;  1LUD A;  2W3M A;  2W9H A;  3NU0 A;  3F0B X;  2BLB A;  5HQY A;  1RH3 A;  5U26 A;  5FDA A;  4QHV A;  3JWC A;  4QJC A;  2KGK A;  5DXV A;  5HT4 A;  2GD9 A;  3I3R A;  4FGG A;  1RA9 A;  5HSU A;  3N0H A;  1DRE A;  4ELF A;  3M08 A;  3DFR A;  3JW5 A;  4QJZ D;  4HA9 A;  3TQB A;  4M6L A;  3QLY A;  3QYL A;  2ITH A;  3QG2 A;  3NXO A;  1AI9 A;  5HSR A;  3I8A X;  3QLS A;  3S3V A;  4FGH A;  3QGT A;  3SRS X;  3NRR A;  4XT8 A;  3KFY A;  1DRA A;  3K74 A;  3TQ9 A;  7DFR A;  3FS6 A;  3ZPG A;  4HOF A;  4M6K A;  5ECC A;  3SRQ X;  3F8Z A;  4H97 A;  3F0V X;  1E26 A;  1PD8 A;  3SQY X;  2W9G A;  3HBB A;  3UM6 A;  4XT5 A;  3JW3 A;  1DYJ A;  1J3J A;  1J3I A;  5HPB A;  4KY8 A;  4PTJ A;  3IA4 A;  1BZF A;  3QLZ A;  2CD2 A;  3SA1 A;  1S3Y A;  3SRR X;  4M7U A;  4EJ1 A;  1DHJ A;  3JSU A;  3FQO A;  1OHK A;  3NXX A;  3SGY A;  3SA2 A;  3K45 A;  3QLX A;  4HOE A;  3FQZ A;  4XE6 X;  1RX5 A;  4KM2 A;  1PDB A;  3CD2 A;  5HVE A;  4PSY A;  2FZH A;  4KJJ A;  1DDS A;  4I1N A;  4KJL A;  3F91 A;  3QYO A;  2FZI A;  4X5F A;  4HA7 A;  1RX6 A;  4NX7 A;  4KEB A;  2W3A A;  3FRB X;  3FL9 A;  1IA4 A;  3IRN A;  4KJK A;  4HOG A;  3EIG A;  2W3B A;  1M78 A;  4M6J A;  4PDJ A;  3KY8 A;  3CLB A;  4QLG A;  1RX8 A;  1DR4 A;  3K47 A;  1CD2 A;  3Q1H A;  4EIG A;  3FRA X;  1HFR A;  4CD2 A;  1OHJ A;  4M2X A;  1BOZ A;  3EEM A;  4ELG A;  3QFX A;  4Q6A A;  3FL8 A;  3GHV A;  2G6V A;  5CC9 A;  4QLF A;  2W9T A;  1RX7 A;  3IRO A;  3FRD X;  2ANQ A;  4M7V A;  1AO8 A;  1ZDR A;  2C2T A;  3DAT A;  1DR3 A;  2B3Z A;  4P66 A;  1DRF A;  3JVX A;  3FY9 X;  1VJ3 A;  4EIL A;  3NZ9 X;  3F0U X;  4XRB A;  3JWF A;  3M09 A;  4DPD A;  4LEK X;  4KL9 A;  2HXV A;  1U71 A;  4IXE D;  3NTZ A;  4X5G A;  1MVT A;  1DDR A;  1IA1 A;  5HT5 A;  3FQ0 A;  4KYA A;  4GH8 A;  1U72 A;  1DAJ A;  3K2H A;  4Q67 A;  1DIS A;  4KBN A;  4LAG X;  3SAI A;  4XT7 A;  3IA5 A;  4PTH A;  4PST A;  4PSS A;  1M79 A;  3F0S X;  1DIU A;  2H2Q A;  1RB2 A;  1DR6 A;  3D84 X;  2HQP A;  1DLS A;  5E8Q A;  3JTW A;  2FZJ A;  3L3R A;  1TDR A;  1DG8 A;  1QZF A;  4KM0 A;  3QL3 A;  3SRW X;  4DP3 A;  4H96 A;  2CIG A;  3DL5 A;  2OBC A; 
