3NZAX

Structural analysis of pneumocystis carinii and human dhfr complexes with nadph and a series of five potent 5-(omega-carboxy(alkyloxy)pyrido[2,3-d]pyrimidine derivatives
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
206
structure length
206
Chain Sequence
MNQQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQFRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-([omega]-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Pneumocystis carinii
molecule keywords Dihydrofolate reductase
total genus 59
structure length 206
sequence length 206
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3nzaX00
1KMVA 1RD7A 1HFRA 3QG2A 4FHBA 2ZZAA 3OAFA 1RH3A 1RA2A 4G8ZX 3NXVA 1AI9A 4Q67A 3Q1HA 3JWFA 1VDRA 1S3UA 4KJLA 4OSGA 1CZ3A 3D84X 1RX2A 5HF2X 2G6VA 3UM8A 3FYVX 3F8ZA 3NXOA 1IA3A 3FQOA 3JSUA 3D80A 1LUDA 1TDRA 4DDRA 4ELGA 4EIGA 1DG7A 3F0BX 2W9TA 3NZ9X 3JW3A 3DGAA 3FQ0A 2DHFA 2BL9A 3EELA 1DR4A 3NXXA 3SRQX 2W9SA 1ZDRA 5CCCA 3R33A 3FY8X 2O7PA 3INVA 1VJ3A 2H2QA 4PTJA 4QHVA 3EX8A 7DFRA 1IA2A 4HOEA 2ANQA 5HI6A 1DHIA 1DHJA 2W3WA 4XT7A 3DRCA 3GHWA 3JVXA 5HT5A 1DYRA 3CLBA 1DR6A 1DRBA 4M7UA 3JW5A 3QLYA 1DYIA 1MVSA 2LF1A 3TD8A 4IXGX 4QJCA 3F0SX 4KBNA 3QLSA 3FRDX 3LG4A 3IRMA 1PDBA 1RB3A 1U71A 4RGCA 4IXFX 1MVTA 3UM6A 3SGYA 4KYAA 1RE7A 4LEKX 1HFPA 2W3VA 5HSUA 4EILA 1JOLA 3RO9A 4M6JA 1DIUA 3K74A 3FRBX 4PSSA 3QLXA 3IROA 4PDJA 3NRRA 1PD8A 3S3VA 3QLRA 4DPHA 2OIPA 4KJJA 4QLFA 5HPBA 4QLGA 2AZNA 3QYOA 3GYFA 3NZ6X 4ECKA 1BZFA 3F8YA 2QK8A 5HQZA 3JWKA 5EAJA 3KJRA 5DXVA 1RX8A 3EEJA 1RX1A 1CD2A 1DR3A 1S3YA 1PD9A 1BOZA 3TQBA 1RX7A 3I8AX 3RG9A 3JTWA 4KFJA 1DDRA 1JOMA 2XW7A 1OHKA 1RF7A 4KD7A 4P3RA 4P66A 4OR7A 2BLAA 2OBCA 2W3MA 4M6KA 4PSTA 4KNEA 1RX5A 3SR5X 3TQ9A 3SRSX 3E0BA 3ROAA 1IA4A 3SA2A 5DFRA 3KGYA 3CSEA 2HM9A 3K2HA 2JYBA 1RX3A 2HXVA 2W9GA 3SH2A 1RB2A 4NX7A 2CIGA 3KFYA 2BLBA 4Q0EA 1RX6A 3DL5A 4I13A 4M2XA 2KGKA 3S7AA 3IX9A 4ELHA 1M7AA 1HFQA 4DPDA 1DRHA 4G95A 3SRWX 1DYJA 5FDAA 1DF7A 1RA9A 1AOEA 1DDSA 1RX4A 4XT4A 3SRUX 2FZIA 3K45A 4LAEX 3EIGA 4X5JA 2BLCA 1KLKA 4QI9A 5CC9A 2GD9A 5HT4A 1J3KA 1J3JA 4XRBA 3FY9X 4ELBA 3F0XX 1DR1A 3M09A 4KL9A 3F91A 4X5FA 3JWMA 4QLEA 3ZPGA 1IA1A 3NTZA 5HSRA 3FQVA 3FQCA 4X5IA 1DR2A 1RA3A 1DREA 4P68A 2C2TA 3KY8A 1JUVA 4EIZA 3DL6A 3NXRA 1OHJA 3FQZA 3F0VX 3QFXA 3I3RA 5JA3A 1S3VA 4QJZD 1RC4A 3F0UX 2W9HA 5HVBA 3F0QX 4M6LA 1M78A 2ANOA 2P4GA 4KAKA 4XECX 3CL9A 2DRCA 4EJ1A 3NZDA 3IA4A 3QL3A 3DATA 3DFRA 4DP3A 3SA1A 3KJSA 3FS6A 1QZFA 5HQYA 4X5HA 2CD2A 1DISA 4I1NA 4H95A 3GHVA 2FZHA 4HA9A 1RG7A 4P3QA 2HQPA 3GI2A 4KLXA 4KEBA 3K47A 3OCHA 4PSYA 4XT8A 4H97A 4XE6X 3FRAX 1U72A 8DFRA 1DLSA 4X5GA 1DR7A 3FQFA 4KM0A 