3RO9A

Candida glabrata dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1006)
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
225
structure length
225
Chain Sequence
KVPVVGIVAALLPEMGIGFQGNLPWRLAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQKFRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGEIYRQSMDLADHWLITKIMPLPETTIPQMDTFLQKQELEQRFYDNSDKLVDFLPSSIQLEGRLTSQEWNGELVKGLPVQEKGYQFYFTLYTKKLEHHHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Candida glabrata
molecule keywords Strain CBS138 chromosome J complete sequence
total genus 59
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3ro9A00
3S3VA 5HF0X 4Q6AA 3QL3A 1KMSA 1DAJA 3EX8A 4NX7A 3DL6A 4IXFX 4XT7A 2W9HA 3FY9X 4KLXA 4KD7A 4CD2A 3FQCA 3E0BA 1RC4A 1RX4A 1RX6A 3INVA 1M7AA 1YHOA 3JWCA 4DPDA 2CD2A 3F8YA 3QGTA 3OAFA 3N0HA 1RX1A 1M79A 1DLSA 3M09A 3JWKA 4XT6A 4I1NA 3UM5A 1PD8A 2ANOA 3F0UX 3GHCA 4LAGX 4QHVA 4PDJA 1IA2A 3F0BX 3M08A 4KY4A 1S3VA 4RGCA 3FRDX 3QLXA 4XRBA 1IA4A 5EAJA 5HSRA 5JG0X 1J3JA 1VJ3A 3FQOA 1LUDA 3NRRA 5HUIA 2W9TA 4PSYA 2C2TA 1DLRA 3JW3A 3I3RA 3EEKA 4G8ZX 1DHFA 1PD9A 4EJ1A 1AOEA 3GI2A 4LEKX 4IXED 3KY8A 4PSTA 3SRWX 2H2QA 4G3MA 3JSUA 3NTZA 3CD2A 2GD9A 3FL8A 1DR7A 3HJ3A 2BLCA 1U70A 4HOFA 3UM8A 3FQFA 2ZZAA 4ELBA 3QYOA 4XT4A 3LG4A 3QLYA 2INQA 3NZCX 3NXOA 4KFJA 1JOLA 4DP3A 4FGHA 3K45A 3QLRA 3IX9A 4Q0EA 4FHBA 4ELHA 5HVBA 7DFRA 4DDRA 2FZHA 1PDBA 4I13A 3SR5X 3CSEA 1DDSA 4ECKA 5ECCA 4KY8A 1U72A 2BLAA 4HA7A 2XW7A 4X5IA 3F0VX 3DGAA 3SA2A 3K47A 3K74A 3QFXA 3SA1A 3K2HA 5HT5A 1RB3A 3FRAX 1DYHA 1RX7A 2W3AA 1DHJA 3SAIA 4KBNA 2HXVA 3JTWA 5U27A 1DR2A 3IRMA 2D0KA 3FQVA 2KGKA 4P3QA 1DYIA 3HBBA 3TD8A 3I8AX 2C2SA 1DF7A 1QZFA 3IRNA 2DHFA 2HQPA 3NXXA 3FL9A 3EELA 1J3IA 3NXTA 1BZFA 1CD2A 2JYBA 1DYJA 4H96A 1M78A 3JWFA 1RA1A 3IA4A 3NZ6X 5CCCA 3ROAA 1DR1A 3IROA 1RX5A 4XT5A 5HSUA 3DG8A 1TDRA 1D1GA 3NZAX 5FDAA 2OIPA 4G95A 3FYWX 2D5NA 4KEBA 2L28A 5HI6A 4M6KA 2OBCA 1JUVA 1DRFA 3DRCA 3FREX 3TQAA 5HT4A 4X5GA 3SQYX 1MVSA 4LAHX 3OCHA 3SH2A 2HM9A 3DAUA 3NZBX 1LY3A 4OR7A 8DFRA 3SRRX 2W3BA 3SGYA 2BL9A 3F8ZA 3FQ0A 4Q0DA 1DYRA 3QL0A 4P3RA 4KYAA 3NXRA 1RE7A 4QLEA 3CLBA 3GHWA 4PTJA 3KJRA 1DISA 3F0QX 2P4GA 3UM6A 5HPBA 1RA8A 2FZIA 1E26A 5JA3A 4KL9A 2LF1A 1U71A 1DREA 3FRFX 3JWMA 1S3YA 3EIGA 3FRBX 4X5JA 4PTHA 2ANQA 4QJZD 3L3RA 3S9UA 3JVXA 3VCOA 5U26A 3NZDA 1DRHA 3TQBA 3F0SX 1DR3A 1DG8A 4PSSA 3ZPCA 5HVEA 2W9SA 2QK8A 1RH3A 3DFRA 3R33A 4KJLA 4QI9A 4FGGA 3F0XX 1DRBA 3FQZA 4X5HA 3JW5A 1RD7A 1LY4A 4M7UA 4XT8A 1RA3A 1RG7A 3QG2A 1DR6A 5HQZA 3RO9A 1BOZA 3EEMA 4NX6A 4HOGA 1HFRA 4DPHA 3SRQX 4Q67A 3EEJA 4M6JA 3RG9A 3Q1HA 4H95A 2ITHA 5E8QA 1S3WA 4P66A 3SRUX 3F91A 3SRSX 4QJCA 