3RG9A

Trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with wr99210
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
218
structure length
218
Chain Sequence
RPPLRPFSVVVASDEKGGIGDGGTIPWEIPEDMQYFRRVTTNLRGKNVKPSPSKRNAVVMGRKTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGIPDPIKRAEAANDVVAVNGGLEDALRMLVSKEHTSSIETVFCIGGGTIYKQALCAPCVNVLQAIHRTVVRPASNSCSVFFDIPAAGTKTPEGLELVRESITDERVSTGAGGKKYQFEKLVPRN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Trypanosoma brucei rhodesiense
publication title Trypanosomal dihydrofolate reductase reveals natural antifolate resistance
pubmed doi rcsb
molecule keywords Bifunctional dihydrofolate reductase-thymidylate synthase
total genus 58
structure length 218
sequence length 218
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-04-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3rg9A00
4QJCA 5JA3A 4LEKX 3N0HA 3JW3A 3NZ9X 3DRCA 3CL9A 1DR7A 3DAUA 2OBCA 4KLXA 3SRQX 4DP3A 1M78A 4G3MA 3FREX 3CSEA 3HJ3A 4TU5X 1DF7A 1E26A 3S7AA 2D0KA 1U70A 2GD9A 2W9SA 2BLBA 2ITHA 3FQFA 4H98A 3GHWA 3RO9A 1S3VA 2B3ZA 3HBBA 2L28A 1DLSA 4M6KA 4KBNA 1HFRA 2W3WA 4EJ1A 4XECX 1RX3A 1DRBA 3FQZA 2FZJA 4LAEX 1DRHA 1J3KA 1RA9A 3SGYA 1VJ3A 3SAIA 2FZHA 3EIGA 4G95A 3OCHA 1RF7A 2W3BA 1PD9A 3NZAX 1MVTA 3IRNA 1PD8A 3FRDX 1AOEA 4X5JA 3QYLA 1RX1A 1DG5A 1DHFA 4KJJA 2LF1A 4DPHA 1RA2A 1QZFA 3TQ8A 1TDRA 2D5NA 7DFRA 2W9GA 5HVEA 3S9UA 3FRAX 4QLFA 3SQYX 2HQPA 3JTWA 4M6LA 1DREA 3NZDA 2ANOA 3F8ZA 3CD2A 3M08A 4PDJA 5EAJA 3GI2A 3FQ0A 1RA8A 1RB2A 4XT4A 3F91A 4H96A 1S3WA 5HUIA 1HFPA 5HPBA 3I8AX 2W3MA 4ELEA 3NZBX 4HOEA 4FGHA 3QLYA 3NZCX 4XT8A 1ZDRA 3QYOA 1RA1A 5ECXA 1DDSA 3QFXA 3TD8A 3INVA 3D84X 4HA7A 1OHJA 3DL5A 1RX9A 1DR2A 3IA4A 3IRMA 3KGYA 4DFRA 1YHOA 4G8ZX 3FYVX 3JSUA 3K2HA 4P66A 4HOGA 4X5HA 2OIPA 3SR5X 3M09A 3EX8A 3TQBA 3UM5A 3KFYA 1DYRA 3F0VX 4EIZA 4PSSA 1RX7A 4KM2A 3IROA 2CD2A 1RX5A 3FY9X 3TQ9A 1DLRA 4GH8A 1M7AA 2W9HA 1DYHA 1DR1A 4QI9A 3IA5A 2ZZAA 3NZ6X 1DHJA 1DR6A 2AZNA 4LAHX 2QK8A 5HT5A 4ELHA 4FGGA 3QLWA 3K47A 3UM8A 1AI9A 4EIGA 3QLZA 3JWKA 4ELGA 3UM6A 3KJRA 1RX2A 4KY8A 4QLEA 1CZ3A 4HA9A 3FL9A 4H97A 1DIUA 3EEKA 4Q0EA 1RX8A 1MVSA 4QHVA 4I1NA 1JUVA 1S3YA 3S3VA 4LAGX 4KAKA 5CCCA 1RX4A 5U27A 1SEJA 3TQAA 8DFRA 3CLBA 4X5GA 3SA1A 4HOFA 3F0UX 3K45A 4KJLA 4XT5A 3SRWX 5HSUA 3K74A 3F0QX 3FQCA 4KD7A 5ECCA 4QJZD 4X5IA 4KEBA 1J3IA 1AO8A 1JOLA 4X5FA 3QG2A 4Q67A 1KMSA 3F0SX 2INQA 3EEMA 2H2QA 2BLCA 4XT6A 3R33A 2ANQA 2W9TA 3SRSX 3SH2A 3VCOA 3GYFA 1LY3A 4KYAA 4KJKA 4ELFA 4Q6AA 3DL6A 5U26A 4XE6X 3NRRA 1KLKA 3DG8A 4P3QA 5HT4A 3FL8A 3NTZA 5HF0X 1DYIA 2BLAA 4QLGA 1OHKA 3FYWX 5DFRA 4XT7A 3JWFA 3DFRA 1BZFA 3I3RA 3L3RA 3NXXA 2DHFA 2HM9A 3JVXA 3SRUX 