#chains in the Genus database with same CATH homology
 3NXR A;  3OAF A;  4DPH A;  1DR1 A;  3F0Q X;  3FRE X;  3FQV A;  3ROA A;  1CZ3 A;  3RO9 A;  4I13 A;  1DRH A;  3F0X X;  1RX9 A;  1RA1 A;  4TU5 X;  1RA2 A;  4ELH A;  5HF2 X;  3KJS A;  1IA3 A;  3VCO A;  1RX4 A;  4LAE X;  3EEJ A;  4EIZ A;  3EEL A;  3INV A;  4KLX A;  4IXF X;  4NX6 A;  1DYR A;  1RA3 A;  1LY3 A;  1RF7 A;  5U27 A;  5HF0 X;  3IX9 A;  2D0K A;  2BLC A;  5HUI A;  3FQF A;  3UM8 A;  1DG7 A;  3TQA A;  1SEJ A;  2W3V A;  3JWK A;  3FY8 X;  1RX3 A;  3S7A A;  3EEK A;  2DHF A;  1KMS A;  5EAJ A;  1MVS A;  1DRB A;  3FYW X;  3DL6 A;  4P68 A;  4XEC X;  2W3W A;  3EX8 A;  1KLK A;  3ZPC A;  4OSG A;  3SRU X;  1DR7 A;  2L28 A;  3NXY A;  4H98 A;  5HQZ A;  2O7P A;  6DFR A;  2INQ A;  3NZB X;  1HFQ A;  1LY4 A;  3HJ3 A;  3TQ8 A;  2BLA A;  2JYB A;  3JWM A;  4G8Z X;  3NZA X;  1PD9 A;  2QK8 A;  3OCH A;  1RE7 A;  2C2S A;  3KJR A;  1DHF A;  3UM5 A;  4QI9 A;  4LAH X;  4KAK A;  3DGA A;  2BL9 A;  1J3K A;  4DDR A;  3LG4 A;  1S3V A;  1U70 A;  3SR5 X;  1DR2 A;  3GHW A;  3D80 A;  5JG0 X;  4KFJ A;  3S9U A;  1DYH A;  3NZC X;  3E0B A;  1DG5 A;  2ANO A;  1S3W A;  2W9S A;  3NZD A;  1DYI A;  4ECK A;  3TD8 A;  4QLE A;  3RG9 A;  1AOE A;  5ECX A;  1JOL A;  3QLR A;  3GI2 A;  1RG7 A;  3NXV A;  3R33 A;  1DLR A;  2ZZA A;  3IRM A;  3FQC A;  4ELE A;  1JOM A;  3NXT A;  1RA8 A;  4ELB A;  4X5J A;  4X5I A;  2LF1 A;  1YHO A;  1RB3 A;  3CSE A;  4P3R A;  1HFP A;  4G95 A;  2XW7 A;  1S3U A;  3FYV X;  4H95 A;  3QLW A;  2OIP A;  3DAU A;  1DHI A;  4X5H A;  1RX1 A;  5HVB A;  1KMV A;  4G3M A;  4DFR A;  5DFR A;  4KD7 A;  4RGC A;  3GHC A;  3GYF A;  1RD7 A;  2DRC A;  3CL9 A;  8DFR A;  1RC4 A;  1RX2 A;  4KY4 A;  4XT4 A;  3F8Y A;  5HI6 A;  1JUV A;  2D5N A;  3DRC A;  3SH2 A;  4XT6 A;  4P3Q A;  4OR7 A;  1D1G A;  3NZ6 X;  4KNE A;  1M7A A;  1IA2 A;  4Q0D A;  1DR5 A;  2HM9 A;  4FHB A;  2P4G A;  1DF7 A;  3QL0 A;  4IXG X;  3DG8 A;  2AZN A;  4Q0E A;  3KGY A;  3FRF X;  1VDR A;  5CCC A;  5JA3 A;  1LUD A;  2W3M A;  2W9H A;  3NU0 A;  3F0B X;  2BLB A;  5HQY A;  1RH3 A;  5U26 A;  5FDA A;  4QHV A;  3JWC