3NZAX 1RX9A 1S3WA 4ELEA 3VCOA 3QLWA 5ECCA 4ELFA 4Q6AA 3EEKA 2ITHA 5E8QA 1DG8A 4FGHA 4KM2A 1RA1A 2FZJA 3ZPCA 4LAHX 5U26A 4NX6A 1DLRA 4CD2A 1RA8A 4HOGA 2D5NA 1DAJA 1DHFA 2D0KA 3DAUA 3QGTA 3NZCX 3QYLA 5ECXA 1LY3A 4XT6A 3HJ3A 2W3AA 4TU5X 4HOFA 3CD2A 2L28A 3SAIA 4FGGA 5JG0X 1KMSA 4H98A 3IA5A 3QLZA 4GH8A 5HVEA 1J3IA 2B3ZA 3NZBX 1U70A 2INQA 3GHCA 3FYWX 3S9UA 1SEJA 3FRFX 3NXTA 1DRAA 3EEMA 2W3BA 3N0HA 6DFRA 3FL9A 3IRNA 3FL8A 3JWCA 4XT5A 4KY4A 4H96A 1E26A 4KJKA 1DG5A 3SQYX 3HBBA 1DR5A 3TQAA 1D1GA 4G3MA 4DFRA 4Q0DA 1M79A 4IXED 3TQ8A 5HF0X 4M7VA 3L3RA 1DRFA 4PTHA 3UM5A 3QL0A 1DYHA 3M08A 4LAGX 3SRRX 1AO8A 4HA7A 2C2SA 3FREX 5U27A 3NXYA 5HUIA 3DG8A 1LY4A 3NU0A 4KY8A 1YHOA
chains in the Genus database with same CATH superfamily
1KMVA 1RD7A 1HFRA 3QG2A 4FHBA 2ZZAA 3OAFA 1RH3A 1RA2A 4G8ZX 3NXVA 1AI9A 4Q67A 3Q1HA 3JWFA 1VDRA 1S3UA 4KJLA 4OSGA 1CZ3A 3D84X 1RX2A 5HF2X 2G6VA 3UM8A 3FYVX 3F8ZA 3NXOA 1IA3A 3FQOA 3JSUA 3D80A 1LUDA 1TDRA 4DDRA 4ELGA 4EIGA 1DG7A 3F0BX 2W9TA 3NZ9X 3JW3A 3DGAA 3FQ0A 2DHFA 2BL9A 3EELA 1DR4A 3NXXA 3SRQX 2W9SA 1ZDRA 5CCCA 3R33A 3FY8X 2O7PA 3INVA 1VJ3A 2H2QA 4PTJA 4QHVA 3EX8A 7DFRA 1IA2A 4HOEA 2ANQA 5HI6A 1DHIA 1DHJA 2W3WA 4XT7A 3DRCA 3GHWA 3JVXA 5HT5A 1DYRA 3CLBA 1DR6A 1DRBA 4M7UA 3JW5A 3QLYA 1DYIA 1MVSA 2LF1A 3TD8A 4IXGX 4QJCA 3F0SX 4KBNA 3QLSA 3FRDX 3LG4A 3IRMA 1PDBA 1RB3A 1U71A 4RGCA 4IXFX 1MVTA 3UM6A 3SGYA 4KYAA 1RE7A 4LEKX 1HFPA 2W3VA 5HSUA 4EILA 1JOLA 3RO9A 4M6JA 1DIUA 3K74A 3FRBX 4PSSA 3QLXA 3IROA 4PDJA 3NRRA 1PD8A 3S3VA 3QLRA 4DPHA 2OIPA 4KJJA 4QLFA 5HPBA 4QLGA 2AZNA 3QYOA 3GYFA 3NZ6X 4ECKA 1BZFA 3F8YA 2QK8A 5HQZA 3JWKA 5EAJA 3KJRA 5DXVA 1RX8A 3EEJA 1RX1A 1CD2A 1DR3A 1S3YA 1PD9A 1BOZA 3TQBA 1RX7A 3I8AX 3RG9A 3JTWA 4KFJA 1DDRA 1JOMA 2XW7A 1OHKA 1RF7A 4KD7A 4P3RA 4P66A 4OR7A 2BLAA 2OBCA 2W3MA 4M6KA 4PSTA 4KNEA 1RX5A 3SR5X 3TQ9A 3SRSX 3E0BA 3ROAA 1IA4A 3SA2A 5DFRA 3KGYA 3CSEA 2HM9A 3K2HA 2JYBA 1RX3A 2HXVA 2W9GA 3SH2A 1RB2A 4NX7A 2CIGA 3KFYA 2BLBA 4Q0EA 1RX6A 3DL5A 4I13A 4M2XA 2KGKA 3S7AA 3IX9A 4ELHA 1M7AA 1HFQA 4DPDA 1DRHA 4G95A 3SRWX 1DYJA 5FDAA 1DF7A 1RA9A 1AOEA 1DDSA 1RX4A 4XT4A 3SRUX 2FZIA 3K45A 4LAEX 3EIGA 4X5JA 2BLCA 1KLKA 4QI9A 5CC9A 2GD9A 5HT4A 1J3KA 1J3JA 4XRBA 3FY9X 4ELBA 3F0XX 1DR1A 3M09A 4KL9A 3F91A 4X5FA 3JWMA 4QLEA 3ZPGA 1IA1A 3NTZA 5HSRA 3FQVA 3FQCA 4X5IA 1DR2A 1RA3A 1DREA 4P68A 2C2TA 3KY8A 1JUVA 4EIZA 3DL6A 3NXRA 1OHJA 3FQZA 3F0VX 3QFXA 3I3RA 5JA3A 1S3VA 4QJZD 1RC4A 3F0UX 2W9HA 5HVBA 3F0QX 4M6LA 1M78A 2ANOA 2P4GA 4KAKA 4XECX 3CL9A 2DRCA 4EJ1A 3NZDA 3IA4A 3QL3A 3DATA 3DFRA 4DP3A 3SA1A 3KJSA 3FS6A 1QZFA 5HQYA 4X5HA 2CD2A 1DISA 4I1NA 4H95A 3GHVA 2FZHA 4HA9A 1RG7A 4P3QA 2HQPA 3GI2A 4KLXA 