2W3WA 1KMVA 3QLZA 1HFQA 5DFRA 3GYFA 1DDRA 1DG7A 1S3UA 1JOMA 1RX2A 2FZJA 3D80A 4DFRA 3KJSA 3NU0A 4QLGA 2DRCA 1HFPA 3S7AA 4QLFA 3D84X 1SEJA 5HF2X 4KAKA 1J3KA 2G6VA 3QLSA 3FY8X 4IXGX 4XE6X 1AI9A 4ELEA 2CIGA 2AZNA 3FYVX 1RX9A 3IA5A 2W3VA 4KJKA 4M6LA 1OHKA 4P68A 1RA2A 1VDRA 5HQYA 4EIZA 1RX8A 3TQ8A 1RX3A 1RF7A 2B3ZA 1MVTA 2O7PA 3GHVA 3NXVA 4KJJA 3CL9A 3DATA 5DXVA 2W3MA 3NXYA 1DR4A 1CZ3A 4HOEA 1IA3A 1KLKA 1DG5A 3KFYA 4X5FA 4M2XA 1RA9A 1RB2A 3NZ9X 4KNEA 1AO8A 1IA1A 1DIUA 1DRAA 3TQ9A 4KM0A 4TU5X 1OHJA 6DFRA 3ZPGA 4EILA 4EIGA 4M7VA 4KM2A 3FS6A 4HA9A 4ELGA 4ELFA 4LAEX 4GH8A 5ECXA 3DL5A 2W9GA 2BLBA 3QLWA 5CC9A 4OSGA 4H98A 4XECX 1DR5A 1DHIA 1ZDRA 3QYLA 3KGYA 4H97A
chains in the Genus database with same CATH superfamily
3S3VA 5HF0X 4Q6AA 3QL3A 1KMSA 1DAJA 3EX8A 4NX7A 3DL6A 4IXFX 4XT7A 2W9HA 3FY9X 4KLXA 4KD7A 4CD2A 3FQCA 3E0BA 1RC4A 1RX4A 1RX6A 3INVA 1M7AA 1YHOA 3JWCA 4DPDA 2CD2A 3F8YA 3QGTA 3OAFA 3N0HA 1RX1A 1M79A 1DLSA 3M09A 3JWKA 4XT6A 4I1NA 3UM5A 1PD8A 2ANOA 3F0UX 3GHCA 4LAGX 4QHVA 4PDJA 1IA2A 3F0BX 3M08A 4KY4A 1S3VA 4RGCA 3FRDX 3QLXA 4XRBA 1IA4A 5EAJA 5HSRA 5JG0X 1J3JA 1VJ3A 3FQOA 1LUDA 3NRRA 5HUIA 2W9TA 4PSYA 2C2TA 1DLRA 3JW3A 3I3RA 3EEKA 4G8ZX 1DHFA 1PD9A 4EJ1A 1AOEA 3GI2A 4LEKX 4IXED 3KY8A 4PSTA 3SRWX 2H2QA 4G3MA 3JSUA 3NTZA 3CD2A 2GD9A 3FL8A 1DR7A 3HJ3A 2BLCA 1U70A 4HOFA 3UM8A 3FQFA 2ZZAA 4ELBA 3QYOA 4XT4A 3LG4A 3QLYA 2INQA 3NZCX 3NXOA 4KFJA 1JOLA 4DP3A 4FGHA 3K45A 3QLRA 3IX9A 4Q0EA 4FHBA 4ELHA 5HVBA 7DFRA 4DDRA 2FZHA 1PDBA 4I13A 3SR5X 3CSEA 1DDSA 4ECKA 5ECCA 4KY8A 1U72A 2BLAA 4HA7A 2XW7A 4X5IA 3F0VX 3DGAA 3SA2A 3K47A 3K74A 3QFXA 3SA1A 3K2HA 5HT5A 1RB3A 3FRAX 1DYHA 1RX7A 2W3AA 1DHJA 3SAIA 4KBNA 2HXVA 3JTWA 5U27A 1DR2A 3IRMA 2D0KA 3FQVA 2KGKA 4P3QA 1DYIA 3HBBA 3TD8A 3I8AX 2C2SA 1DF7A 1QZFA 3IRNA 2DHFA 2HQPA 3NXXA 3FL9A 3EELA 1J3IA 3NXTA 1BZFA 1CD2A 2JYBA 1DYJA 4H96A 1M78A 3JWFA 1RA1A 3IA4A 3NZ6X 5CCCA 3ROAA 1DR1A 3IROA 1RX5A 4XT5A 5HSUA 3DG8A 1TDRA 1D1GA 3NZAX 5FDAA 2OIPA 4G95A 3FYWX 2D5NA 4KEBA 2L28A 5HI6A 4M6KA 2OBCA 1JUVA 1DRFA 3DRCA 3FREX 3TQAA 5HT4A 4X5GA 3SQYX 1MVSA 4LAHX 3OCHA 3SH2A 2HM9A 3DAUA 3NZBX 1LY3A 4OR7A 8DFRA 3SRRX 2W3BA 3SGYA 2BL9A 3F8ZA 3FQ0A 4Q0DA 1DYRA 3QL0A 4P3RA 4KYAA 3NXRA 1RE7A 4QLEA 3CLBA 3GHWA 4PTJA 3KJRA 1DISA 3F0QX 2P4GA 3UM6A 5HPBA 1RA8A 2FZIA 1E26A 5JA3A 4KL9A 2LF1A 1U71A 1DREA 3FRFX 3JWMA 1S3YA 3EIGA 3FRBX 4X5JA 4PTHA 2ANQA 4QJZD 3L3RA 3S9UA 3JVXA 3VCOA 5U26A 3NZDA 1DRHA 3TQBA 3F0SX 1DR3A 1DG8A 4PSSA 3ZPCA 5HVEA 2W9SA 2QK8A 1RH3A 3DFRA 3R33A 4KJLA 4QI9A 4FGGA 3F0XX 1DRBA 3FQZA 4X5HA 3JW5A 1RD7A 1LY4A 4M7UA 4XT8A 1RA3A 1RG7A 3QG2A 1DR6A 5HQZA 3RO9A 1BOZA 3EEMA 4NX6A 4HOGA 1HFRA 