4M7UA 5E8QA 4FHBA 3QL0A 1IA4A 4P3RA 3FY8X 1DYJA 1DG8A 3IX9A 4DPDA 3NXVA 3FS6A 3SA2A 2P4GA 1DR5A 4IXED 4OR7A 2HXVA 5HVBA 1IA2A 5HF2X 3ZPCA 1DG7A 4I13A 3NXTA 1U72A 4KL9A 3Q1HA 3F8YA 3FQOA 3OAFA 2C2TA 3QLSA 4IXGX 2KGKA 3NU0A 4OSGA 5HQZA 3ROAA 1DR4A 5HI6A 4Q0DA 4ELBA 3D80A 4RGCA 1S3UA 3JWCA 1BOZA 1RX6A 3FRBX 3JW5A 3ZPGA 1LY4A 3FQVA 3GHVA 1RH3A 1RC4A 1U71A 1HFQA 3LG4A 4KM0A 2O7PA 3QLXA 2C2SA 4KFJA 1D1GA 4XRBA 3DGAA 1KMVA 2G6VA 4NX6A 4PSTA 4KY4A 1J3JA 3JWMA 4NX7A 1M79A 3FRFX 2W3VA 4ECKA 3NXOA 3KJSA 1DDRA 1RB3A 1RE7A 1PDBA 4PTJA 5HSRA 1VDRA 3QLRA 1DRFA 2BL9A 4PSYA 3QL3A 3SRRX 1LUDA 1CD2A 2W3AA 3F0BX 4P68A 3F0XX 5JG0X 3E0BA 5FDAA 2DRCA 1DHIA 4IXFX 1JOMA 5HQYA 1RG7A 3RG9A 1IA3A 2JYBA 4M7VA 4EILA 4CD2A 4KNEA 6DFRA 3NXRA 3GHCA 1DRAA 1RA3A 4DDRA 3EEJA 5DXVA 1DISA 3EELA 1DR3A 1RD7A 4H95A 2CIGA 2FZIA 4M2XA 3NXYA 1IA1A 3KY8A 3DATA 4PTHA 3QGTA 4M6JA 2XW7A 5CC9A 1DAJA
chains in the Genus database with same CATH superfamily
4QJCA 5JA3A 4LEKX 3N0HA 3JW3A 3NZ9X 3DRCA 3CL9A 1DR7A 3DAUA 2OBCA 4KLXA 3SRQX 4DP3A 1M78A 4G3MA 3FREX 3CSEA 3HJ3A 4TU5X 1DF7A 1E26A 3S7AA 2D0KA 1U70A 2GD9A 2W9SA 2BLBA 2ITHA 3FQFA 4H98A 3GHWA 3RO9A 1S3VA 2B3ZA 3HBBA 2L28A 1DLSA 4M6KA 4KBNA 1HFRA 2W3WA 4EJ1A 4XECX 1RX3A 1DRBA 3FQZA 2FZJA 4LAEX 1DRHA 1J3KA 1RA9A 3SGYA 1VJ3A 3SAIA 2FZHA 3EIGA 4G95A 3OCHA 1RF7A 2W3BA 1PD9A 3NZAX 1MVTA 3IRNA 1PD8A 3FRDX 1AOEA 4X5JA 3QYLA 1RX1A 1DG5A 1DHFA 4KJJA 2LF1A 4DPHA 1RA2A 1QZFA 3TQ8A 1TDRA 2D5NA 7DFRA 2W9GA 5HVEA 3S9UA 3FRAX 4QLFA 3SQYX 2HQPA 3JTWA 4M6LA 1DREA 3NZDA 2ANOA 3F8ZA 3CD2A 3M08A 4PDJA 5EAJA 3GI2A 3FQ0A 1RA8A 1RB2A 4XT4A 3F91A 4H96A 1S3WA 5HUIA 1HFPA 5HPBA 3I8AX 2W3MA 4ELEA 3NZBX 4HOEA 4FGHA 3QLYA 3NZCX 4XT8A 1ZDRA 3QYOA 1RA1A 5ECXA 1DDSA 3QFXA 3TD8A 3INVA 3D84X 4HA7A 1OHJA 3DL5A 1RX9A 1DR2A 3IA4A 3IRMA 3KGYA 4DFRA 1YHOA 4G8ZX 3FYVX 3JSUA 3K2HA 4P66A 4HOGA 4X5HA 2OIPA 3SR5X 3M09A 3EX8A 3TQBA 3UM5A 3KFYA 1DYRA 3F0VX 4EIZA 4PSSA 1RX7A 4KM2A 3IROA 2CD2A 1RX5A 3FY9X 3TQ9A 1DLRA 4GH8A 1M7AA 2W9HA 1DYHA 1DR1A 4QI9A 3IA5A 2ZZAA 3NZ6X 1DHJA 1DR6A 2AZNA 4LAHX 2QK8A 5HT5A 4ELHA 4FGGA 3QLWA 3K47A 3UM8A 1AI9A 4EIGA 3QLZA 3JWKA 4ELGA 3UM6A 3KJRA 1RX2A 4KY8A 4QLEA 1CZ3A 4HA9A 3FL9A 4H97A 1DIUA 3EEKA 4Q0EA 1RX8A 1MVSA 4QHVA 4I1NA 1JUVA 1S3YA 3S3VA 4LAGX 4KAKA 5CCCA 1RX4A 5U27A 1SEJA 3TQAA 8DFRA 3CLBA 4X5GA 3SA1A 4HOFA 3F0UX 3K45A 4KJLA 4XT5A 3SRWX 5HSUA 3K74A 3F0QX 3FQCA 4KD7A 5ECCA 4QJZD 4X5IA 4KEBA 1J3IA 1AO8A 1JOLA 4X5FA 3QG2A 4Q67A 1KMSA 3F0SX 2INQA 3EEMA 2H2QA 2BLCA 4XT6A 3R33A 2ANQA 2W9TA 3SRSX 3SH2A 3VCOA 3GYFA 1LY3A 4KYAA 4KJKA 4ELFA 4Q6AA 3DL6A 5U26A 4XE6X 3NRRA 1KLKA 3DG8A 4P3QA 5HT4A 3FL8A 3NTZA 5HF0X 1DYIA 2BLAA 4QLGA 1OHKA 3FYWX 5DFRA 