4KEBA 3K47A 3OCHA 4PSYA 4XT8A 4H97A 4XE6X 3FRAX 1U72A 8DFRA 1DLSA 4X5GA 1DR7A 3FQFA 4KM0A 3NZAX 1RX9A 1S3WA 4ELEA 3VCOA 3QLWA 5ECCA 4ELFA 4Q6AA 3EEKA 2ITHA 5E8QA 1DG8A 4FGHA 4KM2A 1RA1A 2FZJA 3ZPCA 4LAHX 5U26A 4NX6A 1DLRA 4CD2A 1RA8A 4HOGA 2D5NA 1DAJA 1DHFA 2D0KA 3DAUA 3QGTA 3NZCX 3QYLA 5ECXA 1LY3A 4XT6A 3HJ3A 2W3AA 4TU5X 4HOFA 3CD2A 2L28A 3SAIA 4FGGA 5JG0X 1KMSA 4H98A 3IA5A 3QLZA 4GH8A 5HVEA 1J3IA 2B3ZA 3NZBX 1U70A 2INQA 3GHCA 3FYWX 3S9UA 1SEJA 3FRFX 3NXTA 1DRAA 3EEMA 2W3BA 3N0HA 6DFRA 3FL9A 3IRNA 3FL8A 3JWCA 4XT5A 4KY4A 4H96A 1E26A 4KJKA 1DG5A 3SQYX 3HBBA 1DR5A 3TQAA 1D1GA 4G3MA 4DFRA 4Q0DA 1M79A 4IXED 3TQ8A 5HF0X 4M7VA 3L3RA 1DRFA 4PTHA 3UM5A 3QL0A 1DYHA 3M08A 4LAGX 3SRRX 1AO8A 4HA7A 2C2SA 3FREX 5U27A 3NXYA 5HUIA 3DG8A 1LY4A 3NU0A 4KY8A 1YHOA
chains in the Genus database with same CATH topology
1KMVA 1RD7A 1HFRA 3QG2A 4FHBA 2ZZAA 3OAFA 1RH3A 1RA2A 4G8ZX 3NXVA 1AI9A 4Q67A 3Q1HA 3JWFA 1VDRA 1S3UA 4KJLA 4OSGA 1CZ3A 3D84X 1RX2A 5HF2X 2G6VA 3UM8A 3FYVX 3F8ZA 3NXOA 1IA3A 3FQOA 3JSUA 3D80A 1LUDA 1TDRA 4DDRA 4ELGA 4EIGA 1DG7A 3F0BX 2W9TA 3NZ9X 3JW3A 3DGAA 3FQ0A 2DHFA 2BL9A 3EELA 1DR4A 3NXXA 3SRQX 2W9SA 1ZDRA 5CCCA 3R33A 3FY8X 2O7PA 3INVA 1VJ3A 2H2QA 4PTJA 4QHVA 3EX8A 7DFRA 1IA2A 4HOEA 2ANQA 5HI6A 1DHIA 1DHJA 2W3WA 4XT7A 3DRCA 3GHWA 3JVXA 5HT5A 1DYRA 3CLBA 1DR6A 1DRBA 4M7UA 3JW5A 3QLYA 1DYIA 1MVSA 2LF1A 3TD8A 4IXGX 4QJCA 3F0SX 4KBNA 3QLSA 3FRDX 3LG4A 3IRMA 1PDBA 1RB3A 1U71A 4RGCA 4IXFX 1MVTA 3UM6A 3SGYA 4KYAA 1RE7A 4LEKX 1HFPA 2W3VA 5HSUA 4EILA 1JOLA 3RO9A 4M6JA 1DIUA 3K74A 3FRBX 4PSSA 3QLXA 3IROA 4PDJA 3NRRA 1PD8A 3S3VA 3QLRA 4DPHA 2OIPA 4KJJA 4QLFA 5HPBA 4QLGA 2AZNA 3QYOA 3GYFA 3NZ6X 4ECKA 1BZFA 3F8YA 2QK8A 5HQZA 3JWKA 5EAJA 3KJRA 5DXVA 1RX8A 3EEJA 1RX1A 1CD2A 1DR3A 1S3YA 1PD9A 1BOZA 3TQBA 1RX7A 3I8AX 3RG9A 3JTWA 4KFJA 1DDRA 1JOMA 2XW7A 1OHKA 1RF7A 4KD7A 4P3RA 4P66A 4OR7A 2BLAA 2OBCA 2W3MA 4M6KA 4PSTA 4KNEA 1RX5A 3SR5X 3TQ9A 3SRSX 3E0BA 3ROAA 1IA4A 3SA2A 5DFRA 3KGYA 3CSEA 2HM9A 3K2HA 2JYBA 1RX3A 2HXVA 2W9GA 3SH2A 1RB2A 4NX7A 2CIGA 3KFYA 2BLBA 4Q0EA 1RX6A 3DL5A 4I13A 4M2XA 2KGKA 3S7AA 3IX9A 4ELHA 1M7AA 1HFQA 4DPDA 1DRHA 4G95A 3SRWX 1DYJA 5FDAA 1DF7A 1RA9A 1AOEA 1DDSA 1RX4A 4XT4A 3SRUX 2FZIA 3K45A 4LAEX 3EIGA 4X5JA 2BLCA 1KLKA 4QI9A 5CC9A 2GD9A 5HT4A 1J3KA 1J3JA 4XRBA 3FY9X 4ELBA 3F0XX 1DR1A 3M09A 4KL9A 3F91A 4X5FA 3JWMA 4QLEA 3ZPGA 1IA1A 3NTZA 5HSRA 3FQVA 3FQCA 4X5IA 1DR2A 1RA3A 1DREA 4P68A 2C2TA 3KY8A 1JUVA 4EIZA 3DL6A 3NXRA 1OHJA 3FQZA 3F0VX 3QFXA 3I3RA 5JA3A 1S3VA 4QJZD 1RC4A 3F0UX 2W9HA 5HVBA 3F0QX 4M6LA 1M78A 2ANOA 2P4GA 4KAKA 4XECX 3CL9A 2DRCA 4EJ1A 3NZDA 3IA4A 3QL3A 3DATA 3DFRA 4DP3A 3SA1A 3KJSA 3FS6A 