4DPHA 3SRQX 4Q67A 3EEJA 4M6JA 3RG9A 3Q1HA 4H95A 2ITHA 5E8QA 1S3WA 4P66A 3SRUX 3F91A 3SRSX 4QJCA 2W3WA 1KMVA 3QLZA 1HFQA 5DFRA 3GYFA 1DDRA 1DG7A 1S3UA 1JOMA 1RX2A 2FZJA 3D80A 4DFRA 3KJSA 3NU0A 4QLGA 2DRCA 1HFPA 3S7AA 4QLFA 3D84X 1SEJA 5HF2X 4KAKA 1J3KA 2G6VA 3QLSA 3FY8X 4IXGX 4XE6X 1AI9A 4ELEA 2CIGA 2AZNA 3FYVX 1RX9A 3IA5A 2W3VA 4KJKA 4M6LA 1OHKA 4P68A 1RA2A 1VDRA 5HQYA 4EIZA 1RX8A 3TQ8A 1RX3A 1RF7A 2B3ZA 1MVTA 2O7PA 3GHVA 3NXVA 4KJJA 3CL9A 3DATA 5DXVA 2W3MA 3NXYA 1DR4A 1CZ3A 4HOEA 1IA3A 1KLKA 1DG5A 3KFYA 4X5FA 4M2XA 1RA9A 1RB2A 3NZ9X 4KNEA 1AO8A 1IA1A 1DIUA 1DRAA 3TQ9A 4KM0A 4TU5X 1OHJA 6DFRA 3ZPGA 4EILA 4EIGA 4M7VA 4KM2A 3FS6A 4HA9A 4ELGA 4ELFA 4LAEX 4GH8A 5ECXA 3DL5A 2W9GA 2BLBA 3QLWA 5CC9A 4OSGA 4H98A 4XECX 1DR5A 1DHIA 1ZDRA 3QYLA 3KGYA 4H97A
chains in the Genus database with same CATH topology
3S3VA 5HF0X 4Q6AA 3QL3A 1KMSA 1DAJA 3EX8A 4NX7A 3DL6A 4IXFX 4XT7A 2W9HA 3FY9X 4KLXA 4KD7A 4CD2A 3FQCA 3E0BA 1RC4A 1RX4A 1RX6A 3INVA 1M7AA 1YHOA 3JWCA 4DPDA 2CD2A 3F8YA 3QGTA 3OAFA 3N0HA 1RX1A 1M79A 1DLSA 3M09A 3JWKA 4XT6A 4I1NA 3UM5A 1PD8A 2ANOA 3F0UX 3GHCA 4LAGX 4QHVA 4PDJA 1IA2A 3F0BX 3M08A 4KY4A 1S3VA 4RGCA 3FRDX 3QLXA 4XRBA 1IA4A 5EAJA 5HSRA 5JG0X 1J3JA 1VJ3A 3FQOA 1LUDA 3NRRA 5HUIA 2W9TA 4PSYA 2C2TA 1DLRA 3JW3A 3I3RA 3EEKA 4G8ZX 1DHFA 1PD9A 4EJ1A 1AOEA 3GI2A 4LEKX 4IXED 3KY8A 4PSTA 3SRWX 2H2QA 4G3MA 3JSUA 3NTZA 3CD2A 2GD9A 3FL8A 1DR7A 3HJ3A 2BLCA 1U70A 4HOFA 3UM8A 3FQFA 2ZZAA 4ELBA 3QYOA 4XT4A 3LG4A 3QLYA 2INQA 3NZCX 3NXOA 4KFJA 1JOLA 4DP3A 4FGHA 3K45A 3QLRA 3IX9A 4Q0EA 4FHBA 4ELHA 5HVBA 7DFRA 4DDRA 2FZHA 1PDBA 4I13A 3SR5X 3CSEA 1DDSA 4ECKA 5ECCA 4KY8A 1U72A 2BLAA 4HA7A 2XW7A 4X5IA 3F0VX 3DGAA 3SA2A 3K47A 3K74A 3QFXA 3SA1A 3K2HA 5HT5A 1RB3A 3FRAX 1DYHA 1RX7A 2W3AA 1DHJA 3SAIA 4KBNA 2HXVA 3JTWA 5U27A 1DR2A 3IRMA 2D0KA 3FQVA 2KGKA 4P3QA 1DYIA 3HBBA 3TD8A 3I8AX 2C2SA 1DF7A 1QZFA 3IRNA 2DHFA 2HQPA 3NXXA 3FL9A 3EELA 1J3IA 3NXTA 1BZFA 1CD2A 2JYBA 1DYJA 4H96A 1M78A 3JWFA 1RA1A 3IA4A 3NZ6X 5CCCA 3ROAA 1DR1A 3IROA 1RX5A 4XT5A 5HSUA 3DG8A 1TDRA 1D1GA 3NZAX 5FDAA 2OIPA 4G95A 3FYWX 2D5NA 4KEBA 2L28A 5HI6A 4M6KA 2OBCA 1JUVA 1DRFA 3DRCA 3FREX 3TQAA 5HT4A 4X5GA 3SQYX 1MVSA 4LAHX 3OCHA 3SH2A 2HM9A 3DAUA 3NZBX 1LY3A 4OR7A 8DFRA 3SRRX 2W3BA 3SGYA 2BL9A 3F8ZA 3FQ0A 4Q0DA 1DYRA 3QL0A 4P3RA 4KYAA 3NXRA 1RE7A 4QLEA 3CLBA 3GHWA 4PTJA 3KJRA 1DISA 3F0QX 2P4GA 3UM6A 5HPBA 1RA8A 2FZIA 1E26A 5JA3A 4KL9A 2LF1A 1U71A 1DREA 3FRFX 3JWMA 1S3YA 3EIGA 3FRBX 4X5JA 4PTHA 2ANQA 4QJZD 3L3RA 3S9UA 3JVXA 3VCOA 5U26A 3NZDA 1DRHA 3TQBA 3F0SX 1DR3A 1DG8A 4PSSA 3ZPCA 5HVEA 2W9SA 2QK8A 1RH3A 3DFRA 3R33A 4KJLA 4QI9A 4FGGA 3F0XX 1DRBA 3FQZA 4X5HA 3JW5A 