4XT7A 3JWFA 3DFRA 1BZFA 3I3RA 3L3RA 3NXXA 2DHFA 2HM9A 3JVXA 3SRUX 4M7UA 5E8QA 4FHBA 3QL0A 1IA4A 4P3RA 3FY8X 1DYJA 1DG8A 3IX9A 4DPDA 3NXVA 3FS6A 3SA2A 2P4GA 1DR5A 4IXED 4OR7A 2HXVA 5HVBA 1IA2A 5HF2X 3ZPCA 1DG7A 4I13A 3NXTA 1U72A 4KL9A 3Q1HA 3F8YA 3FQOA 3OAFA 2C2TA 3QLSA 4IXGX 2KGKA 3NU0A 4OSGA 5HQZA 3ROAA 1DR4A 5HI6A 4Q0DA 4ELBA 3D80A 4RGCA 1S3UA 3JWCA 1BOZA 1RX6A 3FRBX 3JW5A 3ZPGA 1LY4A 3FQVA 3GHVA 1RH3A 1RC4A 1U71A 1HFQA 3LG4A 4KM0A 2O7PA 3QLXA 2C2SA 4KFJA 1D1GA 4XRBA 3DGAA 1KMVA 2G6VA 4NX6A 4PSTA 4KY4A 1J3JA 3JWMA 4NX7A 1M79A 3FRFX 2W3VA 4ECKA 3NXOA 3KJSA 1DDRA 1RB3A 1RE7A 1PDBA 4PTJA 5HSRA 1VDRA 3QLRA 1DRFA 2BL9A 4PSYA 3QL3A 3SRRX 1LUDA 1CD2A 2W3AA 3F0BX 4P68A 3F0XX 5JG0X 3E0BA 5FDAA 2DRCA 1DHIA 4IXFX 1JOMA 5HQYA 1RG7A 3RG9A 1IA3A 2JYBA 4M7VA 4EILA 4CD2A 4KNEA 6DFRA 3NXRA 3GHCA 1DRAA 1RA3A 4DDRA 3EEJA 5DXVA 1DISA 3EELA 1DR3A 1RD7A 4H95A 2CIGA 2FZIA 4M2XA 3NXYA 1IA1A 3KY8A 3DATA 4PTHA 3QGTA 4M6JA 2XW7A 5CC9A 1DAJA
chains in the Genus database with same CATH topology
4QJCA 5JA3A 4LEKX 3N0HA 3JW3A 3NZ9X 3DRCA 3CL9A 1DR7A 3DAUA 2OBCA 4KLXA 3SRQX 4DP3A 1M78A 4G3MA 3FREX 3CSEA 3HJ3A 4TU5X 1DF7A 1E26A 3S7AA 2D0KA 1U70A 2GD9A 2W9SA 2BLBA 2ITHA 3FQFA 4H98A 3GHWA 3RO9A 1S3VA 2B3ZA 3HBBA 2L28A 1DLSA 4M6KA 4KBNA 1HFRA 2W3WA 4EJ1A 4XECX 1RX3A 1DRBA 3FQZA 2FZJA 4LAEX 1DRHA 1J3KA 1RA9A 3SGYA 1VJ3A 3SAIA 2FZHA 3EIGA 4G95A 3OCHA 1RF7A 2W3BA 1PD9A 3NZAX 1MVTA 3IRNA 1PD8A 3FRDX 1AOEA 4X5JA 3QYLA 1RX1A 1DG5A 1DHFA 4KJJA 2LF1A 4DPHA 1RA2A 1QZFA 3TQ8A 1TDRA 2D5NA 7DFRA 2W9GA 5HVEA 3S9UA 3FRAX 4QLFA 3SQYX 2HQPA 3JTWA 4M6LA 1DREA 3NZDA 2ANOA 3F8ZA 3CD2A 3M08A 4PDJA 5EAJA 3GI2A 3FQ0A 1RA8A 1RB2A 4XT4A 3F91A 4H96A 1S3WA 5HUIA 1HFPA 5HPBA 3I8AX 2W3MA 4ELEA 3NZBX 4HOEA 4FGHA 3QLYA 3NZCX 4XT8A 1ZDRA 3QYOA 1RA1A 5ECXA 1DDSA 3QFXA 3TD8A 3INVA 3D84X 4HA7A 1OHJA 3DL5A 1RX9A 1DR2A 3IA4A 3IRMA 3KGYA 4DFRA 1YHOA 4G8ZX 3FYVX 3JSUA 3K2HA 4P66A 4HOGA 4X5HA 2OIPA 3SR5X 3M09A 3EX8A 3TQBA 3UM5A 3KFYA 1DYRA 3F0VX 4EIZA 4PSSA 1RX7A 4KM2A 3IROA 2CD2A 1RX5A 3FY9X 3TQ9A 1DLRA 4GH8A 1M7AA 2W9HA 1DYHA 1DR1A 4QI9A 3IA5A 2ZZAA 3NZ6X 1DHJA 1DR6A 2AZNA 4LAHX 2QK8A 5HT5A 4ELHA 4FGGA 3QLWA 3K47A 3UM8A 1AI9A 4EIGA 3QLZA 3JWKA 4ELGA 3UM6A 3KJRA 1RX2A 4KY8A 4QLEA 1CZ3A 4HA9A 3FL9A 4H97A 1DIUA 3EEKA 4Q0EA 1RX8A 1MVSA 4QHVA 4I1NA 1JUVA 1S3YA 3S3VA 4LAGX 4KAKA 5CCCA 1RX4A 5U27A 1SEJA 3TQAA 8DFRA 3CLBA 4X5GA 3SA1A 4HOFA 3F0UX 3K45A 4KJLA 4XT5A 3SRWX 5HSUA 3K74A 3F0QX 3FQCA 4KD7A 5ECCA 4QJZD 4X5IA 4KEBA 1J3IA 1AO8A 1JOLA 4X5FA 3QG2A 4Q67A 1KMSA 3F0SX 2INQA 3EEMA 2H2QA 2BLCA 4XT6A 3R33A 2ANQA 2W9TA 3SRSX 3SH2A 3VCOA 3GYFA 1LY3A 4KYAA 4KJKA 4ELFA 4Q6AA 3DL6A 5U26A 4XE6X 3NRRA 1KLKA 3DG8A 4P3QA 