1QZFA 5HQYA 4X5HA 2CD2A 1DISA 4I1NA 4H95A 3GHVA 2FZHA 4HA9A 1RG7A 4P3QA 2HQPA 3GI2A 4KLXA 4KEBA 3K47A 3OCHA 4PSYA 4XT8A 4H97A 4XE6X 3FRAX 1U72A 8DFRA 1DLSA 4X5GA 1DR7A 3FQFA 4KM0A 3NZAX 1RX9A 1S3WA 4ELEA 3VCOA 3QLWA 5ECCA 4ELFA 4Q6AA 3EEKA 2ITHA 5E8QA 1DG8A 4FGHA 4KM2A 1RA1A 2FZJA 3ZPCA 4LAHX 5U26A 4NX6A 1DLRA 4CD2A 1RA8A 4HOGA 2D5NA 1DAJA 1DHFA 2D0KA 3DAUA 3QGTA 3NZCX 3QYLA 5ECXA 1LY3A 4XT6A 3HJ3A 2W3AA 4TU5X 4HOFA 3CD2A 2L28A 3SAIA 4FGGA 5JG0X 1KMSA 4H98A 3IA5A 3QLZA 4GH8A 5HVEA 1J3IA 2B3ZA 3NZBX 1U70A 2INQA 3GHCA 3FYWX 3S9UA 1SEJA 3FRFX 3NXTA 1DRAA 3EEMA 2W3BA 3N0HA 6DFRA 3FL9A 3IRNA 3FL8A 3JWCA 4XT5A 4KY4A 4H96A 1E26A 4KJKA 1DG5A 3SQYX 3HBBA 1DR5A 3TQAA 1D1GA 4G3MA 4DFRA 4Q0DA 1M79A 4IXED 3TQ8A 5HF0X 4M7VA 3L3RA 1DRFA 4PTHA 3UM5A 3QL0A 1DYHA 3M08A 4LAGX 3SRRX 1AO8A 4HA7A 2C2SA 3FREX 5U27A 3NXYA 5HUIA 3DG8A 1LY4A 3NU0A 4KY8A 1YHOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KMV A;  1RD7 A;  1HFR A;  3QG2 A;  4FHB A;  2ZZA A;  3OAF A;  1RH3 A;  1RA2 A;  4G8Z X;  3NXV A;  1AI9 A;  4Q67 A;  3Q1H A;  3JWF A;  1VDR A;  1S3U A;  4KJL A;  4OSG A;  1CZ3 A;  3D84 X;  1RX2 A;  5HF2 X;  2G6V A;  3UM8 A;  3FYV X;  3F8Z A;  3NXO A;  1IA3 A;  3FQO A;  3JSU A;  3D80 A;  1LUD A;  1TDR A;  4DDR A;  4ELG A;  4EIG A;  1DG7 A;  3F0B X;  2W9T A;  3NZ9 X;  3JW3 A;  3DGA A;  3FQ0 A;  2DHF A;  2BL9 A;  3EEL A;  1DR4 A;  3NXX A;  3SRQ X;  2W9S A;  1ZDR A;  5CCC A;  3R33 A;  3FY8 X;  2O7P A;  3INV A;  1VJ3 A;  2H2Q A;  4PTJ A;  4QHV A;  3EX8 A;  7DFR A;  1IA2 A;  4HOE A;  2ANQ A;  5HI6 A;  1DHI A;  1DHJ A;  2W3W A;  4XT7 A;  3DRC A;  3GHW A;  3JVX A;  5HT5 A;  1DYR A;  3CLB A;  1DR6 A;  1DRB A;  4M7U A;  3JW5 A;  3QLY A;  1DYI A;  1MVS A;  2LF1 A;  3TD8 A;  4IXG X;  4QJC A;  3F0S X;  4KBN A;  3QLS A;  3FRD X;  3LG4 A;  3IRM A;  1PDB A;  1RB3 A;  1U71 A;  4RGC A;  4IXF X;  1MVT A;  3UM6 A;  3SGY A;  4KYA A;  1RE7 A;  4LEK X;  1HFP A;  2W3V A;  5HSU A;  4EIL A;  1JOL A;  3RO9 A;  4M6J A;  1DIU A;  3K74 A;  3FRB X;  4PSS A;  3QLX A;  3IRO A;  4PDJ A;  3NRR A;  1PD8 A;  3S3V A;  3QLR A;  4DPH A;  2OIP A;  4KJJ A;  4QLF A;  5HPB A;  4QLG A;  2AZN A;  3QYO A;  3GYF A;  3NZ6 X;  4ECK A;  1BZF A;  3F8Y A;  2QK8 A;  5HQZ A;  3JWK A;  5EAJ A;  3KJR A;  5DXV A;  1RX8 A;  3EEJ A;  1RX1 A;  1CD2 A;  1DR3 A;  1S3Y A;  1PD9 A;  1BOZ A;  3TQB A;  1RX7 A;  3I8A X;  3RG9 A;  3JTW A;  4KFJ A;  1DDR A;  1JOM A;  2XW7 A;  1OHK A;  1RF7 A;  4KD7 A;  4P3R A;  4P66 A;  4OR7 A;  2BLA A;  2OBC A;  2W3M A;  4M6K A;  4PST A;  4KNE A;  1RX5 A;  3SR5 X;  3TQ9 A;  3SRS X;  3E0B A;  3ROA A;  1IA4 A;  3SA2 A;  5DFR A;  3KGY A;  3CSE A;  2HM9 A;  3K2H