1RD7A 1LY4A 4M7UA 4XT8A 1RA3A 1RG7A 3QG2A 1DR6A 5HQZA 3RO9A 1BOZA 3EEMA 4NX6A 4HOGA 1HFRA 4DPHA 3SRQX 4Q67A 3EEJA 4M6JA 3RG9A 3Q1HA 4H95A 2ITHA 5E8QA 1S3WA 4P66A 3SRUX 3F91A 3SRSX 4QJCA 2W3WA 1KMVA 3QLZA 1HFQA 5DFRA 3GYFA 1DDRA 1DG7A 1S3UA 1JOMA 1RX2A 2FZJA 3D80A 4DFRA 3KJSA 3NU0A 4QLGA 2DRCA 1HFPA 3S7AA 4QLFA 3D84X 1SEJA 5HF2X 4KAKA 1J3KA 2G6VA 3QLSA 3FY8X 4IXGX 4XE6X 1AI9A 4ELEA 2CIGA 2AZNA 3FYVX 1RX9A 3IA5A 2W3VA 4KJKA 4M6LA 1OHKA 4P68A 1RA2A 1VDRA 5HQYA 4EIZA 1RX8A 3TQ8A 1RX3A 1RF7A 2B3ZA 1MVTA 2O7PA 3GHVA 3NXVA 4KJJA 3CL9A 3DATA 5DXVA 2W3MA 3NXYA 1DR4A 1CZ3A 4HOEA 1IA3A 1KLKA 1DG5A 3KFYA 4X5FA 4M2XA 1RA9A 1RB2A 3NZ9X 4KNEA 1AO8A 1IA1A 1DIUA 1DRAA 3TQ9A 4KM0A 4TU5X 1OHJA 6DFRA 3ZPGA 4EILA 4EIGA 4M7VA 4KM2A 3FS6A 4HA9A 4ELGA 4ELFA 4LAEX 4GH8A 5ECXA 3DL5A 2W9GA 2BLBA 3QLWA 5CC9A 4OSGA 4H98A 4XECX 1DR5A 1DHIA 1ZDRA 3QYLA 3KGYA 4H97A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S3V A;  5HF0 X;  4Q6A A;  3QL3 A;  1KMS A;  1DAJ A;  3EX8 A;  4NX7 A;  3DL6 A;  4IXF X;  4XT7 A;  2W9H A;  3FY9 X;  4KLX A;  4KD7 A;  4CD2 A;  3FQC A;  3E0B A;  1RC4 A;  1RX4 A;  1RX6 A;  3INV A;  1M7A A;  1YHO A;  3JWC A;  4DPD A;  2CD2 A;  3F8Y A;  3QGT A;  3OAF A;  3N0H A;  1RX1 A;  1M79 A;  1DLS A;  3M09 A;  3JWK A;  4XT6 A;  4I1N A;  3UM5 A;  1PD8 A;  2ANO A;  3F0U X;  3GHC A;  4LAG X;  4QHV A;  4PDJ A;  1IA2 A;  3F0B X;  3M08 A;  4KY4 A;  1S3V A;  4RGC A;  3FRD X;  3QLX A;  4XRB A;  1IA4 A;  5EAJ A;  5HSR A;  5JG0 X;  1J3J A;  1VJ3 A;  3FQO A;  1LUD A;  3NRR A;  5HUI A;  2W9T A;  4PSY A;  2C2T A;  1DLR A;  3JW3 A;  3I3R A;  3EEK A;  4G8Z X;  1DHF A;  1PD9 A;  4EJ1 A;  1AOE A;  3GI2 A;  4LEK X;  4IXE D;  3KY8 A;  4PST A;  3SRW X;  2H2Q A;  4G3M A;  3JSU A;  3NTZ A;  3CD2 A;  2GD9 A;  3FL8 A;  1DR7 A;  3HJ3 A;  2BLC A;  1U70 A;  4HOF A;  3UM8 A;  3FQF A;  2ZZA A;  4ELB A;  3QYO A;  4XT4 A;  3LG4 A;  3QLY A;  2INQ A;  3NZC X;  3NXO A;  4KFJ A;  1JOL A;  4DP3 A;  4FGH A;  3K45 A;  3QLR A;  3IX9 A;  4Q0E A;  4FHB A;  4ELH A;  5HVB A;  7DFR A;  4DDR A;  2FZH A;  1PDB A;  4I13 A;  3SR5 X;  3CSE A;  1DDS A;  4ECK A;  5ECC A;  4KY8 A;  1U72 A;  2BLA A;  4HA7 A;  2XW7 A;  4X5I A;  3F0V X;  3DGA A;  3SA2 A;  3K47 A;  3K74 A;  3QFX A;  3SA1 A;  3K2H A;  5HT5 A;  1RB3 A;  3FRA X;  1DYH A;  1RX7 A;  2W3A A;  1DHJ A;  3SAI A;  4KBN A;  2HXV A;  3JTW A;  5U27 A;  1DR2 A;  3IRM A;  2D0K A;  3FQV A;  2KGK A;  4P3Q A;  1DYI A;  3HBB A;  3TD8 A;  3I8A X;  2C2S A;  1DF7 A;  1QZF A;  3IRN A;  2DHF A;  2HQP A;  3NXX A;  3FL9 A;  3EEL A;  1J3I A;  3NXT A;  1BZF A;  1CD2 A;  2JYB A;  1DYJ A;  4H96 A;  1M78 A;  3JWF A;  1RA1 A;  3IA4 A;  3NZ6 