5HT4A 3FL8A 3NTZA 5HF0X 1DYIA 2BLAA 4QLGA 1OHKA 3FYWX 5DFRA 4XT7A 3JWFA 3DFRA 1BZFA 3I3RA 3L3RA 3NXXA 2DHFA 2HM9A 3JVXA 3SRUX 4M7UA 5E8QA 4FHBA 3QL0A 1IA4A 4P3RA 3FY8X 1DYJA 1DG8A 3IX9A 4DPDA 3NXVA 3FS6A 3SA2A 2P4GA 1DR5A 4IXED 4OR7A 2HXVA 5HVBA 1IA2A 5HF2X 3ZPCA 1DG7A 4I13A 3NXTA 1U72A 4KL9A 3Q1HA 3F8YA 3FQOA 3OAFA 2C2TA 3QLSA 4IXGX 2KGKA 3NU0A 4OSGA 5HQZA 3ROAA 1DR4A 5HI6A 4Q0DA 4ELBA 3D80A 4RGCA 1S3UA 3JWCA 1BOZA 1RX6A 3FRBX 3JW5A 3ZPGA 1LY4A 3FQVA 3GHVA 1RH3A 1RC4A 1U71A 1HFQA 3LG4A 4KM0A 2O7PA 3QLXA 2C2SA 4KFJA 1D1GA 4XRBA 3DGAA 1KMVA 2G6VA 4NX6A 4PSTA 4KY4A 1J3JA 3JWMA 4NX7A 1M79A 3FRFX 2W3VA 4ECKA 3NXOA 3KJSA 1DDRA 1RB3A 1RE7A 1PDBA 4PTJA 5HSRA 1VDRA 3QLRA 1DRFA 2BL9A 4PSYA 3QL3A 3SRRX 1LUDA 1CD2A 2W3AA 3F0BX 4P68A 3F0XX 5JG0X 3E0BA 5FDAA 2DRCA 1DHIA 4IXFX 1JOMA 5HQYA 1RG7A 3RG9A 1IA3A 2JYBA 4M7VA 4EILA 4CD2A 4KNEA 6DFRA 3NXRA 3GHCA 1DRAA 1RA3A 4DDRA 3EEJA 5DXVA 1DISA 3EELA 1DR3A 1RD7A 4H95A 2CIGA 2FZIA 4M2XA 3NXYA 1IA1A 3KY8A 3DATA 4PTHA 3QGTA 4M6JA 2XW7A 5CC9A 1DAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QJC A;  5JA3 A;  4LEK X;  3N0H A;  3JW3 A;  3NZ9 X;  3DRC A;  3CL9 A;  1DR7 A;  3DAU A;  2OBC A;  4KLX A;  3SRQ X;  4DP3 A;  1M78 A;  4G3M A;  3FRE X;  3CSE A;  3HJ3 A;  4TU5 X;  1DF7 A;  1E26 A;  3S7A A;  2D0K A;  1U70 A;  2GD9 A;  2W9S A;  2BLB A;  2ITH A;  3FQF A;  4H98 A;  3GHW A;  3RO9 A;  1S3V A;  2B3Z A;  3HBB A;  2L28 A;  1DLS A;  4M6K A;  4KBN A;  1HFR A;  2W3W A;  4EJ1 A;  4XEC X;  1RX3 A;  1DRB A;  3FQZ A;  2FZJ A;  4LAE X;  1DRH A;  1J3K A;  1RA9 A;  3SGY A;  1VJ3 A;  3SAI A;  2FZH A;  3EIG A;  4G95 A;  3OCH A;  1RF7 A;  2W3B A;  1PD9 A;  3NZA X;  1MVT A;  3IRN A;  1PD8 A;  3FRD X;  1AOE A;  4X5J A;  3QYL A;  1RX1 A;  1DG5 A;  1DHF A;  4KJJ A;  2LF1 A;  4DPH A;  1RA2 A;  1QZF A;  3TQ8 A;  1TDR A;  2D5N A;  7DFR A;  2W9G A;  5HVE A;  3S9U A;  3FRA X;  4QLF A;  3SQY X;  2HQP A;  3JTW A;  4M6L A;  1DRE A;  3NZD A;  2ANO A;  3F8Z A;  3CD2 A;  3M08 A;  4PDJ A;  5EAJ A;  3GI2 A;  3FQ0 A;  1RA8 A;  1RB2 A;  4XT4 A;  3F91 A;  4H96 A;  1S3W A;  5HUI A;  1HFP A;  5HPB A;  3I8A X;  2W3M A;  4ELE A;  3NZB X;  4HOE A;  4FGH A;  3QLY A;  3NZC X;  4XT8 A;  1ZDR A;  3QYO A;  1RA1 A;  5ECX A;  1DDS A;  3QFX A;  3TD8 A;  3INV A;  3D84 X;  4HA7 A;  1OHJ A;  3DL5 A;  1RX9 A;  1DR2 A;  3IA4 A;  3IRM A;  3KGY A;  4DFR A;  1YHO A;  4G8Z X;  3FYV X;  3JSU A;  3K2H A;  4P66 A;  4HOG A;  4X5H A;  2OIP A;  3SR5 X;  3M09 A;  3EX8 A;  3TQB A;  3UM5 A;  3KFY A;  1DYR A;  3F0V X;  4EIZ A;  4PSS A;  1RX7 A;  4KM2 A;  3IRO A;  2CD2 A;  1RX5 A;  3FY9 X;  3TQ9 A;  1DLR A;  4GH8 A;  1M7A A;  2W9H A;  1DYH A;  1DR1 A;  4QI9 A;  3IA5 A;  