A;  2JYB A;  1RX3 A;  2HXV A;  2W9G A;  3SH2 A;  1RB2 A;  4NX7 A;  2CIG A;  3KFY A;  2BLB A;  4Q0E A;  1RX6 A;  3DL5 A;  4I13 A;  4M2X A;  2KGK A;  3S7A A;  3IX9 A;  4ELH A;  1M7A A;  1HFQ A;  4DPD A;  1DRH A;  4G95 A;  3SRW X;  1DYJ A;  5FDA A;  1DF7 A;  1RA9 A;  1AOE A;  1DDS A;  1RX4 A;  4XT4 A;  3SRU X;  2FZI A;  3K45 A;  4LAE X;  3EIG A;  4X5J A;  2BLC A;  1KLK A;  4QI9 A;  5CC9 A;  2GD9 A;  5HT4 A;  1J3K A;  1J3J A;  4XRB A;  3FY9 X;  4ELB A;  3F0X X;  1DR1 A;  3M09 A;  4KL9 A;  3F91 A;  4X5F A;  3JWM A;  4QLE A;  3ZPG A;  1IA1 A;  3NTZ A;  5HSR A;  3FQV A;  3FQC A;  4X5I A;  1DR2 A;  1RA3 A;  1DRE A;  4P68 A;  2C2T A;  3KY8 A;  1JUV A;  4EIZ A;  3DL6 A;  3NXR A;  1OHJ A;  3FQZ A;  3F0V X;  3QFX A;  3I3R A;  5JA3 A;  1S3V A;  4QJZ D;  1RC4 A;  3F0U X;  2W9H A;  5HVB A;  3F0Q X;  4M6L A;  1M78 A;  2ANO A;  2P4G A;  4KAK A;  4XEC X;  3CL9 A;  2DRC A;  4EJ1 A;  3NZD A;  3IA4 A;  3QL3 A;  3DAT A;  3DFR A;  4DP3 A;  3SA1 A;  3KJS A;  3FS6 A;  1QZF A;  5HQY A;  4X5H A;  2CD2 A;  1DIS A;  4I1N A;  4H95 A;  3GHV A;  2FZH A;  4HA9 A;  1RG7 A;  4P3Q A;  2HQP A;  3GI2 A;  4KLX A;  4KEB A;  3K47 A;  3OCH A;  4PSY A;  4XT8 A;  4H97 A;  4XE6 X;  3FRA X;  1U72 A;  8DFR A;  1DLS A;  4X5G A;  1DR7 A;  3FQF A;  4KM0 A;  3NZA X;  1RX9 A;  1S3W A;  4ELE A;  3VCO A;  3QLW A;  5ECC A;  4ELF A;  4Q6A A;  3EEK A;  2ITH A;  5E8Q A;  1DG8 A;  4FGH A;  4KM2 A;  1RA1 A;  2FZJ A;  3ZPC A;  4LAH X;  5U26 A;  4NX6 A;  1DLR A;  4CD2 A;  1RA8 A;  4HOG A;  2D5N A;  1DAJ A;  1DHF A;  2D0K A;  3DAU A;  3QGT A;  3NZC X;  3QYL A;  5ECX A;  1LY3 A;  4XT6 A;  3HJ3 A;  2W3A A;  4TU5 X;  4HOF A;  3CD2 A;  2L28 A;  3SAI A;  4FGG A;  5JG0 X;  1KMS A;  4H98 A;  3IA5 A;  3QLZ A;  4GH8 A;  5HVE A;  1J3I A;  2B3Z A;  3NZB X;  1U70 A;  2INQ A;  3GHC A;  3FYW X;  3S9U A;  1SEJ A;  3FRF X;  3NXT A;  1DRA A;  3EEM A;  2W3B A;  3N0H A;  6DFR A;  3FL9 A;  3IRN A;  3FL8 A;  3JWC A;  4XT5 A;  4KY4 A;  4H96 A;  1E26 A;  4KJK A;  1DG5 A;  3SQY X;  3HBB A;  1DR5 A;  3TQA A;  1D1G A;  4G3M A;  4DFR A;  4Q0D A;  1M79 A;  4IXE D;  3TQ8 A;  5HF0 X;  4M7V A;  3L3R A;  1DRF A;  4PTH A;  3UM5 A;  3QL0 A;  1DYH A;  3M08 A;  4LAG X;  3SRR X;  1AO8 A;  4HA7 A;  2C2S A;  3FRE X;  5U27 A;  3NXY A;  5HUI A;  3DG8 A;  1LY4 A;  3NU0 A;  4KY8 A;  1YHO A; 
#chains in the Genus database with same CATH topology