X;  5CCC A;  3ROA A;  1DR1 A;  3IRO A;  1RX5 A;  4XT5 A;  5HSU A;  3DG8 A;  1TDR A;  1D1G A;  3NZA X;  5FDA A;  2OIP A;  4G95 A;  3FYW X;  2D5N A;  4KEB A;  2L28 A;  5HI6 A;  4M6K A;  2OBC A;  1JUV A;  1DRF A;  3DRC A;  3FRE X;  3TQA A;  5HT4 A;  4X5G A;  3SQY X;  1MVS A;  4LAH X;  3OCH A;  3SH2 A;  2HM9 A;  3DAU A;  3NZB X;  1LY3 A;  4OR7 A;  8DFR A;  3SRR X;  2W3B A;  3SGY A;  2BL9 A;  3F8Z A;  3FQ0 A;  4Q0D A;  1DYR A;  3QL0 A;  4P3R A;  4KYA A;  3NXR A;  1RE7 A;  4QLE A;  3CLB A;  3GHW A;  4PTJ A;  3KJR A;  1DIS A;  3F0Q X;  2P4G A;  3UM6 A;  5HPB A;  1RA8 A;  2FZI A;  1E26 A;  5JA3 A;  4KL9 A;  2LF1 A;  1U71 A;  1DRE A;  3FRF X;  3JWM A;  1S3Y A;  3EIG A;  3FRB X;  4X5J A;  4PTH A;  2ANQ A;  4QJZ D;  3L3R A;  3S9U A;  3JVX A;  3VCO A;  5U26 A;  3NZD A;  1DRH A;  3TQB A;  3F0S X;  1DR3 A;  1DG8 A;  4PSS A;  3ZPC A;  5HVE A;  2W9S A;  2QK8 A;  1RH3 A;  3DFR A;  3R33 A;  4KJL A;  4QI9 A;  4FGG A;  3F0X X;  1DRB A;  3FQZ A;  4X5H A;  3JW5 A;  1RD7 A;  1LY4 A;  4M7U A;  4XT8 A;  1RA3 A;  1RG7 A;  3QG2 A;  1DR6 A;  5HQZ A;  3RO9 A;  1BOZ A;  3EEM A;  4NX6 A;  4HOG A;  1HFR A;  4DPH A;  3SRQ X;  4Q67 A;  3EEJ A;  4M6J A;  3RG9 A;  3Q1H A;  4H95 A;  2ITH A;  5E8Q A;  1S3W A;  4P66 A;  3SRU X;  3F91 A;  3SRS X;  4QJC A;  2W3W A;  1KMV A;  3QLZ A;  1HFQ A;  5DFR A;  3GYF A;  1DDR A;  1DG7 A;  1S3U A;  1JOM A;  1RX2 A;  2FZJ A;  3D80 A;  4DFR A;  3KJS A;  3NU0 A;  4QLG A;  2DRC A;  1HFP A;  3S7A A;  4QLF A;  3D84 X;  1SEJ A;  5HF2 X;  4KAK A;  1J3K A;  2G6V A;  3QLS A;  3FY8 X;  4IXG X;  4XE6 X;  1AI9 A;  4ELE A;  2CIG A;  2AZN A;  3FYV X;  1RX9 A;  3IA5 A;  2W3V A;  4KJK A;  4M6L A;  1OHK A;  4P68 A;  1RA2 A;  1VDR A;  5HQY A;  4EIZ A;  1RX8 A;  3TQ8 A;  1RX3 A;  1RF7 A;  2B3Z A;  1MVT A;  2O7P A;  3GHV A;  3NXV A;  4KJJ A;  3CL9 A;  3DAT A;  5DXV A;  2W3M A;  3NXY A;  1DR4 A;  1CZ3 A;  4HOE A;  1IA3 A;  1KLK A;  1DG5 A;  3KFY A;  4X5F A;  4M2X A;  1RA9 A;  1RB2 A;  3NZ9 X;  4KNE A;  1AO8 A;  1IA1 A;  1DIU A;  1DRA A;  3TQ9 A;  4KM0 A;  4TU5 X;  1OHJ A;  6DFR A;  3ZPG A;  4EIL A;  4EIG A;  4M7V A;  4KM2 A;  3FS6 A;  4HA9 A;  4ELG A;  4ELF A;  4LAE X;  4GH8 A;  5ECX A;  3DL5 A;  2W9G A;  2BLB A;  3QLW A;  5CC9 A;  4OSG A;  4H98 A;  4XEC X;  1DR5 A;  1DHI A;  1ZDR A;  3QYL A;  3KGY A;  4H97 A; 
#chains in the Genus database with same CATH topology