2ZZA A;  3NZ6 X;  1DHJ A;  1DR6 A;  2AZN A;  4LAH X;  2QK8 A;  5HT5 A;  4ELH A;  4FGG A;  3QLW A;  3K47 A;  3UM8 A;  1AI9 A;  4EIG A;  3QLZ A;  3JWK A;  4ELG A;  3UM6 A;  3KJR A;  1RX2 A;  4KY8 A;  4QLE A;  1CZ3 A;  4HA9 A;  3FL9 A;  4H97 A;  1DIU A;  3EEK A;  4Q0E A;  1RX8 A;  1MVS A;  4QHV A;  4I1N A;  1JUV A;  1S3Y A;  3S3V A;  4LAG X;  4KAK A;  5CCC A;  1RX4 A;  5U27 A;  1SEJ A;  3TQA A;  8DFR A;  3CLB A;  4X5G A;  3SA1 A;  4HOF A;  3F0U X;  3K45 A;  4KJL A;  4XT5 A;  3SRW X;  5HSU A;  3K74 A;  3F0Q X;  3FQC A;  4KD7 A;  5ECC A;  4QJZ D;  4X5I A;  4KEB A;  1J3I A;  1AO8 A;  1JOL A;  4X5F A;  3QG2 A;  4Q67 A;  1KMS A;  3F0S X;  2INQ A;  3EEM A;  2H2Q A;  2BLC A;  4XT6 A;  3R33 A;  2ANQ A;  2W9T A;  3SRS X;  3SH2 A;  3VCO A;  3GYF A;  1LY3 A;  4KYA A;  4KJK A;  4ELF A;  4Q6A A;  3DL6 A;  5U26 A;  4XE6 X;  3NRR A;  1KLK A;  3DG8 A;  4P3Q A;  5HT4 A;  3FL8 A;  3NTZ A;  5HF0 X;  1DYI A;  2BLA A;  4QLG A;  1OHK A;  3FYW X;  5DFR A;  4XT7 A;  3JWF A;  3DFR A;  1BZF A;  3I3R A;  3L3R A;  3NXX A;  2DHF A;  2HM9 A;  3JVX A;  3SRU X;  4M7U A;  5E8Q A;  4FHB A;  3QL0 A;  1IA4 A;  4P3R A;  3FY8 X;  1DYJ A;  1DG8 A;  3IX9 A;  4DPD A;  3NXV A;  3FS6 A;  3SA2 A;  2P4G A;  1DR5 A;  4IXE D;  4OR7 A;  2HXV A;  5HVB A;  1IA2 A;  5HF2 X;  3ZPC A;  1DG7 A;  4I13 A;  3NXT A;  1U72 A;  4KL9 A;  3Q1H A;  3F8Y A;  3FQO A;  3OAF A;  2C2T A;  3QLS A;  4IXG X;  2KGK A;  3NU0 A;  4OSG A;  5HQZ A;  3ROA A;  1DR4 A;  5HI6 A;  4Q0D A;  4ELB A;  3D80 A;  4RGC A;  1S3U A;  3JWC A;  1BOZ A;  1RX6 A;  3FRB X;  3JW5 A;  3ZPG A;  1LY4 A;  3FQV A;  3GHV A;  1RH3 A;  1RC4 A;  1U71 A;  1HFQ A;  3LG4 A;  4KM0 A;  2O7P A;  3QLX A;  2C2S A;  4KFJ A;  1D1G A;  4XRB A;  3DGA A;  1KMV A;  2G6V A;  4NX6 A;  4PST A;  4KY4 A;  1J3J A;  3JWM A;  4NX7 A;  1M79 A;  3FRF X;  2W3V A;  4ECK A;  3NXO A;  3KJS A;  1DDR A;  1RB3 A;  1RE7 A;  1PDB A;  4PTJ A;  5HSR A;  1VDR A;  3QLR A;  1DRF A;  2BL9 A;  4PSY A;  3QL3 A;  3SRR X;  1LUD A;  1CD2 A;  2W3A A;  3F0B X;  4P68 A;  3F0X X;  5JG0 X;  3E0B A;  5FDA A;  2DRC A;  1DHI A;  4IXF X;  1JOM A;  5HQY A;  1RG7 A;  3RG9 A;  1IA3 A;  2JYB A;  4M7V A;  4EIL A;  4CD2 A;  4KNE A;  6DFR A;  3NXR A;  3GHC A;  1DRA A;  1RA3 A;  4DDR A;  3EEJ A;  5DXV A;  1DIS A;  3EEL A;  1DR3 A;  1RD7 A;  4H95 A;  2CIG A;  2FZI A;  4M2X A;  3NXY A;  1IA1 A;  3KY8 A;  3DAT A;  4PTH A;  3QGT A;  4M6J A;  2XW7 A;  5CC9 A;  1DAJ A; 
#chains in the Genus database with same CATH topology