 1KMV A;  1RD7 A;  1HFR A;  3QG2 A;  4FHB A;  2ZZA A;  3OAF A;  1RH3 A;  1RA2 A;  4G8Z X;  3NXV A;  1AI9 A;  4Q67 A;  3Q1H A;  3JWF A;  1VDR A;  1S3U A;  4KJL A;  4OSG A;  1CZ3 A;  3D84 X;  1RX2 A;  5HF2 X;  2G6V A;  3UM8 A;  3FYV X;  3F8Z A;  3NXO A;  1IA3 A;  3FQO A;  3JSU A;  3D80 A;  1LUD A;  1TDR A;  4DDR A;  4ELG A;  4EIG A;  1DG7 A;  3F0B X;  2W9T A;  3NZ9 X;  3JW3 A;  3DGA A;  3FQ0 A;  2DHF A;  2BL9 A;  3EEL A;  1DR4 A;  3NXX A;  3SRQ X;  2W9S A;  1ZDR A;  5CCC A;  3R33 A;  3FY8 X;  2O7P A;  3INV A;  1VJ3 A;  2H2Q A;  4PTJ A;  4QHV A;  3EX8 A;  7DFR A;  1IA2 A;  4HOE A;  2ANQ A;  5HI6 A;  1DHI A;  1DHJ A;  2W3W A;  4XT7 A;  3DRC A;  3GHW A;  3JVX A;  5HT5 A;  1DYR A;  3CLB A;  1DR6 A;  1DRB A;  4M7U A;  3JW5 A;  3QLY A;  1DYI A;  1MVS A;  2LF1 A;  3TD8 A;  4IXG X;  4QJC A;  3F0S X;  4KBN A;  3QLS A;  3FRD X;  3LG4 A;  3IRM A;  1PDB A;  1RB3 A;  1U71 A;  4RGC A;  4IXF X;  1MVT A;  3UM6 A;  3SGY A;  4KYA A;  1RE7 A;  4LEK X;  1HFP A;  2W3V A;  5HSU A;  4EIL A;  1JOL A;  3RO9 A;  4M6J A;  1DIU A;  3K74 A;  3FRB X;  4PSS A;  3QLX A;  3IRO A;  4PDJ A;  3NRR A;  1PD8 A;  3S3V A;  3QLR A;  4DPH A;  2OIP A;  4KJJ A;  4QLF A;  5HPB A;  4QLG A;  2AZN A;  3QYO A;  3GYF A;  3NZ6 X;  4ECK A;  1BZF A;  3F8Y A;  2QK8 A;  5HQZ A;  3JWK A;  5EAJ A;  3KJR A;  5DXV A;  1RX8 A;  3EEJ A;  1RX1 A;  1CD2 A;  1DR3 A;  1S3Y A;  1PD9 A;  1BOZ A;  3TQB A;  1RX7 A;  3I8A X;  3RG9 A;  3JTW A;  4KFJ A;  1DDR A;  1JOM A;  2XW7 A;  1OHK A;  1RF7 A;  4KD7 A;  4P3R A;  4P66 A;  4OR7 A;  2BLA A;  2OBC A;  2W3M A;  4M6K A;  4PST A;  4KNE A;  1RX5 A;  3SR5 X;  3TQ9 A;  3SRS X;  3E0B A;  3ROA A;  1IA4 A;  3SA2 A;  5DFR A;  3KGY A;  3CSE A;  2HM9 A;  3K2H A;  2JYB A;  1RX3 A;  2HXV A;  2W9G A;  3SH2 A;  1RB2 A;  4NX7 A;  2CIG A;  3KFY A;  2BLB A;  4Q0E A;  1RX6 A;  3DL5 A;  4I13 A;  4M2X A;  2KGK A;  3S7A A;  3IX9 A;  4ELH A;  1M7A A;  1HFQ A;  4DPD A;  1DRH A;  4G95 A;  3SRW X;  1DYJ A;  5FDA A;  1DF7 A;  1RA9 A;  1AOE A;  1DDS A;  1RX4 A;  4XT4 A;  3SRU X;  2FZI A;  3K45 A;  4LAE X;  3EIG A;  4X5J A;  2BLC A;  1KLK A;  4QI9 A;  5CC9 A;  2GD9 A;  5HT4 A;  1J3K A;  1J3J A;  4XRB A;  3FY9 X;  4ELB A;  3F0X X;  1DR1 A;  3M09 A;  4KL9 A;  3F91 A;  4X5F A;  3JWM A;  4QLE A;  3ZPG A;  1IA1 A;  3NTZ A;  5HSR A;  3FQV A;  3FQC A;  4X5I A;  1DR2 A;  1RA3 A;  1DRE A;  4P68 A;  2C2T A;  3KY8 A;  1JUV A;  4EIZ A;  3DL6 A;  3NXR A;  1OHJ A;  3FQZ A;  3F0V X;  3QFX A;  3I3R A;  5JA3 A;  1S3V A;  4QJZ D;  1RC4 A;  3F0U X;  2W9H A;  5HVB A;  3F0Q X;  4M6L A;  1M78 A;  2ANO A;  2P4G A;  4KAK A;  4XEC X;  3CL9 A;  2DRC A;  4EJ1 A;  3NZD A;  3IA4 A;  3QL3 A;  3DAT A;  3DFR A;  4DP3 A;  3SA1 A;  3KJS A;  3FS6 A;  1QZF A;  5HQY A;  4X5H A;  2CD2 A;  1DIS A;  4I1N A;  4H95 A;  3GHV A;  2FZH A;  4HA9 A;  1RG7 A;  4P3Q A;  2HQP A;  3GI2 A;  4KLX A;  4KEB A;  3K47 A;  3OCH A;  4PSY A;  4XT8 A;  4H97 A;  4XE6 X;  3FRA X;  