 3S3V A;  5HF0 X;  4Q6A A;  3QL3 A;  1KMS A;  1DAJ A;  3EX8 A;  4NX7 A;  3DL6 A;  4IXF X;  4XT7 A;  2W9H A;  3FY9 X;  4KLX A;  4KD7 A;  4CD2 A;  3FQC A;  3E0B A;  1RC4 A;  1RX4 A;  1RX6 A;  3INV A;  1M7A A;  1YHO A;  3JWC A;  4DPD A;  2CD2 A;  3F8Y A;  3QGT A;  3OAF A;  3N0H A;  1RX1 A;  1M79 A;  1DLS A;  3M09 A;  3JWK A;  4XT6 A;  4I1N A;  3UM5 A;  1PD8 A;  2ANO A;  3F0U X;  3GHC A;  4LAG X;  4QHV A;  4PDJ A;  1IA2 A;  3F0B X;  3M08 A;  4KY4 A;  1S3V A;  4RGC A;  3FRD X;  3QLX A;  4XRB A;  1IA4 A;  5EAJ A;  5HSR A;  5JG0 X;  1J3J A;  1VJ3 A;  3FQO A;  1LUD A;  3NRR A;  5HUI A;  2W9T A;  4PSY A;  2C2T A;  1DLR A;  3JW3 A;  3I3R A;  3EEK A;  4G8Z X;  1DHF A;  1PD9 A;  4EJ1 A;  1AOE A;  3GI2 A;  4LEK X;  4IXE D;  3KY8 A;  4PST A;  3SRW X;  2H2Q A;  4G3M A;  3JSU A;  3NTZ A;  3CD2 A;  2GD9 A;  3FL8 A;  1DR7 A;  3HJ3 A;  2BLC A;  1U70 A;  4HOF A;  3UM8 A;  3FQF A;  2ZZA A;  4ELB A;  3QYO A;  4XT4 A;  3LG4 A;  3QLY A;  2INQ A;  3NZC X;  3NXO A;  4KFJ A;  1JOL A;  4DP3 A;  4FGH A;  3K45 A;  3QLR A;  3IX9 A;  4Q0E A;  4FHB A;  4ELH A;  5HVB A;  7DFR A;  4DDR A;  2FZH A;  1PDB A;  4I13 A;  3SR5 X;  3CSE A;  1DDS A;  4ECK A;  5ECC A;  4KY8 A;  1U72 A;  2BLA A;  4HA7 A;  2XW7 A;  4X5I A;  3F0V X;  3DGA A;  3SA2 A;  3K47 A;  3K74 A;  3QFX A;  3SA1 A;  3K2H A;  5HT5 A;  1RB3 A;  3FRA X;  1DYH A;  1RX7 A;  2W3A A;  1DHJ A;  3SAI A;  4KBN A;  2HXV A;  3JTW A;  5U27 A;  1DR2 A;  3IRM A;  2D0K A;  3FQV A;  2KGK A;  4P3Q A;  1DYI A;  3HBB A;  3TD8 A;  3I8A X;  2C2S A;  1DF7 A;  1QZF A;  3IRN A;  2DHF A;  2HQP A;  3NXX A;  3FL9 A;  3EEL A;  1J3I A;  3NXT A;  1BZF A;  1CD2 A;  2JYB A;  1DYJ A;  4H96 A;  1M78 A;  3JWF A;  1RA1 A;  3IA4 A;  3NZ6 X;  5CCC A;  3ROA A;  1DR1 A;  3IRO A;  1RX5 A;  4XT5 A;  5HSU A;  3DG8 A;  1TDR A;  1D1G A;  3NZA X;  5FDA A;  2OIP A;  4G95 A;  3FYW X;  2D5N A;  4KEB A;  2L28 A;  5HI6 A;  4M6K A;  2OBC A;  1JUV A;  1DRF A;  3DRC A;  3FRE X;  3TQA A;  5HT4 A;  4X5G A;  3SQY X;  1MVS A;  4LAH X;  3OCH A;  3SH2 A;  2HM9 A;  3DAU A;  3NZB X;  1LY3 A;  4OR7 A;  8DFR A;  3SRR X;  2W3B A;  3SGY A;  2BL9 A;  3F8Z A;  3FQ0 A;  4Q0D A;  1DYR A;  3QL0 A;  4P3R A;  4KYA A;  3NXR A;  1RE7 A;  4QLE A;  3CLB A;  3GHW A;  4PTJ A;  3KJR A;  1DIS A;  3F0Q X;  2P4G A;  3UM6 A;  5HPB A;  1RA8 A;  2FZI A;  1E26 A;  5JA3 A;  4KL9 A;  2LF1 A;  1U71 A;  1DRE A;  3FRF X;  3JWM A;  1S3Y A;  3EIG A;  3FRB X;  4X5J A;  4PTH A;  2ANQ A;  4QJZ D;  3L3R A;  3S9U A;  3JVX A;  3VCO A;  5U26 A;  3NZD A;  1DRH A;  3TQB A;  3F0S X;  1DR3 A;  1DG8 A;  4PSS A;  3ZPC A;  5HVE A;  2W9S A;  2QK8 A;  1RH3 A;  3DFR A;  3R33 A;  4KJL A;  4QI9 A;  4FGG A;  3F0X X;  1DRB A;  3FQZ A;  4X5H A;  3JW5 A;  1RD7 A;  1LY4 A;  4M7U A;  4XT8 A;  1RA3 A;  1RG7 A;  3QG2 A;  1DR6 A;  5HQZ A;  3RO9 A;  1BOZ A;  3EEM A;  4NX6 A;  4HOG A;  1HFR A;  4DPH A;  3SRQ X;  4Q67 A;  3EEJ A;  4M6J A;  3RG9 A;  3Q1H A;  4H95 A;  