A;  4QJC A;  2KGK A;  5DXV A;  5HT4 A;  2GD9 A;  3I3R A;  4FGG A;  1RA9 A;  5HSU A;  3N0H A;  1DRE A;  4ELF A;  3M08 A;  3DFR A;  3JW5 A;  4QJZ D;  4HA9 A;  3TQB A;  4M6L A;  3QLY A;  3QYL A;  2ITH A;  3QG2 A;  3NXO A;  1AI9 A;  5HSR A;  3I8A X;  3QLS A;  3S3V A;  4FGH A;  3QGT A;  3SRS X;  3NRR A;  4XT8 A;  3KFY A;  1DRA A;  3K74 A;  3TQ9 A;  7DFR A;  3FS6 A;  3ZPG A;  4HOF A;  4M6K A;  5ECC A;  3SRQ X;  3F8Z A;  4H97 A;  3F0V X;  1E26 A;  1PD8 A;  3SQY X;  2W9G A;  3HBB A;  3UM6 A;  4XT5 A;  3JW3 A;  1DYJ A;  1J3J A;  1J3I A;  5HPB A;  4KY8 A;  4PTJ A;  3IA4 A;  1BZF A;  3QLZ A;  2CD2 A;  3SA1 A;  1S3Y A;  3SRR X;  4M7U A;  4EJ1 A;  1DHJ A;  3JSU A;  3FQO A;  1OHK A;  3NXX A;  3SGY A;  3SA2 A;  3K45 A;  3QLX A;  4HOE A;  3FQZ A;  4XE6 X;  1RX5 A;  4KM2 A;  1PDB A;  3CD2 A;  5HVE A;  4PSY A;  2FZH A;  4KJJ A;  1DDS A;  4I1N A;  4KJL A;  3F91 A;  3QYO A;  2FZI A;  4X5F A;  4HA7 A;  1RX6 A;  4NX7 A;  4KEB A;  2W3A A;  3FRB X;  3FL9 A;  1IA4 A;  3IRN A;  4KJK A;  4HOG A;  3EIG A;  2W3B A;  1M78 A;  4M6J A;  4PDJ A;  3KY8 A;  3CLB A;  4QLG A;  1RX8 A;  1DR4 A;  3K47 A;  1CD2 A;  3Q1H A;  4EIG A;  3FRA X;  1HFR A;  4CD2 A;  1OHJ A;  4M2X A;  1BOZ A;  3EEM A;  4ELG A;  3QFX A;  4Q6A A;  3FL8 A;  3GHV A;  2G6V A;  5CC9 A;  4QLF A;  2W9T A;  1RX7 A;  3IRO A;  3FRD X;  2ANQ A;  4M7V A;  1AO8 A;  1ZDR A;  2C2T A;  3DAT A;  1DR3 A;  2B3Z A;  4P66 A;  1DRF A;  3JVX A;  3FY9 X;  1VJ3 A;  4EIL A;  3NZ9 X;  3F0U X;  4XRB A;  3JWF A;  3M09 A;  4DPD A;  4LEK X;  4KL9 A;  2HXV A;  1U71 A;  4IXE D;  3NTZ A;  4X5G A;  1MVT A;  1DDR A;  1IA1 A;  5HT5 A;  3FQ0 A;  4KYA A;  4GH8 A;  1U72 A;  1DAJ A;  3K2H A;  4Q67 A;  1DIS A;  4KBN A;  4LAG X;  3SAI A;  4XT7 A;  3IA5 A;  4PTH A;  4PST A;  4PSS A;  1M79 A;  3F0S X;  1DIU A;  2H2Q A;  1RB2 A;  1DR6 A;  3D84 X;  2HQP A;  1DLS A;  5E8Q A;  3JTW A;  2FZJ A;  3L3R A;  1TDR A;  1DG8 A;  1QZF A;  4KM0 A;  3QL3 A;  3SRW X;  4DP3 A;  4H96 A;  2CIG A;  3DL5 A;  2OBC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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