1U72 A;  8DFR A;  1DLS A;  4X5G A;  1DR7 A;  3FQF A;  4KM0 A;  3NZA X;  1RX9 A;  1S3W A;  4ELE A;  3VCO A;  3QLW A;  5ECC A;  4ELF A;  4Q6A A;  3EEK A;  2ITH A;  5E8Q A;  1DG8 A;  4FGH A;  4KM2 A;  1RA1 A;  2FZJ A;  3ZPC A;  4LAH X;  5U26 A;  4NX6 A;  1DLR A;  4CD2 A;  1RA8 A;  4HOG A;  2D5N A;  1DAJ A;  1DHF A;  2D0K A;  3DAU A;  3QGT A;  3NZC X;  3QYL A;  5ECX A;  1LY3 A;  4XT6 A;  3HJ3 A;  2W3A A;  4TU5 X;  4HOF A;  3CD2 A;  2L28 A;  3SAI A;  4FGG A;  5JG0 X;  1KMS A;  4H98 A;  3IA5 A;  3QLZ A;  4GH8 A;  5HVE A;  1J3I A;  2B3Z A;  3NZB X;  1U70 A;  2INQ A;  3GHC A;  3FYW X;  3S9U A;  1SEJ A;  3FRF X;  3NXT A;  1DRA A;  3EEM A;  2W3B A;  3N0H A;  6DFR A;  3FL9 A;  3IRN A;  3FL8 A;  3JWC A;  4XT5 A;  4KY4 A;  4H96 A;  1E26 A;  4KJK A;  1DG5 A;  3SQY X;  3HBB A;  1DR5 A;  3TQA A;  1D1G A;  4G3M A;  4DFR A;  4Q0D A;  1M79 A;  4IXE D;  3TQ8 A;  5HF0 X;  4M7V A;  3L3R A;  1DRF A;  4PTH A;  3UM5 A;  3QL0 A;  1DYH A;  3M08 A;  4LAG X;  3SRR X;  1AO8 A;  4HA7 A;  2C2S A;  3FRE X;  5U27 A;  3NXY A;  5HUI A;  3DG8 A;  1LY4 A;  3NU0 A;  4KY8 A;  1YHO A; 
#chains in the Genus database with same CATH homology
 1KMV A;  1RD7 A;  1HFR A;  3QG2 A;  4FHB A;  2ZZA A;  3OAF A;  1RH3 A;  1RA2 A;  4G8Z X;  3NXV A;  1AI9 A;  4Q67 A;  3Q1H A;  3JWF A;  1VDR A;  1S3U A;  4KJL A;  4OSG A;  1CZ3 A;  3D84 X;  1RX2 A;  5HF2 X;  2G6V A;  3UM8 A;  3FYV X;  3F8Z A;  3NXO A;  1IA3 A;  3FQO A;  3JSU A;  3D80 A;  1LUD A;  1TDR A;  4DDR A;  4ELG A;  4EIG A;  1DG7 A;  3F0B X;  2W9T A;  3NZ9 X;  3JW3 A;  3DGA A;  3FQ0 A;  2DHF A;  2BL9 A;  3EEL A;  1DR4 A;  3NXX A;  3SRQ X;  2W9S A;  1ZDR A;  5CCC A;  3R33 A;  3FY8 X;  2O7P A;  3INV A;  1VJ3 A;  2H2Q A;  4PTJ A;  4QHV A;  3EX8 A;  7DFR A;  1IA2 A;  4HOE A;  2ANQ A;  5HI6 A;  1DHI A;  1DHJ A;  2W3W A;  4XT7 A;  3DRC A;  3GHW A;  3JVX A;  5HT5 A;  1DYR A;  3CLB A;  1DR6 A;  1DRB A;  4M7U A;  3JW5 A;  3QLY A;  1DYI A;  1MVS A;  2LF1 A;  3TD8 A;  4IXG X;  4QJC A;  3F0S X;  4KBN A;  3QLS A;  3FRD X;  3LG4 A;  3IRM A;  1PDB A;  1RB3 A;  1U71 A;  4RGC A;  4IXF X;  1MVT A;  3UM6 A;  3SGY A;  4KYA A;  1RE7 A;  4LEK X;  1HFP A;  2W3V A;  5HSU A;  4EIL A;  1JOL A;  3RO9 A;  4M6J A;  1DIU A;  3K74 A;  3FRB X;  4PSS A;  3QLX A;  3IRO A;  4PDJ A;  3NRR A;  1PD8 A;  3S3V A;  3QLR A;  4DPH A;  2OIP A;  4KJJ A;  4QLF A;  5HPB A;  4QLG A;  2AZN A;  3QYO A;  3GYF A;  3NZ6 X;  4ECK A;  1BZF A;  3F8Y A;  2QK8 A;  5HQZ A;  3JWK A;  5EAJ A;  3KJR A;  5DXV A;  1RX8 A;  3EEJ A;  1RX1 A;  1CD2 A;  1DR3 A;  1S3Y A;  1PD9 A;  1BOZ A;  3TQB A;  1RX7 A;  3I8A X;  3RG9 A;  3JTW A;  4KFJ A;  1DDR A;  1JOM A;  2XW7 A;  