2ITH A;  5E8Q A;  1S3W A;  4P66 A;  3SRU X;  3F91 A;  3SRS X;  4QJC A;  2W3W A;  1KMV A;  3QLZ A;  1HFQ A;  5DFR A;  3GYF A;  1DDR A;  1DG7 A;  1S3U A;  1JOM A;  1RX2 A;  2FZJ A;  3D80 A;  4DFR A;  3KJS A;  3NU0 A;  4QLG A;  2DRC A;  1HFP A;  3S7A A;  4QLF A;  3D84 X;  1SEJ A;  5HF2 X;  4KAK A;  1J3K A;  2G6V A;  3QLS A;  3FY8 X;  4IXG X;  4XE6 X;  1AI9 A;  4ELE A;  2CIG A;  2AZN A;  3FYV X;  1RX9 A;  3IA5 A;  2W3V A;  4KJK A;  4M6L A;  1OHK A;  4P68 A;  1RA2 A;  1VDR A;  5HQY A;  4EIZ A;  1RX8 A;  3TQ8 A;  1RX3 A;  1RF7 A;  2B3Z A;  1MVT A;  2O7P A;  3GHV A;  3NXV A;  4KJJ A;  3CL9 A;  3DAT A;  5DXV A;  2W3M A;  3NXY A;  1DR4 A;  1CZ3 A;  4HOE A;  1IA3 A;  1KLK A;  1DG5 A;  3KFY A;  4X5F A;  4M2X A;  1RA9 A;  1RB2 A;  3NZ9 X;  4KNE A;  1AO8 A;  1IA1 A;  1DIU A;  1DRA A;  3TQ9 A;  4KM0 A;  4TU5 X;  1OHJ A;  6DFR A;  3ZPG A;  4EIL A;  4EIG A;  4M7V A;  4KM2 A;  3FS6 A;  4HA9 A;  4ELG A;  4ELF A;  4LAE X;  4GH8 A;  5ECX A;  3DL5 A;  2W9G A;  2BLB A;  3QLW A;  5CC9 A;  4OSG A;  4H98 A;  4XEC X;  1DR5 A;  1DHI A;  1ZDR A;  3QYL A;  3KGY A;  4H97 A; 
#chains in the Genus database with same CATH homology
 3S3V A;  5HF0 X;  4Q6A A;  3QL3 A;  1KMS A;  1DAJ A;  3EX8 A;  4NX7 A;  3DL6 A;  4IXF X;  4XT7 A;  2W9H A;  3FY9 X;  4KLX A;  4KD7 A;  4CD2 A;  3FQC A;  3E0B A;  1RC4 A;  1RX4 A;  1RX6 A;  3INV A;  1M7A A;  1YHO A;  3JWC A;  4DPD A;  2CD2 A;  3F8Y A;  3QGT A;  3OAF A;  3N0H A;  1RX1 A;  1M79 A;  1DLS A;  3M09 A;  3JWK A;  4XT6 A;  4I1N A;  3UM5 A;  1PD8 A;  2ANO A;  3F0U X;  3GHC A;  4LAG X;  4QHV A;  4PDJ A;  1IA2 A;  3F0B X;  3M08 A;  4KY4 A;  1S3V A;  4RGC A;  3FRD X;  3QLX A;  4XRB A;  1IA4 A;  5EAJ A;  5HSR A;  5JG0 X;  1J3J A;  1VJ3 A;  3FQO A;  1LUD A;  3NRR A;  5HUI A;  2W9T A;  4PSY A;  2C2T A;  1DLR A;  3JW3 A;  3I3R A;  3EEK A;  4G8Z X;  1DHF A;  1PD9 A;  4EJ1 A;  1AOE A;  3GI2 A;  4LEK X;  4IXE D;  3KY8 A;  4PST A;  3SRW X;  2H2Q A;  4G3M A;  3JSU A;  3NTZ A;  3CD2 A;  2GD9 A;  3FL8 A;  1DR7 A;  3HJ3 A;  2BLC A;  1U70 A;  4HOF A;  3UM8 A;  3FQF A;  2ZZA A;  4ELB A;  3QYO A;  4XT4 A;  3LG4 A;  3QLY A;  2INQ A;  3NZC X;  3NXO A;  4KFJ A;  1JOL A;  4DP3 A;  4FGH A;  3K45 A;  3QLR A;  3IX9 A;  4Q0E A;  4FHB A;  4ELH A;  5HVB A;  7DFR A;  4DDR A;  2FZH A;  1PDB A;  4I13 A;  3SR5 X;  3CSE A;  1DDS A;  4ECK A;  5ECC A;  4KY8 A;  1U72 A;  2BLA A;  4HA7 A;  2XW7 A;  4X5I A;  3F0V X;  3DGA A;  3SA2 A;  3K47 A;  3K74 A;  3QFX A;  3SA1 A;  3K2H A;  5HT5 A;  1RB3 A;  3FRA X;  1DYH A;  1RX7 A;  2W3A A;  1DHJ A;  3SAI A;  4KBN A;  2HXV A;  3JTW A;  5U27 A;  1DR2 A;  3IRM A;  2D0K A;  3FQV A;  2KGK A;  4P3Q A;  