 4QJC A;  5JA3 A;  4LEK X;  3N0H A;  3JW3 A;  3NZ9 X;  3DRC A;  3CL9 A;  1DR7 A;  3DAU A;  2OBC A;  4KLX A;  3SRQ X;  4DP3 A;  1M78 A;  4G3M A;  3FRE X;  3CSE A;  3HJ3 A;  4TU5 X;  1DF7 A;  1E26 A;  3S7A A;  2D0K A;  1U70 A;  2GD9 A;  2W9S A;  2BLB A;  2ITH A;  3FQF A;  4H98 A;  3GHW A;  3RO9 A;  1S3V A;  2B3Z A;  3HBB A;  2L28 A;  1DLS A;  4M6K A;  4KBN A;  1HFR A;  2W3W A;  4EJ1 A;  4XEC X;  1RX3 A;  1DRB A;  3FQZ A;  2FZJ A;  4LAE X;  1DRH A;  1J3K A;  1RA9 A;  3SGY A;  1VJ3 A;  3SAI A;  2FZH A;  3EIG A;  4G95 A;  3OCH A;  1RF7 A;  2W3B A;  1PD9 A;  3NZA X;  1MVT A;  3IRN A;  1PD8 A;  3FRD X;  1AOE A;  4X5J A;  3QYL A;  1RX1 A;  1DG5 A;  1DHF A;  4KJJ A;  2LF1 A;  4DPH A;  1RA2 A;  1QZF A;  3TQ8 A;  1TDR A;  2D5N A;  7DFR A;  2W9G A;  5HVE A;  3S9U A;  3FRA X;  4QLF A;  3SQY X;  2HQP A;  3JTW A;  4M6L A;  1DRE A;  3NZD A;  2ANO A;  3F8Z A;  3CD2 A;  3M08 A;  4PDJ A;  5EAJ A;  3GI2 A;  3FQ0 A;  1RA8 A;  1RB2 A;  4XT4 A;  3F91 A;  4H96 A;  1S3W A;  5HUI A;  1HFP A;  5HPB A;  3I8A X;  2W3M A;  4ELE A;  3NZB X;  4HOE A;  4FGH A;  3QLY A;  3NZC X;  4XT8 A;  1ZDR A;  3QYO A;  1RA1 A;  5ECX A;  1DDS A;  3QFX A;  3TD8 A;  3INV A;  3D84 X;  4HA7 A;  1OHJ A;  3DL5 A;  1RX9 A;  1DR2 A;  3IA4 A;  3IRM A;  3KGY A;  4DFR A;  1YHO A;  4G8Z X;  3FYV X;  3JSU A;  3K2H A;  4P66 A;  4HOG A;  4X5H A;  2OIP A;  3SR5 X;  3M09 A;  3EX8 A;  3TQB A;  3UM5 A;  3KFY A;  1DYR A;  3F0V X;  4EIZ A;  4PSS A;  1RX7 A;  4KM2 A;  3IRO A;  2CD2 A;  1RX5 A;  3FY9 X;  3TQ9 A;  1DLR A;  4GH8 A;  1M7A A;  2W9H A;  1DYH A;  1DR1 A;  4QI9 A;  3IA5 A;  2ZZA A;  3NZ6 X;  1DHJ A;  1DR6 A;  2AZN A;  4LAH X;  2QK8 A;  5HT5 A;  4ELH A;  4FGG A;  3QLW A;  3K47 A;  3UM8 A;  1AI9 A;  4EIG A;  3QLZ A;  3JWK A;  4ELG A;  3UM6 A;  3KJR A;  1RX2 A;  4KY8 A;  4QLE A;  1CZ3 A;  4HA9 A;  3FL9 A;  4H97 A;  1DIU A;  3EEK A;  4Q0E A;  1RX8 A;  1MVS A;  4QHV A;  4I1N A;  1JUV A;  1S3Y A;  3S3V A;  4LAG X;  4KAK A;  5CCC A;  1RX4 A;  5U27 A;  1SEJ A;  3TQA A;  8DFR A;  3CLB A;  4X5G A;  3SA1 A;  4HOF A;  3F0U X;  3K45 A;  4KJL A;  4XT5 A;  3SRW X;  5HSU A;  3K74 A;  3F0Q X;  3FQC A;  4KD7 A;  5ECC A;  4QJZ D;  4X5I A;  4KEB A;  1J3I A;  1AO8 A;  1JOL A;  4X5F A;  3QG2 A;  4Q67 A;  1KMS A;  3F0S X;  2INQ A;  3EEM A;  2H2Q A;  2BLC A;  4XT6 A;  3R33 A;  2ANQ A;  2W9T A;  3SRS X;  3SH2 A;  3VCO A;  3GYF A;  1LY3 A;  4KYA A;  4KJK A;  4ELF A;  4Q6A A;  3DL6 A;  5U26 A;  4XE6 X;  3NRR A;  1KLK A;  3DG8 A;  4P3Q A;  5HT4 A;  3FL8 A;  3NTZ A;  5HF0 X;  1DYI A;  2BLA A;  4QLG A;  1OHK A;  3FYW X;  5DFR A;  4XT7 A;  3JWF A;  3DFR A;  1BZF A;  3I3R A;  3L3R A;  3NXX A;  2DHF A;  2HM9 A;  3JVX A;  3SRU X;  4M7U A;  5E8Q A;  4FHB A;  3QL0 A;  1IA4 A;  4P3R A;  3FY8 X;  1DYJ A;  1DG8 A;  3IX9 A;  4DPD A;  3NXV A;  3FS6 A;  3SA2 A;  2P4G A;  1DR5 A;  4IXE D;  4OR7 A;  2HXV A;  5HVB