1OHK A;  1RF7 A;  4KD7 A;  4P3R A;  4P66 A;  4OR7 A;  2BLA A;  2OBC A;  2W3M A;  4M6K A;  4PST A;  4KNE A;  1RX5 A;  3SR5 X;  3TQ9 A;  3SRS X;  3E0B A;  3ROA A;  1IA4 A;  3SA2 A;  5DFR A;  3KGY A;  3CSE A;  2HM9 A;  3K2H A;  2JYB A;  1RX3 A;  2HXV A;  2W9G A;  3SH2 A;  1RB2 A;  4NX7 A;  2CIG A;  3KFY A;  2BLB A;  4Q0E A;  1RX6 A;  3DL5 A;  4I13 A;  4M2X A;  2KGK A;  3S7A A;  3IX9 A;  4ELH A;  1M7A A;  1HFQ A;  4DPD A;  1DRH A;  4G95 A;  3SRW X;  1DYJ A;  5FDA A;  1DF7 A;  1RA9 A;  1AOE A;  1DDS A;  1RX4 A;  4XT4 A;  3SRU X;  2FZI A;  3K45 A;  4LAE X;  3EIG A;  4X5J A;  2BLC A;  1KLK A;  4QI9 A;  5CC9 A;  2GD9 A;  5HT4 A;  1J3K A;  1J3J A;  4XRB A;  3FY9 X;  4ELB A;  3F0X X;  1DR1 A;  3M09 A;  4KL9 A;  3F91 A;  4X5F A;  3JWM A;  4QLE A;  3ZPG A;  1IA1 A;  3NTZ A;  5HSR A;  3FQV A;  3FQC A;  4X5I A;  1DR2 A;  1RA3 A;  1DRE A;  4P68 A;  2C2T A;  3KY8 A;  1JUV A;  4EIZ A;  3DL6 A;  3NXR A;  1OHJ A;  3FQZ A;  3F0V X;  3QFX A;  3I3R A;  5JA3 A;  1S3V A;  4QJZ D;  1RC4 A;  3F0U X;  2W9H A;  5HVB A;  3F0Q X;  4M6L A;  1M78 A;  2ANO A;  2P4G A;  4KAK A;  4XEC X;  3CL9 A;  2DRC A;  4EJ1 A;  3NZD A;  3IA4 A;  3QL3 A;  3DAT A;  3DFR A;  4DP3 A;  3SA1 A;  3KJS A;  3FS6 A;  1QZF A;  5HQY A;  4X5H A;  2CD2 A;  1DIS A;  4I1N A;  4H95 A;  3GHV A;  2FZH A;  4HA9 A;  1RG7 A;  4P3Q A;  2HQP A;  3GI2 A;  4KLX A;  4KEB A;  3K47 A;  3OCH A;  4PSY A;  4XT8 A;  4H97 A;  4XE6 X;  3FRA X;  1U72 A;  8DFR A;  1DLS A;  4X5G A;  1DR7 A;  3FQF A;  4KM0 A;  3NZA X;  1RX9 A;  1S3W A;  4ELE A;  3VCO A;  3QLW A;  5ECC A;  4ELF A;  4Q6A A;  3EEK A;  2ITH A;  5E8Q A;  1DG8 A;  4FGH A;  4KM2 A;  1RA1 A;  2FZJ A;  3ZPC A;  4LAH X;  5U26 A;  4NX6 A;  1DLR A;  4CD2 A;  1RA8 A;  4HOG A;  2D5N A;  1DAJ A;  1DHF A;  2D0K A;  3DAU A;  3QGT A;  3NZC X;  3QYL A;  5ECX A;  1LY3 A;  4XT6 A;  3HJ3 A;  2W3A A;  4TU5 X;  4HOF A;  3CD2 A;  2L28 A;  3SAI A;  4FGG A;  5JG0 X;  1KMS A;  4H98 A;  3IA5 A;  3QLZ A;  4GH8 A;  5HVE A;  1J3I A;  2B3Z A;  3NZB X;  1U70 A;  2INQ A;  3GHC A;  3FYW X;  3S9U A;  1SEJ A;  3FRF X;  3NXT A;  1DRA A;  3EEM A;  2W3B A;  3N0H A;  6DFR A;  3FL9 A;  3IRN A;  3FL8 A;  3JWC A;  4XT5 A;  4KY4 A;  4H96 A;  1E26 A;  4KJK A;  1DG5 A;  3SQY X;  3HBB A;  1DR5 A;  3TQA A;  1D1G A;  4G3M A;  4DFR A;  4Q0D A;  1M79 A;  4IXE D;  3TQ8 A;  5HF0 X;  4M7V A;  3L3R A;  1DRF A;  4PTH A;  3UM5 A;  3QL0 A;  1DYH A;  3M08 A;  4LAG X;  3SRR X;  1AO8 A;  4HA7 A;  2C2S A;  3FRE X;  5U27 A;  3NXY A;  5HUI A;  3DG8 A;  1LY4 A;  3NU0 A;  4KY8 A;  1YHO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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