1DYI A;  3HBB A;  3TD8 A;  3I8A X;  2C2S A;  1DF7 A;  1QZF A;  3IRN A;  2DHF A;  2HQP A;  3NXX A;  3FL9 A;  3EEL A;  1J3I A;  3NXT A;  1BZF A;  1CD2 A;  2JYB A;  1DYJ A;  4H96 A;  1M78 A;  3JWF A;  1RA1 A;  3IA4 A;  3NZ6 X;  5CCC A;  3ROA A;  1DR1 A;  3IRO A;  1RX5 A;  4XT5 A;  5HSU A;  3DG8 A;  1TDR A;  1D1G A;  3NZA X;  5FDA A;  2OIP A;  4G95 A;  3FYW X;  2D5N A;  4KEB A;  2L28 A;  5HI6 A;  4M6K A;  2OBC A;  1JUV A;  1DRF A;  3DRC A;  3FRE X;  3TQA A;  5HT4 A;  4X5G A;  3SQY X;  1MVS A;  4LAH X;  3OCH A;  3SH2 A;  2HM9 A;  3DAU A;  3NZB X;  1LY3 A;  4OR7 A;  8DFR A;  3SRR X;  2W3B A;  3SGY A;  2BL9 A;  3F8Z A;  3FQ0 A;  4Q0D A;  1DYR A;  3QL0 A;  4P3R A;  4KYA A;  3NXR A;  1RE7 A;  4QLE A;  3CLB A;  3GHW A;  4PTJ A;  3KJR A;  1DIS A;  3F0Q X;  2P4G A;  3UM6 A;  5HPB A;  1RA8 A;  2FZI A;  1E26 A;  5JA3 A;  4KL9 A;  2LF1 A;  1U71 A;  1DRE A;  3FRF X;  3JWM A;  1S3Y A;  3EIG A;  3FRB X;  4X5J A;  4PTH A;  2ANQ A;  4QJZ D;  3L3R A;  3S9U A;  3JVX A;  3VCO A;  5U26 A;  3NZD A;  1DRH A;  3TQB A;  3F0S X;  1DR3 A;  1DG8 A;  4PSS A;  3ZPC A;  5HVE A;  2W9S A;  2QK8 A;  1RH3 A;  3DFR A;  3R33 A;  4KJL A;  4QI9 A;  4FGG A;  3F0X X;  1DRB A;  3FQZ A;  4X5H A;  3JW5 A;  1RD7 A;  1LY4 A;  4M7U A;  4XT8 A;  1RA3 A;  1RG7 A;  3QG2 A;  1DR6 A;  5HQZ A;  3RO9 A;  1BOZ A;  3EEM A;  4NX6 A;  4HOG A;  1HFR A;  4DPH A;  3SRQ X;  4Q67 A;  3EEJ A;  4M6J A;  3RG9 A;  3Q1H A;  4H95 A;  2ITH A;  5E8Q A;  1S3W A;  4P66 A;  3SRU X;  3F91 A;  3SRS X;  4QJC A;  2W3W A;  1KMV A;  3QLZ A;  1HFQ A;  5DFR A;  3GYF A;  1DDR A;  1DG7 A;  1S3U A;  1JOM A;  1RX2 A;  2FZJ A;  3D80 A;  4DFR A;  3KJS A;  3NU0 A;  4QLG A;  2DRC A;  1HFP A;  3S7A A;  4QLF A;  3D84 X;  1SEJ A;  5HF2 X;  4KAK A;  1J3K A;  2G6V A;  3QLS A;  3FY8 X;  4IXG X;  4XE6 X;  1AI9 A;  4ELE A;  2CIG A;  2AZN A;  3FYV X;  1RX9 A;  3IA5 A;  2W3V A;  4KJK A;  4M6L A;  1OHK A;  4P68 A;  1RA2 A;  1VDR A;  5HQY A;  4EIZ A;  1RX8 A;  3TQ8 A;  1RX3 A;  1RF7 A;  2B3Z A;  1MVT A;  2O7P A;  3GHV A;  3NXV A;  4KJJ A;  3CL9 A;  3DAT A;  5DXV A;  2W3M A;  3NXY A;  1DR4 A;  1CZ3 A;  4HOE A;  1IA3 A;  1KLK A;  1DG5 A;  3KFY A;  4X5F A;  4M2X A;  1RA9 A;  1RB2 A;  3NZ9 X;  4KNE A;  1AO8 A;  1IA1 A;  1DIU A;  1DRA A;  3TQ9 A;  4KM0 A;  4TU5 X;  1OHJ A;  6DFR A;  3ZPG A;  4EIL A;  4EIG A;  4M7V A;  4KM2 A;  3FS6 A;  4HA9 A;  4ELG A;  4ELF A;  4LAE X;  4GH8 A;  5ECX A;  3DL5 A;  2W9G A;  2BLB A;  3QLW A;  5CC9 A;  4OSG A;  4H98 A;  4XEC X;  1DR5 A;  1DHI A;  1ZDR A;  3QYL A;  3KGY A;  4H97 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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