A;  1IA2 A;  5HF2 X;  3ZPC A;  1DG7 A;  4I13 A;  3NXT A;  1U72 A;  4KL9 A;  3Q1H A;  3F8Y A;  3FQO A;  3OAF A;  2C2T A;  3QLS A;  4IXG X;  2KGK A;  3NU0 A;  4OSG A;  5HQZ A;  3ROA A;  1DR4 A;  5HI6 A;  4Q0D A;  4ELB A;  3D80 A;  4RGC A;  1S3U A;  3JWC A;  1BOZ A;  1RX6 A;  3FRB X;  3JW5 A;  3ZPG A;  1LY4 A;  3FQV A;  3GHV A;  1RH3 A;  1RC4 A;  1U71 A;  1HFQ A;  3LG4 A;  4KM0 A;  2O7P A;  3QLX A;  2C2S A;  4KFJ A;  1D1G A;  4XRB A;  3DGA A;  1KMV A;  2G6V A;  4NX6 A;  4PST A;  4KY4 A;  1J3J A;  3JWM A;  4NX7 A;  1M79 A;  3FRF X;  2W3V A;  4ECK A;  3NXO A;  3KJS A;  1DDR A;  1RB3 A;  1RE7 A;  1PDB A;  4PTJ A;  5HSR A;  1VDR A;  3QLR A;  1DRF A;  2BL9 A;  4PSY A;  3QL3 A;  3SRR X;  1LUD A;  1CD2 A;  2W3A A;  3F0B X;  4P68 A;  3F0X X;  5JG0 X;  3E0B A;  5FDA A;  2DRC A;  1DHI A;  4IXF X;  1JOM A;  5HQY A;  1RG7 A;  3RG9 A;  1IA3 A;  2JYB A;  4M7V A;  4EIL A;  4CD2 A;  4KNE A;  6DFR A;  3NXR A;  3GHC A;  1DRA A;  1RA3 A;  4DDR A;  3EEJ A;  5DXV A;  1DIS A;  3EEL A;  1DR3 A;  1RD7 A;  4H95 A;  2CIG A;  2FZI A;  4M2X A;  3NXY A;  1IA1 A;  3KY8 A;  3DAT A;  4PTH A;  3QGT A;  4M6J A;  2XW7 A;  5CC9 A;  1DAJ A; 
#chains in the Genus database with same CATH homology
 4QJC A;  5JA3 A;  4LEK X;  3N0H A;  3JW3 A;  3NZ9 X;  3DRC A;  3CL9 A;  1DR7 A;  3DAU A;  2OBC A;  4KLX A;  3SRQ X;  4DP3 A;  1M78 A;  4G3M A;  3FRE X;  3CSE A;  3HJ3 A;  4TU5 X;  1DF7 A;  1E26 A;  3S7A A;  2D0K A;  1U70 A;  2GD9 A;  2W9S A;  2BLB A;  2ITH A;  3FQF A;  4H98 A;  3GHW A;  3RO9 A;  1S3V A;  2B3Z A;  3HBB A;  2L28 A;  1DLS A;  4M6K A;  4KBN A;  1HFR A;  2W3W A;  4EJ1 A;  4XEC X;  1RX3 A;  1DRB A;  3FQZ A;  2FZJ A;  4LAE X;  1DRH A;  1J3K A;  1RA9 A;  3SGY A;  1VJ3 A;  3SAI A;  2FZH A;  3EIG A;  4G95 A;  3OCH A;  1RF7 A;  2W3B A;  1PD9 A;  3NZA X;  1MVT A;  3IRN A;  1PD8 A;  3FRD X;  1AOE A;  4X5J A;  3QYL A;  1RX1 A;  1DG5 A;  1DHF A;  4KJJ A;  2LF1 A;  4DPH A;  1RA2 A;  1QZF A;  3TQ8 A;  1TDR A;  2D5N A;  7DFR A;  2W9G A;  5HVE A;  3S9U A;  3FRA X;  4QLF A;  3SQY X;  2HQP A;  3JTW A;  4M6L A;  1DRE A;  3NZD A;  2ANO A;  3F8Z A;  3CD2 A;  3M08 A;  4PDJ A;  5EAJ A;  3GI2 A;  3FQ0 A;  1RA8 A;  1RB2 A;  4XT4 A;  3F91 A;  4H96 A;  1S3W A;  5HUI A;  1HFP A;  5HPB A;  3I8A X;  2W3M A;  4ELE A;  3NZB X;  4HOE A;  4FGH A;  3QLY A;  3NZC X;  4XT8 A;  1ZDR A;  3QYO A;  1RA1 A;  5ECX A;  1DDS A;  3QFX A;  3TD8 A;  3INV A;  3D84 X;  4HA7 A;  1OHJ A;  3DL5 A;  1RX9 A;  1DR2 A;  3IA4 A;  3IRM A;  3KGY A;  4DFR A;  1YHO A;  4G8Z X;  3FYV X;  3JSU A;  3K2H A;  4P66 A;  4HOG A;  4X5H A;  2OIP A;  3SR5 X;  3M09 A;  3EX8 A;  3TQB A;  3UM5 A;  3KFY A;  1DYR A;  3F0V X;  4EIZ A;  4PSS A;  1RX7 A;  4KM2 A;  3IRO A;  2CD2 A;  1RX5 A;  3FY9 X;  3TQ9 A;  1DLR A;  4GH8 A;  1M7A A;  2W9H A;  1DYH A;  1DR1 A;  4QI9 A;  3IA5 A;  2ZZA A;  3NZ6 X;  1DHJ A;  1DR6 A;  2AZN A;  4LAH X;  2QK8 A;  5HT5 A;  4ELH A;  4FGG A;  3QLW A;  3K47 A;  3UM8 A;  1AI9 A;  4EIG A;  3QLZ A;  3JWK A;  4ELG A;  3UM6 A;  3KJR A;  1RX2 A;  4KY8 A;  4QLE A;  1CZ3 A;  4HA9 A;  3FL9 A;  4H97 A;  1DIU A;  3EEK A;  4Q0E A;  1RX8 A;  1MVS A;  4QHV A;  4I1N A;  1JUV A;  1S3Y A;  3S3V A;  4LAG X;  4KAK A;  5CCC A;  1RX4 A;  5U27 A;  1SEJ A;  3TQA A;  8DFR A;  3CLB A;  4X5G A;  3SA1 A;  4HOF A;  3F0U X;  3K45 A;  4KJL A;  4XT5 A;  3SRW X;  5HSU A;  3K74 A;  3F0Q X;  3FQC A;  4KD7 A;  5ECC A;  4QJZ D;  4X5I A;  4KEB A;  1J3I A;  1AO8 A;  1JOL A;  4X5F A;  3QG2 A;  4Q67 A;  1KMS A;  3F0S X;  2INQ A;  3EEM A;  2H2Q A;  2BLC A;  4XT6 A;  3R33 A;  2ANQ A;  2W9T A;  3SRS X;  3SH2 A;  3VCO A;  3GYF A;  1LY3 A;  4KYA A;  4KJK A;  4ELF A;  4Q6A A;  3DL6 A;  5U26 A;  4XE6 X;  3NRR A;  1KLK A;  3DG8 A;  4P3Q A;  5HT4 A;  3FL8 A;  3NTZ A;  5HF0 X;  1DYI A;  2BLA A;  4QLG A;  1OHK A;  3FYW X;  5DFR A;  4XT7 A;  3JWF A;  3DFR A;  1BZF A;  3I3R A;  3L3R A;  3NXX A;  2DHF A;  2HM9 A;  3JVX A;  3SRU X;  4M7U A;  5E8Q A;  4FHB A;  3QL0 A;  1IA4 A;  4P3R A;  3FY8 X;  1DYJ A;  1DG8 A;  3IX9 A;  4DPD A;  3NXV A;  3FS6 A;  3SA2 A;  2P4G A;  1DR5 A;  4IXE D;  4OR7 A;  2HXV A;  5HVB A;  1IA2 A;  5HF2 X;  3ZPC A;  1DG7 A;  4I13 A;  3NXT A;  1U72 A;  4KL9 A;  3Q1H A;  3F8Y A;  3FQO A;  3OAF A;  2C2T A;  3QLS A;  4IXG X;  2KGK A;  3NU0 A;  4OSG A;  5HQZ A;  3ROA A;  1DR4 A;  5HI6 A;  4Q0D A;  4ELB A;  3D80 A;  4RGC A;  1S3U A;  3JWC A;  1BOZ A;  1RX6 A;  3FRB X;  3JW5 A;  3ZPG A;  1LY4 A;  3FQV A;  3GHV A;  1RH3 A;  1RC4 A;  1U71 A;  1HFQ A;  3LG4 A;  4KM0 A;  2O7P A;  3QLX A;  2C2S A;  4KFJ A;  1D1G A;  4XRB A;  3DGA A;  1KMV A;  2G6V A;  4NX6 A;  4PST A;  4KY4 A;  1J3J A;  3JWM A;  4NX7 A;  1M79 A;  3FRF X;  2W3V A;  4ECK A;  3NXO A;  3KJS A;  1DDR A;  1RB3 A;  1RE7 A;  1PDB A;  4PTJ A;  5HSR A;  1VDR A;  3QLR A;  1DRF A;  2BL9 A;  4PSY A;  3QL3 A;  3SRR X;  1LUD A;  1CD2 A;  2W3A A;  3F0B X;  4P68 A;  3F0X X;  5JG0 X;  3E0B A;  5FDA A;  2DRC A;  1DHI A;  4IXF X;  1JOM A;  5HQY A;  1RG7 A;  3RG9 A;  1IA3 A;  2JYB A;  4M7V A;  4EIL A;  4CD2 A;  4KNE A;  6DFR A;  3NXR A;  3GHC A;  1DRA A;  1RA3 A;  4DDR A;  3EEJ A;  5DXV A;  1DIS A;  3EEL A;  1DR3 A;  1RD7 A;  4H95 A;  2CIG A;  2FZI A;  4M2X A;  3NXY A;  1IA1 A;  3KY8 A;  3DAT A;  4PTH A;  3QGT A;  4M6J A;  2XW7 A;  5CC9 A;  1DAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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